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Volumn 66, Issue 18, 2006, Pages 9202-9210

Alteration of the methylation status of tumor-promoting genes decreases prostate cancer cell invasiveness and tumorigenesis in vitro and in vivo

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; BISULFITE; DRUG VEHICLE; GELATINASE A; GENOMIC DNA; GLUTATHIONE TRANSFERASE P1; OLIGONUCLEOTIDE; PLASMINOGEN ACTIVATOR; S ADENOSYLMETHIONINE; VASCULOTROPIN;

EID: 33749483782     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-06-1954     Document Type: Article
Times cited : (135)

References (44)
  • 2
    • 33646060452 scopus 로고    scopus 로고
    • Androgen-deprivation therapy as primary treatment for localized prostate cancer: Data from Cancer of the Prostate Strategic Urologic Research Endeavor (CaPSURE)
    • Kawakami J, Cowan JE, Elkin EP, et al. Androgen-deprivation therapy as primary treatment for localized prostate cancer: data from Cancer of the Prostate Strategic Urologic Research Endeavor (CaPSURE). Cancer 2006;106:1708-14.
    • (2006) Cancer , vol.106 , pp. 1708-1714
    • Kawakami, J.1    Cowan, J.E.2    Elkin, E.P.3
  • 3
    • 21344470453 scopus 로고    scopus 로고
    • Management of clinically localized prostate cancer by radical prostatectomy followed by watchful waiting
    • Kirby R. Management of clinically localized prostate cancer by radical prostatectomy followed by watchful waiting. Nat Clin Pract Urol 2005;2:298-303.
    • (2005) Nat Clin Pract Urol , vol.2 , pp. 298-303
    • Kirby, R.1
  • 5
    • 0036219874 scopus 로고    scopus 로고
    • Mechanisms involved in the progression of androgen-independent prostate cancers: It is not only the cancer cell's fault
    • Arnold JT, Isaacs JT. Mechanisms involved in the progression of androgen-independent prostate cancers: it is not only the cancer cell's fault. Endocr Relat Cancer 2002;9:61-73.
    • (2002) Endocr Relat Cancer , vol.9 , pp. 61-73
    • Arnold, J.T.1    Isaacs, J.T.2
  • 6
    • 33645830579 scopus 로고    scopus 로고
    • Mechanisms and treatment for bone metastases
    • Clines GA, Guise TA. Mechanisms and treatment for bone metastases. Clin Adv Hematol Oncol 2004;2:295-301.
    • (2004) Clin Adv Hematol Oncol , vol.2 , pp. 295-301
    • Clines, G.A.1    Guise, T.A.2
  • 7
    • 33644620899 scopus 로고    scopus 로고
    • Understanding bone metastases: The key to the effective treatment of prostate cancer
    • Fidler IJ. Understanding bone metastases: the key to the effective treatment of prostate cancer. Clin Adv Hematol Oncol 2003;1:278-9.
    • (2003) Clin Adv Hematol Oncol , vol.1 , pp. 278-279
    • Fidler, I.J.1
  • 9
    • 25444485785 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor C (VEGF-C) and VEGF receptor-3 in human prostate cancer is associated with regional lymph node metastasis
    • Jennbacken K, Vallbo C, Wang W, Damber JE. Expression of vascular endothelial growth factor C (VEGF-C) and VEGF receptor-3 in human prostate cancer is associated with regional lymph node metastasis. Prostate 2005;65:110-6.
    • (2005) Prostate , vol.65 , pp. 110-116
    • Jennbacken, K.1    Vallbo, C.2    Wang, W.3    Damber, J.E.4
  • 10
    • 29844456021 scopus 로고    scopus 로고
    • Growth factors involved in prostate carcinogenesis
    • Kambhampati S, Ray G, Sengupta K, et al. Growth factors involved in prostate carcinogenesis. Front Biosci 2005;10:1355-67.
    • (2005) Front Biosci , vol.10 , pp. 1355-1367
    • Kambhampati, S.1    Ray, G.2    Sengupta, K.3
  • 11
    • 0141837010 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinases (MMP-2 and -9) and their inhibitors (TIMP-1 and -2) in prostate cancer tissue
    • Brehmer B, Biesterfeld S, Jakse G. Expression of matrix metalloproteinases (MMP-2 and -9) and their inhibitors (TIMP-1 and -2) in prostate cancer tissue. Prostate Cancer Prostatic Dis 2003;6:217-22.
    • (2003) Prostate Cancer Prostatic Dis , vol.6 , pp. 217-222
    • Brehmer, B.1    Biesterfeld, S.2    Jakse, G.3
  • 12
    • 0034472617 scopus 로고    scopus 로고
    • Matrix metalloproteinases in tumor invasion and metastasis
    • Stamenkovic I. Matrix metalloproteinases in tumor invasion and metastasis. Semin Cancer Biol 2000;10:415-33.
    • (2000) Semin Cancer Biol , vol.10 , pp. 415-433
    • Stamenkovic, I.1
  • 13
    • 16644374800 scopus 로고    scopus 로고
    • Type IV collagenase (matrix metalloproteinase-2 and -9) in prostate cancer
    • Zhang L, Shi J, Feng J, et al. Type IV collagenase (matrix metalloproteinase-2 and -9) in prostate cancer. Prostate Cancer Prostatic Dis 2004;7:327-32.
    • (2004) Prostate Cancer Prostatic Dis , vol.7 , pp. 327-332
    • Zhang, L.1    Shi, J.2    Feng, J.3
  • 14
    • 0031955355 scopus 로고    scopus 로고
    • Metalloproteases and urokinase in angiogenesis and tumor progression
    • Rabbani SA. Metalloproteases and urokinase in angiogenesis and tumor progression. In Vivo 1998;12:135-42.
    • (1998) In Vivo , vol.12 , pp. 135-142
    • Rabbani, S.A.1
  • 15
    • 0034996039 scopus 로고    scopus 로고
    • The role of the plasminogen activation system in angiogenesis and metastasis
    • Rabbani SA, Mazar AP. The role of the plasminogen activation system in angiogenesis and metastasis. Surg Oncol Clin N Am 2001;10:393-415.
    • (2001) Surg Oncol Clin N Am , vol.10 , pp. 393-415
    • Rabbani, S.A.1    Mazar, A.P.2
  • 16
    • 0031892133 scopus 로고    scopus 로고
    • Role of urokinase (uPA) and its receptor (uPAR) in invasion and metastasis of hormone-dependent malignancies
    • Rabbani SA, Xing RH. Role of urokinase (uPA) and its receptor (uPAR) in invasion and metastasis of hormone-dependent malignancies. Int J Oncol 1998;12:911-20.
    • (1998) Int J Oncol , vol.12 , pp. 911-920
    • Rabbani, S.A.1    Xing, R.H.2
  • 17
    • 13144251125 scopus 로고    scopus 로고
    • DNA methylation and cancer therapy: New developments and expectations
    • Esteller M. DNA methylation and cancer therapy: new developments and expectations. Curr Opin Oncol 2005;17:55-60.
    • (2005) Curr Opin Oncol , vol.17 , pp. 55-60
    • Esteller, M.1
  • 18
    • 0036276433 scopus 로고    scopus 로고
    • Epigenetic cancer therapies: DNA methyltransferase inhibitors
    • Strathdee G, Brown R. Epigenetic cancer therapies: DNA methyltransferase inhibitors. Expert Opin Investig Drugs 2002;11:747-54.
    • (2002) Expert Opin Investig Drugs , vol.11 , pp. 747-754
    • Strathdee, G.1    Brown, R.2
  • 19
    • 0348217891 scopus 로고    scopus 로고
    • Epigenetic transitions: Towards therapeutic targets
    • Kalebic T. Epigenetic transitions: towards therapeutic targets. Expert Opin Ther Targets 2003;7:693-9.
    • (2003) Expert Opin Ther Targets , vol.7 , pp. 693-699
    • Kalebic, T.1
  • 20
    • 0036216505 scopus 로고    scopus 로고
    • Epigenomics and epigenetic therapy of cancer
    • Brown R, Strathdee G. Epigenomics and epigenetic therapy of cancer. Trends Mol Med 2002;8:S43-8.
    • (2002) Trends Mol Med , vol.8
    • Brown, R.1    Strathdee, G.2
  • 21
    • 0347622294 scopus 로고    scopus 로고
    • Targeting DNA methylation in cancer
    • Szyf M. Targeting DNA methylation in cancer. Ageing Res Rev 2003;2:299-328.
    • (2003) Ageing Res Rev , vol.2 , pp. 299-328
    • Szyf, M.1
  • 22
    • 0019318994 scopus 로고
    • DNA methylation and gene function
    • Razin A, Riggs AD. DNA methylation and gene function. Science 1980;210:604-10.
    • (1980) Science , vol.210 , pp. 604-610
    • Razin, A.1    Riggs, A.D.2
  • 23
    • 0034744639 scopus 로고    scopus 로고
    • Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer
    • Baylin SB, Esteller M, Rountree MB, et al. Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer. Hum Mol Genet 2001;10:687-92.
    • (2001) Hum Mol Genet , vol.10 , pp. 687-692
    • Baylin, S.B.1    Esteller, M.2    Rountree, M.B.3
  • 24
    • 0037068353 scopus 로고    scopus 로고
    • DNA methylation in cancer: Too much, but also too little
    • Ehrlich M. DNA methylation in cancer: too much, but also too little. Oncogene 2002;21:5400-13.
    • (2002) Oncogene , vol.21 , pp. 5400-5413
    • Ehrlich, M.1
  • 25
    • 0037709969 scopus 로고    scopus 로고
    • Methylation status of uPA promoter as a molecular mechanism regulating prostate cancer invasion and growth in vitro and in vivo
    • Pakneshan P, Xing RH, Rabbani SA. Methylation status of uPA promoter as a molecular mechanism regulating prostate cancer invasion and growth in vitro and in vivo. FASEB J 2003;17:1081-8.
    • (2003) FASEB J , vol.17 , pp. 1081-1088
    • Pakneshan, P.1    Xing, R.H.2    Rabbani, S.A.3
  • 26
    • 0038080948 scopus 로고    scopus 로고
    • The methyl donor 5-adenosylmethionine inhibits active demethylation of DNA: A candidate novel mechanism for the pharmacological effects of S-adenosylmethionine
    • Detich N, Hamm S, Just G, Knox JD, Szyf M. The methyl donor 5-adenosylmethionine inhibits active demethylation of DNA: a candidate novel mechanism for the pharmacological effects of S-adenosylmethionine. J Biol Chem 2003;278:20812-20.
    • (2003) J Biol Chem , vol.278 , pp. 20812-20820
    • Detich, N.1    Hamm, S.2    Just, G.3    Knox, J.D.4    Szyf, M.5
  • 27
    • 0029926820 scopus 로고    scopus 로고
    • S-adenosylmethionine and methylation
    • Chiang PK, Gordon RK, Tal J, et al. S-adenosylmethionine and methylation. FASEB J 1996;10:471-80.
    • (1996) FASEB J , vol.10 , pp. 471-480
    • Chiang, P.K.1    Gordon, R.K.2    Tal, J.3
  • 28
    • 3843125363 scopus 로고    scopus 로고
    • Reversal of the hypomethylation status of urokinase (uPA) promoter blocks breast cancer growth and metastasis
    • Pakneshan P, Szyf M, Farias-Eisner R, Rabbani SA. Reversal of the hypomethylation status of urokinase (uPA) promoter blocks breast cancer growth and metastasis. J Biol Chem 2004;279:31735-44.
    • (2004) J Biol Chem , vol.279 , pp. 31735-31744
    • Pakneshan, P.1    Szyf, M.2    Farias-Eisner, R.3    Rabbani, S.A.4
  • 29
    • 0036186811 scopus 로고    scopus 로고
    • DNA methyltransferase and demethylase in human prostate cancer
    • Patra SK, Patra A, Zhao H, Dahiya R. DNA methyltransferase and demethylase in human prostate cancer. Mol Carcinog 2002;33:163-71.
    • (2002) Mol Carcinog , vol.33 , pp. 163-171
    • Patra, S.K.1    Patra, A.2    Zhao, H.3    Dahiya, R.4
  • 30
    • 13644255586 scopus 로고    scopus 로고
    • Antisense MBD2 gene therapy inhibits tumorigenesis
    • Slack A, Bovenzi V, Bigey P, et al. Antisense MBD2 gene therapy inhibits tumorigenesis. J Gene Med 2002;4:381-9.
    • (2002) J Gene Med , vol.4 , pp. 381-389
    • Slack, A.1    Bovenzi, V.2    Bigey, P.3
  • 31
    • 0037603586 scopus 로고    scopus 로고
    • Deficiency of Mbd2 suppresses intestinal tumorigenesis
    • Sansom OJ, Berger J, Bishop SM, et al. Deficiency of Mbd2 suppresses intestinal tumorigenesis. Nat Genet 2003;34:145-7.
    • (2003) Nat Genet , vol.34 , pp. 145-147
    • Sansom, O.J.1    Berger, J.2    Bishop, S.M.3
  • 32
    • 28844490115 scopus 로고    scopus 로고
    • Role of MBD2 in gene regulation and tumorigenesis
    • Berger J, Bird A. Role of MBD2 in gene regulation and tumorigenesis. Biochem Soc Trans 2005;33:1537-40.
    • (2005) Biochem Soc Trans , vol.33 , pp. 1537-1540
    • Berger, J.1    Bird, A.2
  • 33
    • 3843113658 scopus 로고    scopus 로고
    • Methylated DNA-binding protein 2 antisense inhibitors suppress tumourigenesis of human cancer cell lines in vitro and in vivo
    • Campbell PM, Bovenzi V, Szyf M. Methylated DNA-binding protein 2 antisense inhibitors suppress tumourigenesis of human cancer cell lines in vitro and in vivo. Carcinogenesis 2004;25:499-507.
    • (2004) Carcinogenesis , vol.25 , pp. 499-507
    • Campbell, P.M.1    Bovenzi, V.2    Szyf, M.3
  • 35
    • 4444326415 scopus 로고    scopus 로고
    • Up-regulation of Wnt-1 and β-catenin production in patients with advanced metastatic prostate carcinoma: Potential pathogenetic and prognostic implications
    • Chen G, Shukeir N, Potti A, et al. Up-regulation of Wnt-1 and β-catenin production in patients with advanced metastatic prostate carcinoma: potential pathogenetic and prognostic implications. Cancer 2004;101:1345-56.
    • (2004) Cancer , vol.101 , pp. 1345-1356
    • Chen, G.1    Shukeir, N.2    Potti, A.3
  • 36
    • 0035320566 scopus 로고    scopus 로고
    • The role of DNA methyltransferase 1 in growth control
    • Szyf M. The role of DNA methyltransferase 1 in growth control. Front Biosci 2001;6:D599-609.
    • (2001) Front Biosci , vol.6
    • Szyf, M.1
  • 37
    • 0028964323 scopus 로고
    • Expression of antisense to DNA methyltransferase mRNA induces DNA demethylation and inhibits tumorigenesis
    • MacLeod AR, Szyf M. Expression of antisense to DNA methyltransferase mRNA induces DNA demethylation and inhibits tumorigenesis. J Biol Chem 1995;270:8037-43.
    • (1995) J Biol Chem , vol.270 , pp. 8037-8043
    • MacLeod, A.R.1    Szyf, M.2
  • 38
    • 0031025621 scopus 로고    scopus 로고
    • Inhibition of tumorigenesis by a cytosine-DNA, methyltransferase, antisense oligodeoxynucleotide
    • Ramchandani S, MacLeod AR, Pinard M, von Hofe E, Szyf M. Inhibition of tumorigenesis by a cytosine-DNA, methyltransferase, antisense oligodeoxynucleotide. Proc Natl Acad Sci U S A 1997;94:684-9.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 684-689
    • Ramchandani, S.1    MacLeod, A.R.2    Pinard, M.3    Von Hofe, E.4    Szyf, M.5
  • 39
    • 31544458225 scopus 로고    scopus 로고
    • Inhibition of DNA methyltransferase activity prevents tumorigenesis in a mouse model of prostate cancer
    • McCabe MT, Low JA, Daignault S, et al. Inhibition of DNA methyltransferase activity prevents tumorigenesis in a mouse model of prostate cancer. Cancer Res 2006;66:385-92.
    • (2006) Cancer Res , vol.66 , pp. 385-392
    • McCabe, M.T.1    Low, J.A.2    Daignault, S.3
  • 40
    • 0037453906 scopus 로고    scopus 로고
    • Effects of 5-aza-2′-deoxycytidine on matrix metalloproteinase expression and pancreatic cancer cell invasiveness
    • Sato N, Maehara N, Su GH, Goggins M. Effects of 5-aza-2′- deoxycytidine on matrix metalloproteinase expression and pancreatic cancer cell invasiveness. J Natl Cancer Inst 2003;95:327-30.
    • (2003) J Natl Cancer Inst , vol.95 , pp. 327-330
    • Sato, N.1    Maehara, N.2    Su, G.H.3    Goggins, M.4
  • 41
    • 0033395272 scopus 로고    scopus 로고
    • Genomic instability: First step to carcinogenesis
    • Schmutte C, Fishel R. Genomic instability: first step to carcinogenesis. Anticancer Res 1999;19:4665-96.
    • (1999) Anticancer Res , vol.19 , pp. 4665-4696
    • Schmutte, C.1    Fishel, R.2
  • 42
    • 0032871399 scopus 로고    scopus 로고
    • MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex
    • Ng HH, Zhang Y, Hendrich B, et al. MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex. Nat Genet 1999;23:58-61.
    • (1999) Nat Genet , vol.23 , pp. 58-61
    • Ng, H.H.1    Zhang, Y.2    Hendrich, B.3
  • 43
    • 0033580326 scopus 로고    scopus 로고
    • A mammalian protein with specific demethylase activity for mCpG DNA
    • Bhattacharya SK, Ramchandani S, Cervoni N, Szyf M. A mammalian protein with specific demethylase activity for mCpG DNA. Nature 1999;397:579-83.
    • (1999) Nature , vol.397 , pp. 579-583
    • Bhattacharya, S.K.1    Ramchandani, S.2    Cervoni, N.3    Szyf, M.4
  • 44
    • 0037183968 scopus 로고    scopus 로고
    • Promoter-specific activation and demethylation by MBD2/demethylase
    • Detich N, Theberge J, Szyf M. Promoter-specific activation and demethylation by MBD2/demethylase. J Biol Chem 2002;277:35791-4.
    • (2002) J Biol Chem , vol.277 , pp. 35791-35794
    • Detich, N.1    Theberge, J.2    Szyf, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.