Co-stimulation with TLR7/8 and TLR9 agonists induce down-regulation of innate immune responses in sheep blood mononuclear and B cells

Developmental and Comparative Immunology

Volumn 34, Issue 5, 2010, Pages 572-578

  Booth, Jayaum S ^a   Buza, Joram J ^a   Potter, Andrew ^a   Babiuk, Lorne A ^b   Mutwiri, George K ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

B cells; CpG DNA; Mononuclear cells; Sheep; Toll like receptors

Indexed keywords

ALPHA INTERFERON; CPG OLIGODEOXYNUCLEOTIDE; GAMMA INTERFERON; IMIQUIMOD; IMMUNOGLOBULIN M; INTERLEUKIN 10; INTERLEUKIN 12; LIPOPOLYSACCHARIDE; OLIGORIBONUCLEOTIDE; POLYINOSINIC POLYCYTIDYLIC ACID; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9; AMINOQUINOLINE DERIVATIVE; ANTISENSE OLIGODEOXYNUCLEOTIDE; ANTISENSE OLIGONUCLEOTIDE; CYTOKINE; TOLL LIKE RECEPTOR;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; FEMALE; GENE EXPRESSION; IMMUNOREGULATION; INNATE IMMUNITY; LYMPHOCYTE PROLIFERATION; MALE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; SHEEP; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CELL PROLIFERATION; DRUG EFFECT; DRUG POTENTIATION; GENETICS; IMMUNOLOGY; METABOLISM; MONONUCLEAR CELL; PATHOLOGY; SIGNAL TRANSDUCTION;

OVIS ARIES;

AMINOQUINOLINES; ANIMALS; B-LYMPHOCYTES; CELL PROLIFERATION; CELLS, CULTURED; CYTOKINES; DOWN-REGULATION; IMMUNITY, INNATE; IMMUNOGLOBULIN M; LEUKOCYTES, MONONUCLEAR; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; OLIGORIBONUCLEOTIDES, ANTISENSE; RECEPTOR CROSS-TALK; SHEEP; TOLL-LIKE RECEPTORS;

EID: 77953398245     PISSN: 0145305X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dci.2009.12.018     Document Type: Article

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