-
1
-
-
0036884829
-
The retinoblastoma tumour suppressor in development and cancer
-
Classon, M. & Harlow E. The retinoblastoma tumour suppressor in development and cancer. Nature Rev. Cancer 2, 910-917 (2002).
-
(2002)
Nature Rev. Cancer
, vol.2
, pp. 910-917
-
-
Classon, M.1
Harlow, E.2
-
2
-
-
0035020826
-
Requirement for p27(KIP1) in retinoblastoma protein-mediated senescence
-
Alexander, K. & Hinds P. W. Requirement for p27(KIP1) in retinoblastoma protein-mediated senescence. Mol. Cell. Biol. 21, 3616-3631 (2001).
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 3616-3631
-
-
Alexander, K.1
Hinds, P.W.2
-
3
-
-
4944252223
-
An Rb-Skp2-p27 pathway mediates acute cell cycle inhibition by Rb and is retained in a partial-penetrance Rb mutant
-
Ji, P. et al. An Rb-Skp2-p27 pathway mediates acute cell cycle inhibition by Rb and is retained in a partial-penetrance Rb mutant. Mol. Cell. 16, 47-58 (2004).
-
(2004)
Mol. Cell.
, vol.16
, pp. 47-58
-
-
Ji, P.1
-
4
-
-
0033174155
-
Kip1 meets SKP2: New links in cell-cycle control
-
Amati, B. & Vlach J. Kip1 meets SKP2: New links in cell-cycle control. Nature Cell Biol. 1, E91-E93 (1999).
-
(1999)
Nature Cell Biol.
, vol.1
-
-
Amati, B.1
Vlach, J.2
-
5
-
-
0029033861
-
The retinoblastoma protein and cell cycle control
-
Weinberg, R. A. The retinoblastoma protein and cell cycle control. Cell 81, 323-330 (1995).
-
(1995)
Cell
, vol.81
, pp. 323-330
-
-
Weinberg, R.A.1
-
6
-
-
10344237022
-
Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma
-
Thomas, D. M. et al. Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma. J. Cell. Biol. 167, 925-934 (2004).
-
(2004)
J. Cell. Biol.
, vol.167
, pp. 925-934
-
-
Thomas, D.M.1
-
7
-
-
0037325853
-
Deregulated degradation of the cdk inhibitor p27 and malignant transformation
-
Bloom, J. & Pagano M. Deregulated degradation of the cdk inhibitor p27 and malignant transformation. Semin. Cancer Biol. 13, 41-47 (2003).
-
(2003)
Semin. Cancer Biol.
, vol.13
, pp. 41-47
-
-
Bloom, J.1
Pagano, M.2
-
8
-
-
13244283007
-
The anaphase-promoting complex: A key factor in the regulation of cell cycle
-
Castro, A. et al. The anaphase-promoting complex: A key factor in the regulation of cell cycle. Oncogene 24, 314-325 (2005).
-
(2005)
Oncogene
, vol.24
, pp. 314-325
-
-
Castro, A.1
-
9
-
-
0037083918
-
fzr-1 and lin-35/Rb function redundantly to control cell proliferation in C. elegans as revealed by a nonbiased synthetic screen
-
Fay, D. S., Keenan S. & Han M. fzr-1 and lin-35/Rb function redundantly to control cell proliferation in C. elegans as revealed by a nonbiased synthetic screen. Genes Dev 16, 503-517 (2002).
-
(2002)
Genes Dev
, vol.16
, pp. 503-517
-
-
Fay, D.S.1
Keenan, S.2
Han, M.3
-
10
-
-
0034095216
-
Mutagenesis of the pRB pocket reveals that cell cycle arrest functions are separable from binding to viral oncoproteins
-
Dick, F. A., Sailhamer E. & Dyson N. J. Mutagenesis of the pRB pocket reveals that cell cycle arrest functions are separable from binding to viral oncoproteins. Mol. Cell. Biol. 20, 3715-3727 (2000).
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 3715-3727
-
-
Dick, F.A.1
Sailhamer, E.2
Dyson, N.J.3
-
11
-
-
0036100267
-
Three regions of the pRB pocket domain affect its inactivation by human papillomavirus E7 proteins
-
Dick, F. A. & Dyson N. J. Three regions of the pRB pocket domain affect its inactivation by human papillomavirus E7 proteins. J. Virol. 76, 6224-6234 (2002).
-
(2002)
J. Virol.
, vol.76
, pp. 6224-6234
-
-
Dick, F.A.1
Dyson, N.J.2
-
12
-
-
33646250688
-
The retinoblastoma protein regulates pericentric heterochromatin
-
Isaac, C. E. et al. The retinoblastoma protein regulates pericentric heterochromatin. Mol. Cell. Biol. 26, 3659-3671 (2006).
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 3659-3671
-
-
Isaac, C.E.1
-
13
-
-
19444378969
-
The WD40 propeller domain of Cdh1 functions as a destruction box receptor for APC/C substrates
-
Kraft, C. et al. The WD40 propeller domain of Cdh1 functions as a destruction box receptor for APC/C substrates. Mol. Cell. 18, 543-553 (2005).
-
(2005)
Mol. Cell.
, vol.18
, pp. 543-553
-
-
Kraft, C.1
-
14
-
-
0033796454
-
Nonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosis
-
Sorensen, C. S. et al. Nonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosis. Mol. Cell. Biol. 20, 7613-7623 (2000).
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 7613-7623
-
-
Sorensen, C.S.1
-
15
-
-
1642399624
-
Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex
-
Wei, W. et al. Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex. Nature 428, 194-198 (2004).
-
(2004)
Nature
, vol.428
, pp. 194-198
-
-
Wei, W.1
-
16
-
-
1642378661
-
Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase
-
Bashir, T. et al. Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase. Nature. 428, 190-193 (2004).
-
(2004)
Nature
, vol.428
, pp. 190-193
-
-
Bashir, T.1
-
17
-
-
27644582893
-
Probing tumor phenotypes using stable and regulated synthetic microRNA precursors
-
Dickins, R. A. et al. Probing tumor phenotypes using stable and regulated synthetic microRNA precursors. Nature Genet. 37, 1289-1295 (2005).
-
(2005)
Nature Genet.
, vol.37
, pp. 1289-1295
-
-
Dickins, R.A.1
-
18
-
-
30344466977
-
The processivity of multiubiquitination by the APC determines the order of substrate degradation
-
Rape, M., Reddy S. K. & Kirschner M. W. The processivity of multiubiquitination by the APC determines the order of substrate degradation. Cell 12, 89-103 (2006).
-
(2006)
Cell
, vol.12
, pp. 89-103
-
-
Rape, M.1
Reddy, S.K.2
Kirschner, M.W.3
-
19
-
-
28444451188
-
The APC/C and CBP/p300 cooperate to regulate transcription and cell-cycle progression
-
Turnell, A. S. et al. The APC/C and CBP/p300 cooperate to regulate transcription and cell-cycle progression. Nature 438, 690-695 (2005).
-
(2005)
Nature
, vol.438
, pp. 690-695
-
-
Turnell, A.S.1
-
20
-
-
0035498980
-
Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN
-
Stroschein, S. L. et al. Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN. Genes Dev. 15, 2822-2836 (2001).
-
(2001)
Genes Dev.
, vol.15
, pp. 2822-2836
-
-
Stroschein, S.L.1
-
21
-
-
0035930333
-
The anaphase-promoting complex mediates TGF-β signaling by targeting SnoN for destruction
-
Wan, Y., Liu X. & Kirschner M. W. The anaphase-promoting complex mediates TGF-β signaling by targeting SnoN for destruction. Mol. Cell. 8, 1027-1039 (2001).
-
(2001)
Mol. Cell.
, vol.8
, pp. 1027-1039
-
-
Wan, Y.1
Liu, X.2
Kirschner, M.W.3
-
22
-
-
20444429760
-
Binding of pRB to the PHD protein RBP2 promotes cellular differentiation
-
Benevolenskaya, E. V. et al. Binding of pRB to the PHD protein RBP2 promotes cellular differentiation. Mol. Cell. 18, 623-635 (2005).
-
(2005)
Mol. Cell.
, vol.18
, pp. 623-635
-
-
Benevolenskaya, E.V.1
-
23
-
-
0034458872
-
Cells degrade a novel inhibitor of differentiation with E1A-like properties upon exiting the cell cycle
-
Miyake, S. et al. Cells degrade a novel inhibitor of differentiation with E1A-like properties upon exiting the cell cycle. Mol. Cell. Biol. 20, 8889-8902 (2000).
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 8889-8902
-
-
Miyake, S.1
-
24
-
-
33747087307
-
Degradation of Id2 by the anaphase-promoting complex couples cell cycle exit and axonal growth
-
Lasorella, A. et al. Degradation of Id2 by the anaphase-promoting complex couples cell cycle exit and axonal growth. Nature 442, 471-474 (2006).
-
(2006)
Nature
, vol.442
, pp. 471-474
-
-
Lasorella, A.1
-
25
-
-
19344375385
-
Interwoven ubiquitination oscillators and control of cell cycle transitions
-
Ang, X. L. & Harper J. W. Interwoven ubiquitination oscillators and control of cell cycle transitions. Sci STKE e31 (2004).
-
(2004)
Sci STKE
-
-
Ang, X.L.1
Harper, J.W.2
-
26
-
-
8844276742
-
Independent regulation of synaptic size and activity by the anaphase-promoting complex
-
van Roessel, P. et al. Independent regulation of synaptic size and activity by the anaphase-promoting complex. Cell 119, 707-718 (2004).
-
(2004)
Cell
, vol.119
, pp. 707-718
-
-
van Roessel, P.1
-
27
-
-
0141927097
-
pRB contains an E2F1-specific binding domain that allows E2F1-induced apoptosis to be regulated separately from other E2F activities
-
Dick, F. A. & Dyson N. J. pRB contains an E2F1-specific binding domain that allows E2F1-induced apoptosis to be regulated separately from other E2F activities. Mol. Cell. 12, 639-649 (2003).
-
(2003)
Mol. Cell.
, vol.12
, pp. 639-649
-
-
Dick, F.A.1
Dyson, N.J.2
-
28
-
-
0021100690
-
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
-
Dignam, J. D., Lebovitz R. M. & Roeder R. G. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11, 1475-1489 (1983).
-
(1983)
Nucleic Acids Res.
, vol.11
, pp. 1475-1489
-
-
Dignam, J.D.1
Lebovitz, R.M.2
Roeder, R.G.3
-
29
-
-
0041633899
-
Cell cycle-dependent regulation of the Skp2 promoter by GA-binding protein
-
Imaki, H. et al. Cell cycle-dependent regulation of the Skp2 promoter by GA-binding protein. Cancer Res. 63, 4607-4613 (2003).
-
(2003)
Cancer Res.
, vol.63
, pp. 4607-4613
-
-
Imaki, H.1
-
30
-
-
0034675922
-
The F-box protein Skp2 is a ubiquitylation target of a Cul1-based core ubiquitin ligase complex: Evidence for a role of Cul1 in the suppression of Skp2 expression in quiescent fibroblasts
-
Wirbelauer, C. et al. The F-box protein Skp2 is a ubiquitylation target of a Cul1-based core ubiquitin ligase complex: Evidence for a role of Cul1 in the suppression of Skp2 expression in quiescent fibroblasts. EMBO J. 19, 5362-5375 (2000).
-
(2000)
EMBO J.
, vol.19
, pp. 5362-5375
-
-
Wirbelauer, C.1
-
31
-
-
0028980273
-
p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase
-
Zhang, H. et al. p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase. Cell 82, 915-925 (1995).
-
(1995)
Cell
, vol.82
, pp. 915-925
-
-
Zhang, H.1
-
32
-
-
0242495787
-
Identification of target genes of the p16INK4A-pRB-E2F pathway
-
Vernell, R., Helin K. & Muller H. Identification of target genes of the p16INK4A-pRB-E2F pathway. J. Biol. Chem. 278, 46124-46137 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 46124-46137
-
-
Vernell, R.1
Helin, K.2
Muller, H.3
|