Structure-Activity Relationship of Synthetic Toll-like Receptor 4 Agonists

Journal of Biological Chemistry

Volumn 279, Issue 6, 2004, Pages 4440-4449

  Stöver, Axel G ^a   Da Silva Correia, Jean ^b   Evans, Jay T ^a   Cluff, Christopher W ^a   Elliott, Mark W ^a   Jeffery, Eric W ^a   Johnson, David A ^a   Lacy, Michael J ^a   Baldridge, Jory R ^a   Probst, Peter ^a   Ulevitch, Richard J ^b   Persing, David H ^a,c   Hershberg, Robert M ^a,c,d  

^a GLAXOSMITHKLINE   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c INFECTIOUS DISEASE RESEARCH INSTITUTE   (United States)

^d Dendreon   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON; CELLS; LIPIDS; MOLECULAR STRUCTURE; PHOSPHATES; POLYSACCHARIDES;

CELL TRANSFECTANTS; CYTOKINES;

BIOCHEMISTRY;

CHEMOKINE; CYTOKINE; LIPID A; LIPOPOLYSACCHARIDE; SYNTHETIC PEPTIDE; TOLL LIKE RECEPTOR 4;

ACYLATION; ARTICLE; CELL PROTECTION; COMPLEX FORMATION; EMBRYO DEVELOPMENT; HUMAN; HUMAN CELL; IMMUNOMODULATION; LIPOGENESIS; MOLECULAR CLONING; MOLECULAR RECOGNITION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; TRANSCRIPTION REGULATION;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; CYTOKINES; GENE EXPRESSION PROFILING; HUMANS; LIPID A; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; MOLECULAR MIMICRY; MONOCYTES; RECEPTORS, CELL SURFACE; STRUCTURE-ACTIVITY RELATIONSHIP; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS; TRANS-ACTIVATION (GENETICS); TUMOR NECROSIS FACTOR-ALPHA;

EID: 2442499153     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M310760200     Document Type: Article

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