Site-specific DNA methylation in the neurofibromatosis (NF1) promoter interferes with binding of CREB and SP1 transcription factors

Oncogene

Volumn 18, Issue 28, 1999, Pages 4108-4119

  Mancini, Debora N ^a,b   Singh, Shiva M ^a,b   Archer, Trevor K ^b   Rodenhiser, David I ^a,b  

^a LONDON HEALTH SCIENCES CENTRE   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

CpG island; CREB; DNA methylation; Neurofibromatosis; Promoter; SP1

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DNA; DNA BINDING PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SP1;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; FEMALE; GEL MOBILITY SHIFT ASSAY; MALE; MOUSE; NEUROFIBROMATOSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; TUMOR SUPPRESSOR GENE;

ANIMALS; BINDING SITES; BINDING, COMPETITIVE; CPG ISLANDS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DNA; DNA METHYLATION; GENE EXPRESSION REGULATION; GENES, NEUROFIBROMATOSIS 1; HUMANS; MICE; ORGAN SPECIFICITY; POLYMERASE CHAIN REACTION; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; SP1 TRANSCRIPTION FACTOR;

ANIMALIA;

EID: 0033566127     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202764     Document Type: Article

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