Toll-like receptor 2 antagonists. Part 1: Preliminary SAR investigation of novel synthetic phospholipids

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 24, 2005, Pages 5494-5498

  Spyvee, Mark R ^a   Zhang, Huiming ^a   Hawkins, Lynn D ^a   Chow, Jesse C ^a  

^a EISAI RESEARCH INSTITUTE   (United States)

Author keywords

Synthetic phospholipid; TLR2; TLR2 antagonist; Toll like receptor

Indexed keywords

PHOSPHOLIPID DERIVATIVE; RECEPTOR BLOCKING AGENT; TOLL LIKE RECEPTOR 2 ANTAGONIST; UNCLASSIFIED DRUG;

ARTICLE; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

HUMANS; INDICATORS AND REAGENTS; KINETICS; MODELS, MOLECULAR; PHOSPHOLIPIDS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TOLL-LIKE RECEPTOR 2;

EID: 27644533352     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.08.080     Document Type: Article

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