메뉴 건너뛰기




Volumn 1, Issue 3, 2001, Pages 222-231

To cycle or not to cycle: A critical decision in cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CDK2 PROTEIN, HUMAN; CDK2 PROTEIN, MOUSE; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 2; CYCLINE; ENZYME INHIBITOR; PROTEIN SERINE THREONINE KINASE; TUMOR PROTEIN;

EID: 0035754080     PISSN: 1474175X     EISSN: None     Source Type: Journal    
DOI: 10.1038/35106065     Document Type: Article
Times cited : (1248)

References (21)
  • 1
    • 0026693966 scopus 로고
    • Animal cell cycles and their control
    • Norbury, C. & Nurse, P. Animal cell cycles and their control. Annu. Rev. Biochem. 61, 441-470 (1992).
    • (1992) Annu. Rev. Biochem. , vol.61 , pp. 441-470
    • Norbury, C.1    Nurse, P.2
  • 2
    • 0024425887 scopus 로고
    • Checkpoints: Controls that ensure the order of cell cycle events
    • Hartwell, L. & Weinert, T. Checkpoints: controls that ensure the order of cell cycle events. Science 246, 629-634 (1989).
    • (1989) Science , vol.246 , pp. 629-634
    • Hartwell, L.1    Weinert, T.2
  • 3
    • 0031466305 scopus 로고    scopus 로고
    • Cyclin-dependent kinases: Engines, clocks, and microprocessors
    • Morgan, D. O. Cyclin-dependent kinases: engines, clocks, and microprocessors. Annu. Rev. Cell Dev. Biol. 13, 261-291 (1997).
    • (1997) Annu. Rev. Cell Dev. Biol. , vol.13 , pp. 261-291
    • Morgan, D.O.1
  • 4
    • 0034660892 scopus 로고    scopus 로고
    • Cancer cell cycles revisited
    • Sherr, C. J. Cancer cell cycles revisited. Cancer Res. 60, 3689-3695 (2000).
    • (2000) Cancer Res. , vol.60 , pp. 3689-3695
    • Sherr, C.J.1
  • 5
    • 0028181760 scopus 로고
    • 1 kinase activity for cdk6, a novel cyclin D partner
    • 1 kinase activity for cdk6, a novel cyclin D partner. Mol. Cell. Biol. 14, 2077-2086 (1994).
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 2077-2086
    • Meyerson, M.1    Harlow, E.2
  • 6
    • 0033539475 scopus 로고    scopus 로고
    • Oncogenic stimulation recruits cyclin-dependent kinase in the cell cycle start in rat fibroblast
    • Jinno, S. et al. Oncogenic stimulation recruits cyclin-dependent kinase in the cell cycle start in rat fibroblast. Proc. Natl Acad. Sci. USA 96, 13197-13202 (1999).
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 13197-13202
    • Jinno, S.1
  • 7
    • 0032937751 scopus 로고    scopus 로고
    • Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in B-cell hyperplasia
    • Rane, S. G. et al. Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in B-cell hyperplasia. Nature Genet. 22, 44-52 (1999).
    • (1999) Nature Genet. , vol.22 , pp. 44-52
    • Rane, S.G.1
  • 8
    • 0032849353 scopus 로고    scopus 로고
    • Targeted disruption of Cdk4 delays cell cycle entry with enhanced p27Kip1 activity
    • Tsutsui, T. et al. Targeted disruption of Cdk4 delays cell cycle entry with enhanced p27Kip1 activity. Mol. Cell. Biol. 19, 7011-7019 (1999). References 7 and 8 describe the generation of mice that are deficient for Cdk4. Cdk4 seems to be dispensable for the cell cycle in most cell types. Ablation of Cdk4, however, severely affects proliferation of specific cell types, such as pancreatic β-cells, which leads to diabetes.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 7011-7019
    • Tsutsui, T.1
  • 9
    • 0035852699 scopus 로고    scopus 로고
    • A premature-termination mutation in the Mus musculus cyclin-dependent kinase 3 gene
    • Ye, X., Zhu, C. & Harper, W. A premature-termination mutation in the Mus musculus cyclin-dependent kinase 3 gene. Proc. Natl Acad. Sci. USA 13, 1682-1686 (2001).
    • (2001) Proc. Natl Acad. Sci. USA , vol.13 , pp. 1682-1686
    • Ye, X.1    Zhu, C.2    Harper, W.3
  • 10
    • 0029952160 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 7: At the cross-roads of transcription, DNA repair and cell cycle control?
    • Nigg, E. A. Cyclin-dependent kinase 7: at the cross-roads of transcription, DNA repair and cell cycle control? Curr. Opin. Cell Biol. 8, 312-317 (1996).
    • (1996) Curr. Opin. Cell Biol. , vol.8 , pp. 312-317
    • Nigg, E.A.1
  • 11
    • 0033711708 scopus 로고    scopus 로고
    • 1 cyclin-dependent kinases in the mammalian cell cycle
    • 1 cyclin-dependent kinases in the mammalian cell cycle. Curr. Opin. Cell Biol. 12, 676-684 (2000).
    • (2000) Curr. Opin. Cell Biol. , vol.12 , pp. 676-684
    • Ekholm, S.V.1    Reed, S.I.2
  • 12
    • 0001139669 scopus 로고    scopus 로고
    • Ras pathways to cell cycle control and cell transformation
    • Malumbres, M. & Pellicer, A. Ras pathways to cell cycle control and cell transformation. Front. Biosci. 3, D887-D912 (1998).
    • (1998) Front. Biosci. , vol.3
    • Malumbres, M.1    Pellicer, A.2
  • 13
    • 0032533225 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3β regulates cyclin D1 proteolysis and subcellular localization
    • Diehl, J. A., Cheng, M., Roussel, M. F. & Sherr, C. J. Glycogen synthase kinase-3β regulates cyclin D1 proteolysis and subcellular localization. Genes Dev. 12, 3499-3511 (1998).
    • (1998) Genes Dev. , vol.12 , pp. 3499-3511
    • Diehl, J.A.1    Cheng, M.2    Roussel, M.F.3    Sherr, C.J.4
  • 14
    • 0034671768 scopus 로고    scopus 로고
    • Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation
    • Alt, J. R., Cleveland, J. L., Hannink, M. & Diehl, J. A. Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation. Genes Dev. 14, 3102-3114 (2000).
    • (2000) Genes Dev. , vol.14 , pp. 3102-3114
    • Alt, J.R.1    Cleveland, J.L.2    Hannink, M.3    Diehl, J.A.4
  • 15
    • 0028889751 scopus 로고
    • Mice lacking cyclin D1 are small and show defects in eye and mammary gland development
    • Fantl, V., Stamp, G., Andrews, A., Rosewell, I. & Dickson, C. Mice lacking cyclin D1 are small and show defects in eye and mammary gland development. Genes Dev. 9, 2364-2372 (1995).
    • (1995) Genes Dev. , vol.9 , pp. 2364-2372
    • Fantl, V.1    Stamp, G.2    Andrews, A.3    Rosewell, I.4    Dickson, C.5
  • 16
    • 0029111934 scopus 로고
    • Cyclin D1 provides a link between development and oncogenesis in the retina and breast
    • Sicinski, P. et al. Cyclin D1 provides a link between development and oncogenesis in the retina and breast. Cell 82, 621-630 (1995).
    • (1995) Cell , vol.82 , pp. 621-630
    • Sicinski, P.1
  • 17
    • 0033564697 scopus 로고    scopus 로고
    • Cdk inhibitors: Positive and negative regulators of G1-phase progression
    • Sherr, C. J. & Roberts, J. M. Cdk inhibitors: positive and negative regulators of G1-phase progression. Genes Dev. 13, 1501-1512 (1999).
    • (1999) Genes Dev. , vol.13 , pp. 1501-1512
    • Sherr, C.J.1    Roberts, J.M.2
  • 18
    • 0035095973 scopus 로고    scopus 로고
    • Regulation of the retinoblastoma tumor suppressor protein by cyclin/CDKs
    • Adams, P. D. Regulation of the retinoblastoma tumor suppressor protein by cyclin/CDKs. Biochim. Biophys. Acta 1471, 123-133 (2001).
    • (2001) Biochim. Biophys. Acta , vol.1471 , pp. 123-133
    • Adams, P.D.1
  • 19
    • 0034306996 scopus 로고    scopus 로고
    • The pRb/E2F pathway: Expanding roles and emerging paradigms
    • Harbour, J. W. & Dean, D. C. The pRb/E2F pathway: expanding roles and emerging paradigms. Genes Dev. 14, 2393-2409 (2000).
    • (2000) Genes Dev. , vol.14 , pp. 2393-2409
    • Harbour, J.W.1    Dean, D.C.2
  • 20
    • 0034964014 scopus 로고    scopus 로고
    • Retinoblastoma protein partners
    • Morris, E. J. & Dyson, N. J. Retinoblastoma protein partners. Adv. Cancer Res. 82, 1-54 (2001).
    • (2001) Adv. Cancer Res. , vol.82 , pp. 1-54
    • Morris, E.J.1    Dyson, N.J.2
  • 21
    • 0031951182 scopus 로고    scopus 로고
    • Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-CDK complexes
    • Lundberg, A. S. & Weinberg, R. A. Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-CDK complexes. Mol. Cell. Biol. 18, 753-761 (1998).
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 753-761
    • Lundberg, A.S.1    Weinberg, R.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.