-
1
-
-
0025017688
-
Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation
-
Shlomchik, M., et al. 1990. Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation. J. Exp. Med. 171:265-292.
-
(1990)
J. Exp. Med.
, vol.171
, pp. 265-292
-
-
Shlomchik, M.1
-
2
-
-
0021940256
-
Treatment of murine lupus with monoclonal anti-T cell antibody
-
Wofsy, D., Ledbetter, J.A., Hendler, P.L., and Seaman, W.E. 1985. Treatment of murine lupus with monoclonal anti-T cell antibody. J. Immunol. 134:852-857.
-
(1985)
J. Immunol.
, vol.134
, pp. 852-857
-
-
Wofsy, D.1
Ledbetter, J.A.2
Hendler, P.L.3
Seaman, W.E.4
-
3
-
-
0028326095
-
Prevention of nephritis in major histocompatibility complex class II-deficient MRL-lpr mice
-
Jevnikar, A.M., Grusby, M.J., and Glimcher, L.H. 1994. Prevention of nephritis in major histocompatibility complex class II-deficient MRL-lpr mice. J. Exp. Med. 179:1137-1143.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 1137-1143
-
-
Jevnikar, A.M.1
Grusby, M.J.2
Glimcher, L.H.3
-
4
-
-
0018935423
-
Effects of thymectomy or androgen administration upon the autoimmune disease of MRL/Mp-lpr/lpr mice
-
Steinberg, A.D., Roths, J.B., Murphy, E.D., Steinberg, R.T., and Raveche, E.S. 1980. Effects of thymectomy or androgen administration upon the autoimmune disease of MRL/Mp-lpr/lpr mice. J. Immunol. 125:871-873.
-
(1980)
J. Immunol.
, vol.125
, pp. 871-873
-
-
Steinberg, A.D.1
Roths, J.B.2
Murphy, E.D.3
Steinberg, R.T.4
Raveche, E.S.5
-
5
-
-
0030589227
-
Induction of nonpathologic, humoral autoimmunity in lupus-prone mice by a class II-restricted, transgenic alpha beta T cell. Separation of autoantigen-specific and -nonspecific help
-
Peng, S.L., Fatenejad, S., and Craft, J. 1996. Induction of nonpathologic, humoral autoimmunity in lupus-prone mice by a class II-restricted, transgenic alpha beta T cell. Separation of autoantigen-specific and - nonspecific help. J. Immunol. 157:5225-5230.
-
(1996)
J. Immunol.
, vol.157
, pp. 5225-5230
-
-
Peng, S.L.1
Fatenejad, S.2
Craft, J.3
-
6
-
-
0025093055
-
Experimental induction of systemic lupus erythematosus by recognition of foreign Ia
-
Morris, S.C., Cohen, P.L., and Eisenberg, R.A. 1990. Experimental induction of systemic lupus erythematosus by recognition of foreign Ia. Clin. Immunol. Immunopathol. 57:263-273.
-
(1990)
Clin. Immunol. Immunopathol.
, vol.57
, pp. 263-273
-
-
Morris, S.C.1
Cohen, P.L.2
Eisenberg, R.A.3
-
7
-
-
0025138736
-
Autoantibodies in chronic graft versus host result from cognate T-B interactions
-
Morris, S.C., Cheek, R.L., Cohen, P.L., and Eisenberg, R.A. 1990. Autoantibodies in chronic graft versus host result from cognate T-B interactions. J. Exp. Med. 171:503-517.
-
(1990)
J. Exp. Med.
, vol.171
, pp. 503-517
-
-
Morris, S.C.1
Cheek, R.L.2
Cohen, P.L.3
Eisenberg, R.A.4
-
8
-
-
0037453010
-
Keratinocyte presentation of antigen directs autoimmune skin disease
-
Fan, L., Busser, B.W., Lifsted, T., Lo, D., and Laufer, T.M. 2003. Keratinocyte presentation of antigen directs autoimmune skin disease. Proc. Natl. Acad. Sci. U. S. A. 100:3386-3391.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 3386-3391
-
-
Fan, L.1
Busser, B.W.2
Lifsted, T.3
Lo, D.4
Laufer, T.M.5
-
9
-
-
0035920510
-
Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4(+)25(+) immunoregulatory T cells
-
Bensinger, S.J., Bandeira, A., Jordan, M.S., Caton, A.J., and Laufer, T.M. 2001. Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4(+)25(+) immunoregulatory T cells. J. Exp. Med. 194:427-438.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 427-438
-
-
Bensinger, S.J.1
Bandeira, A.2
Jordan, M.S.3
Caton, A.J.4
Laufer, T.M.5
-
10
-
-
0031437624
-
Following the fate of individual T cells throughout activation and clonal expansion. Signals from T cell receptor and CD28 differentially regulate the induction and duration of a proliferative response
-
Wells, A.D., Gudmundsdottir, H., and Turka, L.A. 1997. Following the fate of individual T cells throughout activation and clonal expansion. Signals from T cell receptor and CD28 differentially regulate the induction and duration of a proliferative response. J. Clin. Invest. 100:3173-3183.
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 3173-3183
-
-
Wells, A.D.1
Gudmundsdottir, H.2
Turka, L.A.3
-
11
-
-
0025011972
-
Subnucleosome structures as substrates in enzyme-linked immunosorbent assays
-
Burlingame, R.W., and Rubin, R.L. 1990. Subnucleosome structures as substrates in enzyme-linked immunosorbent assays. J. Immunol. Methods. 134:187-199.
-
(1990)
J. Immunol. Methods
, vol.134
, pp. 187-199
-
-
Burlingame, R.W.1
Rubin, R.L.2
-
12
-
-
0032520923
-
Genetic dissection of SLE pathogenesis. Sle1 on murine chromosome 1 leads to a selective loss of tolerance to H2A/H2B/DNA subnucleosomes
-
Mohan, C., Alas, E., Morel, L., Yang, P., and Wakeland, E.K. 1998. Genetic dissection of SLE pathogenesis. Sle1 on murine chromosome 1 leads to a selective loss of tolerance to H2A/H2B/DNA subnucleosomes. J. Clin. Invest. 101:1362-1372.
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 1362-1372
-
-
Mohan, C.1
Alas, E.2
Morel, L.3
Yang, P.4
Wakeland, E.K.5
-
13
-
-
0032743793
-
Genetic dissection of lupus pathogenesis: A recipe for nephrophilic autoantibodies
-
Mohan, C., et al. 1999. Genetic dissection of lupus pathogenesis: a recipe for nephrophilic autoantibodies. J. Clin. Invest. 103:1685-1695.
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 1685-1695
-
-
Mohan, C.1
-
14
-
-
0029835390
-
Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex
-
Laufer, T.M., DeKoning, J., Markowitz, J.S., Lo, D., and Glimcher, L.H. 1996. Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex. Nature. 383:81-85.
-
(1996)
Nature
, vol.383
, pp. 81-85
-
-
Laufer, T.M.1
DeKoning, J.2
Markowitz, J.S.3
Lo, D.4
Glimcher, L.H.5
-
15
-
-
0030060377
-
Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathway
-
Miyazaki, T., et al. 1996. Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathway. Cell. 84:531-541.
-
(1996)
Cell
, vol.84
, pp. 531-541
-
-
Miyazaki, T.1
-
16
-
-
0029945575
-
Antigen presentation and T cell development in H2-M-deficient mice
-
Fung-Leung, W.P., et al. 1996. Antigen presentation and T cell development in H2-M-deficient mice. Science. 271:1278-1281.
-
(1996)
Science
, vol.271
, pp. 1278-1281
-
-
Fung-Leung, W.P.1
-
17
-
-
0030048126
-
H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection
-
Martin, W.D., et al. 1996. H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection. Cell. 84:543-550.
-
(1996)
Cell
, vol.84
, pp. 543-550
-
-
Martin, W.D.1
-
18
-
-
0030698234
-
The imprint of intrathymic self-peptides on the mature T cell receptor repertoire
-
Sant'Angelo, D.B., et al. 1997. The imprint of intrathymic self-peptides on the mature T cell receptor repertoire. Immunity. 7:517-524.
-
(1997)
Immunity
, vol.7
, pp. 517-524
-
-
Sant'Angelo, D.B.1
-
19
-
-
0030848546
-
Deficient positive selection of CD4 T cells in mice displaying altered repertoires of MHC class II-bound self-peptides
-
Grubin, C.E., Kovats, S., deRoos, P., and Rudensky, A.Y. 1997. Deficient positive selection of CD4 T cells in mice displaying altered repertoires of MHC class II-bound self-peptides. Immunity. 7:197-208.
-
(1997)
Immunity
, vol.7
, pp. 197-208
-
-
Grubin, C.E.1
Kovats, S.2
DeRoos, P.3
Rudensky, A.Y.4
-
20
-
-
0033136289
-
Self-reactive T cells selected on thymic cortical epithelium are polyclonal and are pathogenic in vivo
-
Laufer, T.M., Fan, L., and Glimcher, L.H. 1999. Self-reactive T cells selected on thymic cortical epithelium are polyclonal and are pathogenic in vivo. J. Immunol. 162:5078-5084.
-
(1999)
J. Immunol.
, vol.162
, pp. 5078-5084
-
-
Laufer, T.M.1
Fan, L.2
Glimcher, L.H.3
-
21
-
-
0029553058
-
Immunoglobulin heavy chain gene replacement: A mechanism of receptor editing
-
Chen, C., Nagy, Z., Prak, E.L., and Weigert, M. 1995. Immunoglobulin heavy chain gene replacement: a mechanism of receptor editing. Immunity. 3:747-755.
-
(1995)
Immunity
, vol.3
, pp. 747-755
-
-
Chen, C.1
Nagy, Z.2
Prak, E.L.3
Weigert, M.4
-
22
-
-
0026029759
-
Ig H and L chain contributions to autoimmune specificities
-
Radic, M.Z., Mascelli, M.A., Erikson, J., Shan, H., and Weigert, M. 1991. Ig H and L chain contributions to autoimmune specificities. J. Immunol. 146:176-182.
-
(1991)
J. Immunol.
, vol.146
, pp. 176-182
-
-
Radic, M.Z.1
Mascelli, M.A.2
Erikson, J.3
Shan, H.4
Weigert, M.5
-
23
-
-
0037090275
-
Chronic graft-versus-host in Ig knockin transgenic mice abrogates B cell tolerance in anti-double-stranded DNA B cells
-
Sekiguchi, D.R., et al. 2002. Chronic graft-versus-host in Ig knockin transgenic mice abrogates B cell tolerance in anti-double-stranded DNA B cells. J. Immunol. 168:4142-4153.
-
(2002)
J. Immunol.
, vol.168
, pp. 4142-4153
-
-
Sekiguchi, D.R.1
-
24
-
-
0030827382
-
Regulation of anti-double-stranded DNA B cells in nonautoimmune mice: Localization to the T-B interface of the splenic follicle
-
Mandik-Nayak, L., Bui, A., Noorchashm, H., Eaton, A., and Erikson, J. 1997. Regulation of anti-double-stranded DNA B cells in nonautoimmune mice: localization to the T-B interface of the splenic follicle. J. Exp. Med. 186:1257-1267.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1257-1267
-
-
Mandik-Nayak, L.1
Bui, A.2
Noorchashm, H.3
Eaton, A.4
Erikson, J.5
-
25
-
-
0033532630
-
MRL-lpr/lpr mice exhibit a defect in maintaining developmental arrest and follicular exclusion of anti-double-stranded DNA B cells
-
Mandik-Nayak, L., et al. 1999. MRL-lpr/lpr mice exhibit a defect in maintaining developmental arrest and follicular exclusion of anti-double-stranded DNA B cells. J. Exp. Med. 189:1799-1814.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1799-1814
-
-
Mandik-Nayak, L.1
-
26
-
-
18344369175
-
The impact of T helper and T regulatory cells on the regulation of anti-double-stranded DNA B cells
-
Seo, S.J., et al. 2002. The impact of T helper and T regulatory cells on the regulation of anti-double-stranded DNA B cells. Immunity. 16:535-546.
-
(2002)
Immunity
, vol.16
, pp. 535-546
-
-
Seo, S.J.1
-
27
-
-
0027245507
-
Genesis and evolution of antichromatin autoantibodies in murine lupus implicates T-dependent immunization with self antigen
-
Burlingame, R.W., Rubin, R.L., Balderas, R.S., and Theofilopoulos, A.N. 1993. Genesis and evolution of antichromatin autoantibodies in murine lupus implicates T-dependent immunization with self antigen. J. Clin. Invest. 91:1687-1696.
-
(1993)
J. Clin. Invest.
, vol.91
, pp. 1687-1696
-
-
Burlingame, R.W.1
Rubin, R.L.2
Balderas, R.S.3
Theofilopoulos, A.N.4
-
28
-
-
0028789148
-
Anatomy of autoantibody production: Dominant localization of antibody-producing cells to T cell zones in Fas-deficient mice
-
Jacobson, B.A., et al. 1995. Anatomy of autoantibody production: dominant localization of antibody-producing cells to T cell zones in Fas-deficient mice. Immunity. 3:509-519.
-
(1995)
Immunity
, vol.3
, pp. 509-519
-
-
Jacobson, B.A.1
-
29
-
-
0032479526
-
Visualization of specific B and T lymphocyte interactions in the lymph node
-
Garside, P., et al. 1998. Visualization of specific B and T lymphocyte interactions in the lymph node. Science. 281:96-99.
-
(1998)
Science
, vol.281
, pp. 96-99
-
-
Garside, P.1
-
30
-
-
0029813549
-
Sequential antigen-specific growth of T cells in the T zones and follicles in response to pigeon cytochrome c
-
Gulbranson-Judge, A., and MacLennan, I. 1996. Sequential antigen-specific growth of T cells in the T zones and follicles in response to pigeon cytochrome c. Eur. J. Immunol. 26:1830-1837.
-
(1996)
Eur. J. Immunol.
, vol.26
, pp. 1830-1837
-
-
Gulbranson-Judge, A.1
MacLennan, I.2
-
31
-
-
0030459799
-
Costimulation and autoimmunity
-
Tivol, E.A., Schweitzer, A.N., and Sharpe, A.H. 1996. Costimulation and autoimmunity. Curr. Opin. Immunol. 8:822-830.
-
(1996)
Curr. Opin. Immunol.
, vol.8
, pp. 822-830
-
-
Tivol, E.A.1
Schweitzer, A.N.2
Sharpe, A.H.3
-
32
-
-
0035936797
-
The TNF and TNF receptor superfamilies: Integrating mammalian biology
-
Locksley, R.M., Killeen, N., and Lenardo, M.J. 2001. The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell. 104:487-501.
-
(2001)
Cell
, vol.104
, pp. 487-501
-
-
Locksley, R.M.1
Killeen, N.2
Lenardo, M.J.3
-
33
-
-
0032753621
-
Compromised OX40 function in CD28-deficient mice is linked with failure to develop CXC chemokine receptor 5-positive CD4 cells and germinal centers
-
Walker, L.S., et al. 1999. Compromised OX40 function in CD28-deficient mice is linked with failure to develop CXC chemokine receptor 5-positive CD4 cells and germinal centers. J. Exp. Med. 190:1115-1122.
-
(1999)
J. Exp. Med.
, vol.190
, pp. 1115-1122
-
-
Walker, L.S.1
-
34
-
-
0029938992
-
The T cell-B cell interaction via OX40-OX40L is necessary for the T cell-dependent humoral immune response
-
Stuber, E., and Strober, W. 1996. The T cell-B cell interaction via OX40-OX40L is necessary for the T cell-dependent humoral immune response. J. Exp. Med. 183:979-989.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 979-989
-
-
Stuber, E.1
Strober, W.2
-
35
-
-
0035804269
-
ICOS is essential for effective T-helper-cell responses
-
Tafuri, A., et al. 2001. ICOS is essential for effective T-helper-cell responses. Nature. 409:105-109.
-
(2001)
Nature
, vol.409
, pp. 105-109
-
-
Tafuri, A.1
-
36
-
-
0035804268
-
ICOS is critical for CD40-mediated antibody class switching
-
McAdam, A.J., et al. 2001. ICOS is critical for CD40-mediated antibody class switching. Nature. 409:102-105.
-
(2001)
Nature
, vol.409
, pp. 102-105
-
-
McAdam, A.J.1
-
37
-
-
0035804254
-
ICOS co-stimulatory receptor is essential for T-cell activation and function
-
Dong, C., et al. 2001. ICOS co-stimulatory receptor is essential for T-cell activation and function. Nature. 409:97-101.
-
(2001)
Nature
, vol.409
, pp. 97-101
-
-
Dong, C.1
-
38
-
-
0030936275
-
B7-1 and B7-2 have overlapping, critical roles in immunoglobulin class switching and germinal center formation
-
Borriello, F., et al. 1997. B7-1 and B7-2 have overlapping, critical roles in immunoglobulin class switching and germinal center formation. Immunity. 6:303-313.
-
(1997)
Immunity
, vol.6
, pp. 303-313
-
-
Borriello, F.1
-
39
-
-
0029052398
-
Cellular interaction in germinal centers. Roles of CD40 ligand and B7-2 in established germinal centers
-
Han, S., et al. 1995. Cellular interaction in germinal centers. Roles of CD40 ligand and B7-2 in established germinal centers. J. Immunol. 155:556-567.
-
(1995)
J. Immunol.
, vol.155
, pp. 556-567
-
-
Han, S.1
-
40
-
-
0030959102
-
Requirement of CD28-CD86 co-stimulation in the interaction between antigen-primed T helper type 2 and B cells
-
Nakajima, A., et al. 1997. Requirement of CD28-CD86 co-stimulation in the interaction between antigen-primed T helper type 2 and B cells. Int. Immunol. 9:637-644.
-
(1997)
Int. Immunol.
, vol.9
, pp. 637-644
-
-
Nakajima, A.1
-
41
-
-
0028834366
-
Preferential dependence of autoantibody production in murine lupus on CD86 costimulatory molecule
-
Nakajima, A., et al. 1995. Preferential dependence of autoantibody production in murine lupus on CD86 costimulatory molecule. Eur. J. Immunol. 25:3060-3069.
-
(1995)
Eur. J. Immunol.
, vol.25
, pp. 3060-3069
-
-
Nakajima, A.1
-
42
-
-
0029862687
-
B cells solicit their own help from T cells
-
Stockinger, B., Zal, T., Zal, A., and Gray, D. 1996. B cells solicit their own help from T cells. J. Exp. Med 183:891-899.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 891-899
-
-
Stockinger, B.1
Zal, T.2
Zal, A.3
Gray, D.4
-
43
-
-
0035253592
-
A receptor presentation hypothesis for T cell help that recruits autoreactive B cells
-
Zhang, X., Smith, D.S., Guth, A., and Wysocki, L.J. 2001. A receptor presentation hypothesis for T cell help that recruits autoreactive B cells. J. Immunol. 166:1562-1571.
-
(2001)
J. Immunol.
, vol.166
, pp. 1562-1571
-
-
Zhang, X.1
Smith, D.S.2
Guth, A.3
Wysocki, L.J.4
-
44
-
-
0030890285
-
T cells specific for DNA-binding peptides
-
Wang, M., Desai, D., and Marion, T.N. 1997. T cells specific for DNA-binding peptides. Lupus. 6:349-350.
-
(1997)
Lupus
, vol.6
, pp. 349-350
-
-
Wang, M.1
Desai, D.2
Marion, T.N.3
-
45
-
-
0027529397
-
A peptide derived from an autoantibody can stimulate T cells in the (NZB x NZW) F1 mouse model of systemic lupus erythematosus
-
Ebling, F.M., Tsao, B.P., Singh, R.R., Sercarz, E., and Hahn, B.H. 1993. A peptide derived from an autoantibody can stimulate T cells in the (NZB x NZW) F1 mouse model of systemic lupus erythematosus. Arthritis. Rheum. 36:355-364.
-
(1993)
Arthritis. Rheum.
, vol.36
, pp. 355-364
-
-
Ebling, F.M.1
Tsao, B.P.2
Singh, R.R.3
Sercarz, E.4
Hahn, B.H.5
-
46
-
-
0029069499
-
T cell determinants from autoantibodies to DNA can upregulate autoimmunity in murine systemic lupus erythematosus
-
Singh, R.R., et al. 1995. T cell determinants from autoantibodies to DNA can upregulate autoimmunity in murine systemic lupus erythematosus. J. Exp. Med. 181:2017-2027.
-
(1995)
J. Exp. Med.
, vol.181
, pp. 2017-2027
-
-
Singh, R.R.1
-
47
-
-
0027477318
-
Nucleosome: A major immunogen for pathogenic autoantibody-inducing T cells of lupus
-
Mohan, C., Adams, S., Stanik, V., and Datta, S.K. 1993. Nucleosome: a major immunogen for pathogenic autoantibody-inducing T cells of lupus. J. Exp. Med. 177:1367-1381.
-
(1993)
J. Exp. Med.
, vol.177
, pp. 1367-1381
-
-
Mohan, C.1
Adams, S.2
Stanik, V.3
Datta, S.K.4
-
48
-
-
0035884989
-
Terminal deoxynucleotidyl transferase deficiency decreases autoimmune disease in MRL-Fas(lpr) mice
-
Feeney, A.J., Lawson, B.R., Kono, D.H., and Theofilopoulos, A.N. 2001. Terminal deoxynucleotidyl transferase deficiency decreases autoimmune disease in MRL-Fas(lpr) mice. J. Immunol. 167:3486-3493.
-
(2001)
J. Immunol.
, vol.167
, pp. 3486-3493
-
-
Feeney, A.J.1
Lawson, B.R.2
Kono, D.H.3
Theofilopoulos, A.N.4
-
49
-
-
0036481263
-
Epitope spreading in immune-mediated diseases: Implications for immunotherapy
-
Vanderlugt, C.L., and Miller, S.D. 2002. Epitope spreading in immune-mediated diseases: implications for immunotherapy. Nat. Rev. Immunol. 2:85-95.
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 85-95
-
-
Vanderlugt, C.L.1
Miller, S.D.2
-
50
-
-
0035525528
-
From T to B and back again: Positive feedback in systemic autoimmune disease
-
Shlomchik, M.J., Craft, J.E., and Mamula, M.J. 2001. From T to B and back again: positive feedback in systemic autoimmune disease. Nat. Rev. Immunol. 1:147-153.
-
(2001)
Nat. Rev. Immunol.
, vol.1
, pp. 147-153
-
-
Shlomchik, M.J.1
Craft, J.E.2
Mamula, M.J.3
-
51
-
-
0031179651
-
Genetic dissection of systemic lupus erythematosus pathogenesis: Sle2 on murine chromosome 4 leads to B cell hyperactivity
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Mohan, C., Morel, L., Yang, P., and Wakeland, E.K. 1997. Genetic dissection of systemic lupus erythematosus pathogenesis: Sle2 on murine chromosome 4 leads to B cell hyperactivity. J. Immunol. 159:454-465.
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(1997)
J. Immunol.
, vol.159
, pp. 454-465
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Mohan, C.1
Morel, L.2
Yang, P.3
Wakeland, E.K.4
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