Protection of neonatal broiler chicks against Salmonella typhimurium septicemia by DNA containing CpG motifs

Avian Diseases

Volumn 52, Issue 3, 2008, Pages 398-406

  Taghavi, Azita ^a   Allan, Brenda ^b   Mutwiri, George ^b   Van Kessel, Andrew ^c   Willson, Philip ^b   Babiuk, Lorne ^b   Potter, Andrew ^b   Gomis, Susantha ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

^c UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

CpG ODN; Innate immunity; Neonatal chickens; Salmonella typhimurium; Septicemia

Indexed keywords

DNA VACCINE; OLIGODEOXYRIBONUCLEOTIDE;

ANIMAL; ANIMAL DISEASE; ANIMAL SALMONELLOSIS; ARTICLE; BIRD DISEASE; CHICKEN; COMPARATIVE STUDY; GENETICS; IMMUNOLOGY; MICROBIOLOGY; NUCLEOTIDE SEQUENCE; SALMONELLA TYPHIMURIUM; SEPSIS; SURVIVAL;

ANIMALS; BASE SEQUENCE; CHICKENS; OLIGODEOXYRIBONUCLEOTIDES; POULTRY DISEASES; SALMONELLA INFECTIONS, ANIMAL; SALMONELLA TYPHIMURIUM; SEPSIS; SURVIVAL ANALYSIS; VACCINES, DNA;

AVES; BACTERIA (MICROORGANISMS); GALLUS GALLUS; PROTOZOA; SALMONELLA TYPHIMURIUM; SPONDIAS PURPUREA; VERTEBRATA;

EID: 54249084609     PISSN: 00052086     EISSN: None     Source Type: Journal    
DOI: 10.1637/8196-121907-Reg     Document Type: Article

References (44)

1. Ahmad-Nejad, P., H. Hacker, M. Rutz, S. Bauer, R. M. Vabulas, and H. Wagner. Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments. Eur. J. Immunol. 32:1958-1968. 2002.
2. Ashkar, A. A., and K. L. Rosenthal. Toll-like receptor 9, CpG DNA and innate immunity. Curr. Mol. Med. (Hilversum) 2:545-556. 2002.
3. Barnes, H. J., J. P. Vaillancourt, and W. B. Gross. Colibacillosis. In: Diseases of poultry, 11th ed. Y. M. Saif, ed. Blackwell, Ames, IA. pp. 631-676. 2004.
4. Barrow, P., M. B. Huggins, M. A. Lovell, and J. M. Simpson. Observations on the pathogenesis of experimental Salmonella typhimurium infection in chickens. Res. Vet. Sci. 42:194-199. 1987.
5. Barry, A. L. Clinical specimens for microbiologic examination. In: Infectious diseases: a guide to the understanding and management of infectious processes, 1st ed. P. D. Haeprich, ed. Harper and Row, New York. pp. 103-107. 1992.
6. Bauer, M., V. Redecke, J. W. Ellwart, B. Scherer, J. P. Kremer, H. Wagner, and G. B. Lipford. Bacterial CpG-DNA triggers activation and maturation of human CD11c-, CD123+ dendritic cells. J. Immunol. 166:5000-5007. 2001.
7. Beal, R. K., P. Wigley, C. Powers, S. D. Hulme, P. A. Barrow, and A. L. Smith. Age at primary infection with Salmonella enterica serovar Typhimurium in the chicken influence persistence of infection and subsequent immunity to re-challenge. Vet. Immunol. Immunopathol. 100:151-169. 2004.
8. Carter, G. R., and D. J. Wise. Enterobacteria II: salmonella and yersina. In: Essentials of veterinary bacteriology and mycology, 6th ed. G. R. Carter and J. R. Cole, Jr., eds. BlackWell, Ames, IA. pp. 137-139. 2003.
9. Datta, N., S. Mukherjee, L. Das, and P. K. Das. Targeting of immunostimulatory DNA cures experimental visceral leishmaniasis through nitric oxide up-regulation and T cell activation. Eur. J. Immunol. 33:1508-1511. 2003.
10. Davis, H. L., I. I. Suparto, R. R. Weeratna, Jumintarto, D. D. Iskandriati, S. S. Chamzah, A. A. Ma'ruf, C. C. Nente, D. D. Pawitri, A. M. Krieg, Heriyanto, W. Smits, and D. D. Sajuthi. CpG DNA overcomes hyporesponsiveness to hepatitis B vaccine in orangutans. Vaccine 18:1920-1924. 2000.
11. Deng, J. C., T. A. Moore, M. W. Newstead, X. Zeng, A. M. Krieg, and T. J. Standiford. CpG oligodeoxynucleotides stimulate protective innate immunity against pulmonary Klebsiella infection. J. Immunol. 173:5148-5155. 2004.
12. Gast, R., and C. Beard. Age-related changes in the persistence and pathogenicity of Salmonella typhimurium in chickens. Poult. Sci. 68:1454-1460. 1989.
13. Gomis, S., L. Babiuk, B. Allan, P. Willson, E. Waters, N. Ambrose, R. Hecker, and A. Potter. Protection of neonatal chicks against a lethal challenge of Escherichia coli using DNA containing cytosine-phosphodiesterguanine motifs. Avian Dis. 48:813-822. 2004.
14. Gomis, S., L. Babiuk, D. L. Godson, B. Allan, T. Thrush, H. Townsend, P. Willson, E. Waters, R. A. Hecker, and A. Potter. Protection of chickens against Escherichia coli infections by DNA containing CpG motifs. Infect. Immun. 71:857-863. 2003.
15. Gramzinski, R. A., D. L. Doolan, M. Sedegah, H. L. Davis, A. M. Krieg, and S. L. Hoffman. Interleukin-12- and gamma interferon-dependent protection against malaria conferred by CpG oligodeoxynucleotide in mice. Infect. Immun. 69:1643-1649. 2001.
16. Harandi, A. M., K. Eriksson, and J. Holmgren. A protective role of locally administered immunostimulatory CpG oligodeoxynucleotide in a mouse model of genital herpes infection. J. Virol. 77:953-962. 2003.
17. He, H., T. L. Crippen, M. B. Farnell, and M. H. Kogut. Identification of CpG oligodeoxynucleotide motifs that stimulate nitric oxide and cytokine production in avian macrophage and peripheral blood mononuclear cells. Dev. Comp. Immunol. 27:621-627. 2003.
18. He, H., and M. H. Kogut. CpG-ODN-induced nitric oxide production is mediated through clathrin-dependent endocytosis, endosomal maturation and activation of PKC, MEK1/2 and p38 MAPK, and NF-kappaB pathways in avian macrophage cells (HD11). Cell Signal 15:911-917. 2003.
19. He, H., V. K. Lowry, C. L. Swaggerty, P. J. Ferro, and M. H. Kogut. In vitro activation of chicken leukocytes and in vivo protection against Salmonella Enteritidis organ invasion and peritoneal Salmonella Enteritidis infection-induced mortality in neonatal chickens by immunostimulatory CpG oligodeoxynucleotide. FEMS Immunol. Med. Microbiol. 43:81-89. 2005.
20. Hemmi, H., O. Takeuchi, T. Kawai, T. Kaisho, S. Sato, H. Sanjo, M. Matsumoto, K. Hoshino, H. Wagner, K. Takeda, and S. Akira. A Toll-like receptor recognizes bacterial DNA. Nature 408:740-745. 2000.
21. Jorgensen, J. B., A. Johansen, B. Stenersen, and A. L. Sommer. CpG oligodeoxynucleotides and plasmid DNA stimulate Atlantic salmon (Salmo salar L.) leucocytes to produce supernatants with antiviral activity. Dev. Comp. Immunol. 25:313-321. 2001.
22. Kamstrup, S., D. Verthelyi, and D. M. Klinman. Response of porcine peripheral blood mononuclear cells to CpG-containing oligodeoxynucleotides. Vet. Microbiol. 78:353-362. 2001.
23. Klinman, D. M., J. Conover, and C. Coban. Repeated administration of synthetic oligodeoxynucleotides expressing CpG motifs provides long-term protection against bacterial infection. Infect. Immun. 67:5658-5663. 1999.
24. Klinman, D. M., A. K. Yi, S. L. Beaucage, J. Conover, and A. M. Krieg. CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete inteleukin 6, interleukin 12, and interferon gamma. Proc. Natl. Acad. Sci. USA 93:2879-2883. 1996.
25. Krieg, A. M. CpG motifs in bacterial DNA and their immune effects. Annu. Rev. Immunol. 20:709-760. 2002.
26. Krieg, A. M., L. Love-Homan, A. K. Yi, and J. T. Harty. CpG DNA induces sustained IL-12 expression in vivo and resistance to Listeria monocytogenes challenge. J. Immunol. 161:2428-2434. 1998.
27. Le Minor, L., M. Veron, and M. Popoff. The taxonomy of Salmonella. Ann. Microbiol. (Paris) 133:233-243. 1982.
28. Libby, S. J., T. A. Halsey, C. Altier, J. Potter, and C. L. Gyles. Salmonella. In: Pathogenesis of bacterial infections in animal, 3rd ed. C. L. Gyles, J. F. Prescott, J. Glennsonger, and C. O. Thoen, eds. Blackwell, Ames, IA. pp. 143-167. 2004.
29. Medzhitov, R., and C. A. Janeway, Jr. Decoding the pattern of self and nonself by the innate immune system. Science 296:298-300. 2002.
30. Mena, A., A. K. Nichani, Y. Popowych, D. L. Godson, D. Dent, H. G. Townsend, G. K. Mutwiri, R. Hecker, L. A. Babiuk, and P. Griebel. Innate immune responses induced by CpG oligodeoxyribonucleotide stimulation of ovine blood mononuclear cells. J. Immunol. 110:250-257. 2003.
31. Meng, Z., J. Shao, and L. Xiang. CpG oligodeoxynucleotides activâte grass carp (Ctenopharyngodon idellus) macrophages. Dev. Comp. Immunol. 27:313-321. 2003.
32. Mutwiri, G., R. Pontarollo, S. Babiuk, P. Griebel, S. van Drunen Littel-van den Hurk, A. Mena, C. Tsang, V. Alcon, A. Nichani, X. Ioannou, S. Gomis, H. Townsend, R. Hecker, A. Potter, and L. A. Babiuk. Biological activity of immunostimulatory CpG DNA motifs in domestic animals. Vet. Immunol. Immunopathol. 91:89-103. 2003.
33. Patel, B. A., S. Gomis, A. Dar, P. J. Willson, L. A. Babiuk, A. Potter, G. Mutwiri, and S. K. Tikoo. Oligodeoxynucleotides containing CpG motifs (CpG-ODN) predominantly induce Th1-type immune response in neonatal chicks. Dev. Comp. Immunol. 32:1041-1049. 2008.
34. Ricks, C. A., A. Avakian, T. Bryan, R. Gildersleeve, E. Haddad, R. Ilich, S. King, I. Murray, P. Phelps, R. Poston, C. Whitfill, and C. Williams. In ovo vaccination technology. Adv. Vet. Med. 41:495-515. 1999.
35. Sanchez-Campillo, M., A. Chicano, A. Torio, E. Martin-Orozco, P. Gamiz, T. Hernandez-Caselles, and P. Garcia-Penarrubia. Implication of CpG-ODN and reactive oxygen species in the inhibition of intracellular growth of Salmonella typhimurium in hepatocytes. Microbes Infect. 6:813-820. 2004.
36. Schlaepfer, E., A. Audige, B. von Beust, V. Manolova, M. Weber, H. Joller, M. F. Bachmann, T. M. Kundig, and R. F. Speck. CpG oligodeoxynucleotides block human immunodeficiency virus type 1 replication in human lymphoid tissue infected ex vivo. J. Virol. 78:12344-12354. 2004.
37. Vleugels, B., C. Ververken, and B. M. Goddeeris. Stimulatory effect of CpG sequences on humoral response in chickens. Poult. Sci. 81:1317-1321. 2002.
38. Weeratna, R. D., M. J. McCluskie, Y. Xu, and H. L. Davis. CpG DNA induces stronger immune responses with less toxicity than other adjuvants. Vaccine 18:1755-1762. 2000.
39. Withanage, G. S., P. Wigley, P. Kaiser, P. Mastroeni, H. Brooks, C. Powers, R. Beal, P. Barrow, D. Maskell, and I. McConnell. Cytokine and chemokine responses associated with clearance of a primary Salmonella enterica serovar Typhimurium infection in the chicken and in protective immunity to rechallenge. Infect. Immun. 73:5173-5182. 2005.
40. Wongratanacheewin, S., W. Kespichayawattana, P. Intachote, S. Pichyangkul, R. W. Sermswan, A. M. Krieg, and S. Sirisinha. Immunostimulatory CpG oligodeoxynucleotide confers protection in a murine model of infection with Burkholderia pseudomallei. Infect. Immun. 72:4494-4502. 2004.
41. Yamamoto, S., T. Yamamoto, S. Shimada, E. Kuramoto, O. Yano, T. Kataoka, and T. Tokunaga. DNA from bacteria, but not from vertebrates, induces interferons, activates natural killer cells, and inhibits tumor growth. Microbiol. Immunol. 36:983-987. 1992.
42. Zecha, B. C., R. H. McCapes, W. M. Dungan, R. J. Holte, W. W. Worcester, and J. E. Williams. The Dillon Beach Project - a five-year epidemiological study of naturally occurring salmonella infection in turkeys and their environment. Avian Dis. 21:141-159. 1977.
43. Zhang, Y., L. K. Shoda, K. A. Brayton, D. M. Estes, G. H. Palmer, and W. C. Brown. Induction of interleukin-6 and interleukin-12 in bovine B lymphocytes, monocytes, and macrophages by a CpG oligodeoxynucleotide (ODN 2059) containing the GTCGTT motif. J. Interferon Cytokine Res. 21:871-881. 2001.
44. Zimmermann, S., O. Egeter, S. Hausmann, G. B. Lipford, M. Rocken, H. Wagner, and K. Heeg. CpG oligonucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis. J. Immunol. 160:3627-3630. 1998.