-
1
-
-
33745083936
-
The emerging roles of DNA methylation in the clinical management of prostate cancer
-
DOI 10.1677/erc.1.01184
-
Perry, A. S., Foley, R., woodson, K. & Lawler, M. The emerging roles of DNA methylation in the clinical management of prostate canceR. EndocR. Relat. Cancer 13, 357-377 (2006). (Pubitemid 43886663)
-
(2006)
Endocrine-Related Cancer
, vol.13
, Issue.2
, pp. 357-377
-
-
Perry, A.S.1
Foley, R.2
Woodson, K.3
Lawler, M.4
-
2
-
-
33748371194
-
Epigenetics of prostate cancer: Beyond DNA methylation
-
DOI 10.1111/j.1582-4934.2006.tb00293.x
-
Schulz, W. A. & Hatina, J. Epigenetics of prostate cancer: beyond DNA methylatioN. J. Cell. Mol. Med. 10, 100-125 (2006). (Pubitemid 44874294)
-
(2006)
Journal of Cellular and Molecular Medicine
, vol.10
, Issue.1
, pp. 100-125
-
-
Schulz, W.A.1
Hatina, J.2
-
3
-
-
78049485263
-
Estimates of worldwide burden of cancer in 2008: Globocan 2008
-
doi:10.1002/ijc.25516.
-
Ferlay, J., et al. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int. J. Cancer doi:10.1002/ijc.25516.
-
Int. J. Cancer
-
-
Ferlay, J.1
-
4
-
-
73649094457
-
New developments in the medical management of prostate cancer
-
Kohli, M. & Tindall, D. J. New developments in the medical management of prostate canceR. Mayo CliN. Proc. 85, 77-86 (2010).
-
(2010)
Mayo CliN. Proc.
, vol.85
, pp. 77-86
-
-
Kohli, M.1
Tindall, D.J.2
-
6
-
-
0022540321
-
CpG-rich islands and the function of DNA methylation
-
Bird, A. P. CpG-rich islands and the function of DNA methylatioN. Nature 321, 209-213 (1986). (Pubitemid 16016411)
-
(1986)
Nature
, vol.321
, Issue.6067
, pp. 209-213
-
-
Bird, A.P.1
-
7
-
-
0024342297
-
Cytosine methylation and the fate of CpG dinucleotides in vertebrates genomes
-
Cooper, D. N. & Krawczak, M. Cytosine methylation and the fate of CpG dinucleotides in vertebrate genomes. Hum. Genet. 83, 181-188 (1989). (Pubitemid 19234570)
-
(1989)
Human Genetics
, vol.83
, Issue.2
, pp. 181-188
-
-
Cooper, D.N.1
Krawczak, M.2
-
8
-
-
70450217879
-
Human DNA methylomes at base resolution show widespread epigenomic differences
-
Lister, R., et al. Human DNA methylomes at base resolution show widespread epigenomic differences. Nature 462, 315-322 (2009).
-
(2009)
Nature
, vol.462
, pp. 315-322
-
-
Lister, R.1
-
9
-
-
77954504873
-
Conserved role of intragenic DNA methylation in regulating alternative promoters
-
Maunakea, A.K., et al. Conserved role of intragenic DNA methylation in regulating alternative promoters. Nature 466, 253-257 (2010).
-
(2010)
Nature
, vol.466
, pp. 253-257
-
-
Maunakea, A.K.1
-
10
-
-
0025294471
-
CpG methylation inhibits proenkephalin gene expression and binding of the transcription factor AP-2
-
Comb, M. & Goodman, H. M. CpG methylation inhibits proenkephalin gene expression and binding of the transcription factor AP-2. Nucleic Acids Res. 18, 3975-3982 (1990).
-
(1990)
Nucleic Acids Res.
, vol.18
, pp. 3975-3982
-
-
Comb, M.1
Goodman, H.M.2
-
11
-
-
0033566127
-
Site-specific DNA methylation in the neurofibromatosis (NF1) promoter interferes with binding of CREB and SP1 transcription factors
-
DOI 10.1038/sj.onc.1202764
-
Mancini, D. N., Singh, S. M., Archer, T. K. & Rodenhiser, D. I. Site-specific DNA methylation in the neurofibromatosis (NF1) promoter interferes with binding of CREB and SP1 transcription factors. Oncogene 18, 4108-4119 (1999). (Pubitemid 29363918)
-
(1999)
Oncogene
, vol.18
, Issue.28
, pp. 4108-4119
-
-
Mancini, D.N.1
Singh, S.M.2
Archer, T.K.3
Rodenhiser, D.4
-
12
-
-
31344466008
-
DNA methylation and gene silencing in cancer
-
DOI 10.1038/ncponc0354, PII N0354
-
Baylin, S. B. DNA methylation and gene silencing in canceR. Nat. CliN. Pract. Oncol. 2, S4-S11 (2005). (Pubitemid 43135229)
-
(2005)
Nature Clinical Practice Oncology
, vol.2
, Issue.SUPPL. 1
-
-
Baylin, S.B.1
-
13
-
-
0032574977
-
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
-
DOI 10.1038/30764
-
Nan, X., et al. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature 393, 386-389 (1998). (Pubitemid 28269714)
-
(1998)
Nature
, vol.393
, Issue.6683
, pp. 386-389
-
-
Nan, X.1
Ng, H.-H.2
Johnson, C.A.3
Laherty, C.D.4
Turner, B.M.5
Eisenman, R.N.6
Bird, A.7
-
14
-
-
0031837109
-
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
-
DOI 10.1038/561
-
Jones, P.L., et al. Methylated DNA and MeCP2 recruit histone deacetylase to repress transcriptioN. Nat. Genet. 19, 187-191 (1998). (Pubitemid 28248804)
-
(1998)
Nature Genetics
, vol.19
, Issue.2
, pp. 187-191
-
-
Jones, P.L.1
Veenstra, G.J.C.2
Wade, P.A.3
Vermaak, D.4
Kass, S.U.5
Landsberger, N.6
Strouboulis, J.7
Wolffe, A.P.8
-
15
-
-
0032574859
-
Methylation meets acetylation
-
DOI 10.1038/30613
-
Bestor, T. H. Gene silencing. Methylation meets acetylatioN. Nature 393, 311-312 (1998). (Pubitemid 28269689)
-
(1998)
Nature
, vol.393
, Issue.6683
, pp. 311-312
-
-
Bestor, T.H.1
-
16
-
-
77954659099
-
Relationship between nucleosome positioning and DNA methylation
-
Chodavarapu, R.K., et al. Relationship between nucleosome positioning and DNA methylatioN. Nature 466, 388-392 (2010).
-
(2010)
Nature
, vol.466
, pp. 388-392
-
-
Chodavarapu, R.K.1
-
17
-
-
12144289173
-
Hypermethylation of CpG Islands in Primary and Metastatic Human Prostate Cancer
-
DOI 10.1158/0008-5472.CAN-03-3972
-
Yegnasubramanian, S., et al. Hypermethylation of CpG islands in primary and metastatic human prostate canceR. Cancer Res. 64, 1975-1986 (2004). (Pubitemid 38339443)
-
(2004)
Cancer Research
, vol.64
, Issue.6
, pp. 1975-1986
-
-
Yegnasubramanian, S.1
Kowalski, J.2
Gonzalgo, M.L.3
Zahurak, M.4
Piantadosi, S.5
Walsh, P.C.6
Bova, G.S.7
De Marzo, A.M.8
Isaacs, W.B.9
Nelson, W.G.10
-
18
-
-
19944429845
-
A quantitative promoter methylation profile of prostate cancer
-
DOI 10.1158/1078-0432.CCR-04-0894
-
Jeronimo, C., et al. A quantitative promoter methylation profile of prostate canceR. CliN. Cancer Res. 10, 8472-8478 (2004). (Pubitemid 40053412)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.24
, pp. 8472-8478
-
-
Jeronimo, C.1
Henrique, R.2
Hoque, M.O.3
Mambo, E.4
Ribeiro, F.R.5
Varzim, G.6
Oliveira, J.7
Teixeira, M.R.8
Lopes, C.9
Sidransky, D.10
-
19
-
-
1142275110
-
Aberrant CpG island hypermethylation of multiple genes in prostate cancer and prostatic intraepithelial neoplasia
-
DOI 10.1002/path.1503
-
Kang, G. H., Lee, S., Lee, H. J. & Hwang, K. S. Aberrant CpG island hypermethylation of multiple genes in prostate cancer and prostatic intraepithelial neoplasia. J. Pathol. 202, 233-240 (2004). (Pubitemid 38208661)
-
(2004)
Journal of Pathology
, vol.202
, Issue.2
, pp. 233-240
-
-
Kang, G.H.1
Lee, S.2
Lee, H.J.3
Hwang, K.S.4
-
20
-
-
0036184623
-
Aberrant promoter methylation profile of prostate cancers and its relationship to clinicopathological features
-
Maruyama, R., et al. Aberrant promoter methylation profile of prostate cancers and its relationship to clinicopathological features. CliN. Cancer Res. 8, 514-519 (2002). (Pubitemid 34193971)
-
(2002)
Clinical Cancer Research
, vol.8
, Issue.2
, pp. 514-519
-
-
Maruyama, R.1
Toyooka, S.2
Toyooka, K.O.3
Virmani, A.K.4
Zochbauer-Muller, S.5
Farinas, A.J.6
Minna, J.D.7
McConnell, J.8
Frenkel, E.P.9
Gazdar, A.F.10
-
21
-
-
0037029021
-
Methylation and inactivation of estrogen, progesterone, and androgen receptors in prostate cancer
-
Sasaki, M., et al. Methylation and inactivation of estrogen, progesterone, and androgen receptors in prostate canceR. J. Natl Cancer Inst. 94, 384-390 (2002). (Pubitemid 34257482)
-
(2002)
Journal of the National Cancer Institute
, vol.94
, Issue.5
, pp. 384-390
-
-
Sasaki, M.1
Tanaka, Y.2
Perinchery, G.3
Dharia, A.4
Kotcherguina, I.5
Fujimoto, S.I.6
Dahiya, R.7
-
22
-
-
69249119942
-
Epigenetic alterations in human prostate cancers
-
Nelson, W. G., De Marzo, A. M. & Yegnasubramanian, S. Epigenetic alterations in human prostate cancers. Endocrinology 150, 3991-4002 (2009).
-
(2009)
Endocrinology
, vol.150
, pp. 3991-4002
-
-
Nelson, W.G.1
De Marzo, A.M.2
Yegnasubramanian, S.3
-
23
-
-
34347203711
-
Epigenetics of prostate cancer
-
Li, L. C. Epigenetics of prostate canceR. Front. BioscI. 12, 3377-3397 (2007).
-
(2007)
Front. BioscI.
, vol.12
, pp. 3377-3397
-
-
Li, L.C.1
-
24
-
-
0031879694
-
CG island methylation changes near the GSTP1 gene in prostatic intraepithelial neoplasia
-
Brooks, J.D., et al. CG island methylation changes near the GSTP1 gene in prostatic intraepithelial neoplasia. Cancer Epidemiol. Biomarkers PreV. 7, 531-536 (1998). (Pubitemid 28354117)
-
(1998)
Cancer Epidemiology Biomarkers and Prevention
, vol.7
, Issue.6
, pp. 531-536
-
-
Brooks, J.D.1
Weinstein, M.2
Lin, X.3
Sun, Y.4
Pin, S.S.5
Bova, G.S.6
Epstein, J.I.7
Isaacs, W.B.8
Nelson, W.G.9
-
25
-
-
34248546744
-
In silico mining identifies IGFBP3 as a novel target of methylation in prostate cancer
-
DOI 10.1038/sj.bjc.6603767, PII 6603767
-
Perry, A.S., et al. In silico mining identifies IGFBP3 as a novel target of methylation in prostate canceR. BR. J. Cancer 96, 1587-1594 (2007). (Pubitemid 46762961)
-
(2007)
British Journal of Cancer
, vol.96
, Issue.10
, pp. 1587-1594
-
-
Perry, A.S.1
Loftus, B.2
Moroose, R.3
Lynch, T.H.4
Hollywood, D.5
Watson, R.W.G.6
Woodson, K.7
Lawler, M.8
-
26
-
-
0028152397
-
Cytidine methylation of regulatory sequences near the pi-class glutathione S.-transferase gene accompanies human prostatic carcinogenesis
-
Lee, W.H., et al. Cytidine methylation of regulatory sequences near the pi-class glutathione S.-transferase gene accompanies human prostatic carcinogenesis. Proc. Natl Acad. ScI. USA 91, 11733-11737 (1994).
-
(1994)
Proc. Natl Acad. ScI. USA
, vol.91
, pp. 11733-11737
-
-
Lee, W.H.1
-
27
-
-
10044239471
-
Global hypomethylation is common in prostate cancer cells: A quantitative predictor for clinical outcome?
-
DOI 10.1016/j.cancergencyto.2004.04.004, PII S0165460804001724
-
Brothman, A.R., et al. Global hypomethylation is common in prostate cancer cells: a quantitative predictor for clinical outcome? Cancer Genet. Cytogenet. 156, 31-36 (2005). (Pubitemid 39601056)
-
(2005)
Cancer Genetics and Cytogenetics
, vol.156
, Issue.1
, pp. 31-36
-
-
Brothman, A.R.1
Swanson, G.2
Maxwell, T.M.3
Cui, J.4
Murphy, K.J.5
Herrick, J.6
Speights, V.O.7
Isaac, J.8
Rohr, L.R.9
-
28
-
-
55349130961
-
DNA hypomethylation arises later in prostate cancer progression than CpG island hypermethylation and contributes to metastatic tumor heterogeneity
-
Yegnasubramanian, S., et al. DNA hypomethylation arises later in prostate cancer progression than CpG island hypermethylation and contributes to metastatic tumor heterogeneity. Cancer Res. 68, 8954-8967 (2008).
-
(2008)
Cancer Res.
, vol.68
, pp. 8954-8967
-
-
Yegnasubramanian, S.1
-
29
-
-
4644329189
-
Coordinate hypermethylation at specific genes in prostate carcinoma precedes LINE-1 hypomethylation
-
DOI 10.1038/sj.bjc.6602030
-
Florl, A.R., et al. Coordinate hypermethylation at specific genes in prostate carcinoma precedes LINE-1 hypomethylatioN. BR. J. Cancer 91, 985-994 (2004). (Pubitemid 39273795)
-
(2004)
British Journal of Cancer
, vol.91
, Issue.5
, pp. 985-994
-
-
Florl, A.R.1
Steinhoff, C.2
Muller, M.3
Seifert, H.-H.4
Hader, C.5
Engers, R.6
Ackermann, R.7
Schulz, W.A.8
-
30
-
-
3042658499
-
DNA demethylation and cancer: Therapeutic implications
-
DOI 10.1016/j.canlet.2004.04.009, PII S0304383504003155
-
Szyf, M., Pakneshan, P. & Rabbani, S. A. DNA demethylation and cancer: therapeutic implications. Cancer Lett. 211, 133-143 (2004). (Pubitemid 38824627)
-
(2004)
Cancer Letters
, vol.211
, Issue.2
, pp. 133-143
-
-
Szyf, M.1
Pakneshan, P.2
Rabbani, S.A.3
-
31
-
-
19944432186
-
Increased heparanase expression is caused by promoter hypomethylation and up-regulation of transcriptional factor early growth response-1 in human prostate cancer
-
Ogishima, T., et al. Increased heparanase expression is caused by promoter hypomethylation and up-regulation of transcriptional factor early growth response-1 in human prostate canceR. CliN. Cancer Res. 11, 1028-1036 (2005). (Pubitemid 40175750)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.3
, pp. 1028-1036
-
-
Ogishima, T.1
Shiina, H.2
Breault, J.E.3
Tabatabai, L.4
Bassett, W.W.5
Enokida, H.6
Li, L.-C.7
Kawakami, T.8
Urakami, S.9
Ribeiro-Filho, L.A.10
Terashima, M.11
Fujime, M.12
Igawa, M.13
Dahiya, R.14
-
32
-
-
34948842950
-
Hypomethylation of WNT5A, CRIP1 and S100P in prostate cancer
-
DOI 10.1038/sj.onc.1210472, PII 1210472
-
Wang, Q., et al. Hypomethylation of wNT5A, CRIP1 and S100P in prostate canceR. Oncogene 26, 6560-6565 (2007). (Pubitemid 47530597)
-
(2007)
Oncogene
, vol.26
, Issue.45
, pp. 6560-6565
-
-
Wang, Q.1
Williamson, M.2
Bott, S.3
Brookman-Amissah, N.4
Freeman, A.5
Nariculam, J.6
Hubank, M.J.F.7
Ahmed, A.8
Masters, J.R.9
-
33
-
-
33749483782
-
Alteration of the methylation status of tumor-promoting genes decreases prostate cancer cell invasiveness and tumorigenesis in vitro and in vivo
-
DOI 10.1158/0008-5472.CAN-06-1954
-
Shukeir, N., Pakneshan, P., Chen, G., Szyf, M. & Rabbani, S. A. Alteration of the methylation status of tumor-promoting genes decreases prostate cancer cell invasiveness and tumorigenesis in vitro and in vivo. Cancer Res. 66, 9202-9210 (2006). (Pubitemid 44521141)
-
(2006)
Cancer Research
, vol.66
, Issue.18
, pp. 9202-9210
-
-
Shukeir, N.1
Pakneshan, P.2
Chen, G.3
Szyf, M.4
Rabbani, S.A.5
-
34
-
-
3743083805
-
Clonal inheritance of the pattern of DNA methylation in mouse cells
-
Stein, R., Gruenbaum, Y., Pollack, Y., Razin, A. & Cedar, H. Clonal inheritance of the pattern of DNA methylation in mouse cells. Proc. Natl Acad. ScI. USA 79, 61-65 (1982). (Pubitemid 12181486)
-
(1982)
Proceedings of the National Academy of Sciences of the United States of America
, vol.79
, Issue.1
, pp. 61-65
-
-
Stein, R.1
Gruenbaum, Y.2
Pollack, Y.3
-
35
-
-
34648833002
-
UHRF1 plays a role in maintaining DNA methylation in mammalian cells
-
DOI 10.1126/science.1147939
-
Bostick, M., et al. UHRF1 plays a role in maintaining DNA methylation in mammalian cells. Science 317, 1760-1764 (2007). (Pubitemid 47461842)
-
(2007)
Science
, vol.317
, Issue.5845
, pp. 1760-1764
-
-
Bostick, M.1
Jong, K.K.2
Esteve, P.-O.3
Clark, A.4
Pradhan, S.5
Jacobsen, S.E.6
-
36
-
-
36849072573
-
The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA
-
DOI 10.1038/nature06397, PII NATURE06397
-
Sharif, J., et al. The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA. Nature 450, 908-912 (2007). (Pubitemid 350231331)
-
(2007)
Nature
, vol.450
, Issue.7171
, pp. 908-912
-
-
Sharif, J.1
Muto, M.2
Takebayashi, S.-I.3
Suetake, I.4
Iwamatsu, A.5
Endo, T.A.6
Shinga, J.7
Mizutani-Koseki, Y.8
Toyoda, T.9
Okamura, K.10
Tajima, S.11
Mitsuya, K.12
Okano, M.13
Koseki, H.14
-
37
-
-
7044245474
-
ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain
-
DOI 10.1038/sj.onc.1208053
-
Unoki, M., Nishidate, T. & Nakamura, Y. ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domaiN. Oncogene 23, 7601-7610 (2004). (Pubitemid 39424918)
-
(2004)
Oncogene
, vol.23
, Issue.46
, pp. 7601-7610
-
-
Unoki, M.1
Nishidate, T.2
Nakamura, Y.3
-
38
-
-
53649088595
-
Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1
-
Avvakumov, G.V., et al. Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1. Nature 455, 822-825 (2008).
-
(2008)
Nature
, vol.455
, pp. 822-825
-
-
Avvakumov, G.V.1
-
39
-
-
0026439115
-
A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei
-
Leonhardt, H., Page, A. W., weier, H. U. & Bestor, T. H. A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nucleI. Cell 71, 865-873 (1992).
-
(1992)
Cell
, vol.71
, pp. 865-873
-
-
Leonhardt, H.1
Page, A.W.2
Weier, H.U.3
Bestor, T.H.4
-
40
-
-
0031860739
-
Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases [1]
-
DOI 10.1038/890
-
Okano, M., Xie, S. & Li, E. Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases. Nat. Genet. 19, 219-220 (1998). (Pubitemid 28309328)
-
(1998)
Nature Genetics
, vol.19
, Issue.3
, pp. 219-220
-
-
Okano, M.1
Xie, S.2
Li, E.3
-
41
-
-
0042132027
-
Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b
-
DOI 10.1128/MCB.23.16.5594-5605.2003
-
Chen, T., Ueda, Y., Dodge, J. E., wang, Z. & Li, E. Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b. Mol. Cell Biol. 23, 5594-5605 (2003). (Pubitemid 36951325)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.16
, pp. 5594-5605
-
-
Chen, T.1
Ueda, Y.2
Dodge, J.E.3
Wang, Z.4
Li, E.5
-
42
-
-
18344390653
-
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells
-
DOI 10.1038/416552a
-
Rhee, I., et al. DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Nature 416, 552-556 (2002). (Pubitemid 34288859)
-
(2002)
Nature
, vol.416
, Issue.6880
, pp. 552-556
-
-
Rhee, I.1
Bachman, K.E.2
Park, B.H.3
Jair, K.-W.4
Yen, R.-W.C.5
Schuebel, K.E.6
Cui, H.7
Feinberg, A.P.8
Lengauer, C.9
Kinzler, K.W.10
Baylin, S.B.11
Vogelstein, B.12
-
43
-
-
0141988726
-
Double RNA interference of DNMT3b and DNMT1 enhances DNA demethylation and gene reactivation
-
Leu, Y.W., et al. Double RNA interference of DNMT3b and DNMT1 enhances DNA demethylation and gene reactivatioN. Cancer Res. 63, 6110-6115 (2003).
-
(2003)
Cancer Res.
, vol.63
, pp. 6110-6115
-
-
Leu, Y.W.1
-
44
-
-
0033945861
-
DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci
-
DOI 10.1038/77023
-
Rountree, M. R., Bachman, K. E. & Baylin, S. B. DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication focI. Nat. Genet. 25, 269-277 (2000). (Pubitemid 30437311)
-
(2000)
Nature Genetics
, vol.25
, Issue.3
, pp. 269-277
-
-
Rountree, M.R.1
Bachman, K.E.2
Baylin, S.B.3
-
45
-
-
0033919595
-
DNMT1 forms a complex with RB, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters
-
DOI 10.1038/77124
-
Robertson, K.D., et al. DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters. Nat. Genet. 25, 338-342 (2000). (Pubitemid 30437325)
-
(2000)
Nature Genetics
, vol.25
, Issue.3
, pp. 338-342
-
-
Robertson, K.D.1
Ait-Si-Ali, S.2
Yokochi, T.3
Wade, P.A.4
Jones, P.L.5
Wolffe, A.P.6
-
46
-
-
0035873225
-
Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription
-
DOI 10.1093/emboj/20.10.2536
-
Fuks, F., Burgers, W. A., Godin, N., Kasai, M. & Kouzarides, T. Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcriptioN. EMBO J. 20, 2536-2544 (2001). (Pubitemid 32452872)
-
(2001)
EMBO Journal
, vol.20
, Issue.10
, pp. 2536-2544
-
-
Fuks, F.1
Burgers, W.A.2
Godin, N.3
Kasai, M.4
Kouzarides, T.5
-
47
-
-
0033988813
-
DNA methyltransferase Dnmt1 associates with histone deacetylase activity
-
DOI 10.1038/71750
-
Fuks, F., Burgers, W. A., Brehm, A., Hughes- Davies, L. & Kouzarides, T. DNA methyltransferase Dnmt1 associates with histone deacetylase activity. Nat. Genet. 24, 88-91 (2000). (Pubitemid 30041428)
-
(2000)
Nature Genetics
, vol.24
, Issue.1
, pp. 88-91
-
-
Fuks, F.1
Burgers, W.A.2
Brehm, A.3
Hughes-Davies, L.4
Kouzarides, T.5
-
48
-
-
0036607452
-
DNA methyltransferases get connected to chromatin
-
DOI 10.1016/S0168-9525(02)02667-7, PII S0168952502026677
-
Burgers, W. A., Fuks, F. & Kouzarides, T. DNA methyltransferases get connected to chromatiN. Trends Genet. 18, 275-277 (2002). (Pubitemid 34607108)
-
(2002)
Trends in Genetics
, vol.18
, Issue.6
, pp. 275-277
-
-
Burgers, W.A.1
Fuks, F.2
Kouzarides, T.3
-
49
-
-
0031792779
-
Identification and characterization of a family of mammalian methyl-CpG binding proteins
-
Hendrich, B. & Bird, A. Identification and characterization of a family of mammalian methyl-CpG binding proteins. Mol. Cell Biol. 18, 6538-6547 (1998). (Pubitemid 28500543)
-
(1998)
Molecular and Cellular Biology
, vol.18
, Issue.11
, pp. 6538-6547
-
-
Hendrich, B.1
Bird, A.2
-
50
-
-
0035394961
-
The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressor
-
DOI 10.1101/gad.198501
-
Prokhortchouk, A., et al. The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressoR. Genes DeV. 15, 1613-1618 (2001). (Pubitemid 32702582)
-
(2001)
Genes and Development
, vol.15
, Issue.13
, pp. 1613-1618
-
-
Prokhortchouk, A.1
Hendrich, B.2
Jorgensen, H.3
Ruzov, A.4
Wilm, M.5
Georgiev, G.6
Bird, A.7
Prokhortchouk, E.8
-
51
-
-
33645218438
-
A family of human zinc finger proteins that bind methylated DNA and repress transcription
-
Filion, G.J., et al. A family of human zinc finger proteins that bind methylated DNA and repress transcriptioN. Mol. Cell Biol. 26, 169-181 (2006).
-
(2006)
Mol. Cell Biol.
, vol.26
, pp. 169-181
-
-
Filion, G.J.1
-
52
-
-
0033973587
-
Active repression of methylated genes by the chromosomal protein MBD1
-
DOI 10.1128/MCB.20.4.1394-1406.2000
-
Ng, H. H., Jeppesen, P. & Bird, A. Active repression of methylated genes by the chromosomal protein MBD1. Mol. Cell Biol. 20, 1394-1406 (2000). (Pubitemid 30069259)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.4
, pp. 1394-1406
-
-
Ng, H.-H.1
Jeppesen, P.2
Bird, A.3
-
53
-
-
0037591867
-
Methyl-CpG binding domain 1 (MBD1) interacts with the Suv39h1-HP1 heterochromatic complex for DNA methylation-based transcriptional repression
-
DOI 10.1074/jbc.M302283200
-
Fujita, N., et al. Methyl-CpG binding domain 1 (MBD1) interacts with the Suv39h1-HP1 heterochromatic complex for DNA methylationbased transcriptional repressioN. J. Biol. Chem. 278, 24132-24138 (2003). (Pubitemid 36830249)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.26
, pp. 24132-24138
-
-
Fujita, N.1
Watanabe, S.2
Ichimura, T.3
Tsuruzoe, S.4
Shinkai, Y.5
Tachibana, M.6
Chiba, T.7
Nakao, M.8
-
54
-
-
0038412822
-
The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase
-
DOI 10.1093/nar/gkg332
-
Fuks, F., Hurd, P. J., Deplus, R. & Kouzarides, T. The DNA methyltransferases associate with HP1 and the SUv39H1 histone methyltransferasE. Nucleic Acids Res. 31, 2305-2312 (2003). (Pubitemid 37442098)
-
(2003)
Nucleic Acids Research
, vol.31
, Issue.9
, pp. 2305-2312
-
-
Fuks, F.1
Hurd, P.J.2
Deplus, R.3
Kouzarides, T.4
-
55
-
-
33749032436
-
A profile of methyl-CpG binding domain protein occupancy of hypermethylated promoter CpG islands of tumor suppressor genes in human cancer
-
DOI 10.1158/0008-5472.CAN-06-1932
-
Lopez-Serra, L., et al. A profile of methyl-CpG binding domain protein occupancy of hypermethylated promoter CpG islands of tumor suppressor genes in human canceR. Cancer Res. 66, 8342-8346 (2006). (Pubitemid 44449141)
-
(2006)
Cancer Research
, vol.66
, Issue.17
, pp. 8342-8346
-
-
Lopez-Serra, L.1
Ballestar, E.2
Fraga, M.F.3
Alaminos, M.4
Setien, F.5
Esteller, M.6
-
56
-
-
33644853802
-
Histone modifications: Signalling receptors and potential elements of a heritable epigenetic code
-
DOI 10.1016/j.gde.2006.02.015, PII S0959437X06000372, Chromosomes and Expression Mechanisms
-
Nightingale, K. P., O'Neill, L. P. & Turner, B. M. Histone modifications: signalling receptors and potential elements of a heritable epigenetic codE. CurR. OpiN. Genet. DeV. 16, 125-136 (2006). (Pubitemid 43376058)
-
(2006)
Current Opinion in Genetics and Development
, vol.16
, Issue.2
, pp. 125-136
-
-
Nightingale, K.P.1
O'Neill, L.P.2
Turner, B.M.3
-
57
-
-
0034912742
-
Histone acetyltransferases
-
DOI 10.1146/annurev.biochem.70.1.81
-
Roth, S. Y., Denu, J. M. & Allis, C. D. Histone acetyltransferases. Annu. ReV. Biochem. 70, 81-120 (2001). (Pubitemid 32662206)
-
(2001)
Annual Review of Biochemistry
, vol.70
, pp. 81-120
-
-
Roth, S.Y.1
Denu, J.M.2
Allis, C.D.3
-
58
-
-
0344407016
-
Histone deacetylases: Unique players in shaping the epigenetic histone code
-
Thiagalingam, S., et al. Histone deacetylases: unique players in shaping the epigenetic histone codE. AnN. NY Acad. ScI. 983, 84-100 (2003). (Pubitemid 36399322)
-
(2003)
Annals of the New York Academy of Sciences
, vol.983
, pp. 84-100
-
-
Thiagalingam, S.1
Cheng, K.-H.2
Lee, H.J.3
Mineva, N.4
Thiagalingam, A.5
Ponte, J.F.6
-
59
-
-
77949714263
-
SB939, a novel potent and orally active histone deacetylase inhibitor with high tumor exposure and efficacy in mouse models of colorectal cancer
-
Novotny-Diermayr, V., et al. SB939, a novel potent and orally active histone deacetylase inhibitor with high tumor exposure and efficacy in mouse models of colorectal canceR. Mol. Cancer TheR. 9, 642-652 (2010).
-
(2010)
Mol. Cancer TheR.
, vol.9
, pp. 642-652
-
-
Novotny-Diermayr, V.1
-
60
-
-
33947513027
-
Regulation of histone methylation by demethylimination and demethylation
-
DOI 10.1038/nrm2143, PII NRM2143
-
Klose, R. J. & Zhang, Y. Regulation of histone methylation by demethylimination and demethylatioN. Nat. ReV. Mol. Cell Biol. 8, 307-318 (2007). (Pubitemid 46474659)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.4
, pp. 307-318
-
-
Klose, R.J.1
Zhang, Y.2
-
61
-
-
20844450998
-
Arginine methylation: An emerging regulator of protein function
-
DOI 10.1016/j.molcel.2005.04.003, PII S1097276505012475
-
Bedford, M. T. & Richard, S. Arginine methylation an emerging regulator of protein functioN. Mol. Cell 18, 263-272 (2005). (Pubitemid 41350532)
-
(2005)
Molecular Cell
, vol.18
, Issue.3
, pp. 263-272
-
-
Bedford, M.T.1
Richard, S.2
-
62
-
-
25444520791
-
Effector proteins for methylated histones: An expanding family
-
Daniel, J. A., Pray-Grant, M. G. & Grant, P. A. Effector proteins for methylated histones: an expanding family. Cell Cycle 4, 919-926 (2005). (Pubitemid 41359758)
-
(2005)
Cell Cycle
, vol.4
, Issue.7
, pp. 919-926
-
-
Daniel, J.A.1
Pray-Grant, M.G.2
Grant, P.A.3
-
63
-
-
21744457108
-
Global histone modification patterns predict risk of prostate cancer recurrence
-
DOI 10.1038/nature03672
-
Seligson, D.B., et al. Global histone modification patterns predict risk of prostate cancer recurrencE. Nature 435, 1262-1266 (2005). (Pubitemid 40943093)
-
(2005)
Nature
, vol.435
, Issue.7046
, pp. 1262-1266
-
-
Seligson, D.B.1
Horvath, S.2
Shi, T.3
Yu, H.4
Tze, S.5
Grunstein, M.6
Kurdistani, S.K.7
-
64
-
-
72849148472
-
Global levels of histone modifications predict prostate cancer recurrence
-
Ellinger, J., et al. Global levels of histone modifications predict prostate cancer recurrencE. Prostate 70, 61-69 (2010).
-
(2010)
Prostate
, vol.70
, pp. 61-69
-
-
Ellinger, J.1
-
65
-
-
4644262388
-
Potentiation of androgen receptor transcriptional activity by inhibition of histone deacetylation - Rescue of transcriptionally compromised mutants
-
DOI 10.1677/joe.0.1820377
-
Korkmaz, C. G., Fronsdal, K., Zhang, Y., Lorenzo, P. I. & Saatcioglu, F. Potentiation of androgen receptor transcriptional activity by inhibition of histone deacetylation-rescue of transcriptionally compromised mutants. J. Endocrinol. 182, 377-389 (2004). (Pubitemid 39276206)
-
(2004)
Journal of Endocrinology
, vol.182
, Issue.3
, pp. 377-389
-
-
Korkmaz, C.G.1
Fronsdal, K.2
Zhang, Y.3
Lorenzo, P.I.4
Saatcioglu, F.5
-
66
-
-
0034617058
-
P300 and p300/cAMP-response element-binding protein-associated factor acetylate the androgen receptor at sites governing hormone-dependent transactivation
-
DOI 10.1074/jbc.M000660200
-
Fu, M., et al. p300 and p300/cAMP-response element-binding protein-associated factor acetylate the androgen receptor at sites governing hormone-dependent transactivatioN. J. Biol. Chem. 275, 20853-20860 (2000). (Pubitemid 30457679)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.27
, pp. 20853-20860
-
-
Fu, M.1
Wang, C.2
Reutens, A.T.3
Wang, J.4
Angeletti, R.H.5
Siconolfi-Baez, L.6
Ogryzko, V.7
Avantaggiati, M.-L.8
Pestell, R.G.9
-
67
-
-
2642662483
-
The histone acetylase PCAF is a nuclear receptor coactivator
-
Blanco, J.C., et al. The histone acetylase PCAF is a nuclear receptor coactivatoR. Genes DeV. 12, 1638-1651 (1998). (Pubitemid 28299515)
-
(1998)
Genes and Development
, vol.12
, Issue.11
, pp. 1638-1651
-
-
Blanco, J.C.G.1
Minucci, S.2
Lu, J.3
Yang, X.-J.4
Walker, K.K.5
Chen, H.6
Evans, R.M.7
Nakatani, Y.8
Ozato, K.9
-
68
-
-
0030768745
-
Steroid receptor coactivator-1 is a histone acetyltransferase
-
DOI 10.1038/38304
-
Spencer, T.E., et al. Steroid receptor coactivator-1 is a histone acetyltransferasE. Nature 389, 194-198 (1997). (Pubitemid 27400603)
-
(1997)
Nature
, vol.389
, Issue.6647
, pp. 194-198
-
-
Spencer, T.E.1
Jenster, G.2
Burcin, M.M.3
Allis, C.D.4
Zhou, J.5
Mizzen, C.A.6
McKenna, N.J.7
Onate, S.A.8
Tsai, S.Y.9
Tsai, M.-J.10
O'Malley, B.W.11
-
69
-
-
0037135566
-
Tip60 and histone deacetylase 1 regulate androgen receptor activity through changes to the acetylation status of the receptor
-
DOI 10.1074/jbc.M203423200
-
Gaughan, L., Logan, I. R., Cook, S., Neal, D. E. & Robson, C. N. Tip60 and histone deacetylase 1 regulate androgen receptor activity through changes to the acetylation status of the receptoR. J. Biol. Chem. 277, 25904-25913 (2002). (Pubitemid 34967070)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.29
, pp. 25904-25913
-
-
Gaughan, L.1
Logan, I.R.2
Cook, S.3
Neal, D.E.4
Robson, C.N.5
-
70
-
-
0036208492
-
Formation of the androgen receptor transcription complex
-
DOI 10.1016/S1097-2765(02)00471-9
-
Shang, Y., Myers, M. & Brown, M. Formation of the androgen receptor transcription complex. Mol. Cell 9, 601-610 (2002). (Pubitemid 34273790)
-
(2002)
Molecular Cell
, vol.9
, Issue.3
, pp. 601-610
-
-
Shang, Y.1
Myers, M.2
Brown, M.3
-
71
-
-
0030953186
-
Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase
-
DOI 10.1016/S0092-8674(00)80218-4
-
Nagy, L., et al. Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylasE. Cell 89, 373-380 (1997). (Pubitemid 27220882)
-
(1997)
Cell
, vol.89
, Issue.3
, pp. 373-380
-
-
Nagy, L.1
Kao, H.-Y.2
Chakravarti, D.3
Lin, R.J.4
Hassig, C.A.5
Ayer, D.E.6
Schreiber, S.L.7
Evans, R.M.8
-
72
-
-
34547451766
-
Sirtuin 1 is required for antagonist-induced transcriptional repression of androgen-responsive genes by the androgen receptor
-
DOI 10.1210/me.2006-0467
-
Dai, Y., et al. Sirt1 is required for antagonistinduced transcriptional repression of androgenresponsive genes by the androgen receptoR. Mol. Endocrinol. 21, 1807-1821 (2007). (Pubitemid 47173793)
-
(2007)
Molecular Endocrinology
, vol.21
, Issue.8
, pp. 1807-1821
-
-
Dai, Y.1
Ngo, D.2
Forman, L.W.3
Qin, D.C.4
Jacob, J.5
Faller, D.V.6
-
73
-
-
59149089556
-
Histone deacetylases are required for androgen receptor function in hormone-sensitive and castrate-resistant prostate cancer
-
Welsbie, D.S., et al. Histone deacetylases are required for androgen receptor function in hormone-sensitive and castrate-resistant prostate canceR. Cancer Res. 69, 958-966 (2009).
-
(2009)
Cancer Res.
, vol.69
, pp. 958-966
-
-
Welsbie, D.S.1
-
74
-
-
45849103492
-
Recurrent gene fusions in prostate cancer
-
Kumar-Sinha, C., Tomlins, S. A. & Chinnaiyan, A. M. Recurrent gene fusions in prostate canceR. Nat. ReV. Cancer 8, 497-511 (2008).
-
(2008)
Nat. ReV. Cancer
, vol.8
, pp. 497-511
-
-
Kumar-Sinha, C.1
Tomlins, S.A.2
Chinnaiyan, A.M.3
-
75
-
-
11144332565
-
Histone demethylation mediated by the nuclear amine oxidase homolog LSD1
-
DOI 10.1016/j.cell.2004.12.012, PII S0092867404011997
-
Shi, Y., et al. Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. Cell 119, 941-953 (2004). (Pubitemid 40037608)
-
(2004)
Cell
, vol.119
, Issue.7
, pp. 941-953
-
-
Shi, Y.1
Lan, F.2
Matson, C.3
Mulligan, P.4
Whetstine, J.R.5
Cole, P.A.6
Casero, R.A.7
Shi, Y.8
-
76
-
-
24144462170
-
LSD1 demethylates repressive histone marks to promote androgen-receptor- dependent transcription
-
DOI 10.1038/nature04020, PII N04020
-
Metzger, E., et al. LSD1 demethylates repressive histone marks to promote androgen-receptordependent transcriptioN. Nature 437, 436-439 (2005). (Pubitemid 41613508)
-
(2005)
Nature
, vol.437
, Issue.7057
, pp. 436-439
-
-
Metzger, E.1
Wissmann, M.2
Yin, N.3
Muller, J.M.4
Schneider, R.5
Peters, A.H.F.M.6
Gunther, T.7
Buettner, R.8
Schule, R.9
-
77
-
-
33845762289
-
Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostate cancer recurrence
-
DOI 10.1158/0008-5472.CAN-06-1570
-
Kahl, P., et al. Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostate cancer recurrencE. Cancer Res. 66, 11341-11347 (2006). (Pubitemid 46009965)
-
(2006)
Cancer Research
, vol.66
, Issue.23
, pp. 11341-11347
-
-
Kahl, P.1
Gullotti, L.2
Heukamp, L.C.3
Wolf, S.4
Friedrichs, N.5
Vorreuther, R.6
Solleder, G.7
Bastian, P.J.8
Ellinger, J.9
Metzger, E.10
Schule, R.11
Buettner, R.12
-
78
-
-
33847392500
-
Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression
-
Wissmann, M., et al. Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expressioN. Nat. Cell Biol. 9, 347-353 (2007).
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 347-353
-
-
Wissmann, M.1
-
79
-
-
0030922630
-
Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeres
-
DOI 10.1093/emboj/16.11.3219
-
Laible, G., et al. Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeres. EMBO J. 16, 3219-3232 (1997). (Pubitemid 27234960)
-
(1997)
EMBO Journal
, vol.16
, Issue.11
, pp. 3219-3232
-
-
Laible, G.1
Wolf, A.2
Dorn, R.3
Reuter, G.4
Nislow, C.5
Lebersorger, A.6
Popkin, D.7
Pillus, L.8
Jenuwein, T.9
-
80
-
-
32844459336
-
The Polycomb group protein EZH2 directly controls DNA methylation
-
DOI 10.1038/nature04431, PII NATURE04431
-
Vire, E., et al. The Polycomb group protein EZH2 directly controls DNA methylatioN. Nature 439, 871-874 (2006). (Pubitemid 43255707)
-
(2006)
Nature
, vol.439
, Issue.7078
, pp. 871-874
-
-
Vire, E.1
Brenner, C.2
Deplus, R.3
Blanchon, L.4
Fraga, M.5
Didelot, C.6
Morey, L.7
Van Eynde, A.8
Bernard, D.9
Vanderwinden, J.-M.10
Bollen, M.11
Esteller, M.12
Di Croce, L.13
De Launoit, Y.14
Fuks, F.15
-
81
-
-
33644765912
-
Expression of enhancer of zeste homologue 2 is significantly associated with increased tumor cell proliferation and is a marker of aggressive breast cancer
-
DOI 10.1158/1078-0432.CCR-05-1533
-
Collett, K., et al. Expression of enhancer of zeste homologue 2 is significantly associated with increased tumor cell proliferation and is a marker of aggressive breast canceR. CliN. Cancer Res. 12, 1168-1174 (2006). (Pubitemid 43342505)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.4
, pp. 1168-1174
-
-
Collett, K.1
Eide, G.E.2
Arnes, J.3
Stefansson, I.M.4
Eide, J.5
Braaten, A.6
Aas, T.7
Otte, A.P.8
Akslen, L.A.9
-
82
-
-
33644822360
-
EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast
-
DOI 10.1200/JCO.2005.01.5180
-
Bachmann, I.M., et al. EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast. J. CliN. Oncol. 24, 268-273 (2006). (Pubitemid 46622055)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.2
, pp. 268-273
-
-
Bachmann, I.M.1
Halvorsen, O.J.2
Collett, K.3
Stefansson, I.M.4
Straume, O.5
Haukaas, S.A.6
Salvesen, H.B.7
Otte, A.P.8
Akslen, L.A.9
-
83
-
-
18644382388
-
The polycomb group protein EZH2 is involved in progression of prostate cancer
-
Varambally, S., et al. The polycomb group protein EZH2 is involved in progression of prostate canceR. Nature 419, 624-629 (2002).
-
(2002)
Nature
, vol.419
, pp. 624-629
-
-
Varambally, S.1
-
84
-
-
77954572735
-
Long noncoding RNA as modular scaffold of histone modification complexes
-
Tsai, M.C., et al. Long noncoding RNA as modular scaffold of histone modification complexes. Science 329, 689-693 (2010).
-
(2010)
Science
, vol.329
, pp. 689-693
-
-
Tsai, M.C.1
-
85
-
-
40749090479
-
Widespread deregulation of microRNA expression in human prostate cancer
-
DOI 10.1038/sj.onc.1210809, PII 1210809
-
Ozen, M., Creighton, C. J., Ozdemir, M. & Ittmann, M. widespread deregulation of microRNA expression in human prostate canceR. Oncogene 27, 1788-1793 (2008). (Pubitemid 351380263)
-
(2008)
Oncogene
, vol.27
, Issue.12
, pp. 1788-1793
-
-
Ozen, M.1
Creighton, C.J.2
Ozdemir, M.3
Ittmann, M.4
-
86
-
-
51049123624
-
Genomic profiling of microRNA and messenger RNA reveals deregulated microRNA expression in prostate cancer
-
Ambs, S., et al. Genomic profiling of microRNA and messenger RNA reveals deregulated microRNA expression in prostate canceR. Cancer Res. 68, 6162-6170 (2008).
-
(2008)
Cancer Res.
, vol.68
, pp. 6162-6170
-
-
Ambs, S.1
-
87
-
-
65549083102
-
The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2
-
Friedman, J.M., et al. The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2. Cancer Res. 69, 2623-2629 (2009).
-
(2009)
Cancer Res.
, vol.69
, pp. 2623-2629
-
-
Friedman, J.M.1
-
88
-
-
58149239686
-
Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer
-
Varambally, S., et al. Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in canceR. Science 322, 1695-1699 (2008).
-
(2008)
Science
, vol.322
, pp. 1695-1699
-
-
Varambally, S.1
-
89
-
-
77955590791
-
MiR-193b is an epigenetically regulated putative tumor suppressor in prostate cancer
-
Rauhala, H.E., et al. miR-193b is an epigenetically regulated putative tumor suppressor in prostate canceR. Int. J. Cancer 127, 1363-1372 (2010).
-
(2010)
Int. J. Cancer
, vol.127
, pp. 1363-1372
-
-
Rauhala, H.E.1
-
90
-
-
51649083501
-
A microRNA DNA methylation signature for human cancer metastasis
-
Lujambio, A., et al. A microRNA DNA methylation signature for human cancer metastasis. Proc. Natl Acad. ScI. USA 105, 13556-13561 (2008).
-
(2008)
Proc. Natl Acad. ScI. USA
, vol.105
, pp. 13556-13561
-
-
Lujambio, A.1
-
91
-
-
33748451151
-
Anticancer activities of histone deacetylase inhibitors
-
DOI 10.1038/nrd2133, PII NRD2133
-
Bolden, J. E., Peart, M. J. & Johnstone, R. W. Anticancer activities of histone deacetylase inhibitors. Nat. ReV. Drug DiscoV. 5, 769-784 (2006). (Pubitemid 44348499)
-
(2006)
Nature Reviews Drug Discovery
, vol.5
, Issue.9
, pp. 769-784
-
-
Bolden, J.E.1
Peart, M.J.2
Johnstone, R.W.3
-
92
-
-
26444439216
-
Prospects: Histone deacetylase inhibitors
-
DOI 10.1002/jcb.20532
-
Dokmanovic, M. & Marks, P. A. Prospects: histone deacetylase inhibitors. J. Cell Biochem. 96, 293-304 (2005). (Pubitemid 41437862)
-
(2005)
Journal of Cellular Biochemistry
, vol.96
, Issue.2
, pp. 293-304
-
-
Dokmanovic, M.1
Marks, P.A.2
-
93
-
-
30344477367
-
Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
-
DOI 10.1038/nrc1779
-
Minucci, S. & Pelicci, P. G. Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for canceR. Nat. ReV. Cancer 6, 38-51 (2006). (Pubitemid 43054973)
-
(2006)
Nature Reviews Cancer
, vol.6
, Issue.1
, pp. 38-51
-
-
Minucci, S.1
Pelicci, P.G.2
-
94
-
-
34250872780
-
Multiple molecular pathways explain the anti-proliferative effect of valproic acid on prostate cancer cells in vitro and in vivo
-
DOI 10.1002/pros.20587
-
Shabbeer, S., et al. Multiple Molecular pathways explain the anti-proliferative effect of valproic acid on prostate cancer cells in vitro and in vivo. Prostate 67, 1099-1110 (2007). (Pubitemid 46983339)
-
(2007)
Prostate
, vol.67
, Issue.10
, pp. 1099-1110
-
-
Shabbeer, S.1
Kortenhorst, M.S.Q.2
Kachhap, S.3
Galloway, N.4
Rodriguez, R.5
Carducci, M.A.6
-
95
-
-
33746883106
-
Chronic administration of valproic acid inhibits prostate cancer cell growth in vitro and in vivo
-
DOI 10.1158/0008-5472.CAN-05-0487
-
Xia, Q., et al. Chronic administration of valproic acid inhibits prostate cancer cell growth in vitro and in vivo. Cancer Res. 66, 7237-7244 (2006). (Pubitemid 44197704)
-
(2006)
Cancer Research
, vol.66
, Issue.14
, pp. 7237-7244
-
-
Xia, Q.1
Sung, J.2
Chowdhury, W.3
Chen, C.-L.4
Hoti, N.5
Shabbeer, S.6
Carducci, M.7
Rodriguez, R.8
-
96
-
-
31544464120
-
Targeting tumor angiogenesis with histone deacetylase inhibitors: The hydroxamic acid derivative LBH589
-
DOI 10.1158/1078-0432.CCR-05-1132
-
Qian, D.Z., et al. Targeting tumor angiogenesis with histone deacetylase inhibitors: the hydroxamic acid derivative LBH589. CliN. Cancer Res. 12, 634-642 (2006). (Pubitemid 43166159)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.2
, pp. 634-642
-
-
Qian, D.Z.1
Kato, Y.2
Shabbeer, S.3
Wei, Y.4
Verheul, H.M.W.5
Salumbides, B.6
Sanni, T.7
Atadja, P.8
Pili, R.9
-
97
-
-
77951884767
-
A phase I study of oral panobinostat alone and in combination with docetaxel in patients with castration-resistant prostate cancer
-
Rathkopf, D., et al. A phase I study of oral panobinostat alone and in combination with docetaxel in patients with castration-resistant prostate canceR. Cancer ChemotheR. Pharmacol. 66, 181-189 (2010).
-
(2010)
Cancer ChemotheR. Pharmacol.
, vol.66
, pp. 181-189
-
-
Rathkopf, D.1
-
98
-
-
72249110437
-
Vorinostat in advanced prostate cancer patients progressing on prior chemotherapy (National Cancer Institute Trial 6862): trial results and interleukin-6 analysis: A study by the Department of Defense Prostate Cancer Clinical Trial Consortium and University of Chicago Phase 2 Consortium
-
Bradley, D., et al. vorinostat in advanced prostate cancer patients progressing on prior chemotherapy (National Cancer Institute Trial 6862): trial results and interleukin-6 analysis: a study by the Department of Defense Prostate Cancer Clinical Trial Consortium and University of Chicago Phase 2 Consortium. Cancer 115, 5541-5549 (2009).
-
(2009)
Cancer
, vol.115
, pp. 5541-5549
-
-
Bradley, D.1
-
99
-
-
0034665124
-
Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses the growth of prostate cancer cells in vitro and in vivo
-
Butler, L.M., et al. Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses the growth of prostate cancer cells in vitro and in vivo. Cancer Res. 60, 5165-5170 (2000).
-
(2000)
Cancer Res.
, vol.60
, pp. 5165-5170
-
-
Butler, L.M.1
-
100
-
-
33645125545
-
Mechanisms of cell death induced by histone deacetylase inhibitors in androgen receptor-positive prostate cancer cells
-
Rokhlin, O.W., et al. Mechanisms of cell death induced by histone deacetylase inhibitors in androgen receptor-positive prostate cancer cells. Mol. Cancer Res. 4, 113-123 (2006).
-
(2006)
Mol. Cancer Res.
, vol.4
, pp. 113-123
-
-
Rokhlin, O.W.1
-
101
-
-
33846839622
-
Suberoylanilide hydroxamic acid (vorinostat) represses androgen receptor expression and acts synergistically with an androgen receptor antagonist to inhibit prostate cancer cell proliferation
-
DOI 10.1158/1535-7163.MCT-06-0144
-
Marrocco, D.L., et al. Suberoylanilide hydroxamic acid (vorinostat) represses androgen receptor expression and acts synergistically with an androgen receptor antagonist to inhibit prostate cancer cell proliferatioN. Mol. Cancer TheR. 6, 51-60 (2007). (Pubitemid 46209918)
-
(2007)
Molecular Cancer Therapeutics
, vol.6
, Issue.1
, pp. 51-60
-
-
Marrocco, D.L.1
Tilley, W.D.2
Bianco-Miotto, T.3
Evdokiou, A.4
Scher, H.I.5
Rifkind, R.A.6
Marks, P.A.7
Richon, V.M.8
Butler, L.M.9
-
102
-
-
0028258610
-
FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties, and antitumor activity
-
Ueda, H., et al. FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. I. Taxonomy, fermentation, isolation, physicochemical and biological properties, and antitumor activity. J. Antibiot. (Tokyo) 47, 301-310 (1994). (Pubitemid 24106520)
-
(1994)
Journal of Antibiotics
, vol.47
, Issue.3
, pp. 301-310
-
-
Ueda, H.1
Nakajima, H.2
Hori, Y.3
Fujita, T.4
Nishimura, M.5
Goto, T.6
Okuhara, M.7
-
103
-
-
0028500561
-
Action of FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No.968, on Ha-ras transformed NIH3T3 cells
-
Ueda, H., Nakajima, H., Hori, Y., Goto, T. & Okuhara, M. Action of FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum no. 968, on Ha-ras transformed NIH3T3 cells. BioscI. Biotechnol. Biochem. 58, 1579-1583 (1994). (Pubitemid 2159869)
-
(1994)
Bioscience, Biotechnology and Biochemistry
, vol.58
, Issue.9
, pp. 1579-1583
-
-
Ueda, H.1
Nakajima, H.2
Hori, Y.3
Goto, T.4
Okuhara, M.5
-
104
-
-
70549105748
-
Phase II, two-stage, single-arm trial of the histone deacetylase inhibitor (HDACi) romidepsin in metastatic castration-resistant prostate cancer (CRPC)
-
Molife, L.R., et al. Phase II, two-stage, single-arm trial of the histone deacetylase inhibitor (HDACi) romidepsin in metastatic castration-resistant prostate cancer (CRPC). AnN. Oncol. 21, 109-113 (2010).
-
(2010)
AnN. Oncol.
, vol.21
, pp. 109-113
-
-
Molife, L.R.1
-
105
-
-
34547662889
-
Antitumor activity of the histone deacetylase inhibitor MS-275 in prostate cancer models
-
DOI 10.1002/pros.20611
-
Qian, D.Z., et al. Antitumor activity of the histone deacetylase inhibitor MS-275 in prostate cancer models. Prostate 67, 1182-1193 (2007). (Pubitemid 47221885)
-
(2007)
Prostate
, vol.67
, Issue.11
, pp. 1182-1193
-
-
Qian, D.Z.1
Wei, Y.-F.2
Wang, X.3
Kato, Y.4
Cheng, L.5
Pili, R.6
-
106
-
-
0242522928
-
Histone Deacetylase Inhibitors
-
DOI 10.1021/jm0303094
-
Miller, T. A., witter, D. J. & Belvedere, S. Histone deacetylase inhibitors. J. Med. Chem. 46, 5097-5116 (2003). (Pubitemid 37414179)
-
(2003)
Journal of Medicinal Chemistry
, vol.46
, Issue.24
, pp. 5097-5116
-
-
Miller, T.A.1
Witter, D.J.2
Belvedere, S.3
-
107
-
-
33749029926
-
Antitumor effects of a novel phenylbutyrate-based histone deacetylase inhibitor, (S)-HDAC-42, in prostate cancer
-
DOI 10.1158/1078-0432.CCR-06-0429
-
Kulp, S. K., Chen, C. S., wang, D. S. & Chen, C. Y. Antitumor effects of a novel phenylbutyrate-based histone deacetylase inhibitor, (S.)-HDAC-42, in prostate canceR. CliN. Cancer Res. 12, 5199-5206 (2006). (Pubitemid 44453349)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.17
, pp. 5199-5206
-
-
Kulp, S.K.1
Chen, C.-S.2
Wang, D.-S.3
Chen, C.-Y.4
Chen, C.-S.5
-
108
-
-
34347206854
-
Histone deacetylase inhibitors sensitize prostate cancer cells to agents that produce DNA double-strand breaks by targeting Ku70 acetylation
-
Chen, C.S., et al. Histone deacetylase inhibitors sensitize prostate cancer cells to agents that produce DNA double-strand breaks by targeting Ku70 acetylatioN. Cancer Res. 67, 5318-5327 (2007).
-
(2007)
Cancer Res.
, vol.67
, pp. 5318-5327
-
-
Chen, C.S.1
-
109
-
-
0000032126
-
Depudecin induces morphological reversion of transformed fibroblasts via the inhibition of histone deacetylase
-
DOI 10.1073/pnas.95.7.3356
-
Kwon, H. J., Owa, T., Hassig, C. A., Shimada, J. & Schreiber, S. L. Depudecin induces morphological reversion of transformed fibroblasts via the inhibition of histone deacetylasE. Proc. Natl Acad. ScI. USA 95, 3356-3361 (1998). (Pubitemid 28173131)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.7
, pp. 3356-3361
-
-
Kwon, H.J.1
Owa, T.2
Hassig, C.A.3
Shimada, J.4
Schreiber, S.L.5
-
110
-
-
77956246016
-
The histone deacetylase inhibitor MGCD0103 has both deacetylase and microtubule inhibitory activity
-
Chia, K., Beamish, H., Jafferi, K. & Gabrielli, B. The histone deacetylase inhibitor MGCD0103 has both deacetylase and microtubule inhibitory activity. Mol. Pharmacol. 78, 436-443 (2010).
-
(2010)
Mol. Pharmacol.
, vol.78
, pp. 436-443
-
-
Chia, K.1
Beamish, H.2
Jafferi, K.3
Gabrielli, B.4
-
111
-
-
77952168284
-
The histone deacetylase inhibitor MGCD0103 induces apoptosis in B-cell chronic lymphocytic leukemia cells through a mitochondria-mediated caspase activation cascade
-
El-Khoury, V., et al. The histone deacetylase inhibitor MGCD0103 induces apoptosis in B-cell chronic lymphocytic leukemia cells through a mitochondria-mediated caspase activation cascadE. Mol. Cancer TheR. 9, 1349-1360 (2010).
-
(2010)
Mol. Cancer TheR.
, vol.9
, pp. 1349-1360
-
-
El-Khoury, V.1
-
112
-
-
42249084230
-
MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity in vitro and in vivo
-
DOI 10.1158/1535-7163.MCT-07-2026
-
Fournel, M., et al. MGCD0103, a novel isotypeselective histone deacetylase inhibitor, has broad spectrum antitumor activity in vitro and in vivo. Mol. Cancer TheR. 7, 759-768 (2008). (Pubitemid 351551029)
-
(2008)
Molecular Cancer Therapeutics
, vol.7
, Issue.4
, pp. 759-768
-
-
Fournel, M.1
Bonfils, C.2
Hou, Y.3
Yan, P.T.4
Trachy-Bourget, M.-C.5
Kalita, A.6
Liu, J.7
Lu, A.-H.8
Zhou, N.Z.9
Robert, M.-F.10
Gillespie, J.11
Wang, J.J.12
Ste-Croix, H.13
Rahil, J.14
Lefebvre, S.15
Moradei, O.16
Delorme, D.17
MacLeod, A.R.18
Besterman, J.M.19
Li, Z.20
more..
-
113
-
-
12344272623
-
Histone deacetylase inhibitors differentially mediate apoptosis in prostate cancer cells
-
DOI 10.1002/pros.20140
-
Fronsdal, K. & Saatcioglu, F. Histone deacetylase inhibitors differentially mediate apoptosis in prostate cancer cells. Prostate 62, 299-306 (2005). (Pubitemid 40129069)
-
(2005)
Prostate
, vol.62
, Issue.3
, pp. 299-306
-
-
Fronsdal, K.1
Saatcioglu, F.2
-
114
-
-
0033822112
-
P21-dependent g(1)arrest with downregulation of cyclin D1 and upregulation of cyclin E by the histone deacetylase inhibitor FR901228
-
Sandor, V., et al. P21-dependent g(1)arrest with downregulation of cyclin D1 and upregulation of cyclin E by the histone deacetylase inhibitor FR901228. BR. J. Cancer 83, 817-825 (2000).
-
(2000)
BR. J. Cancer
, vol.83
, pp. 817-825
-
-
Sandor, V.1
-
115
-
-
0028267278
-
FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. III. Antitumor activities on experimental tumors in mice
-
Ueda, H., et al. FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. III. Antitumor activities on experimental tumors in micE. J. Antibiot. (Tokyo) 47, 315-323 (1994). (Pubitemid 24106522)
-
(1994)
Journal of Antibiotics
, vol.47
, Issue.3
, pp. 315-323
-
-
Ueda, H.1
Manda, T.2
Matsumoto, S.3
Mukumoto, S.4
Nishigaki, F.5
Kawamura, I.6
Shimomura, K.7
-
116
-
-
0034671618
-
Activation of MHC class I, II, and CD40 gene expression by histone deacetylase inhibitors
-
Magner, W.J., et al. Activation of MHC class I, II, and CD40 gene expression by histone deacetylase inhibitors. J. Immunol. 165, 7017-7024 (2000). (Pubitemid 32001174)
-
(2000)
Journal of Immunology
, vol.165
, Issue.12
, pp. 7017-7024
-
-
Magner, W.J.1
Kazim, A.L.2
Stewart, C.3
Romano, M.A.4
Catalano, G.5
Grande, C.6
Keiser, N.7
Santaniello, F.8
Tomasi, T.B.9
-
117
-
-
85047699941
-
Histone deacetylases inhibitors as anti-angiogenic agents altering vascular endothelial growth factor signaling
-
DOI 10.1038/sj/onc/1205108
-
Deroanne, C.F., et al. Histone deacetylases inhibitors as anti-angiogenic agents altering vascular endothelial growth factor signaling. Oncogene 21, 427-436 (2002). (Pubitemid 34123805)
-
(2002)
Oncogene
, vol.21
, Issue.3
, pp. 427-436
-
-
Deroanne, C.F.1
Bonjean, K.2
Servotte, S.3
Devy, L.4
Colige, A.5
Clausse, N.6
Blacher, S.7
Verdin, E.8
Foidart, J.-M.9
Nusgens, B.V.10
Castronovo, V.11
-
118
-
-
0034548836
-
Up-regulation of costimulatory/adhesion molecules by histone deacetylase inhibitors in acute myeloid leukemia cells
-
Maeda, T., Towatari, M., Kosugi, H. & Saito, H. Up-regulation of costimulatory/adhesion molecules by histone deacetylase inhibitors in acute myeloid leukemia cells. Blood 96, 3847-3856 (2000).
-
(2000)
Blood
, vol.96
, pp. 3847-3856
-
-
Maeda, T.1
Towatari, M.2
Kosugi, H.3
Saito, H.4
-
119
-
-
0343484254
-
Regulation of E2F1 activity by acetylation
-
Martinez-Balbas, M. A., Bauer, U. M., Nielsen, S. J., Brehm, A. & Kouzarides, T. Regulation of E2F1 activity by acetylatioN. EMBO J. 19, 662-671 (2000). (Pubitemid 30093739)
-
(2000)
EMBO Journal
, vol.19
, Issue.4
, pp. 662-671
-
-
Martinez-Balbas, M.A.1
Bauer, U.-M.2
Nielsen, S.J.3
Brehm, A.4
Kouzarides, T.5
-
120
-
-
0030797585
-
Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain
-
DOI 10.1016/S0092-8674(00)80521-8
-
Gu, W. & Roeder, R. G. Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domaiN. Cell 90, 595-606 (1997). (Pubitemid 27357952)
-
(1997)
Cell
, vol.90
, Issue.4
, pp. 595-606
-
-
Gu, W.1
Roeder, R.G.2
-
121
-
-
12244251445
-
Stat3 dimerization regulated by reversible acetylation of a single lysine residue
-
DOI 10.1126/science.1105166
-
Yuan, Z. L., Guan, Y. J., Chatterjee, D. & Chin, Y. E. Stat3 dimerization regulated by reversible acetylation of a single lysine residuE. Science 307, 269-273 (2005). (Pubitemid 40116244)
-
(2005)
Science
, vol.307
, Issue.5707
, pp. 269-273
-
-
Yuan, Z.-L.1
Guan, Y.-J.2
Chatterjee, D.3
Chin, Y.E.4
-
122
-
-
0035979737
-
Duration of nuclear NF-κB action regulated by reversible acetylation
-
DOI 10.1126/science.1062374
-
Chen, L., Fischle, W., verdin, E. & Greene, W. C. Duration of nuclear NF-kappaB action regulated by reversible acetylatioN. Science 293, 1653-1657 (2001). (Pubitemid 32807844)
-
(2001)
Science
, vol.293
, Issue.5535
, pp. 1653-1657
-
-
Chen, L.-F.1
Fischle, W.2
Verdin, E.3
Greene, W.C.4
-
123
-
-
0038142184
-
Differential regulation of E2F1 apoptotic target genes in response to DNA damage
-
DOI 10.1038/ncb998
-
Pediconi, N., et al. Differential regulation of E2F1 apoptotic target genes in response to DNA damagE. Nat. Cell Biol. 5, 552-558 (2003). (Pubitemid 36781090)
-
(2003)
Nature Cell Biology
, vol.5
, Issue.6
, pp. 552-558
-
-
Pediconi, N.1
Ianari, A.2
Costanzo, A.3
Belloni, L.4
Gallo, R.5
Cimino, L.6
Porcellini, A.7
Screpanti, I.8
Balsano, C.9
Alesse, E.10
Gulino, A.11
Levrero, M.12
-
124
-
-
18244408596
-
DNA damage-dependent acetylation of p73 dictates the selective activation of apoptotic target genes
-
DOI 10.1016/S1097-2765(02)00431-8
-
Costanzo, A., et al. DNA damage-dependent acetylation of p73 dictates the selective activation of apoptotic target genes. Mol. Cell 9, 175-186 (2002). (Pubitemid 34127781)
-
(2002)
Molecular Cell
, vol.9
, Issue.1
, pp. 175-186
-
-
Costanzo, A.1
Merlo, P.2
Pediconi, N.3
Fulco, M.4
Sartorelli, V.5
Cole, P.A.6
Fontemaggi, G.7
Fanciulli, M.8
Schiltz, L.9
Blandino, G.10
Balsano, C.11
Levrero, M.12
-
125
-
-
33744539154
-
Apoptosis signal-regulating kinase 1 is a direct target of E2F1 and contributes to histone deacetylase inhibitor-induced apoptosis through positive feedback regulation of E2F1 apoptotic activity
-
DOI 10.1074/jbc.M512719200
-
Tan, J., et al. Apoptosis signal-regulating kinase 1 is a direct target of E2F1 and contributes to histone deacetylase inhibitor-induced apoptosis through positive feedback regulation of E2F1 apoptotic activity. J. Biol. Chem. 281, 10508-10515 (2006). (Pubitemid 43864590)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.15
, pp. 10508-10515
-
-
Tan, J.1
Zhuang, L.2
Jiang, X.3
Yang, K.K.4
Karuturi, K.M.5
Yu, Q.6
-
126
-
-
18644365597
-
Histone deacetylase inhibitors differentially stabilize acetylated p53 and induce cell cycle arrest or apoptosis in prostate cancer cells
-
DOI 10.1038/sj.cdd.4401581
-
Roy, S., Packman, K., Jeffrey, R. & Tenniswood, M. Histone deacetylase inhibitors differentially stabilize acetylated p53 and induce cell cycle arrest or apoptosis in prostate cancer cells. Cell Death DiffeR. 12, 482-491 (2005). (Pubitemid 40662846)
-
(2005)
Cell Death and Differentiation
, vol.12
, Issue.5
, pp. 482-491
-
-
Roy, S.1
Packman, K.2
Jeffrey, R.3
Tenniswood, M.4
-
127
-
-
0033912223
-
Adenovirus E1B 55-kilodalton oncoprotein inhibits p53 acetylation by PCAF
-
DOI 10.1128/MCB.20.15.5540-5553.2000
-
Liu, Y., Colosimo, A. L., Yang, X. J. & Liao, D. Adenovirus E1B 55-kilodalton oncoprotein inhibits p53 acetylation by PCAF. Mol. Cell Biol. 20, 5540-5553 (2000). (Pubitemid 30482890)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.15
, pp. 5540-5553
-
-
Liu, Y.1
Colosimo, A.L.2
Yang, X.-J.3
Liao, D.4
-
128
-
-
33847779059
-
Site-specific acetylation of p53 directs selective transcription complex assembly
-
DOI 10.1074/jbc.M609588200
-
Roy, S. & Tenniswood, M. Site-specific acetylation of p53 directs selective transcription complex assembly. J. Biol. Chem. 282, 4765-4771 (2007). (Pubitemid 47100922)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.7
, pp. 4765-4771
-
-
Roy, S.1
Tenniswood, M.2
-
129
-
-
12144286529
-
Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis
-
DOI 10.1016/S1097-2765(04)00094-2, PII S1097276504000942
-
Cohen, H.Y., et al. Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis. Mol. Cell 13, 627-638 (2004). (Pubitemid 38368121)
-
(2004)
Molecular Cell
, vol.13
, Issue.5
, pp. 627-638
-
-
Cohen, H.Y.1
Lavu, S.2
Bitterman, K.J.3
Hekking, B.4
Imahiyerobo, T.A.5
Miller, C.6
Frye, R.7
Ploegh, H.8
Kessler, B.M.9
Sinclair, D.A.10
-
130
-
-
0018860957
-
Cellular differentiation, cytidine analogs and DNA methylation
-
Jones, P. A. & Taylor, S. M. Cellular differentiation, cytidine analogs and DNA methylatioN. Cell 20, 85-93 (1980). (Pubitemid 10117303)
-
(1980)
Cell
, vol.20
, Issue.1
, pp. 85-93
-
-
Jones, P.A.1
Taylor, S.M.2
-
131
-
-
0021830501
-
The irreversible binding of azacytosine-containing DNA fragments to bacterial DNA(cytosine-5)methyltransferases
-
Friedman, S. The irreversible binding of azacytosine-containing DNA fragments to bacterial DNA(cytosine-5)methyltransferases. J. Biol. Chem. 260, 5698-5705 (1985). (Pubitemid 15001131)
-
(1985)
Journal of Biological Chemistry
, vol.260
, Issue.9
, pp. 5698-5705
-
-
Friedman, S.1
-
132
-
-
0000418476
-
Covalent bond formation between a DNA-cytosine methyltransferase and DNA containing 5-azacytosine
-
DOI 10.1073/pnas.81.22.6993
-
Santi, D. V., Norment, A. & Garrett, C. E. Covalent bond formation between a DNA-cytosine methyltransferase and DNA containing 5-azacytosinE. Proc. Natl Acad. ScI. USA 81, 6993-6997 (1984). (Pubitemid 15216684)
-
(1984)
Proceedings of the National Academy of Sciences of the United States of America
, vol.81
, Issue.22
, pp. 6993-6997
-
-
Santi, D.V.1
Norment, A.2
Garrett, C.E.3
-
133
-
-
0028151343
-
Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation
-
Juttermann, R., Li, E. & Jaenisch, R. Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylatioN. Proc. Natl Acad. ScI. USA 91, 11797-11801 (1994).
-
(1994)
Proc. Natl Acad. ScI. USA
, vol.91
, pp. 11797-11801
-
-
Juttermann, R.1
Li, E.2
Jaenisch, R.3
-
134
-
-
33644856123
-
Epigenetic therapy of cancer: Past, present and future
-
Yoo, C. B. & Jones, P. A. Epigenetic therapy of cancer: past, present and futurE. Nat. ReV. Drug DiscoV. 5, 37-50 (2006).
-
(2006)
Nat. ReV. Drug DiscoV.
, vol.5
, pp. 37-50
-
-
Yoo, C.B.1
Jones, P.A.2
-
135
-
-
0035843169
-
Inactivation of the apoptosis effector Apaf-1 in malignant melanoma
-
DOI 10.1038/35051606
-
Soengas, M.S., et al. Inactivation of the apoptosis effector Apaf-1 in malignant melanoma. Nature 409, 207-211 (2001). (Pubitemid 32144287)
-
(2001)
Nature
, vol.409
, Issue.6817
, pp. 207-211
-
-
Soengas, M.S.1
Capodieci, P.2
Polsky, D.3
Mora, J.4
Esteller, M.5
Opitz-Araya, X.6
McCombie, R.7
Herman, J.G.8
Gerald, W.L.9
Lazebnik, Y.A.10
Cordon-Cardo, C.11
Lowe, S.W.12
-
137
-
-
0036861629
-
DNA methyltransferase inhibitors-state of the art
-
Goffin, J. & Eisenhauer, E. DNA methyltransferase inhibitors-state of the art. AnN. Oncol. 13, 1699-1716 (2002).
-
(2002)
AnN. Oncol.
, vol.13
, pp. 1699-1716
-
-
Goffin, J.1
Eisenhauer, E.2
-
138
-
-
0034932724
-
The role of epigenetic modifications in retinoic acid receptor β2 gene expression in human prostate cancers
-
Nakayama, T., et al. The role of epigenetic modifications in retinoic acid receptor beta2 gene expression in human prostate cancers. Lab. Invest. 81, 1049-1057 (2001). (Pubitemid 32645980)
-
(2001)
Laboratory Investigation
, vol.81
, Issue.7
, pp. 1049-1057
-
-
Nakayama, T.1
Watanabe, M.2
Yamanaka, M.3
Hirokawa, Y.4
Suzuki, H.5
Ito, H.6
Yatani, R.7
Shiraishi, T.8
-
139
-
-
0035152120
-
GSTP1 CpG island hypermethylation is responsible for the absence of GSTP1 expression in human prostate cancer cells
-
Lin, X., et al. GSTP1 CpG island hypermethylation is responsible for the absence of GSTP1 expression in human prostate cancer cells. Am. J. Pathol. 159, 1815-1826 (2001). (Pubitemid 33062524)
-
(2001)
American Journal of Pathology
, vol.159
, Issue.5
, pp. 1815-1826
-
-
Lin, X.1
Tascilar, M.2
Lee, W.-H.3
Vles, W.J.4
Lee, B.H.5
Veeraswamy, R.6
Asgari, K.7
Freije, D.8
Van Rees, B.9
Gage, W.R.10
Bova, G.S.11
Isaacs, W.B.12
Brooks, J.D.13
Deweese, T.L.14
De Marzo, A.M.15
Nelson, W.G.16
-
140
-
-
0031964055
-
Inhibition of DNA methylation by 5-Aza-2'-deoxycytidine suppresses the growth of human tumor cell lines
-
Bender, C. M., Pao, M. M. & Jones, P. A. Inhibition of DNA methylation by 5-aza-2'-deoxycytidine suppresses the growth of human tumor cell lines. Cancer Res. 58, 95-101 (1998). (Pubitemid 28027723)
-
(1998)
Cancer Research
, vol.58
, Issue.1
, pp. 95-101
-
-
Bender, C.M.1
Pao, M.M.2
Jones, P.A.3
-
141
-
-
17444452612
-
Low-dose 5-Aza-2'-deoxycytidine, a DNA hypomethylating agent, for the treatment of high-risk myelodysplastic syndrome: A multicenter phase II study in elderly patients
-
Wijermans, P., et al. Low-dose 5-aza-2'- deoxycytidine, a DNA hypomethylating agent, for the treatment of high-risk myelodysplastic syndrome: a multicenter phase II study in elderly patients. J. CliN. Oncol. 18, 956-962 (2000). (Pubitemid 30123770)
-
(2000)
Journal of Clinical Oncology
, vol.18
, Issue.5
, pp. 956-962
-
-
Wijermans, P.1
Lubbert, M.2
Verhoef, G.3
Bosly, A.4
Ravoet, C.5
Andre, M.6
Ferrant, A.7
-
142
-
-
10744233452
-
Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in hematopoietic malignancies
-
Issa, J.P., et al. Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in hematopoietic malignancies. Blood 103, 1635-1640 (2004).
-
(2004)
Blood
, vol.103
, pp. 1635-1640
-
-
Issa, J.P.1
-
143
-
-
21244449980
-
Evaluation of a 7-day continuous intravenous infusion of decitabine: Inhibition of promoter-specific and global genomic DNA methylation
-
DOI 10.1200/JCO.2005.06.118
-
Samlowski, W.E., et al. Evaluation of a 7-day continuous intravenous infusion of decitabine: inhibition of promoter-specific and global genomic DNA methylatioN. J. CliN. Oncol. 23, 3897-3905 (2005). (Pubitemid 46218692)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.17
, pp. 3897-3905
-
-
Samlowski, W.E.1
Leachman, S.A.2
Wade, M.3
Cassidy, P.4
Porter-Gill, P.5
Busby, L.6
Wheeler, R.7
Boucher, K.8
Fitzpatrick, F.9
Jones, D.A.10
Karpf, A.R.11
-
144
-
-
0036794950
-
Phase II trial of cisplatin plus decitabine, a new DNA hypomethylating agent, in patients with advanced squamous cell carcinoma of the cervix
-
DOI 10.1097/00000421-200210000-00015
-
Pohlmann, P., et al. Phase II trial of cisplatin plus decitabine, a new DNA hypomethylating agent, in patients with advanced squamous cell carcinoma of the cervix. Am. J. CliN. Oncol. 25, 496-501 (2002). (Pubitemid 35154957)
-
(2002)
American Journal of Clinical Oncology: Cancer Clinical Trials
, vol.25
, Issue.5
, pp. 496-501
-
-
Pohlmann, P.1
DiLeone, L.P.2
Cancella, A.I.3
Caldas, A.P.F.4
Dal Lago, L.5
Campos Jr., O.6
Monego, E.7
Rivoire, W.8
Schwartsmann, G.9
-
145
-
-
0031001563
-
Mutagenicity of 5-aza-2'-deoxycytidine is mediated by the mammalian DNA methyltransferase
-
Jackson-Grusby, L., Laird, P. W., Magge, S. N., Moeller, B. J. & Jaenisch, R. Mutagenicity of 5-aza-2'-deoxycytidine is mediated by the mammalian DNA methyltransferasE. Proc. Natl Acad. ScI. USA 94, 4681-4685 (1997).
-
(1997)
Proc. Natl Acad. ScI. USA
, vol.94
, pp. 4681-4685
-
-
Jackson-Grusby, L.1
Laird, P.W.2
Magge, S.N.3
Moeller, B.J.4
Jaenisch, R.5
-
146
-
-
0024402515
-
In vitro neoplastic progression of rat tracheal epithelial cells transformed by diverse carcinogens
-
Walker, C. & Nettesheim, P. In vitro neoplastic progression of rat tracheal epithelial cells transformed by diverse carcinogens. Cancer Res. 49, 4427-4430 (1989). (Pubitemid 19208338)
-
(1989)
Cancer Research
, vol.49
, Issue.16
, pp. 4427-4430
-
-
Walker, C.1
Nettesheim, P.2
-
147
-
-
0015692518
-
Distribution of kinase and deaminase of 1-beta-D-arabinofuranosylcytosine in tissues of man and mouse
-
Ho, D. H. Distribution of kinase and deaminase of 1-beta-D- arabinofuranosylcytosine in tissues of man and mousE. Cancer Res. 33, 2816-2820 (1973).
-
(1973)
Cancer Res.
, vol.33
, pp. 2816-2820
-
-
Ho, D.H.1
-
148
-
-
2642531973
-
Epigenetics in human disease and prospects for epigenetic therapy
-
DOI 10.1038/nature02625
-
Egger, G., Liang, G., Aparicio, A. & Jones, P. A. Epigenetics in human disease and prospects for epigenetic therapy. Nature 429, 457-463 (2004). (Pubitemid 38715140)
-
(2004)
Nature
, vol.429
, Issue.6990
, pp. 457-463
-
-
Egger, G.1
Liang, G.2
Aparicio, A.3
Jones, P.A.4
-
149
-
-
81055125529
-
Azacitidine favorably modulates PSA kinetics correlating with plasma DNA LINE-1 hypomethylation in men with chemonaive castration-resistant prostate cancer
-
doi:10.1016/j.urolonc.2009.09.015.
-
Sonpavde, G., et al. Azacitidine favorably modulates PSA kinetics correlating with plasma DNA LINE-1 hypomethylation in men with chemonaive castration-resistant prostate canceR. Urol. Oncol. doi:10.1016/ j.urolonc.2009.09.015.
-
Urol. Oncol.
-
-
Sonpavde, G.1
-
150
-
-
0031945210
-
A phase II study of 5-aza-2'deoxycytidine (decitabine) in hormone independent metastatic (D2) prostate cancer
-
Thibault, A., et al. A phase II study of 5-aza-2'deoxycytidine (decitabine) in hormone independent metastatic (D2) prostate canceR. Tumori 84, 87-89 (1998). (Pubitemid 28221854)
-
(1998)
Tumori
, vol.84
, Issue.1
, pp. 87-89
-
-
Thibault, A.1
Figg, W.D.2
Bergan, R.C.3
Lush, R.M.4
Myers, C.E.5
Tompkins, A.6
Reed, E.7
Samid, D.8
-
151
-
-
0037420191
-
Inhibition of DNA methylation and reactivation of silenced genes by zebularine
-
Cheng, J.C., et al. Inhibition of DNA methylation and reactivation of silenced genes by zebularinE. J. Natl Cancer Inst. 95, 399-409 (2003). (Pubitemid 36395260)
-
(2003)
Journal of the National Cancer Institute
, vol.95
, Issue.5
, pp. 399-409
-
-
Cheng, J.C.1
Matsen, C.B.2
Gonzales, F.A.3
Ye, W.4
Greer, S.5
Marquez, V.E.6
Jones, P.A.7
Selker, E.U.8
-
152
-
-
1642499364
-
Continuous Zebularine Treatment Effectively Sustains Demethylation in Human Bladder Cancer Cells
-
DOI 10.1128/MCB.24.3.1270-1278.2004
-
Cheng, J.C., et al. Continuous zebularine treatment effectively sustains demethylation in human bladder cancer cells. Mol. Cell Biol. 24, 1270-1278 (2004). (Pubitemid 38112188)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.3
, pp. 1270-1278
-
-
Cheng, J.C.1
Weisenberger, D.J.2
Gonzales, F.A.3
Liang, G.4
Xu, G.-L.5
Hu, Y.-G.6
Marquez, V.E.7
Jones, P.A.8
-
153
-
-
0035893767
-
Reversal of GSTP1 CpG island hypermethylation and reactivation of π-class glutathione S-transferase (GSTP1) expression in human prostate cancer cells by treatment with procainamide
-
Lin, X., et al. Reversal of GSTP1 CpG island hypermethylation and reactivation of pi-class glutathione S.-transferase (GSTP1) expression in human prostate cancer cells by treatment with procainamidE. Cancer Res. 61, 8611-8616 (2001). (Pubitemid 34013864)
-
(2001)
Cancer Research
, vol.61
, Issue.24
, pp. 8611-8616
-
-
Lin, X.1
Asgari, K.2
Putzi, M.J.3
Gage, W.R.4
Yu, X.5
Cornblatt, B.S.6
Kumar, A.7
Piantadosi, S.8
DeWeese, T.L.9
De Marzo, A.M.10
Nelson, W.G.11
-
154
-
-
0041939756
-
Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells
-
Villar-Garea, A., Fraga, M. F., Espada, J. & Esteller, M. Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells. Cancer Res. 63, 4984-4989 (2003). (Pubitemid 37022635)
-
(2003)
Cancer Research
, vol.63
, Issue.16
, pp. 4984-4989
-
-
Villar-Garea, A.1
Fraga, M.F.2
Espada, J.3
Esteller, M.4
-
155
-
-
12444297637
-
Phase I and pharmacologic study of the human DNA methyltransferase antisense oligodeoxynucleotide MG98 given as a 21-day continuous infusion every 4 weeks
-
DOI 10.1023/A:1022976528441
-
Davis, A.J., et al. Phase I and pharmacologic study of the human DNA methyltransferase antisense oligodeoxynucleotide MG98 given as a 21-day continuous infusion every 4 weeks. Invest. New Drugs 21, 85-97 (2003). (Pubitemid 36628488)
-
(2003)
Investigational New Drugs
, vol.21
, Issue.1
, pp. 85-97
-
-
Davis, A.J.1
Gelmon, K.A.2
Siu, L.L.3
Moore, M.J.4
Britten, C.D.5
Mistry, N.6
Klamut, H.7
D'Aloisio, S.8
MacLean, M.9
Wainman, N.10
Ayers, D.11
Firby, P.12
Besterman, J.M.13
Reid, G.K.14
Eisenhauer, E.A.15
-
156
-
-
33646595937
-
Phase II trial of DNA methyltransferase 1 inhibition with the antisense oligonucleotide MG98 in patients with metastatic renal carcinoma: A National Cancer Institute of Canada Clinical Trials Group investigational new drug study
-
DOI 10.1007/s10637-006-5938-1
-
Winquist, E., et al. Phase II trial of DNA methyltransferase 1 inhibition with the antisense oligonucleotide MG98 in patients with metastatic renal carcinoma: a National Cancer Institute of Canada Clinical Trials Group investigational new drug study. Invest. New Drugs 24, 159-167 (2006). (Pubitemid 43723908)
-
(2006)
Investigational New Drugs
, vol.24
, Issue.2
, pp. 159-167
-
-
Winquist, E.1
Knox, J.2
Ayoub, J.-P.3
Wood, L.4
Wainman, N.5
Reid, G.K.6
Pearce, L.7
Shah, A.8
Eisenhauer, E.9
-
157
-
-
31044451642
-
Depletion of DNA methyltransferase 1 and/or DNA methyltransferase 3b mediates growth arrest and apoptosis in lung and esophageal cancer and malignant pleural mesothelioma cells
-
Kassis, E.S., et al. Depletion of DNA methyltransferase 1 and/or DNA methyltransferase 3b mediates growth arrest and apoptosis in lung and esophageal cancer and malignant pleural mesothelioma cells. J. Thorac Cardiovasc. Surg. 131, 298-306 (2006).
-
(2006)
J. Thorac Cardiovasc. Surg.
, vol.131
, pp. 298-306
-
-
Kassis, E.S.1
-
158
-
-
22244435605
-
Epigenetic reactivation of tumor suppressor genes by a novel small-molecule inhibitor of human DNA methyltransferases
-
DOI 10.1158/0008-5472.CAN-04-2957
-
Brueckner, B., et al. Epigenetic reactivation of tumor suppressor genes by a novel smallmolecule inhibitor of human DNA methyltransferases. Cancer Res. 65, 6305-6311 (2005). (Pubitemid 40994416)
-
(2005)
Cancer Research
, vol.65
, Issue.14
, pp. 6305-6311
-
-
Brueckner, B.1
Boy, R.G.2
Siedlecki, P.3
Musch, T.4
Kliem, H.C.5
Zielenkiewicz, P.6
Suhai, S.7
Wiessler, M.8
Lyko, F.9
-
159
-
-
27644597195
-
Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2′-deoxycytidine
-
DOI 10.1158/1535-7163.MCT-05-0172
-
Chuang, J.C., et al. Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2'-deoxycytidinE. Mol. Cancer TheR. 4, 1515-1520 (2005). (Pubitemid 41556433)
-
(2005)
Molecular Cancer Therapeutics
, vol.4
, Issue.10
, pp. 1515-1520
-
-
Chuang, J.C.1
Yoo, C.B.2
Kwan, J.M.3
Li, T.W.H.4
Liang, G.5
Yang, A.S.6
Jones, P.A.7
-
160
-
-
33645086120
-
Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines
-
Stresemann, C., Brueckner, B., Musch, T., Stopper, H. & Lyko, F. Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines. Cancer Res. 66, 2794-2800 (2006).
-
(2006)
Cancer Res.
, vol.66
, pp. 2794-2800
-
-
Stresemann, C.1
Brueckner, B.2
Musch, T.3
Stopper, H.4
Lyko, F.5
-
161
-
-
33644846509
-
Epigenetic gene silencing in cancer - A mechanism for early oncogenic pathway addiction?
-
DOI 10.1038/nrc1799, PII N1799
-
Baylin, S. B. & Ohm, J. E. Epigenetic gene silencing in cancer-a mechanism for early oncogenic pathway addiction? Nat. ReV. Cancer 6, 107-116 (2006). (Pubitemid 43361543)
-
(2006)
Nature Reviews Cancer
, vol.6
, Issue.2
, pp. 107-116
-
-
Baylin, S.B.1
Ohm, J.E.2
-
162
-
-
29244469466
-
The epigenetic progenitor origin of human cancer
-
DOI 10.1038/nrg1748
-
Feinberg, A. P., Ohlsson, R. & Henikoff, S. The epigenetic progenitor origin of human canceR. Nat. ReV. Genet. 7, 21-33 (2006). (Pubitemid 41828945)
-
(2006)
Nature Reviews Genetics
, vol.7
, Issue.1
, pp. 21-33
-
-
Feinberg, A.P.1
Ohlsson, R.2
Henikoff, S.3
-
163
-
-
0035684270
-
Preneoplastic prostate lesions: An opportunity for prostate cancer prevention
-
Nelson, W.G., et al. Preneoplastic prostate lesions: an opportunity for prostate cancer preventioN. AnN. NY Acad. ScI. 952, 135-144 (2001). (Pubitemid 34060016)
-
(2001)
Annals of the New York Academy of Sciences
, vol.952
, pp. 135-144
-
-
Nelson, W.G.1
De Marzo, A.M.2
Deweese, T.L.3
Lin, X.4
Brooks, J.D.5
Putzi, M.J.6
Nelson, C.P.7
Groopman, J.D.8
Kensler, T.W.9
-
164
-
-
0029001154
-
Suppression of intestinal neoplasia by DNA hypomethylation
-
Laird, P.W., et al. Suppression of intestinal neoplasia by DNA hypomethylatioN. Cell 81, 197-205 (1995).
-
(1995)
Cell
, vol.81
, pp. 197-205
-
-
Laird, P.W.1
-
165
-
-
31544458225
-
Inhibition of DNA methyltransferase activity prevents tumorigenesis in a mouse model of prostate cancer
-
DOI 10.1158/0008-5472.CAN-05-2020
-
McCabe, M.T., et al. Inhibition of DNA methyltransferase activity prevents tumorigenesis in a mouse model of prostate canceR. Cancer Res. 66, 385-392 (2006). (Pubitemid 43166046)
-
(2006)
Cancer Research
, vol.66
, Issue.1
, pp. 385-392
-
-
McCabe, M.T.1
Low, J.A.2
Daignault, S.3
Imperiale, M.J.4
Wojno, K.J.5
Day, M.L.6
-
166
-
-
33845969839
-
Dietary polyphenols may affect DNA methylation
-
Fang, M., Chen, D. & Yang, C. S. Dietary polyphenols may affect DNA methylatioN. J. NutR. 137, 223S-228S (2007). (Pubitemid 46052885)
-
(2007)
Journal of Nutrition
, vol.137
, Issue.1
-
-
Fang, M.1
Chen, D.2
Yang, C.S.3
-
167
-
-
77953649001
-
Green tea and prostate cancer: From bench to clinic
-
Pandey, M. & Gupta, S. Green tea and prostate cancer: from bench to clinic. Front. BioscI. (Elite Ed.) 1, 13-25 (2009).
-
(2009)
Front. BioscI. (Elite Ed.)
, vol.1
, pp. 13-25
-
-
Pandey, M.1
Gupta, S.2
-
168
-
-
74549216395
-
Genistein reverses hypermethylation and induces active histone modifications in tumor suppressor gene B-Cell translocation gene 3 in prostate cancer
-
Majid, S., et al. Genistein reverses hypermethylation and induces active histone modifications in tumor suppressor gene B-Cell translocation gene 3 in prostate canceR. Cancer 116, 66-76 (2010).
-
(2010)
Cancer
, vol.116
, pp. 66-76
-
-
Majid, S.1
-
169
-
-
33846217828
-
Dual action on promoter demethylation and chromatin by an isothiocyanate restored GSTP1 silenced in prostate cancer
-
DOI 10.1002/mc.20258
-
Wang, L.G., et al. Dual action on promoter demethylation and chromatin by an isothiocyanate restored GSTP1 silenced in prostate canceR. Mol. Carcinog. 46, 24-31 (2007). (Pubitemid 46095230)
-
(2007)
Molecular Carcinogenesis
, vol.46
, Issue.1
, pp. 24-31
-
-
Wang, L.G.1
Beklemisheva, A.2
Liu, X.M.3
Ferrari, A.C.4
Feng, J.5
Chiao, J.W.6
-
170
-
-
4344649449
-
Ingestion of an isothiocyanate metabolite from cruciferous vegetables inhibits growth of human prostate cancer cell xenografts by apoptosis and cell cycle arrest
-
DOI 10.1093/carcin/bgh136
-
Chiao, J.W., et al. Ingestion of an isothiocyanate metabolite from cruciferous vegetables inhibits growth of human prostate cancer cell xenografts by apoptosis and cell cycle arrest. Carcinogenesis 25, 1403-1408 (2004). (Pubitemid 39172078)
-
(2004)
Carcinogenesis
, vol.25
, Issue.8
, pp. 1403-1408
-
-
Chiao, J.W.1
Wu, H.2
Ramaswamy, G.3
Conaway, C.C.4
Chung, F.-L.5
Wang, L.6
Liu, D.7
-
171
-
-
17644423471
-
Caspase-dependent apoptosis induction by phenethyl isothiocyanate, a cruciferous vegetable-derived cancer chemopreventive agent, is mediated by Bak and Bax
-
DOI 10.1158/1078-0432.CCR-04-1545
-
Xiao, D., et al. Caspase-dependent apoptosis induction by phenethyl isothiocyanate, a cruciferous vegetable-derived cancer chemopreventive agent, is mediated by Bak and Bax. CliN. Cancer Res. 11, 2670-2679 (2005). (Pubitemid 40569468)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.7
, pp. 2670-2679
-
-
Xiao, D.1
Zeng, Y.2
Choi, S.3
Lew, K.L.4
Nelson, J.B.5
Singh, S.V.6
-
172
-
-
31544454684
-
Combined inhibitory effects of curcumin and phenethyl isothiocyanate on the growth of human PC-3 prostate xenografts in immunodeficient mice
-
DOI 10.1158/0008-5472.CAN-05-2708
-
Khor, T.O., et al. Combined inhibitory effects of curcumin and phenethyl isothiocyanate on the growth of human PC-3 prostate xenografts in immunodeficient micE. Cancer Res. 66, 613-621 (2006). (Pubitemid 43165919)
-
(2006)
Cancer Research
, vol.66
, Issue.2
, pp. 613-621
-
-
Khor, T.O.1
Keum, Y.-S.2
Lin, W.3
Kim, J.-H.4
Hu, R.5
Shen, G.6
Xu, C.7
Gopalakrishnan, A.8
Reddy, B.9
Zheng, X.10
Conney, A.H.11
Kong, A.-N.T.12
-
173
-
-
0035997978
-
Curcumin suppresses activation of NF-kappaB and AP-1 induced by phorbol ester in cultured human promyelocytic leukemia cells
-
Han, S. S., Keum, Y. S., Seo, H. J. & Surh, Y. J. Curcumin suppresses activation of NF-kappaB and AP-1 induced by phorbol ester in cultured human promyelocytic leukemia cells. J. Biochem. Mol. Biol. 35, 337-342 (2002).
-
(2002)
J. Biochem. Mol. Biol.
, vol.35
, pp. 337-342
-
-
Han, S.S.1
Keum, Y.S.2
Seo, H.J.3
Surh, Y.J.4
-
174
-
-
34247850953
-
Involvement of Bcl-2 family members, phosphatidylinositol 3'-kinase/AKT and mitochondrial p53 in curcumin (diferulolylmethane)-induced apoptosis in prostate cancer
-
Shankar, S. & Srivastava, R. K. Involvement of Bcl-2 family members, phosphatidylinositol 3'-kinase/AKT and mitochondrial p53 in curcumin (diferulolylmethane)-induced apoptosis in prostate canceR. Int. J. Oncol. 30, 905-918 (2007).
-
(2007)
Int. J. Oncol.
, vol.30
, pp. 905-918
-
-
Shankar, S.1
Srivastava, R.K.2
-
175
-
-
1542426626
-
Curcumin confers radiosensitizing effect in prostate cancer cell line PC-3
-
DOI 10.1038/sj.onc.1207284
-
Chendil, D., Ranga, R. S., Meigooni, D., Sathishkumar, S. & Ahmed, M. M. Curcumin confers radiosensitizing effect in prostate cancer cell line PC-3. Oncogene 23, 1599-1607 (2004). (Pubitemid 38406523)
-
(2004)
Oncogene
, vol.23
, Issue.8
, pp. 1599-1607
-
-
Chendil, D.1
Ranga, R.S.2
Meigooni, D.3
Sathishkumar, S.4
Ahmed, M.M.5
-
176
-
-
0032948005
-
Synergy of demethylation and histone deacetylase inhibition in the re- expression of genes silenced in cancer
-
DOI 10.1038/5047
-
Cameron, E. E., Bachman, K. E., Myohanen, S., Herman, J. G. & Baylin, S. B. Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in canceR. Nat. Genet. 21, 103-107 (1999). (Pubitemid 29036293)
-
(1999)
Nature Genetics
, vol.21
, Issue.1
, pp. 103-107
-
-
Cameron, E.E.1
Bachman, K.E.2
Myohanen, S.3
Herman, J.G.4
Baylin, S.B.5
-
177
-
-
0034528599
-
Epigenetic regulation of androgen receptor gene expression in human prostate cancers
-
Nakayama, T., et al. Epigenetic regulation of androgen receptor gene expression in human prostate cancers. Lab. Invest. 80, 1789-1796 (2000). (Pubitemid 32012748)
-
(2000)
Laboratory Investigation
, vol.80
, Issue.12
, pp. 1789-1796
-
-
Nakayama, T.1
Watanabe, M.2
Suzuki, H.3
Toyota, M.4
Sekita, N.5
Hirokawa, Y.6
Mizokami, A.7
Ito, H.8
Yatani, R.9
Shiraishi, T.10
-
178
-
-
0032403081
-
Methylation of the androgen receptor promoter CpG island is associated with loss of androgen receptor expression in prostate cancer cells
-
Jarrard, D.F., et al. Methylation of the androgen receptor promoter CpG island is associated with loss of androgen expression in prostate cancer cells. Cancer Res. 58, 5310-5314 (1998). (Pubitemid 28551106)
-
(1998)
Cancer Research
, vol.58
, Issue.23
, pp. 5310-5314
-
-
Jarrard, D.F.1
Kinoshita, H.2
Shi, Y.3
Sandefur, C.4
Hoff, D.5
Meisner, L.F.6
Chang, C.7
Herman, J.G.8
Isaacs, W.B.9
Nassif, N.10
-
179
-
-
4644259264
-
Enhancement of xenograft tumor radiosensitivity by the histone deacetylase inhibitor MS-275 and correlation with histone hyperacetylation
-
DOI 10.1158/1078-0432.CCR-04-0537
-
Camphausen, K., Scott, T., Sproull, M. & Tofilon, P. J. Enhancement of xenograft tumor radiosensitivity by the histone deacetylase inhibitor MS-275 and correlation with histone hyperacetylatioN. CliN. Cancer Res. 10, 6066-6071 (2004). (Pubitemid 39302609)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.18
, pp. 6066-6071
-
-
Camphausen, K.1
Scott, T.2
Sproull, M.3
Tofilon, P.J.4
-
180
-
-
33749626553
-
Peroxisome proliferatoractivated receptor gamma regulates E-cadherin expression and inhibits growth and invasion of prostate cancer
-
Annicotte, J.S., et al. Peroxisome proliferatoractivated receptor gamma regulates E-cadherin expression and inhibits growth and invasion of prostate canceR. Mol. Cell Biol. 26, 7561-7574 (2006).
-
(2006)
Mol. Cell Biol.
, vol.26
, pp. 7561-7574
-
-
Annicotte, J.S.1
-
181
-
-
33646517941
-
SAHA-sensitized prostate cancer cells to TNFalpha-related apoptosis-inducing ligand (TRAIL): Mechanisms leading to synergistic apoptosis
-
Lakshmikanthan, V., Kaddour-Djebbar, I., Lewis, R. W. & Kumar, M. V. SAHA-sensitized prostate cancer cells to TNFalpha-related apoptosis-inducing ligand (TRAIL): mechanisms leading to synergistic apoptosis. Int. J. Cancer 119, 221-228 (2006).
-
(2006)
Int. J. Cancer
, vol.119
, pp. 221-228
-
-
Lakshmikanthan, V.1
Kaddour-Djebbar, I.2
Lewis, R.W.3
Kumar, M.V.4
-
182
-
-
33847302895
-
Histone deacetylase inhibitors enhance Ad5- TRAIL killing of TRAIL-resistant prostate tumor cells through increased caspase-2 activity
-
VanOosten, R. L., Earel, J. K. Jr & Griffith, T. S. Histone deacetylase inhibitors enhance Ad5- TRAIL killing of TRAIL-resistant prostate tumor cells through increased caspase-2 activity. Apoptosis 12, 561-571 (2007).
-
(2007)
Apoptosis
, vol.12
, pp. 561-571
-
-
VanOosten, R.L.1
Earel Jr., J.K.2
Griffith, T.S.3
-
183
-
-
14844345670
-
Depsipeptide (FR901228) enhances the cytotoxic activity of TRAIL by redistributing TRAIL receptor to membrane lipid rafts
-
DOI 10.1016/j.ymthe.2004.12.008, PII S1525001604015746
-
Vanoosten, R. L., Moore, J. M., Ludwig, A. T. & Griffith, T. S. Depsipeptide (FR901228) enhances the cytotoxic activity of TRAIL by redistributing TRAIL receptor to membrane lipid rafts. Mol. TheR. 11, 542-552 (2005). (Pubitemid 40353112)
-
(2005)
Molecular Therapy
, vol.11
, Issue.4
, pp. 542-552
-
-
VanOosten, R.L.1
Moore, J.M.2
Ludwig, A.T.3
Griffith, T.S.4
-
184
-
-
34249949312
-
Low concentrations of the histone deacetylase inhibitor, depsipeptide, enhance the effects of gemcitabine and docetaxel in hormone refractory prostate cancer cells
-
Kanzaki, M., et al. Low concentrations of the histone deacetylase inhibitor, depsipeptide, enhance the effects of gemcitabine and docetaxel in hormone refractory prostate cancer cells. Oncol. Rep. 17, 761-767 (2007).
-
(2007)
Oncol. Rep.
, vol.17
, pp. 761-767
-
-
Kanzaki, M.1
-
185
-
-
73449090440
-
Induction of bicalutamide sensitivity in prostate cancer cells by an epigenetic Puralpha-mediated decrease in androgen receptor levels
-
Liu, X., Gomez-Pinillos, A., Johnson, E. M. & Ferrari, A. C. Induction of bicalutamide sensitivity in prostate cancer cells by an epigenetic Puralpha-mediated decrease in androgen receptor levels. Prostate 70, 179-189 (2010).
-
(2010)
Prostate
, vol.70
, pp. 179-189
-
-
Liu, X.1
Gomez-Pinillos, A.2
Johnson, E.M.3
Ferrari, A.C.4
-
186
-
-
63449112539
-
Synergy of 5-aza-2'- deoxycytidine (DAC) and paclitaxel in both androgen-dependent and -independent prostate cancer cell lines
-
Shang, D., et al. Synergy of 5-aza-2'- deoxycytidine (DAC) and paclitaxel in both androgen-dependent and -independent prostate cancer cell lines. Cancer Lett. 278, 82-87 (2009).
-
(2009)
Cancer Lett.
, vol.278
, pp. 82-87
-
-
Shang, D.1
-
187
-
-
7744235007
-
Enhanced sensitivity of prostate cancer DU145 cells to cisplatinum by 5-aza-2'-deoxycytidine
-
Fang, X., Zheng, C., Liu, Z., Ekman, P. & Xu, D. Enhanced sensitivity of prostate cancer DU145 cells to cisplatinum by 5-aza-2'-deoxycytidinE. Oncol. Rep. 12, 523-526 (2004).
-
(2004)
Oncol. Rep.
, vol.12
, pp. 523-526
-
-
Fang, X.1
Zheng, C.2
Liu, Z.3
Ekman, P.4
Xu, D.5
-
188
-
-
34247506661
-
5-Aza-2′-deoxycytidine delays androgen-independent disease and improves survival in the transgenic adenocarcinoma of the mouse prostate mouse model of prostate cancer
-
DOI 10.1158/1078-0432.CCR-06-2381
-
Zorn, C.S., et al. 5-Aza-2'-deoxycytidine delays androgen-independent disease and improves survival in the transgenic adenocarcinoma of the mouse prostate mouse model of prostate canceR. CliN. Cancer Res. 13, 2136-2143 (2007). (Pubitemid 46649883)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.7
, pp. 2136-2143
-
-
Zorn, C.S.1
Wojno, K.J.2
McCabe, M.T.3
Kuefer, R.4
Gschwend, J.E.5
Day, M.L.6
-
189
-
-
77955975878
-
5-Azacitidine restores and amplifies the bicalutamide response on preclinical models of androgen receptor expressing or deficient prostate tumors
-
Gravina, G.L., et al. 5-Azacitidine restores and amplifies the bicalutamide response on preclinical models of androgen receptor expressing or deficient prostate tumors. Prostate 70, 1166-1178 (2010).
-
(2010)
Prostate
, vol.70
, pp. 1166-1178
-
-
Gravina, G.L.1
-
190
-
-
0032827113
-
Roles of cell division and gene transcription in the methylation of CpG islands
-
Bender, C.M., et al. Roles of cell division and gene transcription in the methylation of CpG islands. Mol. Cell Biol. 19, 6690-6698 (1999). (Pubitemid 29441853)
-
(1999)
Molecular and Cellular Biology
, vol.19
, Issue.10
, pp. 6690-6698
-
-
Bender, C.M.1
Gonzalgo, M.L.2
Gonzales, F.A.3
Nguyen, C.T.4
Robertson, K.D.5
Jones, P.A.6
-
191
-
-
38849165455
-
CpG island hypermethylation profile in the serum of men with clinically localized and hormone refractory metastatic prostate cancer
-
discussion 534-535
-
Bastian, P.J., et al. CpG island hypermethylation profile in the serum of men with clinically localized and hormone refractory metastatic prostate canceR. J. Urol. 179, 529-534; discussion 534-535 (2008).
-
(2008)
J. Urol.
, vol.179
, pp. 529-534
-
-
Bastian, P.J.1
-
192
-
-
35649020283
-
MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B
-
DOI 10.1073/pnas.0707628104
-
Fabbri, M., et al. MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. Proc. Natl Acad. ScI. USA 104, 15805-15810 (2007). (Pubitemid 350035380)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.40
, pp. 15805-15810
-
-
Fabbri, M.1
Garzon, R.2
Cimmino, A.3
Liu, Z.4
Zanesi, N.5
Callegari, E.6
Liu, S.7
Alder, H.8
Costinean, S.9
Fernandez-Cymering, C.10
Volinia, S.11
Guler, G.12
Morrison, C.D.13
Chan, K.K.14
Marcucci, G.15
Calin, G.A.16
Huebner, K.17
Croce, C.M.18
-
193
-
-
33847763576
-
Genetic unmasking of an epigenetically silenced microRNA in human cancer cells
-
DOI 10.1158/0008-5472.CAN-06-4218
-
Lujambio, A., et al. Genetic unmasking of an epigenetically silenced microRNA in human cancer cells. Cancer Res. 67, 1424-1429 (2007). (Pubitemid 46383366)
-
(2007)
Cancer Research
, vol.67
, Issue.4
, pp. 1424-1429
-
-
Lujambio, A.1
Ropero, S.2
Ballestar, E.3
Fraga, M.F.4
Cerrato, C.5
Setien, F.6
Casado, S.7
Suarez-Gauthier, A.8
Sanchez-Cespedes, M.9
Gitt, A.10
Spiteri, I.11
Das, P.P.12
Caldas, C.13
Miska, E.14
Esteller, M.15
-
194
-
-
42349099338
-
A requirement for DICER to maintain full promoter CpG island hypermethylation in human cancer cells
-
DOI 10.1158/0008-5472.CAN-07-6405
-
Ting, A.H., et al. A requirement for DICER to maintain full promoter CpG island hypermethylation in human cancer cells. Cancer Res. 68, 2570-2575 (2008). (Pubitemid 351556253)
-
(2008)
Cancer Research
, vol.68
, Issue.8
, pp. 2570-2575
-
-
Ting, A.H.1
Suzuki, H.2
Cope, L.3
Schuebel, K.E.4
Lee, B.H.5
Toyota, M.6
Imai, K.7
Shinomura, Y.8
Tokino, T.9
Baylin, S.B.10
-
195
-
-
4344705410
-
Small interfering RNA-induced transcriptional gene silencing in human cells
-
DOI 10.1126/science.1101372
-
Morris, K. V., Chan, S. W., Jacobsen, S. E. & Looney, D. J. Small interfering RNA-induced transcriptional gene silencing in human cells. Science 305, 1289-1292 (2004). (Pubitemid 39129233)
-
(2004)
Science
, vol.305
, Issue.5688
, pp. 1289-1292
-
-
Morris, K.V.1
Chan, S.W.-L.2
Jacobsen, S.E.3
Looney, D.J.4
-
196
-
-
33644768137
-
PDLIM4 repression by hypermethylation as a potential biomarker for prostate cancer
-
DOI 10.1158/1078-0432.CCR-05-2072
-
Vanaja, D.K., et al. PDLIM4 repression by hypermethylation as a potential biomarker for prostate canceR. CliN. Cancer Res. 12, 1128-1136 (2006). (Pubitemid 43342500)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.4
, pp. 1128-1136
-
-
Vanaja, D.K.1
Ballman, K.V.2
Morlan, B.W.3
Cheville, J.C.4
Neumann, R.M.5
Lieber, M.M.6
Tindall, D.J.7
Young, C.Y.F.8
-
197
-
-
0037709969
-
Methylation status of uPA promoter as a molecular mechanism regulating prostate cancer invasion and growth in vitro and in vivo
-
DOI 10.1096/fj.02-0973com
-
Pakneshan, P., Xing, R. H. & Rabbani, S. A. Methylation status of uPA promoter as a molecular mechanism regulating prostate cancer invasion and growth in vitro and in vivo. FASEB J. 17, 1081-1088 (2003). (Pubitemid 36676394)
-
(2003)
FASEB Journal
, vol.17
, Issue.9
, pp. 1081-1088
-
-
Pakneshan, P.1
Xing, R.H.2
Rabbani, S.A.3
-
198
-
-
27944504788
-
Promoter hypomethylation of the LINE-1 retrotransposable elements activates sense/antisense transcription and marks the progression of chronic myeloid leukemia
-
DOI 10.1038/sj.onc.1208866, PII 1208866
-
Roman-Gomez, J., et al. Promoter hypomethylation of the LINE-1 retrotransposable elements activates sense/antisense transcription and marks the progression of chronic myeloid leukemia. Oncogene 24, 7213-7223 (2005). (Pubitemid 41679283)
-
(2005)
Oncogene
, vol.24
, Issue.48
, pp. 7213-7223
-
-
Roman-Gomez, J.1
Jimenez-Velasco, A.2
Agirre, X.3
Cervantes, F.4
Sanchez, J.5
Garate, L.6
Barrios, M.7
Castillejo, J.A.8
Navarro, G.9
Colomer, D.10
Prosper, F.11
Heiniger, A.12
Torres, A.13
-
199
-
-
9944233064
-
Distinctive pattern of LINE-1 methylation level in normal tissues and the association with carcinogenesis
-
DOI 10.1038/sj.onc.1208137
-
Chalitchagorn, K., et al. Distinctive pattern of LINE-1 methylation level in normal tissues and the association with carcinogenesis. Oncogene 23, 8841-8846 (2004). (Pubitemid 39593298)
-
(2004)
Oncogene
, vol.23
, Issue.54
, pp. 8841-8846
-
-
Chalitchagorn, K.1
Shuangshoti, S.2
Hourpai, N.3
Kongruttanachok, N.4
Tangkijvanich, P.5
Thong-ngam, D.6
Voravud, N.7
Sriuranpong, V.8
Mutirangura, A.9
-
200
-
-
0037068353
-
DNA methylation in cancer: Too much, but also too little
-
DOI 10.1038/sj.onc.1205651
-
Ehrlich, M. DNA methylation in cancer: too much, but also too littlE. Oncogene 21, 5400-5413 (2002). (Pubitemid 34983477)
-
(2002)
Oncogene
, vol.21
, Issue.REV. ISS. 3
, pp. 5400-5413
-
-
Ehrlich, M.1
-
201
-
-
0036022068
-
Genomewide DNA hypomethylation is associated with alterations on chromosome 8 in prostate carcinoma
-
DOI 10.1002/gcc.10092
-
Schulz, W.A., et al. Genomewide DNA hypomethylation is associated with alterations on chromosome 8 in prostate carcinoma. Genes Chromosomes Cancer 35, 58-65 (2002). (Pubitemid 34847869)
-
(2002)
Genes Chromosomes and Cancer
, vol.35
, Issue.1
, pp. 58-65
-
-
Schulz, W.A.1
Elo, J.P.2
Florl, A.R.3
Pennanen, S.4
Santourlidis, S.5
Engers, R.6
Buchardt, M.7
Seifert, H.-H.8
Visakorpi, T.9
-
202
-
-
0242584454
-
Chromosomal instability and tumors promoted by DNA hypomethylation
-
DOI 10.1126/science.1083557
-
Eden, A., Gaudet, F., waghmare, A. & Jaenisch, R. Chromosomal instability and tumors promoted by DNA hypomethylatioN. Science 300, 455 (2003). (Pubitemid 36444319)
-
(2003)
Science
, vol.300
, Issue.5618
, pp. 455
-
-
Eden, A.1
Gaudet, F.2
Waghmare, A.3
Jaenisch, R.4
-
203
-
-
0029593458
-
Regional loss of imprinting of the insulin-like growth factor II gene occurs in human prostate tissues
-
Jarrard, D. F., Bussemakers, M. J., Bova, G. S. & Isaacs, W. B. Regional loss of imprinting of the insulin-like growth factor II gene occurs in human prostate tissues. CliN. Cancer Res. 1, 1471-1478 (1995). (Pubitemid 26028082)
-
(1995)
Clinical Cancer Research
, vol.1
, Issue.12
, pp. 1471-1478
-
-
Jarrard, D.F.1
Bussemakers, M.J.G.2
Bova, G.S.3
Isaacs, W.B.4
-
204
-
-
38649123072
-
Conserved Metabolic Regulatory Functions of Sirtuins
-
DOI 10.1016/j.cmet.2007.11.006, PII S1550413107003415
-
Schwer, B. & verdin, E. Conserved metabolic regulatory functions of sirtuins. Cell. Metab. 7, 104-112 (2008). (Pubitemid 351168554)
-
(2008)
Cell Metabolism
, vol.7
, Issue.2
, pp. 104-112
-
-
Schwer, B.1
Verdin, E.2
-
205
-
-
57749170458
-
The many roles of histone deacetylases in development and physiology: Implications for disease and therapy
-
Haberland, M., Montgomery, R. L. & Olson, E. N. The many roles of histone deacetylases in development and physiology: implications for disease and therapy. Nat. ReV. Genet. 10, 32-42 (2009).
-
(2009)
Nat. ReV. Genet.
, vol.10
, pp. 32-42
-
-
Haberland, M.1
Montgomery, R.L.2
Olson, E.N.3
|