메뉴 건너뛰기




Volumn 19, Issue 10, 1999, Pages 6690-6698

Roles of cell division and gene transcription in the methylation of CpG islands

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; PROTEIN P16; TRANSCRIPTION FACTOR;

EID: 0032827113     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.19.10.6690     Document Type: Article
Times cited : (126)

References (54)
  • 1
    • 0025006860 scopus 로고
    • High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines
    • Antequera, F., J. Boyes, and A. Bird. 1990. High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines. Cell 62:503-514.
    • (1990) Cell , vol.62 , pp. 503-514
    • Antequera, F.1    Boyes, J.2    Bird, A.3
  • 3
    • 0031964055 scopus 로고    scopus 로고
    • Inhibition of DNA methylation by 5-aza-2'-deoxycytidine suppresses the growth of human tumor cell lines
    • Bender, C. M., M. M. Pao, and P. A. Jones. 1998. Inhibition of DNA methylation by 5-aza-2'-deoxycytidine suppresses the growth of human tumor cell lines. Cancer Res. 58:95-101.
    • (1998) Cancer Res. , vol.58 , pp. 95-101
    • Bender, C.M.1    Pao, M.M.2    Jones, P.A.3
  • 4
    • 0031892481 scopus 로고    scopus 로고
    • DNA methylation as a target for drug design
    • Bender, C. M., J. M. Zingg, and P. A. Jones. 1998. DNA methylation as a target for drug design. Pharmacol. Res. 15:175-187.
    • (1998) Pharmacol. Res. , vol.15 , pp. 175-187
    • Bender, C.M.1    Zingg, J.M.2    Jones, P.A.3
  • 5
    • 0023472826 scopus 로고
    • CpG islands as gene markers in the vertebrate nucleus
    • Bird, A. P. 1987. CpG islands as gene markers in the vertebrate nucleus. Trends Genet. 3:342-347.
    • (1987) Trends Genet. , vol.3 , pp. 342-347
    • Bird, A.P.1
  • 9
    • 0017409254 scopus 로고
    • Functional striated muscle cells from non-myoblast precursors following 5-azacytidine treatment
    • Constantinides, P. G., P. A. Jones, and W. Gevers. 1977. Functional striated muscle cells from non-myoblast precursors following 5-azacytidine treatment. Nature 267:364-366.
    • (1977) Nature , vol.267 , pp. 364-366
    • Constantinides, P.G.1    Jones, P.A.2    Gevers, W.3
  • 10
    • 0027172684 scopus 로고
    • Parental origin-specific epigenetic modification of the mouse H19 gene
    • Ferguson-Smith, A. C., H. Sasaki, B. M. Cattanach, and M. A. Surani. 1993. Parental origin-specific epigenetic modification of the mouse H19 gene. Nature 362:751-755.
    • (1993) Nature , vol.362 , pp. 751-755
    • Ferguson-Smith, A.C.1    Sasaki, H.2    Cattanach, B.M.3    Surani, M.A.4
  • 12
    • 0023216891 scopus 로고
    • CpG islands in vertebrate genomes
    • Gardiner-Garden, M., and M. Frommer. 1987. CpG islands in vertebrate genomes. J. Mol. Biol. 196:261-282.
    • (1987) J. Mol. Biol. , vol.196 , pp. 261-282
    • Gardiner-Garden, M.1    Frommer, M.2
  • 13
    • 0028875205 scopus 로고
    • Methylation of the 5' CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing
    • Gonzalez-Zulueta, M., C. M. Bender, A. S. Yang, T. Nguyen, R. W. Beart, J. M. Van Tornout, and P. A. Jones. 1995. Methylation of the 5' CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing. Cancer Res. 55:4531-4535.
    • (1995) Cancer Res. , vol.55 , pp. 4531-4535
    • Gonzalez-Zulueta, M.1    Bender, C.M.2    Yang, A.S.3    Nguyen, T.4    Beart, R.W.5    Van Tornout, J.M.6    Jones, P.A.7
  • 15
    • 0030738231 scopus 로고    scopus 로고
    • Rapid quantitation of methylation differences at specific sites using methylation-sensitive single nucleotide primer extension (Ms-SNuPE)
    • Gonzalgo, M. L., and P. A. Jones. 1997. Rapid quantitation of methylation differences at specific sites using methylation-sensitive single nucleotide primer extension (Ms-SNuPE). Nucleic Acids Res. 25:2529-2531.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 2529-2531
    • Gonzalgo, M.L.1    Jones, P.A.2
  • 16
    • 0030868694 scopus 로고    scopus 로고
    • Mapping patterns of CpG island methylation in normal and neoplastic cells implicates both upstream and downstream regions in de novo methylation
    • Graff, J. R., J. G. Herman, S. Myohanen, S. B. Baylin, and P. M. Vertino. 1997. Mapping patterns of CpG island methylation in normal and neoplastic cells implicates both upstream and downstream regions in de novo methylation. J. Biol. Chem. 272:22322-22329.
    • (1997) J. Biol. Chem. , vol.272 , pp. 22322-22329
    • Graff, J.R.1    Herman, J.G.2    Myohanen, S.3    Baylin, S.B.4    Vertino, P.M.5
  • 17
    • 0030046322 scopus 로고    scopus 로고
    • Hypermethylation-associated inactivation indicates a tumor suppressor role for p15iNK4B
    • Herman, J. G., J. Jen, A. Merlo, and S. B. Baylin. 1996. Hypermethylation-associated inactivation indicates a tumor suppressor role for p15INK4B. Cancer Res. 56:722-727.
    • (1996) Cancer Res. , vol.56 , pp. 722-727
    • Herman, J.G.1    Jen, J.2    Merlo, A.3    Baylin, S.B.4
  • 19
    • 0028845142 scopus 로고
    • Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers
    • Herman, J. G., A. Merlo, L. Mao, R. G. Lapidus, J. P. Issa, N. E. Davidson, D. Sidransky, and S. B. Baylin. 1995. Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Res. 55:4525-4530.
    • (1995) Cancer Res. , vol.55 , pp. 4525-4530
    • Herman, J.G.1    Merlo, A.2    Mao, L.3    Lapidus, R.G.4    Issa, J.P.5    Davidson, N.E.6    Sidransky, D.7    Baylin, S.B.8
  • 20
    • 0028106737 scopus 로고
    • Dependence of transcriptional repression on CpG methylation density
    • Hsieh, C.-L. 1994. Dependence of transcriptional repression on CpG methylation density. Mol. Cell. Biol. 14:5487-5494.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 5487-5494
    • Hsieh, C.-L.1
  • 21
    • 0030793717 scopus 로고    scopus 로고
    • Stability of patch methylation and its impact in regions of transcriptional initiation and elongation
    • Hsieh, C.-L. 1997. Stability of patch methylation and its impact in regions of transcriptional initiation and elongation. Mol. Cell. Biol. 17:5897-5904.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 5897-5904
    • Hsieh, C.-L.1
  • 22
    • 0029976873 scopus 로고    scopus 로고
    • Switch from monoallelic to biallelic human IGF2 promoter methylation during aging and carcinogenesis
    • Issa, J. P., P. M. Vertino, C. D. Boehm, I. F. Newsham, and S. B. Baylin. 1996. Switch from monoallelic to biallelic human IGF2 promoter methylation during aging and carcinogenesis. Proc. Natl. Acad. Sci. USA 93:11757-11762.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 11757-11762
    • Issa, J.P.1    Vertino, P.M.2    Boehm, C.D.3    Newsham, I.F.4    Baylin, S.B.5
  • 23
    • 0029898837 scopus 로고    scopus 로고
    • DNA methylation errors and cancer
    • Jones, P. A. 1996. DNA methylation errors and cancer. Cancer Res. 56:2463-2467.
    • (1996) Cancer Res. , vol.56 , pp. 2463-2467
    • Jones, P.A.1
  • 24
    • 0032890965 scopus 로고    scopus 로고
    • The DNA methylation paradox
    • Jones, P. A. 1999. The DNA methylation paradox. Trends Genet. 15:34-37.
    • (1999) Trends Genet. , vol.15 , pp. 34-37
    • Jones, P.A.1
  • 25
    • 0032960181 scopus 로고    scopus 로고
    • Cancer epigenetics comes of age
    • Jones, P. A., and P. W. Laird. 1999. Cancer epigenetics comes of age. Nat. Genet. 21:163-167.
    • (1999) Nat. Genet. , vol.21 , pp. 163-167
    • Jones, P.A.1    Laird, P.W.2
  • 26
    • 0018860957 scopus 로고
    • Cellular differentiation, cytidine analogs and DNA methylation
    • Jones, P. A., and S. M. Taylor. 1980. Cellular differentiation, cytidine analogs and DNA methylation. Cell 20:85-93.
    • (1980) Cell , vol.20 , pp. 85-93
    • Jones, P.A.1    Taylor, S.M.2
  • 27
    • 0019888115 scopus 로고
    • Hemimethylated duplex DNAs prepared from 5-azacytidine-treated cells
    • Jones, P. A., and S. M. Taylor. 1981. Hemimethylated duplex DNAs prepared from 5-azacytidine-treated cells. Nucleic Acids Res. 9:2933-2947.
    • (1981) Nucleic Acids Res. , vol.9 , pp. 2933-2947
    • Jones, P.A.1    Taylor, S.M.2
  • 29
    • 0027361810 scopus 로고
    • Inactive chromatin spreads from a focus of methylation
    • Kass, S. U., J. P. Goddard, and R. L. Adams. 1993. Inactive chromatin spreads from a focus of methylation. Mol. Cell. Biol. 13:7372-7379.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 7372-7379
    • Kass, S.U.1    Goddard, J.P.2    Adams, R.L.3
  • 30
    • 0026742792 scopus 로고
    • CpG islands as gene markers in the human genome
    • Larsen, F., G. Gundersen, R. Lopez, and H. Prydz. 1992. CpG islands as gene markers in the human genome. Genomics 13:1095-1107.
    • (1992) Genomics , vol.13 , pp. 1095-1107
    • Larsen, F.1    Gundersen, G.2    Lopez, R.3    Prydz, H.4
  • 31
    • 0027378582 scopus 로고
    • Role for DNA methylation in genomic imprinting
    • Li, E., C. Beard, and R. Jaenisch. 1993. Role for DNA methylation in genomic imprinting. Nature 366:362-365.
    • (1993) Nature , vol.366 , pp. 362-365
    • Li, E.1    Beard, C.2    Jaenisch, R.3
  • 32
    • 0026708177 scopus 로고
    • Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
    • Li, E., T. H. Bestor, and R. Jaenisch. 1992. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69:915-926.
    • (1992) Cell , vol.69 , pp. 915-926
    • Li, E.1    Bestor, T.H.2    Jaenisch, R.3
  • 34
    • 0022627499 scopus 로고
    • Methylation of the mouse hprt gene differs on the active and inactive X chromosomes
    • Lock, L. F., D. W. Melton, C. T. Caskey, and G. R. Martin. 1986. Methylation of the mouse hprt gene differs on the active and inactive X chromosomes. Mol. Cell. Biol. 6:914-924.
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 914-924
    • Lock, L.F.1    Melton, D.W.2    Caskey, C.T.3    Martin, G.R.4
  • 35
    • 0031830718 scopus 로고    scopus 로고
    • An alternative promoter in the mouse major histocompatibility complex class II I-Aβ gene: Implications for the origin of CpG islands
    • Macleod, D., R. R. Ali, and A. Bird. 1998. An alternative promoter in the mouse major histocompatibility complex class II I-Aβ gene: implications for the origin of CpG islands. Mol. Cell. Biol. 18:4433-4443.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 4433-4443
    • Macleod, D.1    Ali, R.R.2    Bird, A.3
  • 36
    • 0027960055 scopus 로고
    • Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island
    • Macleod, D., J. Charlton, J. Mullins, and A. P. Bird. 1994. Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island. Genes Dev. 8:2282-2292.
    • (1994) Genes Dev. , vol.8 , pp. 2282-2292
    • Macleod, D.1    Charlton, J.2    Mullins, J.3    Bird, A.P.4
  • 37
    • 0028333951 scopus 로고
    • Ubiquitous and tenacious methylation of the CpG site in codon 248 of the p53 gene may explain its frequent appearance as a mutational hot spot in human cancer
    • Magewu, A. N., and P. A. Jones. 1994. Ubiquitous and tenacious methylation of the CpG site in codon 248 of the p53 gene may explain its frequent appearance as a mutational hot spot in human cancer. Mol. Cell. Biol. 14:4225-4232.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 4225-4232
    • Magewu, A.N.1    Jones, P.A.2
  • 39
    • 0029011539 scopus 로고
    • 5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
    • Merlo, A., J. G. Herman, L. Mao, D. J. Lee, E. Gabrielson, P. C. Burger, S. B. Baylin, and D. Sidransky. 1995. 5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Nat. Med. 1:686-692.
    • (1995) Nat. Med. , vol.1 , pp. 686-692
    • Merlo, A.1    Herman, J.G.2    Mao, L.3    Lee, D.J.4    Gabrielson, E.5    Burger, P.C.6    Baylin, S.B.7    Sidransky, D.8
  • 40
    • 0023227949 scopus 로고
    • Differential nuclear protein binding to 5-azacytosine-containing DNA as a potential mechanism for 5-aza-2'-deoxycytidine resistance
    • Michalowsky, L. A., and P. A. Jones. 1987. Differential nuclear protein binding to 5-azacytosine-containing DNA as a potential mechanism for 5-aza-2'-deoxycytidine resistance. Mol. Cell. Biol. 7:3076-3083.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 3076-3083
    • Michalowsky, L.A.1    Jones, P.A.2
  • 41
    • 0019510628 scopus 로고
    • Reactivation of an inactive X human chromosome: Evidence for X inactivation by DNA methylation
    • Mohandas, T., R. S. Sparkes, and L. J. Shapiro. 1981. Reactivation of an inactive X human chromosome: evidence for X inactivation by DNA methylation. Science 211:393-396.
    • (1981) Science , vol.211 , pp. 393-396
    • Mohandas, T.1    Sparkes, R.S.2    Shapiro, L.J.3
  • 42
    • 0032574977 scopus 로고    scopus 로고
    • Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
    • Nan, X., H. H. Ng, C. A. Johnson, C. D. Laherty, B. M. Turner, R. N. Eisenman, and A. Bird. 1998. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature 393:386-389.
    • (1998) Nature , vol.393 , pp. 386-389
    • Nan, X.1    Ng, H.H.2    Johnson, C.A.3    Laherty, C.D.4    Turner, B.M.5    Eisenman, R.N.6    Bird, A.7
  • 43
    • 0031860739 scopus 로고    scopus 로고
    • Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases
    • Okano, M., S. Xie, and E. Li. 1998. Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases. Nat Genet. 19: 219-220.
    • (1998) Nat Genet. , vol.19 , pp. 219-220
    • Okano, M.1    Xie, S.2    Li, E.3
  • 44
    • 0028318783 scopus 로고
    • Methylation of the estrogen receptor gene CpG island marks loss of estrogen receptor expression in human breast cancer cells
    • Ottaviano, Y. L., J. P. Issa, F. F. Parl, H. S. Smith, S. B. Baylin, and N. E. Davidson. 1994. Methylation of the estrogen receptor gene CpG island marks loss of estrogen receptor expression in human breast cancer cells. Cancer Res. 54:2552-2555.
    • (1994) Cancer Res. , vol.54 , pp. 2552-2555
    • Ottaviano, Y.L.1    Issa, J.P.2    Parl, F.F.3    Smith, H.S.4    Baylin, S.B.5    Davidson, N.E.6
  • 45
    • 0342737682 scopus 로고
    • DNA methylation patterns: Formation and biological functions
    • A. Razin, H. Cedar, and A. D. Riggs (ed.). Springer-Verlag Press, New York, N.Y.
    • Razin, A. 1984. DNA methylation patterns: formation and biological functions, p. 127-146. In A. Razin, H. Cedar, and A. D. Riggs (ed.), DNA methylation: biochemistry and biological significance. Springer-Verlag Press, New York, N.Y.
    • (1984) DNA Methylation: Biochemistry and Biological Significance , pp. 127-146
    • Razin, A.1
  • 46
    • 0026603943 scopus 로고
    • X-chromosome inactivation and cell memory
    • Riggs, A. D., and G. P. Pfeifer. 1992. X-chromosome inactivation and cell memory. Trends Genet. 8:169-174.
    • (1992) Trends Genet. , vol.8 , pp. 169-174
    • Riggs, A.D.1    Pfeifer, G.P.2
  • 49
    • 0025880514 scopus 로고
    • Growth regulation of mouse DNA methyltransferase gene expression
    • Szyf, M., V. Bozovic, and G. Tanigawa. 1991. Growth regulation of mouse DNA methyltransferase gene expression. J. Biol. Chem. 266:10027-10030.
    • (1991) J. Biol. Chem. , vol.266 , pp. 10027-10030
    • Szyf, M.1    Bozovic, V.2    Tanigawa, G.3
  • 50
    • 0027535235 scopus 로고
    • Effects of DNA methylation on DNA-binding proteins and gene expression
    • Tate, P. H., and A. P. Bird. 1993. Effects of DNA methylation on DNA-binding proteins and gene expression. Curr. Opin. Genet. Dev. 3:226-231.
    • (1993) Curr. Opin. Genet. Dev. , vol.3 , pp. 226-231
    • Tate, P.H.1    Bird, A.P.2
  • 51
    • 0020308438 scopus 로고
    • Mechanism of action of eukaryotic DNA methyltransferase. Use of 5-azacytosine-containing DNA
    • Taylor, S. M., and P. A. Jones. 1982. Mechanism of action of eukaryotic DNA methyltransferase. Use of 5-azacytosine-containing DNA. J. Mol. Biol. 162:679-692.
    • (1982) J. Mol. Biol. , vol.162 , pp. 679-692
    • Taylor, S.M.1    Jones, P.A.2
  • 53
    • 0027496294 scopus 로고
    • Imprinting of human H19: Allele-specific CpG methylation, loss of the active allele in Wilms tumor, and potential for somatic allele switching
    • Zhang, Y., T. Shields, T. Crenshaw, Y. Hao, T. Moulton, and B. Tycko. 1993. Imprinting of human H19: allele-specific CpG methylation, loss of the active allele in Wilms tumor, and potential for somatic allele switching. Am. J. Hum. Genet. 53:113-124.
    • (1993) Am. J. Hum. Genet. , vol.53 , pp. 113-124
    • Zhang, Y.1    Shields, T.2    Crenshaw, T.3    Hao, Y.4    Moulton, T.5    Tycko, B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.