The role of RBF in the introduction of G1 regulation during Drosophila embryogenesis

EMBO Journal

Volumn 18, Issue 4, 1999, Pages 916-925

  Du, Wei ^a,b   Dyson, Nicholas ^a  

^a MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

Cell cycle; Drosophila; Embryogenesis; RBF; Transcription factor E2F

Indexed keywords

CELL PROTEIN; CYCLINE; TRANSCRIPTION FACTOR E2F;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CONTROLLED STUDY; DROSOPHILA; EMBRYO; FEMALE; GENE EXPRESSION; GENE MUTATION; MALE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; TRANSCRIPTION REGULATION;

ANIMALS; CARRIER PROTEINS; CELL CYCLE; CELL CYCLE PROTEINS; CYCLIN-DEPENDENT KINASES; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; E2F TRANSCRIPTION FACTORS; EMBRYONIC DEVELOPMENT; EYE; G1 PHASE; GENE DELETION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IN SITU HYBRIDIZATION; MICROSCOPY, ELECTRON, SCANNING; MUTATION; PHENOTYPE; REPRESSOR PROTEINS; RETINOBLASTOMA PROTEIN; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

ANIMALIA; ARACHNIDA; HEXAPODA;

EID: 0033558346     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/18.4.916     Document Type: Article

References (49)

1. Asano, M., Nevins, J.R. and Wharton, R.P. (1996) Ectopic E2F expression induces S phase and apoptosis in Drosophila imaginal discs. Genes Dev., 10, 1422-1432.
2. Brodsky, V.Y. and Uryvaeva, I.V. (1984) Genome Multiplication in Growth and Development: Biology of Polyploid and Polytene Cells. Cambridge University Press, New York, NY.
3. Clarke, A., Maandag, E., van Roon, M., van der Lugt, N., van der Valk, M., Hooper, M., Berns, A. and te Riele, H. (1992) Requirement for a functional Rb-1 gene in murine development. Nature, 359, 328-330.
4. Cobrinik, D. et al. (1996) Shared role of the pRB-related p130 and p107 proteins in limb development. Genes Dev. 10, 1633-1644.
5. Dalby, B., Pereira, A.J. and Goldstein, L.S. (1995) An inverse PCR screen for the detection of P element insertions in cloned genomic intervals in Drosophila melanogaster. Genetics, 139, 757-766.
6. Dawson, I.A., Roth, S. and Artavanis-Tsakonas, S. (1995) The Drosophila cell cycle gene fizzy is required for normal degradation of cyclins A and B during mitosis and has homology to the CDC20 gene of Saccharomyces cerevisiae. J. Cell Biol., 129, 725-737.
7. de Nooij, J.C. and Hariharan, I.K. (1995) Uncoupling cell fate determination from patterned cell division in the Drosophila eye. Science, 270, 983-985.
8. de Nooij, J.C., Letendre, M.A. and Hariharan, I.K. (1996) A cyclin-dependent kinase inhibitor, dacapo, is necessary for timely exit from the cell cycle during Drosophila embryogenesis. Cell, 87, 1237-1247.
9. Du, W., Vidal, M., Xie, J.-E. and Dyson, N. (1996a) RBF, a novel RB-related gene that regulates E2F activity and interacts with cyclin E in Drosophila. Genes Dev., 10, 1206-1218.
10. Du, W., Xie, J.-E. and Dyson, N. (1996b) Ectopic expression of dE2F and dDP induces cell proliferation and death in the Drosophila eye. EMBO J., 15, 3684-3692.
11. 1-S transcriptional program in Drosophila. Development, 120, 1503-1515.
12. 1 to S transition in Drosophila: cyclin E is a limiting downstream target of E2F. Genes Dev., 9, 1456-1468.
13. Duronio, R.J., O'Farrell, P.H., Xie, J.-E., Brook, A. and Dyson, N. (1995) The transcription factor E2F is required for S phase during Drosophila embryogenesis. Genes Dev., 9, 1445-1455.
14. Duronio, R.J., Brook, A., Dyson, N. and O'Farrell, P.H. (1996) E2F-induced S phase requires cyclin E. Genes Dev., 10, 2505-2513.
15. Duronio, R.J., Bonnette, P.C. and O'Farrell, P.H. (1998) Mutations of the Drosophila dDP, dE2F, and cyclin E genes reveal distinct roles for the E2F-DP transcription factor and cyclin E during the S-phase transition. Mol. Cell. Biol., 18, 141-151.
16. Dyson, N. (1998) The regulation of E2F by pRB-family proteins. Genes Dev., 12, 2245-2262.
17. Edgar, B.A. and O'Farrell, P.H. (1989) Genetic control of cell division patterns in the Drosophila embryo. Cell, 57, 177-187.
18. 2 by string. Cell, 62, 469-480.
19. Edgar, B.A. and Datar, S.A. (1996) Zygotic degradation of two maternal Cdc25 mRNAs terminates Drosophila's early cell cycle program. Genes Dev., 10, 1966-1977.
20. Foe, V.E. (1989) Mitotic domains reveal early commitment of cells in Drosophila embryos. Development, 107, 1-22.
21. Foe, V.A. and Alberts, B.M. (1983) Studies of nuclear and cytoplasmic behavior during the five mitotic cycles that precede gastrulation in Drosophila embryogenesis. J. Cell Sci., 61, 31-70.
22. Foe, V.E., Odell, G.M. and Edgar, B.A. (1993) Mitosis and morphogenesis in the Drosophila embryo: point and counterpoint. In Bate, M. and Martinez-Arias, A. (eds). The Development of Drosophila melanogaster. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 149-300.
23. Follet, P.J., Duronio, R.J. and O'Farrell, P.H. (1998) Fluctuations in cyclin E levels are required for multiple rounds of endocyde S-phase in Drosophila. Curr. Biol., 8, 235-238.
24. Hao, X.F., Alphey, L., Bandara, L.R., Lam, E.W.-F., Glover, D. and La Thangue, N.B. (1995) Functional conservation of the cell cycle-regulating transcription factor DRTF1/E2F and its pathway of control in Drosophila melanogaster. J. Cell Sci., 108, 2945-2954.
25. Jacks, T., Fazeli, A., Schmitt, E., Bronson, R., Goodell, M. and Weinberg, R. (1992) Effects of an Rb mutation in the mouse. Nature, 359, 295-300.
26. Knoblich, J.A., Sauer, K., Jones, L., Richardson, H., Saint, R. and Lehner, C.F. (1994) Cyclin E controls S-phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation. Cell, 77, 107-120.
27. Kowalik, T.F., DeGregori, J., Schwarz, J.K. and Nevins, J.R. (1995) E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis. J. Virol., 69, 2491-2500.
28. Krek, W., Xu, G. and Livingston, D.M. (1995) Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint. Cell, 83, 1149-1158.
29. Lane, M.E., Sauer, K., Wallace, K., Jan, Y.N., Lehner, C.F. and Vaessin, H. (1996) Dacapo, a cyclin-dependent kinase inhibitor, stops cell proliferation during Drosophila development. Cell, 87, 1225-1235.
30. Lee, E.Y., Chang, C.Y., Hu, N., Wang, Y.C., Lai, C.C., Herrup, K., Lee, W.-H. and Bradley, A. (1992) Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis. Nature, 359, 288-294.
31. Lee, E.Y.-H.P., Hu, N., Yuan, S.-S.F., Cox, L.A., Bradley, A., Lee, W.-H. and Herrup, K. (1994) Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation. Genes Dev., 8, 2008-2021.
32. Lee, M.-H., Williams, B.O., Mulligan, G., Mukai, S., Bronson, R.T., Dyson, N., Harlow, E. and Jacks, T. (1996) Targeted disruption of p107: functional overlap between p107 and Rb. Genes Dev., 10, 1621-1632.
33. Lehner, C.F. and O'Farrell, P.H. (1989) Expression and function of Drosophila cyclin A during embryonic cell cycle progression. Cell, 56, 957-968.
34. Lehner, C.F. and O'Farrell, P.H. (1990) The roles of Drosophila cyclins A and B in mitotic control. Cell, 61, 535-547.
35. MacAuley, A., Cross, J.C. and Werb, Z. (1998) Reprogramming the cell cycle for endoreduplication in rodent trophoblast cells. Mol. Biol. Cell, 9, 795-807.
36. Mulligan, G. and Jacks, J. (1998) The retinoblastoma gene family: cousins with overlapping interests. Trends Genet., 14, 223-229.
37. Nagl, W. (1978) Endopolyploidy and Polyteny in Differentiation and Evolution: Towards an Understanding of Quantitative and Qualitative Variation of Nuclear DNA in Ontogeny and Phylogeny. North-Holland Publishing Co., New York, NY.
38. Qin, X.-Q., Livingston, D.M., Kaelin, W.G.J. and Adams, P. (1994) Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis. Proc. Natl Acad. Sci. USA, 91, 10918-10922.
39. 1-specific cyclin E homolog exhibits different modes of expression during embryogenesis. Development, 119, 673-690.
40. Richardson, H., O'Keefe, L.V., Marty, T. and Saint, R. (1995) Ectopic cyclin E expression induces premature entry into S-phase and disrupts pattern formation in the Drosophila eye imaginai disc. Development. 121, 3371-3379.
41. 1-S progression from an associated transcriptional program. Genes Dev., 11, 1999-2011.
42. Shan, B. and Lee, W.-H. (1994) Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis. Mol. Cell Biol., 14, 8166-8173.
43. Sigrist, S.J. and Lehner, C.F. (1997) Drosophila fizzy-related down regulates cyclins and is required for cell proliferation arrest and entry into endocycles. Cell. 90, 671-681.
44. Sigrist, S.J., Jacobs, H., Stratmann, R. and Lehner, C.F. (1995) Exit from mitosis is regulated by Drosophila fizzy and the sequential destruction of cyclins A, B and B3. EMBO J., 14, 4827-4838.
45. Smith, A.V. and Orr-Weaver, T.L. (1991) The regulation of the cell cycle during Drosophila embryogenesis: the transition to polyteny. Development, 112, 997-1008.
46. Soto, M.C. Chou, T. and Bender, W. (1995) Comparison of germline mosaics of genes in the polycomb group of Drosophila melanogaster. Genetics, 140, 231-243.
47. Spradling, A. and Orr-Weaver, T.L. (1987) Regulation of DNA replication during Drosophila development. Annu. Rev. Genet., 21, 373-403.
48. Weiss, A., Herzig, A., Jacobs, H. and Lehner, C.F. (1998) Continuous cyclin E expression inhibits progression through endoreduplication cycles in Drosophila. Curr. Biol., 8, 239-242.
49. Wu, X. and Levine, A.J. (1994) p53 and E2F-1 cooperate to mediate apoptosis. Proc. Natl Acad. Sci. USA. 91, 3602-3606.