-
1
-
-
3142768347
-
Chromatin regulates origin activity in Drosophila follicle cells
-
Aggarwal B.D., Calvi B.R. Chromatin regulates origin activity in Drosophila follicle cells. Nature 2004, 430:372-376.
-
(2004)
Nature
, vol.430
, pp. 372-376
-
-
Aggarwal, B.D.1
Calvi, B.R.2
-
2
-
-
35348849572
-
Differentiated horizontal interneurons clonally expand to form metastatic retinoblastoma in mice
-
Ajioka I., Martins R.A., Bayazitov I.T., Donovan S., Johnson D.A., Frase S., Cicero S.A., Boyd K., Zakharenko S.S., Dyer M.A. Differentiated horizontal interneurons clonally expand to form metastatic retinoblastoma in mice. Cell 2007, 131:378-390.
-
(2007)
Cell
, vol.131
, pp. 378-390
-
-
Ajioka, I.1
Martins, R.A.2
Bayazitov, I.T.3
Donovan, S.4
Johnson, D.A.5
Frase, S.6
Cicero, S.A.7
Boyd, K.8
Zakharenko, S.S.9
Dyer, M.A.10
-
3
-
-
70749128701
-
RNAi mediated acute depletion of retinoblastoma protein (pRb) promotes aneuploidy in human primary cells via micronuclei formation
-
Amato A., Lentini L., Schillaci T., Iovino F., Di Leonardo A. RNAi mediated acute depletion of retinoblastoma protein (pRb) promotes aneuploidy in human primary cells via micronuclei formation. BMC Cell Biol. 2009, 10:79.
-
(2009)
BMC Cell Biol.
, vol.10
, pp. 79
-
-
Amato, A.1
Lentini, L.2
Schillaci, T.3
Iovino, F.4
Di Leonardo, A.5
-
4
-
-
2942568553
-
RB reversibly inhibits DNA replication via two temporally distinct mechanisms
-
Angus S.P., Mayhew C.N., Solomon D.A., Braden W.A., Markey M.P., Okuno Y., Cardoso M.C., Gilbert D.M., Knudsen E.S. RB reversibly inhibits DNA replication via two temporally distinct mechanisms. Mol. Cell. Biol. 2004, 24:5404-5420.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 5404-5420
-
-
Angus, S.P.1
Mayhew, C.N.2
Solomon, D.A.3
Braden, W.A.4
Markey, M.P.5
Okuno, Y.6
Cardoso, M.C.7
Gilbert, D.M.8
Knudsen, E.S.9
-
5
-
-
68249090581
-
The CDK4-pRB-E2F1 pathway controls insulin secretion
-
Annicotte J.S., Blanchet E., Chavey C., Iankova I., Costes S., Assou S., Teyssier J., Dalle S., Sardet C., Fajas L. The CDK4-pRB-E2F1 pathway controls insulin secretion. Nat. Cell Biol. 2009, 11:1017-1023.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 1017-1023
-
-
Annicotte, J.S.1
Blanchet, E.2
Chavey, C.3
Iankova, I.4
Costes, S.5
Assou, S.6
Teyssier, J.7
Dalle, S.8
Sardet, C.9
Fajas, L.10
-
6
-
-
0345060052
-
Recapitulation of the effects of the human papillomavirus type 16 E7 oncogene on mouse epithelium by somatic Rb deletion and detection of pRb-independent effects of E7 in vivo
-
Balsitis S.J., Sage J., Duensing S., Munger K., Jacks T., Lambert P.F. Recapitulation of the effects of the human papillomavirus type 16 E7 oncogene on mouse epithelium by somatic Rb deletion and detection of pRb-independent effects of E7 in vivo. Mol. Cell. Biol. 2003, 23:9094-9103.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 9094-9103
-
-
Balsitis, S.J.1
Sage, J.2
Duensing, S.3
Munger, K.4
Jacks, T.5
Lambert, P.F.6
-
7
-
-
16244378910
-
Control of cell proliferation in the Drosophila eye by Notch signaling
-
Baonza A., Freeman M. Control of cell proliferation in the Drosophila eye by Notch signaling. Dev. Cell 2005, 8:529-539.
-
(2005)
Dev. Cell
, vol.8
, pp. 529-539
-
-
Baonza, A.1
Freeman, M.2
-
8
-
-
0034719409
-
Glutamic acid mutagenesis of retinoblastoma protein phosphorylation sites has diverse effects on function
-
Barrientes S., Cooke C., Goodrich D.W. Glutamic acid mutagenesis of retinoblastoma protein phosphorylation sites has diverse effects on function. Oncogene 2000, 19:562-570.
-
(2000)
Oncogene
, vol.19
, pp. 562-570
-
-
Barrientes, S.1
Cooke, C.2
Goodrich, D.W.3
-
9
-
-
18144378722
-
Retinoblastoma and the related pocket protein p107 act as coactivators of neuroD1 to enhance gene transcription
-
Batsche E., Moschopoulos P., Desroches J., Bilodeau S., Drouin J. Retinoblastoma and the related pocket protein p107 act as coactivators of neuroD1 to enhance gene transcription. J. Biol. Chem. 2005, 280:16088-16095.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 16088-16095
-
-
Batsche, E.1
Moschopoulos, P.2
Desroches, J.3
Bilodeau, S.4
Drouin, J.5
-
10
-
-
33750463354
-
MES-4: An autosome-associated histone methyltransferase that participates in silencing the X chromosomes in the C. elegans germ line
-
Bender L.B., Suh J., Carroll C.R., Fong Y., Fingerman I.M., Briggs S.D., Cao R., Zhang Y., Reinke V., Strome S. MES-4: An autosome-associated histone methyltransferase that participates in silencing the X chromosomes in the C. elegans germ line. Development 2006, 133:3907-3917.
-
(2006)
Development
, vol.133
, pp. 3907-3917
-
-
Bender, L.B.1
Suh, J.2
Carroll, C.R.3
Fong, Y.4
Fingerman, I.M.5
Briggs, S.D.6
Cao, R.7
Zhang, Y.8
Reinke, V.9
Strome, S.10
-
11
-
-
20444429760
-
Binding of pRB to the PHD protein RBP2 promotes cellular differentiation
-
Benevolenskaya E.V., Murray H.L., Branton P., Young R.A., Kaelin W.G. Binding of pRB to the PHD protein RBP2 promotes cellular differentiation. Mol. Cell 2005, 18:623-635.
-
(2005)
Mol. Cell
, vol.18
, pp. 623-635
-
-
Benevolenskaya, E.V.1
Murray, H.L.2
Branton, P.3
Young, R.A.4
Kaelin, W.G.5
-
12
-
-
14644410453
-
The signals and pathways activating cellular senescence
-
Ben-Porath I., Weinberg R.A., Ben-Porath I., Weinberg R.A. The signals and pathways activating cellular senescence. Int. J. Biochem. Cell Biol. 2005, 37:961-976.
-
(2005)
Int. J. Biochem. Cell Biol.
, vol.37
, pp. 961-976
-
-
Ben-Porath, I.1
Weinberg, R.A.2
Ben-Porath, I.3
Weinberg, R.A.4
-
13
-
-
50149110590
-
Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage
-
Berman S.D., Calo E., Landman A.S., Danielian P.S., Miller E.S., West J.C., Fonhoue B.D., Caron A., Bronson R., Bouxsein M.L., Mukherjee S., Lees J.A. Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage. Proc. Natl. Acad. Sci. USA 2008, 105:11851-11856.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 11851-11856
-
-
Berman, S.D.1
Calo, E.2
Landman, A.S.3
Danielian, P.S.4
Miller, E.S.5
West, J.C.6
Fonhoue, B.D.7
Caron, A.8
Bronson, R.9
Bouxsein, M.L.10
Mukherjee, S.11
Lees, J.A.12
-
14
-
-
33947246502
-
Retinoblastoma protein and anaphase-promoting complex physically interact and functionally cooperate during cell-cycle exit
-
Binne U.K., Classon M.K., Dick F.A., Wei W., Rape M., Kaelin W.G., Naar A.M., Dyson N.J. Retinoblastoma protein and anaphase-promoting complex physically interact and functionally cooperate during cell-cycle exit. Nat. Cell Biol. 2007, 9:225-232.
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 225-232
-
-
Binne, U.K.1
Classon, M.K.2
Dick, F.A.3
Wei, W.4
Rape, M.5
Kaelin, W.G.6
Naar, A.M.7
Dyson, N.J.8
-
15
-
-
77955911829
-
Arabidopsis retinoblastoma-related is required for stem cell maintenance, cell differentiation, and lateral organ production
-
22, 1792-1811
-
Borghi L., Gutzat R., Futterer J., Laizet Y.h., Hennig L., Gruissem W. Arabidopsis retinoblastoma-related is required for stem cell maintenance, cell differentiation, and lateral organ production. Plant Cell 2010, 22, 1792-1811.
-
(2010)
Plant Cell
-
-
Borghi, L.1
Gutzat, R.2
Futterer, J.3
Laizet, Y.4
Hennig, L.5
Gruissem, W.6
-
16
-
-
0035092886
-
DNA replication control through interaction of E2F-RB and the origin recognition complex
-
Bosco G., Du W., Orr-Weaver T.L. DNA replication control through interaction of E2F-RB and the origin recognition complex. Nat. Cell Biol. 2001, 3:289-295.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 289-295
-
-
Bosco, G.1
Du, W.2
Orr-Weaver, T.L.3
-
17
-
-
0035169269
-
Lin-35 Rb and cki-1 Cip/Kip cooperate in developmental regulation of G1 progression in C. elegans
-
Boxem M., van den Heuvel S. lin-35 Rb and cki-1 Cip/Kip cooperate in developmental regulation of G1 progression in C. elegans. Development 2001, 128:4349-4359.
-
(2001)
Development
, vol.128
, pp. 4349-4359
-
-
Boxem, M.1
van den Heuvel, S.2
-
18
-
-
0037018845
-
C. elegans class B synthetic multivulva genes act in G(1) regulation
-
Boxem M., van den Heuvel S. C. elegans class B synthetic multivulva genes act in G(1) regulation. Curr. Biol. 2002, 12:906-911.
-
(2002)
Curr. Biol.
, vol.12
, pp. 906-911
-
-
Boxem, M.1
van den Heuvel, S.2
-
19
-
-
0032484989
-
Retinoblastoma protein recruits histone deacetylase to repress transcription
-
Brehm A., Miska E.A., McCance D.J., Reid J.L., Bannister A.J., Kouzarides T. Retinoblastoma protein recruits histone deacetylase to repress transcription. Nature 1998, 391:597-601.
-
(1998)
Nature
, vol.391
, pp. 597-601
-
-
Brehm, A.1
Miska, E.A.2
McCance, D.J.3
Reid, J.L.4
Bannister, A.J.5
Kouzarides, T.6
-
20
-
-
0032931991
-
Cumulative effect of phosphorylation of pRB on regulation of E2F activity
-
Brown V.D., Phillips R.A., Gallie B.L. Cumulative effect of phosphorylation of pRB on regulation of E2F activity. Mol. Cell. Biol. 1999, 19:3246-3256.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 3246-3256
-
-
Brown, V.D.1
Phillips, R.A.2
Gallie, B.L.3
-
21
-
-
77952387813
-
Phosphorylation-induced conformational changes in the retinoblastoma protein inhibit E2F transactivation domain binding
-
Burke J.R., Deshong A.J., Pelton J.G., Rubin S.M. Phosphorylation-induced conformational changes in the retinoblastoma protein inhibit E2F transactivation domain binding. J. Biol. Chem. 2010, 285:16286-16293.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 16286-16293
-
-
Burke, J.R.1
Deshong, A.J.2
Pelton, J.G.3
Rubin, S.M.4
-
22
-
-
50149120366
-
Cellular mechanisms of tumour suppression by the retinoblastoma gene
-
Burkhart D.L., Sage J. Cellular mechanisms of tumour suppression by the retinoblastoma gene. Nat. Rev. Cancer 2008, 8:671-682.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 671-682
-
-
Burkhart, D.L.1
Sage, J.2
-
23
-
-
77949408525
-
Regulation of RB transcription in vivo by RB family members
-
Burkhart D.L., Ngai L.K., Roake C.M., Viatour P., Thangavel C., Ho V.M., Knudsen E.S., Sage J. Regulation of RB transcription in vivo by RB family members. Mol. Cell. Biol. 2010, 30:1729-1745.
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 1729-1745
-
-
Burkhart, D.L.1
Ngai, L.K.2
Roake, C.M.3
Viatour, P.4
Thangavel, C.5
Ho, V.M.6
Knudsen, E.S.7
Sage, J.8
-
24
-
-
0035265833
-
Dpl-1 DP and efl-1 E2F act with lin-35 Rb to antagonize Ras signaling in C. elegans vulval development
-
Ceol C.J., Horvitz H.R. dpl-1 DP and efl-1 E2F act with lin-35 Rb to antagonize Ras signaling in C. elegans vulval development. Mol. Cell 2001, 7:461-473.
-
(2001)
Mol. Cell
, vol.7
, pp. 461-473
-
-
Ceol, C.J.1
Horvitz, H.R.2
-
25
-
-
0034944423
-
Acetylation control of the retinoblastoma tumour-suppressor protein
-
Chan H.M., Krstic-Demonacos M., Smith L., Demonacos C., La Thangue N.B. Acetylation control of the retinoblastoma tumour-suppressor protein. Nat. Cell Biol. 2001, 3:667-674.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 667-674
-
-
Chan, H.M.1
Krstic-Demonacos, M.2
Smith, L.3
Demonacos, C.4
La Thangue, N.B.5
-
26
-
-
0037313618
-
Coordinated regulation of life and death by RB
-
Chau B.N., Wang J.Y., Chau B.N., Wang J.Y.J. Coordinated regulation of life and death by RB. Nat. Rev. Cancer 2003, 3:130-138.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 130-138
-
-
Chau, B.N.1
Wang, J.Y.2
Chau, B.N.3
Wang, J.Y.J.4
-
27
-
-
41149159603
-
Cell cycle association of the retinoblastoma protein Rb and the histone demethylase LSD1 with the Epstein-Barr virus latency promoter Cp
-
Chau C.M., Deng Z., Kang H., Lieberman P.M. Cell cycle association of the retinoblastoma protein Rb and the histone demethylase LSD1 with the Epstein-Barr virus latency promoter Cp. J. Virol. 2008, 82:3428-3437.
-
(2008)
J. Virol.
, vol.82
, pp. 3428-3437
-
-
Chau, C.M.1
Deng, Z.2
Kang, H.3
Lieberman, P.M.4
-
28
-
-
0030031409
-
Retinoblastoma protein directly interacts with and activates the transcription factor NF-IL6
-
Chen P.L., Riley D.J., Chen-Kiang S., Lee W.H. Retinoblastoma protein directly interacts with and activates the transcription factor NF-IL6. Proc. Natl. Acad. Sci. USA 1996, 93:465-469.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 465-469
-
-
Chen, P.L.1
Riley, D.J.2
Chen-Kiang, S.3
Lee, W.H.4
-
29
-
-
0029830342
-
Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs
-
Chen P.L., Riley D.J., Chen Y., Lee W.H. Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs. Genes Dev. 1996, 10:2794-2804.
-
(1996)
Genes Dev.
, vol.10
, pp. 2794-2804
-
-
Chen, P.L.1
Riley, D.J.2
Chen, Y.3
Lee, W.H.4
-
30
-
-
2942574955
-
Cell-specific effects of RB or RB/p107 loss on retinal development implicate an intrinsically death-resistant cell-of-origin in retinoblastoma
-
Chen D., Livne-bar I., Vanderluit J.L., Slack R.S., Agochiya M., Bremner R. Cell-specific effects of RB or RB/p107 loss on retinal development implicate an intrinsically death-resistant cell-of-origin in retinoblastoma. Cancer Cell 2004, 5:539-551.
-
(2004)
Cancer Cell
, vol.5
, pp. 539-551
-
-
Chen, D.1
Livne-bar, I.2
Vanderluit, J.L.3
Slack, R.S.4
Agochiya, M.5
Bremner, R.6
-
31
-
-
34547108871
-
Rb-mediated neuronal differentiation through cell-cycle-independent regulation of E2f3a
-
Chen D., Opavsky R., Pacal M., Tanimoto N., Wenzel P., Seeliger M.W., Leone G., Bremner R. Rb-mediated neuronal differentiation through cell-cycle-independent regulation of E2f3a. PLoS Biol. 2007, 5:e179.
-
(2007)
PLoS Biol.
, vol.5
-
-
Chen, D.1
Opavsky, R.2
Pacal, M.3
Tanimoto, N.4
Wenzel, P.5
Seeliger, M.W.6
Leone, G.7
Bremner, R.8
-
32
-
-
70350518233
-
Emerging roles of E2Fs in cancer: An exit from cell cycle control
-
Chen H.Z., Tsai S.Y., Leone G. Emerging roles of E2Fs in cancer: An exit from cell cycle control. Nat. Rev. Cancer 2009, 9:785-797.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 785-797
-
-
Chen, H.Z.1
Tsai, S.Y.2
Leone, G.3
-
33
-
-
66349139380
-
Proliferation and cell fate establishment during Arabidopsis male gametogenesis depends on the Retinoblastoma protein
-
Chen Z., Hafidh S., Poh S.H., Twell D., Berger F. Proliferation and cell fate establishment during Arabidopsis male gametogenesis depends on the Retinoblastoma protein. Proc. Natl. Acad. Sci. USA 2009, 106:7257-7262.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 7257-7262
-
-
Chen, Z.1
Hafidh, S.2
Poh, S.H.3
Twell, D.4
Berger, F.5
-
34
-
-
77950486542
-
Dissecting the unique role of the retinoblastoma tumor suppressor during cellular senescence
-
Chicas A., Wang X., Zhang C., McCurrach M., Zhao Z., Mert O., Dickins R.A., Narita M., Zhang M., Lowe S.W. Dissecting the unique role of the retinoblastoma tumor suppressor during cellular senescence. Cancer Cell 2010, 17:376-387.
-
(2010)
Cancer Cell
, vol.17
, pp. 376-387
-
-
Chicas, A.1
Wang, X.2
Zhang, C.3
McCurrach, M.4
Zhao, Z.5
Mert, O.6
Dickins, R.A.7
Narita, M.8
Zhang, M.9
Lowe, S.W.10
-
35
-
-
33947245128
-
RBP2 belongs to a family of demethylases, specific for tri- and dimethylated lysine 4 on histone 3
-
Christensen J., Agger K., Cloos P.A., Pasini D., Rose S., Sennels L., Rappsilber J., Hansen K.H., Salcini A.E., Helin K. RBP2 belongs to a family of demethylases, specific for tri- and dimethylated lysine 4 on histone 3. Cell 2007, 128:1063-1076.
-
(2007)
Cell
, vol.128
, pp. 1063-1076
-
-
Christensen, J.1
Agger, K.2
Cloos, P.A.3
Pasini, D.4
Rose, S.5
Sennels, L.6
Rappsilber, J.7
Hansen, K.H.8
Salcini, A.E.9
Helin, K.10
-
36
-
-
0026760426
-
Requirement for a functional Rb-1 gene in murine development
-
Clarke A.R., Maandag E.R., van Roon M., van der Lugt N.M., van der Valk M., Hooper M.L., Berns A., te Riele H. Requirement for a functional Rb-1 gene in murine development. Nature 1992, 359:328-330.
-
(1992)
Nature
, vol.359
, pp. 328-330
-
-
Clarke, A.R.1
Maandag, E.R.2
van Roon, M.3
van der Lugt, N.M.4
van der Valk, M.5
Hooper, M.L.6
Berns, A.7
te Riele, H.8
-
37
-
-
0035835827
-
P107 and p130: Versatile proteins with interesting pockets
-
Classon M., Dyson N. p107 and p130: Versatile proteins with interesting pockets. Exp. Cell Res. 2001, 264:135-147.
-
(2001)
Exp. Cell Res.
, vol.264
, pp. 135-147
-
-
Classon, M.1
Dyson, N.2
-
38
-
-
0036037189
-
The retinoblastoma family: Twins or distant cousins?
-
(reviews 3012)
-
Claudio P.P., Tonini T., Giordano A. The retinoblastoma family: Twins or distant cousins?. Genome Biol. 2002, 3. (reviews 3012).
-
(2002)
Genome Biol.
, vol.3
-
-
Claudio, P.P.1
Tonini, T.2
Giordano, A.3
-
39
-
-
0015749593
-
A general theory of carcinogenesis
-
Comings D.E. A general theory of carcinogenesis. Proc. Natl. Acad. Sci. USA 1973, 70:3324-3328.
-
(1973)
Proc. Natl. Acad. Sci. USA
, vol.70
, pp. 3324-3328
-
-
Comings, D.E.1
-
40
-
-
0031019197
-
Cyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylation
-
Connell-Crowley L., Harper J.W., Goodrich D.W. Cyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylation. Mol. Biol. Cell 1997, 8:287-301.
-
(1997)
Mol. Biol. Cell
, vol.8
, pp. 287-301
-
-
Connell-Crowley, L.1
Harper, J.W.2
Goodrich, D.W.3
-
41
-
-
77954498022
-
Mitotic chromosome condensation mediated by the retinoblastoma protein is tumor-suppressive
-
Coschi C.H., Martens A.L., Ritchie K., Francis S.M., Chakrabarti S., Berube N.G., Dick F.A. Mitotic chromosome condensation mediated by the retinoblastoma protein is tumor-suppressive. Genes Dev. 2010, 24:1351-1363.
-
(2010)
Genes Dev.
, vol.24
, pp. 1351-1363
-
-
Coschi, C.H.1
Martens, A.L.2
Ritchie, K.3
Francis, S.M.4
Chakrabarti, S.5
Berube, N.G.6
Dick, F.A.7
-
42
-
-
42949129074
-
Many roads lead to oncogene-induced senescence
-
Courtois-Cox S., Jones S.L., Cichowski K. Many roads lead to oncogene-induced senescence. Oncogene 2008, 27:2801-2809.
-
(2008)
Oncogene
, vol.27
, pp. 2801-2809
-
-
Courtois-Cox, S.1
Jones, S.L.2
Cichowski, K.3
-
43
-
-
0034785586
-
Linking the Rb and polycomb pathways
-
Dahiya A., Wong S., Gonzalo S., Gavin M., Dean D.C. Linking the Rb and polycomb pathways. Mol. Cell 2001, 8:557-568.
-
(2001)
Mol. Cell
, vol.8
, pp. 557-568
-
-
Dahiya, A.1
Wong, S.2
Gonzalo, S.3
Gavin, M.4
Dean, D.C.5
-
44
-
-
6344245673
-
Disruption of the Rb-Raf-1 interaction inhibits tumor growth and angiogenesis
-
Dasgupta P., Sun J., Wang S., Fusaro G., Betts V., Padmanabhan J., Sebti S.M., Chellappan S.P. Disruption of the Rb-Raf-1 interaction inhibits tumor growth and angiogenesis. Mol. Cell. Biol. 2004, 24:9527-9541.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 9527-9541
-
-
Dasgupta, P.1
Sun, J.2
Wang, S.3
Fusaro, G.4
Betts, V.5
Padmanabhan, J.6
Sebti, S.M.7
Chellappan, S.P.8
-
45
-
-
59649101100
-
AMP-activated protein kinase phosphorylates retinoblastoma protein to control mammalian brain development
-
Dasgupta B., Milbrandt J., Dasgupta B., Milbrandt J. AMP-activated protein kinase phosphorylates retinoblastoma protein to control mammalian brain development. Dev. Cell 2009, 16:256-270.
-
(2009)
Dev. Cell
, vol.16
, pp. 256-270
-
-
Dasgupta, B.1
Milbrandt, J.2
Dasgupta, B.3
Milbrandt, J.4
-
46
-
-
0037113944
-
Rescue of embryonic epithelium reveals that the homozygous deletion of the retinoblastoma gene confers growth factor independence and immortality but does not influence epithelial differentiation or tissue morphogenesis
-
Day K.C., McCabe M.T., Zhao X., Wang Y., Davis J.N., Phillips J., Von Geldern M., Ried T., KuKuruga M.A., Cunha G.R., Hayward S.W., Day M.L. Rescue of embryonic epithelium reveals that the homozygous deletion of the retinoblastoma gene confers growth factor independence and immortality but does not influence epithelial differentiation or tissue morphogenesis. J. Biol. Chem. 2002, 277:44475-44484.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 44475-44484
-
-
Day, K.C.1
McCabe, M.T.2
Zhao, X.3
Wang, Y.4
Davis, J.N.5
Phillips, J.6
Von Geldern, M.7
Ried, T.8
KuKuruga, M.A.9
Cunha, G.R.10
Hayward, S.W.11
Day, M.L.12
-
47
-
-
0025808021
-
Cloning of cDNAs for cellular proteins that bind to the retinoblastoma gene product
-
Defeo-Jones D., Huang P.S., Jones R.E., Haskell K.M., Vuocolo G.A., Hanobik M.G., Huber H.E., Oliff A. Cloning of cDNAs for cellular proteins that bind to the retinoblastoma gene product. Nature 1991, 352:251-254.
-
(1991)
Nature
, vol.352
, pp. 251-254
-
-
Defeo-Jones, D.1
Huang, P.S.2
Jones, R.E.3
Haskell, K.M.4
Vuocolo, G.A.5
Hanobik, M.G.6
Huber, H.E.7
Oliff, A.8
-
48
-
-
33750909497
-
Rb at the interface between cell cycle and apoptotic decisions
-
Delston R.B., Harbour J.W., Delston R.B., Harbour J.W. Rb at the interface between cell cycle and apoptotic decisions. Curr. Mol. Med. 2006, 6:713-718.
-
(2006)
Curr. Mol. Med.
, vol.6
, pp. 713-718
-
-
Delston, R.B.1
Harbour, J.W.2
Delston, R.B.3
Harbour, J.W.4
-
49
-
-
0141927097
-
PRB contains an E2F1-specific binding domain that allows E2F1-induced apoptosis to be regulated separately from other E2F activities
-
Dick F.A., Dyson N. pRB contains an E2F1-specific binding domain that allows E2F1-induced apoptosis to be regulated separately from other E2F activities. Mol. Cell 2003, 12:639-649.
-
(2003)
Mol. Cell
, vol.12
, pp. 639-649
-
-
Dick, F.A.1
Dyson, N.2
-
50
-
-
0033970464
-
Suppression of the rbf null mutants by a de2f1 allele that lacks transactivation domain
-
Du W. Suppression of the rbf null mutants by a de2f1 allele that lacks transactivation domain. Development 2000, 127:367-379.
-
(2000)
Development
, vol.127
, pp. 367-379
-
-
Du, W.1
-
51
-
-
0033558346
-
The role of RBF in the introduction of G1 regulation during Drosophila embryogenesis
-
Du W., Dyson N. The role of RBF in the introduction of G1 regulation during Drosophila embryogenesis. EMBO J. 1999, 18:916-925.
-
(1999)
EMBO J.
, vol.18
, pp. 916-925
-
-
Du, W.1
Dyson, N.2
-
52
-
-
0028060515
-
The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest
-
Dunaief J.L., Strober B.E., Guha S., Khavari P.A., Alin K., Luban J., Begemann M., Crabtree G.R., Goff S.P. The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest. Cell 1994, 79:119-130.
-
(1994)
Cell
, vol.79
, pp. 119-130
-
-
Dunaief, J.L.1
Strober, B.E.2
Guha, S.3
Khavari, P.A.4
Alin, K.5
Luban, J.6
Begemann, M.7
Crabtree, G.R.8
Goff, S.P.9
-
53
-
-
0027251721
-
The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit
-
Durfee T., Becherer K., Chen P.L., Yeh S.H., Yang Y., Kilburn A.E., Lee W.H., Elledge S.J. The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit. Genes Dev. 1993, 7:555-569.
-
(1993)
Genes Dev.
, vol.7
, pp. 555-569
-
-
Durfee, T.1
Becherer, K.2
Chen, P.L.3
Yeh, S.H.4
Yang, Y.5
Kilburn, A.E.6
Lee, W.H.7
Elledge, S.J.8
-
54
-
-
0029044951
-
The transcription factor E2F is required for S phase during Drosophila embryogenesis
-
Duronio R.J., O'Farrell P.H., Xie J.E., Brook A., Dyson N. The transcription factor E2F is required for S phase during Drosophila embryogenesis. Genes Dev. 1995, 9:1445-1455.
-
(1995)
Genes Dev.
, vol.9
, pp. 1445-1455
-
-
Duronio, R.J.1
O'Farrell, P.H.2
Xie, J.E.3
Brook, A.4
Dyson, N.5
-
55
-
-
0027936686
-
Differential regulation of E2F transactivation by cyclin/cdk2 complexes
-
Dynlacht B.D., Flores O., Lees J.A., Harlow E. Differential regulation of E2F transactivation by cyclin/cdk2 complexes. Genes Dev. 1994, 8:1772-1786.
-
(1994)
Genes Dev.
, vol.8
, pp. 1772-1786
-
-
Dynlacht, B.D.1
Flores, O.2
Lees, J.A.3
Harlow, E.4
-
56
-
-
3042640434
-
Plant retinoblastoma homologues control nuclear proliferation in the female gametophyte
-
Ebel C., Mariconti L., Gruissem W. Plant retinoblastoma homologues control nuclear proliferation in the female gametophyte. Nature 2004, 429:776-780.
-
(2004)
Nature
, vol.429
, pp. 776-780
-
-
Ebel, C.1
Mariconti, L.2
Gruissem, W.3
-
57
-
-
0029015262
-
Promoter-dependent photocross-linking of the acidic transcriptional activator E2F-1 to the TATA-binding protein
-
Emili A., Ingles C.J. Promoter-dependent photocross-linking of the acidic transcriptional activator E2F-1 to the TATA-binding protein. J. Biol. Chem. 1995, 270:13674-13680.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 13674-13680
-
-
Emili, A.1
Ingles, C.J.2
-
58
-
-
0027380828
-
Characterization of the retinoblastoma binding proteins RBP1 and RBP2
-
Fattaey A.R., Helin K., Dembski M.S., Dyson N., Harlow E., Vuocolo G.A., Hanobik M.G., Haskell K.M., Oliff A., Defeo-Jones D., et al. Characterization of the retinoblastoma binding proteins RBP1 and RBP2. Oncogene 1993, 8:3149-3156.
-
(1993)
Oncogene
, vol.8
, pp. 3149-3156
-
-
Fattaey, A.R.1
Helin, K.2
Dembski, M.S.3
Dyson, N.4
Harlow, E.5
Vuocolo, G.A.6
Hanobik, M.G.7
Haskell, K.M.8
Oliff, A.9
Defeo-Jones, D.10
-
59
-
-
0037083918
-
Fzr-1 and lin-35/Rb function redundantly to control cell proliferation in C. elegans as revealed by a nonbiased synthetic screen
-
Fay D.S., Keenan S., Han M. fzr-1 and lin-35/Rb function redundantly to control cell proliferation in C. elegans as revealed by a nonbiased synthetic screen. Genes Dev. 2002, 16:503-517.
-
(2002)
Genes Dev.
, vol.16
, pp. 503-517
-
-
Fay, D.S.1
Keenan, S.2
Han, M.3
-
60
-
-
0037150653
-
Regulation of the different chromatin states of autosomes and X chromosomes in the germ line of C. elegans
-
Fong Y., Bender L., Wang W., Strome S. Regulation of the different chromatin states of autosomes and X chromosomes in the germ line of C. elegans. Science 2002, 296:2235-2238.
-
(2002)
Science
, vol.296
, pp. 2235-2238
-
-
Fong, Y.1
Bender, L.2
Wang, W.3
Strome, S.4
-
61
-
-
0022506980
-
A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma
-
Friend S.H., Bernards R., Rogelj S., Weinberg R.A., Rapaport J.M., Albert D.M., Dryja T.P. A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature 1986, 323:643-646.
-
(1986)
Nature
, vol.323
, pp. 643-646
-
-
Friend, S.H.1
Bernards, R.2
Rogelj, S.3
Weinberg, R.A.4
Rapaport, J.M.5
Albert, D.M.6
Dryja, T.P.7
-
62
-
-
2942722811
-
Molecular mechanisms of E2F-dependent activation and pRB-mediated repression
-
Frolov M.V., Dyson N.J. Molecular mechanisms of E2F-dependent activation and pRB-mediated repression. J. Cell Sci. 2004, 117:2173-2181.
-
(2004)
J. Cell Sci.
, vol.117
, pp. 2173-2181
-
-
Frolov, M.V.1
Dyson, N.J.2
-
63
-
-
33845687060
-
Loss of linker histone H1 in cellular senescence
-
Funayama R., Saito M., Tanobe H., Ishikawa F. Loss of linker histone H1 in cellular senescence. J. Cell Biol. 2006, 175:869-880.
-
(2006)
J. Cell Biol.
, vol.175
, pp. 869-880
-
-
Funayama, R.1
Saito, M.2
Tanobe, H.3
Ishikawa, F.4
-
64
-
-
0023222707
-
Structural evidence for the authenticity of the human retinoblastoma gene
-
Fung Y.K., Murphree A.L., T'Ang A., Qian J., Hinrichs S.H., Benedict W.F. Structural evidence for the authenticity of the human retinoblastoma gene. Science 1987, 236:1657-1661.
-
(1987)
Science
, vol.236
, pp. 1657-1661
-
-
Fung, Y.K.1
Murphree, A.L.2
T'Ang, A.3
Qian, J.4
Hinrichs, S.H.5
Benedict, W.F.6
-
65
-
-
33748039091
-
Involvement of RB gene family in tumor angiogenesis
-
Gabellini C., Del Bufalo D., Zupi G. Involvement of RB gene family in tumor angiogenesis. Oncogene 2006, 25:5326-5332.
-
(2006)
Oncogene
, vol.25
, pp. 5326-5332
-
-
Gabellini, C.1
Del Bufalo, D.2
Zupi, G.3
-
66
-
-
0038322038
-
The cyclin D1-dependent kinase associates with the pre-replication complex and modulates RB.MCM7 binding
-
Gladden A.B., Diehl J.A. The cyclin D1-dependent kinase associates with the pre-replication complex and modulates RB.MCM7 binding. J. Biol. Chem. 2003, 278:9754-9760.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 9754-9760
-
-
Gladden, A.B.1
Diehl, J.A.2
-
67
-
-
20244376464
-
Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin
-
Gonzalo S., Garcia-Cao M., Fraga M.F., Schotta G., Peters A.H., Cotter S.E., Eguia R., Dean D.C., Esteller M., Jenuwein T., Blasco M.A. Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin. Nat. Cell Biol. 2005, 7:420-428.
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 420-428
-
-
Gonzalo, S.1
Garcia-Cao, M.2
Fraga, M.F.3
Schotta, G.4
Peters, A.H.5
Cotter, S.E.6
Eguia, R.7
Dean, D.C.8
Esteller, M.9
Jenuwein, T.10
Blasco, M.A.11
-
68
-
-
0242380343
-
How the other half lives, the amino-terminal domain of the retinoblastoma tumor suppressor protein
-
Goodrich D.W. How the other half lives, the amino-terminal domain of the retinoblastoma tumor suppressor protein. J. Cell. Physiol. 2003, 197:169-180.
-
(2003)
J. Cell. Physiol.
, vol.197
, pp. 169-180
-
-
Goodrich, D.W.1
-
69
-
-
33748075785
-
The retinoblastoma tumor-suppressor gene, the exception that proves the rule
-
Goodrich D.W. The retinoblastoma tumor-suppressor gene, the exception that proves the rule. Oncogene 2006, 25:5233-5243.
-
(2006)
Oncogene
, vol.25
, pp. 5233-5243
-
-
Goodrich, D.W.1
-
70
-
-
0026058874
-
The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle
-
Goodrich D.W., Wang N.P., Qian Y.W., Lee E.Y., Lee W.H. The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle. Cell 1991, 67:293-302.
-
(1991)
Cell
, vol.67
, pp. 293-302
-
-
Goodrich, D.W.1
Wang, N.P.2
Qian, Y.W.3
Lee, E.Y.4
Lee, W.H.5
-
71
-
-
28444433734
-
Negative regulation of nuclear divisions in Caenorhabditis elegans by retinoblastoma and RNA interference-related genes
-
Grishok A., Sharp P.A. Negative regulation of nuclear divisions in Caenorhabditis elegans by retinoblastoma and RNA interference-related genes. Proc. Natl. Acad. Sci. USA 2005, 102:17360-17365.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 17360-17365
-
-
Grishok, A.1
Sharp, P.A.2
-
72
-
-
0027499060
-
Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation
-
Gu W., Schneider J.W., Condorelli G., Kaushal S., Mahdavi V., Nadal-Ginard B. Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation. Cell 1993, 72:309-324.
-
(1993)
Cell
, vol.72
, pp. 309-324
-
-
Gu, W.1
Schneider, J.W.2
Condorelli, G.3
Kaushal, S.4
Mahdavi, V.5
Nadal-Ginard, B.6
-
73
-
-
27744563251
-
Epidermal growth factor-induced rapid retinoblastoma phosphorylation at Ser780 and Ser795 is mediated by ERK1/2 in small intestine epithelial cells
-
Guo J., Sheng G., Warner B.W. Epidermal growth factor-induced rapid retinoblastoma phosphorylation at Ser780 and Ser795 is mediated by ERK1/2 in small intestine epithelial cells. J. Biol. Chem. 2005, 280:35992-35998.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 35992-35998
-
-
Guo, J.1
Sheng, G.2
Warner, B.W.3
-
74
-
-
58649106915
-
Retinoblastoma protein (pRb), but not p107 or p130, is required for maintenance of enterocyte quiescence and differentiation in small intestine
-
Guo J., Longshore S., Nair R., Warner B.W. Retinoblastoma protein (pRb), but not p107 or p130, is required for maintenance of enterocyte quiescence and differentiation in small intestine. J. Biol. Chem. 2009, 284:134-140.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 134-140
-
-
Guo, J.1
Longshore, S.2
Nair, R.3
Warner, B.W.4
-
76
-
-
57449095858
-
Impaired bone development and increased mesenchymal progenitor cells in calvaria of RB1-/- mice
-
Gutierrez G.M., Kong E., Sabbagh Y., Brown N.E., Lee J.S., Demay M.B., Thomas D.M., Hinds P.W. Impaired bone development and increased mesenchymal progenitor cells in calvaria of RB1-/- mice. Proc. Natl. Acad. Sci. USA 2008, 105:18402-18407.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 18402-18407
-
-
Gutierrez, G.M.1
Kong, E.2
Sabbagh, Y.3
Brown, N.E.4
Lee, J.S.5
Demay, M.B.6
Thomas, D.M.7
Hinds, P.W.8
-
77
-
-
0027520469
-
The retinoblastoma protein binds E2F residues required for activation in vivo and TBP binding in vitro
-
Hagemeier C., Cook A., Kouzarides T. The retinoblastoma protein binds E2F residues required for activation in vivo and TBP binding in vitro. Nucleic Acids Res. 1993, 21:4998-5004.
-
(1993)
Nucleic Acids Res.
, vol.21
, pp. 4998-5004
-
-
Hagemeier, C.1
Cook, A.2
Kouzarides, T.3
-
78
-
-
40449120350
-
An oncogene-induced DNA damage model for cancer development
-
Halazonetis T.D., Gorgoulis V.G., Bartek J. An oncogene-induced DNA damage model for cancer development. Science 2008, 319:1352-1355.
-
(2008)
Science
, vol.319
, pp. 1352-1355
-
-
Halazonetis, T.D.1
Gorgoulis, V.G.2
Bartek, J.3
-
79
-
-
61449249141
-
Balancing the decision of cell proliferation and cell fate
-
Hallstrom T.C., Nevins J.R., Hallstrom T.C., Nevins J.R. Balancing the decision of cell proliferation and cell fate. Cell Cycle 2009, 8:532-535.
-
(2009)
Cell Cycle
, vol.8
, pp. 532-535
-
-
Hallstrom, T.C.1
Nevins, J.R.2
Hallstrom, T.C.3
Nevins, J.R.4
-
80
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D., Weinberg R.A. The hallmarks of cancer. Cell 2000, 100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
81
-
-
33947177072
-
Developmentally regulated histone modifications in Drosophila follicle cells: Initiation of gene amplification is associated with histone H3 and H4 hyperacetylation and H1 phosphorylation
-
Hartl T., Boswell C., Orr-Weaver T.L., Bosco G. Developmentally regulated histone modifications in Drosophila follicle cells: Initiation of gene amplification is associated with histone H3 and H4 hyperacetylation and H1 phosphorylation. Chromosoma 2007, 116:197-214.
-
(2007)
Chromosoma
, vol.116
, pp. 197-214
-
-
Hartl, T.1
Boswell, C.2
Orr-Weaver, T.L.3
Bosco, G.4
-
82
-
-
35648942123
-
Crystal structure of the retinoblastoma protein N domain provides insight into tumor suppression, ligand interaction, and holoprotein architecture
-
Hassler M., Singh S., Yue W.W., Luczynski M., Lakbir R., Sanchez-Sanchez F., Bader T., Pearl L.H., Mittnacht S. Crystal structure of the retinoblastoma protein N domain provides insight into tumor suppression, ligand interaction, and holoprotein architecture. Mol. Cell 2007, 28:371-385.
-
(2007)
Mol. Cell
, vol.28
, pp. 371-385
-
-
Hassler, M.1
Singh, S.2
Yue, W.W.3
Luczynski, M.4
Lakbir, R.5
Sanchez-Sanchez, F.6
Bader, T.7
Pearl, L.H.8
Mittnacht, S.9
-
83
-
-
0026652346
-
A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F
-
Helin K., Lees J.A., Vidal M., Dyson N., Harlow E., Fattaey A. A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F. Cell 1992, 70:337-350.
-
(1992)
Cell
, vol.70
, pp. 337-350
-
-
Helin, K.1
Lees, J.A.2
Vidal, M.3
Dyson, N.4
Harlow, E.5
Fattaey, A.6
-
84
-
-
68049097008
-
Epigenetic dynamics of stem cells and cell lineage commitment: Digging Waddington's canal
-
Hemberger M., Dean W., Reik W. Epigenetic dynamics of stem cells and cell lineage commitment: Digging Waddington's canal. Nat. Rev. Mol. Cell Biol. 2009, 10:526-537.
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 526-537
-
-
Hemberger, M.1
Dean, W.2
Reik, W.3
-
85
-
-
4043093341
-
Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control
-
Hernando E., Nahle Z., Juan G., Diaz-Rodriguez E., Alaminos M., Hemann M., Michel L., Mittal V., Gerald W., Benezra R., Lowe S.W., Cordon-Cardo C. Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control. Nature 2004, 430:797-802.
-
(2004)
Nature
, vol.430
, pp. 797-802
-
-
Hernando, E.1
Nahle, Z.2
Juan, G.3
Diaz-Rodriguez, E.4
Alaminos, M.5
Hemann, M.6
Michel, L.7
Mittal, V.8
Gerald, W.9
Benezra, R.10
Lowe, S.W.11
Cordon-Cardo, C.12
-
86
-
-
0029909105
-
Increased histone H1 phosphorylation and relaxed chromatin structure in Rb-deficient fibroblasts
-
Herrera R.E., Chen F., Weinberg R.A. Increased histone H1 phosphorylation and relaxed chromatin structure in Rb-deficient fibroblasts. Proc. Natl. Acad. Sci. USA 1996, 93:11510-11515.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 11510-11515
-
-
Herrera, R.E.1
Chen, F.2
Weinberg, R.A.3
-
87
-
-
0026802989
-
Regulation of retinoblastoma protein functions by ectopic expression of human cyclins
-
Hinds P.W., Mittnacht S., Dulic V., Arnold A., Reed S.I., Weinberg R.A. Regulation of retinoblastoma protein functions by ectopic expression of human cyclins. Cell 1992, 70:993-1006.
-
(1992)
Cell
, vol.70
, pp. 993-1006
-
-
Hinds, P.W.1
Mittnacht, S.2
Dulic, V.3
Arnold, A.4
Reed, S.I.5
Weinberg, R.A.6
-
88
-
-
0037073753
-
Activation of the Rb/E2F1 pathway by the nonproliferative p38 MAPK during Fas (APO1/CD95)-mediated neuronal apoptosis
-
Hou S.T., Xie X., Baggley A., Park D.S., Chen G., Walker T. Activation of the Rb/E2F1 pathway by the nonproliferative p38 MAPK during Fas (APO1/CD95)-mediated neuronal apoptosis. J. Biol. Chem. 2002, 277:48764-48770.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 48764-48770
-
-
Hou, S.T.1
Xie, X.2
Baggley, A.3
Park, D.S.4
Chen, G.5
Walker, T.6
-
89
-
-
0024234852
-
Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells
-
Huang H.J., Yee J.K., Shew J.Y., Chen P.L., Bookstein R., Friedmann T., Lee E.Y., Lee W.H. Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells. Science 1988, 242:1563-1566.
-
(1988)
Science
, vol.242
, pp. 1563-1566
-
-
Huang, H.J.1
Yee, J.K.2
Shew, J.Y.3
Chen, P.L.4
Bookstein, R.5
Friedmann, T.6
Lee, E.Y.7
Lee, W.H.8
-
90
-
-
0034654105
-
E2f3 is critical for normal cellular proliferation
-
Humbert P.O., Verona R., Trimarchi J.M., Rogers C., Dandapani S., Lees J.A. E2f3 is critical for normal cellular proliferation. Genes Dev. 2000, 14:690-703.
-
(2000)
Genes Dev.
, vol.14
, pp. 690-703
-
-
Humbert, P.O.1
Verona, R.2
Trimarchi, J.M.3
Rogers, C.4
Dandapani, S.5
Lees, J.A.6
-
91
-
-
0028303223
-
The helix-loop-helix protein Id-2 enhances cell proliferation and binds to the retinoblastoma protein
-
Iavarone A., Garg P., Lasorella A., Hsu J., Israel M.A. The helix-loop-helix protein Id-2 enhances cell proliferation and binds to the retinoblastoma protein. Genes Dev. 1994, 8:1270-1284.
-
(1994)
Genes Dev.
, vol.8
, pp. 1270-1284
-
-
Iavarone, A.1
Garg, P.2
Lasorella, A.3
Hsu, J.4
Israel, M.A.5
-
92
-
-
11144248047
-
Retinoblastoma promotes definitive erythropoiesis by repressing Id2 in fetal liver macrophages
-
Iavarone A., King E.R., Dai X.M., Leone G., Stanley E.R., Lasorella A. Retinoblastoma promotes definitive erythropoiesis by repressing Id2 in fetal liver macrophages. Nature 2004, 432:1040-1045.
-
(2004)
Nature
, vol.432
, pp. 1040-1045
-
-
Iavarone, A.1
King, E.R.2
Dai, X.M.3
Leone, G.4
Stanley, E.R.5
Lasorella, A.6
-
93
-
-
33947540326
-
The female gametophyte and the endosperm control cell proliferation and differentiation of the seed coat in Arabidopsis
-
Ingouff M., Jullien P.E., Berger F. The female gametophyte and the endosperm control cell proliferation and differentiation of the seed coat in Arabidopsis. Plant Cell 2006, 18:3491-3501.
-
(2006)
Plant Cell
, vol.18
, pp. 3491-3501
-
-
Ingouff, M.1
Jullien, P.E.2
Berger, F.3
-
94
-
-
34247199852
-
Phosphorylation of pRB at Ser612 by Chk1/2 leads to a complex between pRB and E2F-1 after DNA damage
-
Inoue Y., Kitagawa M., Taya Y. Phosphorylation of pRB at Ser612 by Chk1/2 leads to a complex between pRB and E2F-1 after DNA damage. EMBO J. 2007, 26:2083-2093.
-
(2007)
EMBO J.
, vol.26
, pp. 2083-2093
-
-
Inoue, Y.1
Kitagawa, M.2
Taya, Y.3
-
95
-
-
33750220492
-
RB acute loss induces centrosome amplification and aneuploidy in murine primary fibroblasts
-
Iovino F., Lentini L., Amato A., Di Leonardo A. RB acute loss induces centrosome amplification and aneuploidy in murine primary fibroblasts. Mol. Cancer 2006, 5:38.
-
(2006)
Mol. Cancer
, vol.5
, pp. 38
-
-
Iovino, F.1
Lentini, L.2
Amato, A.3
Di Leonardo, A.4
-
96
-
-
33646250688
-
The retinoblastoma protein regulates pericentric heterochromatin
-
Isaac C.E., Francis S.M., Martens A.L., Julian L.M., Seifried L.A., Erdmann N., Binne U.K., Harrington L., Sicinski P., Berube N.G., Dyson N.J., Dick F.A. The retinoblastoma protein regulates pericentric heterochromatin. Mol. Cell. Biol. 2006, 26:3659-3671.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 3659-3671
-
-
Isaac, C.E.1
Francis, S.M.2
Martens, A.L.3
Julian, L.M.4
Seifried, L.A.5
Erdmann, N.6
Binne, U.K.7
Harrington, L.8
Sicinski, P.9
Berube, N.G.10
Dyson, N.J.11
Dick, F.A.12
-
97
-
-
0034949169
-
Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis
-
Ishida S., Huang E., Zuzan H., Spang R., Leone G., West M., Nevins J.R. Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis. Mol. Cell. Biol. 2001, 21:4684-4699.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 4684-4699
-
-
Ishida, S.1
Huang, E.2
Zuzan, H.3
Spang, R.4
Leone, G.5
West, M.6
Nevins, J.R.7
-
98
-
-
33947302685
-
The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases
-
Iwase S., Lan F., Bayliss P., de la Torre-Ubieta L., Huarte M., Qi H.H., Whetstine J.R., Bonni A., Roberts T.M., Shi Y. The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases. Cell 2007, 128:1077-1088.
-
(2007)
Cell
, vol.128
, pp. 1077-1088
-
-
Iwase, S.1
Lan, F.2
Bayliss, P.3
de la Torre-Ubieta, L.4
Huarte, M.5
Qi, H.H.6
Whetstine, J.R.7
Bonni, A.8
Roberts, T.M.9
Shi, Y.10
-
99
-
-
0026702996
-
Effects of an Rb mutation in the mouse
-
Jacks T., Fazeli A., Schmitt E.M., Bronson R.T., Goodell M.A., Weinberg R.A. Effects of an Rb mutation in the mouse. Nature 1992, 359:295-300.
-
(1992)
Nature
, vol.359
, pp. 295-300
-
-
Jacks, T.1
Fazeli, A.2
Schmitt, E.M.3
Bronson, R.T.4
Goodell, M.A.5
Weinberg, R.A.6
-
100
-
-
75649109727
-
Combinations of genetic mutations in the adult neural stem cell compartment determine brain tumour phenotypes
-
Jacques T.S., Swales A., Brzozowski M.J., Henriquez N.V., Linehan J.M., Mirzadeh Z., Malley C.O., Naumann H., Alvarez-Buylla A., Brandner S. Combinations of genetic mutations in the adult neural stem cell compartment determine brain tumour phenotypes. Embo J. 2010, 29:222-235.
-
(2010)
Embo J.
, vol.29
, pp. 222-235
-
-
Jacques, T.S.1
Swales, A.2
Brzozowski, M.J.3
Henriquez, N.V.4
Linehan, J.M.5
Mirzadeh, Z.6
Malley, C.O.7
Naumann, H.8
Alvarez-Buylla, A.9
Brandner, S.10
-
101
-
-
4944252223
-
An Rb-Skp2-p27 pathway mediates acute cell cycle inhibition by Rb and is retained in a partial-penetrance Rb mutant
-
Ji P., Jiang H., Rekhtman K., Bloom J., Ichetovkin M., Pagano M., Zhu L. An Rb-Skp2-p27 pathway mediates acute cell cycle inhibition by Rb and is retained in a partial-penetrance Rb mutant. Mol. Cell 2004, 16:47-58.
-
(2004)
Mol. Cell
, vol.16
, pp. 47-58
-
-
Ji, P.1
Jiang, H.2
Rekhtman, K.3
Bloom, J.4
Ichetovkin, M.5
Pagano, M.6
Zhu, L.7
-
102
-
-
0037033802
-
Activation of retinoblastoma protein in mammary gland leads to ductal growth suppression, precocious differentiation, and adenocarcinoma
-
Jiang Z., Zacksenhaus E. Activation of retinoblastoma protein in mammary gland leads to ductal growth suppression, precocious differentiation, and adenocarcinoma. J. Cell Biol. 2002, 156:185-198.
-
(2002)
J. Cell Biol.
, vol.156
, pp. 185-198
-
-
Jiang, Z.1
Zacksenhaus, E.2
-
103
-
-
34047249978
-
Neuronal differentiation and synaptogenesis in retinoblastoma
-
Johnson D.A., Zhang J., Frase S., Wilson M., Rodriguez-Galindo C., Dyer M.A. Neuronal differentiation and synaptogenesis in retinoblastoma. Cancer Res. 2007, 67:2701-2711.
-
(2007)
Cancer Res.
, vol.67
, pp. 2701-2711
-
-
Johnson, D.A.1
Zhang, J.2
Frase, S.3
Wilson, M.4
Rodriguez-Galindo, C.5
Dyer, M.A.6
-
104
-
-
67649981723
-
Direct binding of pRb/E2F-2 to GATA-1 regulates maturation and terminal cell division during erythropoiesis
-
Kadri Z., Shimizu R., Ohneda O., Maouche-Chretien L., Gisselbrecht S., Yamamoto M., Romeo P.H., Leboulch P., Chretien S. Direct binding of pRb/E2F-2 to GATA-1 regulates maturation and terminal cell division during erythropoiesis. PLoS Biol. 2009, 7:e1000123.
-
(2009)
PLoS Biol.
, vol.7
-
-
Kadri, Z.1
Shimizu, R.2
Ohneda, O.3
Maouche-Chretien, L.4
Gisselbrecht, S.5
Yamamoto, M.6
Romeo, P.H.7
Leboulch, P.8
Chretien, S.9
-
105
-
-
0026766083
-
Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties
-
Kaelin W.G., Krek W., Sellers W.R., DeCaprio J.A., Ajchenbaum F., Fuchs C.S., Chittenden T., Li Y., Farnham P.J., Blanar M.A., et al. Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties. Cell 1992, 70:351-364.
-
(1992)
Cell
, vol.70
, pp. 351-364
-
-
Kaelin, W.G.1
Krek, W.2
Sellers, W.R.3
DeCaprio, J.A.4
Ajchenbaum, F.5
Fuchs, C.S.6
Chittenden, T.7
Li, Y.8
Farnham, P.J.9
Blanar, M.A.10
-
106
-
-
0032739015
-
Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD
-
Ketting R.F., Haverkamp T.H., van Luenen H.G., Plasterk R.H. Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD. Cell 1999, 99:133-141.
-
(1999)
Cell
, vol.99
, pp. 133-141
-
-
Ketting, R.F.1
Haverkamp, T.H.2
van Luenen, H.G.3
Plasterk, R.H.4
-
107
-
-
0030996584
-
Structural similarity between the pocket region of retinoblastoma tumour suppressor and the cyclin-box
-
Kim H.Y., Cho Y. Structural similarity between the pocket region of retinoblastoma tumour suppressor and the cyclin-box. Nat. Struct. Biol. 1997, 4:390-395.
-
(1997)
Nat. Struct. Biol.
, vol.4
, pp. 390-395
-
-
Kim, H.Y.1
Cho, Y.2
-
108
-
-
0026719682
-
Retinoblastoma gene product activates expression of the human TGF-beta 2 gene through transcription factor ATF-2
-
Kim S.J., Wagner S., Liu F., O'Reilly M.A., Robbins P.D., Green M.R. Retinoblastoma gene product activates expression of the human TGF-beta 2 gene through transcription factor ATF-2. Nature 1992, 358:331-334.
-
(1992)
Nature
, vol.358
, pp. 331-334
-
-
Kim, S.J.1
Wagner, S.2
Liu, F.3
O'Reilly, M.A.4
Robbins, P.D.5
Green, M.R.6
-
109
-
-
0035863048
-
Structural basis for the inactivation of retinoblastoma tumor suppressor by SV40 large T antigen
-
Kim H.Y., Ahn B.Y., Cho Y. Structural basis for the inactivation of retinoblastoma tumor suppressor by SV40 large T antigen. EMBO J. 2001, 20:295-304.
-
(2001)
EMBO J.
, vol.20
, pp. 295-304
-
-
Kim, H.Y.1
Ahn, B.Y.2
Cho, Y.3
-
110
-
-
34247563433
-
Transcriptome profiling of the C. elegans Rb ortholog reveals diverse developmental roles
-
Kirienko N.V., Fay D.S. Transcriptome profiling of the C. elegans Rb ortholog reveals diverse developmental roles. Dev. Biol. 2007, 305:674-684.
-
(2007)
Dev. Biol.
, vol.305
, pp. 674-684
-
-
Kirienko, N.V.1
Fay, D.S.2
-
111
-
-
33847401344
-
The retinoblastoma binding protein RBP2 is an H3K4 demethylase
-
Klose R.J., Yan Q., Tothova Z., Yamane K., Erdjument-Bromage H., Tempst P., Gilliland D.G., Zhang Y., Kaelin W.G. The retinoblastoma binding protein RBP2 is an H3K4 demethylase. Cell 2007, 128:889-900.
-
(2007)
Cell
, vol.128
, pp. 889-900
-
-
Klose, R.J.1
Yan, Q.2
Tothova, Z.3
Yamane, K.4
Erdjument-Bromage, H.5
Tempst, P.6
Gilliland, D.G.7
Zhang, Y.8
Kaelin, W.G.9
-
112
-
-
0029924241
-
Differential regulation of retinoblastoma protein function by specific Cdk phosphorylation sites
-
Knudsen E.S., Wang J.Y.J. Differential regulation of retinoblastoma protein function by specific Cdk phosphorylation sites. J. Biol. Chem. 1996, 271:8313-8320.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 8313-8320
-
-
Knudsen, E.S.1
Wang, J.Y.J.2
-
113
-
-
0030849455
-
Dual mechanisms for the inhibition of E2F binding to RB by cyclin-dependent kinase-mediated RB phosphorylation
-
Knudsen E.S., Wang J.Y.J. Dual mechanisms for the inhibition of E2F binding to RB by cyclin-dependent kinase-mediated RB phosphorylation. Mol. Cell. Biol. 1997, 17:5771-5783.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 5771-5783
-
-
Knudsen, E.S.1
Wang, J.Y.J.2
-
114
-
-
33750906287
-
Role of the retinoblastoma tumor suppressor in the maintenance of genome integrity
-
Knudsen E.S., Sexton C.R., Mayhew C.N., Knudsen E.S., Sexton C.R., Mayhew C.N. Role of the retinoblastoma tumor suppressor in the maintenance of genome integrity. Curr. Mol. Med. 2006, 6:749-757.
-
(2006)
Curr. Mol. Med.
, vol.6
, pp. 749-757
-
-
Knudsen, E.S.1
Sexton, C.R.2
Mayhew, C.N.3
Knudsen, E.S.4
Sexton, C.R.5
Mayhew, C.N.6
-
115
-
-
0015043748
-
Mutation and cancer: Statistical study of retinoblastoma
-
Knudson A.G. Mutation and cancer: Statistical study of retinoblastoma. Proc. Natl. Acad. Sci. USA 1971, 68:820-823.
-
(1971)
Proc. Natl. Acad. Sci. USA
, vol.68
, pp. 820-823
-
-
Knudson, A.G.1
-
116
-
-
24344442345
-
E2F-Rb complexes regulating transcription of genes important for differentiation and development
-
Korenjak M., Brehm A., Korenjak M., Brehm A. E2F-Rb complexes regulating transcription of genes important for differentiation and development. Curr. Opin. Genet. Dev. 2005, 15:520-527.
-
(2005)
Curr. Opin. Genet. Dev.
, vol.15
, pp. 520-527
-
-
Korenjak, M.1
Brehm, A.2
Korenjak, M.3
Brehm, A.4
-
117
-
-
55749107458
-
Loss of Rb1 in the gastrointestinal tract of Apc1638N mice promotes tumors of the cecum and proximal colon
-
Kucherlapati M.H., Yang K., Fan K., Kuraguchi M., Sonkin D., Rosulek A., Lipkin M., Bronson R.T., Aronow B.J., Kucherlapati R. Loss of Rb1 in the gastrointestinal tract of Apc1638N mice promotes tumors of the cecum and proximal colon. Proc. Natl. Acad. Sci. USA 2008, 105:15493-15498.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 15493-15498
-
-
Kucherlapati, M.H.1
Yang, K.2
Fan, K.3
Kuraguchi, M.4
Sonkin, D.5
Rosulek, A.6
Lipkin, M.7
Bronson, R.T.8
Aronow, B.J.9
Kucherlapati, R.10
-
118
-
-
0021262921
-
Retinoblastoma-origin from a primitive neuroectodermal cell?
-
Kyritsis A.P., Tsokos M., Triche T.J., Chader G.J. Retinoblastoma-origin from a primitive neuroectodermal cell?. Nature 1984, 307:471-473.
-
(1984)
Nature
, vol.307
, pp. 471-473
-
-
Kyritsis, A.P.1
Tsokos, M.2
Triche, T.J.3
Chader, G.J.4
-
119
-
-
0032849352
-
RBP1 recruits both histone deacetylase-dependent and -independent repression activities to retinoblastoma family proteins
-
Lai A., Lee J.M., Yang W.M., DeCaprio J.A., Kaelin W.G., Seto E., Branton P.E. RBP1 recruits both histone deacetylase-dependent and -independent repression activities to retinoblastoma family proteins. Mol. Cell. Biol. 1999, 19:6632-6641.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 6632-6641
-
-
Lai, A.1
Lee, J.M.2
Yang, W.M.3
DeCaprio, J.A.4
Kaelin, W.G.5
Seto, E.6
Branton, P.E.7
-
120
-
-
0035076249
-
RBP1 recruits the mSIN3-histone deacetylase complex to the pocket of retinoblastoma tumor suppressor family proteins found in limited discrete regions of the nucleus at growth arrest
-
Lai A., Kennedy B.K., Barbie D.A., Bertos N.R., Yang X.J., Theberge M.C., Tsai S.C., Seto E., Zhang Y., Kuzmichev A., Lane W.S., Reinberg D., et al. RBP1 recruits the mSIN3-histone deacetylase complex to the pocket of retinoblastoma tumor suppressor family proteins found in limited discrete regions of the nucleus at growth arrest. Mol. Cell. Biol. 2001, 21:2918-2932.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 2918-2932
-
-
Lai, A.1
Kennedy, B.K.2
Barbie, D.A.3
Bertos, N.R.4
Yang, X.J.5
Theberge, M.C.6
Tsai, S.C.7
Seto, E.8
Zhang, Y.9
Kuzmichev, A.10
Lane, W.S.11
Reinberg, D.12
-
121
-
-
0037418266
-
The role of E2F4 in adipogenesis is independent of its cell cycle regulatory activity
-
Landsberg R.L., Sero J.E., Danielian P.S., Yuan T.L., Lee E.Y., Lees J.A. The role of E2F4 in adipogenesis is independent of its cell cycle regulatory activity. Proc. Natl. Acad. Sci. USA 2003, 100:2456-2461.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 2456-2461
-
-
Landsberg, R.L.1
Sero, J.E.2
Danielian, P.S.3
Yuan, T.L.4
Lee, E.Y.5
Lees, J.A.6
-
122
-
-
0035979992
-
E2F transcriptional activation requires TRRAP and GCN5 cofactors
-
Lang S.E., McMahon S.B., Cole M.D., Hearing P. E2F transcriptional activation requires TRRAP and GCN5 cofactors. J. Biol. Chem. 2001, 276:32627-32634.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 32627-32634
-
-
Lang, S.E.1
McMahon, S.B.2
Cole, M.D.3
Hearing, P.4
-
123
-
-
33750590095
-
Inactivation of the p53 pathway in retinoblastoma
-
Laurie N.A., Donovan S.L., Shih C.-S., Zhang J., Mills N., Fuller C., Teunisse A., Lam S., Ramos Y., Mohan A., Johnson D., Wilson M., et al. Inactivation of the p53 pathway in retinoblastoma. Nature 2006, 444:61-66.
-
(2006)
Nature
, vol.444
, pp. 61-66
-
-
Laurie, N.A.1
Donovan, S.L.2
Shih, C.-S.3
Zhang, J.4
Mills, N.5
Fuller, C.6
Teunisse, A.7
Lam, S.8
Ramos, Y.9
Mohan, A.10
Johnson, D.11
Wilson, M.12
-
124
-
-
33746035661
-
P14ARF promotes RB accumulation through inhibition of its Tip60-dependent acetylation
-
Leduc C., Claverie P., Eymin B., Col E., Khochbin S., Brambilla E., Gazzeri S. p14ARF promotes RB accumulation through inhibition of its Tip60-dependent acetylation. Oncogene 2006, 25:4147-4154.
-
(2006)
Oncogene
, vol.25
, pp. 4147-4154
-
-
Leduc, C.1
Claverie, P.2
Eymin, B.3
Col, E.4
Khochbin, S.5
Brambilla, E.6
Gazzeri, S.7
-
125
-
-
0037115601
-
Structural basis for the recognition of the E2F transactivation domain by the retinoblastoma tumor suppressor
-
Lee C.C.J.H. Structural basis for the recognition of the E2F transactivation domain by the retinoblastoma tumor suppressor. Genes Dev. 2002, 16:3199-3212.
-
(2002)
Genes Dev.
, vol.16
, pp. 3199-3212
-
-
Lee, C.C.J.H.1
-
126
-
-
0023106062
-
Human retinoblastoma susceptibility gene: Cloning, identification, and sequence
-
Lee W.H., Bookstein R., Hong F., Young L.J., Shew J.Y., Lee E.Y.H.P. Human retinoblastoma susceptibility gene: Cloning, identification, and sequence. Science 1987, 235:1394-1399.
-
(1987)
Science
, vol.235
, pp. 1394-1399
-
-
Lee, W.H.1
Bookstein, R.2
Hong, F.3
Young, L.J.4
Shew, J.Y.5
Lee, E.Y.H.P.6
-
127
-
-
0026744563
-
Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis
-
Lee E.Y., Chang C.Y., Hu N., Wang Y.C., Lai C.C., Herrup K., Lee W.H. Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis. Nature 1992, 359:288-294.
-
(1992)
Nature
, vol.359
, pp. 288-294
-
-
Lee, E.Y.1
Chang, C.Y.2
Hu, N.3
Wang, Y.C.4
Lai, C.C.5
Herrup, K.6
Lee, W.H.7
-
128
-
-
2642601106
-
Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7
-
Lee J.O., Russo A.A., Pavletich N.P. Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7. Nature 1998, 391:859-865.
-
(1998)
Nature
, vol.391
, pp. 859-865
-
-
Lee, J.O.1
Russo, A.A.2
Pavletich, N.P.3
-
129
-
-
0001445037
-
E2F4 loss suppresses tumorigenesis in Rb mutant mice
-
Lee E.Y., Cam H., Ziebold U., Rayman J.B., Lees J.A., Dynlacht B.D. E2F4 loss suppresses tumorigenesis in Rb mutant mice. Cancer Cell 2002, 2:463-472.
-
(2002)
Cancer Cell
, vol.2
, pp. 463-472
-
-
Lee, E.Y.1
Cam, H.2
Ziebold, U.3
Rayman, J.B.4
Lees, J.A.5
Dynlacht, B.D.6
-
130
-
-
0036118561
-
Reversal of growth suppression by p107 via direct phosphorylation by cyclin D1/cyclin-dependent kinase 4
-
Leng X., Noble M., Adams P.D., Qin J., Harper J.W. Reversal of growth suppression by p107 via direct phosphorylation by cyclin D1/cyclin-dependent kinase 4. Mol. Cell. Biol. 2002, 22:2242-2254.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 2242-2254
-
-
Leng, X.1
Noble, M.2
Adams, P.D.3
Qin, J.4
Harper, J.W.5
-
131
-
-
0035914347
-
MRG15 activates the B-myb promoter through formation of a nuclear complex with the retinoblastoma protein and the novel protein PAM14
-
Leung J.K., Berube N., Venable S., Ahmed S., Timchenko N., Pereira-Smith O.M. MRG15 activates the B-myb promoter through formation of a nuclear complex with the retinoblastoma protein and the novel protein PAM14. J. Biol. Chem. 2001, 276:39171-39178.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 39171-39178
-
-
Leung, J.K.1
Berube, N.2
Venable, S.3
Ahmed, S.4
Timchenko, N.5
Pereira-Smith, O.M.6
-
132
-
-
35948959373
-
Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor
-
Liu X., Marmorstein R. Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor. Genes Dev. 2007, 21:2711-2716.
-
(2007)
Genes Dev.
, vol.21
, pp. 2711-2716
-
-
Liu, X.1
Marmorstein, R.2
-
133
-
-
0842281494
-
New roles for the RB tumor suppressor protein
-
Liu H., Dibling B., Spike B., Dirlam A., Macleod K. New roles for the RB tumor suppressor protein. Curr. Opin. Genet. Dev. 2004, 14:55-64.
-
(2004)
Curr. Opin. Genet. Dev.
, vol.14
, pp. 55-64
-
-
Liu, H.1
Dibling, B.2
Spike, B.3
Dirlam, A.4
Macleod, K.5
-
134
-
-
74149083175
-
PRb, a local chromatin organizer with global possibilities
-
Longworth M.S., Dyson N.J. pRb, a local chromatin organizer with global possibilities. Chromosoma 2009, 119:1-11.
-
(2009)
Chromosoma
, vol.119
, pp. 1-11
-
-
Longworth, M.S.1
Dyson, N.J.2
-
135
-
-
42149095961
-
RBF1 promotes chromatin condensation through a conserved interaction with the Condensin II protein dCAP-D3
-
Longworth M.S., Herr A., Ji J.Y., Dyson N.J. RBF1 promotes chromatin condensation through a conserved interaction with the Condensin II protein dCAP-D3. Genes Dev. 2008, 22:1011-1024.
-
(2008)
Genes Dev.
, vol.22
, pp. 1011-1024
-
-
Longworth, M.S.1
Herr, A.2
Ji, J.Y.3
Dyson, N.J.4
-
136
-
-
0032553424
-
Differential regulation of androgen and glucocorticoid receptors by retinoblastoma protein
-
Lu J., Danielsen M. Differential regulation of androgen and glucocorticoid receptors by retinoblastoma protein. J. Biol. Chem. 1998, 273:31528-31533.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 31528-31533
-
-
Lu, J.1
Danielsen, M.2
-
137
-
-
0027455644
-
Specific enzymatic dephosphorylation of the retinoblastoma protein
-
Ludlow J.W., Glendening C.L., Livingston D.M., DeCaprio J.A. Specific enzymatic dephosphorylation of the retinoblastoma protein. Mol. Cell. Biol. 1993, 13:367-372.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 367-372
-
-
Ludlow, J.W.1
Glendening, C.L.2
Livingston, D.M.3
DeCaprio, J.A.4
-
138
-
-
0032549001
-
Rb interacts with histone deacetylase to repress transcription
-
Luo R.X., Postigo A.A., Dean D.C. Rb interacts with histone deacetylase to repress transcription. Cell 1998, 92:463-473.
-
(1998)
Cell
, vol.92
, pp. 463-473
-
-
Luo, R.X.1
Postigo, A.A.2
Dean, D.C.3
-
139
-
-
0034460363
-
A novel Rb- and p300-binding protein inhibits transactivation by MyoD
-
MacLellan W.R., Xiao G., Abdellatif M., Schneider M.D. A novel Rb- and p300-binding protein inhibits transactivation by MyoD. Mol. Cell. Biol. 2000, 20:8903-8915.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 8903-8915
-
-
MacLellan, W.R.1
Xiao, G.2
Abdellatif, M.3
Schneider, M.D.4
-
140
-
-
52549128786
-
The role of the RB tumour suppressor pathway in oxidative stress responses in the haematopoietic system
-
Macleod K.F. The role of the RB tumour suppressor pathway in oxidative stress responses in the haematopoietic system. Nat. Rev. Cancer 2008, 8:769-781.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 769-781
-
-
Macleod, K.F.1
-
141
-
-
2942512013
-
Cell type-specific effects of Rb deletion in the murine retina
-
MacPherson D., Sage J., Kim T., Ho D., McLaughlin M.E., Jacks T. Cell type-specific effects of Rb deletion in the murine retina. Genes Dev. 2004, 18:1681-1694.
-
(2004)
Genes Dev.
, vol.18
, pp. 1681-1694
-
-
MacPherson, D.1
Sage, J.2
Kim, T.3
Ho, D.4
McLaughlin, M.E.5
Jacks, T.6
-
142
-
-
4344577121
-
Conditional deletion of Rb causes early stage prostate cancer
-
Maddison L.A., Sutherland B.W., Barrios R.J., Greenberg N.M. Conditional deletion of Rb causes early stage prostate cancer. Cancer Res. 2004, 64:6018-6025.
-
(2004)
Cancer Res.
, vol.64
, pp. 6018-6025
-
-
Maddison, L.A.1
Sutherland, B.W.2
Barrios, R.J.3
Greenberg, N.M.4
-
143
-
-
77649208749
-
Cancer stem cells: A reality, a myth, a fuzzy concept or a misnomer? An analysis
-
Maenhaut C., Dumont J.E., Roger P.P., van Staveren W.C. Cancer stem cells: A reality, a myth, a fuzzy concept or a misnomer? An analysis. Carcinogenesis 2010, 31:149-158.
-
(2010)
Carcinogenesis
, vol.31
, pp. 149-158
-
-
Maenhaut, C.1
Dumont, J.E.2
Roger, P.P.3
van Staveren, W.C.4
-
144
-
-
0032484904
-
Retinoblastoma protein represses transcription by recruiting a histone deacetylase
-
Magnaghi-Jaulin L., Groisman R., Naguibneva I., Robin P., Lorain S., LeVillain J.P., Troalen F., Trouche D., Harel-Bellan A. Retinoblastoma protein represses transcription by recruiting a histone deacetylase. Nature 1998, 391:601-605.
-
(1998)
Nature
, vol.391
, pp. 601-605
-
-
Magnaghi-Jaulin, L.1
Groisman, R.2
Naguibneva, I.3
Robin, P.4
Lorain, S.5
LeVillain, J.P.6
Troalen, F.7
Trouche, D.8
Harel-Bellan, A.9
-
145
-
-
0035754080
-
To cycle or not to cycle: A critical decision in cancer
-
Malumbres M., Barbacid M. To cycle or not to cycle: A critical decision in cancer. Nat. Rev. Cancer 2001, 1:222-231.
-
(2001)
Nat. Rev. Cancer
, vol.1
, pp. 222-231
-
-
Malumbres, M.1
Barbacid, M.2
-
146
-
-
77954522274
-
Loss of pRB causes centromere dysfunction and chromosomal instability
-
Manning A.L., Longworth M.S., Dyson N.J. Loss of pRB causes centromere dysfunction and chromosomal instability. Genes Dev. 2010, 24:1364-1376.
-
(2010)
Genes Dev.
, vol.24
, pp. 1364-1376
-
-
Manning, A.L.1
Longworth, M.S.2
Dyson, N.J.3
-
147
-
-
58049202910
-
Risk of second malignancies in survivors of retinoblastoma: More than 40 years of follow-up
-
Marees T., Moll A.C., Imhof S.M., de Boer M.R., Ringens P.J., van Leeuwen F.E. Risk of second malignancies in survivors of retinoblastoma: More than 40 years of follow-up. J. Natl. Cancer Inst. 2008, 100:1771-1779.
-
(2008)
J. Natl. Cancer Inst.
, vol.100
, pp. 1771-1779
-
-
Marees, T.1
Moll, A.C.2
Imhof, S.M.3
de Boer, M.R.4
Ringens, P.J.5
van Leeuwen, F.E.6
-
148
-
-
0042977676
-
Rb and p107 are required for normal cerebellar development and granule cell survival but not for Purkinje cell persistence
-
Marino S., Hoogervoorst D., Brandner S., Berns A. Rb and p107 are required for normal cerebellar development and granule cell survival but not for Purkinje cell persistence. Development 2003, 130:3359-3368.
-
(2003)
Development
, vol.130
, pp. 3359-3368
-
-
Marino, S.1
Hoogervoorst, D.2
Brandner, S.3
Berns, A.4
-
149
-
-
33645830066
-
DNA-damage-responsive acetylation of pRb regulates binding to E2F-1
-
Markham D., Munro S., Soloway J., O'Connor D.P., La Thangue N.B. DNA-damage-responsive acetylation of pRb regulates binding to E2F-1. EMBO Rep. 2006, 7:192-198.
-
(2006)
EMBO Rep.
, vol.7
, pp. 192-198
-
-
Markham, D.1
Munro, S.2
Soloway, J.3
O'Connor, D.P.4
La Thangue, N.B.5
-
150
-
-
38849167565
-
Spontaneous squamous cell carcinoma induced by the somatic inactivation of retinoblastoma and Trp53 tumor suppressors
-
Martinez-Cruz A.B., Santos M., Lara M.F., Segrelles C., Ruiz S., Moral M., Lorz C., Garcia-Escudero R., Paramio J.M. Spontaneous squamous cell carcinoma induced by the somatic inactivation of retinoblastoma and Trp53 tumor suppressors. Cancer Res. 2008, 68:683-692.
-
(2008)
Cancer Res.
, vol.68
, pp. 683-692
-
-
Martinez-Cruz, A.B.1
Santos, M.2
Lara, M.F.3
Segrelles, C.4
Ruiz, S.5
Moral, M.6
Lorz, C.7
Garcia-Escudero, R.8
Paramio, J.M.9
-
151
-
-
34249781210
-
Unique requirement for Rb/E2F3 in neuronal migration: Evidence for cell cycle-independent functions
-
McClellan K.A., Ruzhynsky V.A., Douda D.N., Vanderluit J.L., Ferguson K.L., Chen D., Bremner R., Park D.S., Leone G., Slack R.S. Unique requirement for Rb/E2F3 in neuronal migration: Evidence for cell cycle-independent functions. Mol. Cell. Biol. 2007, 27:4825-4843.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 4825-4843
-
-
McClellan, K.A.1
Ruzhynsky, V.A.2
Douda, D.N.3
Vanderluit, J.L.4
Ferguson, K.L.5
Chen, D.6
Bremner, R.7
Park, D.S.8
Leone, G.9
Slack, R.S.10
-
152
-
-
37549016756
-
Specific in vivo roles for E2Fs in differentiation and development
-
McClellan K.A., Slack R.S., McClellan K.A., Slack R.S. Specific in vivo roles for E2Fs in differentiation and development. Cell Cycle 2007, 6:2917-2927.
-
(2007)
Cell Cycle
, vol.6
, pp. 2917-2927
-
-
McClellan, K.A.1
Slack, R.S.2
McClellan, K.A.3
Slack, R.S.4
-
153
-
-
0033578386
-
A mechanism for Rb/p130-mediated transcription repression involving recruitment of the CtBP corepressor
-
Meloni A.R., Smith E.J., Nevins J.R. A mechanism for Rb/p130-mediated transcription repression involving recruitment of the CtBP corepressor. Proc. Natl. Acad. Sci. USA 1999, 96:9574-9579.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 9574-9579
-
-
Meloni, A.R.1
Smith, E.J.2
Nevins, J.R.3
-
154
-
-
0141523025
-
Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model
-
Meuwissen R., Linn S.C., Linnoila R.I., Zevenhoven J., Mooi W.J., Berns A. Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model. Cancer Cell 2003, 4:181-189.
-
(2003)
Cancer Cell
, vol.4
, pp. 181-189
-
-
Meuwissen, R.1
Linn, S.C.2
Linnoila, R.I.3
Zevenhoven, J.4
Mooi, W.J.5
Berns, A.6
-
155
-
-
27644476029
-
Retinoblastoma protein acts as Pax 8 transcriptional coactivator
-
Miccadei S., Provenzano C., Mojzisek M., Giorgio Natali P., Civitareale D. Retinoblastoma protein acts as Pax 8 transcriptional coactivator. Oncogene 2005, 24:6993-7001.
-
(2005)
Oncogene
, vol.24
, pp. 6993-7001
-
-
Miccadei, S.1
Provenzano, C.2
Mojzisek, M.3
Giorgio Natali, P.4
Civitareale, D.5
-
156
-
-
0034458872
-
Cells degrade a novel inhibitor of differentiation with E1A-like properties upon exiting the cell cycle
-
Miyake S., Sellers W.R., Safran M., Li X., Zhao W., Grossman S.R., Gan J., DeCaprio J.A., Adams P.D., Kaelin W.G. Cells degrade a novel inhibitor of differentiation with E1A-like properties upon exiting the cell cycle. Mol. Cell. Biol. 2000, 20:8889-8902.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 8889-8902
-
-
Miyake, S.1
Sellers, W.R.2
Safran, M.3
Li, X.4
Zhao, W.5
Grossman, S.R.6
Gan, J.7
DeCaprio, J.A.8
Adams, P.D.9
Kaelin, W.G.10
-
157
-
-
61349117970
-
Genetics and epigenetics: Stability and plasticity during cellular differentiation
-
Mohn F., Schubeler D. Genetics and epigenetics: Stability and plasticity during cellular differentiation. Trends Genet. 2009, 25:129-136.
-
(2009)
Trends Genet.
, vol.25
, pp. 129-136
-
-
Mohn, F.1
Schubeler, D.2
-
158
-
-
77953158267
-
Progenitor stem cell marker expression by pulmonary carcinomas
-
Moreira A.L., Gonen M., Rekhtman N., Downey R.J. Progenitor stem cell marker expression by pulmonary carcinomas. Mod. Pathol. 2010, 23:889-895.
-
(2010)
Mod. Pathol.
, vol.23
, pp. 889-895
-
-
Moreira, A.L.1
Gonen, M.2
Rekhtman, N.3
Downey, R.J.4
-
160
-
-
75149172476
-
Cell cycle arrest by transforming growth factor beta1 near G1/S is mediated by acute abrogation of prereplication complex activation involving an Rb-MCM interaction
-
Mukherjee P., Winter S.L., Alexandrow M.G., Mukherjee P., Winter S.L., Alexandrow M.G. Cell cycle arrest by transforming growth factor beta1 near G1/S is mediated by acute abrogation of prereplication complex activation involving an Rb-MCM interaction. Mol. Cell. Biol. 2010, 30:845-856.
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 845-856
-
-
Mukherjee, P.1
Winter, S.L.2
Alexandrow, M.G.3
Mukherjee, P.4
Winter, S.L.5
Alexandrow, M.G.6
-
161
-
-
35548932872
-
A global double-fluorescent Cre reporter mouse
-
Muzumdar M.D., Tasic B., Miyamichi K., Li L., Luo L. A global double-fluorescent Cre reporter mouse. Genesis 2007, 45:593-605.
-
(2007)
Genesis
, vol.45
, pp. 593-605
-
-
Muzumdar, M.D.1
Tasic, B.2
Miyamichi, K.3
Li, L.4
Luo, L.5
-
162
-
-
65249093721
-
Aurora B kinase regulates the postmitotic endoreduplication checkpoint via phosphorylation of the retinoblastoma protein at serine 780
-
Nair J.S., Ho A.L., Tse A.N., Coward J., Cheema H., Ambrosini G., Keen N., Schwartz G.K., Nair J.S., Ho A.L., Tse A.N., Coward J., et al. Aurora B kinase regulates the postmitotic endoreduplication checkpoint via phosphorylation of the retinoblastoma protein at serine 780. Mol. Biol. Cell 2009, 20:2218-2228.
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 2218-2228
-
-
Nair, J.S.1
Ho, A.L.2
Tse, A.N.3
Coward, J.4
Cheema, H.5
Ambrosini, G.6
Keen, N.7
Schwartz, G.K.8
Nair, J.S.9
Ho, A.L.10
Tse, A.N.11
Coward, J.12
-
163
-
-
0037667702
-
Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence
-
Narita M., Nunez S., Heard E., Narita M., Lin A.W., Hearn S.A., Spector D.L., Hannon G.J., Lowe S.W. Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. Cell 2003, 113:703-716.
-
(2003)
Cell
, vol.113
, pp. 703-716
-
-
Narita, M.1
Nunez, S.2
Heard, E.3
Narita, M.4
Lin, A.W.5
Hearn, S.A.6
Spector, D.L.7
Hannon, G.J.8
Lowe, S.W.9
-
164
-
-
33746752125
-
A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation
-
Narita M., Narita M., Krizhanovsky V., Nunez S., Chicas A., Hearn S.A., Myers M.P., Lowe S.W. A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation. Cell 2006, 126:503-514.
-
(2006)
Cell
, vol.126
, pp. 503-514
-
-
Narita, M.1
Narita, M.2
Krizhanovsky, V.3
Nunez, S.4
Chicas, A.5
Hearn, S.A.6
Myers, M.P.7
Lowe, S.W.8
-
165
-
-
0141841682
-
Apoptotic and mitogenic stimuli inactivate Rb by differential utilization of p38 and cyclin-dependent kinases
-
Nath N., Wang S., Betts V., Knudsen E., Chellappan S. Apoptotic and mitogenic stimuli inactivate Rb by differential utilization of p38 and cyclin-dependent kinases. Oncogene 2003, 22:5986-5994.
-
(2003)
Oncogene
, vol.22
, pp. 5986-5994
-
-
Nath, N.1
Wang, S.2
Betts, V.3
Knudsen, E.4
Chellappan, S.5
-
166
-
-
24344507918
-
Role of the retinoblastoma tumor suppressor protein in cellular differentiation
-
Nguyen D.X., McCance D.J. Role of the retinoblastoma tumor suppressor protein in cellular differentiation. J. Cell. Biochem. 2005, 94:870-879.
-
(2005)
J. Cell. Biochem.
, vol.94
, pp. 870-879
-
-
Nguyen, D.X.1
McCance, D.J.2
-
167
-
-
0035797384
-
Rb targets histone H3 methylation and HP1 to promoters
-
Nielsen S.J., Schneider R., Bauer U.M., Bannister A.J., Morrison A., O'Carroll D., Firestein R., Cleary M., Jenuwein T., Herrera R.E., Kouzarides T. Rb targets histone H3 methylation and HP1 to promoters. Nature 2001, 412:561-565.
-
(2001)
Nature
, vol.412
, pp. 561-565
-
-
Nielsen, S.J.1
Schneider, R.2
Bauer, U.M.3
Bannister, A.J.4
Morrison, A.5
O'Carroll, D.6
Firestein, R.7
Cleary, M.8
Jenuwein, T.9
Herrera, R.E.10
Kouzarides, T.11
-
168
-
-
0029960519
-
Skeletal muscle cells lacking the retinoblastoma protein display defects in muscle gene expression and accumulate in S and G2 phases of the cell cycle
-
Novitch B.G., Mulligan G.J., Jacks T., Lassar A.B. Skeletal muscle cells lacking the retinoblastoma protein display defects in muscle gene expression and accumulate in S and G2 phases of the cell cycle. J. Cell Biol. 1996, 135:441-456.
-
(1996)
J. Cell Biol.
, vol.135
, pp. 441-456
-
-
Novitch, B.G.1
Mulligan, G.J.2
Jacks, T.3
Lassar, A.B.4
-
169
-
-
0033529030
-
PRb is required for MEF2-dependent gene expression as well as cell-cycle arrest during skeletal muscle differentiation
-
Novitch B.G., Spicer D.B., Kim P.S., Cheung W.L., Lassar A.B. pRb is required for MEF2-dependent gene expression as well as cell-cycle arrest during skeletal muscle differentiation. Curr. Biol. 1999, 9:449-459.
-
(1999)
Curr. Biol.
, vol.9
, pp. 449-459
-
-
Novitch, B.G.1
Spicer, D.B.2
Kim, P.S.3
Cheung, W.L.4
Lassar, A.B.5
-
170
-
-
34249290037
-
The lin-35/Rb and RNAi pathways cooperate to regulate a key cell cycle transition in C. elegans
-
Ouellet J., Roy R. The lin-35/Rb and RNAi pathways cooperate to regulate a key cell cycle transition in C. elegans. BMC Dev. Biol. 2007, 7:38.
-
(2007)
BMC Dev. Biol.
, vol.7
, pp. 38
-
-
Ouellet, J.1
Roy, R.2
-
171
-
-
0035265832
-
The C. elegans E2F- and DP-related proteins are required for embryonic asymmetry and negatively regulate Ras/MAPK signaling
-
Page B.D., Guedes S., Waring D., Priess J.R. The C. elegans E2F- and DP-related proteins are required for embryonic asymmetry and negatively regulate Ras/MAPK signaling. Mol. Cell 2001, 7:451-460.
-
(2001)
Mol. Cell
, vol.7
, pp. 451-460
-
-
Page, B.D.1
Guedes, S.2
Waring, D.3
Priess, J.R.4
-
172
-
-
18944364763
-
Interplay between the retinoblastoma protein and LEK1 specifies stem cells toward the cardiac lineage
-
Papadimou E., Menard C., Grey C., Puceat M. Interplay between the retinoblastoma protein and LEK1 specifies stem cells toward the cardiac lineage. EMBO J. 2005, 24:1750-1761.
-
(2005)
EMBO J.
, vol.24
, pp. 1750-1761
-
-
Papadimou, E.1
Menard, C.2
Grey, C.3
Puceat, M.4
-
173
-
-
0032735881
-
Regulation of postembryonic G(1) cell cycle progression in Caenorhabditis elegans by a cyclin D/CDK-like complex
-
Park M., Krause M.W. Regulation of postembryonic G(1) cell cycle progression in Caenorhabditis elegans by a cyclin D/CDK-like complex. Development 1999, 126:4849-4860.
-
(1999)
Development
, vol.126
, pp. 4849-4860
-
-
Park, M.1
Krause, M.W.2
-
174
-
-
0030690423
-
Modular organization of the E2F1 activation domain and its interaction with general transcription factors TBP and TFIIH
-
Pearson A., Greenblatt J. Modular organization of the E2F1 activation domain and its interaction with general transcription factors TBP and TFIIH. Oncogene 1997, 15:2643-2658.
-
(1997)
Oncogene
, vol.15
, pp. 2643-2658
-
-
Pearson, A.1
Greenblatt, J.2
-
175
-
-
18244428402
-
The large subunit of replication factor C promotes cell survival after DNA damage in an LxCxE motif- and Rb-dependent manner
-
Pennaneach V., Salles-Passador I., Munshi A., Brickner H., Regazzoni K., Dick F., Dyson N., Chen T.T., Wang J.Y., Fotedar R., Fotedar A. The large subunit of replication factor C promotes cell survival after DNA damage in an LxCxE motif- and Rb-dependent manner. Mol. Cell 2001, 7:715-727.
-
(2001)
Mol. Cell
, vol.7
, pp. 715-727
-
-
Pennaneach, V.1
Salles-Passador, I.2
Munshi, A.3
Brickner, H.4
Regazzoni, K.5
Dick, F.6
Dyson, N.7
Chen, T.T.8
Wang, J.Y.9
Fotedar, R.10
Fotedar, A.11
-
176
-
-
49649121765
-
E2F1 regulates autophagy and the transcription of autophagy genes
-
Polager S., Ofir M., Ginsberg D. E2F1 regulates autophagy and the transcription of autophagy genes. Oncogene 2008, 27:4860-4864.
-
(2008)
Oncogene
, vol.27
, pp. 4860-4864
-
-
Polager, S.1
Ofir, M.2
Ginsberg, D.3
-
177
-
-
41549149451
-
Cellular senescence in vivo: A barrier to tumorigenesis
-
Prieur A., Peeper D.S. Cellular senescence in vivo: A barrier to tumorigenesis. Curr. Opin. Cell Biol. 2008, 20:150-155.
-
(2008)
Curr. Opin. Cell Biol.
, vol.20
, pp. 150-155
-
-
Prieur, A.1
Peeper, D.S.2
-
178
-
-
0028856782
-
Dual retinoblastoma-binding proteins with properties related to a negative regulator of Ras in yeast
-
Qian Y.W., Lee E.Y. Dual retinoblastoma-binding proteins with properties related to a negative regulator of Ras in yeast. J. Biol. Chem. 1995, 270:25507-25513.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 25507-25513
-
-
Qian, Y.W.1
Lee, E.Y.2
-
179
-
-
0027320814
-
A retinoblastoma-binding protein related to a negative regulator of Ras in yeast
-
Qian Y.W., Wang Y.C., Hollingsworth R.E., Jones D., Ling N., Lee E.Y. A retinoblastoma-binding protein related to a negative regulator of Ras in yeast. Nature 1993, 364:648-652.
-
(1993)
Nature
, vol.364
, pp. 648-652
-
-
Qian, Y.W.1
Wang, Y.C.2
Hollingsworth, R.E.3
Jones, D.4
Ling, N.5
Lee, E.Y.6
-
180
-
-
0037080483
-
E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints
-
Ren B., Cam H., Takahashi Y., Volkert T., Terragni J., Young R.A., Dynlacht B.D. E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints. Genes Dev. 2002, 16:245-256.
-
(2002)
Genes Dev.
, vol.16
, pp. 245-256
-
-
Ren, B.1
Cam, H.2
Takahashi, Y.3
Volkert, T.4
Terragni, J.5
Young, R.A.6
Dynlacht, B.D.7
-
181
-
-
0033919595
-
DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters
-
Robertson K.D., Ait-Si-Ali S., Yokochi T., Wade P.A., Jones P.L., Wolffe A.P. DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters. Nat. Genet. 2000, 25:338-342.
-
(2000)
Nat. Genet.
, vol.25
, pp. 338-342
-
-
Robertson, K.D.1
Ait-Si-Ali, S.2
Yokochi, T.3
Wade, P.A.4
Jones, P.L.5
Wolffe, A.P.6
-
182
-
-
0033118363
-
ORC localization in Drosophila follicle cells and the effects of mutations in dE2F and dDP
-
Royzman I., Austin R.J., Bosco G., Bell S.P., Orr-Weaver T.L. ORC localization in Drosophila follicle cells and the effects of mutations in dE2F and dDP. Genes Dev. 1999, 13:827-840.
-
(1999)
Genes Dev.
, vol.13
, pp. 827-840
-
-
Royzman, I.1
Austin, R.J.2
Bosco, G.3
Bell, S.P.4
Orr-Weaver, T.L.5
-
183
-
-
28944437358
-
Structure of the Rb C-terminal domain bound to E2F1-DP1: A mechanism for phosphorylation-induced E2F release
-
Rubin S.M., Gall A.-L., Zheng N., Pavletich N.P. Structure of the Rb C-terminal domain bound to E2F1-DP1: A mechanism for phosphorylation-induced E2F release. Cell 2005, 123:1093-1106.
-
(2005)
Cell
, vol.123
, pp. 1093-1106
-
-
Rubin, S.M.1
Gall, A.-L.2
Zheng, N.3
Pavletich, N.P.4
-
184
-
-
3042813439
-
Unique and overlapping functions of pRb and p107 in the control of proliferation and differentiation in epidermis
-
Ruiz S., Santos M., Segrelles C., Leis H., Jorcano J.L., Berns A., Paramio J.M., Vooijs M. Unique and overlapping functions of pRb and p107 in the control of proliferation and differentiation in epidermis. Development 2004, 131:2737-2748.
-
(2004)
Development
, vol.131
, pp. 2737-2748
-
-
Ruiz, S.1
Santos, M.2
Segrelles, C.3
Leis, H.4
Jorcano, J.L.5
Berns, A.6
Paramio, J.M.7
Vooijs, M.8
-
185
-
-
0033637086
-
Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization
-
Sage J., Mulligan G.J., Attardi L.D., Miller A., Chen S., Williams B., Theodorou E., Jacks T. Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization. Genes Dev. 2000, 14:3037-3050.
-
(2000)
Genes Dev.
, vol.14
, pp. 3037-3050
-
-
Sage, J.1
Mulligan, G.J.2
Attardi, L.D.3
Miller, A.4
Chen, S.5
Williams, B.6
Theodorou, E.7
Jacks, T.8
-
186
-
-
0038342441
-
Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry
-
Sage J., Miller A.L., Perez-Mancera P.A., Wysocki J.M., Jacks T. Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry. Nature 2003, 424:223-228.
-
(2003)
Nature
, vol.424
, pp. 223-228
-
-
Sage, J.1
Miller, A.L.2
Perez-Mancera, P.A.3
Wysocki, J.M.4
Jacks, T.5
-
187
-
-
13844309351
-
Proliferation of functional hair cells in vivo in the absence of the retinoblastoma protein
-
Sage C., Huang M., Karimi K., Gutierrez G., Vollrath M.A., Zhang D.S., Garcia-Anoveros J., Hinds P.W., Corwin J.T., Corey D.P., Chen Z.Y. Proliferation of functional hair cells in vivo in the absence of the retinoblastoma protein. Science 2005, 307:1114-1118.
-
(2005)
Science
, vol.307
, pp. 1114-1118
-
-
Sage, C.1
Huang, M.2
Karimi, K.3
Gutierrez, G.4
Vollrath, M.A.5
Zhang, D.S.6
Garcia-Anoveros, J.7
Hinds, P.W.8
Corwin, J.T.9
Corey, D.P.10
Chen, Z.Y.11
-
188
-
-
0029064774
-
Molecular cloning of a human protein that binds to the retinoblastoma protein and chromosomal mapping
-
Saijo M., Sakai Y., Kishino T., Niikawa N., Matsuura Y., Morino K., Tamai K., Taya Y. Molecular cloning of a human protein that binds to the retinoblastoma protein and chromosomal mapping. Genomics 1995, 27:511-519.
-
(1995)
Genomics
, vol.27
, pp. 511-519
-
-
Saijo, M.1
Sakai, Y.2
Kishino, T.3
Niikawa, N.4
Matsuura, Y.5
Morino, K.6
Tamai, K.7
Taya, Y.8
-
189
-
-
54549104349
-
Chromatin dynamics during the plant cell cycle
-
Sanchez Mde L., Caro E., Desvoyes B., Ramirez-Parra E., Gutierrez C. Chromatin dynamics during the plant cell cycle. Semin. Cell Dev. Biol. 2008, 19:537-546.
-
(2008)
Semin. Cell Dev. Biol.
, vol.19
, pp. 537-546
-
-
Sanchez Mde, L.1
Caro, E.2
Desvoyes, B.3
Ramirez-Parra, E.4
Gutierrez, C.5
-
191
-
-
0028339957
-
Reversal of terminal differentiation mediated by p107 in Rb-/- muscle cells
-
Schneider J.W., Gu W., Zhu L., Mahdavi V., Nadal-Ginard B. Reversal of terminal differentiation mediated by p107 in Rb-/- muscle cells. Science 1994, 264:1467-1471.
-
(1994)
Science
, vol.264
, pp. 1467-1471
-
-
Schneider, J.W.1
Gu, W.2
Zhu, L.3
Mahdavi, V.4
Nadal-Ginard, B.5
-
192
-
-
0026484975
-
Molecular cloning of cellular genes encoding retinoblastoma- associated proteins: Identification of a gene with properties of the transcription factor E2F
-
Shan B., Zhu X., Chen P.L., Durfee T., Yang Y., Sharp D., Lee W.H. Molecular cloning of cellular genes encoding retinoblastoma- associated proteins: Identification of a gene with properties of the transcription factor E2F. Mol. Cell. Biol. 1992, 12:5620-5631.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 5620-5631
-
-
Shan, B.1
Zhu, X.2
Chen, P.L.3
Durfee, T.4
Yang, Y.5
Sharp, D.6
Lee, W.H.7
-
194
-
-
0036835483
-
The plant E2F-Rb pathway and epigenetic control
-
Shen W.H. The plant E2F-Rb pathway and epigenetic control. Trends Plant Sci. 2002, 7:505-511.
-
(2002)
Trends Plant Sci.
, vol.7
, pp. 505-511
-
-
Shen, W.H.1
-
195
-
-
0001510491
-
The RB and p53 pathways in cancer
-
Sherr C.J., McCormick F. The RB and p53 pathways in cancer. Cancer Cell 2002, 2:103-112.
-
(2002)
Cancer Cell
, vol.2
, pp. 103-112
-
-
Sherr, C.J.1
McCormick, F.2
-
196
-
-
33847638915
-
Loss of RB compromises specific heterochromatin modifications and modulates HP1alpha dynamics
-
Siddiqui H., Fox S.R., Gunawardena R.W., Knudsen E.S. Loss of RB compromises specific heterochromatin modifications and modulates HP1alpha dynamics. J. Cell. Physiol. 2007, 211:131-137.
-
(2007)
J. Cell. Physiol.
, vol.211
, pp. 131-137
-
-
Siddiqui, H.1
Fox, S.R.2
Gunawardena, R.W.3
Knudsen, E.S.4
-
197
-
-
0345306117
-
Transposon silencing in the Caenorhabditis elegans germ line by natural RNAi
-
Sijen T., Plasterk R.H. Transposon silencing in the Caenorhabditis elegans germ line by natural RNAi. Nature 2003, 426:310-314.
-
(2003)
Nature
, vol.426
, pp. 310-314
-
-
Sijen, T.1
Plasterk, R.H.2
-
198
-
-
0028986413
-
A role for retinoblastoma protein in potentiating transcriptional activation by the glucocorticoid receptor
-
Singh P., Coe J., Hong W. A role for retinoblastoma protein in potentiating transcriptional activation by the glucocorticoid receptor. Nature 1995, 374:562-565.
-
(1995)
Nature
, vol.374
, pp. 562-565
-
-
Singh, P.1
Coe, J.2
Hong, W.3
-
199
-
-
33845986330
-
Mad2 overexpression promotes aneuploidy and tumorigenesis in mice
-
Sotillo R., Hernando E., Diaz-Rodriguez E., Teruya-Feldstein J., Cordon-Cardo C., Lowe S.W., Benezra R. Mad2 overexpression promotes aneuploidy and tumorigenesis in mice. Cancer Cell 2007, 11:9-23.
-
(2007)
Cancer Cell
, vol.11
, pp. 9-23
-
-
Sotillo, R.1
Hernando, E.2
Diaz-Rodriguez, E.3
Teruya-Feldstein, J.4
Cordon-Cardo, C.5
Lowe, S.W.6
Benezra, R.7
-
200
-
-
9144223727
-
The Rb tumor suppressor is required for stress erythropoiesis
-
Spike B.T., Dirlam A., Dibling B.C., Marvin J., Williams B.O., Jacks T., Macleod K.F. The Rb tumor suppressor is required for stress erythropoiesis. EMBO J. 2004, 23:4319-4329.
-
(2004)
EMBO J.
, vol.23
, pp. 4319-4329
-
-
Spike, B.T.1
Dirlam, A.2
Dibling, B.C.3
Marvin, J.4
Williams, B.O.5
Jacks, T.6
Macleod, K.F.7
-
201
-
-
0031945518
-
Negative regulation of DNA replication by the retinoblastoma protein is mediated by its association with MCM7
-
Sterner J.M., Dew-Knight S., Musahl C., Kornbluth S., Horowitz J.M. Negative regulation of DNA replication by the retinoblastoma protein is mediated by its association with MCM7. Mol. Cell. Biol. 1998, 18:2748-2757.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 2748-2757
-
-
Sterner, J.M.1
Dew-Knight, S.2
Musahl, C.3
Kornbluth, S.4
Horowitz, J.M.5
-
202
-
-
0029995309
-
Functional interactions between the hBRM/hBRG1 transcriptional activators and the pRB family of proteins
-
Strober B.E., Dunaief J.L., Guha, Goff S.P. Functional interactions between the hBRM/hBRG1 transcriptional activators and the pRB family of proteins. Mol. Cell. Biol. 1996, 16:1576-1583.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 1576-1583
-
-
Strober, B.E.1
Dunaief, J.L.2
Guha3
Goff, S.P.4
-
203
-
-
0037154156
-
Characterization of protein kinase C beta isoform's action on retinoblastoma protein phosphorylation, vascular endothelial growth factor-induced endothelial cell proliferation, and retinal neovascularization
-
Suzuma K., Takahara N., Suzuma I., Isshiki K., Ueki K., Leitges M., Aiello L.P., King G.L. Characterization of protein kinase C beta isoform's action on retinoblastoma protein phosphorylation, vascular endothelial growth factor-induced endothelial cell proliferation, and retinal neovascularization. Proc. Natl. Acad. Sci. USA 2002, 99(2):721-726.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, Issue.2
, pp. 721-726
-
-
Suzuma, K.1
Takahara, N.2
Suzuma, I.3
Isshiki, K.4
Ueki, K.5
Leitges, M.6
Aiello, L.P.7
King, G.L.8
-
204
-
-
18244402890
-
Preferences for phosphorylation sites in the retinoblastoma protein of D-type cyclin-dependent kinases, Cdk4 and Cdk6, in vitro
-
Takaki T., Fukasawa K., Suzuki-Takahashi I., Semba K., Kitagawa M., Taya Y., Hirai H. Preferences for phosphorylation sites in the retinoblastoma protein of D-type cyclin-dependent kinases, Cdk4 and Cdk6, in vitro. J. Biochem. 2005, 137:381-386.
-
(2005)
J. Biochem.
, vol.137
, pp. 381-386
-
-
Takaki, T.1
Fukasawa, K.2
Suzuki-Takahashi, I.3
Semba, K.4
Kitagawa, M.5
Taya, Y.6
Hirai, H.7
-
205
-
-
71449108833
-
The chromosomal association of condensin II is regulated by a noncatalytic function of PP2A
-
Takemoto A., Maeshima K., Ikehara T., Yamaguchi K., Murayama A., Imamura S., Imamoto N., Yokoyama S., Hirano T., Watanabe Y., Hanaoka F., Yanagisawa J., et al. The chromosomal association of condensin II is regulated by a noncatalytic function of PP2A. Nat. Struct. Mol. Biol. 2009, 16:1302-1308.
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 1302-1308
-
-
Takemoto, A.1
Maeshima, K.2
Ikehara, T.3
Yamaguchi, K.4
Murayama, A.5
Imamura, S.6
Imamoto, N.7
Yokoyama, S.8
Hirano, T.9
Watanabe, Y.10
Hanaoka, F.11
Yanagisawa, J.12
-
206
-
-
0026329868
-
Nonfunctional mutants of the retinoblastoma protein are characterized by defects in phosphorylation, viral oncoprotein association, and nuclear tethering
-
Templeton D.J., Park S.H., Lanier L., Weinberg R.A. Nonfunctional mutants of the retinoblastoma protein are characterized by defects in phosphorylation, viral oncoprotein association, and nuclear tethering. Proc. Natl. Acad. Sci. USA 1991, 88:3033-3037.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 3033-3037
-
-
Templeton, D.J.1
Park, S.H.2
Lanier, L.3
Weinberg, R.A.4
-
207
-
-
0034840594
-
The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation
-
Thomas D.M., Carty S.A., Piscopo D.M., Lee J.S., Wang W.F., Forrester W.C., Hinds P.W. The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation. Mol. Cell 2001, 8:303-316.
-
(2001)
Mol. Cell
, vol.8
, pp. 303-316
-
-
Thomas, D.M.1
Carty, S.A.2
Piscopo, D.M.3
Lee, J.S.4
Wang, W.F.5
Forrester, W.C.6
Hinds, P.W.7
-
208
-
-
34548235820
-
BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy
-
Tracy K., Dibling B.C., Spike B.T., Knabb J.R., Schumacker P., Macleod K.F. BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy. Mol. Cell. Biol. 2007, 27:6229-6242.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 6229-6242
-
-
Tracy, K.1
Dibling, B.C.2
Spike, B.T.3
Knabb, J.R.4
Schumacker, P.5
Macleod, K.F.6
-
209
-
-
34249048369
-
L3MBTL1, a histone-methylation-dependent chromatin lock
-
Trojer P., Li G., Sims R.J., Vaquero A., Kalakonda N., Boccuni P., Lee D., Erdjument-Bromage H., Tempst P., Nimer S.D., Wang Y.H., Reinberg D. L3MBTL1, a histone-methylation-dependent chromatin lock. Cell 2007, 129:915-928.
-
(2007)
Cell
, vol.129
, pp. 915-928
-
-
Trojer, P.1
Li, G.2
Sims, R.J.3
Vaquero, A.4
Kalakonda, N.5
Boccuni, P.6
Lee, D.7
Erdjument-Bromage, H.8
Tempst, P.9
Nimer, S.D.10
Wang, Y.H.11
Reinberg, D.12
-
210
-
-
0030867899
-
RB and hbrm cooperate to repress the activation functions of E2F1
-
Trouche D., Le Chalony C., Muchardt C., Yaniv M., Kouzarides T. RB and hbrm cooperate to repress the activation functions of E2F1. Proc. Natl. Acad. Sci. USA 1997, 94:11268-11273.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 11268-11273
-
-
Trouche, D.1
Le Chalony, C.2
Muchardt, C.3
Yaniv, M.4
Kouzarides, T.5
-
211
-
-
0032159103
-
Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos
-
Tsai K.Y., Hu Y., Macleod K.F., Crowley D., Yamasaki L., Jacks T. Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos. Mol. Cell 1998, 2:293-304.
-
(1998)
Mol. Cell
, vol.2
, pp. 293-304
-
-
Tsai, K.Y.1
Hu, Y.2
Macleod, K.F.3
Crowley, D.4
Yamasaki, L.5
Jacks, T.6
-
213
-
-
77954516489
-
Loss of Rb proteins causes genomic instability in the absence of mitogenic signaling
-
van Harn T., Foijer F., van Vugt M., Banerjee R., Yang F., Oostra A., Joenje H., te Riele H. Loss of Rb proteins causes genomic instability in the absence of mitogenic signaling. Genes Dev. 2010, 24:1377-1388.
-
(2010)
Genes Dev.
, vol.24
, pp. 1377-1388
-
-
van Harn, T.1
Foijer, F.2
van Vugt, M.3
Banerjee, R.4
Yang, F.5
Oostra, A.6
Joenje, H.7
te Riele, H.8
-
214
-
-
77955122134
-
The retinoblastoma protein modulates Tbx2 functional specificity
-
21, 2770-2779
-
Vance K.W., Shaw H.M., Rodriguez M., Ott S., Goding C.R. The retinoblastoma protein modulates Tbx2 functional specificity. Mol. Biol. Cell 2010, 21, 2770-2779.
-
(2010)
Mol. Biol. Cell
-
-
Vance, K.W.1
Shaw, H.M.2
Rodriguez, M.3
Ott, S.4
Goding, C.R.5
-
215
-
-
0034811677
-
Transcriptional repression by the retinoblastoma protein through the recruitment of a histone methyltransferase
-
Vandel L., Nicolas E., Vaute O., Ferreira R., Ait-Si-Ali S., Trouche D. Transcriptional repression by the retinoblastoma protein through the recruitment of a histone methyltransferase. Mol. Cell. Biol. 2001, 21:6484-6494.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 6484-6494
-
-
Vandel, L.1
Nicolas, E.2
Vaute, O.3
Ferreira, R.4
Ait-Si-Ali, S.5
Trouche, D.6
-
216
-
-
4544363898
-
P107 regulates neural precursor cells in the mammalian brain
-
Vanderluit J.L., Ferguson K.L., Nikoletopoulou V., Parker M., Ruzhynsky V., Alexson T., McNamara S.M., Park D.S., Rudnicki M., Slack R.S. p107 regulates neural precursor cells in the mammalian brain. J. Cell Biol. 2004, 166:853-863.
-
(2004)
J. Cell Biol.
, vol.166
, pp. 853-863
-
-
Vanderluit, J.L.1
Ferguson, K.L.2
Nikoletopoulou, V.3
Parker, M.4
Ruzhynsky, V.5
Alexson, T.6
McNamara, S.M.7
Park, D.S.8
Rudnicki, M.9
Slack, R.S.10
-
217
-
-
0037079677
-
Functional and physical interaction between the histone methyl transferase Suv39H1 and histone deacetylases
-
Vaute O., Nicolas E., Vandel L., Trouche D. Functional and physical interaction between the histone methyl transferase Suv39H1 and histone deacetylases. Nucleic Acids Res. 2002, 30:475-481.
-
(2002)
Nucleic Acids Res.
, vol.30
, pp. 475-481
-
-
Vaute, O.1
Nicolas, E.2
Vandel, L.3
Trouche, D.4
-
218
-
-
18944394968
-
In vivo HP1 targeting causes large-scale chromatin condensation and enhanced histone lysine methylation
-
Verschure P.J., van der Kraan I., de Leeuw W., van der Vlag J., Carpenter A.E., Belmont A.S., van Driel R. In vivo HP1 targeting causes large-scale chromatin condensation and enhanced histone lysine methylation. Mol. Cell. Biol. 2005, 25:4552-4564.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 4552-4564
-
-
Verschure, P.J.1
van der Kraan, I.2
de Leeuw, W.3
van der Vlag, J.4
Carpenter, A.E.5
Belmont, A.S.6
van Driel, R.7
-
219
-
-
0032500170
-
Flp-mediated tissue-specific inactivation of the retinoblastoma tumor suppressor gene in the mouse
-
Vooijs M., van d.V., te R.H., Berns A. Flp-mediated tissue-specific inactivation of the retinoblastoma tumor suppressor gene in the mouse. Oncogene 1998, 17:1-12.
-
(1998)
Oncogene
, vol.17
, pp. 1-12
-
-
Vooijs, M.1
van, D.2
te, R.H.3
Berns, A.4
-
220
-
-
23144462374
-
Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants
-
Wang D., Kennedy S., Conte D., Kim J.K., Gabel H.W., Kamath R.S., Mello C.C., Ruvkun G. Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants. Nature 2005, 436:593-597.
-
(2005)
Nature
, vol.436
, pp. 593-597
-
-
Wang, D.1
Kennedy, S.2
Conte, D.3
Kim, J.K.4
Gabel, H.W.5
Kamath, R.S.6
Mello, C.C.7
Ruvkun, G.8
-
221
-
-
73349139851
-
Skp2 is required for survival of aberrantly proliferating Rb1-deficient cells and for tumorigenesis in Rb1+/- mice
-
Wang H., Bauzon F., Ji P., Xu X., Sun D., Locker J., Sellers R.S., Nakayama K., Nakayama K.I., Cobrinik D., Zhu L. Skp2 is required for survival of aberrantly proliferating Rb1-deficient cells and for tumorigenesis in Rb1+/- mice. Nat. Genet. 2010, 42:83-88.
-
(2010)
Nat. Genet.
, vol.42
, pp. 83-88
-
-
Wang, H.1
Bauzon, F.2
Ji, P.3
Xu, X.4
Sun, D.5
Locker, J.6
Sellers, R.S.7
Nakayama, K.8
Nakayama, K.I.9
Cobrinik, D.10
Zhu, L.11
-
222
-
-
0029033861
-
The retinoblastoma protein and cell cycle control
-
Weinberg R.A. The retinoblastoma protein and cell cycle control. Cell 1995, 81:323-330.
-
(1995)
Cell
, vol.81
, pp. 323-330
-
-
Weinberg, R.A.1
-
223
-
-
0027429964
-
A c-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle
-
Welch P.J., Wang J.Y.J. A c-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle. Cell 1993, 75:779-790.
-
(1993)
Cell
, vol.75
, pp. 779-790
-
-
Welch, P.J.1
Wang, J.Y.J.2
-
224
-
-
33846181043
-
Rb is critical in a mammalian tissue stem cell population
-
Wenzel P.L., Wu L., de Bruin A., Chong J.L., Chen W.Y., Dureska G., Sites E., Pan T., Sharma A., Huang K., Ridgway R., Mosaliganti K., et al. Rb is critical in a mammalian tissue stem cell population. Genes Dev. 2007, 21:85-97.
-
(2007)
Genes Dev.
, vol.21
, pp. 85-97
-
-
Wenzel, P.L.1
Wu, L.2
de Bruin, A.3
Chong, J.L.4
Chen, W.Y.5
Dureska, G.6
Sites, E.7
Pan, T.8
Sharma, A.9
Huang, K.10
Ridgway, R.11
Mosaliganti, K.12
-
225
-
-
4644257541
-
Rb family proteins differentially regulate distinct cell lineages during epithelial development
-
Wikenheiser-Brokamp K.A. Rb family proteins differentially regulate distinct cell lineages during epithelial development. Development 2004, 131:4299-4310.
-
(2004)
Development
, vol.131
, pp. 4299-4310
-
-
Wikenheiser-Brokamp, K.A.1
-
226
-
-
29244464678
-
The retinoblastoma-related gene regulates stem cell maintenance in arabidopsis roots
-
Wildwater M., Campilho A., Perez-Perez J.M., Heidstra R., Blilou I., Korthout H., Chatterjee J., Mariconti L., Gruissem W., Scheres B. The retinoblastoma-related gene regulates stem cell maintenance in arabidopsis roots. Cell 2005, 123:1337-1349.
-
(2005)
Cell
, vol.123
, pp. 1337-1349
-
-
Wildwater, M.1
Campilho, A.2
Perez-Perez, J.M.3
Heidstra, R.4
Blilou, I.5
Korthout, H.6
Chatterjee, J.7
Mariconti, L.8
Gruissem, W.9
Scheres, B.10
-
227
-
-
32044443208
-
The retinoblastoma protein is required for Ras-induced oncogenic transformation
-
Williams J.P., Stewart T., Li B., Mulloy R., Dimova D., Classon M., Williams J.P., Stewart T., Li B., Mulloy R., Dimova D., Classon M. The retinoblastoma protein is required for Ras-induced oncogenic transformation. Mol. Cell. Biol. 2006, 26:1170-1182.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 1170-1182
-
-
Williams, J.P.1
Stewart, T.2
Li, B.3
Mulloy, R.4
Dimova, D.5
Classon, M.6
Williams, J.P.7
Stewart, T.8
Li, B.9
Mulloy, R.10
Dimova, D.11
Classon, M.12
-
230
-
-
35748949600
-
Deacetylation of the retinoblastoma tumour suppressor protein by SIRT1
-
Wong S., Weber J.D. Deacetylation of the retinoblastoma tumour suppressor protein by SIRT1. Biochem. J. 2007, 407:451-460.
-
(2007)
Biochem. J.
, vol.407
, pp. 451-460
-
-
Wong, S.1
Weber, J.D.2
-
231
-
-
0035936113
-
The E2F1-3 transcription factors are essential for cellular proliferation
-
Wu L., Timmers C., Maiti B., Saavedra H.I., Sang L., Chong G.T., Nuckolls F., Giangrande P., Wright F.A., Field S.J., Greenberg M.E., Orkin S., et al. The E2F1-3 transcription factors are essential for cellular proliferation. Nature 2001, 414:457-462.
-
(2001)
Nature
, vol.414
, pp. 457-462
-
-
Wu, L.1
Timmers, C.2
Maiti, B.3
Saavedra, H.I.4
Sang, L.5
Chong, G.T.6
Nuckolls, F.7
Giangrande, P.8
Wright, F.A.9
Field, S.J.10
Greenberg, M.E.11
Orkin, S.12
-
232
-
-
0037468222
-
Extra-embryonic function of Rb is essential for embryonic development and viability
-
Wu L., de Bruin A., Saavedra H.I., Starovic M., Trimboli A., Yang Y., Opavska J., Wilson P., Thompson J.C., Ostrowski M.C., Rosol T.J., Woollett L.A., et al. Extra-embryonic function of Rb is essential for embryonic development and viability. Nature 2003, 421:942-947.
-
(2003)
Nature
, vol.421
, pp. 942-947
-
-
Wu, L.1
de Bruin, A.2
Saavedra, H.I.3
Starovic, M.4
Trimboli, A.5
Yang, Y.6
Opavska, J.7
Wilson, P.8
Thompson, J.C.9
Ostrowski, M.C.10
Rosol, T.J.11
Woollett, L.A.12
-
233
-
-
0035059136
-
Ebp1, an ErbB-3 binding protein, interacts with Rb and affects Rb transcriptional regulation
-
Xia X., Cheng A., Lessor T., Zhang Y., Hamburger A.W. Ebp1, an ErbB-3 binding protein, interacts with Rb and affects Rb transcriptional regulation. J. Cell. Physiol. 2001, 187:209-217.
-
(2001)
J. Cell. Physiol.
, vol.187
, pp. 209-217
-
-
Xia, X.1
Cheng, A.2
Lessor, T.3
Zhang, Y.4
Hamburger, A.W.5
-
234
-
-
0037418175
-
Crystal structure of the retinoblastoma tumor suppressor protein bound to E2F and the molecular basis of its regulation
-
Xiao B., Spencer J., Clements A., Ali-Khan N., Mittnacht S., Broceno C., Burghammer M., Perrakis A., Marmorstein R., Gamblin S.J. Crystal structure of the retinoblastoma tumor suppressor protein bound to E2F and the molecular basis of its regulation. Proc. Natl. Acad. Sci. USA 2003, 100:2363-2368.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 2363-2368
-
-
Xiao, B.1
Spencer, J.2
Clements, A.3
Ali-Khan, N.4
Mittnacht, S.5
Broceno, C.6
Burghammer, M.7
Perrakis, A.8
Marmorstein, R.9
Gamblin, S.J.10
-
235
-
-
66449114034
-
Retinoblastoma has properties of a cone precursor tumor and depends upon cone-specific MDM2 signaling
-
Xu X.L., Fang Y., Lee T.C., Forrest D., Gregory-Evans C., Almeida D., Liu A., Jhanwar S.C., Abramson D.H., Cobrinik D. Retinoblastoma has properties of a cone precursor tumor and depends upon cone-specific MDM2 signaling. Cell 2009, 137:1018-1031.
-
(2009)
Cell
, vol.137
, pp. 1018-1031
-
-
Xu, X.L.1
Fang, Y.2
Lee, T.C.3
Forrest, D.4
Gregory-Evans, C.5
Almeida, D.6
Liu, A.7
Jhanwar, S.C.8
Abramson, D.H.9
Cobrinik, D.10
-
236
-
-
43149108161
-
A bistable Rb-E2F switch underlies the restriction point
-
Yao G., Lee T.J., Mori S., Nevins J.R., You L., Yao G., Lee T.J., Mori S., Nevins J.R., You L. A bistable Rb-E2F switch underlies the restriction point. Nat. Cell Biol. 2008, 10:476-482.
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 476-482
-
-
Yao, G.1
Lee, T.J.2
Mori, S.3
Nevins, J.R.4
You, L.5
Yao, G.6
Lee, T.J.7
Mori, S.8
Nevins, J.R.9
You, L.10
-
237
-
-
0345598896
-
Distinct and nonoverlapping roles for pRB and cyclin D: Cyclin-dependent kinases 4/6 activity in melanocyte survival
-
Yu B.D., Becker-Hapak M., Snyder E.L., Vooijs M., Denicourt C., Dowdy S.F. Distinct and nonoverlapping roles for pRB and cyclin D: Cyclin-dependent kinases 4/6 activity in melanocyte survival. Proc. Natl. Acad. Sci. USA 2003, 100:14881-14886.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 14881-14886
-
-
Yu, B.D.1
Becker-Hapak, M.2
Snyder, E.L.3
Vooijs, M.4
Denicourt, C.5
Dowdy, S.F.6
-
238
-
-
0029819994
-
PRb controls proliferation, differentiation, and death of skeletal muscle cells and other lineages during embryogenesis
-
Zacksenhaus E., Jiang Z., Chung D., Marth J.D., Phillips R.A., Gallie B.L. pRb controls proliferation, differentiation, and death of skeletal muscle cells and other lineages during embryogenesis. Genes Dev. 1996, 10:3051-3064.
-
(1996)
Genes Dev.
, vol.10
, pp. 3051-3064
-
-
Zacksenhaus, E.1
Jiang, Z.2
Chung, D.3
Marth, J.D.4
Phillips, R.A.5
Gallie, B.L.6
-
239
-
-
0030918714
-
Differential phosphorylation of the retinoblastoma protein by G1/S cyclin-dependent kinases
-
Zarkowska T., Mittnacht S. Differential phosphorylation of the retinoblastoma protein by G1/S cyclin-dependent kinases. J. Biol. Chem. 1997, 272:12738-12746.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 12738-12746
-
-
Zarkowska, T.1
Mittnacht, S.2
-
240
-
-
1842588322
-
Rb regulates proliferation and rod photoreceptor development in the mouse retina
-
Zhang J., Gray J., Wu L., Leone G., Rowan S., Cepko C.L., Zhu X., Craft C.M., Dyer M.A. Rb regulates proliferation and rod photoreceptor development in the mouse retina. Nat. Genet. 2004, 36:351-360.
-
(2004)
Nat. Genet.
, vol.36
, pp. 351-360
-
-
Zhang, J.1
Gray, J.2
Wu, L.3
Leone, G.4
Rowan, S.5
Cepko, C.L.6
Zhu, X.7
Craft, C.M.8
Dyer, M.A.9
-
241
-
-
19944427674
-
Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA
-
Zhang R., Poustovoitov M.V., Ye X., Santos H.A., Chen W., Daganzo S.M., Erzberger J.P., Serebriiskii I.G., Canutescu A.A., Dunbrack R.L., Pehrson J.R., Berger J.M., et al. Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA. Dev. Cell 2005, 8:19-30.
-
(2005)
Dev. Cell
, vol.8
, pp. 19-30
-
-
Zhang, R.1
Poustovoitov, M.V.2
Ye, X.3
Santos, H.A.4
Chen, W.5
Daganzo, S.M.6
Erzberger, J.P.7
Serebriiskii, I.G.8
Canutescu, A.A.9
Dunbrack, R.L.10
Pehrson, J.R.11
Berger, J.M.12
-
242
-
-
0036569924
-
Deficiency of Retinoblastoma gene in mouse embryonic stem cells leads to genetic instability
-
Zheng L., Flesken-Nikitin A., Chen P.L., Lee W.H. Deficiency of Retinoblastoma gene in mouse embryonic stem cells leads to genetic instability. Cancer Res. 2002, 62:2498-2502.
-
(2002)
Cancer Res.
, vol.62
, pp. 2498-2502
-
-
Zheng, L.1
Flesken-Nikitin, A.2
Chen, P.L.3
Lee, W.H.4
-
243
-
-
33748078111
-
Synergy of p53 and Rb deficiency in a conditional mouse model for metastatic prostate cancer
-
Zhou Z., Flesken-Nikitin A., Corney D.C., Wang W., Goodrich D.W., Roy-Burman P., Nikitin A.Y. Synergy of p53 and Rb deficiency in a conditional mouse model for metastatic prostate cancer. Cancer Res. 2006, 66:7889-7898.
-
(2006)
Cancer Res.
, vol.66
, pp. 7889-7898
-
-
Zhou, Z.1
Flesken-Nikitin, A.2
Corney, D.C.3
Wang, W.4
Goodrich, D.W.5
Roy-Burman, P.6
Nikitin, A.Y.7
-
244
-
-
34250822389
-
Prostate cancer associated with p53 and Rb deficiency arises from the stem/progenitor cell-enriched proximal region of prostatic ducts
-
Zhou Z., Flesken-Nikitin A., Nikitin A.Y. Prostate cancer associated with p53 and Rb deficiency arises from the stem/progenitor cell-enriched proximal region of prostatic ducts. Cancer Res. 2007, 67:5683-5690.
-
(2007)
Cancer Res.
, vol.67
, pp. 5683-5690
-
-
Zhou, Z.1
Flesken-Nikitin, A.2
Nikitin, A.Y.3
|