메뉴 건너뛰기




Volumn 19, Issue 2-3, 1999, Pages 245-257

Autoreactive T cells in murine lupus: Origins ond roles in autoantibody production

Author keywords

Autoantibodies; Autoimmunity; Lupus; Mouse models; MRL mice; T lymphocytes

Indexed keywords

AUTOANTIBODY; AUTOANTIGEN;

EID: 0032797012     PISSN: 0257277X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02786492     Document Type: Review
Times cited : (28)

References (85)
  • 1
    • 0024518559 scopus 로고
    • Antinuclear antibodies: Diagnostic markers for autoimmune diseases and probes for cell biology
    • Tan EM: Antinuclear antibodies: Diagnostic markers for autoimmune diseases and probes for cell biology. Adv Immunol 1989;44:93-151.
    • (1989) Adv Immunol , vol.44 , pp. 93-151
    • Tan, E.M.1
  • 2
    • 0022273898 scopus 로고
    • Murine models of systemic lupus erythematosus
    • Theofilopoulos AN, Dixon FJ: Murine models of systemic lupus erythematosus. Adv Immunol 1985;37:269-390.
    • (1985) Adv Immunol , vol.37 , pp. 269-390
    • Theofilopoulos, A.N.1    Dixon, F.J.2
  • 3
    • 0017891320 scopus 로고
    • Presence of anti-Sm reactivity in autoimmune mouse strains
    • Eisenberg RA, Tan EM, Dixon FJ: Presence of anti-Sm reactivity in autoimmune mouse strains. J Exp Med 1978;147:582-587.
    • (1978) J Exp Med , vol.147 , pp. 582-587
    • Eisenberg, R.A.1    Tan, E.M.2    Dixon, F.J.3
  • 4
    • 0022825518 scopus 로고
    • Glomerular lesions in MRL mice. A light and immunofluorescence microscopic study
    • Hewicker M, Trautwein G: Glomerular lesions in MRL mice. A light and immunofluorescence microscopic study. Zentralblatt für Veterinarmedizin Reihe B 1986;33:727-739.
    • (1986) Zentralblatt für Veterinarmedizin Reihe B , vol.33 , pp. 727-739
    • Hewicker, M.1    Trautwein, G.2
  • 5
    • 0027245507 scopus 로고
    • Genesis and evolution of antichromatin autoantibodies in murine lupus implicates T-dependent immunization with self antigen
    • Burlingame RW, Rubin RL, Balderas RS, Theofilopoulos AN: Genesis and evolution of antichromatin autoantibodies in murine lupus implicates T-dependent immunization with self antigen. J Clin Invest 1993;91:1687-1696.
    • (1993) J Clin Invest , vol.91 , pp. 1687-1696
    • Burlingame, R.W.1    Rubin, R.L.2    Balderas, R.S.3    Theofilopoulos, A.N.4
  • 6
    • 0028302604 scopus 로고
    • Pattern of anti-small nuclear ribonucleoprotein antibodies in MRL/Mp-lpr/lpr mice suggests that the intact U1 snRNP particle is their autoimmunogenic target
    • Fatenejad S, Brooks W, Schwartz A, Craft J: Pattern of anti-small nuclear ribonucleoprotein antibodies in MRL/Mp-lpr/lpr mice suggests that the intact U1 snRNP particle is their autoimmuno genic target. J Immunol 1994;152;5523-5531.
    • (1994) J Immunol , vol.152 , pp. 5523-5531
    • Fatenejad, S.1    Brooks, W.2    Schwartz, A.3    Craft, J.4
  • 7
    • 0028129894 scopus 로고
    • Effects of the lpr mutation on elimination and inactivation of self-reactive B cells
    • Rathmell JC, Goodnow CC: Effects of the lpr mutation on elimination and inactivation of self-reactive B cells. J Immunol 1994;153:2831-2842.
    • (1994) J Immunol , vol.153 , pp. 2831-2842
    • Rathmell, J.C.1    Goodnow, C.C.2
  • 8
    • 0028485743 scopus 로고
    • The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice
    • Singer GG, Abbas AK: The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice. Immunity 1994;1:365-371.
    • (1994) Immunity , vol.1 , pp. 365-371
    • Singer, G.G.1    Abbas, A.K.2
  • 9
    • 0029939945 scopus 로고    scopus 로고
    • The roles of costimulation and fas in T cell apoptosis and peripheral tolerance
    • Van Parijs L, Ibraghimov A, Abbas AK: The roles of costimulation and fas in T cell apoptosis and peripheral tolerance. Immunity 1996;4:321-328.
    • (1996) Immunity , vol.4 , pp. 321-328
    • Van Parijs, L.1    Ibraghimov, A.2    Abbas, A.K.3
  • 10
    • 0021173447 scopus 로고
    • Induction of various autoantibodies by mutant gene lpr in several strains of mice
    • Izui S, Kelley VE, Masuda K, Yoshida H, Roths JB, Murphy ED: Induction of various autoantibodies by mutant gene lpr in several strains of mice. J Immunol 1984;133:227-233.
    • (1984) J Immunol , vol.133 , pp. 227-233
    • Izui, S.1    Kelley, V.E.2    Masuda, K.3    Yoshida, H.4    Roths, J.B.5    Murphy, E.D.6
  • 11
    • 0030856589 scopus 로고    scopus 로고
    • The regulation of murine lupus
    • Peng SL, Craft J: The regulation of murine lupus. Ann NY Acad Sci 1997;815:128-138.
    • (1997) Ann NY Acad Sci , vol.815 , pp. 128-138
    • Peng, S.L.1    Craft, J.2
  • 12
    • 0030931614 scopus 로고    scopus 로고
    • Self antigens and epitope spreading in systemic autoimmunity
    • Craft J, Fatenejad S: Self antigens and epitope spreading in systemic autoimmunity. Arthritis Rheum 1997;40:1374-1382.
    • (1997) Arthritis Rheum , vol.40 , pp. 1374-1382
    • Craft, J.1    Fatenejad, S.2
  • 13
    • 0022573806 scopus 로고
    • The lupus autoantigens and the pathogenesis of systemic lupus erythematosus
    • Hardin JA:The lupus autoantigens and the pathogenesis of systemic lupus erythematosus. Arthritis Rheum 1986;29:457-460.
    • (1986) Arthritis Rheum , vol.29 , pp. 457-460
    • Hardin, J.A.1
  • 15
    • 0023718496 scopus 로고
    • V region sequences of anti-DNA and anti-RNA autoantibodies from NZB/NZW F1 mice
    • Eilat D, Webster DM, Rees AR: V region sequences of anti-DNA and anti-RNA autoantibodies from NZB/NZW F1 mice. J Immunol 1988;141:1745-1743.
    • (1988) J Immunol , vol.141 , pp. 1745-1743
    • Eilat, D.1    Webster, D.M.2    Rees, A.R.3
  • 17
    • 0025054661 scopus 로고
    • Interclonal and intraclonal diversity among anti-DNA antibodies from an (NZB × NZW)F1 mouse
    • Marion TN, Tillman DM, Jou N: Interclonal and intraclonal diversity among anti-DNA antibodies from an (NZB × NZW)F1 mouse. J Immunol 1990;145:2322-2332.
    • (1990) J Immunol , vol.145 , pp. 2322-2332
    • Marion, T.N.1    Tillman, D.M.2    Jou, N.3
  • 18
    • 0025334066 scopus 로고
    • V region sequences of an idiotypically connected family of pathogenic anti-DNA autoantibodies
    • O'Keefe TL, Bandyopadhyay S, Datta SK, Imanishi-Kari T:Vregion sequences of an idiotypically con nected family of pathogenic anti-DNA autoantibodies. J Immunol 1990;144:4275-4283.
    • (1990) J Immunol , vol.144 , pp. 4275-4283
    • O'Keefe, T.L.1    Bandyopadhyay, S.2    Datta, S.K.3    Imanishi-Kari, T.4
  • 19
    • 0025325145 scopus 로고
    • Molecular characterization of a somatically mutated anti-DNA antibody bearing two SLE related idiotypes
    • Davidson A, Mannheimer-Lory A, Aranow C, Peterson R, Hannigan N, Diamond B: Molecular characterization of a somatically mutated anti-DNA antibody bearing two SLE related idiotypes. J Clin Invest 1990;85:1401-1409.
    • (1990) J Clin Invest , vol.85 , pp. 1401-1409
    • Davidson, A.1    Mannheimer-Lory, A.2    Aranow, C.3    Peterson, R.4    Hannigan, N.5    Diamond, B.6
  • 21
    • 0028292951 scopus 로고
    • Genetic and structural evidence for antigen selection of anti-DNA anti bodies
    • Radic MZ, Weigert M: Genetic and structural evidence for antigen selection of anti-DNA anti bodies. Annu Rev Immunol 1994;12:487-520.
    • (1994) Annu Rev Immunol , vol.12 , pp. 487-520
    • Radic, M.Z.1    Weigert, M.2
  • 22
    • 0018935423 scopus 로고
    • Effects of thymectomy or androgen administration upon the autoimmune disease of MRL/Mp-lpr/lpr mice
    • Steinberg AD, Roths JB, Murphy ED, Steinberg RT, Raveche ES: Effects of thymectomy or androgen administration upon the autoimmune disease of MRL/Mp-lpr/lpr mice. J Immunol 1980;125:871-873.
    • (1980) J Immunol , vol.125 , pp. 871-873
    • Steinberg, A.D.1    Roths, J.B.2    Murphy, E.D.3    Steinberg, R.T.4    Raveche, E.S.5
  • 24
    • 0023896085 scopus 로고
    • The contribution of L3T4+ T cells to lymphoproliferation and autoantibody production in MRL-lpr/lpr mice
    • Santoro TJ, Portanova JP, Kotzin BL: The contribution of L3T4+ T cells to lymphoproliferation and autoantibody production in MRL-lpr/lpr mice. J Exp Med 1988;167:1713-1718.
    • (1988) J Exp Med , vol.167 , pp. 1713-1718
    • Santoro, T.J.1    Portanova, J.P.2    Kotzin, B.L.3
  • 25
    • 0027231554 scopus 로고
    • lpr T cells are necessary for autoantibody production in lpr mice
    • Sobel ES, Cohen PL, Eisenberg RA: lpr T cells are necessary for autoantibody production in lpr mice. J Immunol 1993;150:4160-4167.
    • (1993) J Immunol , vol.150 , pp. 4160-4167
    • Sobel, E.S.1    Cohen, P.L.2    Eisenberg, R.A.3
  • 26
    • 0026613009 scopus 로고
    • Lymphoid development in mice congenitally lacking T cell receptor alpha beta-expressing cells
    • Philpott KL, Viney JL, Kay G, Rastan S, Gardiner EM, Chae S, et al.: Lymphoid development in mice congenitally lacking T cell receptor alpha beta-expressing cells. Science 1992;256:1448-1452.
    • (1992) Science , vol.256 , pp. 1448-1452
    • Philpott, K.L.1    Viney, J.L.2    Kay, G.3    Rastan, S.4    Gardiner, E.M.5    Chae, S.6
  • 28
    • 0028326095 scopus 로고
    • Prevention of nephritis in major histocompatibility complex class II-deficient MRL-lpr mice
    • Jevnikar AM, Grusby MJ, Glimcher LH: Prevention of nephritis in major histocompatibility complex class II-deficient MRL-lpr mice. J Exp Med 1994;179:1137-1143.
    • (1994) J Exp Med , vol.179 , pp. 1137-1143
    • Jevnikar, A.M.1    Grusby, M.J.2    Glimcher, L.H.3
  • 30
    • 0028268517 scopus 로고
    • Chronic treatment of C3H-lpr/lpr and C3H-gld/gld mice with anti-CD8 monoclonal antibody prevent the accumulation of double negative T cells but not autoantibody production
    • Giese T, Davidson WF: Chronic treatment of C3H-lpr/lpr and C3H-gId/gId mice with anti-CD8 monoclonal antibody prevent the accumulation of double negative T cells but not autoantibody production. J Immunol 1994;152:2000.
    • (1994) J Immunol , vol.152 , pp. 2000
    • Giese, T.1    Davidson, W.F.2
  • 31
    • 0029070099 scopus 로고
    • CD8+ T cell-deficient lpr/lpr mice, CD4+ B220+ and CD4+B220. T cells replace B220+double-negative T cells as the predominant populations in enlarged lymph nodes
    • Giese T, Davidson WF: CD8+ T cell-deficient lpr/lpr mice, CD4+ B220+ and CD4+B220. T cells replace B220+double-negative T cells as the predominant populations in enlarged lymph nodes. J Immunol 1995;154: 4986-4995.
    • (1995) J Immunol , vol.154 , pp. 4986-4995
    • Giese, T.1    Davidson, W.F.2
  • 32
    • 0028898599 scopus 로고
    • Greatly reduced lymphoproliferation in lpr mice lacking major histocompatibility complex class I
    • Maldonado MA, Eisenberg RA, Roper E, Cohen PL, Kotzin BL: Greatly reduced lymphoproliferation in lpr mice lacking major histocompatibility complex class I J Exp Med 1995;181:641-648.
    • (1995) J Exp Med , vol.181 , pp. 641-648
    • Maldonado, M.A.1    Eisenberg, R.A.2    Roper, E.3    Cohen, P.L.4    Kotzin, B.L.5
  • 34
    • 0028985378 scopus 로고
    • + T cells but normal autoantibody production in lpr/lpr mice lacking major histocompatibility complex class I molecules
    • + T cells but normal autoantibody production in lpr/lpr mice lacking major histocompatibility complex class I molecules. Eur J Immunol 1995;25:37-41.
    • (1995) Eur J Immunol , vol.25 , pp. 37-41
    • Ohteki, T.1    Iwamoto, M.2    Izui, S.3    MacDonald, H.R.4
  • 35
    • 0026343952 scopus 로고
    • Junctional region sequences of T-cell receptor beta-chain genes expressed by pathogenic anti-DNA autoantibody-inducing helper T cells from lupus mice: Possible selection by cationic autoantigens
    • Adams S, Leblanc P, Datta SK: Junctional region sequences of T-cell receptor beta-chain genes expressed by pathogenic anti-DNA autoantibody-inducing helper T cells from lupus mice: possible selection by cationic autoantigens. PNAS 1991;88:11,271-11,275.
    • (1991) PNAS , vol.88 , pp. 11271-11275
    • Adams, S.1    Leblanc, P.2    Datta, S.K.3
  • 36
    • 0027477318 scopus 로고
    • Nucleosome: A major immunogen for pathogenic autoantibody-inducing T cells of lupus
    • Mohan C, Adams S, Stanik V, Datta SK: Nucleosome: a major immunogen for pathogenic autoantibody-inducing T cells of lupus. J Exp Med 1993;177:1367-1381.
    • (1993) J Exp Med , vol.177 , pp. 1367-1381
    • Mohan, C.1    Adams, S.2    Stanik, V.3    Datta, S.K.4
  • 37
    • 0029953857 scopus 로고    scopus 로고
    • Nucleosomal peptide epitopes for nephritis-inducing T helper cells of murine lupus
    • Kaliyaperumal A, Mohan C, Wu W, Datta SK: Nucleosomal peptide epitopes for nephritis-inducing T helper cells of murine lupus. J Exp Med 1996;183:2459-2469.
    • (1996) J Exp Med , vol.183 , pp. 2459-2469
    • Kaliyaperumal, A.1    Mohan, C.2    Wu, W.3    Datta, S.K.4
  • 39
    • 0029939451 scopus 로고    scopus 로고
    • Autoimmune lpr/lpr mice deficient in CD40 ligand: Spontaneous immunoglobulin class switching with dichotomy of autoantibody responses
    • Ma J, Xu J, Peng Q, Zhang J, Grewal IS, Flavell RA, Craft J: Autoimmune lpr/lpr mice deficient in CD40 ligand: spontaneous immunoglobulin class switching with dichotomy of autoantibody responses. J Immunol 1996;157:417-426.
    • (1996) J Immunol , vol.157 , pp. 417-426
    • Ma, J.1    Xu, J.2    Peng, Q.3    Zhang, J.4    Grewal, I.S.5    Flavell, R.A.6    Craft, J.7
  • 40
    • 0028483990 scopus 로고
    • Treatment of murine lupus with CTLA4Ig
    • Finck BK, Linsley PS, Wofsy D: Treatment of murine lupus with CTLA4Ig. Science 1994;265:1225-1227.
    • (1994) Science , vol.265 , pp. 1225-1227
    • Finck, B.K.1    Linsley, P.S.2    Wofsy, D.3
  • 41
    • 0028852328 scopus 로고
    • Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis
    • Mohan C, Shi Y, Laman JD, Datta SK: Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis. J Immunol 1995;154:1470-1480.
    • (1995) J Immunol , vol.154 , pp. 1470-1480
    • Mohan, C.1    Shi, Y.2    Laman, J.D.3    Datta, S.K.4
  • 42
    • 0024444304 scopus 로고
    • Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor
    • Kaye J, Hsu ML, Sauron ME, Jameson SC, Gascoigne NR, Hedrick SM: Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor. Nature 1989;341:746-749.
    • (1989) Nature , vol.341 , pp. 746-749
    • Kaye, J.1    Hsu, M.L.2    Sauron, M.E.3    Jameson, S.C.4    Gascoigne, N.R.5    Hedrick, S.M.6
  • 43
    • 0030589227 scopus 로고    scopus 로고
    • Induction of non-pathologic, humoral autoimmunity in lupus-prone mice by a class II-restricted, transgenic αβ T cell: Separation of autoantigen-specific and -nonspecific help
    • Peng SL, Patenejad S, Craft J: Induction of non-pathologic, humoral autoimmunity in lupus-prone mice by a class II-restricted, transgenic αβ T cell: separation of autoantigen-specific and -nonspecific help. J Immunol 1996;157:5225-5230.
    • (1996) J Immunol , vol.157 , pp. 5225-5230
    • Peng, S.L.1    Patenejad, S.2    Craft, J.3
  • 44
    • 0029913381 scopus 로고    scopus 로고
    • Hyperexpression of CD40 ligand by B and T cells in human lupus and its role in pathogenic autoantibody production
    • Desai-Mehta A, Lu L, Ramsey GR, Datta SK: Hyperexpression of CD40 ligand by B and T cells in human lupus and its role in pathogenic autoantibody production. J Clin Invest 1996;97:2063-2073.
    • (1996) J Clin Invest , vol.97 , pp. 2063-2073
    • Desai-Mehta, A.1    Lu, L.2    Ramsey, G.R.3    Datta, S.K.4
  • 45
    • 0028798616 scopus 로고
    • Structure and specificity of T cell receptors expressed by potentially pathogenic anti-DNA autoantibody-inducing T cells in human lupus
    • Desai-Mehta A, Mao C, Rajagopalan S, Robinson T, Datta SK; Structure and specificity of T cell receptors expressedby potentially pathogenic anti-DNA autoantibody-inducing T cells in human lupus. J Clin Invest 1995;95:531-541.
    • (1995) J Clin Invest , vol.95 , pp. 531-541
    • Desai-Mehta, A.1    Mao, C.2    Rajagopalan, S.3    Robinson, T.4    Datta, S.K.5
  • 46
    • 0029862164 scopus 로고    scopus 로고
    • Increased expression of CD40 ligand on systemic lupus erythematosus lymphocytes
    • Koshy M, Berger D, Crow MK: Increased expression of CD40 ligand on systemic lupus erythematosus lymphocytes. J Clin Invest 1996;98:826-837.
    • (1996) J Clin Invest , vol.98 , pp. 826-837
    • Koshy, M.1    Berger, D.2    Crow, M.K.3
  • 47
    • 0027433523 scopus 로고
    • Human T cell clones reactive against U-small nuclear ribonucleoprotein autoantigens from connective tissue disease patients and healthy individuals
    • Hoffman RW, Takeda Y, Sharp GC, Lee DR, Hill DL, Kaneoka H, et al.: Human T cell clones reactive against U-small nuclear ribonucleoprotein autoantigens from connective tissue disease patients and healthy individuals. J Immunol 1993;151:6460.
    • (1993) J Immunol , vol.151 , pp. 6460
    • Hoffman, R.W.1    Takeda, Y.2    Sharp, G.C.3    Lee, D.R.4    Hill, D.L.5    Kaneoka, H.6
  • 48
    • 0027179046 scopus 로고
    • Detection and epitope analysis of autoantigen-reactive T cells to the U1-small nuclear ribonucleoprotein A protein in autoimmune disease patients
    • Okubo M, Yamamoto K, Kato T, Matsuuraa N, Nishimaki T, Kasukawa R, et al.: Detection and epitope analysis of autoantigen-reactive T cells to the U1-small nuclear ribonucleoprotein A protein in autoimmune disease patients. J Immunol 1993;151:1108-1115.
    • (1993) J Immunol , vol.151 , pp. 1108-1115
    • Okubo, M.1    Yamamoto, K.2    Kato, T.3    Matsuuraa, N.4    Nishimaki, T.5    Kasukawa, R.6
  • 49
    • 0021909121 scopus 로고
    • Subclass restriction and polyclonality of the systemic lupus erythematosus marker antibody anti-Sm
    • Eisenberg R, Dyer K, Craven SY, Fuller CR, Yount W: Subclass restriction and polyclonality of the systemic lupus erythematosus marker antibody anti-Sm. J Clin Invest 1985;75:1270.
    • (1985) J Clin Invest , vol.75 , pp. 1270
    • Eisenberg, R.1    Dyer, K.2    Craven, S.Y.3    Fuller, C.R.4    Yount, W.5
  • 50
    • 0028229905 scopus 로고
    • Autoantigen-specific T cell proliferation induced by the ribosomal P2 protein in patients with systemic lupus erythematosus
    • Crow MK, DelGiudice-Asch G, Zehetbauer JB, Lawson JL, Brot N, Weissbach H, et al.: Autoantigen-specific T cell proliferation induced by the ribosomal P2 protein in patients with systemic lupus erythematosus. J Clin Invest 1994;94:345.
    • (1994) J Clin Invest , vol.94 , pp. 345
    • Crow, M.K.1    DelGiudice-Asch, G.2    Zehetbauer, J.B.3    Lawson, J.L.4    Brot, N.5    Weissbach, H.6
  • 51
    • 0026671268 scopus 로고
    • Defective maintenance of T cell tolerance to a superantigen in MRL-lpr/lpr mice
    • Zhou T, Bluethmann H, Zhang J, Edwards CK III, Mountz JD: Defective maintenance of T cell tolerance to a superantigen in MRL-lpr/lpr mice. J Exp Med 1992;176:1063-1072.
    • (1992) J Exp Med , vol.176 , pp. 1063-1072
    • Zhou, T.1    Bluethmann, H.2    Zhang, J.3    Edwards C.K. III4    Mountz, J.D.5
  • 52
    • 0027266844 scopus 로고
    • Studies of T cell deletion and T cell anergy following in vivo administration of SEB to normal and lupus-prone mice
    • Scott DE, Kisch WJ, Steinberg AD: Studies of T cell deletion and T cell anergy following in vivo administration of SEB to normal and lupus-prone mice. J Immunol 1993;150:664-672.
    • (1993) J Immunol , vol.150 , pp. 664-672
    • Scott, D.E.1    Kisch, W.J.2    Steinberg, A.D.3
  • 54
    • 0024356811 scopus 로고
    • Phenotypic differences between aαβ versus β T-cell receptor transgenic mice undergoing negative selection
    • Berg LJ, Fazekas de St. Groth B, Groth BF, Pullen AM, Davis MM: Phenotypic differences between aαβ versus β T-cell receptor transgenic mice undergoing negative selection. Nature 1989;340:559-562.
    • (1989) Nature , vol.340 , pp. 559-562
    • Berg, L.J.1    Fazekas De St. Groth, B.2    Groth, B.F.3    Pullen, A.M.4    Davis, M.M.5
  • 55
    • 0025150810 scopus 로고
    • Class I and class II MHC gene products differentially affect the fate of Vb5 bearing thymocytes
    • Bill J, Kanagawa O, Linten J, Utsunomiya Y, Palmer E: Class I and class II MHC gene products differentially affect the fate of Vb5 bearing thymocytes. J Mol Cell Immunol 1990;4:269-279.
    • (1990) J Mol Cell Immunol , vol.4 , pp. 269-279
    • Bill, J.1    Kanagawa, O.2    Linten, J.3    Utsunomiya, Y.4    Palmer, E.5
  • 56
    • 0026453632 scopus 로고
    • Both intrathymic and peripheral selection modulate the differential expression of Vβ5 among CD4+ and CD8+ T cells
    • Fink PJ, Swan K, Turk G, Moore MW, Carbone FR: Both intrathymic and peripheral selection modulate the differential expression of Vβ5 among CD4+ and CD8+ T cells. J Exp Med 1992;176:1733-1738.
    • (1992) J Exp Med , vol.176 , pp. 1733-1738
    • Fink, P.J.1    Swan, K.2    Turk, G.3    Moore, M.W.4    Carbone, F.R.5
  • 57
    • 0023900635 scopus 로고
    • Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes
    • Kisielow P, Bluthmann H, Staerz UD, Steinmetz M, von Boehmer H: Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes. Nature 1988;333:742-746.
    • (1988) Nature , vol.333 , pp. 742-746
    • Kisielow, P.1    Bluthmann, H.2    Staerz, U.D.3    Steinmetz, M.4    Von Boehmer, H.5
  • 58
    • 0023724209 scopus 로고
    • Positive and negative selection of an antigen receptor on T cells in transgenie mice
    • Sha WC, Nelson CA, Newberry RD, Kranz DM, Russell JH, Loh DY: Positive and negative selection of an antigen receptor on T cells in transgenie mice. Nature 1988;336:73-76.
    • (1988) Nature , vol.336 , pp. 73-76
    • Sha, W.C.1    Nelson, C.A.2    Newberry, R.D.3    Kranz, D.M.4    Russell, J.H.5    Loh, D.Y.6
  • 59
    • 0026957466 scopus 로고
    • Self-reactivity and the expression of memory markers vary independently in MRL-Mp+/+ and MRL-Mp-lpr/lpr mice
    • Smyth L, Howell M, Crispe IN: Self-reactivity and the expression of memory markers vary independently in MRL-Mp+/+ and MRL-Mp-lpr/lpr mice. Dev Immunol 1992;2:309-318.
    • (1992) Dev Immunol , vol.2 , pp. 309-318
    • Smyth, L.1    Howell, M.2    Crispe, I.N.3
  • 61
    • 0030200829 scopus 로고    scopus 로고
    • The roles of Fas/APO-1(CD95) and TNF in antigen-induced programmed cell death in T cell receptor transgenic mice
    • Sytwu HK, Liblau RS, McDevitt HO:The roles of Fas/APO-1(CD95) and TNF in antigen-induced programmed cell death in T cell receptor transgenic mice. Immunity 1996;5:17-30.
    • (1996) Immunity , vol.5 , pp. 17-30
    • Sytwu, H.K.1    Liblau, R.S.2    McDevitt, H.O.3
  • 62
    • 0028485743 scopus 로고
    • The Fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice
    • Singer GG, Abbas AK: The Fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice. Immunity 1994;1:365-371.
    • (1994) Immunity , vol.1 , pp. 365-371
    • Singer, G.G.1    Abbas, A.K.2
  • 63
    • 0032402260 scopus 로고    scopus 로고
    • Central T cell tolerance in lupus-prone mice: Influence of autoimmune background and the lpr mutation
    • Fatenejad S, Peng S, Disorbo O, Craft J: Central T cell tolerance in lupus-prone mice: Influence of autoimmune background and the lpr mutation. J Immunol 1998;161:6427-6432.
    • (1998) J Immunol , vol.161 , pp. 6427-6432
    • Fatenejad, S.1    Peng, S.2    Disorbo, O.3    Craft, J.4
  • 64
    • 0030953630 scopus 로고    scopus 로고
    • Autoimmunity caused by disruption of central T cell tolerance: A murine model of drug-induced lupus
    • Kretz-Rommel A, Duncan SR, Ruhin RL: Autoimmunity caused by disruption of central T cell tolerance: A murine model of drug-induced lupus. J Clin Invest 1997;99:1888-1896.
    • (1997) J Clin Invest , vol.99 , pp. 1888-1896
    • Kretz-Rommel, A.1    Duncan, S.R.2    Ruhin, R.L.3
  • 66
    • 0031092710 scopus 로고    scopus 로고
    • αβ T cell regulation and CD40 ligand dependence in murine systemic autoimmunity
    • Peng SL, McNiff JM, Madaio MP, Ma J, Owen M, Flavell RA, et al.: αβ T cell regulation and CD40 ligand dependence in murine systemic autoimmunity. J Immunol 1997;158:2464-2470.
    • (1997) J Immunol , vol.158 , pp. 2464-2470
    • Peng, S.L.1    McNiff, J.M.2    Madaio, M.P.3    Ma, J.4    Owen, M.5    Flavell, R.A.6
  • 67
    • 0028980812 scopus 로고
    • Differential production of interferon-γ and interleukin-4 in response to Th1- and Th2-stimulating pathogens by γδ T cells in vivo
    • Ferrick DA, Schrenzel MD, Mulvania T, Hsieh B, Ferlin WG, Lepper H: Differential production of interferon-γ and interleukin-4 in response to Th1- and Th2-stimulating pathogens by γδ T cells in vivo. Nature 1995;373:255-257.
    • (1995) Nature , vol.373 , pp. 255-257
    • Ferrick, D.A.1    Schrenzel, M.D.2    Mulvania, T.3    Hsieh, B.4    Ferlin, W.G.5    Lepper, H.6
  • 69
    • 0026560991 scopus 로고
    • + T cells induce polyclonal Ig production by committed human B cells. Enhancement by IL-5, specific inhibition of IgA synthesis by IL-4
    • + T cells induce polyclonal Ig production by committed human B cells. Enhancement by IL-5, specific inhibition of IgA synthesis by IL-4. J Immunol 1992;148;1674-1684.
    • (1992) J Immunol , vol.148 , pp. 1674-1684
    • Van Vlasselaer, P.1    Gascan, H.2    De Waal Malefyt, R.3    De Vries, J.E.4
  • 70
    • 0027993367 scopus 로고
    • Regulation of IgE responses to inhaled antigen in mice by antigen-specific γδ T cells
    • McMenamin C, Pimm C, McKersey M, Holt PC: Regulation of IgE responses to inhaled antigen in mice by antigen-specific γδ T cells. Science 1994;265:1869-1871.
    • (1994) Science , vol.265 , pp. 1869-1871
    • McMenamin, C.1    Pimm, C.2    McKersey, M.3    Holt, P.C.4
  • 71
    • 0028457164 scopus 로고
    • Immunoglobulin synthesis and generalized autoimmunity in mice congenitally deficient in αβ(+) T cells
    • Wen L, Roberts SJ, Viney JL, Wong FS, Mallick C, Findly RC, et al.: Immunoglobulin synthesis and generalized autoimmunity in mice congenitally deficient in αβ(+) T cells. Nature 1994;369:654-658.
    • (1994) Nature , vol.369 , pp. 654-658
    • Wen, L.1    Roberts, S.J.2    Viney, J.L.3    Wong, F.S.4    Mallick, C.5    Findly, R.C.6
  • 72
    • 0028927820 scopus 로고
    • γ/δ T lymphocytes express CD40 ligand and induce isotype switching in B lymphocytes
    • Horner AA, Jabara H, Ramesh N, Geha RS: γ/δ T lymphocytes express CD40 ligand and induce isotype switching in B lymphocytes. J Exp Med 1995;181:1239-1244.
    • (1995) J Exp Med , vol.181 , pp. 1239-1244
    • Horner, A.A.1    Jabara, H.2    Ramesh, N.3    Geha, R.S.4
  • 74
    • 0028326477 scopus 로고
    • Exacerbation of established collagen-induced arthritis in mice treated with an anti-T cell receptor antibody
    • Maeda T, Saikawa I, Hotokebuchi T, Sugioka Y, Eto M, Murakami Y, et al.: Exacerbation of established collagen-induced arthritis in mice treated with an anti-T cell receptor antibody. Arthritis Rheum 1994;37:406-413.
    • (1994) Arthritis Rheum , vol.37 , pp. 406-413
    • Maeda, T.1    Saikawa, I.2    Hotokebuchi, T.3    Sugioka, Y.4    Eto, M.5    Murakami, Y.6
  • 75
    • 0030044266 scopus 로고    scopus 로고
    • Depletion of γ/δ T cells does not prevent or ameliorate, but rather aggravates, rat adjuvant arthritis
    • Pelegrí C, Kühnlein P, Buchner E, Schmidt CB, Franch A, Castell M, et al.: Depletion of γ/δ T cells does not prevent or ameliorate, but rather aggravates, rat adjuvant arthritis. Arthritis Rheum 1996;39:204-215.
    • (1996) Arthritis Rheum , vol.39 , pp. 204-215
    • Pelegrí, C.1    Kühnlein, P.2    Buchner, E.3    Schmidt, C.B.4    Franch, A.5    Castell, M.6
  • 76
    • 0009584119 scopus 로고
    • The role of gamma-delta T cells in induction and suppression of autoimmune uveitis
    • Thurau SR, Kühnlein P, Hünig T, Wildner G: The role of gamma-delta T cells in induction and suppression of autoimmune uveitis [Abstract]. Immunobiology 1995;194:157.
    • (1995) Immunobiology , vol.194 , pp. 157
    • Thurau, S.R.1    Kühnlein, P.2    Hünig, T.3    Wildner, G.4
  • 79
    • 0030589323 scopus 로고    scopus 로고
    • Propagation and regulation of systemic autoimmunity by γδ T cells
    • Peng SL, Madaio MP, Hayday AC, Craft J: Propagation and regulation of systemic autoimmunity by γδ T cells. J Immunol 1996;157:5689-5698.
    • (1996) J Immunol , vol.157 , pp. 5689-5698
    • Peng, S.L.1    Madaio, M.P.2    Hayday, A.C.3    Craft, J.4
  • 80
    • 0029975876 scopus 로고    scopus 로고
    • Cytokine imbalance and autoantibody production in T cell receptor-α mutant mice with inflammatory bowel disease
    • Mizoguchi A, Mizoguchi E, Chiba C, Spiekermann GM, Tonegawa S, Nagler-Anderson C, et al.: Cytokine imbalance and autoantibody production in T cell receptor-α mutant mice with inflammatory bowel disease. J Exp Med 1996;183:847-856.
    • (1996) J Exp Med , vol.183 , pp. 847-856
    • Mizoguchi, A.1    Mizoguchi, E.2    Chiba, C.3    Spiekermann, G.M.4    Tonegawa, S.5    Nagler-Anderson, C.6
  • 82
    • 0023204355 scopus 로고
    • Systemic autoimmune disease arises from polyclonal B cell activation
    • Klinman DM, Steinberg AD: Systemic autoimmune disease arises from polyclonal B cell activation. J Exp Med 1987;165:1755-1760.
    • (1987) J Exp Med , vol.165 , pp. 1755-1760
    • Klinman, D.M.1    Steinberg, A.D.2
  • 83
    • 0027998004 scopus 로고
    • T cell-independent and T cell-dependent B cell activation increases IFN-γR expression and renders B cells sensitive to IFN-g-mediated inhibition
    • Abed NS, Chace JH, Cowdery JS: T cell-independent and T cell-dependent B cell activation increases IFN-γR expression and renders B cells sensitive to IFN-g-mediated inhibition. J Immunol 1994;153:3369-3377.
    • (1994) J Immunol , vol.153 , pp. 3369-3377
    • Abed, N.S.1    Chace, J.H.2    Cowdery, J.S.3
  • 85
    • 0031882091 scopus 로고    scopus 로고
    • A new role of B cells in systemic autoimmunity: B cells promote spontaneous T cell activation in MRL-lpr/lpr mice
    • Chan O, Shlomchik MJ: A new role of B cells in systemic autoimmunity: B cells promote spontaneous T cell activation in MRL-lpr/lpr mice. J Immunol 1998;160:51-59.
    • (1998) J Immunol , vol.160 , pp. 51-59
    • Chan, O.1    Shlomchik, M.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.