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Volumn 2, Issue 6, 2002, Pages 463-472

E2F4 loss suppresses tumorigenesis in Rb mutant mice

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P107; PROTEIN P130; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F4; CYCLIN E; DNA BINDING PROTEIN; NUCLEAR PROTEIN; PHOSPHOPROTEIN; PROTEIN; RBL1 PROTEIN, MOUSE; RBL2 PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

EID: 0001445037     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1535-6108(02)00207-6     Document Type: Article
Times cited : (110)

References (46)
  • 1
    • 0027434084 scopus 로고
    • Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F
    • Bandara, L.R., Buck, V.M., Zamanian, M., Johnston, L.H., and La Thangue, N.B. (1993). Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F. EMBO J. 12, 4317-4324.
    • (1993) EMBO J. , vol.12 , pp. 4317-4324
    • Bandara, L.R.1    Buck, V.M.2    Zamanian, M.3    Johnston, L.H.4    La Thangue, N.B.5
  • 2
    • 0030561571 scopus 로고    scopus 로고
    • The retinoblastoma protein pathway and the restriction point
    • Bartek, J., Bartkova, J., and Lukas, J. (1996). The retinoblastoma protein pathway and the restriction point. Curr. Opin. Cell Biol. 8, 805-814.
    • (1996) Curr. Opin. Cell Biol. , vol.8 , pp. 805-814
    • Bartek, J.1    Bartkova, J.2    Lukas, J.3
  • 3
    • 0027985749 scopus 로고
    • E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo
    • Beijersbergen, R.L., Kerkhoven, R.M., Zhu, L., Carlee, L., Voorhoeve, P.M., and Bernards, R. (1994). E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo. Genes Dev. 8, 2680-2690.
    • (1994) Genes Dev. , vol.8 , pp. 2680-2690
    • Beijersbergen, R.L.1    Kerkhoven, R.M.2    Zhu, L.3    Carlee, L.4    Voorhoeve, P.M.5    Bernards, R.6
  • 5
    • 0034650850 scopus 로고    scopus 로고
    • Mutations in the retinoblastoma-related gene RB2/p130 in lung tumors and suppression of tumor growth in vivo by retrovirus-mediated gene transfer
    • Claudio, P.P., Howard, C.M., Pacilio, C., Cinti, C., Romano, G., Minimo, C., Maraldi, N.M., Minna, J.D., Gelbert, L., Leoncini, L., et al. (2000b). Mutations in the retinoblastoma-related gene RB2/p130 in lung tumors and suppression of tumor growth in vivo by retrovirus-mediated gene transfer. Cancer Res. 60, 372-382.
    • (2000) Cancer Res. , vol.60 , pp. 372-382
    • Claudio, P.P.1    Howard, C.M.2    Pacilio, C.3    Cinti, C.4    Romano, G.5    Minimo, C.6    Maraldi, N.M.7    Minna, J.D.8    Gelbert, L.9    Leoncini, L.10
  • 8
    • 0033635597 scopus 로고    scopus 로고
    • Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions
    • Dannenberg, J.H., van Rossum, A., Schuijff, L., and te Riele, H. (2000). Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions. Genes Dev. 14, 3051-3064.
    • (2000) Genes Dev. , vol.14 , pp. 3051-3064
    • Dannenberg, J.H.1    Van Rossum, A.2    Schuijff, L.3    Te Riele, H.4
  • 10
    • 0032146274 scopus 로고    scopus 로고
    • The regulation of E2F by pRB-family proteins
    • Dyson, N. (1998). The regulation of E2F by pRB-family proteins. Genes Dev. 12, 2245-2262.
    • (1998) Genes Dev. , vol.12 , pp. 2245-2262
    • Dyson, N.1
  • 12
    • 0035146678 scopus 로고    scopus 로고
    • E2F4 is exported from the nucleus in a CRM1-dependent manner
    • Gaubatz, S., Lees, J.A., Lindeman, G.J., and Livingston, D.M. (2001). E2F4 is exported from the nucleus in a CRM1-dependent manner. Mol. Cell. Biol. 21, 1384-1392.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 1384-1392
    • Gaubatz, S.1    Lees, J.A.2    Lindeman, G.J.3    Livingston, D.M.4
  • 14
    • 0031886093 scopus 로고    scopus 로고
    • Regulation of cell proliferation by the E2F transcription factors
    • Helin, K. (1998). Regulation of cell proliferation by the E2F transcription factors. Curr. Opin. Genet. Dev. 8, 28-35.
    • (1998) Curr. Opin. Genet. Dev. , vol.8 , pp. 28-35
    • Helin, K.1
  • 15
    • 0027426917 scopus 로고
    • Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation
    • Helin, K., Wu, C.L., Fattaey, A.R., Lees, J.A., Dynlacht, B.D., Ngwu, C., and Harlow, E. (1993). Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation. Genes Dev. 7, 1850-1861.
    • (1993) Genes Dev. , vol.7 , pp. 1850-1861
    • Helin, K.1    Wu, C.L.2    Fattaey, A.R.3    Lees, J.A.4    Dynlacht, B.D.5    Ngwu, C.6    Harlow, E.7
  • 17
    • 0029863840 scopus 로고    scopus 로고
    • Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts
    • Herrera, R.E., Sah, V.P., Williams, B.O., Makela, T.P., Weinberg, R.A., and Jacks, T. (1996). Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts. Mol. Cell. Biol. 16, 2402-2407.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2402-2407
    • Herrera, R.E.1    Sah, V.P.2    Williams, B.O.3    Makela, T.P.4    Weinberg, R.A.5    Jacks, T.6
  • 21
    • 15444353328 scopus 로고    scopus 로고
    • pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes
    • Hurford, R.K., Jr., Cobrinik, D., Lee, M.-H., and Dyson, N. (1997). pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes. Genes Dev. 11, 1447-1463.
    • (1997) Genes Dev. , vol.11 , pp. 1447-1463
    • Hurford Jr., R.K.1    Cobrinik, D.2    Lee, M.-H.3    Dyson, N.4
  • 23
    • 0027769885 scopus 로고
    • Binding to DNA and the retinoblastoma gene product promoted by complex formation of different E2F family members
    • Krek, W., Livingston, D.M., and Shirodkar, S. (1993). Binding to DNA and the retinoblastoma gene product promoted by complex formation of different E2F family members. Science 262, 1557-1560.
    • (1993) Science , vol.262 , pp. 1557-1560
    • Krek, W.1    Livingston, D.M.2    Shirodkar, S.3
  • 25
    • 0030053130 scopus 로고    scopus 로고
    • Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4A-mediated growth suppression
    • Lukas, J., Petersen, B.O., Holm, K., Bartek, J., and Helin, K. (1996). Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4A-mediated growth suppression. Mol. Cell. Biol. 16, 1047-1057.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1047-1057
    • Lukas, J.1    Petersen, B.O.2    Holm, K.3    Bartek, J.4    Helin, K.5
  • 26
    • 0029991715 scopus 로고    scopus 로고
    • Nuclear localization of DP and E2F transcription factors by heterodimeric partners and retinoblastoma protein family members
    • Magae, J., Wu, C.L., Illenye, S., Harlow, E., and Heintz, N.H. (1996). Nuclear localization of DP and E2F transcription factors by heterodimeric partners and retinoblastoma protein family members. J. Cell Sci. 109, 1717-1726.
    • (1996) J. Cell Sci. , vol.109 , pp. 1717-1726
    • Magae, J.1    Wu, C.L.2    Illenye, S.3    Harlow, E.4    Heintz, N.H.5
  • 27
    • 0029978325 scopus 로고    scopus 로고
    • E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentry
    • Moberg, K., Starz, M.A., and Lees, J.A. (1996). E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentry. Mol. Cell. Biol. 16, 1436-1449.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1436-1449
    • Moberg, K.1    Starz, M.A.2    Lees, J.A.3
  • 28
    • 0039227088 scopus 로고    scopus 로고
    • Induction of S-phase entry by E2F transcription factors depends on their nuclear localization
    • Muller, H., Moroni, M.C., Vigo, E., Petersen, B.O., Bartek, J., and Helin, K. (1997). Induction of S-phase entry by E2F transcription factors depends on their nuclear localization. Mol. Cell. Biol. 17, 5508-5520.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 5508-5520
    • Muller, H.1    Moroni, M.C.2    Vigo, E.3    Petersen, B.O.4    Bartek, J.5    Helin, K.6
  • 29
    • 0031831681 scopus 로고    scopus 로고
    • The retinoblastoma gene family: Cousins with overlapping interests
    • Mulligan, G., and Jacks, T. (1998). The retinoblastoma gene family: cousins with overlapping interests. Trends Genet. 14, 223-229.
    • (1998) Trends Genet. , vol.14 , pp. 223-229
    • Mulligan, G.1    Jacks, T.2
  • 32
    • 0037080483 scopus 로고    scopus 로고
    • E2F integrates cell cycle progression with DNA repair, replication, and G2/M checkpoints
    • Ren, B., Cam, H., Takahashi, Y., Volkert, T., Terragni, J., Young, R.A., and Dynlacht, B.D. (2002). E2F integrates cell cycle progression with DNA repair, replication, and G2/M checkpoints. Genes Dev. 16, 245-256.
    • (2002) Genes Dev. , vol.16 , pp. 245-256
    • Ren, B.1    Cam, H.2    Takahashi, Y.3    Volkert, T.4    Terragni, J.5    Young, R.A.6    Dynlacht, B.D.7
  • 34
    • 0033637086 scopus 로고    scopus 로고
    • Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization
    • Sage, J., Mulligan, G.J., Attardi, L.D., Miller, A., Chen, S., Williams, B., Theodorou, E., and Jacks, T. (2000). Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization. Genes Dev. 14, 3037-3050.
    • (2000) Genes Dev. , vol.14 , pp. 3037-3050
    • Sage, J.1    Mulligan, G.J.2    Attardi, L.D.3    Miller, A.4    Chen, S.5    Williams, B.6    Theodorou, E.7    Jacks, T.8
  • 35
  • 36
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr, C.J. (1996). Cancer cell cycles. Science 274, 1672-1677.
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 37
    • 0034175616 scopus 로고    scopus 로고
    • Analysis of promoter binding by the E2F and pRB families in vivo: Distinct E2F proteins mediate activation and repression
    • Takahashi, Y., Rayman, J.B., and Dynlacht, B.D. (2000). Analysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repression. Genes Dev. 14, 804-816.
    • (2000) Genes Dev. , vol.14 , pp. 804-816
    • Takahashi, Y.1    Rayman, J.B.2    Dynlacht, B.D.3
  • 39
    • 0032159103 scopus 로고    scopus 로고
    • Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos
    • Tsai, K.Y., Hu, Y., Macleod, K.F., Crowley, D., Yamasaki, L., and Jacks, T. (1998). Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos. Mol. Cell 2, 293-304.
    • (1998) Mol. Cell , vol.2 , pp. 293-304
    • Tsai, K.Y.1    Hu, Y.2    Macleod, K.F.3    Crowley, D.4    Yamasaki, L.5    Jacks, T.6
  • 40
    • 0030667320 scopus 로고    scopus 로고
    • E2F activity is regulated by cell cycle-dependent changes in subcellular localization
    • Verona, R., Moberg, K., Estes, S., Starz, M., Vernon, J.P., and Lees, J.A. (1997). E2F activity is regulated by cell cycle-dependent changes in subcellular localization. Mol. Cell. Biol. 17, 7268-7282.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 7268-7282
    • Verona, R.1    Moberg, K.2    Estes, S.3    Starz, M.4    Vernon, J.P.5    Lees, J.A.6
  • 41
    • 1842413645 scopus 로고    scopus 로고
    • p130 and p107 use a conserved domain to inhibit cellular cyclin-dependent kinase activity
    • Woo, M.S., Sanchez, I., and Dynlacht, B.D. (1997). p130 and p107 use a conserved domain to inhibit cellular cyclin-dependent kinase activity. Mol. Cell. Biol. 17, 3566-3579.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 3566-3579
    • Woo, M.S.1    Sanchez, I.2    Dynlacht, B.D.3
  • 43
    • 0031897273 scopus 로고    scopus 로고
    • Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-)mice
    • Yamasaki, L., Bronson, R., Williams, B.O., Dyson, N.J., Harlow, E., and Jacks, T. (1998). Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-)mice. Nat. Genet. 18, 360-364.
    • (1998) Nat. Genet. , vol.18 , pp. 360-364
    • Yamasaki, L.1    Bronson, R.2    Williams, B.O.3    Dyson, N.J.4    Harlow, E.5    Jacks, T.6
  • 44
    • 0033515424 scopus 로고    scopus 로고
    • Active transcriptional repression by the Rb-E2F complex mediates G1 arrest triggered by p16INK4a, TGFbeta, and contact inhibition
    • Zhang, H.S., Postigo, A.A., and Dean, D.C. (1999). Active transcriptional repression by the Rb-E2F complex mediates G1 arrest triggered by p16INK4a, TGFbeta, and contact inhibition. Cell 97, 53-61.
    • (1999) Cell , vol.97 , pp. 53-61
    • Zhang, H.S.1    Postigo, A.A.2    Dean, D.C.3
  • 45
    • 0034737290 scopus 로고    scopus 로고
    • Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF
    • Zhang, H.S., Gavin, M., Dahiya, A., Postigo, A.A., Ma, D., Luo, R.X., Harbour, J.W., and Dean, D.C. (2000). Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF. Cell 101, 79-89.
    • (2000) Cell , vol.101 , pp. 79-89
    • Zhang, H.S.1    Gavin, M.2    Dahiya, A.3    Postigo, A.A.4    Ma, D.5    Luo, R.X.6    Harbour, J.W.7    Dean, D.C.8
  • 46
    • 0035118893 scopus 로고    scopus 로고
    • E2F3 contributes both to the inappropriate proliferation and to the apoptosis arising in Rb mutant embryos
    • Ziebold, U., Reza, T., Caron, A., and Lees, J.A. (2001). E2F3 contributes both to the inappropriate proliferation and to the apoptosis arising in Rb mutant embryos. Genes Dev. 15, 386-391.
    • (2001) Genes Dev. , vol.15 , pp. 386-391
    • Ziebold, U.1    Reza, T.2    Caron, A.3    Lees, J.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.