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Volumn 274, Issue 5288, 1996, Pages 798-801

Hyperresponsive B cells in CD22-deficient mice

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; CD22 ANTIGEN;

EID: 0029909049     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.274.5288.798     Document Type: Article
Times cited : (485)

References (40)
  • 1
    • 0025323932 scopus 로고
    • M. R. Gold, D. A. Law, A, L. DeFranco, Nature 345, 810 (1990); M. A, Campbell and B. M. Sufton, EMBO J. 9, 2125 (1990); J. C. Cambier, C. M. Pleiman, M. R. Clark, Annu. Rev. Immunol. 12, 457 (1994); K. Rajewsky, Nature 381, 751 (1996).
    • (1990) Nature , vol.345 , pp. 810
    • Gold, M.R.1    Law, D.A.2    DeFranco, A.L.3
  • 2
    • 0025292741 scopus 로고
    • M. R. Gold, D. A. Law, A, L. DeFranco, Nature 345, 810 (1990); M. A, Campbell and B. M. Sufton, EMBO J. 9, 2125 (1990); J. C. Cambier, C. M. Pleiman, M. R. Clark, Annu. Rev. Immunol. 12, 457 (1994); K. Rajewsky, Nature 381, 751 (1996).
    • (1990) EMBO J. , vol.9 , pp. 2125
    • Campbell, M.A.1    Sufton, B.M.2
  • 3
    • 0028346563 scopus 로고
    • M. R. Gold, D. A. Law, A, L. DeFranco, Nature 345, 810 (1990); M. A, Campbell and B. M. Sufton, EMBO J. 9, 2125 (1990); J. C. Cambier, C. M. Pleiman, M. R. Clark, Annu. Rev. Immunol. 12, 457 (1994); K. Rajewsky, Nature 381, 751 (1996).
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 457
    • Cambier, J.C.1    Pleiman, C.M.2    Clark, M.R.3
  • 4
    • 0030006070 scopus 로고    scopus 로고
    • M. R. Gold, D. A. Law, A, L. DeFranco, Nature 345, 810 (1990); M. A, Campbell and B. M. Sufton, EMBO J. 9, 2125 (1990); J. C. Cambier, C. M. Pleiman, M. R. Clark, Annu. Rev. Immunol. 12, 457 (1994); K. Rajewsky, Nature 381, 751 (1996).
    • (1996) Nature , vol.381 , pp. 751
    • Rajewsky, K.1
  • 5
    • 0022590747 scopus 로고
    • B. Dörken et al., J. Immunol. 136, 4470 (1986); L. D. Powell, D. Sgroi, E. R. Sjoberg, I, Stamenkovic, A. Varki, J. Biol. Chem. 268, 7019 (1993); C.-L. Law, S. P. Sidorenko, E. A. Clark, Immunol. Today 15, 442 (1994).
    • (1986) J. Immunol. , vol.136 , pp. 4470
    • Dörken, B.1
  • 7
    • 0028070102 scopus 로고
    • B. Dörken et al., J. Immunol. 136, 4470 (1986); L. D. Powell, D. Sgroi, E. R. Sjoberg, I, Stamenkovic, A. Varki, J. Biol. Chem. 268, 7019 (1993); C.-L. Law, S. P. Sidorenko, E. A. Clark, Immunol. Today 15, 442 (1994).
    • (1994) Immunol. Today , vol.15 , pp. 442
    • Law, C.-L.1    Sidorenko, S.P.2    Clark, E.A.3
  • 8
    • 0026437805 scopus 로고
    • R. J. Schulte, M. A. Campbell, W. H. Fischer, B. M. Sefton, Science 258, 1001 (1992); C. J. G. Peaker and M. S. Neuberger, Eur. J. Immunol. 23, 1358 (1993); C. LePrince, K. E. Draves, R. L. Geahlen, J. A. Ledbetter, E. A. Clark, Proc Nall. Acad. Sci. U.S.A. 90, 3236 (1993); G. T, Williams, C. J. G. Peaker, K. J Patel, M. S. Neuberger, ibid. 91, 474 (1994).
    • (1992) Science , vol.258 , pp. 1001
    • Schulte, R.J.1    Campbell, M.A.2    Fischer, W.H.3    Sefton, B.M.4
  • 9
    • 0027175115 scopus 로고
    • R. J. Schulte, M. A. Campbell, W. H. Fischer, B. M. Sefton, Science 258, 1001 (1992); C. J. G. Peaker and M. S. Neuberger, Eur. J. Immunol. 23, 1358 (1993); C. LePrince, K. E. Draves, R. L. Geahlen, J. A. Ledbetter, E. A. Clark, Proc Nall. Acad. Sci. U.S.A. 90, 3236 (1993); G. T, Williams, C. J. G. Peaker, K. J Patel, M. S. Neuberger, ibid. 91, 474 (1994).
    • (1993) Eur. J. Immunol. , vol.23 , pp. 1358
    • Peaker, C.J.G.1    Neuberger, M.S.2
  • 10
    • 0027416042 scopus 로고
    • R. J. Schulte, M. A. Campbell, W. H. Fischer, B. M. Sefton, Science 258, 1001 (1992); C. J. G. Peaker and M. S. Neuberger, Eur. J. Immunol. 23, 1358 (1993); C. LePrince, K. E. Draves, R. L. Geahlen, J. A. Ledbetter, E. A. Clark, Proc Nall. Acad. Sci. U.S.A. 90, 3236 (1993); G. T, Williams, C. J. G. Peaker, K. J Patel, M. S. Neuberger, ibid. 91, 474 (1994).
    • (1993) Proc Nall. Acad. Sci. U.S.A. , vol.90 , pp. 3236
    • LePrince, C.1    Draves, K.E.2    Geahlen, R.L.3    Ledbetter, J.A.4    Clark, E.A.5
  • 11
    • 0028009742 scopus 로고
    • R. J. Schulte, M. A. Campbell, W. H. Fischer, B. M. Sefton, Science 258, 1001 (1992); C. J. G. Peaker and M. S. Neuberger, Eur. J. Immunol. 23, 1358 (1993); C. LePrince, K. E. Draves, R. L. Geahlen, J. A. Ledbetter, E. A. Clark, Proc Nall. Acad. Sci. U.S.A. 90, 3236 (1993); G. T, Williams, C. J. G. Peaker, K. J Patel, M. S. Neuberger, ibid. 91, 474 (1994).
    • (1994) Proc Nall. Acad. Sci. U.S.A. , vol.91 , pp. 474
    • Williams, G.T.1    Peaker, C.J.G.2    Patel, K.J.3    Neuberger, M.S.4
  • 12
    • 0029012969 scopus 로고
    • G. M. Doody et al., Science 269, 242 (1995).
    • (1995) Science , vol.269 , pp. 242
    • Doody, G.M.1
  • 13
    • 0029048060 scopus 로고
    • M. A. Campbell and N. R. Klinman, Eur. J. Immunol. 25, 1573 (1995); G. Pani, M. Kozlowski, J. C, Gambier, G. B. Mills, K. A. Siminovitch, J. Exp. Med. 181, 2077 (1995); C.-L Law et al., ibid. 183, 547 (1996).
    • (1995) Eur. J. Immunol. , vol.25 , pp. 1573
    • Campbell, M.A.1    Klinman, N.R.2
  • 15
    • 0030047811 scopus 로고    scopus 로고
    • M. A. Campbell and N. R. Klinman, Eur. J. Immunol. 25, 1573 (1995); G. Pani, M. Kozlowski, J. C, Gambier, G. B. Mills, K. A. Siminovitch, J. Exp. Med. 181, 2077 (1995); C.-L Law et al., ibid. 183, 547 (1996).
    • (1996) J. Exp. Med. , vol.183 , pp. 547
    • Law, C.-L.1
  • 16
    • 0023646810 scopus 로고
    • r clones analyzed carried targeted integrations. Two of the targeted ES clones were used to establish chimeric mice by injection into C57BL/6 blastocysts, and germline transmission was obtained on further crossing with both C57BL/6 and BALB/c females.
    • (1987) Cell , vol.51 , pp. 503
    • Thomas, K.R.1    Capecchi, M.R.2
  • 17
    • 0028950996 scopus 로고
    • r clones analyzed carried targeted integrations. Two of the targeted ES clones were used to establish chimeric mice by injection into C57BL/6 blastocysts, and germline transmission was obtained on further crossing with both C57BL/6 and BALB/c females.
    • (1995) Nature Genet. , vol.9 , pp. 376
    • Smith, A.J.H.1
  • 18
    • 10544232735 scopus 로고    scopus 로고
    • note
    • B-lineage cells in bone marrow of CD22-deficient mice and control littermates were compared by flow cytometry for expression of IgM, CD45 (B220), CD19, and CD43.
  • 20
    • 10544244708 scopus 로고    scopus 로고
    • note
    • -/- animals.
  • 23
    • 0023271976 scopus 로고
    • A. Pezzutto, B. Dörken, G. Moldenhauer, E. A. Clark, J. Immunol. 138, 98 (1987); A. Pezzutto, P. S. Rabinovitch, B. Dörken, G. Moldenhauer, E. A. Clark, ibid. 140, 1791 (1988); N. Chaouchi, A. Vazquez, P. Galanaud, C. Leprince, ibid. 154, 3096 (1995); J. Tuscano, P. Engel, T. F. Tedder, J. H. Kehrl, Blood 87, 4723 (1996); J. M. Tuscano, P. Engel, T. F. Tedder, A. Agarwal, J. H. Kehrl, Eur. J. Immunol. 26, 1246 (1996).
    • (1987) J. Immunol. , vol.138 , pp. 98
    • Pezzutto, A.1    Dörken, B.2    Moldenhauer, G.3    Clark, E.A.4
  • 24
    • 0023907422 scopus 로고
    • A. Pezzutto, B. Dörken, G. Moldenhauer, E. A. Clark, J. Immunol. 138, 98 (1987); A. Pezzutto, P. S. Rabinovitch, B. Dörken, G. Moldenhauer, E. A. Clark, ibid. 140, 1791 (1988); N. Chaouchi, A. Vazquez, P. Galanaud, C. Leprince, ibid. 154, 3096 (1995); J. Tuscano, P. Engel, T. F. Tedder, J. H. Kehrl, Blood 87, 4723 (1996); J. M. Tuscano, P. Engel, T. F. Tedder, A. Agarwal, J. H. Kehrl, Eur. J. Immunol. 26, 1246 (1996).
    • (1988) J. Immunol. , vol.140 , pp. 1791
    • Pezzutto, A.1    Rabinovitch, P.S.2    Dörken, B.3    Moldenhauer, G.4    Clark, E.A.5
  • 25
    • 0028946557 scopus 로고
    • A. Pezzutto, B. Dörken, G. Moldenhauer, E. A. Clark, J. Immunol. 138, 98 (1987); A. Pezzutto, P. S. Rabinovitch, B. Dörken, G. Moldenhauer, E. A. Clark, ibid. 140, 1791 (1988); N. Chaouchi, A. Vazquez, P. Galanaud, C. Leprince, ibid. 154, 3096 (1995); J. Tuscano, P. Engel, T. F. Tedder, J. H. Kehrl, Blood 87, 4723 (1996); J. M. Tuscano, P. Engel, T. F. Tedder, A. Agarwal, J. H. Kehrl, Eur. J. Immunol. 26, 1246 (1996).
    • (1995) J. Immunol. , vol.154 , pp. 3096
    • Chaouchi, N.1    Vazquez, A.2    Galanaud, P.3    Leprince, C.4
  • 26
    • 0029944192 scopus 로고    scopus 로고
    • A. Pezzutto, B. Dörken, G. Moldenhauer, E. A. Clark, J. Immunol. 138, 98 (1987); A. Pezzutto, P. S. Rabinovitch, B. Dörken, G. Moldenhauer, E. A. Clark, ibid. 140, 1791 (1988); N. Chaouchi, A. Vazquez, P. Galanaud, C. Leprince, ibid. 154, 3096 (1995); J. Tuscano, P. Engel, T. F. Tedder, J. H. Kehrl, Blood 87, 4723 (1996); J. M. Tuscano, P. Engel, T. F. Tedder, A. Agarwal, J. H. Kehrl, Eur. J. Immunol. 26, 1246 (1996).
    • (1996) Blood , vol.87 , pp. 4723
    • Tuscano, J.1    Engel, P.2    Tedder, T.F.3    Kehrl, J.H.4
  • 27
    • 0030053270 scopus 로고    scopus 로고
    • A. Pezzutto, B. Dörken, G. Moldenhauer, E. A. Clark, J. Immunol. 138, 98 (1987); A. Pezzutto, P. S. Rabinovitch, B. Dörken, G. Moldenhauer, E. A. Clark, ibid. 140, 1791 (1988); N. Chaouchi, A. Vazquez, P. Galanaud, C. Leprince, ibid. 154, 3096 (1995); J. Tuscano, P. Engel, T. F. Tedder, J. H. Kehrl, Blood 87, 4723 (1996); J. M. Tuscano, P. Engel, T. F. Tedder, A. Agarwal, J. H. Kehrl, Eur. J. Immunol. 26, 1246 (1996).
    • (1996) Eur. J. Immunol. , vol.26 , pp. 1246
    • Tuscano, J.M.1    Engel, P.2    Tedder, T.F.3    Agarwal, A.4    Kehrl, J.H.5
  • 30
    • 0028961264 scopus 로고
    • J. G. Oyster and C. C. Goodnow, Immunity 2, 13 (1995); L. D. Shultz and M. C. Green, J. Immunol. 116, 936 (1976); C. L. Sidman, L. D. Schultz, R. R. Hardy, K. Hayakawa, L. A. Herzenberg, Science 232, 1423 (1986).
    • (1995) Immunity , vol.2 , pp. 13
    • Oyster, J.G.1    Goodnow, C.C.2
  • 31
    • 0017105510 scopus 로고
    • J. G. Oyster and C. C. Goodnow, Immunity 2, 13 (1995); L. D. Shultz and M. C. Green, J. Immunol. 116, 936 (1976); C. L. Sidman, L. D. Schultz, R. R. Hardy, K. Hayakawa, L. A. Herzenberg, Science 232, 1423 (1986).
    • (1976) J. Immunol. , vol.116 , pp. 936
    • Shultz, L.D.1    Green, M.C.2
  • 33
    • 0030070349 scopus 로고    scopus 로고
    • T. Benatar et al., J. Exp. Med. 183, 329 (1996); J. G. Cyster et al., Nature 381, 325 (1996).
    • (1996) J. Exp. Med. , vol.183 , pp. 329
    • Benatar, T.1
  • 34
    • 0030023652 scopus 로고    scopus 로고
    • T. Benatar et al., J. Exp. Med. 183, 329 (1996); J. G. Cyster et al., Nature 381, 325 (1996).
    • (1996) Nature , vol.381 , pp. 325
    • Cyster, J.G.1
  • 37
    • 10544229903 scopus 로고    scopus 로고
    • note
    • i was monitored with a fluorescence-activated cell sorting (FACS) flow cytometer and LYSIS ∥ software (Beckton Dickinson) by measuring changes in the ratio of indo-1 emissions at 395 and 530 nm in real time.
  • 38
    • 0021244743 scopus 로고
    • 3H]thymidine, after which the radioactivity incorporated into macromolecules was measured. Similar results were obtained with three sets of CD22-deficient and normal mice. The mAb b-7-6 [M. H. Julius, C. H. Heusser, K.-U. Hartmann, Eur. J. Immunol. 14, 753 (1984)] was a gift from M. Holman and G. Klaus.
    • (1984) Eur. J. Immunol. , vol.14 , pp. 753
    • Julius, M.H.1    Heusser, C.H.2    Hartmann, K.-U.3
  • 40
    • 10544239666 scopus 로고    scopus 로고
    • note
    • We thank T. Rabbitts, A. Warren, and A. Smith for advice on ES cell culture; T. Langford and G. King for animal handling; A. Riddell and R. Hicks for performing flow cytometry analyses, M, C. Lamers and E. A. Clark for exchanging information before publication; and S. Bell, P. Dempsey, D. Fearon, A. MacKenzie, and members of our laboratory for advice and discussions. T.O'K. received a fellowship from Human Frontier Science Program Organization and S.L.D. and T.O'K. were also supported by an International Research Scholars award from Howard Hughes Medical Institute to M.S.N.


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