Preneoplastic prostate lesions: An opportunity for prostate cancer prevention

Annals of the New York Academy of Sciences

Volumn 952, Issue , 2001, Pages 135-144

  Nelson, William G ^a,b   De Marzo, Angelo M ^a   Deweese, Theodore L ^a   Lin, Xiaohui ^a   Brooks, James D ^a   Putzi, Matthew J ^a   Nelson, Chad P ^a   Groopman, John D ^a   Kensler, Thomas W ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b Bunting Blaustein Cancer Research Building ^*  (United States)

Author keywords

Glutathione S transferase (GST); Proliferative inflammatory atrophy; Prostate cancer; Prostatic epithelial lesions

Indexed keywords

ANTIOXIDANT; FAT; GLUTATHIONE TRANSFERASE; OXIDIZING AGENT;

CANCER PREVENTION; CARCINOGENESIS; CELL PROLIFERATION; CONFERENCE PAPER; CPG ISLAND; DIET; DNA DAMAGE; DNA METHYLATION; ENVIRONMENTAL FACTOR; ENZYME ACTIVITY; EPIDEMIC; HUMAN; INFLAMMATORY CELL; OXIDATIVE STRESS; PRECANCER; PROSTATE CANCER; PROSTATE EPITHELIUM; PROTEIN EXPRESSION; UNITED STATES;

EID: 0035684270     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2001.tb02734.x     Document Type: Conference Paper

References (64)

1. The prostate: An increasing medical problem
2. Prostate cancer in the era of prostate-specific antigen
3. Cancer statistics, 1999
4. Global cancer statistics
5. Clinical evidence for and implications of the multistep development of prostate cancer
6. The epidemiology of prostate cancer part II: The risk factors
7. Studies of Japanese migrants. I. Mortality from cancer and other diseases among Japanese in the United States
8. Cancer mortality among the Polish-born in the United States
9. Genitourinary pathology in urban male Blacks of South Africa
10. Decreased incidence of prostate cancer with selenium supplementation: Results of a double-blind cancer prevention trial
11. Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin. A randomized controlled trial
12. Lower prostate cancer risk in men with elevated plasma lycopene levels: Results of a prospective analysis
13. Tomatoes, tomato-based products, lycopene, and cancer: Review of the epidemiologic literature
14. Study of prediagnostic selenium level in toenails and the risk of advanced prostate cancer
15. Intake of carotenoids and retinol in relation to risk of prostate cancer
16. Prostate cancer and supplementation with alpha-tocopherol and beta-carotene: Incidence and mortality in a controlled trial
17. Sexual behaviour, STDs and risks for prostate cancer
18. The causes and prevention of cancer
19. Latent carcinoma of prostate of autopsy in seven areas
20. High grade prostatic intraepithelial neoplasia (HGPIN) and prostatic adenocarcinoma between the ages of 20-69: An autopsy study of 249 cases
21. CG island methylation changes near the GSTP1 gene in prostatic intraepithelial neoplasia
22. CG island methylation changes near the GSTP1 gene in prostatic carcinoma cells detected using the polymerase chain reaction: A new prostate cancer biomarker
23. Cytidine methylation of regulatory sequences near the pi-class glutathione S-transferase gene accompanies human prostatic carcinogenesis
24. Evidence that GSTP1 CpG island hypermethylation may be selected during human prostatic carcinogenesis
25. Cancer-susceptibility genes. Gatekeepers and caretakers
26. Models of DNA structure achieve almost perfect discrimination between normal prostate, benign prostatic hyperplasia (BPH), and adenocarcinoma and have a high potential for predicting BPH and prostate cancer
27. Effect of antioxidants on androgen-induced AP-1 and NF-kappaB DNA-binding activity in prostate carcinoma cells
28. Prooxidant-antioxidant shift induced by androgen treatment of human prostate carcinoma cells
29. Heterocyclic aromatic amine formation in grilled bacon, beef and fish and in grill scrapings
30. Heterocyclic amine content in fastfood meat products
31. Metabolism of 2-acetylaminofluorene and benzo(a)pyrene and activation of food-derived heterocyclic amine mutagens by human cytochromes P-450
32. Induction of intestinal adenocarcinomas by 2-amino-1-methyl-6-phenylimidazo[4,5-β]pyridine in Nagase analbuminemic rats
33. Some perspectives on the nutritional aspects of breast cancer research. Food-derived heterocyclic amines as etiologic agents in human mammary cancer
34. 2-Amino-1-methyl-6-phenylimidazo[4,5-β]pyridine is a potent mutagen in the mouse small intestine
35. Metabolic activation and DNA binding of food mutagens and other environmental carcinogens in human mammary epithelial cells
36. Adduction of the heterocyclic amine food mutagens IQ and PhIP to mitochondrial and nuclear DNA in the liver of Fischer-344 rats
37. Analysis of mutations induced by 2-amino-1-methyl-6-phenylimidazo[4,5-β]pyridine (PhIP) in human lymphoblastoid cells
38. Adduct formation at C-8 of guanine on in vitro reaction of the ultimate form of 2-amino-1-methyl-6-phenylimidazo[4,5-β]pyridine with 2′-deoxyguanosine and its phosphate esters
39. Prostate mutations in rats induced by the suspected human carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-β]pyridine
40. The prostate: A target for carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-β]pyridine (PhIP) derived from cooked foods
41. Protection against 2-hydroxyamino-1-methyl-6-phenylimidazo [4,5-β]pyridine (N-OH-PhIP) cytotoxicity and DNA adduct formation in human prostate by glutathione S-transferase P1
42. Genetic alterations in prostate cancer
43. Proliferative inflammatory atrophy of the prostate: Implications for prostatic carcinogenesis
44. Atrophy and hyperplasia in the prostate proper
45. Normal histology of the prostate
46. Distribution of lactoferrin in the normal and inflamed human prostate: An immunohistochemical study
47. Mitotic activity of prostatic epithelium. A study by means of Colcemid
48. Ki-67 expression in early prostate cancer and associated pathological lesions
49. Morphologic transitions between proliferative inflammatory atrophy and high-grade prostatic intraepithelial neoplasia
50. GSTP1 CpG island DNA hypermethylation in hepatocellular carcinomas
51. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
52. Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
53. Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer
54. DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci
55. Inactivation of glutathione S-transferase P1 gene by promoter hypermethylation in human neoplasia
56. Detailed methylation analysis of the glutathione S-transferase pi (GSTP1) gene in prostate cancer
57. A distinct sequence (ATAAA)n separates methylated and unmethylated domains at the 5′-end of the GSTP1 CpG island
58. Chemoprevention of cancer
59. Inhibition of neoplasia by minor dietary constituents
60. Oltipraz chemoprevention trial in Qidong, People's Republic of China: Modulation of serum aflatoxin albumin adduct biomarkers
61. Oltipraz chemoprevention trial in Qidong, People's Republic of China: Study design and clinical outcomes
62. Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates
63. A major inducer of anticarcinogenic protective enzymes from broccoli: Isolation and elucidation of structure
64. Broccoli sprouts: An exceptionally rich source of inducers of enzymes that protect against chemical carcinogens