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Volumn 25, Issue 3, 2009, Pages 129-136

Genetics and epigenetics: stability and plasticity during cellular differentiation

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE H3; LYSINE; POLYCOMB GROUP PROTEIN;

EID: 61349117970     PISSN: 01689525     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tig.2008.12.005     Document Type: Review
Times cited : (228)

References (87)
  • 1
    • 34249279527 scopus 로고    scopus 로고
    • Stability and flexibility of epigenetic gene regulation in mammalian development
    • Reik W. Stability and flexibility of epigenetic gene regulation in mammalian development. Nature 447 (2007) 425-432
    • (2007) Nature , vol.447 , pp. 425-432
    • Reik, W.1
  • 2
    • 33847032960 scopus 로고    scopus 로고
    • The mammalian epigenome
    • Bernstein B.E., et al. The mammalian epigenome. Cell 128 (2007) 669-681
    • (2007) Cell , vol.128 , pp. 669-681
    • Bernstein, B.E.1
  • 3
    • 15744397041 scopus 로고    scopus 로고
    • Chromatin remodeling complexes: strength in diversity, precision through specialization
    • Cairns B.R. Chromatin remodeling complexes: strength in diversity, precision through specialization. Curr. Opin. Genet. Dev. 15 (2005) 185-190
    • (2005) Curr. Opin. Genet. Dev. , vol.15 , pp. 185-190
    • Cairns, B.R.1
  • 4
    • 33947693747 scopus 로고    scopus 로고
    • On the use of the word 'epigenetic'
    • Ptashne M. On the use of the word 'epigenetic'. Curr. Biol. 17 (2007) R233-R236
    • (2007) Curr. Biol. , vol.17
    • Ptashne, M.1
  • 5
    • 15744401773 scopus 로고    scopus 로고
    • Eukaryotic cytosine methyltransferases
    • Goll M.G., and Bestor T.H. Eukaryotic cytosine methyltransferases. Annu. Rev. Biochem. 74 (2005) 481-514
    • (2005) Annu. Rev. Biochem. , vol.74 , pp. 481-514
    • Goll, M.G.1    Bestor, T.H.2
  • 6
    • 33847076248 scopus 로고    scopus 로고
    • Chromatin challenges during DNA replication and repair
    • Groth A., et al. Chromatin challenges during DNA replication and repair. Cell 128 (2007) 721-733
    • (2007) Cell , vol.128 , pp. 721-733
    • Groth, A.1
  • 7
    • 55549103314 scopus 로고    scopus 로고
    • A model for transmission of the H3K27me3 epigenetic mark
    • Hansen K.H., et al. A model for transmission of the H3K27me3 epigenetic mark. Nat. Cell Biol. 10 (2008) 1291-1300
    • (2008) Nat. Cell Biol. , vol.10 , pp. 1291-1300
    • Hansen, K.H.1
  • 8
    • 15044366201 scopus 로고    scopus 로고
    • Methylation of histones: playing memory with DNA
    • Peters A.H., and Schubeler D. Methylation of histones: playing memory with DNA. Curr. Opin. Cell Biol. 17 (2005) 230-238
    • (2005) Curr. Opin. Cell Biol. , vol.17 , pp. 230-238
    • Peters, A.H.1    Schubeler, D.2
  • 9
    • 34249337761 scopus 로고    scopus 로고
    • Perceptions of epigenetics
    • Bird A. Perceptions of epigenetics. Nature 447 (2007) 396-398
    • (2007) Nature , vol.447 , pp. 396-398
    • Bird, A.1
  • 10
    • 0033538531 scopus 로고    scopus 로고
    • Fundamentally different logic of gene regulation in eukaryotes and prokaryotes
    • Struhl K. Fundamentally different logic of gene regulation in eukaryotes and prokaryotes. Cell 98 (1999) 1-4
    • (1999) Cell , vol.98 , pp. 1-4
    • Struhl, K.1
  • 11
    • 0031707751 scopus 로고    scopus 로고
    • Alteration of nucleosome structure as a mechanism of transcriptional regulation
    • Workman J.L., and Kingston R.E. Alteration of nucleosome structure as a mechanism of transcriptional regulation. Annu. Rev. Biochem. 67 (1998) 545-579
    • (1998) Annu. Rev. Biochem. , vol.67 , pp. 545-579
    • Workman, J.L.1    Kingston, R.E.2
  • 12
    • 43449096915 scopus 로고    scopus 로고
    • Chromatin decouples promoter threshold from dynamic range
    • Lam F.H., et al. Chromatin decouples promoter threshold from dynamic range. Nature 453 (2008) 246-250
    • (2008) Nature , vol.453 , pp. 246-250
    • Lam, F.H.1
  • 13
    • 32444434989 scopus 로고    scopus 로고
    • Histone H4-K16 acetylation controls chromatin structure and protein interactions
    • Shogren-Knaak M., et al. Histone H4-K16 acetylation controls chromatin structure and protein interactions. Science 311 (2006) 844-847
    • (2006) Science , vol.311 , pp. 844-847
    • Shogren-Knaak, M.1
  • 14
    • 34848825691 scopus 로고    scopus 로고
    • Polycomb response elements mediate the formation of chromosome higher-order structures in the bithorax complex
    • Lanzuolo C., et al. Polycomb response elements mediate the formation of chromosome higher-order structures in the bithorax complex. Nat. Cell Biol. 9 (2007) 1167-1174
    • (2007) Nat. Cell Biol. , vol.9 , pp. 1167-1174
    • Lanzuolo, C.1
  • 15
    • 55349100420 scopus 로고    scopus 로고
    • Polycomb group proteins Ezh2 and Rnf2 direct genomic contraction and imprinted repression in early mouse embryos
    • Terranova R., et al. Polycomb group proteins Ezh2 and Rnf2 direct genomic contraction and imprinted repression in early mouse embryos. Dev. Cell 15 (2008) 668-679
    • (2008) Dev. Cell , vol.15 , pp. 668-679
    • Terranova, R.1
  • 16
    • 0035090476 scopus 로고    scopus 로고
    • Coincidence, coevolution, or causation? DNA content, cell size, and the C-value enigma
    • Gregory T.R. Coincidence, coevolution, or causation? DNA content, cell size, and the C-value enigma. Biol. Rev. Camb. Philos. Soc. 76 (2001) 65-101
    • (2001) Biol. Rev. Camb. Philos. Soc. , vol.76 , pp. 65-101
    • Gregory, T.R.1
  • 17
    • 0037385868 scopus 로고    scopus 로고
    • Cytosine methylation mediates sexual conflict
    • Bestor T.H. Cytosine methylation mediates sexual conflict. Trends Genet. 19 (2003) 185-190
    • (2003) Trends Genet. , vol.19 , pp. 185-190
    • Bestor, T.H.1
  • 18
    • 1542563409 scopus 로고    scopus 로고
    • Initial sequencing and comparative analysis of the mouse genome
    • Waterston R.H., et al. Initial sequencing and comparative analysis of the mouse genome. Nature 420 (2002) 520-562
    • (2002) Nature , vol.420 , pp. 520-562
    • Waterston, R.H.1
  • 19
    • 0042697343 scopus 로고    scopus 로고
    • The evolution of transcriptional regulation in eukaryotes
    • Wray G.A., et al. The evolution of transcriptional regulation in eukaryotes. Mol. Biol. Evol. 20 (2003) 1377-1419
    • (2003) Mol. Biol. Evol. , vol.20 , pp. 1377-1419
    • Wray, G.A.1
  • 20
    • 33746219660 scopus 로고    scopus 로고
    • The design of transcription-factor binding sites is affected by combinatorial regulation
    • Bilu Y., and Barkai N. The design of transcription-factor binding sites is affected by combinatorial regulation. Genome Biol. 6 (2005) R103
    • (2005) Genome Biol. , vol.6
    • Bilu, Y.1    Barkai, N.2
  • 21
    • 32044455298 scopus 로고    scopus 로고
    • Large-scale structure of genomic methylation patterns
    • Rollins R.A., et al. Large-scale structure of genomic methylation patterns. Genome Res. 16 (2006) 157-163
    • (2006) Genome Res. , vol.16 , pp. 157-163
    • Rollins, R.A.1
  • 22
    • 0028940587 scopus 로고
    • Gene number, noise reduction and biological complexity
    • Bird A.P. Gene number, noise reduction and biological complexity. Trends Genet. 11 (1995) 94-100
    • (1995) Trends Genet. , vol.11 , pp. 94-100
    • Bird, A.P.1
  • 23
    • 0036144048 scopus 로고    scopus 로고
    • DNA methylation patterns and epigenetic memory
    • Bird A. DNA methylation patterns and epigenetic memory. Genes Dev. 16 (2002) 6-21
    • (2002) Genes Dev. , vol.16 , pp. 6-21
    • Bird, A.1
  • 24
    • 0031662164 scopus 로고    scopus 로고
    • Transcription of IAP endogenous retroviruses is constrained by cytosine methylation
    • Walsh C.P., et al. Transcription of IAP endogenous retroviruses is constrained by cytosine methylation. Nat. Genet. 20 (1998) 116-117
    • (1998) Nat. Genet. , vol.20 , pp. 116-117
    • Walsh, C.P.1
  • 25
    • 34848812584 scopus 로고    scopus 로고
    • Polycomb Group proteins: an evolutionary perspective
    • Whitcomb S.J., et al. Polycomb Group proteins: an evolutionary perspective. Trends Genet. 23 (2007) 494-502
    • (2007) Trends Genet. , vol.23 , pp. 494-502
    • Whitcomb, S.J.1
  • 26
    • 0027141519 scopus 로고
    • Number of CpG islands and genes in human and mouse
    • Antequera F., and Bird A. Number of CpG islands and genes in human and mouse. Proc. Natl. Acad. Sci. U. S. A. 90 (1993) 11995-11999
    • (1993) Proc. Natl. Acad. Sci. U. S. A. , vol.90 , pp. 11995-11999
    • Antequera, F.1    Bird, A.2
  • 27
    • 0000617895 scopus 로고
    • Cytosine methylation: the pros and cons of DNA methylation
    • Bestor T.H., and Coxon A. Cytosine methylation: the pros and cons of DNA methylation. Curr. Biol. 3 (1993) 384-386
    • (1993) Curr. Biol. , vol.3 , pp. 384-386
    • Bestor, T.H.1    Coxon, A.2
  • 28
    • 34047116826 scopus 로고    scopus 로고
    • Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
    • Weber M., et al. Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat. Genet. 39 (2007) 457-466
    • (2007) Nat. Genet. , vol.39 , pp. 457-466
    • Weber, M.1
  • 29
    • 0023216891 scopus 로고
    • CpG islands in vertebrate genomes
    • Gardiner-Garden M., and Frommer M. CpG islands in vertebrate genomes. J. Mol. Biol. 196 (1987) 261-282
    • (1987) J. Mol. Biol. , vol.196 , pp. 261-282
    • Gardiner-Garden, M.1    Frommer, M.2
  • 30
    • 0037133565 scopus 로고    scopus 로고
    • Comprehensive analysis of CpG islands in human chromosomes 21 and 22
    • Takai D., and Jones P.A. Comprehensive analysis of CpG islands in human chromosomes 21 and 22. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 3740-3745
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 3740-3745
    • Takai, D.1    Jones, P.A.2
  • 31
    • 0033822364 scopus 로고    scopus 로고
    • Large-scale human promoter mapping using CpG islands
    • Ioshikhes I.P., and Zhang M.Q. Large-scale human promoter mapping using CpG islands. Nat. Genet. 26 (2000) 61-63
    • (2000) Nat. Genet. , vol.26 , pp. 61-63
    • Ioshikhes, I.P.1    Zhang, M.Q.2
  • 32
    • 33646472425 scopus 로고    scopus 로고
    • Mice and men: their promoter properties
    • Bajic V.B., et al. Mice and men: their promoter properties. PLoS Genet. 2 (2006) e54
    • (2006) PLoS Genet. , vol.2
    • Bajic, V.B.1
  • 33
    • 34248358308 scopus 로고    scopus 로고
    • Hyperconserved CpG domains underlie Polycomb-binding sites
    • Tanay A., et al. Hyperconserved CpG domains underlie Polycomb-binding sites. Proc. Natl. Acad. Sci. U. S. A. 104 (2007) 5521-5526
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 5521-5526
    • Tanay, A.1
  • 34
    • 36749017978 scopus 로고    scopus 로고
    • CG dinucleotide clustering is a species-specific property of the genome
    • Glass J.L., et al. CG dinucleotide clustering is a species-specific property of the genome. Nucleic Acids Res. 35 (2007) 6798-6807
    • (2007) Nucleic Acids Res. , vol.35 , pp. 6798-6807
    • Glass, J.L.1
  • 35
    • 43749098985 scopus 로고    scopus 로고
    • DNA methylation landscapes: provocative insights from epigenomics
    • Suzuki M.M., and Bird A. DNA methylation landscapes: provocative insights from epigenomics. Natl. Rev. 9 (2008) 465-476
    • (2008) Natl. Rev. , vol.9 , pp. 465-476
    • Suzuki, M.M.1    Bird, A.2
  • 36
    • 38649126918 scopus 로고    scopus 로고
    • Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation
    • Fouse S.D., et al. Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation. Cell Stem Cell 2 (2008) 160-169
    • (2008) Cell Stem Cell , vol.2 , pp. 160-169
    • Fouse, S.D.1
  • 37
    • 49649125042 scopus 로고    scopus 로고
    • Genome-scale DNA methylation maps of pluripotent and differentiated cells
    • Meissner A., et al. Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature 454 (2008) 766-770
    • (2008) Nature , vol.454 , pp. 766-770
    • Meissner, A.1
  • 38
    • 51649129596 scopus 로고    scopus 로고
    • Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors
    • Mohn F., et al. Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors. Mol. Cell 30 (2008) 755-766
    • (2008) Mol. Cell , vol.30 , pp. 755-766
    • Mohn, F.1
  • 39
    • 45349086923 scopus 로고    scopus 로고
    • Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes
    • Farthing C.R., et al. Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes. PLoS Genet. 4 (2008) e1000116
    • (2008) PLoS Genet. , vol.4
    • Farthing, C.R.1
  • 40
    • 38949212693 scopus 로고    scopus 로고
    • A novel CpG island set identifies tissue-specific methylation at developmental gene loci
    • Illingworth R., et al. A novel CpG island set identifies tissue-specific methylation at developmental gene loci. PLoS Biol. 6 (2008) e22
    • (2008) PLoS Biol. , vol.6
    • Illingworth, R.1
  • 41
    • 33751505540 scopus 로고    scopus 로고
    • DNA methylation profiling of human chromosomes 6, 20 and 22
    • Eckhardt F., et al. DNA methylation profiling of human chromosomes 6, 20 and 22. Nat. Genet. 38 (2006) 1378-1385
    • (2006) Nat. Genet. , vol.38 , pp. 1378-1385
    • Eckhardt, F.1
  • 42
    • 46449094276 scopus 로고    scopus 로고
    • Dissecting direct reprogramming through integrative genomic analysis
    • Mikkelsen T.S., et al. Dissecting direct reprogramming through integrative genomic analysis. Nature 454 (2008) 49-55
    • (2008) Nature , vol.454 , pp. 49-55
    • Mikkelsen, T.S.1
  • 43
    • 33744805985 scopus 로고    scopus 로고
    • Genome-wide analysis of mammalian promoter architecture and evolution
    • Carninci P., et al. Genome-wide analysis of mammalian promoter architecture and evolution. Nat. Genet. 38 (2006) 626-635
    • (2006) Nat. Genet. , vol.38 , pp. 626-635
    • Carninci, P.1
  • 44
    • 52449132322 scopus 로고    scopus 로고
    • Is there a code embedded in proteins that is based on post-translational modifications?
    • Sims III R.J., and Reinberg D. Is there a code embedded in proteins that is based on post-translational modifications?. Nat. Rev. Mol. Cell Biol. 9 (2008) 815-820
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 815-820
    • Sims III, R.J.1    Reinberg, D.2
  • 45
    • 35848961668 scopus 로고    scopus 로고
    • How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers
    • Taverna S.D., et al. How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers. Nat. Struct. Mol. Biol. 14 (2007) 1025-1040
    • (2007) Nat. Struct. Mol. Biol. , vol.14 , pp. 1025-1040
    • Taverna, S.D.1
  • 46
    • 23944462969 scopus 로고    scopus 로고
    • Genome-wide map of nucleosome acetylation and methylation in yeast
    • Pokholok D.K., et al. Genome-wide map of nucleosome acetylation and methylation in yeast. Cell 122 (2005) 517-527
    • (2005) Cell , vol.122 , pp. 517-527
    • Pokholok, D.K.1
  • 47
    • 2642570305 scopus 로고    scopus 로고
    • The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote
    • Schubeler D., et al. The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote. Genes Dev. 18 (2004) 1263-1271
    • (2004) Genes Dev. , vol.18 , pp. 1263-1271
    • Schubeler, D.1
  • 48
    • 38049054726 scopus 로고    scopus 로고
    • Genome-wide mapping and analysis of active promoters in mouse embryonic stem cells and adult organs
    • Barrera L.O., et al. Genome-wide mapping and analysis of active promoters in mouse embryonic stem cells and adult organs. Genome Res. 18 (2008) 46-59
    • (2008) Genome Res. , vol.18 , pp. 46-59
    • Barrera, L.O.1
  • 49
    • 34447098370 scopus 로고    scopus 로고
    • A chromatin landmark and transcription initiation at most promoters in human cells
    • Guenther M.G., et al. A chromatin landmark and transcription initiation at most promoters in human cells. Cell 130 (2007) 77-88
    • (2007) Cell , vol.130 , pp. 77-88
    • Guenther, M.G.1
  • 50
    • 14644406272 scopus 로고    scopus 로고
    • Active chromatin domains are defined by acetylation islands revealed by genome-wide mapping
    • Roh T.Y., et al. Active chromatin domains are defined by acetylation islands revealed by genome-wide mapping. Genes Dev. 19 (2005) 542-552
    • (2005) Genes Dev. , vol.19 , pp. 542-552
    • Roh, T.Y.1
  • 51
    • 34447098565 scopus 로고    scopus 로고
    • RNA polymerase II: just stopping by
    • Lorincz M.C., and Schubeler D. RNA polymerase II: just stopping by. Cell 130 (2007) 16-18
    • (2007) Cell , vol.130 , pp. 16-18
    • Lorincz, M.C.1    Schubeler, D.2
  • 52
    • 0000723156 scopus 로고    scopus 로고
    • Cloning of a mammalian transcriptional activator that binds unmethylated CpG motifs and shares a CXXC domain with DNA methyltransferase, human trithorax, and methyl-CpG binding domain protein 1
    • Voo K.S., et al. Cloning of a mammalian transcriptional activator that binds unmethylated CpG motifs and shares a CXXC domain with DNA methyltransferase, human trithorax, and methyl-CpG binding domain protein 1. Mol. Cell. Biol. 20 (2000) 2108-2121
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 2108-2121
    • Voo, K.S.1
  • 53
    • 34548603504 scopus 로고    scopus 로고
    • Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation
    • Jia D., et al. Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation. Nature 449 (2007) 248-251
    • (2007) Nature , vol.449 , pp. 248-251
    • Jia, D.1
  • 54
    • 34547725157 scopus 로고    scopus 로고
    • DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA
    • Ooi S.K., et al. DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA. Nature 448 (2007) 714-717
    • (2007) Nature , vol.448 , pp. 714-717
    • Ooi, S.K.1
  • 55
    • 54249099196 scopus 로고    scopus 로고
    • Species-specific transcription in mice carrying human chromosome 21
    • Wilson M.D., et al. Species-specific transcription in mice carrying human chromosome 21. Science 322 (2008) 434-438
    • (2008) Science , vol.322 , pp. 434-438
    • Wilson, M.D.1
  • 56
    • 33845799903 scopus 로고    scopus 로고
    • Polycomb silencing mechanisms and the management of genomic programmes
    • Schwartz Y.B., and Pirrotta V. Polycomb silencing mechanisms and the management of genomic programmes. Natl. Rev. 8 (2007) 9-22
    • (2007) Natl. Rev. , vol.8 , pp. 9-22
    • Schwartz, Y.B.1    Pirrotta, V.2
  • 57
    • 33847084602 scopus 로고    scopus 로고
    • Genome regulation by polycomb and trithorax proteins
    • Schuettengruber B., et al. Genome regulation by polycomb and trithorax proteins. Cell 128 (2007) 735-745
    • (2007) Cell , vol.128 , pp. 735-745
    • Schuettengruber, B.1
  • 58
    • 33646882068 scopus 로고    scopus 로고
    • Polycomb complexes repress developmental regulators in murine embryonic stem cells
    • Boyer L.A., et al. Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature 441 (2006) 349-353
    • (2006) Nature , vol.441 , pp. 349-353
    • Boyer, L.A.1
  • 59
    • 33646865180 scopus 로고    scopus 로고
    • Control of developmental regulators by Polycomb in human embryonic stem cells
    • Lee T.I., et al. Control of developmental regulators by Polycomb in human embryonic stem cells. Cell 125 (2006) 301-313
    • (2006) Cell , vol.125 , pp. 301-313
    • Lee, T.I.1
  • 60
    • 34249026300 scopus 로고    scopus 로고
    • High-resolution profiling of histone methylations in the human genome
    • Barski A., et al. High-resolution profiling of histone methylations in the human genome. Cell 129 (2007) 823-837
    • (2007) Cell , vol.129 , pp. 823-837
    • Barski, A.1
  • 61
    • 33646870495 scopus 로고    scopus 로고
    • Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions
    • Bracken A.P., et al. Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions. Genes Dev. 20 (2006) 1123-1136
    • (2006) Genes Dev. , vol.20 , pp. 1123-1136
    • Bracken, A.P.1
  • 62
    • 34547624303 scopus 로고    scopus 로고
    • Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
    • Mikkelsen T.S., et al. Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature 448 (2007) 553-560
    • (2007) Nature , vol.448 , pp. 553-560
    • Mikkelsen, T.S.1
  • 63
    • 34548434716 scopus 로고    scopus 로고
    • Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells
    • Pan G., et al. Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells. Cell Stem Cell 1 (2007) 299-312
    • (2007) Cell Stem Cell , vol.1 , pp. 299-312
    • Pan, G.1
  • 64
    • 34248169728 scopus 로고    scopus 로고
    • The polycomb group protein Suz12 is required for embryonic stem cell differentiation
    • Pasini D., et al. The polycomb group protein Suz12 is required for embryonic stem cell differentiation. Mol. Cell. Biol. 27 (2007) 3769-3779
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 3769-3779
    • Pasini, D.1
  • 65
    • 33750488431 scopus 로고    scopus 로고
    • The genomic landscape of histone modifications in human T cells
    • Roh T.Y., et al. The genomic landscape of histone modifications in human T cells. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 15782-15787
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 15782-15787
    • Roh, T.Y.1
  • 66
    • 33745604636 scopus 로고    scopus 로고
    • Suz12 binds to silenced regions of the genome in a cell-type-specific manner
    • Squazzo S.L., et al. Suz12 binds to silenced regions of the genome in a cell-type-specific manner. Genome Res. 16 (2006) 890-900
    • (2006) Genome Res. , vol.16 , pp. 890-900
    • Squazzo, S.L.1
  • 67
    • 47949125993 scopus 로고    scopus 로고
    • Polycomb complex 2 is required for E-cadherin repression by the Snail1 transcription factor
    • Herranz N., et al. Polycomb complex 2 is required for E-cadherin repression by the Snail1 transcription factor. Mol. Cell. Biol. 28 (2008) 4772-4781
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 4772-4781
    • Herranz, N.1
  • 68
    • 33646070846 scopus 로고    scopus 로고
    • A bivalent chromatin structure marks key developmental genes in embryonic stem cells
    • Bernstein B.E., et al. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125 (2006) 315-326
    • (2006) Cell , vol.125 , pp. 315-326
    • Bernstein, B.E.1
  • 69
    • 32044442759 scopus 로고    scopus 로고
    • Promoter features related to tissue specificity as measured by Shannon entropy
    • Schug J., et al. Promoter features related to tissue specificity as measured by Shannon entropy. Genome Biol. 6 (2005) R33
    • (2005) Genome Biol. , vol.6
    • Schug, J.1
  • 70
    • 33745258986 scopus 로고    scopus 로고
    • Genome-wide profiling of PRC1 and PRC2 polycomb chromatin binding in Drosophila melanogaster
    • Tolhuis B., et al. Genome-wide profiling of PRC1 and PRC2 polycomb chromatin binding in Drosophila melanogaster. Nat. Genet. 38 (2006) 694-699
    • (2006) Nat. Genet. , vol.38 , pp. 694-699
    • Tolhuis, B.1
  • 71
    • 43049085949 scopus 로고    scopus 로고
    • Differential H3K4 methylation identifies developmentally poised hematopoietic genes
    • Orford K., et al. Differential H3K4 methylation identifies developmentally poised hematopoietic genes. Dev. Cell 14 (2008) 798-809
    • (2008) Dev. Cell , vol.14 , pp. 798-809
    • Orford, K.1
  • 72
    • 33845295138 scopus 로고    scopus 로고
    • Human heterochromatin proteins form large domains containing KRAB-ZNF genes
    • Vogel M.J., et al. Human heterochromatin proteins form large domains containing KRAB-ZNF genes. Genome Res. 16 (2006) 1493-1504
    • (2006) Genome Res. , vol.16 , pp. 1493-1504
    • Vogel, M.J.1
  • 73
    • 57849109058 scopus 로고    scopus 로고
    • Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promoters
    • Core L.J., et al. Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promoters. Science 322 (2008) 1845-1848
    • (2008) Science , vol.322 , pp. 1845-1848
    • Core, L.J.1
  • 74
    • 57849105533 scopus 로고    scopus 로고
    • The antisense transcriptomes of human cells
    • He Y., et al. The antisense transcriptomes of human cells. Science 322 (2008) 1855-1857
    • (2008) Science , vol.322 , pp. 1855-1857
    • He, Y.1
  • 75
    • 57849123049 scopus 로고    scopus 로고
    • RNA exosome depletion reveals transcription upstream of active human promoters
    • Preker P., et al. RNA exosome depletion reveals transcription upstream of active human promoters. Science 322 (2008) 1851-1854
    • (2008) Science , vol.322 , pp. 1851-1854
    • Preker, P.1
  • 76
    • 57849140661 scopus 로고    scopus 로고
    • Divergent transcription from active promoters
    • Seila A.C., et al. Divergent transcription from active promoters. Science 322 (2008) 1849-1851
    • (2008) Science , vol.322 , pp. 1849-1851
    • Seila, A.C.1
  • 77
    • 33745549658 scopus 로고    scopus 로고
    • Epigenetic characterization of the early embryo with a chromatin immunoprecipitation protocol applicable to small cell populations
    • O'Neill L.P., et al. Epigenetic characterization of the early embryo with a chromatin immunoprecipitation protocol applicable to small cell populations. Nat. Genet. 38 (2006) 835-841
    • (2006) Nat. Genet. , vol.38 , pp. 835-841
    • O'Neill, L.P.1
  • 78
    • 40749109894 scopus 로고    scopus 로고
    • Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning
    • Cokus S.J., et al. Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning. Nature 452 (2008) 215-219
    • (2008) Nature , vol.452 , pp. 215-219
    • Cokus, S.J.1
  • 79
    • 33847037497 scopus 로고    scopus 로고
    • Noncoding RNAs and gene silencing
    • Zaratiegui M., et al. Noncoding RNAs and gene silencing. Cell 128 (2007) 763-776
    • (2007) Cell , vol.128 , pp. 763-776
    • Zaratiegui, M.1
  • 80
    • 33645469482 scopus 로고    scopus 로고
    • Stem cells and their niches
    • Moore K.A., and Lemischka I.R. Stem cells and their niches. Science 311 (2006) 1880-1885
    • (2006) Science , vol.311 , pp. 1880-1885
    • Moore, K.A.1    Lemischka, I.R.2
  • 81
    • 53549123008 scopus 로고    scopus 로고
    • Nature, nurture, or chance: stochastic gene expression and its consequences
    • Raj A., and van Oudenaarden A. Nature, nurture, or chance: stochastic gene expression and its consequences. Cell 135 (2008) 216-226
    • (2008) Cell , vol.135 , pp. 216-226
    • Raj, A.1    van Oudenaarden, A.2
  • 82
    • 0027328684 scopus 로고
    • Spatial segregation of odorant receptor expression in the mammalian olfactory epithelium
    • Vassar R., et al. Spatial segregation of odorant receptor expression in the mammalian olfactory epithelium. Cell 74 (1993) 309-318
    • (1993) Cell , vol.74 , pp. 309-318
    • Vassar, R.1
  • 83
    • 44349162752 scopus 로고    scopus 로고
    • Transcriptome-wide noise controls lineage choice in mammalian progenitor cells
    • Chang H.H., et al. Transcriptome-wide noise controls lineage choice in mammalian progenitor cells. Nature 453 (2008) 544-547
    • (2008) Nature , vol.453 , pp. 544-547
    • Chang, H.H.1
  • 84
    • 37549002155 scopus 로고    scopus 로고
    • Nanog safeguards pluripotency and mediates germline development
    • Chambers I., et al. Nanog safeguards pluripotency and mediates germline development. Nature 450 (2007) 1230-1234
    • (2007) Nature , vol.450 , pp. 1230-1234
    • Chambers, I.1
  • 85
    • 53049092465 scopus 로고    scopus 로고
    • Dynamic equilibrium and heterogeneity of mouse pluripotent stem cells with distinct functional and epigenetic states
    • Hayashi K., et al. Dynamic equilibrium and heterogeneity of mouse pluripotent stem cells with distinct functional and epigenetic states. Cell Stem Cell 3 (2008) 391-401
    • (2008) Cell Stem Cell , vol.3 , pp. 391-401
    • Hayashi, K.1
  • 86
    • 55549119925 scopus 로고    scopus 로고
    • Epigenetic restriction of embryonic cell lineage fate by methylation of Elf5
    • Ng R.K., et al. Epigenetic restriction of embryonic cell lineage fate by methylation of Elf5. Nat. Cell Biol. 10 (2008) 1280-1290
    • (2008) Nat. Cell Biol. , vol.10 , pp. 1280-1290
    • Ng, R.K.1
  • 87
    • 11144358198 scopus 로고    scopus 로고
    • A gene atlas of the mouse and human protein-encoding transcriptomes
    • Su A.I., et al. A gene atlas of the mouse and human protein-encoding transcriptomes. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 6062-6067
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 6062-6067
    • Su, A.I.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.