-
1
-
-
37749044421
-
Synthetic agonists of Toll-like receptors 7, 8 and 9
-
1:CAS:528:DC%2BD2sXhtlGmtL3N 10.1042/BST0351461 18031246
-
S Agrawal ER Kandimalla 2007 Synthetic agonists of Toll-like receptors 7, 8 and 9 Biochem Soc Trans 35 1461 1467 1:CAS:528:DC%2BD2sXhtlGmtL3N 10.1042/BST0351461 18031246
-
(2007)
Biochem Soc Trans
, vol.35
, pp. 1461-1467
-
-
Agrawal, S.1
Kandimalla, E.R.2
-
2
-
-
0035211130
-
Human MD-2 confers on mouse Toll-like receptor 4 species-specific lipopolysaccharide recognition
-
1:CAS:528:DC%2BD3MXptVKmt7Y%3D 10.1093/intimm/13.12.1595 11717200
-
S Akashi Y Nagai H Ogata M Oikawa K Fukase S Kusumoto K Kawasaki M Nishijima S Hayashi M Kimoto K Miyake 2001 Human MD-2 confers on mouse Toll-like receptor 4 species-specific lipopolysaccharide recognition Int Immunol 13 1595 1599 1:CAS:528:DC%2BD3MXptVKmt7Y%3D 10.1093/intimm/13.12.1595 11717200
-
(2001)
Int Immunol
, vol.13
, pp. 1595-1599
-
-
Akashi, S.1
Nagai, Y.2
Ogata, H.3
Oikawa, M.4
Fukase, K.5
Kusumoto, S.6
Kawasaki, K.7
Nishijima, M.8
Hayashi, S.9
Kimoto, M.10
Miyake, K.11
-
3
-
-
0036344106
-
Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice
-
1:CAS:528:DC%2BD38Xls12msLg%3D 12091878
-
L Alexopoulou V Thomas M Schnare Y Lobet J Anguita RT Schoen R Medzhitov E Fikrig RA Flavell 2002 Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice Nat Med 8 878 884 1:CAS:528:DC%2BD38Xls12msLg%3D 12091878
-
(2002)
Nat Med
, vol.8
, pp. 878-884
-
-
Alexopoulou, L.1
Thomas, V.2
Schnare, M.3
Lobet, Y.4
Anguita, J.5
Schoen, R.T.6
Medzhitov, R.7
Fikrig, E.8
Flavell, R.A.9
-
4
-
-
78650303870
-
Evaluation of mucosal bacteria and histopathology, clinical disease activity and expression of Toll-like receptors in German shepherd dogs with chronic enteropathies
-
doi: 10.1016/j.vetmic.2010.05.025
-
Allenspach K, House A, Smith K, McNeill FM, Hendricks A, Elson-Riggins J, Riddle A, Steiner JM, Werling D, Garden OA, Catchpole B, Suchodolski JS (2010) Evaluation of mucosal bacteria and histopathology, clinical disease activity and expression of Toll-like receptors in German shepherd dogs with chronic enteropathies. Vet Microbiol. doi: 10.1016/j.vetmic.2010.05.025
-
(2010)
Vet Microbiol
-
-
Allenspach, K.1
House, A.2
Smith, K.3
McNeill, F.M.4
Hendricks, A.5
Elson-Riggins, J.6
Riddle, A.7
Steiner, J.M.8
Werling, D.9
Garden, O.A.10
Catchpole, B.11
Suchodolski, J.S.12
-
5
-
-
34248185036
-
Toll-like receptor 7 and MyD88 knockdown by lentivirus-mediated RNA interference to porcine dendritic cell subsets
-
DOI 10.1038/sj.gt.3302930, PII 3302930
-
MP Alves V Neuhaus L Guzylack-Piriou N Ruggli KC McCullough A Summerfield 2007 Toll-like receptor 7 and MyD88 knockdown by lentivirus-mediated RNA interference to porcine dendritic cell subsets Gene Ther 14 836 844 1:CAS:528:DC%2BD2sXkvVOju7k%3D 10.1038/sj.gt.3302930 17330086 (Pubitemid 46706062)
-
(2007)
Gene Therapy
, vol.14
, Issue.10
, pp. 836-844
-
-
Alves, M.P.1
Neuhaus, V.2
Guzylack-Piriou, L.3
Ruggli, N.4
McCullough, K.C.5
Summerfield, A.6
-
6
-
-
22944433876
-
The success and failure of BCG - Implications for a novel tuberculosis vaccine
-
DOI 10.1038/nrmicro1211
-
P Andersen TM Doherty 2005 The success and failure of BCG - implications for a novel tuberculosis vaccine Nat Rev Microbiol 3 656 662 1:CAS:528:DC%2BD2MXmvVGhur0%3D 10.1038/nrmicro1211 16012514 (Pubitemid 41052152)
-
(2005)
Nature Reviews Microbiology
, vol.3
, Issue.8
, pp. 656-662
-
-
Andersen, P.1
Doherty, T.M.2
-
8
-
-
0037380645
-
Endothelium-derived Toll-like receptor-4 is the key molecule in LPS-induced neutrophil sequestration into lungs
-
1:CAS:528:DC%2BD3sXislOgtr4%3D 12671050
-
G Andonegui CS Bonder F Green SC Mullaly L Zbytnuik E Raharjo P Kubes 2003 Endothelium-derived Toll-like receptor-4 is the key molecule in LPS-induced neutrophil sequestration into lungs J Clin Invest 111 1011 1020 1:CAS:528:DC%2BD3sXislOgtr4%3D 12671050
-
(2003)
J Clin Invest
, vol.111
, pp. 1011-1020
-
-
Andonegui, G.1
Bonder, C.S.2
Green, F.3
Mullaly, S.C.4
Zbytnuik, L.5
Raharjo, E.6
Kubes, P.7
-
9
-
-
65449161773
-
A novel regulatory B-cell population in sheep Peyer's patches spontaneously secretes IL-10 and downregulates TLR9-induced IFNalpha responses
-
1:CAS:528:DC%2BD1MXksFGhtrc%3D 10.1038/mi.2009.6 19262501
-
JS Booth PJ Griebel LA Babiuk GK Mutwiri 2009 A novel regulatory B-cell population in sheep Peyer's patches spontaneously secretes IL-10 and downregulates TLR9-induced IFNalpha responses Mucosal Immunol 2 265 275 1:CAS:528:DC%2BD1MXksFGhtrc%3D 10.1038/mi.2009.6 19262501
-
(2009)
Mucosal Immunol
, vol.2
, pp. 265-275
-
-
Booth, J.S.1
Griebel, P.J.2
Babiuk, L.A.3
Mutwiri, G.K.4
-
10
-
-
77953398245
-
Co-stimulation with TLR7/8 and TLR9 agonists induce down-regulation of innate immune responses in sheep blood mononuclear and B cells
-
1:CAS:528:DC%2BC3cXitVOjs7s%3D 10.1016/j.dci.2009.12.018 20051250
-
JS Booth JJ Buza A Potter LA Babiuk GK Mutwiri 2010 Co-stimulation with TLR7/8 and TLR9 agonists induce down-regulation of innate immune responses in sheep blood mononuclear and B cells Dev Comp Immunol 34 572 578 1:CAS:528:DC%2BC3cXitVOjs7s%3D 10.1016/j.dci.2009.12.018 20051250
-
(2010)
Dev Comp Immunol
, vol.34
, pp. 572-578
-
-
Booth, J.S.1
Buza, J.J.2
Potter, A.3
Babiuk, L.A.4
Mutwiri, G.K.5
-
11
-
-
33646880189
-
The TLR4 agonist, monophosphoryl lipid A, attenuates the cytokine storm associated with respiratory syncytial virus vaccine-enhanced disease
-
DOI 10.1016/j.vaccine.2006.03.064, PII S0264410X06003483
-
MS Boukhvalova GA Prince L Soroush DC Harrigan SN Vogel JC Blanco 2006 The TLR4 agonist, monophosphoryl lipid A, attenuates the cytokine storm associated with respiratory syncytial virus vaccine-enhanced disease Vaccine 24 5027 5035 1:CAS:528:DC%2BD28XltF2rtro%3D 10.1016/j.vaccine.2006.03.064 16675071 (Pubitemid 43782692)
-
(2006)
Vaccine
, vol.24
, Issue.23
, pp. 5027-5035
-
-
Boukhvalova, M.S.1
Prince, G.A.2
Soroush, L.3
Harrigan, D.C.4
Vogel, S.N.5
Blanco, J.C.G.6
-
12
-
-
0036063276
-
Stimulation of B lymphocytes, macrophages, and dendritic cells by protozoan DNA
-
DOI 10.1016/S1286-4579(02)01623-4, PII S1286457902016234
-
WC Brown RS Corral 2002 Stimulation of B lymphocytes, macrophages, and dendritic cells by protozoan DNA Microbes Infect 4 969 974 1:CAS:528: DC%2BD38XltFahu70%3D 10.1016/S1286-4579(02)01623-4 12106790 (Pubitemid 34775239)
-
(2002)
Microbes and Infection
, vol.4
, Issue.9
, pp. 969-974
-
-
Brown, W.C.1
Corral, R.S.2
-
13
-
-
0032716413
-
Modulation of host immune responses by protozoal DNA
-
1:CAS:528:DyaK1MXnsl2ltL8%3D 10.1016/S0165-2427(99)00120-8 10614497
-
WC Brown CE Suarez LK Shoda DM Estes 1999 Modulation of host immune responses by protozoal DNA Vet Immunol Immunopathol 72 87 94 1:CAS:528:DyaK1MXnsl2ltL8%3D 10.1016/S0165-2427(99)00120-8 10614497
-
(1999)
Vet Immunol Immunopathol
, vol.72
, pp. 87-94
-
-
Brown, W.C.1
Suarez, C.E.2
Shoda, L.K.3
Estes, D.M.4
-
15
-
-
68749108013
-
Chicken TLR21 acts as a functional homologue to mammalian TLR9 in the recognition of CpG oligodeoxynucleotides
-
1:CAS:528:DC%2BD1MXhtVaqsrvM 10.1016/j.molimm.2009.06.002 19573927
-
R Brownlie J Zhu B Allan GK Mutwiri LA Babiuk A Potter P Griebel 2009 Chicken TLR21 acts as a functional homologue to mammalian TLR9 in the recognition of CpG oligodeoxynucleotides Mol Immunol 46 3163 3170 1:CAS:528:DC%2BD1MXhtVaqsrvM 10.1016/j.molimm.2009.06.002 19573927
-
(2009)
Mol Immunol
, vol.46
, pp. 3163-3170
-
-
Brownlie, R.1
Zhu, J.2
Allan, B.3
Mutwiri, G.K.4
Babiuk, L.A.5
Potter, A.6
Griebel, P.7
-
16
-
-
33947274240
-
The cellular Toll-like receptor 4 antagonist E5531 can act as an agonist in horse whole blood
-
DOI 10.1016/j.vetimm.2007.01.013, PII S0165242707000396
-
CE Bryant A Ouellette K Lohmann M Vandenplas JN Moore DJ Maskell BA Farnfield 2007 The cellular Toll-like receptor 4 antagonist E5531 can act as an agonist in horse whole blood Vet Immunol Immunopathol 116 182 189 1:CAS:528:DC%2BD2sXjsVenu7c%3D 10.1016/j.vetimm.2007.01.013 17320193 (Pubitemid 46427902)
-
(2007)
Veterinary Immunology and Immunopathology
, vol.116
, Issue.3-4
, pp. 182-189
-
-
Bryant, C.E.1
Ouellette, A.2
Lohmann, K.3
Vandenplas, M.4
Moore, J.N.5
Maskell, D.J.6
Farnfield, B.A.7
-
17
-
-
12344306187
-
Toll-like receptor 6-independent signaling by diacylated lipopeptides
-
DOI 10.1002/eji.200424955
-
U Buwitt-Beckmann H Heine KH Wiesmuller G Jung R Brock S Akira AJ Ulmer 2005 Toll-like receptor 6-independent signaling by diacylated lipopeptides Eur J Immunol 35 282 289 1:CAS:528:DC%2BD2MXnvFeitw%3D%3D 10.1002/eji.200424955 15580661 (Pubitemid 40123875)
-
(2005)
European Journal of Immunology
, vol.35
, Issue.1
, pp. 282-289
-
-
Buwitt-Beckmann, U.1
Heine, H.2
Wiesmuller, K.-H.3
Jung, G.4
Brock, R.5
Akira, S.6
Ulmer, A.J.7
-
18
-
-
29144490013
-
Lipopeptide structure determines TLR2 dependent cell activation level
-
DOI 10.1111/j.1742-4658.2005.05029.x
-
U Buwitt-Beckmann H Heine KH Wiesmuller G Jung R Brock AJ Ulmer 2005 Lipopeptide structure determines TLR2 dependent cell activation level FEBS J 272 6354 6364 1:CAS:528:DC%2BD28XhsVClsw%3D%3D 10.1111/j.1742-4658.2005.05029.x 16336272 (Pubitemid 41815623)
-
(2005)
FEBS Journal
, vol.272
, Issue.24
, pp. 6354-6364
-
-
Buwitt-Beckmann, U.1
Heine, H.2
Wiesmuller, K.-H.3
Jung, G.4
Brock, R.5
Ulmer, A.J.6
-
19
-
-
33646933064
-
TLR1- and TLR6-independent recognition of bacterial lipopeptides
-
DOI 10.1074/jbc.M512525200
-
U Buwitt-Beckmann H Heine KH Wiesmuller G Jung R Brock S Akira AJ Ulmer 2006 TLR1- and TLR6-independent recognition of bacterial lipopeptides J Biol Chem 281 9049 9057 1:CAS:528:DC%2BD28XjtVSktL0%3D 10.1074/jbc.M512525200 16455646 (Pubitemid 43864617)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.14
, pp. 9049-9057
-
-
Buwitt-Beckmann, U.1
Heine, H.2
Wiesmuller, K.-H.3
Jung, G.4
Brock, R.5
Akira, S.6
Ulmer, A.J.7
-
20
-
-
56349146351
-
CD14+ cells are required for IL-12 response in bovine blood mononuclear cells activated with Toll-like receptor (TLR) 7 and TLR8 ligands
-
1:CAS:528:DC%2BD1cXhsVWmtbfN 10.1016/j.vetimm.2008.08.001 18789542
-
J Buza P Benjamin J Zhu HL Wilson G Lipford AM Krieg LA Babiuk GK Mutwiri 2008 CD14+ cells are required for IL-12 response in bovine blood mononuclear cells activated with Toll-like receptor (TLR) 7 and TLR8 ligands Vet Immunol Immunopathol 126 273 282 1:CAS:528:DC%2BD1cXhsVWmtbfN 10.1016/j.vetimm.2008.08. 001 18789542
-
(2008)
Vet Immunol Immunopathol
, vol.126
, pp. 273-282
-
-
Buza, J.1
Benjamin, P.2
Zhu, J.3
Wilson, H.L.4
Lipford, G.5
Krieg, A.M.6
Babiuk, L.A.7
Mutwiri, G.K.8
-
21
-
-
78149432061
-
Improved cellular and humoral immune responses in vivo following targeting of HIV Gag to dendritic cells within human anti-human DEC205 monoclonal antibody
-
Cheong C, Choi JH, Vitale L, He LZ, Trumpfheller C, Bozzacco L, Do Y, Nchinda G, Park SH, Dandamudi DB, Shrestha E, Pack M, Lee HW, Keler T, Steinman RM, Park CG (2010) Improved cellular and humoral immune responses in vivo following targeting of HIV Gag to dendritic cells within human anti-human DEC205 monoclonal antibody. Blood (in press)
-
(2010)
Blood
-
-
Cheong, C.1
Choi, J.H.2
Vitale, L.3
He, L.Z.4
Trumpfheller, C.5
Bozzacco, L.6
Do, Y.7
Nchinda, G.8
Park, S.H.9
Dandamudi, D.B.10
Shrestha, E.11
Pack, M.12
Lee, H.W.13
Keler, T.14
Steinman, R.M.15
Park, C.G.16
-
22
-
-
0028941067
-
E5531, a pure endotoxin antagonist of high potency
-
1:CAS:528:DyaK2MXkvV2ks7k%3D 10.1126/science.7701344 7701344
-
WJ Christ O Asano AL Robidoux M Perez Y Wang GR Dubuc WE Gavin LD Hawkins PD McGuinness MA Mullarkey, et al. 1995 E5531, a pure endotoxin antagonist of high potency Science 268 80 83 1:CAS:528:DyaK2MXkvV2ks7k%3D 10.1126/science. 7701344 7701344
-
(1995)
Science
, vol.268
, pp. 80-83
-
-
Christ, W.J.1
Asano, O.2
Robidoux, A.L.3
Perez, M.4
Wang, Y.5
Dubuc, G.R.6
Gavin, W.E.7
Hawkins, L.D.8
McGuinness, P.D.9
Mullarkey, M.A.10
-
23
-
-
55249084240
-
Toll-like receptor 3 has a protective role against West Nile virus infection
-
DOI 10.1128/JVI.00935-08
-
S Daffis MA Samuel MS Suthar M Gale Jr MS Diamond 2008 Toll-like receptor 3 has a protective role against West Nile virus infection J Virol 82 10349 10358 1:CAS:528:DC%2BD1cXhtlWitbjJ 10.1128/JVI.00935-08 18715906 (Pubitemid 352691152)
-
(2008)
Journal of Virology
, vol.82
, Issue.21
, pp. 10349-10358
-
-
Daffis, S.1
Samuel, M.A.2
Suthar, M.S.3
Gale Jr., M.4
Diamond, M.S.5
-
24
-
-
68249093830
-
CpG oligodeoxynucleotides activate innate immune response that suppresses infectious bronchitis virus replication in chicken embryos
-
10.1637/8560-121808-Reg.1 19630234
-
A Dar A Potter S Tikoo V Gerdts K Lai LA Babiuk G Mutwiri 2009 CpG oligodeoxynucleotides activate innate immune response that suppresses infectious bronchitis virus replication in chicken embryos Avian Dis 53 261 267 10.1637/8560-121808-Reg.1 19630234
-
(2009)
Avian Dis
, vol.53
, pp. 261-267
-
-
Dar, A.1
Potter, A.2
Tikoo, S.3
Gerdts, V.4
Lai, K.5
Babiuk, L.A.6
Mutwiri, G.7
-
25
-
-
76849090972
-
All three classes of CpG ODNs up-regulate IP-10 gene in pigs
-
1:CAS:528:DC%2BC3cXisFartL4%3D 10.1016/j.rvsc.2009.10.003 19896155
-
A Dar A Nichani K Lai A Potter V Gerdts LA Babiuk G Mutwiri 2010 All three classes of CpG ODNs up-regulate IP-10 gene in pigs Res Vet Sci 88 242 250 1:CAS:528:DC%2BC3cXisFartL4%3D 10.1016/j.rvsc.2009.10.003 19896155
-
(2010)
Res Vet Sci
, vol.88
, pp. 242-250
-
-
Dar, A.1
Nichani, A.2
Lai, K.3
Potter, A.4
Gerdts, V.5
Babiuk, L.A.6
Mutwiri, G.7
-
26
-
-
43349087755
-
Heterodimerization of TLR2 with TLR1 or TLR6 expands the ligand spectrum but does not lead to differential signaling
-
DOI 10.1189/jlb.0807586
-
K Farhat S Riekenberg H Heine J Debarry R Lang J Mages U Buwitt-Beckmann K Roschmann G Jung KH Wiesmuller AJ Ulmer 2008 Heterodimerization of TLR2 with TLR1 or TLR6 expands the ligand spectrum but does not lead to differential signaling J Leukoc Biol 83 692 701 1:CAS:528:DC%2BD1cXjtVaqtLY%3D 10.1189/jlb.0807586 18056480 (Pubitemid 351966879)
-
(2008)
Journal of Leukocyte Biology
, vol.83
, Issue.3
, pp. 692-701
-
-
Farhat, K.1
Riekenberg, S.2
Heine, H.3
Debarry, J.4
Lang, R.5
Mages, J.6
Buwitt-Beckmann, U.7
Roschmann, K.8
Jung, G.9
Wiesmuller, K.-H.10
Ulmer, A.J.11
-
27
-
-
44649137559
-
Identification of RNA sequence motifs stimulating sequence-specific TLR8-dependent immune responses
-
1:CAS:528:DC%2BD1cXisl2jsro%3D 18322178
-
A Forsbach JG Nemorin C Montino C Muller U Samulowitz AP Vicari M Jurk GK Mutwiri AM Krieg GB Lipford J Vollmer 2008 Identification of RNA sequence motifs stimulating sequence-specific TLR8-dependent immune responses J Immunol 180 3729 3738 1:CAS:528:DC%2BD1cXisl2jsro%3D 18322178
-
(2008)
J Immunol
, vol.180
, pp. 3729-3738
-
-
Forsbach, A.1
Nemorin, J.G.2
Montino, C.3
Muller, C.4
Samulowitz, U.5
Vicari, A.P.6
Jurk, M.7
Mutwiri, G.K.8
Krieg, A.M.9
Lipford, G.B.10
Vollmer, J.11
-
28
-
-
77956630701
-
Synthetic and natural TLR4 agonists as safe and effective vaccine adjuvants
-
10.1007/978-90-481-9078-2-14 20593273
-
CB Fox M Friede SG Reed GC Ireton 2010 Synthetic and natural TLR4 agonists as safe and effective vaccine adjuvants Subcell Biochem 53 303 321 10.1007/978-90-481-9078-2-14 20593273
-
(2010)
Subcell Biochem
, vol.53
, pp. 303-321
-
-
Fox, C.B.1
Friede, M.2
Reed, S.G.3
Ireton, G.C.4
-
29
-
-
32044471303
-
Evidence for dissociation of TLR mRNA expression and TLR agonist-mediated functions in bovine macrophages
-
DOI 10.1016/j.vetimm.2005.09.002, PII S0165242705002849
-
M Franchini M Schweizer P Matzener I Magkouras KS Sauter J Mirkovitch E Peterhans TW Jungi 2006 Evidence for dissociation of TLR mRNA expression and TLR agonist-mediated functions in bovine macrophages Vet Immunol Immunopathol 110 37 49 1:CAS:528:DC%2BD28XhtlCktrc%3D 10.1016/j.vetimm.2005.09.002 16216336 (Pubitemid 43201961)
-
(2006)
Veterinary Immunology and Immunopathology
, vol.110
, Issue.1-2
, pp. 37-49
-
-
Franchini, M.1
Schweizer, M.2
Matzener, P.3
Magkouras, I.4
Sauter, K.-S.5
Mirkovitch, J.6
Peterhans, E.7
Jungi, T.W.8
-
30
-
-
0038558249
-
Collaborative induction of inflammatory responses by dectin-1 and toll-like receptor 2
-
DOI 10.1084/jem.20021787
-
BN Gantner RM Simmons SJ Canavera S Akira DM Underhill 2003 Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2 J Exp Med 197 1107 1117 1:CAS:528:DC%2BD3sXjs1ygs7g%3D 10.1084/jem.20021787 12719479 (Pubitemid 36570066)
-
(2003)
Journal of Experimental Medicine
, vol.197
, Issue.9
, pp. 1107-1117
-
-
Gantner, B.N.1
Simmons, R.M.2
Canavera, S.J.3
Akira, S.4
Underhill, D.M.5
-
31
-
-
34548459868
-
Structure and function of Toll receptors and their ligands
-
1:CAS:528:DC%2BD2sXhtVehtb7J 10.1146/annurev.biochem.76.060305.151318 17362201
-
NJ Gay M Gangloff 2007 Structure and function of Toll receptors and their ligands Annu Rev Biochem 76 141 165 1:CAS:528:DC%2BD2sXhtVehtb7J 10.1146/annurev.biochem.76.060305.151318 17362201
-
(2007)
Annu Rev Biochem
, vol.76
, pp. 141-165
-
-
Gay, N.J.1
Gangloff, M.2
-
32
-
-
0035881675
-
Cutting edge: Bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression
-
1:CAS:528:DC%2BD3MXlvFeqt7Y%3D 11489966
-
AT Gewirtz TA Navas S Lyons PJ Godowski JL Madara 2001 Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression J Immunol 167 1882 1885 1:CAS:528: DC%2BD3MXlvFeqt7Y%3D 11489966
-
(2001)
J Immunol
, vol.167
, pp. 1882-1885
-
-
Gewirtz, A.T.1
Navas, T.A.2
Lyons, S.3
Godowski, P.J.4
Madara, J.L.5
-
33
-
-
1642529500
-
Isolation of an endotoxin-MD-2 complex that produces Toll-like receptor 4-dependent cell activation at picomolar concentrations
-
DOI 10.1073/pnas.0306906101
-
TL Gioannini A Teghanemt D Zhang NP Coussens W Dockstader S Ramaswamy JP Weiss 2004 Isolation of an endotoxin-MD-2 complex that produces Toll-like receptor 4-dependent cell activation at picomolar concentrations Proc Natl Acad Sci USA 101 4186 4191 1:CAS:528:DC%2BD2cXivFart70%3D 10.1073/pnas.0306906101 15010525 (Pubitemid 38405904)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.12
, pp. 4186-4191
-
-
Gioannini, T.L.1
Teghanemt, A.2
Zhang, D.3
Coussens, N.P.4
Dockstader, W.5
Ramaswamy, S.6
Weiss, J.P.7
-
34
-
-
0037439663
-
Lipopolysaccharides from Legionella and Rhizobium stimulate mouse bone marrow granulacytes via Toll-like receptor 2
-
DOI 10.1242/jcs.00212
-
R Girard T Pedron S Uematsu V Balloy M Chignard S Akira R Chaby 2003 Lipopolysaccharides from Legionella and Rhizobium stimulate mouse bone marrow granulocytes via Toll-like receptor 2 J Cell Sci 116 293 302 1:CAS:528:DC%2BD3sXpvVKntw%3D%3D 10.1242/jcs.00212 12482915 (Pubitemid 36163870)
-
(2003)
Journal of Cell Science
, vol.116
, Issue.2
, pp. 293-302
-
-
Girard, R.1
Pedron, T.2
Uematsu, S.3
Balloy, V.4
Chignard, M.5
Akira, S.6
Chaby, R.7
-
35
-
-
20644467242
-
A smooth operator for LPS responses
-
DOI 10.1038/ni0605-544
-
PJ Godowski 2005 A smooth operator for LPS responses Nat Immunol 6 544 546 1:CAS:528:DC%2BD2MXktlWitr8%3D 10.1038/ni0605-544 15908933 (Pubitemid 41710722)
-
(2005)
Nature Immunology
, vol.6
, Issue.6
, pp. 544-546
-
-
Godowski, P.J.1
-
36
-
-
2342497250
-
Type-A CpG oligonucleotides activate exclusively porcine natural interferon-producing cells to secrete interferon-α, tumour necrosis factor-α and interleukin-12
-
DOI 10.1111/j.1365-2567.2004.01856.x
-
L Guzylack-Piriou C Balmelli KC McCullough A Summerfield 2004 Type-A CpG oligonucleotides activate exclusively porcine natural interferon-producing cells to secrete interferon-alpha, tumour necrosis factor-alpha and interleukin-12 Immunology 112 28 37 1:CAS:528:DC%2BD2cXktFKgu7c%3D 10.1111/j.1365-2567.2004. 01856.x 15096181 (Pubitemid 38609819)
-
(2004)
Immunology
, vol.112
, Issue.1
, pp. 28-37
-
-
Guzylack-Piriou, L.1
Balmelli, C.2
Mccullough, K.C.3
Summerfield, A.4
-
37
-
-
20044368019
-
Human TLR10 is a functional receptor, expressed by B cells and plasmacytoid dendritic cells, which activates gene transcription through MyD88
-
1:CAS:528:DC%2BD2MXhsFeqsbc%3D 15728506
-
U Hasan C Chaffois C Gaillard V Saulnier E Merck S Tancredi C Guiet F Briere J Vlach S Lebecque G Trinchieri EE Bates 2005 Human TLR10 is a functional receptor, expressed by B cells and plasmacytoid dendritic cells, which activates gene transcription through MyD88 J Immunol 174 2942 2950 1:CAS:528:DC%2BD2MXhsFeqsbc%3D 15728506
-
(2005)
J Immunol
, vol.174
, pp. 2942-2950
-
-
Hasan, U.1
Chaffois, C.2
Gaillard, C.3
Saulnier, V.4
Merck, E.5
Tancredi, S.6
Guiet, C.7
Briere, F.8
Vlach, J.9
Lebecque, S.10
Trinchieri, G.11
Bates, E.E.12
-
38
-
-
0042315392
-
Murein lipoprotein, peptidoglycan-associated lipoprotein, and outer membrane protein A are present in purified rough and smooth lipopolysaccharides
-
DOI 10.1086/376453
-
J Hellman MM Tehan HS Warren 2003 Murein lipoprotein, peptidoglycan-associated lipoprotein, and outer membrane protein A are present in purified rough and smooth lipopolysaccharides J Infect Dis 188 286 289 1:CAS:528:DC%2BD3sXmslShtbs%3D 10.1086/376453 12854085 (Pubitemid 36898162)
-
(2003)
Journal of Infectious Diseases
, vol.188
, Issue.2
, pp. 286-289
-
-
Hellman, J.1
Tehan, M.M.2
Warren, H.S.3
-
39
-
-
0033198204
-
Cutting edge: Inflammatory signaling by Borrelia burgdorferi lipoproteins is mediated by toll-like receptor 2
-
1:CAS:528:DyaK1MXls1Krs78%3D 10452971
-
M Hirschfeld CJ Kirschning R Schwandner H Wesche JH Weis RM Wooten JJ Weis 1999 Cutting edge: inflammatory signaling by Borrelia burgdorferi lipoproteins is mediated by toll-like receptor 2 J Immunol 163 2382 2386 1:CAS:528:DyaK1MXls1Krs78%3D 10452971
-
(1999)
J Immunol
, vol.163
, pp. 2382-2386
-
-
Hirschfeld, M.1
Kirschning, C.J.2
Schwandner, R.3
Wesche, H.4
Weis, J.H.5
Wooten, R.M.6
Weis, J.J.7
-
40
-
-
0035115080
-
Signaling by Toll-like receptor 2 and 4 agonists results in differential gene expression in murine macrophages
-
DOI 10.1128/IAI.69.3.1477-1482.2001
-
M Hirschfeld JJ Weis V Toshchakov CA Salkowski MJ Cody DC Ward N Qureshi SM Michalek SN Vogel 2001 Signaling by toll-like receptor 2 and 4 agonists results in differential gene expression in murine macrophages Infect Immun 69 1477 1482 1:CAS:528:DC%2BD3MXitFGrt7c%3D 10.1128/IAI.69.3.1477-1482.2001 11179315 (Pubitemid 32187597)
-
(2001)
Infection and Immunity
, vol.69
, Issue.3
, pp. 1477-1482
-
-
Hirschfeld, M.1
Weis, J.J.2
Toshchakov, V.3
Salkowski, C.A.4
Cody, M.J.5
Ward, D.C.6
Qureshi, N.7
Michalek, S.M.8
Vogel, S.N.9
-
41
-
-
13444280215
-
CD36 is a sensor of diacylglycerides
-
DOI 10.1038/nature03253
-
K Hoebe P Georgel S Rutschmann X Du S Mudd K Crozat S Sovath L Shamel T Hartung U Zahringer B Beutler 2005 CD36 is a sensor of diacylglycerides Nature 433 523 527 1:CAS:528:DC%2BD2MXpt1Clsw%3D%3D 10.1038/nature03253 15690042 (Pubitemid 40204309)
-
(2005)
Nature
, vol.433
, Issue.7025
, pp. 523-527
-
-
Hoebe, K.1
Georgel, P.2
Rutschmann, S.3
Du, X.4
Mudd, S.5
Crozat, K.6
Sovath, S.7
Shamel, L.8
Hartung, T.9
Zahringer, U.10
Beutler, B.11
-
42
-
-
40549107436
-
Targeting Toll-like receptor signaling pathways for design of novel immune therapeutics
-
DOI 10.2174/157016308783769441
-
E Hong-Geller A Chaudhary S Lauer 2008 Targeting toll-like receptor signaling pathways for design of novel immune therapeutics Curr Drug Discov Technol 5 29 38 1:CAS:528:DC%2BD1cXksVGksLo%3D 10.2174/157016308783769441 18537565 (Pubitemid 351364571)
-
(2008)
Current Drug Discovery Technologies
, vol.5
, Issue.1
, pp. 29-38
-
-
Hong-Geller, E.1
Chaudhary, A.2
Lauer, S.3
-
43
-
-
37449031125
-
Potent immunogenicity and efficacy of a universal influenza vaccine candidate comprising a recombinant fusion protein linking influenza M2e to the TLR5 ligand flagellin
-
DOI 10.1016/j.vaccine.2007.10.062, PII S0264410X0701256X
-
JW Huleatt V Nakaar P Desai Y Huang D Hewitt A Jacobs J Tang W McDonald L Song RK Evans S Umlauf L Tussey TJ Powell 2008 Potent immunogenicity and efficacy of a universal influenza vaccine candidate comprising a recombinant fusion protein linking influenza M2e to the TLR5 ligand flagellin Vaccine 26 201 214 1:CAS:528:DC%2BD1cXhtF2hsA%3D%3D 10.1016/j.vaccine.2007.10.062 18063235 (Pubitemid 50008089)
-
(2008)
Vaccine
, vol.26
, Issue.2
, pp. 201-214
-
-
Huleatt, J.W.1
Nakaar, V.2
Desai, P.3
Huang, Y.4
Hewitt, D.5
Jacobs, A.6
Tang, J.7
McDonald, W.8
Song, L.9
Evans, R.K.10
Umlauf, S.11
Tussey, L.12
Powell, T.J.13
-
44
-
-
24144492673
-
Safety of CpG oligodeoxynucleotides in veterinary species
-
1:CAS:528:DC%2BD3sXmvVOmsr0%3D 10.1089/108729003768247628 12954116
-
XP Ioannou P Griebel A Mena SM Gomis DL Godson G Mutwiri R Hecker LA Babiuk S van Drunen Littel-van den Hurk 2003 Safety of CpG oligodeoxynucleotides in veterinary species Antisense Nucleic Acid Drug Dev 13 157 167 1:CAS:528:DC%2BD3sXmvVOmsr0%3D 10.1089/108729003768247628 12954116
-
(2003)
Antisense Nucleic Acid Drug Dev
, vol.13
, pp. 157-167
-
-
Ioannou, X.P.1
Griebel, P.2
Mena, A.3
Gomis, S.M.4
Godson, D.L.5
Mutwiri, G.6
Hecker, R.7
Babiuk, L.A.8
Van Drunen Littel-Van Den Hurk, S.9
-
45
-
-
35349002727
-
E6020: A synthetic Toll-like receptor 4 agonist as a vaccine adjuvant
-
DOI 10.1586/14760584.6.5.773
-
ST Ishizaka LD Hawkins 2007 E6020: a synthetic Toll-like receptor 4 agonist as a vaccine adjuvant Expert Rev Vaccines 6 773 784 1:CAS:528: DC%2BD2sXhtFGgsrrO 10.1586/14760584.6.5.773 17931157 (Pubitemid 47607852)
-
(2007)
Expert Review of Vaccines
, vol.6
, Issue.5
, pp. 773-784
-
-
Ishizaka, S.T.1
Hawkins, L.D.2
-
46
-
-
47149099757
-
Phagocytosis and intracellular killing of MD-2 opsonized gram-negative bacteria depend on TLR4 signaling
-
1:CAS:528:DC%2BD1cXlsVSrs7w%3D 10.1182/blood-2007-11-126862 18203953
-
V Jain A Halle KA Halmen E Lien M Charrel-Dennis S Ram DT Golenbock A Visintin 2008 Phagocytosis and intracellular killing of MD-2 opsonized gram-negative bacteria depend on TLR4 signaling Blood 111 4637 4645 1:CAS:528:DC%2BD1cXlsVSrs7w%3D 10.1182/blood-2007-11-126862 18203953
-
(2008)
Blood
, vol.111
, pp. 4637-4645
-
-
Jain, V.1
Halle, A.2
Halmen, K.A.3
Lien, E.4
Charrel-Dennis, M.5
Ram, S.6
Golenbock, D.T.7
Visintin, A.8
-
47
-
-
20644469429
-
CD14 is required for MyD88-independent LPS signaling
-
DOI 10.1038/ni1207
-
Z Jiang P Georgel X Du L Shamel S Sovath S Mudd M Huber C Kalis S Keck C Galanos M Freudenberg B Beutler 2005 CD14 is required for MyD88-independent LPS signaling Nat Immunol 6 565 570 1:CAS:528:DC%2BD2MXktlWit7o%3D 10.1038/ni1207 15895089 (Pubitemid 41710726)
-
(2005)
Nature Immunology
, vol.6
, Issue.6
, pp. 565-570
-
-
Jiang, Z.1
Georgel, P.2
Du, X.3
Shamel, L.4
Sovath, S.5
Mudd, S.6
Huber, M.7
Kalis, C.8
Keck, S.9
Galanos, C.10
Freudenberg, M.11
Beutler, B.12
-
48
-
-
34548608447
-
Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide
-
DOI 10.1016/j.cell.2007.09.008, PII S009286740701152X
-
MS Jin SE Kim JY Heo ME Lee HM Kim SG Paik H Lee JO Lee 2007 Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide Cell 130 1071 1082 1:CAS:528:DC%2BD2sXhtFKnurvE 10.1016/j.cell.2007. 09.008 17889651 (Pubitemid 47410281)
-
(2007)
Cell
, vol.130
, Issue.6
, pp. 1071-1082
-
-
Jin, M.S.1
Kim, S.E.2
Heo, J.Y.3
Lee, M.E.4
Kim, H.M.5
Paik, S.-G.6
Lee, H.7
Lee, J.-O.8
-
50
-
-
34248672889
-
Antiviral signaling through pattern recognition receptors
-
DOI 10.1093/jb/mvm032
-
T Kawai S Akira 2007 Antiviral signaling through pattern recognition receptors J Biochem 141 137 145 1:CAS:528:DC%2BD2sXltF2it7w%3D 10.1093/jb/mvm032 17190786 (Pubitemid 46775751)
-
(2007)
Journal of Biochemistry
, vol.141
, Issue.2
, pp. 137-145
-
-
Kawai, T.1
Akira, S.2
-
51
-
-
37349057372
-
Functional characterization of chicken TLR5 reveals species-specific recognition of flagellin
-
DOI 10.1016/j.molimm.2007.09.013, PII S0161589007007481
-
AM Keestra MR de Zoete RA van Aubel JP van Putten 2008 Functional characterization of chicken TLR5 reveals species-specific recognition of flagellin Mol Immunol 45 1298 1307 1:CAS:528:DC%2BD1cXhtF2ntg%3D%3D 10.1016/j.molimm.2007.09.013 17964652 (Pubitemid 350299485)
-
(2008)
Molecular Immunology
, vol.45
, Issue.5
, pp. 1298-1307
-
-
Keestra, A.M.1
De Zoete, M.R.2
Van Aubel, R.A.M.H.3
Van Putten, J.P.M.4
-
52
-
-
34548222514
-
Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran
-
DOI 10.1016/j.cell.2007.08.002, PII S0092867407010215
-
HM Kim BS Park JI Kim SE Kim J Lee SC Oh P Enkhbayar N Matsushima H Lee OJ Yoo JO Lee 2007 Crystal structure of the TLR4-MD-2 complex with bound endotoxin antagonist Eritoran Cell 130 906 917 1:CAS:528:DC%2BD2sXhtV2ntLzN 10.1016/j.cell.2007.08.002 17803912 (Pubitemid 47332573)
-
(2007)
Cell
, vol.130
, Issue.5
, pp. 906-917
-
-
Kim, H.M.1
Park, B.S.2
Kim, J.-I.3
Kim, S.E.4
Lee, J.5
Oh, S.C.6
Enkhbayar, P.7
Matsushima, N.8
Lee, H.9
Yoo, O.J.10
Lee, J.-O.11
-
53
-
-
0031774181
-
Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide
-
DOI 10.1084/jem.188.11.2091
-
CJ Kirschning H Wesche T Merrill Ayres M Rothe 1998 Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide J Exp Med 188 2091 2097 1:CAS:528:DyaK1cXnvFOhu7o%3D 10.1084/jem.188.11.2091 9841923 (Pubitemid 28562526)
-
(1998)
Journal of Experimental Medicine
, vol.188
, Issue.11
, pp. 2091-2097
-
-
Kirschning, C.J.1
Wesche, H.2
Merrill Ayres, T.3
Rothe, M.4
-
54
-
-
5944261457
-
Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus
-
1:CAS:528:DC%2BD3cXnvVGht78%3D 10.1038/80833 11062499
-
EA Kurt-Jones L Popova L Kwinn LM Haynes LP Jones RA Tripp EE Walsh MW Freeman DT Golenbock LJ Anderson RW Finberg 2000 Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus Nat Immunol 1 398 401 1:CAS:528:DC%2BD3cXnvVGht78%3D 10.1038/80833 11062499
-
(2000)
Nat Immunol
, vol.1
, pp. 398-401
-
-
Kurt-Jones, E.A.1
Popova, L.2
Kwinn, L.3
Haynes, L.M.4
Jones, L.P.5
Tripp, R.A.6
Walsh, E.E.7
Freeman, M.W.8
Golenbock, D.T.9
Anderson, L.J.10
Finberg, R.W.11
-
55
-
-
0037090077
-
Two lipoproteins extracted from Escherichia coli K-12 LCD25 lipopolysaccharide are the major components responsible for Toll-like receptor 2-mediated signaling
-
1:CAS:528:DC%2BD38XivV2is7g%3D 11937558
-
HK Lee J Lee PS Tobias 2002 Two lipoproteins extracted from Escherichia coli K-12 LCD25 lipopolysaccharide are the major components responsible for Toll-like receptor 2-mediated signaling J Immunol 168 4012 4017 1:CAS:528:DC%2BD38XivV2is7g%3D 11937558
-
(2002)
J Immunol
, vol.168
, pp. 4012-4017
-
-
Lee, H.K.1
Lee, J.2
Tobias, P.S.3
-
56
-
-
0034002247
-
Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide
-
1:CAS:528:DC%2BD3cXhtlygu7c%3D 10.1172/JCI8541 10683379
-
E Lien TK Means H Heine A Yoshimura S Kusumoto K Fukase MJ Fenton M Oikawa N Qureshi B Monks RW Finberg RR Ingalls DT Golenbock 2000 Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide J Clin Invest 105 497 504 1:CAS:528:DC%2BD3cXhtlygu7c%3D 10.1172/JCI8541 10683379
-
(2000)
J Clin Invest
, vol.105
, pp. 497-504
-
-
Lien, E.1
Means, T.K.2
Heine, H.3
Yoshimura, A.4
Kusumoto, S.5
Fukase, K.6
Fenton, M.J.7
Oikawa, M.8
Qureshi, N.9
Monks, B.10
Finberg, R.W.11
Ingalls, R.R.12
Golenbock, D.T.13
-
57
-
-
42349090335
-
Structural basis of toll-like receptor 3 signaling with double-stranded RNA
-
DOI 10.1126/science.1155406
-
L Liu I Botos Y Wang JN Leonard J Shiloach DM Segal DR Davies 2008 Structural basis of toll-like receptor 3 signaling with double-stranded RNA Science 320 379 381 1:CAS:528:DC%2BD1cXks1GhsLk%3D 10.1126/science.1155406 18420935 (Pubitemid 351555661)
-
(2008)
Science
, vol.320
, Issue.5874
, pp. 379-381
-
-
Liu, L.1
Botos, I.2
Wang, Y.3
Leonard, J.N.4
Shiloach, J.5
Segal, D.M.6
Davies, D.R.7
-
58
-
-
58949092384
-
Host species-specific usage of the TLR4-LPS receptor complex
-
1:CAS:528:DC%2BD1cXhtVKnurzL 10.1177/1753425908095957 18669608
-
R Lizundia KS Sauter G Taylor D Werling 2008 Host species-specific usage of the TLR4-LPS receptor complex Innate Immun 14 223 231 1:CAS:528: DC%2BD1cXhtVKnurzL 10.1177/1753425908095957 18669608
-
(2008)
Innate Immun
, vol.14
, pp. 223-231
-
-
Lizundia, R.1
Sauter, K.S.2
Taylor, G.3
Werling, D.4
-
59
-
-
35448968699
-
The equine TLR4/MD-2 complex mediates recognition of lipopolysaccharide from Rhodobacter sphaeroides as an agonist
-
DOI 10.1177/0968051907083193
-
KL Lohmann ML Vandenplas MH Barton CE Bryant JN Moore 2007 The equine TLR4/MD-2 complex mediates recognition of lipopolysaccharide from Rhodobacter sphaeroides as an agonist J Endotoxin Res 13 235 242 1:CAS:528: DC%2BD2sXhtVKqsbbE 10.1177/0968051907083193 17956942 (Pubitemid 47618262)
-
(2007)
Journal of Endotoxin Research
, vol.13
, Issue.4
, pp. 235-242
-
-
Lohmann, K.L.1
Vandenplas, M.L.2
Barton, M.H.3
Bryant, C.E.4
Moore, J.N.5
-
60
-
-
0030831210
-
A human homologue of the Drosophila toll protein signals activation of adaptive immunity
-
DOI 10.1038/41131
-
R Medzhitov P Preston-Hurlburt CA Janeway Jr 1997 A human homologue of the Drosophila Toll protein signals activation of adaptive immunity Nature 388 394 397 1:CAS:528:DyaK2sXkvVChurc%3D 10.1038/41131 9237759 (Pubitemid 27334820)
-
(1997)
Nature
, vol.388
, Issue.6640
, pp. 394-397
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Janeway Jr., C.A.3
-
61
-
-
0242557470
-
Bovine and Ovine Blood Mononuclear Leukocytes Differ Markedly in Innate Immune Responses Induced by Class A and Class B CpG-Oligodeoxynucleotide
-
A Mena AK Nichani Y Popowych XP Ioannou DL Godson GK Mutwiri R Hecker LA Babiuk P Griebel 2003 Bovine and ovine blood mononuclear leukocytes differ markedly in innate immune responses induced by Class A and Class B CpG-oligodeoxynucleotide Oligonucleotides 13 245 259 1:CAS:528: DC%2BD3sXos1CmtLw%3D 10.1089/154545703322460621 15000839 (Pubitemid 37428816)
-
(2003)
Oligonucleotides
, vol.13
, Issue.4
, pp. 245-259
-
-
Mena, A.1
Nichani, A.K.2
Popowych, Y.3
Ioannou, X.P.4
Godson, D.L.5
Mutwiri, G.K.6
Hecker, R.7
Babiuk, L.A.8
Griebel, P.9
-
62
-
-
0037372661
-
Inhibition of endotoxin response by E5564, a novel toll-like receptor 4-directed endotoxin antagonist
-
DOI 10.1124/jpet.102.044487
-
M Mullarkey JR Rose J Bristol T Kawata A Kimura S Kobayashi M Przetak J Chow F Gusovsky WJ Christ DP Rossignol 2003 Inhibition of endotoxin response by e5564, a novel Toll-like receptor 4-directed endotoxin antagonist J Pharmacol Exp Ther 304 1093 1102 1:CAS:528:DC%2BD3sXit1eisrg%3D 10.1124/jpet.102.044487 12604686 (Pubitemid 36254422)
-
(2003)
Journal of Pharmacology and Experimental Therapeutics
, vol.304
, Issue.3
, pp. 1093-1102
-
-
Mullarkey, M.1
Rose, J.R.2
Bristol, J.3
Kawata, T.4
Kimura, A.5
Kobayashi, S.6
Przetak, M.7
Chow, J.8
Gusovsky, F.9
Christ, W.J.10
Rossignol, D.P.11
-
63
-
-
0036840405
-
The polysaccharide portion plays an indispensable role in Salmonella lipopolysaccharide-induced activation of NF-κB through human toll-like receptor 4
-
DOI 10.1128/IAI.70.11.6043-6047.2002
-
M Muroi K Tanamoto 2002 The polysaccharide portion plays an indispensable role in Salmonella lipopolysaccharide-induced activation of NF-kappaB through human toll-like receptor 4 Infect Immun 70 6043 6047 1:CAS:528: DC%2BD38XotFGks7Y%3D 10.1128/IAI.70.11.6043-6047.2002 12379680 (Pubitemid 35192693)
-
(2002)
Infection and Immunity
, vol.70
, Issue.11
, pp. 6043-6047
-
-
Muroi, M.1
Tanamoto, K.-I.2
-
64
-
-
12244274967
-
Biological activity of immunostimulatory CpG DNA motifs in domestic animals
-
DOI 10.1016/S0165-2427(02)00246-5, PII S0165242702002465
-
G Mutwiri R Pontarollo S Babiuk P Griebel S van Drunen Littel-van den Hurk A Mena C Tsang V Alcon A Nichani X Loannou S Gomis H Townsend R Hecker A Potter LA Babiuk 2003 Biological activity of immunostimulatory CpG DNA motifs in domestic animals Vet Immunol Immunopathol 91 89 103 1:CAS:528: DC%2BD3sXkvV2quw%3D%3D 10.1016/S0165-2427(02)00246-5 12543546 (Pubitemid 36113256)
-
(2003)
Veterinary Immunology and Immunopathology
, vol.91
, Issue.2
, pp. 89-103
-
-
Mutwiri, G.1
Pontarollo, R.2
Babiuk, S.3
Griebel, P.4
Van Drunen Littel-Van Den Hurk, S.5
Mena, A.6
Tsang, C.7
Alcon, V.8
Nichani, A.9
Ioannou, X.10
Gomis, S.11
Townsend, H.12
Hecker, R.13
Potter, A.14
Babiuk, L.A.15
-
65
-
-
78650226557
-
Subcutaneous, but not intratracheal administration of the TLR9 agonist, CpG DNA transiently reduces parainfluenza-3 virus shedding in newborn lambs
-
doi: 10.1016/j.cimid.2010.06.003
-
Nichani AK, Dar MA, Mirakhur KK, Krieg AM, Booth JS, Townsend HG, Potter AA, Babiuk LA, Mutwiri GK (2010) Subcutaneous, but not intratracheal administration of the TLR9 agonist, CpG DNA transiently reduces parainfluenza-3 virus shedding in newborn lambs. Comp Immunol Microbiol Infect Dis. doi: 10.1016/j.cimid.2010.06.003
-
(2010)
Comp Immunol Microbiol Infect Dis.
-
-
Nichani, A.K.1
Dar, M.A.2
Mirakhur, K.K.3
Krieg, A.M.4
Booth, J.S.5
Townsend, H.G.6
Potter, A.A.7
Babiuk, L.A.8
Mutwiri, G.K.9
-
66
-
-
34247566510
-
The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
-
DOI 10.1038/nri2079, PII NRI2079
-
LA O'Neill AG Bowie 2007 The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling Nat Rev Immunol 7 353 364 10.1038/nri2079 17457343 (Pubitemid 46674493)
-
(2007)
Nature Reviews Immunology
, vol.7
, Issue.5
, pp. 353-364
-
-
O'Neill, L.A.J.1
Bowie, A.G.2
-
67
-
-
67649422321
-
Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer
-
10.1124/pr.109.001073 19474110
-
LA O'Neill CE Bryant SL Doyle 2009 Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer Pharmacol Rev 61 177 197 10.1124/pr.109.001073 19474110
-
(2009)
Pharmacol Rev
, vol.61
, pp. 177-197
-
-
O'Neill, L.A.1
Bryant, C.E.2
Doyle, S.L.3
-
68
-
-
0035971217
-
The extra domain A of fibronectin activates Toll-like receptor 4
-
1:CAS:528:DC%2BD3MXis1Okt78%3D 10.1074/jbc.M100099200 11150311
-
Y Okamura M Watari ES Jerud DW Young ST Ishizaka J Rose JC Chow JF Strauss 3rd 2001 The extra domain A of fibronectin activates Toll-like receptor 4 J Biol Chem 276 10229 10233 1:CAS:528:DC%2BD3MXis1Okt78%3D 10.1074/jbc.M100099200 11150311
-
(2001)
J Biol Chem
, vol.276
, pp. 10229-10233
-
-
Okamura, Y.1
Watari, M.2
Jerud, E.S.3
Young, D.W.4
Ishizaka, S.T.5
Rose, J.6
Chow, J.C.7
Strauss III, J.F.8
-
69
-
-
0034610291
-
The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors
-
1:CAS:528:DC%2BD3cXoslyns7w%3D 10.1073/pnas.250476497 11095740
-
A Ozinsky DM Underhill JD Fontenot AM Hajjar KD Smith CB Wilson L Schroeder A Aderem 2000 The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors Proc Natl Acad Sci USA 97 13766 13771 1:CAS:528:DC%2BD3cXoslyns7w%3D 10.1073/pnas.250476497 11095740
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 13766-13771
-
-
Ozinsky, A.1
Underhill, D.M.2
Fontenot, J.D.3
Hajjar, A.M.4
Smith, K.D.5
Wilson, C.B.6
Schroeder, L.7
Aderem, A.8
-
70
-
-
67349182481
-
The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex
-
1:CAS:528:DC%2BD1MXisVOrtLk%3D 10.1038/nature07830 19252480
-
BS Park DH Song HM Kim BS Choi H Lee JO Lee 2009 The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex Nature 458 1191 1195 1:CAS:528:DC%2BD1MXisVOrtLk%3D 10.1038/nature07830 19252480
-
(2009)
Nature
, vol.458
, pp. 1191-1195
-
-
Park, B.S.1
Song, D.H.2
Kim, H.M.3
Choi, B.S.4
Lee, H.5
Lee, J.O.6
-
71
-
-
38649123396
-
The future of toll-like receptor therapeutics
-
1:CAS:528:DC%2BD1cXivF2jsLc%3D 18228178
-
T Parkinson 2008 The future of toll-like receptor therapeutics Curr Opin Mol Ther 10 21 31 1:CAS:528:DC%2BD1cXivF2jsLc%3D 18228178
-
(2008)
Curr Opin Mol Ther
, vol.10
, pp. 21-31
-
-
Parkinson, T.1
-
72
-
-
44449143574
-
Plasmacytoid dendritic cells migrate in afferent skin lymph
-
1:CAS:528:DC%2BD1cXkvVCjs7k%3D 18424716
-
F Pascale V Contreras M Bonneau A Courbet S Chilmonczyk C Bevilacqua M Epardaud V Niborski S Riffault AM Balazuc E Foulon L Guzylack-Piriou B Riteau J Hope N Bertho B Charley I Schwartz-Cornil 2008 Plasmacytoid dendritic cells migrate in afferent skin lymph J Immunol 180 5963 5972 1:CAS:528: DC%2BD1cXkvVCjs7k%3D 18424716
-
(2008)
J Immunol
, vol.180
, pp. 5963-5972
-
-
Pascale, F.1
Contreras, V.2
Bonneau, M.3
Courbet, A.4
Chilmonczyk, S.5
Bevilacqua, C.6
Epardaud, M.7
Niborski, V.8
Riffault, S.9
Balazuc, A.M.10
Foulon, E.11
Guzylack-Piriou, L.12
Riteau, B.13
Hope, J.14
Bertho, N.15
Charley, B.16
Schwartz-Cornil, I.17
-
73
-
-
0037951693
-
BVDV and innate immunity
-
DOI 10.1016/S1045-1056(03)00024-1
-
E Peterhans TW Jungi M Schweizer 2003 BVDV and innate immunity Biologicals 31 107 112 1:CAS:528:DC%2BD3sXktFWgsr0%3D 10.1016/S1045-1056(03) 00024-1 12770540 (Pubitemid 36593345)
-
(2003)
Biologicals
, vol.31
, Issue.2
, pp. 107-111
-
-
Peterhans, E.1
Jungi, T.W.2
Schweizer, M.3
-
74
-
-
0035997382
-
Lipopolysaccharide endotoxins
-
DOI 10.1146/annurev.biochem.71.110601.135414
-
CR Raetz C Whitfield 2002 Lipopolysaccharide endotoxins Annu Rev Biochem 71 635 700 1:CAS:528:DC%2BD38Xos1Clt7w%3D 10.1146/annurev.biochem.71.110601. 135414 12045108 (Pubitemid 34800232)
-
(2002)
Annual Review of Biochemistry
, vol.71
, pp. 635-700
-
-
Raetz, C.R.H.1
Whitfield, C.2
-
75
-
-
0017108014
-
A phase I-II trial of multiple-dose polyriboinosic-polyribocytidylic acid in patieonts with leukemia or solid tumors
-
1:STN:280:DyaE2s%2FjtFOmuw%3D%3D 978771
-
RA Robinson VT DeVita HB Levy S Baron SP Hubbard AS Levine 1976 A phase I-II trial of multiple-dose polyriboinosic-polyribocytidylic acid in patieonts with leukemia or solid tumors J Natl Cancer Inst 57 599 602 1:STN:280: DyaE2s%2FjtFOmuw%3D%3D 978771
-
(1976)
J Natl Cancer Inst
, vol.57
, pp. 599-602
-
-
Robinson, R.A.1
Devita, V.T.2
Levy, H.B.3
Baron, S.4
Hubbard, S.P.5
Levine, A.S.6
-
76
-
-
34250726974
-
Stable transduction of bovine TLR4 and bovine MD-2 into LPS-nonresponsive cells and soluble CD14 promote the ability to respond to LPS
-
DOI 10.1016/j.vetimm.2007.04.017, PII S0165242707001444
-
KS Sauter M Brcic M Franchini TW Jungi 2007 Stable transduction of bovine TLR4 and bovine MD-2 into LPS-nonresponsive cells and soluble CD14 promote the ability to respond to LPS Vet Immunol Immunopathol 118 92 104 1:CAS:528:DC%2BD2sXmvVKlt7k%3D 10.1016/j.vetimm.2007.04.017 17559944 (Pubitemid 46962709)
-
(2007)
Veterinary Immunology and Immunopathology
, vol.118
, Issue.1-2
, pp. 92-104
-
-
Sauter, K.-S.1
Brcic, M.2
Franchini, M.3
Jungi, T.W.4
-
77
-
-
0025107568
-
Structure and function of lipopolysaccharide binding protein
-
1:CAS:528:DyaK3MXhtF2rsrY%3D 10.1126/science.2402637 2402637
-
RR Schumann SR Leong GW Flaggs PW Gray SD Wright JC Mathison PS Tobias RJ Ulevitch 1990 Structure and function of lipopolysaccharide binding protein Science 249 1429 1431 1:CAS:528:DyaK3MXhtF2rsrY%3D 10.1126/science.2402637 2402637
-
(1990)
Science
, vol.249
, pp. 1429-1431
-
-
Schumann, R.R.1
Leong, S.R.2
Flaggs, G.W.3
Gray, P.W.4
Wright, S.D.5
Mathison, J.C.6
Tobias, P.S.7
Ulevitch, R.J.8
-
78
-
-
33847135357
-
Chicken toll-like receptor 3 recognizes its cognate ligand when ectopically expressed in human cells
-
DOI 10.1089/jir.2006.0098
-
H Schwarz K Schneider A Ohnemus M Lavric S Kothlow S Bauer B Kaspers P Staeheli 2007 Chicken toll-like receptor 3 recognizes its cognate ligand when ectopically expressed in human cells J Interferon Cytokine Res 27 97 101 1:CAS:528:DC%2BD2sXitVGru7g%3D 10.1089/jir.2006.0098 17316136 (Pubitemid 46294431)
-
(2007)
Journal of Interferon and Cytokine Research
, vol.27
, Issue.2
, pp. 97-101
-
-
Schwarz, H.1
Schneider, K.2
Ohnemus, A.3
Lavric, M.4
Kothlow, S.5
Bauer, S.6
Kaspers, B.7
Staeheli, P.8
-
79
-
-
0034969224
-
Immunostimulatory CpG-modified plasmid DNA enhances IL-12, TNF-alpha, and NO production by bovine macrophages
-
1:CAS:528:DC%2BD3MXlt1ars7o%3D 11435492
-
LK Shoda KA Kegerreis CE Suarez W Mwangi DP Knowles WC Brown 2001 Immunostimulatory CpG-modified plasmid DNA enhances IL-12, TNF-alpha, and NO production by bovine macrophages J Leukoc Biol 70 103 112 1:CAS:528: DC%2BD3MXlt1ars7o%3D 11435492
-
(2001)
J Leukoc Biol
, vol.70
, pp. 103-112
-
-
Shoda, L.K.1
Kegerreis, K.A.2
Suarez, C.E.3
Mwangi, W.4
Knowles, D.P.5
Brown, W.C.6
-
81
-
-
27644533352
-
Toll-like receptor 2 antagonists. Part 1: Preliminary SAR investigation of novel synthetic phospholipids
-
DOI 10.1016/j.bmcl.2005.08.080, PII S0960894X05011248
-
MR Spyvee H Zhang LD Hawkins JC Chow 2005 Toll-like receptor 2 antagonists. Part 1: preliminary SAR investigation of novel synthetic phospholipids Bioorg Med Chem Lett 15 5494 5498 1:CAS:528:DC%2BD2MXhtFOrsL3O 10.1016/j.bmcl.2005.08.080 16236498 (Pubitemid 41562977)
-
(2005)
Bioorganic and Medicinal Chemistry Letters
, vol.15
, Issue.24
, pp. 5494-5498
-
-
Spyvee, M.R.1
Zhang, H.2
Hawkins, L.D.3
Chow, J.C.4
-
82
-
-
2442499153
-
Structure-Activity Relationship of Synthetic Toll-like Receptor 4 Agonists
-
DOI 10.1074/jbc.M310760200
-
AG Stover CJ Da Silva JT Evans CW Cluff MW Elliott EW Jeffery DA Johnson MJ Lacy JR Baldridge P Probst RJ Ulevitch DH Persing RM Hershberg 2004 Structure-activity relationship of synthetic toll-like receptor 4 agonists J Biol Chem 279 4440 4449 10.1074/jbc.M310760200 14570885 (Pubitemid 38199033)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.6
, pp. 4440-4449
-
-
Stover, A.G.1
Da Silva Correia, J.2
Evans, J.T.3
Cluff, C.W.4
Elliott, M.W.5
Jeffery, E.W.6
Johnson, D.A.7
Lacy, M.J.8
Baldridge, J.R.9
Probst, P.10
Ulevitch, R.J.11
Persing, D.H.12
Hershberg, R.M.13
-
83
-
-
54249084609
-
Protection of neonatal broiler chicks against Salmonella Typhimurium septicemia by DNA containing CpG motifs
-
10.1637/8196-121907-Reg 18939626
-
A Taghavi B Allan G Mutwiri A Van Kessel P Willson L Babiuk A Potter S Gomis 2008 Protection of neonatal broiler chicks against Salmonella Typhimurium septicemia by DNA containing CpG motifs Avian Dis 52 398 406 10.1637/8196-121907-Reg 18939626
-
(2008)
Avian Dis
, vol.52
, pp. 398-406
-
-
Taghavi, A.1
Allan, B.2
Mutwiri, G.3
Van Kessel, A.4
Willson, P.5
Babiuk, L.6
Potter, A.7
Gomis, S.8
-
84
-
-
0033213590
-
Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components
-
DOI 10.1016/S1074-7613(00)80119-3
-
O Takeuchi K Hoshino T Kawai H Sanjo H Takada T Ogawa K Takeda S Akira 1999 Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components Immunity 11 443 451 1:CAS:528:DyaK1MXntFCnur4%3D 10.1016/S1074-7613(00)80119-3 10549626 (Pubitemid 29504199)
-
(1999)
Immunity
, vol.11
, Issue.4
, pp. 443-451
-
-
Takeuchi, O.1
Hoshino, K.2
Kawai, T.3
Sanjo, H.4
Takada, H.5
Ogawa, T.6
Takeda, K.7
Akira, S.8
-
85
-
-
0034922923
-
Discrimination of bacterial lipoproteins by Toll-like receptor 6
-
1:CAS:528:DC%2BD3MXlsFOgtbc%3D 10.1093/intimm/13.7.933 11431423
-
O Takeuchi T Kawai PF Muhlradt M Morr JD Radolf A Zychlinsky K Takeda S Akira 2001 Discrimination of bacterial lipoproteins by Toll-like receptor 6 Int Immunol 13 933 940 1:CAS:528:DC%2BD3MXlsFOgtbc%3D 10.1093/intimm/13.7.933 11431423
-
(2001)
Int Immunol
, vol.13
, pp. 933-940
-
-
Takeuchi, O.1
Kawai, T.2
Muhlradt, P.F.3
Morr, M.4
Radolf, J.D.5
Zychlinsky, A.6
Takeda, K.7
Akira, S.8
-
86
-
-
0642371140
-
The Lyme disease vaccine takes its toll
-
10.1089/153036602321653798 12804162
-
V Thomas E Fikrig 2002 The Lyme disease vaccine takes its toll Vector Borne Zoonotic Dis 2 217 222 10.1089/153036602321653798 12804162
-
(2002)
Vector Borne Zoonotic Dis
, vol.2
, pp. 217-222
-
-
Thomas, V.1
Fikrig, E.2
-
87
-
-
0034443265
-
Maturation of human dendritic cells by cell wall skeleton of Mycobacterium boris bacillus Calmette-Guérin: Involvement of toll-like receptors
-
DOI 10.1128/IAI.68.12.6883-6890.2000
-
S Tsuji M Matsumoto O Takeuchi S Akira I Azuma A Hayashi K Toyoshima T Seya 2000 Maturation of human dendritic cells by cell wall skeleton of Mycobacterium bovis bacillus Calmette-Guerin: involvement of toll-like receptors Infect Immun 68 6883 6890 1:CAS:528:DC%2BD3MXjslCktbs%3D 10.1128/IAI.68.12. 6883-6890.2000 11083809 (Pubitemid 32463398)
-
(2000)
Infection and Immunity
, vol.68
, Issue.12
, pp. 6883-6890
-
-
Tsuji, S.1
Matsumoto, M.2
Takeuchi, O.3
Akira, S.4
Azuma, I.5
Hayashi, A.6
Toyoshima, K.7
Seya, T.8
-
88
-
-
34447505084
-
Toll-like receptors and type I Interferons
-
DOI 10.1074/jbc.R700009200
-
S Uematsu S Akira 2007 Toll-like receptors and Type I interferons J Biol Chem 282 15319 15323 1:CAS:528:DC%2BD2sXltl2gtLk%3D 10.1074/jbc.R700009200 17395581 (Pubitemid 47093256)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.21
, pp. 15319-15324
-
-
Uematsu, S.1
Akira, S.2
-
89
-
-
9144238063
-
Characterization of three CpG oligodeoxynucleotide classes with distinct immunostimulatory activities
-
DOI 10.1002/eji.200324032
-
J Vollmer R Weeratna P Payette M Jurk C Schetter M Laucht T Wader S Tluk M Liu HL Davis AM Krieg 2004 Characterization of three CpG oligodeoxynucleotide classes with distinct immunostimulatory activities Eur J Immunol 34 251 262 1:CAS:528:DC%2BD2cXnslymtA%3D%3D 10.1002/eji.200324032 14971051 (Pubitemid 38111541)
-
(2004)
European Journal of Immunology
, vol.34
, Issue.1
, pp. 251-262
-
-
Vollmer, J.1
Weeratna, R.2
Payette, P.3
Jurk, M.4
Schetter, C.5
Laucht, M.6
Wader, T.7
Tluk, S.8
Liu, M.9
Davis, H.L.10
Krieg, A.M.11
-
90
-
-
48749127416
-
Elucidation of the MD-2/TLR4 interface required for signaling by lipid IVa
-
1:CAS:528:DC%2BD1cXotF2rsbY%3D 18606678
-
C Walsh M Gangloff T Monie T Smyth B Wei TJ McKinley D Maskell N Gay C Bryant 2008 Elucidation of the MD-2/TLR4 interface required for signaling by lipid IVa J Immunol 181 1245 1254 1:CAS:528:DC%2BD1cXotF2rsbY%3D 18606678
-
(2008)
J Immunol
, vol.181
, pp. 1245-1254
-
-
Walsh, C.1
Gangloff, M.2
Monie, T.3
Smyth, T.4
Wei, B.5
McKinley, T.J.6
Maskell, D.7
Gay, N.8
Bryant, C.9
-
91
-
-
11144273976
-
Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis
-
DOI 10.1038/nm1140
-
T Wang T Town L Alexopoulou JF Anderson E Fikrig RA Flavell 2004 Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis Nat Med 10 1366 1373 1:CAS:528:DC%2BD2cXhtVCitr7M 10.1038/nm1140 15558055 (Pubitemid 40022719)
-
(2004)
Nature Medicine
, vol.10
, Issue.12
, pp. 1366-1373
-
-
Wang, T.1
Town, T.2
Alexopoulou, L.3
Anderson, J.F.4
Fikrig, E.5
Flavell, R.A.6
-
92
-
-
34548780733
-
Pattern recognition receptors in companion and farm animals - The key to unlocking the door to animal disease?
-
DOI 10.1016/j.tvjl.2006.10.010, PII S1090023306002206
-
D Werling TJ Coffey 2007 Pattern recognition receptors in companion and farm animals - the key to unlocking the door to animal disease? Vet J 174 240 251 1:CAS:528:DC%2BD2sXhtVOgs7vL 10.1016/j.tvjl.2006.10.010 17137812 (Pubitemid 47424135)
-
(2007)
Veterinary Journal
, vol.174
, Issue.2
, pp. 240-251
-
-
Werling, D.1
Coffey, T.J.2
-
93
-
-
61349086647
-
Variation matters: TLR structure and species-specific pathogen recognition
-
1:CAS:528:DC%2BD1MXivVertr4%3D 10.1016/j.it.2008.12.001 19211304
-
D Werling OC Jann V Offord EJ Glass TJ Coffey 2009 Variation matters: TLR structure and species-specific pathogen recognition Trends Immunol 30 124 130 1:CAS:528:DC%2BD1MXivVertr4%3D 10.1016/j.it.2008.12.001 19211304
-
(2009)
Trends Immunol
, vol.30
, pp. 124-130
-
-
Werling, D.1
Jann, O.C.2
Offord, V.3
Glass, E.J.4
Coffey, T.J.5
-
94
-
-
5944225473
-
Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism
-
DOI 10.1038/86354
-
C Werts RI Tapping JC Mathison TH Chuang V Kravchenko I Saint Girons DA Haake PJ Godowski F Hayashi A Ozinsky DM Underhill CJ Kirschning H Wagner A Aderem PS Tobias RJ Ulevitch 2001 Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism Nat Immunol 2 346 352 1:CAS:528: DC%2BD3MXis1aktbw%3D 10.1038/86354 11276206 (Pubitemid 33706346)
-
(2001)
Nature Immunology
, vol.2
, Issue.4
, pp. 346-352
-
-
Werts, C.1
Tapping, R.I.2
Mathison, J.C.3
Chuang, T.-H.4
Kravchenko, V.5
Saint Girons, I.6
Haake, D.A.7
Godowski, P.J.8
Hayashi, F.9
Ozinsky, A.10
Underhill, D.M.11
Kirschning, C.J.12
Wagner, H.13
Aderem, A.14
Tobias, P.S.15
Ulevitch, R.J.16
-
95
-
-
0025166114
-
CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein
-
1:CAS:528:DyaK3MXksV2q 10.1126/science.1698311 1698311
-
SD Wright RA Ramos PS Tobias RJ Ulevitch JC Mathison 1990 CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein Science 249 1431 1433 1:CAS:528:DyaK3MXksV2q 10.1126/science.1698311 1698311
-
(1990)
Science
, vol.249
, pp. 1431-1433
-
-
Wright, S.D.1
Ramos, R.A.2
Tobias, P.S.3
Ulevitch, R.J.4
Mathison, J.C.5
-
96
-
-
43449132981
-
Porcine TLR8 and TLR7 are both activated by a selective TLR7 ligand, imiquimod
-
1:CAS:528:DC%2BD1cXlvFKqsLg%3D 10.1016/j.molimm.2008.02.028 18439678
-
J Zhu K Lai R Brownile LA Babiuk GK Mutwiri 2008 Porcine TLR8 and TLR7 are both activated by a selective TLR7 ligand, imiquimod Mol Immunol 45 3238 3243 1:CAS:528:DC%2BD1cXlvFKqsLg%3D 10.1016/j.molimm.2008.02.028 18439678
-
(2008)
Mol Immunol
, vol.45
, pp. 3238-3243
-
-
Zhu, J.1
Lai, K.2
Brownile, R.3
Babiuk, L.A.4
Mutwiri, G.K.5
-
97
-
-
59249095900
-
Characterization of bovine Toll-like receptor 8: Ligand specificity, signaling essential sites and dimerization
-
1:CAS:528:DC%2BD1MXhsFertrw%3D 10.1016/j.molimm.2008.09.024 18995910
-
J Zhu R Brownlie Q Liu LA Babiuk A Potter GK Mutwiri 2009 Characterization of bovine Toll-like receptor 8: ligand specificity, signaling essential sites and dimerization Mol Immunol 46 978 990 1:CAS:528: DC%2BD1MXhsFertrw%3D 10.1016/j.molimm.2008.09.024 18995910
-
(2009)
Mol Immunol
, vol.46
, pp. 978-990
-
-
Zhu, J.1
Brownlie, R.2
Liu, Q.3
Babiuk, L.A.4
Potter, A.5
Mutwiri, G.K.6
-
98
-
-
59249086205
-
Multiple molecular regions confer intracellular localization of bovine Toll-like receptor 8
-
1:CAS:528:DC%2BD1MXhsFersbw%3D 10.1016/j.molimm.2008.09.020 19019441
-
J Zhu S van Drunen Littel-van den Hurk R Brownlie LA Babiuk A Potter GK Mutwiri 2009 Multiple molecular regions confer intracellular localization of bovine Toll-like receptor 8 Mol Immunol 46 884 892 1:CAS:528: DC%2BD1MXhsFersbw%3D 10.1016/j.molimm.2008.09.020 19019441
-
(2009)
Mol Immunol
, vol.46
, pp. 884-892
-
-
Zhu, J.1
Van Drunen Littel-Van Den Hurk, S.2
Brownlie, R.3
Babiuk, L.A.4
Potter, A.5
Mutwiri, G.K.6
|