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Volumn 8, Issue 4, 2009, Pages 532-535

Balancing the decision of cell proliferation and cell fate

Author keywords

Apoptosis; E2F1; Microarray; PI3K; Proliferation

Indexed keywords

PROTEIN P53; TRANSCRIPTION FACTOR E2F; TRANSCRIPTION FACTOR E2F1;

EID: 61449249141     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.8.4.7609     Document Type: Review
Times cited : (96)

References (60)
  • 1
    • 50149108858 scopus 로고    scopus 로고
    • Conserved functions of the pRB and E2F families
    • van den Heuvel S, Dyson N. Conserved functions of the pRB and E2F families. Nat Rev Mol Cell Biol 2008; 9:713-24.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 713-724
    • van den Heuvel, S.1    Dyson, N.2
  • 2
    • 36749050812 scopus 로고    scopus 로고
    • Life and death decisions by the E2F transcription factors
    • Iaquinta PJ, Lees JA. Life and death decisions by the E2F transcription factors. Curr Opin Cell Biol 2007; 19:649-57.
    • (2007) Curr Opin Cell Biol , vol.19 , pp. 649-657
    • Iaquinta, P.J.1    Lees, J.A.2
  • 3
    • 33750920705 scopus 로고    scopus 로고
    • Distinct and overlapping roles for E2F family members in transcription, proliferation and apoptosis
    • DeGregori J, Johnson DG. Distinct and overlapping roles for E2F family members in transcription, proliferation and apoptosis. Curr Mol Med 2006; 6:739-48.
    • (2006) Curr Mol Med , vol.6 , pp. 739-748
    • DeGregori, J.1    Johnson, D.G.2
  • 4
    • 0027491775 scopus 로고
    • Expression of transcription factor E2F1 induces quiescent cells to enter S phase
    • Johnson DG, Schwarz JK, Cress WD, Nevins JR. Expression of transcription factor E2F1 induces quiescent cells to enter S phase. Nature 1993; 365:349-52.
    • (1993) Nature , vol.365 , pp. 349-352
    • Johnson, D.G.1    Schwarz, J.K.2    Cress, W.D.3    Nevins, J.R.4
  • 5
    • 0032528027 scopus 로고    scopus 로고
    • E2F3 activity is regulated during the cell cycle and is required for the induction of S phase
    • Leone G, DeGregori J, Yan Z, Jakoi L, Ishida S, Williams RS, et al. E2F3 activity is regulated during the cell cycle and is required for the induction of S phase. Genes Dev 1998; 12:2120-30.
    • (1998) Genes Dev , vol.12 , pp. 2120-2130
    • Leone, G.1    DeGregori, J.2    Yan, Z.3    Jakoi, L.4    Ishida, S.5    Williams, R.S.6
  • 6
    • 33846283395 scopus 로고    scopus 로고
    • Compensation and specificity of function within the E2F family
    • Kong L-J, Chang JT, Bild AH, Nevins JR. Compensation and specificity of function within the E2F family. Oncogene 2007; 26:321-7.
    • (2007) Oncogene , vol.26 , pp. 321-327
    • Kong, L.-J.1    Chang, J.T.2    Bild, A.H.3    Nevins, J.R.4
  • 7
    • 17944375816 scopus 로고    scopus 로고
    • Myc requires distinct E2F activities to induce S phase and apoptosis
    • Leone G, Sears R, Huang E, Rempel R, Nuckolls F, Park C-H, et al. Myc requires distinct E2F activities to induce S phase and apoptosis. Mol Cell 2001; 8:105-13.
    • (2001) Mol Cell , vol.8 , pp. 105-113
    • Leone, G.1    Sears, R.2    Huang, E.3    Rempel, R.4    Nuckolls, F.5    Park, C.-H.6
  • 8
    • 0027403342 scopus 로고
    • A protein synthesis-dependent increase in E2F1 mRNA correlates with growth regulation of the dihydrofolate reductase promoter
    • Slansky JE, Li Y, Kaelin WG, Farnham PJ. A protein synthesis-dependent increase in E2F1 mRNA correlates with growth regulation of the dihydrofolate reductase promoter. Mol Cell Biol 1993; 13:1610-8.
    • (1993) Mol Cell Biol , vol.13 , pp. 1610-1618
    • Slansky, J.E.1    Li, Y.2    Kaelin, W.G.3    Farnham, P.J.4
  • 9
    • 0028364529 scopus 로고
    • Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression
    • Johnson DG, Ohtani K, Nevins JR. Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression. Genes Dev 1994; 8:1514-25.
    • (1994) Genes Dev , vol.8 , pp. 1514-1525
    • Johnson, D.G.1    Ohtani, K.2    Nevins, J.R.3
  • 10
    • 0032549001 scopus 로고    scopus 로고
    • Rb interacts with histone deacetylase to repress transcription
    • Luo RX, Postigo AA, Dean DC. Rb interacts with histone deacetylase to repress transcription. Cell 1998; 92:463-73.
    • (1998) Cell , vol.92 , pp. 463-473
    • Luo, R.X.1    Postigo, A.A.2    Dean, D.C.3
  • 11
  • 12
    • 0033564697 scopus 로고    scopus 로고
    • CDK inhibitors: Positive and negative regulators of G1-phase progression
    • Sherr CJ, Roberts JM. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev 1999; 13:1501-12.
    • (1999) Genes Dev , vol.13 , pp. 1501-1512
    • Sherr, C.J.1    Roberts, J.M.2
  • 13
    • 12344257683 scopus 로고    scopus 로고
    • DNA tumor viruses - the spies who lyse us
    • O'Shea CC. DNA tumor viruses - the spies who lyse us. Curr Opin Genet Dev 2005; 15:18-26.
    • (2005) Curr Opin Genet Dev , vol.15 , pp. 18-26
    • O'Shea, C.C.1
  • 14
    • 0141927097 scopus 로고    scopus 로고
    • pRB contains an E2F1-specific binding domain that allows E2F1-induced apoptosis to be regulated separately from other E2F activities
    • Dick FA, Dyson N. pRB contains an E2F1-specific binding domain that allows E2F1-induced apoptosis to be regulated separately from other E2F activities. Mol Cell 2003; 12:639-49.
    • (2003) Mol Cell , vol.12 , pp. 639-649
    • Dick, F.A.1    Dyson, N.2
  • 15
    • 0028222124 scopus 로고
    • p53 and E2F-1 cooperate to mediate apoptosis
    • Wu X, Levine AJ. p53 and E2F-1 cooperate to mediate apoptosis. Proc Natl Acad Sci USA 1994; 91:3602-6.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3602-3606
    • Wu, X.1    Levine, A.J.2
  • 17
    • 0141814666 scopus 로고    scopus 로고
    • Specificity in the activation and control of transcription factor E2F-dependent apoptosis
    • Hallstrom TC, Nevins JR. Specificity in the activation and control of transcription factor E2F-dependent apoptosis. Proc Natl Acad Sci USA 2003; 100:10848-53.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 10848-10853
    • Hallstrom, T.C.1    Nevins, J.R.2
  • 18
    • 23744507860 scopus 로고    scopus 로고
    • E2F1 is crucial for E2F-dependent apoptosis
    • Denchi EL, Helin K. E2F1 is crucial for E2F-dependent apoptosis. EMBO Rep 2005; 6:661-8.
    • (2005) EMBO Rep , vol.6 , pp. 661-668
    • Denchi, E.L.1    Helin, K.2
  • 19
    • 0035252592 scopus 로고    scopus 로고
    • E2Fs regulate the expression of genes involved in differentiation, development, proliferation and apoptosis
    • Muller H, Bracken AP, Vernell R, Moroni MC, Christians F, Grassilli E, et al. E2Fs regulate the expression of genes involved in differentiation, development, proliferation and apoptosis. Genes Dev 2001; 15:267-85.
    • (2001) Genes Dev , vol.15 , pp. 267-285
    • Muller, H.1    Bracken, A.P.2    Vernell, R.3    Moroni, M.C.4    Christians, F.5    Grassilli, E.6
  • 20
    • 0034949169 scopus 로고    scopus 로고
    • Role for E2F in the control of both DNA replication and mitotic functions as revealed from DNA microarray analysis
    • Ishida S, Huang E, Zuzan H, Spang R, Leone G, West M, et al. Role for E2F in the control of both DNA replication and mitotic functions as revealed from DNA microarray analysis. Mol Cell Biol 2001; 21:4684-99.
    • (2001) Mol Cell Biol , vol.21 , pp. 4684-4699
    • Ishida, S.1    Huang, E.2    Zuzan, H.3    Spang, R.4    Leone, G.5    West, M.6
  • 21
    • 85047699837 scopus 로고    scopus 로고
    • E2Fs upregulate expression of genes involved in DNA replication, DNA repair and mitosis
    • Polager S, Kalma Y, Berkovich E, Ginsberg D. E2Fs upregulate expression of genes involved in DNA replication, DNA repair and mitosis. Oncogene 2002; 21:437-46.
    • (2002) Oncogene , vol.21 , pp. 437-446
    • Polager, S.1    Kalma, Y.2    Berkovich, E.3    Ginsberg, D.4
  • 22
  • 23
    • 0033450933 scopus 로고    scopus 로고
    • A role for E2F1 in the induction of ARF, p53 and apoptosis during thymic negative selection
    • Zhu JW, DeRyckere D, Li FX, Wan YY, DeGregori J. A role for E2F1 in the induction of ARF, p53 and apoptosis during thymic negative selection. Cell Growth Differ 1999; 10:829-38.
    • (1999) Cell Growth Differ , vol.10 , pp. 829-838
    • Zhu, J.W.1    DeRyckere, D.2    Li, F.X.3    Wan, Y.Y.4    DeGregori, J.5
  • 26
    • 0034609864 scopus 로고    scopus 로고
    • A common E2F-1 and p73 pathway mediates cell death induced by TCR activation
    • Lissy NA, Davis PK, Irwin M, Kaelin WG, Dowdy SF. A common E2F-1 and p73 pathway mediates cell death induced by TCR activation. Nature 2000; 407:642-4.
    • (2000) Nature , vol.407 , pp. 642-644
    • Lissy, N.A.1    Davis, P.K.2    Irwin, M.3    Kaelin, W.G.4    Dowdy, S.F.5
  • 27
    • 0033666776 scopus 로고    scopus 로고
    • Role of the p53 homologue p73 in E2F1-induced apoptosis
    • Stiewe T, Putzer BM. Role of the p53 homologue p73 in E2F1-induced apoptosis. Nat Genet 2000; 26:464-9.
    • (2000) Nat Genet , vol.26 , pp. 464-469
    • Stiewe, T.1    Putzer, B.M.2
  • 30
    • 33747364011 scopus 로고    scopus 로고
    • Bcl-2-related ovarian killer, is cell cycle-regulated and sensitizes to stress-induced apoptosis
    • Rodriguez J, Glozak M, Ma Y, Cress W. Bok, Bcl-2-related ovarian killer, is cell cycle-regulated and sensitizes to stress-induced apoptosis. J Biol Chem 2006; 281:22729-35.
    • (2006) J Biol Chem , vol.281 , pp. 22729-22735
    • Rodriguez, J.1    Glozak, M.2    Ma, Y.3    Cress, W.4    Bok5
  • 31
    • 24944474714 scopus 로고    scopus 로고
    • Bim is a direct target of a neuronal E2F-dependent apoptotic pathway
    • Biswas SC, Liu DX, Greene LA. Bim is a direct target of a neuronal E2F-dependent apoptotic pathway. J Neurosci 2005; 25:8349-58.
    • (2005) J Neurosci , vol.25 , pp. 8349-8358
    • Biswas, S.C.1    Liu, D.X.2    Greene, L.A.3
  • 32
    • 1542305653 scopus 로고    scopus 로고
    • Upregulation of Bcl-2 homology 3 (BH3)-only proteins by E2F1 mediates apoptosis
    • Hershko T, Ginsberg D. Upregulation of Bcl-2 homology 3 (BH3)-only proteins by E2F1 mediates apoptosis. J Biol Chem 2004; 279:8627-34.
    • (2004) J Biol Chem , vol.279 , pp. 8627-8634
    • Hershko, T.1    Ginsberg, D.2
  • 34
    • 9744256274 scopus 로고    scopus 로고
    • Transcriptional regulation of AKT activation by E2F
    • Chaussepied M, Ginsberg D. Transcriptional regulation of AKT activation by E2F. Mol Cell 2004; 16:831-7.
    • (2004) Mol Cell , vol.16 , pp. 831-837
    • Chaussepied, M.1    Ginsberg, D.2
  • 35
    • 0036311177 scopus 로고    scopus 로고
    • E2F1 induces phosphorylation of p53 that is coincident with p53 accumulation and apoptosis
    • Rogoff HA, Pickering MT, Debatis ME, Jones S, Kowalik TF. E2F1 induces phosphorylation of p53 that is coincident with p53 accumulation and apoptosis. Mol Cell Biol 2002; 22:5308-18.
    • (2002) Mol Cell Biol , vol.22 , pp. 5308-5318
    • Rogoff, H.A.1    Pickering, M.T.2    Debatis, M.E.3    Jones, S.4    Kowalik, T.F.5
  • 36
  • 37
    • 0028061670 scopus 로고
    • Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis
    • Shan B, Lee W-H. Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis. Mol Cell Biol 1994; 14:8166-73.
    • (1994) Mol Cell Biol , vol.14 , pp. 8166-8173
    • Shan, B.1    Lee, W.-H.2
  • 38
    • 33749592371 scopus 로고    scopus 로고
    • A gradient of epidermal growth factor receptor signaling determines the sensitivity of rbf1 mutant cells to E2F-dependent apoptosis
    • Moon N, Di Stefano L, Dyson N. A gradient of epidermal growth factor receptor signaling determines the sensitivity of rbf1 mutant cells to E2F-dependent apoptosis. Mol Cell Biol 2006; 26:7601-15.
    • (2006) Mol Cell Biol , vol.26 , pp. 7601-7615
    • Moon, N.1    Di Stefano, L.2    Dyson, N.3
  • 40
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
    • Datta SR, Dudek H, Tao X, Masters S, Fu H, Gotoh Y, et al. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 1997; 91:231-41.
    • (1997) Cell , vol.91 , pp. 231-241
    • Datta, S.R.1    Dudek, H.2    Tao, X.3    Masters, S.4    Fu, H.5    Gotoh, Y.6
  • 41
    • 1842333237 scopus 로고    scopus 로고
    • del Peso L, Gonzalez-Garcia M, Page C, Herrera R, Nunez G. Interleukin 3 induced phosphorylation of BAD through the protein kinase Akt. Science 1997; 278:687-9.
    • del Peso L, Gonzalez-Garcia M, Page C, Herrera R, Nunez G. Interleukin 3 induced phosphorylation of BAD through the protein kinase Akt. Science 1997; 278:687-9.
  • 43
    • 0035949588 scopus 로고    scopus 로고
    • A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus
    • Mayo LD, Donner DB. A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus. Proc Natl Acad Sci USA 2001; 98:11598-603.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 11598-11603
    • Mayo, L.D.1    Donner, D.B.2
  • 44
    • 0035736487 scopus 로고    scopus 로고
    • HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation
    • Zhou BP, Liao Y, Xia W, Zou Y, Spohn B, Hung M-C. HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation. Nat Cell Biol 2001; 3:973-82.
    • (2001) Nat Cell Biol , vol.3 , pp. 973-982
    • Zhou, B.P.1    Liao, Y.2    Xia, W.3    Zou, Y.4    Spohn, B.5    Hung, M.-C.6
  • 46
    • 33751384465 scopus 로고    scopus 로고
    • GATHER: A systems approach to interpreting genomic signatures
    • Chang JT, Nevins JR. GATHER: a systems approach to interpreting genomic signatures. Bioinformatics 2006; 22:2926-33.
    • (2006) Bioinformatics , vol.22 , pp. 2926-2933
    • Chang, J.T.1    Nevins, J.R.2
  • 47
    • 20844449238 scopus 로고    scopus 로고
    • AMP activated protein kinase induces a p53-dependent metabolic checkpoint
    • Jones RG, Plas DR, Kubek S, Buzzai M, Mu J, Xu Y, et al. AMP activated protein kinase induces a p53-dependent metabolic checkpoint. Mol Cell 2005; 18:283-92.
    • (2005) Mol Cell , vol.18 , pp. 283-292
    • Jones, R.G.1    Plas, D.R.2    Kubek, S.3    Buzzai, M.4    Mu, J.5    Xu, Y.6
  • 49
    • 0030977267 scopus 로고    scopus 로고
    • Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis
    • Cheng LE, Chan FK, Cado D, Winoto A. Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis. EMBO J 1997; 16:1865-75.
    • (1997) EMBO J , vol.16 , pp. 1865-1875
    • Cheng, L.E.1    Chan, F.K.2    Cado, D.3    Winoto, A.4
  • 50
    • 34250019385 scopus 로고    scopus 로고
    • Abrogation of nuclear receptors Nr4a3 and Nr4a1 leads to development of acute myeloid leukemia
    • Mullican S, Zhang S, Konopleva M, Ruvolo V, Andreeff M, Milbrandt J, et al. Abrogation of nuclear receptors Nr4a3 and Nr4a1 leads to development of acute myeloid leukemia. Nat Med 2007; 13:730-5.
    • (2007) Nat Med , vol.13 , pp. 730-735
    • Mullican, S.1    Zhang, S.2    Konopleva, M.3    Ruvolo, V.4    Andreeff, M.5    Milbrandt, J.6
  • 51
    • 39749099315 scopus 로고    scopus 로고
    • MLLT3 regulates early human erythroid and megakaryocytic cell fate
    • Pina C, May G, Soneji S, Hong D, Enver T. MLLT3 regulates early human erythroid and megakaryocytic cell fate. Cell Stem Cell 2008; 2:264-73.
    • (2008) Cell Stem Cell , vol.2 , pp. 264-273
    • Pina, C.1    May, G.2    Soneji, S.3    Hong, D.4    Enver, T.5
  • 52
    • 0029743304 scopus 로고    scopus 로고
    • A unique human gene that spans over 230 kb in the human chromosome 8p11-12 and codes multiple family proteins sharing RNA-binding motifs
    • Shimamoto A, Kitao S, Ichikawa K, Suzuki N, Yamabe Y, Imamura O, et al. A unique human gene that spans over 230 kb in the human chromosome 8p11-12 and codes multiple family proteins sharing RNA-binding motifs. Proc Natl Acad Sci USA 1996; 93:10913-7.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 10913-10917
    • Shimamoto, A.1    Kitao, S.2    Ichikawa, K.3    Suzuki, N.4    Yamabe, Y.5    Imamura, O.6
  • 53
    • 33644776551 scopus 로고    scopus 로고
    • Jab1 is a specificity factor for E2F1-induced apoptosis
    • Hallstrom TC, Nevins JR. Jab1 is a specificity factor for E2F1-induced apoptosis. Genes Dev 2006; 20:613-23.
    • (2006) Genes Dev , vol.20 , pp. 613-623
    • Hallstrom, T.C.1    Nevins, J.R.2
  • 55
    • 27644583723 scopus 로고    scopus 로고
    • Distinctions in the specificity of E2F function revealed by gene expression signatures
    • Black EP, Hallstrom T, Dressman HK, West M, Nevins JR. Distinctions in the specificity of E2F function revealed by gene expression signatures. Proc Natl Acad Sci USA 2005; 102:15948-53.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 15948-15953
    • Black, E.P.1    Hallstrom, T.2    Dressman, H.K.3    West, M.4    Nevins, J.R.5
  • 56
    • 0038246295 scopus 로고    scopus 로고
    • Identification of the E box factor TFE3 as a functional partner for the E2F3 transcription factor
    • Giangrande PH, Hallstrom TC, Tunyaplin C, Calame K, Nevins JR. Identification of the E box factor TFE3 as a functional partner for the E2F3 transcription factor. Mol Cell Biol 2003; 23:3707-20.
    • (2003) Mol Cell Biol , vol.23 , pp. 3707-3720
    • Giangrande, P.H.1    Hallstrom, T.C.2    Tunyaplin, C.3    Calame, K.4    Nevins, J.R.5
  • 57
    • 0036846197 scopus 로고    scopus 로고
    • Interaction of YY1 with E2Fs, mediated by RYBP, provides a mechanism for specificity of E2F function
    • Schlisio S, Halperin T, Vidal M, Nevins JR. Interaction of YY1 with E2Fs, mediated by RYBP, provides a mechanism for specificity of E2F function. EMBO J 2002; 21:5775-86.
    • (2002) EMBO J , vol.21 , pp. 5775-5786
    • Schlisio, S.1    Halperin, T.2    Vidal, M.3    Nevins, J.R.4
  • 58
    • 31144459985 scopus 로고    scopus 로고
    • Oncogenic pathway signatures in human cancers as a guide to targeted therapies
    • Bild AH, Yao G, Chang JT, Wang Q, Potti A, Chasse D, et al. Oncogenic pathway signatures in human cancers as a guide to targeted therapies. Nature 2006; 439:353-7.
    • (2006) Nature , vol.439 , pp. 353-357
    • Bild, A.H.1    Yao, G.2    Chang, J.T.3    Wang, Q.4    Potti, A.5    Chasse, D.6
  • 59
    • 0034773404 scopus 로고    scopus 로고
    • Role of AMP-activated protein kinase in mechanism of metformin action
    • Zhou G, Myers R, Li Y, Chen Y, Shen X, Fenyk-Melody J, et al. Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest 2001; 108:1167-74.
    • (2001) J Clin Invest , vol.108 , pp. 1167-1174
    • Zhou, G.1    Myers, R.2    Li, Y.3    Chen, Y.4    Shen, X.5    Fenyk-Melody, J.6
  • 60
    • 33645766204 scopus 로고    scopus 로고
    • Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin
    • Bowker SL, Majumdar SR, Veugelers P, Johnson JA. Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin. Diabetes Care 2006; 29:254-8.
    • (2006) Diabetes Care , vol.29 , pp. 254-258
    • Bowker, S.L.1    Majumdar, S.R.2    Veugelers, P.3    Johnson, J.A.4


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