-
1
-
-
10744230436
-
A Suv39h-dependent mechanism for silencing S-phase genes in differentiating but not in cycling cells
-
Ait-Si-Ali S. Guasconi V, Fritsch L, Yahi H. Sekhri R, Naguibneva I. Robin P, Cabon F, Polesskaya A, Harel-Bellan A. 2004. A Suv39h-dependent mechanism for silencing S-phase genes in differentiating but not in cycling cells. Embo J 23:605-615.
-
(2004)
Embo J
, vol.23
, pp. 605-615
-
-
Ait-Si-Ali, S.1
Guasconi, V.2
Fritsch, L.3
Yahi, H.4
Sekhri, R.5
Naguibneva, I.6
Robin, P.7
Cabon, F.8
Polesskaya, A.9
Harel-Bellan, A.10
-
2
-
-
0242412318
-
Retinoblastoma tumor suppressor: Analyses of dynamic behavior in living cells reveal multiple modes of regulation
-
Angus SP, Solomon DA, Kuschel L, Hennigan RF, Knudsen ES. 2003. Retinoblastoma tumor suppressor: Analyses of dynamic behavior in living cells reveal multiple modes of regulation. Mol Cell Biol 23:8172-8188.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 8172-8188
-
-
Angus, S.P.1
Solomon, D.A.2
Kuschel, L.3
Hennigan, R.F.4
Knudsen, E.S.5
-
3
-
-
0035930750
-
Requirement of heterochromatin for cohesion at centromeres
-
Bernard P, Maure JF, Partridge JF, Genier S, Javerzat JP, Allshire RC. 2001. Requirement of heterochromatin for cohesion at centromeres. Science 294:2539-2542.
-
(2001)
Science
, vol.294
, pp. 2539-2542
-
-
Bernard, P.1
Maure, J.F.2
Partridge, J.F.3
Genier, S.4
Javerzat, J.P.5
Allshire, R.C.6
-
4
-
-
15044339763
-
Differential role of RB in response to UV and IR damage
-
Bosco EE, Knudsen ES. 2005. Differential role of RB in response to UV and IR damage. Nucleic Acids Res 33:1581-1592.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 1581-1592
-
-
Bosco, E.E.1
Knudsen, E.S.2
-
5
-
-
0032484989
-
Retinoblastoma protein recruits histone deacetylase to repress transcription
-
Brehm A, Miska EA, McCance DJ, Reld JL, Bannister AJ, Kouzarides T. 1998. Retinoblastoma protein recruits histone deacetylase to repress transcription. Nature 391:597-601.
-
(1998)
Nature
, vol.391
, pp. 597-601
-
-
Brehm, A.1
Miska, E.A.2
McCance, D.J.3
Reld, J.L.4
Bannister, A.J.5
Kouzarides, T.6
-
6
-
-
0348150714
-
Maintenance of stable heterochromatin domains by dynamic HP1 binding
-
Cheutin T, McNairn AJ, Jenuwein T, Gilbert DM, Singh PB, Misteli T. 2003. Maintenance of stable heterochromatin domains by dynamic HP1 binding. Science 299:721-725.
-
(2003)
Science
, vol.299
, pp. 721-725
-
-
Cheutin, T.1
McNairn, A.J.2
Jenuwein, T.3
Gilbert, D.M.4
Singh, P.B.5
Misteli, T.6
-
7
-
-
18344383345
-
Pocket proteins and cell cycle control
-
Cobrinik D. 2005. Pocket proteins and cell cycle control. Oncogene 24:2796-2809.
-
(2005)
Oncogene
, vol.24
, pp. 2796-2809
-
-
Cobrinik, D.1
-
8
-
-
0028060515
-
The retinoblastoma protein and BRGI formacomplex and cooperate to induce cell cycle arrest
-
Dunaief JL, Strober BE, Guha S, Khavari PA, Alin K, Luban J, Begemann M, Crabtree GR, Goff SP. 1994. The retinoblastoma protein and BRGI formacomplex and cooperate to induce cell cycle arrest. Cell 79:119-130.
-
(1994)
Cell
, vol.79
, pp. 119-130
-
-
Dunaief, J.L.1
Strober, B.E.2
Guha, S.3
Khavari, P.A.4
Alin, K.5
Luban, J.6
Begemann, M.7
Crabtree, G.R.8
Goff, S.P.9
-
9
-
-
20144388146
-
Loss of acetylation at Lys 16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer
-
Fraga MF, Ballestar E, Villar-Garea A, Boix-Chornet M, Espada J, SchottaG, Bonaldi T, Haydon C, Ropero S, Petrie K, Iyer NG, Perez-Rosado A, Calvo E, Lopez JA, Cano A, Calasanz MJ, Colomer D, Piris MA, Ahn N, Imhof A, Caldas C, Jenuwein T, Esteller M. 2005. Loss of acetylation at Lys 16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer. Nat Genet 37:391-400.
-
(2005)
Nat Genet
, vol.37
, pp. 391-400
-
-
Fraga, M.F.1
Ballestar, E.2
Villar-Garea, A.3
Boix-Chornet, M.4
Espada, J.5
Schotta, G.6
Bonaldi, T.7
Haydon, C.8
Ropero, S.9
Petrie, K.10
Iyer, N.G.11
Perez-Rosado, A.12
Calvo, E.13
Lopez, J.A.14
Cano, A.15
Calasanz, M.J.16
Colomer, D.17
Piris, M.A.18
Ahn, N.19
Imhof, A.20
Caldas, C.21
Jenuwein, T.22
Esteller, M.23
more..
-
10
-
-
20244376464
-
Role of the RBI family in stabilizing histone methylation at constitutive heterochromatin
-
Gonzalo S, Garcia-Cao M, Fraga MF, Schotta G, Peters AH, Cotter SE, Eguia R, Dean DC, Esteller M, Jenuwein T, Blasco MA. 2005. Role of the RBI family in stabilizing histone methylation at constitutive heterochromatin. Nat Cell Biol 7:420-428.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 420-428
-
-
Gonzalo, S.1
Garcia-Cao, M.2
Fraga, M.F.3
Schotta, G.4
Peters, A.H.5
Cotter, S.E.6
Eguia, R.7
Dean, D.C.8
Esteller, M.9
Jenuwein, T.10
Blasco, M.A.11
-
11
-
-
0042528729
-
Heterochromatin and epigenetic control of gene expression
-
Grewal SI, Moazed D. 2003. Heterochromatin and epigenetic control of gene expression. Science 301:798-802.
-
(2003)
Science
, vol.301
, pp. 798-802
-
-
Grewal, S.I.1
Moazed, D.2
-
12
-
-
0037422606
-
RNA interference machinery regulates chromosome dynamics during mitosis and meiosis in fission yeast
-
Hall IM, Noma K, Grewal SI. 2003. RNA interference machinery regulates chromosome dynamics during mitosis and meiosis in fission yeast. Proc Natl Acad Sci USA 100:193-198.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 193-198
-
-
Hall, I.M.1
Noma, K.2
Grewal, S.I.3
-
13
-
-
0033578816
-
Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through GI
-
Harbour J W, Luo RX, Dei Santi A, Postigo AA, Dean DC. 1999. Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through GI. Cell 98:859-869.
-
(1999)
Cell
, vol.98
, pp. 859-869
-
-
Harbour, J.W.1
Luo, R.X.2
Dei Santi, A.3
Postigo, A.A.4
Dean, D.C.5
-
14
-
-
0027426917
-
Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation
-
Helin K, Wu CL, Fattaey AR, Lees JA, Dynlacht BD, Ngwu C, Harlow E. 1993. Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation. Genes Dev 7:1850-1861.
-
(1993)
Genes Dev
, vol.7
, pp. 1850-1861
-
-
Helin, K.1
Wu, C.L.2
Fattaey, A.R.3
Lees, J.A.4
Dynlacht, B.D.5
Ngwu, C.6
Harlow, E.7
-
15
-
-
0029909105
-
Increased histone H1 phosphorylation and relaxed chromatin structure in Rb-deficient fibroblasts
-
Herrera RE, Chen F, Weinberg RA. 1996. Increased histone H1 phosphorylation and relaxed chromatin structure in Rb-deficient fibroblasts. Proc Natl Acad Sci USA 93:11510-11515.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 11510-11515
-
-
Herrera, R.E.1
Chen, F.2
Weinberg, R.A.3
-
16
-
-
33646250688
-
The Retinoblastoma Protein Regulates Pericentric Heterochromatin
-
Isaac CE, Francis SM, Martens AL, Julian LM, Seifried LA, Erdmann N, Binné UK, Harrington L, Sicinski P, Bérubé NG, Dyson NJ, Dick FA. 2006. The Retinoblastoma Protein Regulates Pericentric Heterochromatin. Mol Cell Biol 26:3659-3671.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 3659-3671
-
-
Isaac, C.E.1
Francis, S.M.2
Martens, A.L.3
Julian, L.M.4
Seifried, L.A.5
Erdmann, N.6
Binné, U.K.7
Harrington, L.8
Sicinski, P.9
Bérubé, N.G.10
Dyson, N.J.11
Dick, F.A.12
-
17
-
-
0035954427
-
Kinetics of core histones in living human cells: Little exchange of H3 and H4 and some rapid exchange of H2B
-
Kimura H. Cook PR. 2001. Kinetics of core histones in living human cells: Little exchange of H3 and H4 and some rapid exchange of H2B. J Cell Biol 153:1341-1353.
-
(2001)
J Cell Biol
, vol.153
, pp. 1341-1353
-
-
Kimura, H.1
Cook, P.R.2
-
18
-
-
0032549001
-
Rb interacts with histone deacetylase to repress transcription
-
Luo RX, Postigo AA, Dean DC. 1998. Rb interacts with histone deacetylase to repress transcription. Cell 92:463-473.
-
(1998)
Cell
, vol.92
, pp. 463-473
-
-
Luo, R.X.1
Postigo, A.A.2
Dean, D.C.3
-
19
-
-
0032484904
-
Retinoblastoma protein represses transcription by recruiting a histone deacetylase
-
Magnaghi-Jaulin L, Groisman R, Naguibneva I, Robin P, Lorain S, Le Villain JP, Troalen F, Trouche D, Harel-Bellan A. 1998. Retinoblastoma protein represses transcription by recruiting a histone deacetylase. Nature 391:601-605.
-
(1998)
Nature
, vol.391
, pp. 601-605
-
-
Magnaghi-Jaulin, L.1
Groisman, R.2
Naguibneva, I.3
Robin, P.4
Lorain, S.5
Le Villain, J.P.6
Troalen, F.7
Trouche, D.8
Harel-Bellan, A.9
-
20
-
-
1842733449
-
HPI and the dynamics of heterochromatin maintenance
-
Maison C, Almouzni G. 2004. HPI and the dynamics of heterochromatin maintenance. Nat Rev Mol Cell Biol 5:296-304.
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 296-304
-
-
Maison, C.1
Almouzni, G.2
-
21
-
-
0034656212
-
Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum
-
Marino S, Vooijs M, van Der Gulden H, Jonkers J, Berns A. 2000. Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum. Genes Dev 14:994-1004.
-
(2000)
Genes Dev
, vol.14
, pp. 994-1004
-
-
Marino, S.1
Vooijs, M.2
van Der Gulden, H.3
Jonkers, J.4
Berns, A.5
-
22
-
-
4444328464
-
Analysis of RB action in DNA damage checkpoint response
-
Mayhew CN, Bosco EE, Solomon DA, Knudsen ES, Angus SP. 2004. Analysis of RB action in DNA damage checkpoint response. Methods Mol Biol 281:3-16.
-
(2004)
Methods Mol Biol
, vol.281
, pp. 3-16
-
-
Mayhew, C.N.1
Bosco, E.E.2
Solomon, D.A.3
Knudsen, E.S.4
Angus, S.P.5
-
23
-
-
0037667702
-
Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence
-
Narita M, Nunez S, Heard E, Narita M, Lin AW, Hearn SA, Spector DL, Hannon GJ, Lowe SW. 2003. Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. Cell 113:703-716.
-
(2003)
Cell
, vol.113
, pp. 703-716
-
-
Narita, M.1
Nunez, S.2
Heard, E.3
Narita, M.4
Lin, A.W.5
Hearn, S.A.6
Spector, D.L.7
Hannon, G.J.8
Lowe, S.W.9
-
24
-
-
0037371661
-
Balance between acetylation and methylation of histone H3 lysine 9 on the E2F-responsive dihydrofolate reductase promoter
-
Nicolas E, Roumillac C, Trouche D. 2003. Balance between acetylation and methylation of histone H3 lysine 9 on the E2F-responsive dihydrofolate reductase promoter. Mol Cell Biol 23:1614-1622.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 1614-1622
-
-
Nicolas, E.1
Roumillac, C.2
Trouche, D.3
-
25
-
-
0035797384
-
Rb targets histone H3 methylation and HPI to promoters
-
Nielsen SJ,Schneider R, Bauer UM, Bannister AJ, Morrison A, O'Carroll D, Firestein R, Cleary M, Jenuwein T, Herrera RE, Kouzarides T. 2001. Rb targets histone H3 methylation and HPI to promoters. Nature 412:561-565.
-
(2001)
Nature
, vol.412
, pp. 561-565
-
-
Nielsen, S.J.1
Schneider, R.2
Bauer, U.M.3
Bannister, A.J.4
Morrison, A.5
O'Carroll, D.6
Firestein, R.7
Cleary, M.8
Jenuwein, T.9
Herrera, R.E.10
Kouzarides, T.11
-
26
-
-
0036144420
-
Recruitment of cohesin to heterochromatic regions by Swi6/HPI in fission yeast
-
Nonaka N, Kitajima T, Yokobayashi S, Xiao G, Yamamoto M, Grewal SI, Watanabe Y. 2002. Recruitment of cohesin to heterochromatic regions by Swi6/HPI in fission yeast. Nat Cell Biol 4:89-93.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 89-93
-
-
Nonaka, N.1
Kitajima, T.2
Yokobayashi, S.3
Xiao, G.4
Yamamoto, M.5
Grewal, S.I.6
Watanabe, Y.7
-
27
-
-
17944380227
-
Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability
-
Peters AH, O'Carroll D, Scherthan H, Mechtler K, Sauer S, Schofer C, Weipoltshammer K, Pagani M, Lachner M, Kohlmaier A, Opravil S, Doyle M, Sibilia M, Jenuwein T. 2001. Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability. Cell 107:323-337.
-
(2001)
Cell
, vol.107
, pp. 323-337
-
-
Peters, A.H.1
O'Carroll, D.2
Scherthan, H.3
Mechtler, K.4
Sauer, S.5
Schofer, C.6
Weipoltshammer, K.7
Pagani, M.8
Lachner, M.9
Kohlmaier, A.10
Opravil, S.11
Doyle, M.12
Sibilia, M.13
Jenuwein, T.14
-
28
-
-
0034632829
-
Regulation of chromatin structure by site-specific histone H3 methyltransferases
-
Rea S. Eisenhaber F, O'Carroll D, Strahl BD, Sun ZW, Schmid M, Opravil S, Mechtler K, Ponting CP, Allis CD, Jenuwein T. 2000. Regulation of chromatin structure by site-specific histone H3 methyltransferases. Nature 406:593-599.
-
(2000)
Nature
, vol.406
, pp. 593-599
-
-
Rea, S.1
Eisenhaber, F.2
O'Carroll, D.3
Strahl, B.D.4
Sun, Z.W.5
Schmid, M.6
Opravil, S.7
Mechtler, K.8
Ponting, C.P.9
Allis, C.D.10
Jenuwein, T.11
-
29
-
-
2642542643
-
A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin
-
Schotta G, Lachner M, Sarma K, Ebert A, Sengupta R. Reuter G, Reinberg D. Jenuwein T. 2004. A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin. Genes Dev 18:1251-1262.
-
(2004)
Genes Dev
, vol.18
, pp. 1251-1262
-
-
Schotta, G.1
Lachner, M.2
Sarma, K.3
Ebert, A.4
Sengupta, R.5
Reuter, G.6
Reinberg, D.7
Jenuwein, T.8
-
30
-
-
0030069682
-
Disruption of RB/E2F-1 interaction by single point mutations in E2F-1 enhances S-phase entry and apoptosis
-
Shan B, Durfee T, Lee WH. 1996. Disruption of RB/E2F-1 interaction by single point mutations in E2F-1 enhances S-phase entry and apoptosis. Proc Natl Acad Sci USA 93:679-684.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 679-684
-
-
Shan, B.1
Durfee, T.2
Lee, W.H.3
-
31
-
-
0029849620
-
Cancer cell cycles
-
Sherr CJ. 1996. Cancer cell cycles. Science 274:1672-1677.
-
(1996)
Science
, vol.274
, pp. 1672-1677
-
-
Sherr, C.J.1
-
32
-
-
0142123190
-
Histone deacetylation of RB-responsive promoters: Requisite for specific gene repression but dispensable for cell cycle inhibition
-
Siddiqui H, Solomon DA, Gunawardena RW, Wang Y, Knudsen ES. 2003. Histone deacetylation of RB-responsive promoters: Requisite for specific gene repression but dispensable for cell cycle inhibition. Mol Cell Biol 23:7719-7731.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 7719-7731
-
-
Siddiqui, H.1
Solomon, D.A.2
Gunawardena, R.W.3
Wang, Y.4
Knudsen, E.S.5
-
33
-
-
0028986413
-
A role for retinoblastoma protein in potentiating transcriptional activation by the glucocorticoid receptor
-
Singh P, Coe J, Hong W. 1995. A role for retinoblastoma protein in potentiating transcriptional activation by the glucocorticoid receptor. Nature 374:562-565.
-
(1995)
Nature
, vol.374
, pp. 562-565
-
-
Singh, P.1
Coe, J.2
Hong, W.3
-
34
-
-
0034608823
-
BRG-1 is required for RB-mediated cell cycle arrest
-
Strobeck MW, Knudsen KE, Fribourg AF, DeCristofaro MF, Weissman BE, Imbalzano AN, Knudsen ES. 2000. BRG-1 is required for RB-mediated cell cycle arrest. Proc Natl Acad Sci USA 97:7748-7753.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 7748-7753
-
-
Strobeck, M.W.1
Knudsen, K.E.2
Fribourg, A.F.3
DeCristofaro, M.F.4
Weissman, B.E.5
Imbalzano, A.N.6
Knudsen, E.S.7
-
35
-
-
0034737290
-
Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF
-
Zhang HS, Gavin M, Dahiya A, Postigo AA, Ma D, Luo RX, Harbour J W, Dean DC. 2000. Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF. Cell 101:79-89.
-
(2000)
Cell
, vol.101
, pp. 79-89
-
-
Zhang, H.S.1
Gavin, M.2
Dahiya, A.3
Postigo, A.A.4
Ma, D.5
Luo, R.X.6
Harbour, J.W.7
Dean, D.C.8
|