메뉴 건너뛰기




Volumn , Issue , 2006, Pages 357,XII-367,XII

Systemic Lupus Erythematosus: Immunologic Features

Author keywords

[No Author keywords available]

Indexed keywords


EID: 78651414541     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012595961-2/50031-7     Document Type: Chapter
Times cited : (6)

References (164)
  • 1
    • 0036318851 scopus 로고    scopus 로고
    • Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments
    • P. Ahmad-Nejad, H. Hacker, M. Rutz, S. Bauer, R.M. Vabulas and H. Wagner (2002) Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments. Eur. J. Immunol. 32 1958-1968.
    • (2002) Eur. J. Immunol. , vol.32 , pp. 1958-1968
    • Ahmad-Nejad, P.1    Hacker, H.2    Rutz, M.3    Bauer, S.4    Vabulas, R.M.5    Wagner, H.6
  • 2
    • 0023260343 scopus 로고
    • Mechanisms of T and B cell collaboration in the in vitro production of anti-DNA antibodies in the NZB/NZW F1 murine SLE model. The
    • D.G. Ando, E.E. Sercarz and B.H. Hahn (1987) Mechanisms of T and B cell collaboration in the in vitro production of anti-DNA antibodies in the NZB/NZW F1 murine SLE model. The. J. Immunol. 138 3185-3190.
    • (1987) J. Immunol. , vol.138 , pp. 3185-3190
    • Ando, D.G.1    Sercarz, E.E.2    Hahn, B.H.3
  • 3
    • 0035881627 scopus 로고    scopus 로고
    • Increased frequency of pre-germinal center B cells and plasma cell precursors in the blood of children with systemic lupus erythematosus
    • E. Arce, D.G. Jackson, M.A. Gill, L.B. Bennett, J. Banchereau and V. Pascual (2001) Increased frequency of pre-germinal center B cells and plasma cell precursors in the blood of children with systemic lupus erythematosus. J. Immunol. 167 2361-2369.
    • (2001) J. Immunol. , vol.167 , pp. 2361-2369
    • Arce, E.1    Jackson, D.G.2    Gill, M.A.3    Bennett, L.B.4    Banchereau, J.5    Pascual, V.6
  • 5
    • 7044269643 scopus 로고    scopus 로고
    • The emerging role of interferon in human systemic lupus erythematosus
    • E.C. Baechler, P.K. Gregersen and T.W. Behrens (2004) The emerging role of interferon in human systemic lupus erythematosus. Curr. Opin. Immunol. 16 801-807.
    • (2004) Curr. Opin. Immunol. , vol.16 , pp. 801-807
    • Baechler, E.C.1    Gregersen, P.K.2    Behrens, T.W.3
  • 6
    • 0025326912 scopus 로고
    • Immunogenic DNA-related factors. Nucleosomes spontaneously released from normal murine lymphoid cells stimulate proliferation and immunoglobulin synthesis of normal mouse lymphocytes
    • D.A. Bell, B. Morrison and P. VandenBygaart (1990) Immunogenic DNA-related factors. Nucleosomes spontaneously released from normal murine lymphoid cells stimulate proliferation and immunoglobulin synthesis of normal mouse lymphocytes. J. Clin. Invest. 85 1487-1496.
    • (1990) J. Clin. Invest. , vol.85 , pp. 1487-1496
    • Bell, D.A.1    Morrison, B.2    VandenBygaart, P.3
  • 8
    • 0028952442 scopus 로고
    • Glomerular binding activity in MRL Ipr serum consists of antibodies that bind to a DNA/histone/type IV collagen complex
    • K.A. Bernstein, R.D. Valerio and J.B. Lefkowith (1995) Glomerular binding activity in MRL Ipr serum consists of antibodies that bind to a DNA/histone/type IV collagen complex. J. Immunol. 154 2424-2433.
    • (1995) J. Immunol. , vol.154 , pp. 2424-2433
    • Bernstein, K.A.1    Valerio, R.D.2    Lefkowith, J.B.3
  • 9
    • 0018887198 scopus 로고
    • Increased immunoglobulin-secreting cells in the blood of patients with active systemic lupus erythematosus
    • R.M. Blaese, J. Grayson and A.D. Steinberg (1980) Increased immunoglobulin-secreting cells in the blood of patients with active systemic lupus erythematosus. Am. J. Med. 69 345-350.
    • (1980) Am. J. Med. , vol.69 , pp. 345-350
    • Blaese, R.M.1    Grayson, J.2    Steinberg, A.D.3
  • 10
    • 0035900481 scopus 로고    scopus 로고
    • Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus
    • P. Blanco, A.K. Palucka, M. Gill, V. Pascual and J. Banchereau (2001) Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus. Science 294 1540-1543.
    • (2001) Science , vol.294 , pp. 1540-1543
    • Blanco, P.1    Palucka, A.K.2    Gill, M.3    Pascual, V.4    Banchereau, J.5
  • 11
    • 0033695963 scopus 로고    scopus 로고
    • Spontaneous autoimmune disease in Fe(gamma)RIIB-deficient mice results from strain-specific epistasis
    • S. Bolland and J.V. Ravetch (2000) Spontaneous autoimmune disease in Fe(gamma)RIIB-deficient mice results from strain-specific epistasis. Immunity 13 277-285.
    • (2000) Immunity , vol.13 , pp. 277-285
    • Bolland, S.1    Ravetch, J.V.2
  • 12
    • 0037333857 scopus 로고    scopus 로고
    • A short course of BG9588 (anti-CD40 ligand antibody) improves serologic activity and decreases hematuria in patients with proliferative lupus glomerulonephritis
    • D.T. Boumpas, R. Furie, S. Manzi, G.G. Illei, D.J. Wallace, J.E. Balow and A. Vaishnaw (2003) A short course of BG9588 (anti-CD40 ligand antibody) improves serologic activity and decreases hematuria in patients with proliferative lupus glomerulonephritis. Arthritis Rheum. 48 719-727.
    • (2003) Arthritis Rheum. , vol.48 , pp. 719-727
    • Boumpas, D.T.1    Furie, R.2    Manzi, S.3    Illei, G.G.4    Wallace, D.J.5    Balow, J.E.6    Vaishnaw, A.7
  • 13
    • 0037438466 scopus 로고    scopus 로고
    • CD4+ T cells from lupusprone mice avoid antigen-specific tolerance induction in vivo
    • F. Bouzahzah, S. Jung and J. Craft (2003) CD4+ T cells from lupusprone mice avoid antigen-specific tolerance induction in vivo. J. Immunol. 170 741-748.
    • (2003) J. Immunol. , vol.170 , pp. 741-748
    • Bouzahzah, F.1    Jung, S.2    Craft, J.3
  • 15
    • 0347986780 scopus 로고    scopus 로고
    • Activation of diverse repertoires of autoreactive T cells enhances the loss of anti-dsDNA B cell tolerance
    • B.W. Busser, B.S. Adair, J. Erikson and T.M. Laufer (2003) Activation of diverse repertoires of autoreactive T cells enhances the loss of anti-dsDNA B cell tolerance. J. Clin. Invest. 112 1361-1371.
    • (2003) J. Clin. Invest. , vol.112 , pp. 1361-1371
    • Busser, B.W.1    Adair, B.S.2    Erikson, J.3    Laufer, T.M.4
  • 16
    • 0031882091 scopus 로고    scopus 로고
    • A new role for B cells in systemic autoimmunity: B cells promote spontaneous T cell activation in MRL-lpr/lpr mice
    • O. Chan and M.J. Shlomchik (1998) A new role for B cells in systemic autoimmunity: B cells promote spontaneous T cell activation in MRL-lpr/lpr mice. J. Immunol. 160 51-59.
    • (1998) J. Immunol. , vol.160 , pp. 51-59
    • Chan, O.1    Shlomchik, M.J.2
  • 17
    • 0033577903 scopus 로고    scopus 로고
    • A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus
    • O.T. Chan, L.G. Hannum, A.M. Haberman, M.P. Madaio and M.J. Shlomchik (1999) A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus. J. Exp. Med. 189 1639-1648.
    • (1999) J. Exp. Med. , vol.189 , pp. 1639-1648
    • Chan, O.T.1    Hannum, L.G.2    Haberman, A.M.3    Madaio, M.P.4    Shlomchik, M.J.5
  • 18
    • 0018773148 scopus 로고
    • Selective depression of the xenogeneic cell-mediated lympholysis in systemic lupus erythematosus
    • B. Charpentier, C. Carnaud and J.F. Bach (1979) Selective depression of the xenogeneic cell-mediated lympholysis in systemic lupus erythematosus. J. Clin. Invest. 64 351-360.
    • (1979) J. Clin. Invest. , vol.64 , pp. 351-360
    • Charpentier, B.1    Carnaud, C.2    Bach, J.F.3
  • 19
    • 0032512855 scopus 로고    scopus 로고
    • Uncoupling of immune complex formation and kidney damage in autoimmune glomerulonephritis
    • R. Clynes, C. Dumitru and J.V. Ravetch (1998) Uncoupling of immune complex formation and kidney damage in autoimmune glomerulonephritis. Science 279 1052-1054.
    • (1998) Science , vol.279 , pp. 1052-1054
    • Clynes, R.1    Dumitru, C.2    Ravetch, J.V.3
  • 20
    • 8544265317 scopus 로고    scopus 로고
    • Forkhead-box transcription factors and their role in the immune system
    • P.J. Coffer and B.M. Burgering (2004) Forkhead-box transcription factors and their role in the immune system. Nat. Rev. Immunol. 4 889-899.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 889-899
    • Coffer, P.J.1    Burgering, B.M.2
  • 21
    • 0032797012 scopus 로고    scopus 로고
    • Autoreactive T cells in murine lupus: Origins and roles in autoantibody production
    • J. Craft, S. Peng, T. Fujii, M. Okada and S. Fatenejad (1999) Autoreactive T cells in murine lupus: Origins and roles in autoantibody production. Immunol. Res. 19 245-257.
    • (1999) Immunol. Res. , vol.19 , pp. 245-257
    • Craft, J.1    Peng, S.2    Fujii, T.3    Okada, M.4    Fatenejad, S.5
  • 22
    • 0028229905 scopus 로고
    • Autoantigen-specific T cell proliferation induced by the ribosomal P2 protein in patients with systemic lupus erythematosus
    • M.K. Crow, G. DelGiudice-Asch, J.B. Zehetbauer, J.L. Lawson, N. Brot, H. Weissbach and K.B. Elkon (1994) Autoantigen-specific T cell proliferation induced by the ribosomal P2 protein in patients with systemic lupus erythematosus. J. Clin. Invest. 94 345-352.
    • (1994) J. Clin. Invest. , vol.94 , pp. 345-352
    • Crow, M.K.1    DelGiudice-Asch, G.2    Zehetbauer, J.B.3    Lawson, J.L.4    Brot, N.5    Weissbach, H.6    Elkon, K.B.7
  • 23
    • 0034810412 scopus 로고    scopus 로고
    • Regulation of CD40 ligand expression in systemic lupus erythematosus
    • M.K. Crow and K.A. Kirou (2001) Regulation of CD40 ligand expression in systemic lupus erythematosus. Curr. Opin. Rheumatol. 13 361-369.
    • (2001) Curr. Opin. Rheumatol. , vol.13 , pp. 361-369
    • Crow, M.K.1    Kirou, K.A.2
  • 24
    • 4344617762 scopus 로고    scopus 로고
    • Interferon-alpha in systemic lupus erythematosus
    • M.K. Crow and K.A. Kirou (2004) Interferon-alpha in systemic lupus erythematosus. Curr. Opin. Rheumatol. 16 541-547.
    • (2004) Curr. Opin. Rheumatol. , vol.16 , pp. 541-547
    • Crow, M.K.1    Kirou, K.A.2
  • 25
    • 0034532208 scopus 로고    scopus 로고
    • Increased interferon-gamma (IFN-gamma). IL-10 and decreased IL-4 mRNA expression in peripheral blood mononuclear cells (PBMC) from patients with systemic lupus erythematosus (SLE)
    • A. Csiszar, G. Nagy, P. Gergely, T. Pozsonyi T> and E. Pocsik (2000) Increased interferon-gamma (IFN-gamma). IL-10 and decreased IL-4 mRNA expression in peripheral blood mononuclear cells (PBMC) from patients with systemic lupus erythematosus (SLE). Clin. Exp. Immunol. 122 464-470.
    • (2000) Clin. Exp. Immunol. , vol.122 , pp. 464-470
    • Csiszar, A.1    Nagy, G.2    Gergely, P.3    Pozsonyi, T.4    Pocsik, E.5
  • 26
    • 0031253956 scopus 로고    scopus 로고
    • Long-term inhibition of murine lupus by brief simultaneous blockade of the B7/CD28 and CD40/gp39 costimulation pathways
    • D.I. Daikh, B.K. Finck, P.S. Linsley, D. Hollenbaugh and D. Wofsy (1997) Long-term inhibition of murine lupus by brief simultaneous blockade of the B7/CD28 and CD40/gp39 costimulation pathways. J. Immunol. 159 3104-3108.
    • (1997) J. Immunol. , vol.159 , pp. 3104-3108
    • Daikh, D.I.1    Finck, B.K.2    Linsley, P.S.3    Hollenbaugh, D.4    Wofsy, D.5
  • 27
    • 0037387403 scopus 로고    scopus 로고
    • Dendritic cell responses to early murine cytomegalovirus infection: subset functional specialization and differential regulation by interferon alpha/beta
    • M. Dalod, T. Hamilton, R. Salomon, T.P. Salazar-Mather, S.C. Henry, J.D. Hamilton and C.A. Biron (2003) Dendritic cell responses to early murine cytomegalovirus infection: subset functional specialization and differential regulation by interferon alpha/beta. J. Exp. Med. 197 885-898.
    • (2003) J. Exp. Med. , vol.197 , pp. 885-898
    • Dalod, M.1    Hamilton, T.2    Salomon, R.3    Salazar-Mather, T.P.4    Henry, S.C.5    Hamilton, J.D.6    Biron, C.A.7
  • 28
    • 0021342845 scopus 로고
    • The in vivo and in vitro glomerular deposition of isolated anti-double-stranded-DNA antibodies in NZB/W mice
    • H. Dang and R.J. Harbeck (1984) The in vivo and in vitro glomerular deposition of isolated anti-double-stranded-DNA antibodies in NZB/W mice. Clin. Immunol. Immunopathol. 30 265-278.
    • (1984) Clin. Immunol. Immunopathol. , vol.30 , pp. 265-278
    • Dang, H.1    Harbeck, R.J.2
  • 29
    • 0025325145 scopus 로고
    • Molecular characterization of a somatically mutated anti-DNA antibody bearing two SLE related idiotypes
    • A. Davidson, A. Mannheimer-Lory, C. Aranow, R. Peterson, N. Hannigan and B. Diamond (1990) Molecular characterization of a somatically mutated anti-DNA antibody bearing two SLE related idiotypes. J. Clin. Invest. 85 1401-1409.
    • (1990) J. Clin. Invest. , vol.85 , pp. 1401-1409
    • Davidson, A.1    Mannheimer-Lory, A.2    Aranow, C.3    Peterson, R.4    Hannigan, N.5    Diamond, B.6
  • 30
    • 0035173156 scopus 로고    scopus 로고
    • A subset of lupus anti-DNA antibodies crossreacts with the NR2 glutamate receptor in systemic lupus erythematosus
    • L.A. DeGiorgio, K.N. Konstantinov, S.C. Lee, J.A. Hardin, B.T. Volpe and B. Diamond (2001) A subset of lupus anti-DNA antibodies crossreacts with the NR2 glutamate receptor in systemic lupus erythematosus. Nat. Med. 7 1189-1193.
    • (2001) Nat. Med. , vol.7 , pp. 1189-1193
    • DeGiorgio, L.A.1    Konstantinov, K.N.2    Lee, S.C.3    Hardin, J.A.4    Volpe, B.T.5    Diamond, B.6
  • 31
    • 0003141917 scopus 로고
    • The precipitin reaction between DNA and a serum factor in SLE
    • H.R. Deicher, H.R. Holman and H.G. Kunkel (1959) The precipitin reaction between DNA and a serum factor in SLE. J. Exp. Med. 109 97.
    • (1959) J. Exp. Med. , vol.109 , pp. 97
    • Deicher, H.R.1    Holman, H.R.2    Kunkel, H.G.3
  • 32
    • 0037087262 scopus 로고    scopus 로고
    • Alphaactinin is a cross-reactive renal target for pathogenic anti-DNA antibodies
    • B. Deocharan, X. Qing, J. Lichauco and C. Putterman (2002) Alphaactinin is a cross-reactive renal target for pathogenic anti-DNA antibodies. J. Immunol. 168 3072-3078.
    • (2002) J. Immunol. , vol.168 , pp. 3072-3078
    • Deocharan, B.1    Qing, X.2    Lichauco, J.3    Putterman, C.4
  • 33
    • 0029913381 scopus 로고    scopus 로고
    • Hyperexpression of CD40 ligand by B and T cells in human lupus and its role in pathogenic autoantibody production
    • A. Desai-Mehta, L. Lu, R. Ramsey-Goldman and S.K. Datta (1996) Hyperexpression of CD40 ligand by B and T cells in human lupus and its role in pathogenic autoantibody production. J. Clin. Invest. 97 2063-2073.
    • (1996) J. Clin. Invest. , vol.97 , pp. 2063-2073
    • Desai-Mehta, A.1    Lu, L.2    Ramsey-Goldman, R.3    Datta, S.K.4
  • 34
    • 0028798616 scopus 로고
    • Structure and specificity of T cell receptors expressed by potentially pathogenic anti-DNA autoantibody-inducing T cells in human lupus
    • A. Desai-Mehta, C. Mao, S. Rajagopalan, T. Robinson and S.K. Datta (1995) Structure and specificity of T cell receptors expressed by potentially pathogenic anti-DNA autoantibody-inducing T cells in human lupus. J. Clin. Invest. 95 531-541.
    • (1995) J. Clin. Invest. , vol.95 , pp. 531-541
    • Desai-Mehta, A.1    Mao, C.2    Rajagopalan, S.3    Robinson, T.4    Datta, S.K.5
  • 35
    • 0029122854 scopus 로고
    • Murine lupus glomerulotropic monoclonal antibodies exhibit differing specificities but bind via a common mechanism
    • R. Di Valerio, K.A. Bernstein, E. Varghese and J.B. Lefkowith (1995) Murine lupus glomerulotropic monoclonal antibodies exhibit differing specificities but bind via a common mechanism. J. Immunol. 155 2258-2268.
    • (1995) J. Immunol. , vol.155 , pp. 2258-2268
    • Di Valerio, R.1    Bernstein, K.A.2    Varghese, E.3    Lefkowith, J.B.4
  • 36
    • 1542317550 scopus 로고    scopus 로고
    • Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
    • S.S. Diebold, T. Kaisho, H. Hemmi, S. Akira and C. Reis e Sousa (2004) Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 303 1529-1531.
    • (2004) Science , vol.303 , pp. 1529-1531
    • Diebold, S.S.1    Kaisho, T.2    Hemmi, H.3    Akira, S.4    Reis e Sousa, C.5
  • 37
    • 0035424309 scopus 로고    scopus 로고
    • Post-translational protein modifications in antigen recognition and autoimmunity
    • H.A. Doyle and M.J. Mamula (2001) Post-translational protein modifications in antigen recognition and autoimmunity. Trends Immunol. 22 443-449.
    • (2001) Trends Immunol. , vol.22 , pp. 443-449
    • Doyle, H.A.1    Mamula, M.J.2
  • 38
    • 0030267659 scopus 로고    scopus 로고
    • Anti-CD40 ligand antibody treatment prevents the development of lupus-like nephritis in a subset of New Zealand black × New Zealand white mice. Response correlates with the absence of an anti-antibody response
    • G.S. Early, W. Zhao and C.M. Burns (1996) Anti-CD40 ligand antibody treatment prevents the development of lupus-like nephritis in a subset of New Zealand black × New Zealand white mice. Response correlates with the absence of an anti-antibody response. J. Immunol. 157 3159-3164.
    • (1996) J. Immunol. , vol.157 , pp. 3159-3164
    • Early, G.S.1    Zhao, W.2    Burns, C.M.3
  • 39
    • 0027971945 scopus 로고
    • Apoptosis in SLE: too little or too much?
    • K.B. Elkon (1994) Apoptosis in SLE: too little or too much? Clin. Exp. Rheumatol. 12 553.
    • (1994) Clin. Exp. Rheumatol. , vol.12 , pp. 553
    • Elkon, K.B.1
  • 41
    • 0020073596 scopus 로고
    • Clearance of circulating DNA-anti-DNA immune complexes in mice
    • W. Emlen and M. Mannik (1982) Clearance of circulating DNA-anti-DNA immune complexes in mice. J. Exp. Med. 155 1210-1215.
    • (1982) J. Exp. Med. , vol.155 , pp. 1210-1215
    • Emlen, W.1    Mannik, M.2
  • 42
    • 0028330345 scopus 로고
    • Accelerated in vitro apoptosis of lymphocytes from patients with systemic lupus erythematosus
    • W. Emlen, J. Niebur and R. Kadera (1994) Accelerated in vitro apoptosis of lymphocytes from patients with systemic lupus erythematosus. J. Immunol. 152 3685-3692.
    • (1994) J. Immunol. , vol.152 , pp. 3685-3692
    • Emlen, W.1    Niebur, J.2    Kadera, R.3
  • 43
    • 0034744286 scopus 로고    scopus 로고
    • Fc epsilon receptor type 1 gamma chain replaces the deficient T cell receptor zeta chain in T cells of patients with systemic lupus erythematosus
    • E.J. Enyedy, M.P. Nambiar, S.N. Liossis, G. Dennis, G.M. Kammer and G.C. Tsokos (2001) Fc epsilon receptor type 1 gamma chain replaces the deficient T cell receptor zeta chain in T cells of patients with systemic lupus erythematosus. Arthritis Rheum. 44 1114-1121.
    • (2001) Arthritis Rheum. , vol.44 , pp. 1114-1121
    • Enyedy, E.J.1    Nambiar, M.P.2    Liossis, S.N.3    Dennis, G.4    Kammer, G.M.5    Tsokos, G.C.6
  • 44
    • 0022544539 scopus 로고
    • Cross-reactivity of human and murine anti-DNA antibodies with heparan sulfate. The major glycosaminoglycan in glomerular basement membranes
    • P. Faaber, T.P. Rijke, L.B. van de Putte, P.J. Capel and J.H. Berden (1986) Cross-reactivity of human and murine anti-DNA antibodies with heparan sulfate. The major glycosaminoglycan in glomerular basement membranes. J. Clin. Invest. 77 1824-1830.
    • (1986) J. Clin. Invest. , vol.77 , pp. 1824-1830
    • Faaber, P.1    Rijke, T.P.2    van de Putte, L.B.3    Capel, P.J.4    Berden, J.H.5
  • 45
    • 0032402260 scopus 로고    scopus 로고
    • Central T cell tolerance in lupus-prone mice: influence of autoimmune background and the Ipr mutation
    • S. Fatenejad, S.L. Peng, O. Disorbo and J. Craft (1998) Central T cell tolerance in lupus-prone mice: influence of autoimmune background and the Ipr mutation. J. Immunol. 161 6427-6432.
    • (1998) J. Immunol. , vol.161 , pp. 6427-6432
    • Fatenejad, S.1    Peng, S.L.2    Disorbo, O.3    Craft, J.4
  • 46
    • 0028483990 scopus 로고
    • Treatment of murine lupus with CTLA4Ig
    • B.K. Finck, P.S. Linsley and D. Wofsy (1994) Treatment of murine lupus with CTLA4Ig. Science 265 1225-1227.
    • (1994) Science , vol.265 , pp. 1225-1227
    • Finck, B.K.1    Linsley, P.S.2    Wofsy, D.3
  • 47
    • 0001153443 scopus 로고
    • Clinical application of lupus serum; nucleoprotein reaction using fluorescent antibody technique
    • G.J. Friou (1957) Clinical application of lupus serum; nucleoprotein reaction using fluorescent antibody technique. J. Clin. Invest. 36 890.
    • (1957) J. Clin. Invest. , vol.36 , pp. 890
    • Friou, G.J.1
  • 48
    • 12344273445 scopus 로고    scopus 로고
    • The inhibitory Fegamma receptor modulates autoimmunity by limiting the accumulation of immunoglobulin G+ anti-DNA plasma cells
    • H. Fukuyama, F. Nimmerjahn and J.V. Ravetch (2005) The inhibitory Fegamma receptor modulates autoimmunity by limiting the accumulation of immunoglobulin G+ anti-DNA plasma cells. Nat. Immunol. 6 99-106.
    • (2005) Nat. Immunol. , vol.6 , pp. 99-106
    • Fukuyama, H.1    Nimmerjahn, F.2    Ravetch, J.V.3
  • 49
    • 3242656232 scopus 로고    scopus 로고
    • Glomerular binding antibodies in systemic lupus erythematosus
    • G.M. Kammer, G.C. Tsokos (Eds), Totowa, N.J.: Humana Press
    • G.S. Gilkeson (1999) Glomerular binding antibodies in systemic lupus erythematosus. G.M. Kammer, G.C. Tsokos (Eds) Lupus: Molecular and Cellular Pathogenesis Totowa, N.J.: Humana Press
    • (1999) Lupus: Molecular and Cellular Pathogenesis
    • Gilkeson, G.S.1
  • 50
    • 0345824714 scopus 로고    scopus 로고
    • Abnormal germinal center reactions in systemic lupus erythematosus demonstrated by blockade of CD154-CD40 interactions
    • A.C. Grammer, R. Slota, R. Fischer, H. Gur, H. Girschick, C. Yarboro, G.G. Illei and P.E. Lipsky (2003) Abnormal germinal center reactions in systemic lupus erythematosus demonstrated by blockade of CD154-CD40 interactions. J. Clin. Invest. 112 1506-1520.
    • (2003) J. Clin. Invest. , vol.112 , pp. 1506-1520
    • Grammer, A.C.1    Slota, R.2    Fischer, R.3    Gur, H.4    Girschick, H.5    Yarboro, C.6    Illei, G.G.7    Lipsky, P.E.8
  • 54
    • 0032529411 scopus 로고    scopus 로고
    • IFN-alpha priming of human monocytes differentially regulates gram-positive and gram-negative bacteria-induced IL-10 release and selectively enhances IL-12p70, CD80, and MHC class I expression
    • P. Hermann, M. Rubio, T. Nakajima, G. Delespesse and M. Sarfati (1998) IFN-alpha priming of human monocytes differentially regulates gram-positive and gram-negative bacteria-induced IL-10 release and selectively enhances IL-12p70, CD80, and MHC class I expression. J. Immunol. 161 2011-2018.
    • (1998) J. Immunol. , vol.161 , pp. 2011-2018
    • Hermann, P.1    Rubio, M.2    Nakajima, T.3    Delespesse, G.4    Sarfati, M.5
  • 55
    • 6044259760 scopus 로고    scopus 로고
    • T cells in the pathogenesis of systemic lupus erythematosus
    • R.W. Hoffman (2004) T cells in the pathogenesis of systemic lupus erythematosus. Clin. Immunol. 113 4-13.
    • (2004) Clin. Immunol. , vol.113 , pp. 4-13
    • Hoffman, R.W.1
  • 56
    • 0027433523 scopus 로고
    • Human T cell clones reactive against U-small nuclear ribonucleoprotein autoantigens from connective tissue disease patients and healthy individuals
    • R.W. Hoffman, Y. Takeda, G.C. Sharp, D.R. Lee, D.L. Hill, H. Kaneoka and C.W. Caldwell (1993) Human T cell clones reactive against U-small nuclear ribonucleoprotein autoantigens from connective tissue disease patients and healthy individuals. J. Immunol. 151 6460-6469.
    • (1993) J. Immunol. , vol.151 , pp. 6460-6469
    • Hoffman, R.W.1    Takeda, Y.2    Sharp, G.C.3    Lee, D.R.4    Hill, D.L.5    Kaneoka, H.6    Caldwell, C.W.7
  • 57
    • 0000137417 scopus 로고
    • Affinity between the lupus erythematosus serum factor and cell nuclei and nucleoprotein
    • H.R. Holman and H.G. Kunkel (1957) Affinity between the lupus erythematosus serum factor and cell nuclei and nucleoprotein. Science 126 162.
    • (1957) Science , vol.126 , pp. 162
    • Holman, H.R.1    Kunkel, H.G.2
  • 61
    • 0032145230 scopus 로고    scopus 로고
    • A subset of CD4+ T cells expressing early activation antigen CD69 in murine lupus: possible abnormal regulatory role for cytokine imbalance
    • S. Ishikawa, S. Akakura, M. Abe, K. Terashima, K. Chijiiwa, H. Nishimura, S. Hirose and T. Shirai (1998) A subset of CD4+ T cells expressing early activation antigen CD69 in murine lupus: possible abnormal regulatory role for cytokine imbalance. J. Immunol. 161 1267-1273.
    • (1998) J. Immunol. , vol.161 , pp. 1267-1273
    • Ishikawa, S.1    Akakura, S.2    Abe, M.3    Terashima, K.4    Chijiiwa, K.5    Nishimura, H.6    Hirose, S.7    Shirai, T.8
  • 62
    • 5444262511 scopus 로고    scopus 로고
    • Toll-like receptor control of the adaptive immune responses
    • A. Iwasaki and R. Medzhitov (2004) Toll-like receptor control of the adaptive immune responses. Nat. Immunol. 5 987-995.
    • (2004) Nat. Immunol. , vol.5 , pp. 987-995
    • Iwasaki, A.1    Medzhitov, R.2
  • 63
    • 0017084411 scopus 로고
    • In vitro demonstration of a particular affinity of glomerular basement membrane and collagen for DNA. A possible basis for a local formation of DNA-anti-DNA complexes in systemic lupus erythematosus
    • S. Izui, P.H. Lambert and P.A. Miescher (1976) In vitro demonstration of a particular affinity of glomerular basement membrane and collagen for DNA. A possible basis for a local formation of DNA-anti-DNA complexes in systemic lupus erythematosus. J. Exp. Med. 144 428-443.
    • (1976) J. Exp. Med. , vol.144 , pp. 428-443
    • Izui, S.1    Lambert, P.H.2    Miescher, P.A.3
  • 64
    • 0017592950 scopus 로고
    • Failure to detect circulating DNA-anti-DNA complexes by four radioimmunological methods in patients with systemic lupus erythematosus
    • S. Izui, P.H. Lambert and P.A. Miescher (1977) Failure to detect circulating DNA-anti-DNA complexes by four radioimmunological methods in patients with systemic lupus erythematosus. Clin. Exp. Immunol. 30 384-392.
    • (1977) Clin. Exp. Immunol. , vol.30 , pp. 384-392
    • Izui, S.1    Lambert, P.H.2    Miescher, P.A.3
  • 65
    • 0022001632 scopus 로고
    • Binding of a monoclonal anti-DNA autoantibody to identical protein(s) present at the surface of several human cell types involved in lupus pathogenesis
    • L. Jacob, M.A. Lety, D. Louvard and J.F. Bach (1985) Binding of a monoclonal anti-DNA autoantibody to identical protein(s) present at the surface of several human cell types involved in lupus pathogenesis. J. Clin. Invest. 75 315-317.
    • (1985) J. Clin. Invest. , vol.75 , pp. 315-317
    • Jacob, L.1    Lety, M.A.2    Louvard, D.3    Bach, J.F.4
  • 67
    • 0028326095 scopus 로고
    • Prevention of nephritis in major histocompatibility complex class II-deficient MRL-lpr mice
    • A.M. Jevnikar, M.J. Grusby and L.H. Glimcher (1994) Prevention of nephritis in major histocompatibility complex class II-deficient MRL-lpr mice. J. Exp. Med. 179 1137-1143.
    • (1994) J. Exp. Med. , vol.179 , pp. 1137-1143
    • Jevnikar, A.M.1    Grusby, M.J.2    Glimcher, L.H.3
  • 68
    • 0031573510 scopus 로고    scopus 로고
    • Resting B cells from autoimmune lupus-prone New Zealand Black and (New Zealand Black × New Zealand White)F1 mice are hyper-responsive to T cell-derived stimuli
    • J. Jongstra-Bilen, B. Vukusic, K. Boras and J.E. Wither (1997) Resting B cells from autoimmune lupus-prone New Zealand Black and (New Zealand Black × New Zealand White)F1 mice are hyper-responsive to T cell-derived stimuli. J. Immunol. 159 5810-5820.
    • (1997) J. Immunol. , vol.159 , pp. 5810-5820
    • Jongstra-Bilen, J.1    Vukusic, B.2    Boras, K.3    Wither, J.E.4
  • 69
    • 16844376445 scopus 로고    scopus 로고
    • Systemic lupus erythematosus serum IgG increases CREM binding to the IL-2 promoter and suppresses IL-2 production through CAMVIV
    • Y.T. Juang, Y. Wang, E.E. Solomou, Y. Li, C. Mawrin, K. Tenbrock, V. Kyttaris and G.C. Tsokos (2005) Systemic lupus erythematosus serum IgG increases CREM binding to the IL-2 promoter and suppresses IL-2 production through CAMVIV. J. Clin. Invest. 115 996-1005.
    • (2005) J. Clin. Invest. , vol.115 , pp. 996-1005
    • Juang, Y.T.1    Wang, Y.2    Solomou, E.E.3    Li, Y.4    Mawrin, C.5    Tenbrock, K.6    Kyttaris, V.7    Tsokos, G.C.8
  • 70
    • 2142710163 scopus 로고    scopus 로고
    • Altered lipid raft-associated signaling and ganglioside expression in T lymphocytes from patients with systemic lupus erythematosus
    • E.C. Jury, P.S. Kabouridis, F. Flores-Borja, R.A.I. Mageed and D.A. Isenberg (2004) Altered lipid raft-associated signaling and ganglioside expression in T lymphocytes from patients with systemic lupus erythematosus. J. Clin. Invest. 113 1176-1187.
    • (2004) J. Clin. Invest. , vol.113 , pp. 1176-1187
    • Jury, E.C.1    Kabouridis, P.S.2    Flores-Borja, F.3    Mageed, R.A.I.4    Isenberg, D.A.5
  • 71
    • 0029953857 scopus 로고    scopus 로고
    • Nucleosomal peptide epitopes for nephritis-inducing T helper cells of murine lupus
    • A. Kaliyaperumal, C. Mohan, W. Wu and S.K. Datta (1996) Nucleosomal peptide epitopes for nephritis-inducing T helper cells of murine lupus. J. Exp. Med. 183 2459-2469.
    • (1996) J. Exp. Med. , vol.183 , pp. 2459-2469
    • Kaliyaperumal, A.1    Mohan, C.2    Wu, W.3    Datta, S.K.4
  • 72
    • 0032030667 scopus 로고    scopus 로고
    • Anti-CD40 ligand antibody treatment of SNF1 mice with established nephritis: preservation of kidney function
    • S.L. Kalled, A.H. Cutler, S.K. Datta and D.W. Thomas (1998) Anti-CD40 ligand antibody treatment of SNF1 mice with established nephritis: preservation of kidney function. J. Immunol. 160 2158-2165.
    • (1998) J. Immunol. , vol.160 , pp. 2158-2165
    • Kalled, S.L.1    Cutler, A.H.2    Datta, S.K.3    Thomas, D.W.4
  • 73
    • 16844365147 scopus 로고    scopus 로고
    • Altered regulation of IL-2 production in systemic lupus erythematosus: an evolving paradigm
    • G.M. Kammer (2005) Altered regulation of IL-2 production in systemic lupus erythematosus: an evolving paradigm. J. Clin. Invest. 115 836-840.
    • (2005) J. Clin. Invest. , vol.115 , pp. 836-840
    • Kammer, G.M.1
  • 74
    • 0030587119 scopus 로고    scopus 로고
    • Deficient type I protein kinase A isozyme activity in systemic lupus erythematosus T lymphocytes: II. Abnormal isozyme kinetics
    • G.M. Kammer, I.U. Khan, J.A. Kammer, L. Olorenshaw and D. Mathis (1996) Deficient type I protein kinase A isozyme activity in systemic lupus erythematosus T lymphocytes: II. Abnormal isozyme kinetics. J. Immunol. 157 2690-2698.
    • (1996) J. Immunol. , vol.157 , pp. 2690-2698
    • Kammer, G.M.1    Khan, I.U.2    Kammer, J.A.3    Olorenshaw, L.4    Mathis, D.5
  • 75
    • 0036560022 scopus 로고    scopus 로고
    • Abnormal T cell signal transduction in systemic lupus erythematosus
    • G.M. Kammer, A. Perl, B.C. Richardson and G.C. Tsokos (2002) Abnormal T cell signal transduction in systemic lupus erythematosus. Arthritis Rheum. 46 1139-1154.
    • (2002) Arthritis Rheum. , vol.46 , pp. 1139-1154
    • Kammer, G.M.1    Perl, A.2    Richardson, B.C.3    Tsokos, G.C.4
  • 76
    • 1642495711 scopus 로고    scopus 로고
    • Defective control of latent Epstein-Barr virus infection in systemic lupus erythematosus
    • I. Kang, T. Quan, H. Nolasco, S.H. Park, M.S. Hong, J.G. Howe and J. Craft (2004) Defective control of latent Epstein-Barr virus infection in systemic lupus erythematosus. J. Immunol. 172 1287-1294.
    • (2004) J. Immunol. , vol.172 , pp. 1287-1294
    • Kang, I.1    Quan, T.2    Nolasco, H.3    Park, S.H.4    Hong, M.S.5    Howe, J.G.6    Craft, J.7
  • 78
    • 0014135030 scopus 로고
    • Immunological studies concerning the nephritis of systemic lupus erythematosus
    • D. Koffler, P.H. Schur and H.G. Kunkel (1967) Immunological studies concerning the nephritis of systemic lupus erythematosus. J. Exp. Med. 126 607-624.
    • (1967) J. Exp. Med. , vol.126 , pp. 607-624
    • Koffler, D.1    Schur, P.H.2    Kunkel, H.G.3
  • 80
    • 0029862164 scopus 로고    scopus 로고
    • Increased expression of CD40 ligand on systemic lupus erythematosus lymphocytes
    • M. Koshy, D. Berger and M.K. Crow (1996) Increased expression of CD40 ligand on systemic lupus erythematosus lymphocytes. J. Clin. Invest. 98 826-837.
    • (1996) J. Clin. Invest. , vol.98 , pp. 826-837
    • Koshy, M.1    Berger, D.2    Crow, M.K.3
  • 81
    • 0030560974 scopus 로고    scopus 로고
    • Defective CD3-mediated cell death in activated T cells from patients with systemic lupus erythematosus: role of decreased intracellular TNF-alpha
    • B. Kovacs, D. Vassilopoulos, S.A. Vogelgesang and G.C. Tsokos (1996) Defective CD3-mediated cell death in activated T cells from patients with systemic lupus erythematosus: role of decreased intracellular TNF-alpha. Clin. Immunol. Immunopathol. 81 293-302.
    • (1996) Clin. Immunol. Immunopathol. , vol.81 , pp. 293-302
    • Kovacs, B.1    Vassilopoulos, D.2    Vogelgesang, S.A.3    Tsokos, G.C.4
  • 83
    • 2942586874 scopus 로고    scopus 로고
    • Alterations in lipid raft composition and dynamics contribute to abnormal T cell responses in systemic lupus erythematosus
    • S. Krishnan, M.P. Nambiar, V.G. Warke, C.U. Fisher, J. Mitchell, N. Delaney and G.C. Tsokos (2004) Alterations in lipid raft composition and dynamics contribute to abnormal T cell responses in systemic lupus erythematosus. J. Immunol. 172 7821-7831.
    • (2004) J. Immunol. , vol.172 , pp. 7821-7831
    • Krishnan, S.1    Nambiar, M.P.2    Warke, V.G.3    Fisher, C.U.4    Mitchell, J.5    Delaney, N.6    Tsokos, G.C.7
  • 84
    • 0029006389 scopus 로고
    • How can cryptic epitopes trigger autoimmunity?
    • A. Lanzavecchia (1995) How can cryptic epitopes trigger autoimmunity? J. Exp. Med. 181 1945-1948.
    • (1995) J. Exp. Med. , vol.181 , pp. 1945-1948
    • Lanzavecchia, A.1
  • 86
    • 0030209793 scopus 로고    scopus 로고
    • Murine glomerulotropic monoclonal antibodies are highly oligoclonal and exhibit distinctive molecular features
    • J.B. Lefkowith, R. Di Valerio, J. Norris, G.D. Glick, A.L. Alexander, L. Jackson and G.S. Gilkeson (1996) Murine glomerulotropic monoclonal antibodies are highly oligoclonal and exhibit distinctive molecular features. J. Immunol. 157 1297-1305.
    • (1996) J. Immunol. , vol.157 , pp. 1297-1305
    • Lefkowith, J.B.1    Di Valerio, R.2    Norris, J.3    Glick, G.D.4    Alexander, A.L.5    Jackson, L.6    Gilkeson, G.S.7
  • 87
    • 0029899083 scopus 로고    scopus 로고
    • Nephritogenic autoantibodies in lupus: current concepts and continuing controversies
    • J.B. Lefkowith and G.S. Gilkeson (1996) Nephritogenic autoantibodies in lupus: current concepts and continuing controversies. Arthritis Rheum. 39 894-903.
    • (1996) Arthritis Rheum. , vol.39 , pp. 894-903
    • Lefkowith, J.B.1    Gilkeson, G.S.2
  • 88
    • 1342300520 scopus 로고    scopus 로고
    • Pathogenic profiles and molecular signatures of anti-nuclear autoantibodies rescued from NZM2410 lupus mice
    • Z. Liang, C. Xie, C. Chen, D. Kreska, K. Hsu, L. Li, X. Zhou and C. Mohan (2004) Pathogenic profiles and molecular signatures of anti-nuclear autoantibodies rescued from NZM2410 lupus mice. J. Exp. Med. 199 381-398.
    • (2004) J. Exp. Med. , vol.199 , pp. 381-398
    • Liang, Z.1    Xie, C.2    Chen, C.3    Kreska, D.4    Hsu, K.5    Li, L.6    Zhou, X.7    Mohan, C.8
  • 89
    • 0032036481 scopus 로고    scopus 로고
    • Altered pattern of TCR/CD3-mediated protein-tyrosyl phosphorylation in T cells from patients with systemic lupus erythematosus. Deficient expression of the T cell receptor zeta chain
    • S.N. Liossis, X.Z. Ding, G.J. Dennis and G.C. Tsokos (1998) Altered pattern of TCR/CD3-mediated protein-tyrosyl phosphorylation in T cells from patients with systemic lupus erythematosus. Deficient expression of the T cell receptor zeta chain. J. Clin. Invest. 101 1448-1457.
    • (1998) J. Clin. Invest. , vol.101 , pp. 1448-1457
    • Liossis, S.N.1    Ding, X.Z.2    Dennis, G.J.3    Tsokos, G.C.4
  • 90
    • 0029829026 scopus 로고    scopus 로고
    • B cells from patients with systemic lupus erythematosus display abnormal antigen receptor-mediated early signal transduction events
    • S.N. Liossis, B. Kovacs, G. Dennis, G.M. Kammer and G.C. Tsokos (1996) B cells from patients with systemic lupus erythematosus display abnormal antigen receptor-mediated early signal transduction events. J. Clin. Invest. 98 2549-2557.
    • (1996) J. Clin. Invest. , vol.98 , pp. 2549-2557
    • Liossis, S.N.1    Kovacs, B.2    Dennis, G.3    Kammer, G.M.4    Tsokos, G.C.5
  • 91
    • 1342267617 scopus 로고    scopus 로고
    • Decreased CD4+CD25+ T cells in peripheral blood of patients with systemic lupus erythematosus
    • M.F. Liu, C.R. Wang, L.L. Fung and C.R. Wu (2004) Decreased CD4+CD25+ T cells in peripheral blood of patients with systemic lupus erythematosus. Scand. J. Immunol. 59 198-202.
    • (2004) Scand. J. Immunol. , vol.59 , pp. 198-202
    • Liu, M.F.1    Wang, C.R.2    Fung, L.L.3    Wu, C.R.4
  • 92
    • 0028052210 scopus 로고
    • In vivo production of interleukin-10 by non-T cells in rheumatoid arthritis, Sjogren's syndrome, and systemic lupus erythematosus. A potential mechanism of B lymphocyte hyperactivity and autoimmunity
    • L. Llorente, Y. Richaud-Patin, R. Fior, J. Alcocer-Varela, J. Wijdenes, B.M. Fourrier, P. Galanaud and D. Emilie (1994) In vivo production of interleukin-10 by non-T cells in rheumatoid arthritis, Sjogren's syndrome, and systemic lupus erythematosus. A potential mechanism of B lymphocyte hyperactivity and autoimmunity. Arthritis Rheum. 37 1647-1655.
    • (1994) Arthritis Rheum. , vol.37 , pp. 1647-1655
    • Llorente, L.1    Richaud-Patin, Y.2    Fior, R.3    Alcocer-Varela, J.4    Wijdenes, J.5    Fourrier, B.M.6    Galanaud, P.7    Emilie, D.8
  • 95
    • 0032728568 scopus 로고    scopus 로고
    • Major peptide autoepitopes for nucleosome-specific T cells of human lupus
    • L. Lu, A. Kaliyaperumal, D.T. Boumpas and S.K. Datta (1999) Major peptide autoepitopes for nucleosome-specific T cells of human lupus. J. Clin. Invest. 104 345-355.
    • (1999) J. Clin. Invest. , vol.104 , pp. 345-355
    • Lu, L.1    Kaliyaperumal, A.2    Boumpas, D.T.3    Datta, S.K.4
  • 96
    • 0029939451 scopus 로고    scopus 로고
    • Autoimmune lpr/lpr mice deficient in CD40 ligand: spontaneous immunoglobulin class switching with dichotomy of autoantibody responses
    • J. Ma, J. Xu, Q. Peng, J. Zhang, I.S. Grewal, R.A. Flavell and J. Craft (1996) Autoimmune lpr/lpr mice deficient in CD40 ligand: spontaneous immunoglobulin class switching with dichotomy of autoantibody responses. J. Immunol. 157 417-426.
    • (1996) J. Immunol. , vol.157 , pp. 417-426
    • Ma, J.1    Xu, J.2    Peng, Q.3    Zhang, J.4    Grewal, I.S.5    Flavell, R.A.6    Craft, J.7
  • 97
    • 0023277281 scopus 로고
    • Murine monoclonal anti-DNA antibodies bind directly to glomerular antigens and form immune deposits
    • M.P. Madaio, J. Carlson, J. Cataldo, A. Ucci, P. Migliorini and O. Pankewyez (1987) Murine monoclonal anti-DNA antibodies bind directly to glomerular antigens and form immune deposits. J. Immunol. 138 2883-2889.
    • (1987) J. Immunol. , vol.138 , pp. 2883-2889
    • Madaio, M.P.1    Carlson, J.2    Cataldo, J.3    Ucci, A.4    Migliorini, P.5    Pankewyez, O.6
  • 98
    • 0025054661 scopus 로고
    • Interclonal and intraclonal diversity among anti-DNA antibodies from an (NZB × NZW)F1 mouse
    • T.N. Marion, D.M. Tillman and N. Jou (1990) Interclonal and intraclonal diversity among anti-DNA antibodies from an (NZB × NZW)F1 mouse. J. Immunol. 145 2322-2332.
    • (1990) J. Immunol. , vol.145 , pp. 2322-2332
    • Marion, T.N.1    Tillman, D.M.2    Jou, N.3
  • 100
    • 8544242704 scopus 로고    scopus 로고
    • Regulatory T cells: friend or foe in immunity to infection?
    • K.H. Mills (2004) Regulatory T cells: friend or foe in immunity to infection? Nat. Rev. Immunol. 4 841-855.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 841-855
    • Mills, K.H.1
  • 101
    • 0027477318 scopus 로고
    • Nucleosome: a major immunogen for pathogenic autoantibody-inducing T cells of lupus
    • C. Mohan, S. Adams, V. Stanik and S.K. Datta (1993) Nucleosome: a major immunogen for pathogenic autoantibody-inducing T cells of lupus. J. Exp. Med. 177 1367-1381.
    • (1993) J. Exp. Med. , vol.177 , pp. 1367-1381
    • Mohan, C.1    Adams, S.2    Stanik, V.3    Datta, S.K.4
  • 103
    • 0028852328 scopus 로고
    • Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis
    • C. Mohan, Y. Shi, J.D. Laman and S.K. Datta (1995) Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis. J. Immunol. 154 1470-1480.
    • (1995) J. Immunol. , vol.154 , pp. 1470-1480
    • Mohan, C.1    Shi, Y.2    Laman, J.D.3    Datta, S.K.4
  • 104
    • 0031570375 scopus 로고    scopus 로고
    • Functional dissection of systemic lupus erythematosus using congenic mouse strains
    • L. Morel, C. Mohan, Y. Yu, B.P. Croker, N. Tian, A. Deng and E.K. Wakeland (1997) Functional dissection of systemic lupus erythematosus using congenic mouse strains. J. Immunol. 158 6019-6028.
    • (1997) J. Immunol. , vol.158 , pp. 6019-6028
    • Morel, L.1    Mohan, C.2    Yu, Y.3    Croker, B.P.4    Tian, N.5    Deng, A.6    Wakeland, E.K.7
  • 107
    • 0025334066 scopus 로고
    • V region sequences of an idiotypically connected family of pathogenic anti-DNA autoantibodies
    • T.L. O'Keefe, S. Bandyopadhyay, S.K. Datta and T. Imanishi-Kari (1990) V region sequences of an idiotypically connected family of pathogenic anti-DNA autoantibodies. J. Immunol. 144 4275-4283.
    • (1990) J. Immunol. , vol.144 , pp. 4275-4283
    • O'Keefe, T.L.1    Bandyopadhyay, S.2    Datta, S.K.3    Imanishi-Kari, T.4
  • 108
    • 0033583479 scopus 로고    scopus 로고
    • Deficiency in CD22, a B cell-specific inhibitory receptor, is sufficient to predispose to development of high affinity autoantibodies
    • T.L. O'Keefe, G.T. Williams, F.D. Batista and M.S. Neuberger (1999) Deficiency in CD22, a B cell-specific inhibitory receptor, is sufficient to predispose to development of high affinity autoantibodies. J. Exp. Med. 189 1307-1313.
    • (1999) J. Exp. Med. , vol.189 , pp. 1307-1313
    • O'Keefe, T.L.1    Williams, G.T.2    Batista, F.D.3    Neuberger, M.S.4
  • 110
    • 0031961344 scopus 로고    scopus 로고
    • Elevated interleukin-10 levels correlated with disease activity in systemic lupus erythematosus
    • Y.B. Park, S.K. Lee, D.S. Kim, J. Lee, C.H. Lee and C.H. Song (1998) Elevated interleukin-10 levels correlated with disease activity in systemic lupus erythematosus. Clin. Exp. Rheumatol. 16 283-288.
    • (1998) Clin. Exp. Rheumatol. , vol.16 , pp. 283-288
    • Park, Y.B.1    Lee, S.K.2    Kim, D.S.3    Lee, J.4    Lee, C.H.5    Song, C.H.6
  • 111
    • 0242556891 scopus 로고    scopus 로고
    • Toll-like receptors: balancing host resistance with immune tolerance
    • C. Pasare and R. Medzhitov (2003) Toll-like receptors: balancing host resistance with immune tolerance. Curr. Opin. Immunol. 15 677-682.
    • (2003) Curr. Opin. Immunol. , vol.15 , pp. 677-682
    • Pasare, C.1    Medzhitov, R.2
  • 112
    • 0030589227 scopus 로고    scopus 로고
    • Induction of non-pathologic, humoral autoimmunity in lupus-prone mice by a class II-restricted, transgenic ab T cell: separation of autoantigen-specific and-nonspecific help
    • S.L. Peng, S. Fatenejad and J. Craft (1996) Induction of non-pathologic, humoral autoimmunity in lupus-prone mice by a class II-restricted, transgenic ab T cell: separation of autoantigen-specific and-nonspecific help. J. Immunol. 157 5225-5230.
    • (1996) J. Immunol. , vol.157 , pp. 5225-5230
    • Peng, S.L.1    Fatenejad, S.2    Craft, J.3
  • 116
    • 0037436121 scopus 로고    scopus 로고
    • Immunology. Regulating the regulators
    • F. Powrie and K.J. Maloy (2003) Immunology. Regulating the regulators. Science 299 1030-1031.
    • (2003) Science , vol.299 , pp. 1030-1031
    • Powrie, F.1    Maloy, K.J.2
  • 117
    • 0032744680 scopus 로고    scopus 로고
    • Low levels of interferon-alpha induce CD86 (B7.2) expression and accelerates dendritic cell maturation from human peripheral blood mononuclear cells
    • L.G. Radvanyi, A. Banerjee, M. Weir and H. Messner (1999) Low levels of interferon-alpha induce CD86 (B7.2) expression and accelerates dendritic cell maturation from human peripheral blood mononuclear cells. Scand. J. Immunol. 50 499-509.
    • (1999) Scand. J. Immunol. , vol.50 , pp. 499-509
    • Radvanyi, L.G.1    Banerjee, A.2    Weir, M.3    Messner, H.4
  • 118
    • 0025123503 scopus 로고
    • Pathogenic anti-DNA autoantibody-inducing T helper cell lines from patients with active lupus nephritis: isolation of CD4-8-T helper cell lines that express the gamma delta T-cell antigen receptor
    • S. Rajagopalan, T. Zordan, G.C. Tsokos and S.K. Datta (1990) Pathogenic anti-DNA autoantibody-inducing T helper cell lines from patients with active lupus nephritis: isolation of CD4-8-T helper cell lines that express the gamma delta T-cell antigen receptor. Proc. Natl. Acad. Sci. U.S.A. 87 7020-7024.
    • (1990) Proc. Natl. Acad. Sci. U.S.A. , vol.87 , pp. 7020-7024
    • Rajagopalan, S.1    Zordan, T.2    Tsokos, G.C.3    Datta, S.K.4
  • 119
    • 0027518589 scopus 로고
    • Cross-reactions of anti-DNA autoantibodies with cell surface proteins
    • E. Raz, H. Ben-Bassat, T. Davidi, Z. Shlomai and D. Eilat (1993) Cross-reactions of anti-DNA autoantibodies with cell surface proteins. Eur. J. Immunol. 23 383-390.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 383-390
    • Raz, E.1    Ben-Bassat, H.2    Davidi, T.3    Shlomai, Z.4    Eilat, D.5
  • 120
    • 0024506642 scopus 로고
    • Anti-DNA anti-bodies bind directly to renal antigens and induce kidney dysfunction in the isolated perfused rat kidney
    • E. Raz, M. Brezis, E. Rosenmann and D. Eilat (1989) Anti-DNA anti-bodies bind directly to renal antigens and induce kidney dysfunction in the isolated perfused rat kidney. J. Immunol. 142 3076-3082.
    • (1989) J. Immunol. , vol.142 , pp. 3076-3082
    • Raz, E.1    Brezis, M.2    Rosenmann, E.3    Eilat, D.4
  • 121
    • 0019474802 scopus 로고
    • Polyclonal B-cell activation of autoantibodies (CBA/N × NZB)F1 mice by polyinosinic polycytidylic acid
    • J.P. Reeves, J.D. Taurog and A.D. Steinberg (1981) Polyclonal B-cell activation of autoantibodies (CBA/N × NZB)F1 mice by polyinosinic polycytidylic acid. Clin. Immunol. Immunopathol. 19 170-180.
    • (1981) Clin. Immunol. Immunopathol. , vol.19 , pp. 170-180
    • Reeves, J.P.1    Taurog, J.D.2    Steinberg, A.D.3
  • 122
    • 0026648711 scopus 로고
    • Development of autoimmune disease in SCID mice populated with long-term “in vitro” proliferating (NZB × NZW)F1 pre-B cells
    • L. Reininger, T. Radaszkiewicz, M. Kosco, F. Melchers and A.G. Rolink (1992) Development of autoimmune disease in SCID mice populated with long-term “in vitro” proliferating (NZB × NZW)F1 pre-B cells. J. Exp. Med. 176 1343-1353.
    • (1992) J. Exp. Med. , vol.176 , pp. 1343-1353
    • Reininger, L.1    Radaszkiewicz, T.2    Kosco, M.3    Melchers, F.4    Rolink, A.G.5
  • 123
    • 0028931042 scopus 로고
    • Breakdown of B cell tolerance in a mouse model of systemic lupus erythematosus
    • J.H. Roark, C.L. Kuntz, K.A. Nguyen, A.J. Caton and J. Erikson (1995) Breakdown of B cell tolerance in a mouse model of systemic lupus erythematosus. J. Exp. Med. 181 1157-1167.
    • (1995) J. Exp. Med. , vol.181 , pp. 1157-1167
    • Roark, J.H.1    Kuntz, C.L.2    Nguyen, K.A.3    Caton, A.J.4    Erikson, J.5
  • 124
    • 0029071783 scopus 로고
    • B cell selection and allelic exclusion of an anti-DNA Ig transgene in MRL-lpr/lpr mice
    • J.H. Roark, C.L. Kuntz, K.A. Nguyen, L. Mandik, M. Cattermole and J. Erikson (1995) B cell selection and allelic exclusion of an anti-DNA Ig transgene in MRL-lpr/lpr mice. J. Immunol. 154 4444-4455.
    • (1995) J. Immunol. , vol.154 , pp. 4444-4455
    • Roark, J.H.1    Kuntz, C.L.2    Nguyen, K.A.3    Mandik, L.4    Cattermole, M.5    Erikson, J.6
  • 125
    • 0035423557 scopus 로고    scopus 로고
    • An etiopathogenic role for the type I IFN system in SLE
    • L. Ronnblom and G.V. Alm (2001) An etiopathogenic role for the type I IFN system in SLE. Trends Immunol. 22 427-431.
    • (2001) Trends Immunol. , vol.22 , pp. 427-431
    • Ronnblom, L.1    Alm, G.V.2
  • 126
    • 0035905409 scopus 로고    scopus 로고
    • A pivotal role for the natural interferon alpha-producing cells (plasmacytoid dendritic cells) in the pathogenesis of lupus
    • L. Ronnblom and G.V. Alm (2001) A pivotal role for the natural interferon alpha-producing cells (plasmacytoid dendritic cells) in the pathogenesis of lupus. J. Exp. Med. 194 F59-F63.
    • (2001) J. Exp. Med. , vol.194 , pp. F59-F63
    • Ronnblom, L.1    Alm, G.V.2
  • 127
    • 0037214074 scopus 로고    scopus 로고
    • Immune complexes from SLE sera induce IL10 production from normal peripheral blood mononuclear cells by an FegammaRII dependent mechanism: implications for a possible vicious cycle maintaining B cell hyperactivity in SLE
    • J. Ronnelid, A. Tejde, L. Mathsson, K. Nilsson-Ekdahl and B. Nilsson (2003) Immune complexes from SLE sera induce IL10 production from normal peripheral blood mononuclear cells by an FegammaRII dependent mechanism: implications for a possible vicious cycle maintaining B cell hyperactivity in SLE. Ann. Rheum. Dis. 62 37-42.
    • (2003) Ann. Rheum. Dis. , vol.62 , pp. 37-42
    • Ronnelid, J.1    Tejde, A.2    Mathsson, L.3    Nilsson-Ekdahl, K.4    Nilsson, B.5
  • 128
    • 0028283552 scopus 로고
    • Evidence for polyclonal T cell activation in murine models of systemic lupus erythematosus
    • S.J. Rozzo, C.G. Drake, B.L. Chiang, M.E. Gershwin and B.L. Kotzin (1994) Evidence for polyclonal T cell activation in murine models of systemic lupus erythematosus. J. Immunol. 153 1340-1351.
    • (1994) J. Immunol. , vol.153 , pp. 1340-1351
    • Rozzo, S.J.1    Drake, C.G.2    Chiang, B.L.3    Gershwin, M.E.4    Kotzin, B.L.5
  • 129
    • 0037501347 scopus 로고    scopus 로고
    • Resistance to CpG DNA-induced autoimmunity through tolerogenic B cell antigen receptor ERK signaling
    • L. Rui, C.G. Vinuesa, J. Blasioli and C.C. Goodnow (2003) Resistance to CpG DNA-induced autoimmunity through tolerogenic B cell antigen receptor ERK signaling. Nat. Immunol. 4 594-600.
    • (2003) Nat. Immunol. , vol.4 , pp. 594-600
    • Rui, L.1    Vinuesa, C.G.2    Blasioli, J.3    Goodnow, C.C.4
  • 130
    • 0030788684 scopus 로고    scopus 로고
    • G1 arrest and high expression of cyclin kinase and apoptosis inhibitors in accumulated activated/memory phenotype CD4+ cells of older lupus mice
    • H. Sabzevari, S. Propp, D.H. Kono and A.N. Theofilopoulos (1997) G1 arrest and high expression of cyclin kinase and apoptosis inhibitors in accumulated activated/memory phenotype CD4+ cells of older lupus mice. Eur. J. Immunol. 27 1901-1910.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 1901-1910
    • Sabzevari, H.1    Propp, S.2    Kono, D.H.3    Theofilopoulos, A.N.4
  • 131
    • 0019513161 scopus 로고
    • Isolation of DNA from DNA/anti-DNA antibody immune complexes in systemic lupus erythematosus
    • H. Sano and C. Morimoto (1981) Isolation of DNA from DNA/anti-DNA antibody immune complexes in systemic lupus erythematosus. J. Immunol. 126 538-539.
    • (1981) J. Immunol. , vol.126 , pp. 538-539
    • Sano, H.1    Morimoto, C.2
  • 133
    • 0023896085 scopus 로고
    • The contribution of L3T4+ T cells to lymphoproliferation and autoantibody production in MRL-lpr/lpr mice
    • T.J. Santoro, J.P. Portanova and B.L. Kotzin (1988) The contribution of L3T4+ T cells to lymphoproliferation and autoantibody production in MRL-lpr/lpr mice. J. Exp. Med. 167 1713-1718.
    • (1988) J. Exp. Med. , vol.167 , pp. 1713-1718
    • Santoro, T.J.1    Portanova, J.P.2    Kotzin, B.L.3
  • 134
    • 0024403795 scopus 로고
    • Histones have high affinity for the glomerular basement membrane. Relevance for immune complex formation in lupus nephritis
    • T.M. Schmiedeke, F.W. Stockl, R. Weber, Y. Sugisaki, S.R. Batsford and A. Vogt (1989) Histones have high affinity for the glomerular basement membrane. Relevance for immune complex formation in lupus nephritis. J. Exp. Med. 169 1879-1894.
    • (1989) J. Exp. Med. , vol.169 , pp. 1879-1894
    • Schmiedeke, T.M.1    Stockl, F.W.2    Weber, R.3    Sugisaki, Y.4    Batsford, S.R.5    Vogt, A.6
  • 135
    • 0034084162 scopus 로고    scopus 로고
    • Regulatory T cells in autoimmunity
    • E.M. Shevach (2000) Regulatory T cells in autoimmunity. Annu. Rev. Immunol. 18 423-449.
    • (2000) Annu. Rev. Immunol. , vol.18 , pp. 423-449
    • Shevach, E.M.1
  • 136
    • 0035525528 scopus 로고    scopus 로고
    • From T to B and back again: positive feedback in systemic autoimmune diseas
    • M.J. Shlomchik, J.E. Craft and M.J. Mamula (2001) From T to B and back again: positive feedback in systemic autoimmune diseas. Nat. Rev. Immunol. 1 147-153.
    • (2001) Nat. Rev. Immunol. , vol.1 , pp. 147-153
    • Shlomchik, M.J.1    Craft, J.E.2    Mamula, M.J.3
  • 140
    • 0028485743 scopus 로고
    • The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice
    • G.G. Singer and A.K. Abbas (1994) The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice. Immunity 1 365-373.
    • (1994) Immunity , vol.1 , pp. 365-373
    • Singer, G.G.1    Abbas, A.K.2
  • 141
    • 0029069499 scopus 로고
    • T cell determinants from autoantibodies to DNA can upregulate autoimmunity in murine systemic lupus erythematosus
    • R.R. Singh, V. Kumar, F.M. Ebling, S. Southwood, A. Sette, E.E. Sercarz and B.H. Hahn (1995) T cell determinants from autoantibodies to DNA can upregulate autoimmunity in murine systemic lupus erythematosus. J. Exp. Med. 181 2017-2027.
    • (1995) J. Exp. Med. , vol.181 , pp. 2017-2027
    • Singh, R.R.1    Kumar, V.2    Ebling, F.M.3    Southwood, S.4    Sette, A.5    Sercarz, E.E.6    Hahn, B.H.7
  • 142
    • 0036785632 scopus 로고    scopus 로고
    • Genetic dissection of systemic lupus erythematosus pathogenesis: evidence for functional expression of Sle3/5 by non-T cells
    • E.S. Sobel, L. Morel, R. Baert, C. Mohan, J. Schiffenbauer and E.K. Wakeland (2002) Genetic dissection of systemic lupus erythematosus pathogenesis: evidence for functional expression of Sle3/5 by non-T cells. J. Immunol. 169 4025-4032.
    • (2002) J. Immunol. , vol.169 , pp. 4025-4032
    • Sobel, E.S.1    Morel, L.2    Baert, R.3    Mohan, C.4    Schiffenbauer, J.5    Wakeland, E.K.6
  • 143
    • 0018935423 scopus 로고
    • Effects of thymectomy or androgen administration upon the autoimmune disease of MRL/Mp-lpr/lpr mice
    • A.D. Steinberg, J.B. Roths, E.D. Murphy, R.T. Steinberg and E.S. Raveche (1980) Effects of thymectomy or androgen administration upon the autoimmune disease of MRL/Mp-lpr/lpr mice. J. Immunol. 125 871-873.
    • (1980) J. Immunol. , vol.125 , pp. 871-873
    • Steinberg, A.D.1    Roths, J.B.2    Murphy, E.D.3    Steinberg, R.T.4    Raveche, E.S.5
  • 144
    • 0028921921 scopus 로고
    • Impaired polyclonal T cell cytolytic activity. A possible risk factor for systemic lupus erythematosus
    • W. Stohl (1995) Impaired polyclonal T cell cytolytic activity. A possible risk factor for systemic lupus erythematosus. Arthritis Rheum. 38 506-516.
    • (1995) Arthritis Rheum. , vol.38 , pp. 506-516
    • Stohl, W.1
  • 145
    • 0024518559 scopus 로고
    • Antinuclear antibodies: Diagnostic markers for autoimmune diseases and probes for cell biology
    • E.M. Tan (1989) Antinuclear antibodies: Diagnostic markers for autoimmune diseases and probes for cell biology. Adv. Immunol. 44 93-151.
    • (1989) Adv. Immunol. , vol.44 , pp. 93-151
    • Tan, E.M.1
  • 146
    • 0029150696 scopus 로고
    • Apoptosis, nucleosomes, and nephritis in systemic lupus erythematosus [editorial]
    • W.J. Tax, C. Kramers, M.C. van Bruggen and J.H. Berden (1995) Apoptosis, nucleosomes, and nephritis in systemic lupus erythematosus [editorial]. Kidney Int. 48 666-673.
    • (1995) Kidney Int. , vol.48 , pp. 666-673
    • Tax, W.J.1    Kramers, C.2    van Bruggen, M.C.3    Berden, J.H.4
  • 147
    • 0038062836 scopus 로고    scopus 로고
    • Rewiring the T-cell: signaling defects and novel prospects for the treatment of SLE
    • G.C. Tsokos, M.P. Nambiar, K. Tenbrock and Y.T. Juang (2003) Rewiring the T-cell: signaling defects and novel prospects for the treatment of SLE. Trends Immunol. 24 259-263.
    • (2003) Trends Immunol. , vol.24 , pp. 259-263
    • Tsokos, G.C.1    Nambiar, M.P.2    Tenbrock, K.3    Juang, Y.T.4
  • 148
    • 0021966127 scopus 로고
    • Interleukin-2 restores the depressed allogeneic cell-mediated lympholysis and natural killer cell activity in patients with systemic lupus erythematosus
    • G.C. Tsokos, P.L. Smith, C.B. Christian, R.N. Lipnick, J.E. Balow and J.Y. Djeu (1985) Interleukin-2 restores the depressed allogeneic cell-mediated lympholysis and natural killer cell activity in patients with systemic lupus erythematosus. Clin. Immunol. Immunopathol. 34 379-386.
    • (1985) Clin. Immunol. Immunopathol. , vol.34 , pp. 379-386
    • Tsokos, G.C.1    Smith, P.L.2    Christian, C.B.3    Lipnick, R.N.4    Balow, J.E.5    Djeu, J.Y.6
  • 149
    • 0035018659 scopus 로고    scopus 로고
    • The effect of interleukin-10 and of interleukin-12 on the in vitro production of antidouble-stranded DNA antibodies from patients with systemic lupus erythematosus
    • J. Tyrrell-Price, P.M. Lydyard and D.A. Isenberg (2001) The effect of interleukin-10 and of interleukin-12 on the in vitro production of antidouble-stranded DNA antibodies from patients with systemic lupus erythematosus. Clin. Exp. Immunol. 124 118-125.
    • (2001) Clin. Exp. Immunol. , vol.124 , pp. 118-125
    • Tyrrell-Price, J.1    Lydyard, P.M.2    Isenberg, D.A.3
  • 150
    • 0032940010 scopus 로고    scopus 로고
    • Elevated levels and functional capacity of soluble CD40 ligand in systemic lupus erythematosus sera
    • R.K. Vakkalanka, C. Woo, K.A. Kirou, M. Kosby, D. Berger and M.K. Crow (1999) Elevated levels and functional capacity of soluble CD40 ligand in systemic lupus erythematosus sera. Arthritis Rheum. 42 871-881.
    • (1999) Arthritis Rheum. , vol.42 , pp. 871-881
    • Vakkalanka, R.K.1    Woo, C.2    Kirou, K.A.3    Kosby, M.4    Berger, D.5    Crow, M.K.6
  • 151
    • 0029164734 scopus 로고
    • TCR/CD3 complex-mediated signal transduction pathway in T cells and T cell lines from patients with systemic lupus erythematosus
    • D. Vassilopoulos, B. Kovacs and G.C. Tsokos (1995) TCR/CD3 complex-mediated signal transduction pathway in T cells and T cell lines from patients with systemic lupus erythematosus. J. Immunol. 155 2269-2281.
    • (1995) J. Immunol. , vol.155 , pp. 2269-2281
    • Vassilopoulos, D.1    Kovacs, B.2    Tsokos, G.C.3
  • 153
    • 0026814959 scopus 로고
    • Murine monoclonal anti-DNA antibodies penetrate cells, bind to nuclei, and induce glomerular proliferation and proteinuria in vivo
    • D. Vlahakos, M.H. Foster, A.A. Ucci, K.J. Barrett, S.K. Datta and M.P. Madaio (1992) Murine monoclonal anti-DNA antibodies penetrate cells, bind to nuclei, and induce glomerular proliferation and proteinuria in vivo. J. Am. Soc. Nephrol. 2 1345-1354.
    • (1992) J. Am. Soc. Nephrol. , vol.2 , pp. 1345-1354
    • Vlahakos, D.1    Foster, M.H.2    Ucci, A.A.3    Barrett, K.J.4    Datta, S.K.5    Madaio, M.P.6
  • 154
    • 0041437738 scopus 로고    scopus 로고
    • Systemic lupus erythematosus
    • K.F. Austen, M.M. Frank, J.P. Atkinson, H. Cantor (Eds), Philadelphia: Lippincott Williams & Wilkins
    • G. Vratsanos, I. Kang and J. Craft (2001) Systemic lupus erythematosus. K.F. Austen, M.M. Frank, J.P. Atkinson, H. Cantor (Eds) Samter's Immunologic Diseases Philadelphia: Lippincott Williams & Wilkins 475-495.
    • (2001) Samter's Immunologic Diseases , pp. 475-495
    • Vratsanos, G.1    Kang, I.2    Craft, J.3
  • 155
    • 0035808778 scopus 로고    scopus 로고
    • CD4(+) T cells from lupus-prone mice are hyperresponsive to T cell receptor engagement with low and high affinity peptide antigens. A model to explain spontaneous T cell activation in lupus
    • G.S. Vratsanos, S. Jung, Y.M. Park and J. Craft (2001) CD4(+) T cells from lupus-prone mice are hyperresponsive to T cell receptor engagement with low and high affinity peptide antigens. A model to explain spontaneous T cell activation in lupus. J. Exp. Med. 193 329-338.
    • (2001) J. Exp. Med. , vol.193 , pp. 329-338
    • Vratsanos, G.S.1    Jung, S.2    Park, Y.M.3    Craft, J.4
  • 156
    • 0025210133 scopus 로고
    • Normal mitogen-induced suppression of the interleukin-6 (IL-6) response and its deficiency in systemic lupus erythematosus
    • R.J. Warrington and W.J. Rutherford (1990) Normal mitogen-induced suppression of the interleukin-6 (IL-6) response and its deficiency in systemic lupus erythematosus. J. Clin. Immunol. 10 52-60.
    • (1990) J. Clin. Immunol. , vol.10 , pp. 52-60
    • Warrington, R.J.1    Rutherford, W.J.2
  • 157
    • 0021940256 scopus 로고
    • Treatment of murine lupus with monoclonal anti-T cell antibody
    • D. Wofsy, J.A. Ledbetter, P.L. Hendler and W.E. Seaman (1985) Treatment of murine lupus with monoclonal anti-T cell antibody. J. Immunol. 134 852-857.
    • (1985) J. Immunol. , vol.134 , pp. 852-857
    • Wofsy, D.1    Ledbetter, J.A.2    Hendler, P.L.3    Seaman, W.E.4
  • 158
    • 0033179001 scopus 로고    scopus 로고
    • Abnormal NF-kappa B activity in T lymphocytes from patients with systemic lupus erythematosus is associated with decreased p65-RelA protein expression
    • H.K. Wong, G.M. Kammer, G. Dennis and G.C. Tsokos (1999) Abnormal NF-kappa B activity in T lymphocytes from patients with systemic lupus erythematosus is associated with decreased p65-RelA protein expression. J. Immunol. 163 1682-1689.
    • (1999) J. Immunol. , vol.163 , pp. 1682-1689
    • Wong, H.K.1    Kammer, G.M.2    Dennis, G.3    Tsokos, G.C.4
  • 159
    • 0035970783 scopus 로고    scopus 로고
    • Effect of LPS on the permeability of the blood-brain barrier to insulin
    • H. Xaio, W.A. Banks, M.L. Niehoff and J.E. Morley (2001) Effect of LPS on the permeability of the blood-brain barrier to insulin. Brain Res. 896 36-42.
    • (2001) Brain Res. , vol.896 , pp. 36-42
    • Xaio, H.1    Banks, W.A.2    Niehoff, M.L.3    Morley, J.E.4
  • 160
    • 1942454327 scopus 로고    scopus 로고
    • Human lupus T cells resist inactivation and escape death by upregulating COX-2
    • L. Xu, L. Zhang, Y. Yi, H.K. Kang and S.K. Datta (2004) Human lupus T cells resist inactivation and escape death by upregulating COX-2. Nat. Med. 10 411-415.
    • (2004) Nat. Med. , vol.10 , pp. 411-415
    • Xu, L.1    Zhang, L.2    Yi, Y.3    Kang, H.K.4    Datta, S.K.5
  • 161
    • 0036533552 scopus 로고    scopus 로고
    • Autoreactive T cells revealed in the normal repertoire: escape from negative selection and peripheral tolerance
    • J. Yan and M.J. Mamula (2002) Autoreactive T cells revealed in the normal repertoire: escape from negative selection and peripheral tolerance. J. Immunol. 168 3188-3194.
    • (2002) J. Immunol. , vol.168 , pp. 3188-3194
    • Yan, J.1    Mamula, M.J.2
  • 162
    • 0034541176 scopus 로고    scopus 로고
    • Regulatory defects in Cbl and mitogen-activated protein kinase (extracellular signal-related kinase) pathways cause persistent hyperexpression of CD40 ligand in human lupus T cells
    • Y. Yi, M. McNerney and S.K. Datta (2000) Regulatory defects in Cbl and mitogen-activated protein kinase (extracellular signal-related kinase) pathways cause persistent hyperexpression of CD40 ligand in human lupus T cells. J. Immunol. 165 6627-6634.
    • (2000) J. Immunol. , vol.165 , pp. 6627-6634
    • Yi, Y.1    McNerney, M.2    Datta, S.K.3
  • 164
    • 17044393073 scopus 로고    scopus 로고
    • Naive CD4+ T cells from lupus-prone Fas-intact MRL mice display TCR-mediated hyper-proliferation due to intrinsic threshold defects in activation
    • C.E. Zielinski, S.N. Jacob, F. Bouzahzah, B.E. Ehrlich and J. Craft (2005) Naive CD4+ T cells from lupus-prone Fas-intact MRL mice display TCR-mediated hyper-proliferation due to intrinsic threshold defects in activation. J. Immunol. 174 5100-5109.
    • (2005) J. Immunol. , vol.174 , pp. 5100-5109
    • Zielinski, C.E.1    Jacob, S.N.2    Bouzahzah, F.3    Ehrlich, B.E.4    Craft, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.