Deficiency in CD22, a B cell-specific inhibitory receptor, is sufficient to predispose to development of high affinity autoantibodies

Journal of Experimental Medicine

Volumn 189, Issue 8, 1999, Pages 1307-1313

  O'Keefe, Theresa L ^a   Williams, Gareth T ^a   Batista, Facundo D ^a   Neuberger, Michael S ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

Autoimmunity; B lymphocyte; CD22; Inhibitory receptor; Threshold

Indexed keywords

AUTOANTIBODY; CD22 ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ANTIBODY TITER; ARTICLE; AUTOIMMUNITY; B LYMPHOCYTE; CONTROLLED STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

AGE FACTORS; AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, CD22; ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE; AUTOANTIBODIES; AUTOIMMUNITY; B-LYMPHOCYTES; BIOSENSING TECHNIQUES; CELL ADHESION MOLECULES; DNA; GENE TARGETING; IMMUNOGLOBULIN G; IMMUNOGLOBULIN VARIABLE REGION; KINETICS; LECTINS; MICE; MICE, INBRED STRAINS; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; RECEPTORS, CELL SURFACE;

EID: 0033583479     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.189.8.1307     Document Type: Article

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