-
1
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D., Weinberg R.A. The hallmarks of cancer. Cell 2000, 100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
2
-
-
4043181214
-
Cancer genes and the pathways they control
-
Vogelstein B., Kinzler K.W. Cancer genes and the pathways they control. Nat Med 2004, 10:789-799.
-
(2004)
Nat Med
, vol.10
, pp. 789-799
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
4
-
-
0037178722
-
Maintenance of genome stability in Saccharomyces cerevisiae
-
Kolodner R.D., Putnam C.D., Myung K. Maintenance of genome stability in Saccharomyces cerevisiae. Science 2002, 297:552-557.
-
(2002)
Science
, vol.297
, pp. 552-557
-
-
Kolodner, R.D.1
Putnam, C.D.2
Myung, K.3
-
5
-
-
0017167185
-
The clonal evolution of tumor cell populations
-
Nowell P.C. The clonal evolution of tumor cell populations. Science 1976, 194:23-28.
-
(1976)
Science
, vol.194
, pp. 23-28
-
-
Nowell, P.C.1
-
6
-
-
0016176530
-
Errors in DNA replication as a basis of malignant changes
-
Loeb L.A., Springgate C.F., Battula N. Errors in DNA replication as a basis of malignant changes. Cancer Res 1974, 34:2311-2321.
-
(1974)
Cancer Res
, vol.34
, pp. 2311-2321
-
-
Loeb, L.A.1
Springgate, C.F.2
Battula, N.3
-
7
-
-
45549102966
-
Cancers exhibit a mutator phenotype: clinical implications
-
Loeb L.A., Bielas J.H., Beckman R.A. Cancers exhibit a mutator phenotype: clinical implications. Cancer Res 2008, 68:3551-3557.
-
(2008)
Cancer Res
, vol.68
, pp. 3551-3557
-
-
Loeb, L.A.1
Bielas, J.H.2
Beckman, R.A.3
-
8
-
-
45549085055
-
Genetic instability is not a requirement for tumor development
-
Bodmer W. Genetic instability is not a requirement for tumor development. Cancer Res 2008, 68:3558-3560.
-
(2008)
Cancer Res
, vol.68
, pp. 3558-3560
-
-
Bodmer, W.1
-
9
-
-
0028172057
-
Cancers beget mutations versus mutations beget cancers
-
Prehn R.T. Cancers beget mutations versus mutations beget cancers. Cancer Res 1994, 54:5296-5300.
-
(1994)
Cancer Res
, vol.54
, pp. 5296-5300
-
-
Prehn, R.T.1
-
11
-
-
0035198088
-
Cancer: the evolved consequence of a destabilized genome
-
Anderson G.R., Stoler D.L., Brenner B.M. Cancer: the evolved consequence of a destabilized genome. Bioessays 2001, 23:1037-1046.
-
(2001)
Bioessays
, vol.23
, pp. 1037-1046
-
-
Anderson, G.R.1
Stoler, D.L.2
Brenner, B.M.3
-
12
-
-
36949025507
-
Genetic progression and the waiting time to cancer
-
Beerenwinkel N., Antal T., Dingli D., Traulsen A., Kinzler K.W., Velculescu V.E., et al. Genetic progression and the waiting time to cancer. PLoS Comput Biol 2007, 3:e225.
-
(2007)
PLoS Comput Biol
, vol.3
-
-
Beerenwinkel, N.1
Antal, T.2
Dingli, D.3
Traulsen, A.4
Kinzler, K.W.5
Velculescu, V.E.6
-
15
-
-
0037178710
-
-
Special Issue on Genome Instability
-
Special Issue on Genome Instability Science 2002, 297:543-569.
-
(2002)
Science
, vol.297
, pp. 543-569
-
-
-
16
-
-
77649144557
-
-
Special Issue on Genome Instability
-
Special Issue on Genome Instability Nat Rev Mol Cell Biol 2010, 11:165-228.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 165-228
-
-
-
17
-
-
33947581390
-
The impact of translocations and gene fusions on cancer causation
-
Mitelman F., Johansson B., Mertens F. The impact of translocations and gene fusions on cancer causation. Nat Rev Cancer 2007, 7:233-245.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 233-245
-
-
Mitelman, F.1
Johansson, B.2
Mertens, F.3
-
19
-
-
0024357990
-
Differences in the rate of gene amplification in nontumorigenic and tumorigenic cell lines as measured by Luria-Delbruk fluctuation analysis
-
Tlsty T.D., Margolin B.H., Lum K. Differences in the rate of gene amplification in nontumorigenic and tumorigenic cell lines as measured by Luria-Delbruk fluctuation analysis. Proc Natl Acad Sci USA 1989, 86:9441-9445.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 9441-9445
-
-
Tlsty, T.D.1
Margolin, B.H.2
Lum, K.3
-
20
-
-
0029827630
-
Loss of heterozygosity and base substitution at the APRT locus in mismatch repair-proficient and -deficient colorectal carcinoma cell lines
-
Phear G., Bhattacharyya N.P., Meuth M. Loss of heterozygosity and base substitution at the APRT locus in mismatch repair-proficient and -deficient colorectal carcinoma cell lines. Mol Cell Biol 1996, 16:6516-6523.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 6516-6523
-
-
Phear, G.1
Bhattacharyya, N.P.2
Meuth, M.3
-
21
-
-
0031004175
-
Genetic instability in colorectal cancers
-
Lengauer C., Kinzler K.W., Vogelstein B. Genetic instability in colorectal cancers. Nature 1997, 386:623-627.
-
(1997)
Nature
, vol.386
, pp. 623-627
-
-
Lengauer, C.1
Kinzler, K.W.2
Vogelstein, B.3
-
22
-
-
0035902108
-
Genome maintenance mechanisms for preventing cancer
-
Hoeijmakers J.H. Genome maintenance mechanisms for preventing cancer. Nature 2001, 411:366-374.
-
(2001)
Nature
, vol.411
, pp. 366-374
-
-
Hoeijmakers, J.H.1
-
23
-
-
0036220630
-
Caretaker tumour suppressor genes that defend genome integrity
-
Levitt N.C., Hickson I.D. Caretaker tumour suppressor genes that defend genome integrity. Trends Mol Med 2002, 8:179-186.
-
(2002)
Trends Mol Med
, vol.8
, pp. 179-186
-
-
Levitt, N.C.1
Hickson, I.D.2
-
24
-
-
70350065725
-
Disorders of nucleotide excision repair: the genetic and molecular basis of heterogeneity
-
Cleaver J.E., Lam E.T., Revet I. Disorders of nucleotide excision repair: the genetic and molecular basis of heterogeneity. Nat Rev Genet 2009, 10:756-768.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 756-768
-
-
Cleaver, J.E.1
Lam, E.T.2
Revet, I.3
-
25
-
-
33845311843
-
Human cancers express a mutator phenotype
-
Bielas J.H., Loeb K.R., Rubin B.P., True L.D., Loeb L.A. Human cancers express a mutator phenotype. Proc Natl Acad Sci USA 2006, 103:18238-18242.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 18238-18242
-
-
Bielas, J.H.1
Loeb, K.R.2
Rubin, B.P.3
True, L.D.4
Loeb, L.A.5
-
26
-
-
33845309647
-
Random mutations, selected mutations: a PIN opens the door to new genetic landscapes
-
Klein C.A. Random mutations, selected mutations: a PIN opens the door to new genetic landscapes. Proc Natl Acad Sci USA 2006, 103:18033-18034.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 18033-18034
-
-
Klein, C.A.1
-
28
-
-
4944240144
-
Genetic predisposition to colorectal cancer
-
de la Chapelle A. Genetic predisposition to colorectal cancer. Nat Rev Cancer 2004, 4:769-780.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 769-780
-
-
de la Chapelle, A.1
-
29
-
-
53149152985
-
Lynch syndrome and related familial colorectal cancers
-
[discussion 23-31]
-
Abdel-Rahman W.M., Peltomaki P. Lynch syndrome and related familial colorectal cancers. Crit Rev Oncog 2008, 14:1-22. [discussion 23-31].
-
(2008)
Crit Rev Oncog
, vol.14
, pp. 1-22
-
-
Abdel-Rahman, W.M.1
Peltomaki, P.2
-
30
-
-
67650924286
-
Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramifications
-
Lynch H.T., Lynch P.M., Lanspa S.J., Snyder C.L., Lynch J.F., Boland C.R. Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramifications. Clin Genet 2009, 76:1-18.
-
(2009)
Clin Genet
, vol.76
, pp. 1-18
-
-
Lynch, H.T.1
Lynch, P.M.2
Lanspa, S.J.3
Snyder, C.L.4
Lynch, J.F.5
Boland, C.R.6
-
31
-
-
77449130761
-
Microsatellite instability in colorectal cancer
-
Boland C.R., Goel A. Microsatellite instability in colorectal cancer. Gastroenterology 2010, 138:2073-2087.
-
(2010)
Gastroenterology
, vol.138
, pp. 2073-2087
-
-
Boland, C.R.1
Goel, A.2
-
32
-
-
0027742295
-
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
-
Fishel R., Lescoe M.K., Rao M.R., Copeland N.G., Jenkins N.A., Garber J., et al. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell 1993, 75:1027-1038.
-
(1993)
Cell
, vol.75
, pp. 1027-1038
-
-
Fishel, R.1
Lescoe, M.K.2
Rao, M.R.3
Copeland, N.G.4
Jenkins, N.A.5
Garber, J.6
-
33
-
-
0027145633
-
Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer
-
Leach F.S., Nicolaides N.C., Papadopoulos N., Liu B., Jen J., Parsons R., et al. Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell 1993, 75:1215-1225.
-
(1993)
Cell
, vol.75
, pp. 1215-1225
-
-
Leach, F.S.1
Nicolaides, N.C.2
Papadopoulos, N.3
Liu, B.4
Jen, J.5
Parsons, R.6
-
34
-
-
0028221943
-
Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer
-
Bronner C.E., Baker S.M., Morrison P.T., Warren G., Smith L.G., Lescoe M.K., et al. Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer. Nature 1994, 368:258-261.
-
(1994)
Nature
, vol.368
, pp. 258-261
-
-
Bronner, C.E.1
Baker, S.M.2
Morrison, P.T.3
Warren, G.4
Smith, L.G.5
Lescoe, M.K.6
-
35
-
-
0028350601
-
Mutation of a mutL homolog in hereditary colon cancer
-
Papadopoulos N., Nicolaides N.C., Wei Y.-F., Ruben S.M., Carter K.C., Rosen C.A., et al. Mutation of a mutL homolog in hereditary colon cancer. Science 1994, 263:1625-1629.
-
(1994)
Science
, vol.263
, pp. 1625-1629
-
-
Papadopoulos, N.1
Nicolaides, N.C.2
Wei, Y.-F.3
Ruben, S.M.4
Carter, K.C.5
Rosen, C.A.6
-
36
-
-
4544310802
-
Mutations associated with HNPCC predisposition-update of ICG-HNPCC/INSiGHT mutation database
-
Peltomaki P., Vasen H. Mutations associated with HNPCC predisposition-update of ICG-HNPCC/INSiGHT mutation database. Dis Markers 2004, 20:269-276.
-
(2004)
Dis Markers
, vol.20
, pp. 269-276
-
-
Peltomaki, P.1
Vasen, H.2
-
37
-
-
77951645053
-
Hereditary and familial colon cancer
-
Jasperson K.W., Tuohy T.M., Neklason D.W., Burt R.W. Hereditary and familial colon cancer. Gastroenterology 2010, 138:2044-2058.
-
(2010)
Gastroenterology
, vol.138
, pp. 2044-2058
-
-
Jasperson, K.W.1
Tuohy, T.M.2
Neklason, D.W.3
Burt, R.W.4
-
38
-
-
41849101441
-
Carcinogenesis and microsatellite instability: the interrelationship between genetics and epigenetics
-
Imai K., Yamamoto H. Carcinogenesis and microsatellite instability: the interrelationship between genetics and epigenetics. Carcinogenesis 2008, 29:673-680.
-
(2008)
Carcinogenesis
, vol.29
, pp. 673-680
-
-
Imai, K.1
Yamamoto, H.2
-
39
-
-
0032525214
-
Microsatellite instability in human solid tumors
-
Arzimanoglou I.I., Gilbert F., Barber H.R. Microsatellite instability in human solid tumors. Cancer 1998, 82:1808-1820.
-
(1998)
Cancer
, vol.82
, pp. 1808-1820
-
-
Arzimanoglou, I.I.1
Gilbert, F.2
Barber, H.R.3
-
41
-
-
0028224645
-
Mutator phenotypes in human colorectal carcinoma cell lines
-
Bhattacharyya N.P., Skandalis A., Ganesh A., Groden J., Meuth M. Mutator phenotypes in human colorectal carcinoma cell lines. Proc Natl Acad Sci USA 1994, 91:6319-6323.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 6319-6323
-
-
Bhattacharyya, N.P.1
Skandalis, A.2
Ganesh, A.3
Groden, J.4
Meuth, M.5
-
42
-
-
0028887597
-
Increased mutation rate at the hprt locus accompanies microsatellite instability in colon cancer
-
Eshleman J.R., Lang E.Z., Bowerfind G.K., Parsons R., Vogelstein B., Willson J.K., et al. Increased mutation rate at the hprt locus accompanies microsatellite instability in colon cancer. Oncogene 1995, 10:33-37.
-
(1995)
Oncogene
, vol.10
, pp. 33-37
-
-
Eshleman, J.R.1
Lang, E.Z.2
Bowerfind, G.K.3
Parsons, R.4
Vogelstein, B.5
Willson, J.K.6
-
43
-
-
0031894343
-
Functional overlap in mismatch repair by human MSH3 and MSH6
-
Umar A., Risinger J.I., Glaab W.E., Tindall K.R., Barrett J.C., Kunkel T.A. Functional overlap in mismatch repair by human MSH3 and MSH6. Genetics 1998, 148:1637-1646.
-
(1998)
Genetics
, vol.148
, pp. 1637-1646
-
-
Umar, A.1
Risinger, J.I.2
Glaab, W.E.3
Tindall, K.R.4
Barrett, J.C.5
Kunkel, T.A.6
-
44
-
-
0036569940
-
Mutations at coding repeat sequences in mismatch repair-deficient human cancers: toward a new concept of target genes for instability
-
Duval A., Hamelin R. Mutations at coding repeat sequences in mismatch repair-deficient human cancers: toward a new concept of target genes for instability. Cancer Res 2002, 62:2447-2454.
-
(2002)
Cancer Res
, vol.62
, pp. 2447-2454
-
-
Duval, A.1
Hamelin, R.2
-
45
-
-
0030870631
-
Germ-line mutation of the hMSH6/GTBP gene in an atypical hereditary nonpolyposis colorectal cancer kindred
-
Akiyama Y., Sato H., Yamada T., Nagasaki H., Tsuchiya A., Abe R., et al. Germ-line mutation of the hMSH6/GTBP gene in an atypical hereditary nonpolyposis colorectal cancer kindred. Cancer Res 1997, 57:3920-3923.
-
(1997)
Cancer Res
, vol.57
, pp. 3920-3923
-
-
Akiyama, Y.1
Sato, H.2
Yamada, T.3
Nagasaki, H.4
Tsuchiya, A.5
Abe, R.6
-
46
-
-
0031278322
-
Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer
-
Miyaki M., Konishi M., Tanaka K., Kikuchi-Yanoshita R., Muraoka M., Yasuno M., et al. Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer. Nat Genet 1997, 17:271-272.
-
(1997)
Nat Genet
, vol.17
, pp. 271-272
-
-
Miyaki, M.1
Konishi, M.2
Tanaka, K.3
Kikuchi-Yanoshita, R.4
Muraoka, M.5
Yasuno, M.6
-
47
-
-
0032749569
-
Germ-line msh6 mutations in colorectal cancer families
-
Kolodner R.D., Tytell J.D., Schmeits J.L., Kane M.F., Gupta R.D., Weger J., et al. Germ-line msh6 mutations in colorectal cancer families. Cancer Res 1999, 59:5068-5074.
-
(1999)
Cancer Res
, vol.59
, pp. 5068-5074
-
-
Kolodner, R.D.1
Tytell, J.D.2
Schmeits, J.L.3
Kane, M.F.4
Gupta, R.D.5
Weger, J.6
-
48
-
-
0001628596
-
Familial endometrial cancer in female carriers of MSH6 germline mutations
-
Wijnen J., de Leeuw W., Vasen H., van der Klift H., Moller P., Stormorken A., et al. Familial endometrial cancer in female carriers of MSH6 germline mutations. Nat Genet 1999, 23:142-144.
-
(1999)
Nat Genet
, vol.23
, pp. 142-144
-
-
Wijnen, J.1
de Leeuw, W.2
Vasen, H.3
van der Klift, H.4
Moller, P.5
Stormorken, A.6
-
49
-
-
76349108011
-
Risks of Lynch syndrome cancers for MSH6 mutation carriers
-
Baglietto L., Lindor N.M., Dowty J.G., White D.M., Wagner A., Gomez Garcia E.B., et al. Risks of Lynch syndrome cancers for MSH6 mutation carriers. J Natl Cancer Inst 2010, 102:193-201.
-
(2010)
J Natl Cancer Inst
, vol.102
, pp. 193-201
-
-
Baglietto, L.1
Lindor, N.M.2
Dowty, J.G.3
White, D.M.4
Wagner, A.5
Gomez Garcia, E.B.6
-
50
-
-
0029868110
-
Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair
-
Marsischky G.T., Filosi N., Kane M.F., Kolodner R. Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair. Genes Dev 1996, 10:407-420.
-
(1996)
Genes Dev
, vol.10
, pp. 407-420
-
-
Marsischky, G.T.1
Filosi, N.2
Kane, M.F.3
Kolodner, R.4
-
51
-
-
0029870366
-
Requirement of the yeast MSH3 and MSH6 genes for MSH2 dependent genomic stability
-
Johnson R.E., Kovvali G.K., Prakash L., Prakash S. Requirement of the yeast MSH3 and MSH6 genes for MSH2 dependent genomic stability. J Biol Chem 1996, 271:7285-7288.
-
(1996)
J Biol Chem
, vol.271
, pp. 7285-7288
-
-
Johnson, R.E.1
Kovvali, G.K.2
Prakash, L.3
Prakash, S.4
-
52
-
-
0031916242
-
Rates of spontaneous mutation
-
Drake J.W., Charlesworth B., Charlesworth D., Crow J.F. Rates of spontaneous mutation. Genetics 1998, 148:1667-1686.
-
(1998)
Genetics
, vol.148
, pp. 1667-1686
-
-
Drake, J.W.1
Charlesworth, B.2
Charlesworth, D.3
Crow, J.F.4
-
53
-
-
0027482444
-
Base selection, proofreading, and mismatch repair during DNA replication in Escherichia coli
-
Schaaper R.M. Base selection, proofreading, and mismatch repair during DNA replication in Escherichia coli. J Biol Chem 1993, 268:23762-23765.
-
(1993)
J Biol Chem
, vol.268
, pp. 23762-23765
-
-
Schaaper, R.M.1
-
54
-
-
0029843192
-
Spontaneous mutators in bacteria: insights into pathways of mutagenesis and repair
-
Miller J.H. Spontaneous mutators in bacteria: insights into pathways of mutagenesis and repair. Annu Rev Microbiol 1996, 50:625-643.
-
(1996)
Annu Rev Microbiol
, vol.50
, pp. 625-643
-
-
Miller, J.H.1
-
55
-
-
0027267249
-
Biochemical basis of DNA replication fidelity
-
Goodman M.F., Creighton S., Bloom L.B., Petruska J. Biochemical basis of DNA replication fidelity. Crit Rev Biochem Mol Biol 1993, 28:83-126.
-
(1993)
Crit Rev Biochem Mol Biol
, vol.28
, pp. 83-126
-
-
Goodman, M.F.1
Creighton, S.2
Bloom, L.B.3
Petruska, J.4
-
57
-
-
77949570420
-
The kinetic and chemical mechanism of high-fidelity DNA polymerases
-
Johnson K.A. The kinetic and chemical mechanism of high-fidelity DNA polymerases. Biochim Biophys Acta 2010, 1804:1041-1048.
-
(2010)
Biochim Biophys Acta
, vol.1804
, pp. 1041-1048
-
-
Johnson, K.A.1
-
58
-
-
38049125552
-
The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases
-
McCulloch S.D., Kunkel T.A. The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases. Cell Res 2008, 18:148-161.
-
(2008)
Cell Res
, vol.18
, pp. 148-161
-
-
McCulloch, S.D.1
Kunkel, T.A.2
-
59
-
-
77957740230
-
Evolving views of DNA replication (in)fidelity
-
Kunkel T.A. Evolving views of DNA replication (in)fidelity. Cold Spring Harb Symp Quant Biol 2009, 74:91-101.
-
(2009)
Cold Spring Harb Symp Quant Biol
, vol.74
, pp. 91-101
-
-
Kunkel, T.A.1
-
61
-
-
77949568225
-
DNA polymerase proofreading: multiple roles maintain genome stability
-
Reha-Krantz L.J. DNA polymerase proofreading: multiple roles maintain genome stability. Biochim Biophys Acta 2010, 1804:1049-1063.
-
(2010)
Biochim Biophys Acta
, vol.1804
, pp. 1049-1063
-
-
Reha-Krantz, L.J.1
-
64
-
-
33644626371
-
DNA mismatch repair: functions and mechanisms
-
Iyer R.R., Pluciennik A., Burdett V., Modrich P.L. DNA mismatch repair: functions and mechanisms. Chem Rev 2006, 106:302-323.
-
(2006)
Chem Rev
, vol.106
, pp. 302-323
-
-
Iyer, R.R.1
Pluciennik, A.2
Burdett, V.3
Modrich, P.L.4
-
65
-
-
33646187811
-
The multifaceted mismatch-repair system
-
Jiricny J. The multifaceted mismatch-repair system. Nat Rev Mol Cell Biol 2006, 7:335-346.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 335-346
-
-
Jiricny, J.1
-
66
-
-
38049125557
-
Mechanisms and functions of DNA mismatch repair
-
Li G.M. Mechanisms and functions of DNA mismatch repair. Cell Res 2008, 18:85-98.
-
(2008)
Cell Res
, vol.18
, pp. 85-98
-
-
Li, G.M.1
-
67
-
-
45449103427
-
DNA mismatch repair: molecular mechanism, cancer, and ageing
-
Hsieh P., Yamane K. DNA mismatch repair: molecular mechanism, cancer, and ageing. Mech Ageing Dev 2008, 129:391-407.
-
(2008)
Mech Ageing Dev
, vol.129
, pp. 391-407
-
-
Hsieh, P.1
Yamane, K.2
-
68
-
-
10944251591
-
Repair and genetic consequences of endogenous DNA base damage in mammalian cells
-
Barnes D.E., Lindahl T. Repair and genetic consequences of endogenous DNA base damage in mammalian cells. Annu Rev Genet 2004, 38:445-476.
-
(2004)
Annu Rev Genet
, vol.38
, pp. 445-476
-
-
Barnes, D.E.1
Lindahl, T.2
-
70
-
-
56749157389
-
Transcription-coupled DNA repair: two decades of progress and surprises
-
Hanawalt P.C., Spivak G. Transcription-coupled DNA repair: two decades of progress and surprises. Nat Rev Mol Cell Biol 2008, 9:958-970.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 958-970
-
-
Hanawalt, P.C.1
Spivak, G.2
-
71
-
-
0004228157
-
-
ASM Press, Washington, DC
-
Friedberg E.C., Walker G.C., Siede W., Wood R.D., Schultz R.A., Ellenberger T. DNA repair and mutagenesis 2006, ASM Press, Washington, DC. 2nd ed.
-
(2006)
DNA repair and mutagenesis
-
-
Friedberg, E.C.1
Walker, G.C.2
Siede, W.3
Wood, R.D.4
Schultz, R.A.5
Ellenberger, T.6
-
72
-
-
0025900035
-
The 3′ to 5′ exonuclease activity located in the DNA polymerase δ subunit of Saccharomyces cerevisiae is required for accurate replication
-
Simon M., Giot L., Faye G. The 3′ to 5′ exonuclease activity located in the DNA polymerase δ subunit of Saccharomyces cerevisiae is required for accurate replication. EMBO J 1991, 10:2163-2170.
-
(1991)
EMBO J
, vol.10
, pp. 2163-2170
-
-
Simon, M.1
Giot, L.2
Faye, G.3
-
73
-
-
0026004621
-
Eukaryotic DNA polymerase amino acid sequence required for 3′→5′ exonuclease activity
-
Morrison A., Bell J.B., Kunkel T.A., Sugino A. Eukaryotic DNA polymerase amino acid sequence required for 3′→5′ exonuclease activity. Proc Natl Acad Sci USA 1991, 88:9473-9477.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 9473-9477
-
-
Morrison, A.1
Bell, J.B.2
Kunkel, T.A.3
Sugino, A.4
-
74
-
-
0027306173
-
Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair
-
Strand M., Prolla T.A., Liskay R.M., Petes T.D. Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair. Nature 1993, 365:274-276.
-
(1993)
Nature
, vol.365
, pp. 274-276
-
-
Strand, M.1
Prolla, T.A.2
Liskay, R.M.3
Petes, T.D.4
-
75
-
-
0027417017
-
Pathway correcting DNA replication errors in Saccharomyces cerevisiae
-
Morrison A., Johnson A.L., Johnston L.H., Sugino A. Pathway correcting DNA replication errors in Saccharomyces cerevisiae. EMBO J 1993, 12:1467-1473.
-
(1993)
EMBO J
, vol.12
, pp. 1467-1473
-
-
Morrison, A.1
Johnson, A.L.2
Johnston, L.H.3
Sugino, A.4
-
76
-
-
0028174896
-
The 3′→5′ exonucleases of both DNA polymerases δ and e{open} participate in correcting errors of DNA replication in Saccharomyces cerevisiae
-
Morrison A., Sugino A. The 3′→5′ exonucleases of both DNA polymerases δ and e{open} participate in correcting errors of DNA replication in Saccharomyces cerevisiae. Mol Gen Genet 1994, 242:289-296.
-
(1994)
Mol Gen Genet
, vol.242
, pp. 289-296
-
-
Morrison, A.1
Sugino, A.2
-
77
-
-
0026335619
-
Exonucleolytic proofreading of leading and lagging strand DNA replication errors
-
Roberts J.D., Thomas D.C., Kunkel T.A. Exonucleolytic proofreading of leading and lagging strand DNA replication errors. Proc Natl Acad Sci USA 1991, 88:3465-3469.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 3465-3469
-
-
Roberts, J.D.1
Thomas, D.C.2
Kunkel, T.A.3
-
78
-
-
0023791605
-
Fidelity of DNA synthesis in a mammalian in vitro replication system
-
Hauser J., Levine A.S., Dixon K. Fidelity of DNA synthesis in a mammalian in vitro replication system. Mol Cell Biol 1988, 8:3267-3271.
-
(1988)
Mol Cell Biol
, vol.8
, pp. 3267-3271
-
-
Hauser, J.1
Levine, A.S.2
Dixon, K.3
-
79
-
-
0027292234
-
An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair
-
Kat A., Thilly W.G., Fang W.-H., Longley M.J., Li G.-M., Modrich P. An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair. Proc Natl Acad Sci USA 1993, 90:6424-6428.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 6424-6428
-
-
Kat, A.1
Thilly, W.G.2
Fang, W.-H.3
Longley, M.J.4
Li, G.-M.5
Modrich, P.6
-
80
-
-
14444268973
-
Mutator phenotype in Msh2-deficient murine embryonic fibroblasts
-
Reitmair A.H., Risley R., Bristow R.G., Wilson T., Ganesh A., Jang A., et al. Mutator phenotype in Msh2-deficient murine embryonic fibroblasts. Cancer Res 1997, 57:3765-3771.
-
(1997)
Cancer Res
, vol.57
, pp. 3765-3771
-
-
Reitmair, A.H.1
Risley, R.2
Bristow, R.G.3
Wilson, T.4
Ganesh, A.5
Jang, A.6
-
81
-
-
0034958108
-
Defective DNA polymerase-δ proofreading causes cancer susceptibility in mice
-
Goldsby R.E., Lawrence N.A., Hays L.E., Olmsted E.A., Chen X., Singh M., et al. Defective DNA polymerase-δ proofreading causes cancer susceptibility in mice. Nat Med 2001, 7:638-639.
-
(2001)
Nat Med
, vol.7
, pp. 638-639
-
-
Goldsby, R.E.1
Lawrence, N.A.2
Hays, L.E.3
Olmsted, E.A.4
Chen, X.5
Singh, M.6
-
82
-
-
0037180555
-
High incidence of epithelial cancers in mice deficient for DNA polymerase δ proofreading
-
Goldsby R.E., Hays L.E., Chen X., Olmsted E.A., Slayton W.B., Spangrude G.J., et al. High incidence of epithelial cancers in mice deficient for DNA polymerase δ proofreading. Proc Natl Acad Sci USA 2002, 99:15560-15565.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 15560-15565
-
-
Goldsby, R.E.1
Hays, L.E.2
Chen, X.3
Olmsted, E.A.4
Slayton, W.B.5
Spangrude, G.J.6
-
83
-
-
70350126567
-
DNA polymerase e{open} and δ proofreading suppress discrete mutator and cancer phenotypes in mice
-
Albertson T.M., Ogawa M., Bugni J.M., Hays L.E., Chen Y., Wang Y., et al. DNA polymerase e{open} and δ proofreading suppress discrete mutator and cancer phenotypes in mice. Proc Natl Acad Sci USA 2009, 106:17101-17104.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 17101-17104
-
-
Albertson, T.M.1
Ogawa, M.2
Bugni, J.M.3
Hays, L.E.4
Chen, Y.5
Wang, Y.6
-
84
-
-
77952523879
-
Case series: acute tumor lysis syndrome in mutator mice with disseminated lymphoblastic lymphoma
-
Treuting P.M., Albertson T.M., Preston B.D. Case series: acute tumor lysis syndrome in mutator mice with disseminated lymphoblastic lymphoma. Toxicol Pathol 2010, 38:476-485.
-
(2010)
Toxicol Pathol
, vol.38
, pp. 476-485
-
-
Treuting, P.M.1
Albertson, T.M.2
Preston, B.D.3
-
85
-
-
34447336941
-
Yeast DNA polymerase e{open} participates in leading-strand DNA replication
-
Pursell Z.F., Isoz I., Lundstrom E.B., Johansson E., Kunkel T.A. Yeast DNA polymerase e{open} participates in leading-strand DNA replication. Science 2007, 317:127-130.
-
(2007)
Science
, vol.317
, pp. 127-130
-
-
Pursell, Z.F.1
Isoz, I.2
Lundstrom, E.B.3
Johansson, E.4
Kunkel, T.A.5
-
86
-
-
42949119884
-
Division of labor at the eukaryotic replication fork
-
Nick McElhinny S.A., Gordenin D.A., Stith C.M., Burgers P.M., Kunkel T.A. Division of labor at the eukaryotic replication fork. Mol Cell 2008, 30:137-144.
-
(2008)
Mol Cell
, vol.30
, pp. 137-144
-
-
Nick McElhinny, S.A.1
Gordenin, D.A.2
Stith, C.M.3
Burgers, P.M.4
Kunkel, T.A.5
-
87
-
-
54249092768
-
Dividing the workload at a eukaryotic replication fork
-
Kunkel T.A., Burgers P.M. Dividing the workload at a eukaryotic replication fork. Trends Cell Biol 2008, 18:521-527.
-
(2008)
Trends Cell Biol
, vol.18
, pp. 521-527
-
-
Kunkel, T.A.1
Burgers, P.M.2
-
88
-
-
0024505072
-
The molecular basis of mutations induced by deoxyribonucleoside triphosphate pool imbalances in mammalian cells
-
Meuth M. The molecular basis of mutations induced by deoxyribonucleoside triphosphate pool imbalances in mammalian cells. Exp Cell Res 1989, 181:305-316.
-
(1989)
Exp Cell Res
, vol.181
, pp. 305-316
-
-
Meuth, M.1
-
89
-
-
0028322120
-
Deoxyribonucleoside triphosphate levels: a critical factor in the maintenance of genetic stability
-
Kunz B.A., Kohalmi S.E., Kunkel T.A., Mathews C.K., McIntosh E.M., Reidy J.A. Deoxyribonucleoside triphosphate levels: a critical factor in the maintenance of genetic stability. Mutat Res 1994, 318:1-64.
-
(1994)
Mutat Res
, vol.318
, pp. 1-64
-
-
Kunz, B.A.1
Kohalmi, S.E.2
Kunkel, T.A.3
Mathews, C.K.4
McIntosh, E.M.5
Reidy, J.A.6
-
90
-
-
33746539166
-
DNA precursor metabolism and genomic stability
-
Mathews C.K. DNA precursor metabolism and genomic stability. FASEB J 2006, 20:1300-1314.
-
(2006)
FASEB J
, vol.20
, pp. 1300-1314
-
-
Mathews, C.K.1
-
91
-
-
0026701365
-
The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine)
-
Michaels M.L., Miller J.H. The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine). J Bacteriol 1992, 174:6321-6325.
-
(1992)
J Bacteriol
, vol.174
, pp. 6321-6325
-
-
Michaels, M.L.1
Miller, J.H.2
-
92
-
-
0028933674
-
Functional cooperation of MutT, MutM and MutY proteins in preventing mutations caused by spontaneous oxidation of guanine nucleotide in Escherichia coli
-
Tajiri T., Maki H., Sekiguchi M. Functional cooperation of MutT, MutM and MutY proteins in preventing mutations caused by spontaneous oxidation of guanine nucleotide in Escherichia coli. Mutat Res 1995, 336:257-267.
-
(1995)
Mutat Res
, vol.336
, pp. 257-267
-
-
Tajiri, T.1
Maki, H.2
Sekiguchi, M.3
-
93
-
-
0037115963
-
Oxidative nucleotide damage: consequences and prevention
-
Sekiguchi M., Tsuzuki T. Oxidative nucleotide damage: consequences and prevention. Oncogene 2002, 21:8895-8904.
-
(2002)
Oncogene
, vol.21
, pp. 8895-8904
-
-
Sekiguchi, M.1
Tsuzuki, T.2
-
94
-
-
34147174320
-
Significance of error-avoiding mechanisms for oxidative DNA damage in carcinogenesis
-
Tsuzuki T., Nakatsu Y., Nakabeppu Y. Significance of error-avoiding mechanisms for oxidative DNA damage in carcinogenesis. Cancer Sci 2007, 98:465-470.
-
(2007)
Cancer Sci
, vol.98
, pp. 465-470
-
-
Tsuzuki, T.1
Nakatsu, Y.2
Nakabeppu, Y.3
-
95
-
-
33845407758
-
Different DNA repair strategies to combat the threat from 8-oxoguanine
-
Russo M.T., De Luca G., Degan P., Bignami M. Different DNA repair strategies to combat the threat from 8-oxoguanine. Mutat Res 2007, 614:69-76.
-
(2007)
Mutat Res
, vol.614
, pp. 69-76
-
-
Russo, M.T.1
De Luca, G.2
Degan, P.3
Bignami, M.4
-
96
-
-
0017222053
-
Bacterial mutator genes and the control of spontaneous mutation
-
Cox E.C. Bacterial mutator genes and the control of spontaneous mutation. Ann Rev Genet 1976, 10:135-156.
-
(1976)
Ann Rev Genet
, vol.10
, pp. 135-156
-
-
Cox, E.C.1
-
97
-
-
0027278557
-
Instability and decay of the primary structure of DNA
-
Lindahl T. Instability and decay of the primary structure of DNA. Nature 1993, 362:709-715.
-
(1993)
Nature
, vol.362
, pp. 709-715
-
-
Lindahl, T.1
-
99
-
-
2942523593
-
Endogenous DNA damage in humans: a review of quantitative data
-
De Bont R., van Larebeke N. Endogenous DNA damage in humans: a review of quantitative data. Mutagenesis 2004, 19:169-185.
-
(2004)
Mutagenesis
, vol.19
, pp. 169-185
-
-
De Bont, R.1
van Larebeke, N.2
-
101
-
-
33845496081
-
Roles of DNA polymerases in replication, repair, and recombination in eukaryotes
-
Pavlov Y.I., Shcherbakova P.V., Rogozin I.B. Roles of DNA polymerases in replication, repair, and recombination in eukaryotes. Int Rev Cytol 2006, 255:41-132.
-
(2006)
Int Rev Cytol
, vol.255
, pp. 41-132
-
-
Pavlov, Y.I.1
Shcherbakova, P.V.2
Rogozin, I.B.3
-
102
-
-
63249130106
-
Polymerase dynamics at the eukaryotic DNA replication fork
-
Burgers P.M. Polymerase dynamics at the eukaryotic DNA replication fork. J Biol Chem 2009, 284:4041-4045.
-
(2009)
J Biol Chem
, vol.284
, pp. 4041-4045
-
-
Burgers, P.M.1
-
103
-
-
0024977355
-
DNA polymerase III, a second essential DNA polymerase, is encoded by the S. cerevisiae CDC2 gene
-
Sitney K.C., Budd M.E., Campbell J.L. DNA polymerase III, a second essential DNA polymerase, is encoded by the S. cerevisiae CDC2 gene. Cell 1989, 56:599-605.
-
(1989)
Cell
, vol.56
, pp. 599-605
-
-
Sitney, K.C.1
Budd, M.E.2
Campbell, J.L.3
-
104
-
-
0024430208
-
Structure and function of the Saccharomyces cerevisiae CDC2 gene encoding the large subunit of DNA polymerase III
-
Boulet A., Simon M., Faye G., Bauer G.A., Burgers P.M.J. Structure and function of the Saccharomyces cerevisiae CDC2 gene encoding the large subunit of DNA polymerase III. EMBO J 1989, 8:1849-1854.
-
(1989)
EMBO J
, vol.8
, pp. 1849-1854
-
-
Boulet, A.1
Simon, M.2
Faye, G.3
Bauer, G.A.4
Burgers, P.M.J.5
-
105
-
-
0033529497
-
Analysis of the essential functions of the C-terminal protein/protein interaction domain of Saccharomyces cerevisiae pol epsilon and its unexpected ability to support growth in the absence of the DNA polymerase domain
-
Dua R., Levy D.L., Campbell J.L. Analysis of the essential functions of the C-terminal protein/protein interaction domain of Saccharomyces cerevisiae pol epsilon and its unexpected ability to support growth in the absence of the DNA polymerase domain. J Biol Chem 1999, 274:22283-22288.
-
(1999)
J Biol Chem
, vol.274
, pp. 22283-22288
-
-
Dua, R.1
Levy, D.L.2
Campbell, J.L.3
-
106
-
-
0034955240
-
Schizosaccharomyces pombe cells lacking the amino-terminal catalytic domains of DNA polymerase epsilon are viable but require the DNA damage checkpoint control
-
Feng W., D'Urso G. Schizosaccharomyces pombe cells lacking the amino-terminal catalytic domains of DNA polymerase epsilon are viable but require the DNA damage checkpoint control. Mol Cell Biol 2001, 21:4495-4504.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 4495-4504
-
-
Feng, W.1
D'Urso, G.2
-
107
-
-
0035942103
-
DNA polymerase e{open} is required for coordinated and efficient chromosomal DNA replication in Xenopus egg extracts
-
Waga S., Masuda T., Takisawa H., Sugino A. DNA polymerase e{open} is required for coordinated and efficient chromosomal DNA replication in Xenopus egg extracts. Proc Natl Acad Sci USA 2001, 98:4978-4983.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 4978-4983
-
-
Waga, S.1
Masuda, T.2
Takisawa, H.3
Sugino, A.4
-
108
-
-
1642351959
-
Distinct roles of DNA polymerases delta and epsilon at the replication fork in Xenopus egg extracts
-
Fukui T., Yamauchi K., Muroya T., Akiyama M., Maki H., Sugino A., et al. Distinct roles of DNA polymerases delta and epsilon at the replication fork in Xenopus egg extracts. Genes Cells 2004, 9:179-191.
-
(2004)
Genes Cells
, vol.9
, pp. 179-191
-
-
Fukui, T.1
Yamauchi, K.2
Muroya, T.3
Akiyama, M.4
Maki, H.5
Sugino, A.6
-
109
-
-
1642545486
-
The protein components and mechanism of eukaryotic Okazaki fragment maturation
-
Kao H.I., Bambara R.A. The protein components and mechanism of eukaryotic Okazaki fragment maturation. Crit Rev Biochem Mol Biol 2003, 38:433-452.
-
(2003)
Crit Rev Biochem Mol Biol
, vol.38
, pp. 433-452
-
-
Kao, H.I.1
Bambara, R.A.2
-
110
-
-
0037040932
-
Human DNA polymerase e{open} colocalizes with proliferating cell nuclear antigen and DNA replication late, but not early, in S phase
-
Fuss J., Linn S. Human DNA polymerase e{open} colocalizes with proliferating cell nuclear antigen and DNA replication late, but not early, in S phase. J Biol Chem 2002, 277:8658-8666.
-
(2002)
J Biol Chem
, vol.277
, pp. 8658-8666
-
-
Fuss, J.1
Linn, S.2
-
111
-
-
0033529791
-
Differential assembly of Cdc45p and DNA polymerases at early and late origins of DNA replication
-
Aparicio O.M., Stout A.M., Bell S.P. Differential assembly of Cdc45p and DNA polymerases at early and late origins of DNA replication. Proc Natl Acad Sci USA 1999, 96:9130-9135.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 9130-9135
-
-
Aparicio, O.M.1
Stout, A.M.2
Bell, S.P.3
-
112
-
-
0034028908
-
Dpb11 controls the association between DNA polymerases alpha and epsilon and the autonomously replicating sequence region of budding yeast
-
Masumoto H., Sugino A., Araki H. Dpb11 controls the association between DNA polymerases alpha and epsilon and the autonomously replicating sequence region of budding yeast. Mol Cell Biol 2000, 20:2809-2817.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 2809-2817
-
-
Masumoto, H.1
Sugino, A.2
Araki, H.3
-
113
-
-
0037847620
-
GINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeast
-
Takayama Y., Kamimura Y., Okawa M., Muramatsu S., Sugino A., Araki H. GINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeast. Genes Dev 2003, 17:1153-1165.
-
(2003)
Genes Dev
, vol.17
, pp. 1153-1165
-
-
Takayama, Y.1
Kamimura, Y.2
Okawa, M.3
Muramatsu, S.4
Sugino, A.5
Araki, H.6
-
114
-
-
0042469481
-
Schizosaccharomyces pombe Dpb2 binds to origin DNA early in S phase and is required for chromosomal DNA replication
-
Feng W., Rodriguez-Menocal L., Tolun G., D'Urso G. Schizosaccharomyces pombe Dpb2 binds to origin DNA early in S phase and is required for chromosomal DNA replication. Mol Biol Cell 2003, 14:3427-3436.
-
(2003)
Mol Biol Cell
, vol.14
, pp. 3427-3436
-
-
Feng, W.1
Rodriguez-Menocal, L.2
Tolun, G.3
D'Urso, G.4
-
115
-
-
0028979332
-
DNA polymerase e{open} links the DNA replication machinery to the S phase checkpoint
-
Navas T.A., Zhou Z., Elledge S.J. DNA polymerase e{open} links the DNA replication machinery to the S phase checkpoint. Cell 1995, 80:29-39.
-
(1995)
Cell
, vol.80
, pp. 29-39
-
-
Navas, T.A.1
Zhou, Z.2
Elledge, S.J.3
-
116
-
-
0037384875
-
Saccharomyces cerevisiae DNA polymerase epsilon and polymerase sigma interact physically and functionally, suggesting a role for polymerase epsilon in sister chromatid cohesion
-
Edwards S., Li C.M., Levy D.L., Brown J., Snow P.M., Campbell J.L. Saccharomyces cerevisiae DNA polymerase epsilon and polymerase sigma interact physically and functionally, suggesting a role for polymerase epsilon in sister chromatid cohesion. Mol Cell Biol 2003, 23:2733-2748.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 2733-2748
-
-
Edwards, S.1
Li, C.M.2
Levy, D.L.3
Brown, J.4
Snow, P.M.5
Campbell, J.L.6
-
117
-
-
0029944855
-
DNA polymerase epsilon may be dispensable for SV40- but not cellular-DNA replication
-
Zlotkin T., Kaufmann G., Jiang Y., Lee M.Y., Uitto L., Syvaoja J., et al. DNA polymerase epsilon may be dispensable for SV40- but not cellular-DNA replication. EMBO J 1996, 15:2298-2305.
-
(1996)
EMBO J
, vol.15
, pp. 2298-2305
-
-
Zlotkin, T.1
Kaufmann, G.2
Jiang, Y.3
Lee, M.Y.4
Uitto, L.5
Syvaoja, J.6
-
118
-
-
33745201206
-
Distinctive activities of DNA polymerases during human DNA replication
-
Rytkönen A.K., Vaara M., Nethanel T., Kaufmann G., Sormunen R., Läärä E., et al. Distinctive activities of DNA polymerases during human DNA replication. FEBS J 2006, 273:2984-3001.
-
(2006)
FEBS J
, vol.273
, pp. 2984-3001
-
-
Rytkönen, A.K.1
Vaara, M.2
Nethanel, T.3
Kaufmann, G.4
Sormunen, R.5
Läärä, E.6
-
119
-
-
0033214791
-
A neutralizing antibody against human DNA polymerase epsilon inhibits cellular but not SV40 DNA replication
-
Pospiech H., Kursula I., Abdel-Aziz W., Malkas L., Uitto L., Kastelli M., et al. A neutralizing antibody against human DNA polymerase epsilon inhibits cellular but not SV40 DNA replication. Nucleic Acids Res 1999, 27:3799-3804.
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 3799-3804
-
-
Pospiech, H.1
Kursula, I.2
Abdel-Aziz, W.3
Malkas, L.4
Uitto, L.5
Kastelli, M.6
-
120
-
-
77954328102
-
Increased mutagenesis and unique mutation signature associated with mitotic gene conversion
-
Hicks W.M., Kim M., Haber J.E. Increased mutagenesis and unique mutation signature associated with mitotic gene conversion. Science 2010, 329:82-85.
-
(2010)
Science
, vol.329
, pp. 82-85
-
-
Hicks, W.M.1
Kim, M.2
Haber, J.E.3
-
121
-
-
0035942104
-
The 3′→5′ exonuclease of DNA polymerase delta can substitute for the 5′ flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability
-
Jin Y.H., Obert R., Burgers P.M., Kunkel T.A., Resnick M.A., Gordenin D.A. The 3′→5′ exonuclease of DNA polymerase delta can substitute for the 5′ flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability. Proc Natl Acad Sci USA 2001, 98:5122-5127.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 5122-5127
-
-
Jin, Y.H.1
Obert, R.2
Burgers, P.M.3
Kunkel, T.A.4
Resnick, M.A.5
Gordenin, D.A.6
-
122
-
-
0037008736
-
The DNA polymerase domain of pole{open} is required for rapid, efficient, and highly accurate chromosomal DNA replication, telomere length maintenance, and normal cell senescence in Saccharomyces cerevisiae
-
Ohya T., Kawasaki Y., Hiraga S., Kanbara S., Nakajo K., Nakashima N., et al. The DNA polymerase domain of pole{open} is required for rapid, efficient, and highly accurate chromosomal DNA replication, telomere length maintenance, and normal cell senescence in Saccharomyces cerevisiae. J Biol Chem 2002, 277:28099-28108.
-
(2002)
J Biol Chem
, vol.277
, pp. 28099-28108
-
-
Ohya, T.1
Kawasaki, Y.2
Hiraga, S.3
Kanbara, S.4
Nakajo, K.5
Nakashima, N.6
-
123
-
-
0030962035
-
Hypermutability of homonucleotide runs in mismatch repair and DNA polymerase proofreading yeast mutants
-
Tran H.T., Keen J.D., Kricker M., Resnick M.A., Gordenin D.A. Hypermutability of homonucleotide runs in mismatch repair and DNA polymerase proofreading yeast mutants. Mol Cell Biol 1997, 17:2859-2865.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 2859-2865
-
-
Tran, H.T.1
Keen, J.D.2
Kricker, M.3
Resnick, M.A.4
Gordenin, D.A.5
-
124
-
-
0032925857
-
Genetic factors affecting the impact of DNA polymerase delta proofreading activity on mutation avoidance in yeast
-
Tran H.T., Degtyareva N.P., Gordenin D.A., Resnick M.A. Genetic factors affecting the impact of DNA polymerase delta proofreading activity on mutation avoidance in yeast. Genetics 1999, 152:47-59.
-
(1999)
Genetics
, vol.152
, pp. 47-59
-
-
Tran, H.T.1
Degtyareva, N.P.2
Gordenin, D.A.3
Resnick, M.A.4
-
125
-
-
0032588388
-
The 3′→5′ exonucleases of DNA polymerases δ and e{open} and the 5′→3′ exonuclease Exo1 have major roles in postreplication mutation avoidance in Saccharomyces cerevisiae
-
Tran H.T., Gordenin D.A., Resnick M.A. The 3′→5′ exonucleases of DNA polymerases δ and e{open} and the 5′→3′ exonuclease Exo1 have major roles in postreplication mutation avoidance in Saccharomyces cerevisiae. Mol Cell Biol 1999, 19:2000-2007.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 2000-2007
-
-
Tran, H.T.1
Gordenin, D.A.2
Resnick, M.A.3
-
126
-
-
0034809479
-
Spontaneous frameshift mutations in Saccharomyces cerevisiae: accumulation during DNA replication and removal by proofreading and mismatch repair activities
-
Greene C.N., Jinks-Robertson S. Spontaneous frameshift mutations in Saccharomyces cerevisiae: accumulation during DNA replication and removal by proofreading and mismatch repair activities. Genetics 2001, 159:65-75.
-
(2001)
Genetics
, vol.159
, pp. 65-75
-
-
Greene, C.N.1
Jinks-Robertson, S.2
-
127
-
-
0034595502
-
Evidence from mutational specificity studies that yeast DNA polymerases δ and e{open} replicate different DNA strands at an intracellular replication fork
-
Karthikeyan R., Vonarx E.J., Straffon A.F., Simon M., Faye G., Kunz B.A. Evidence from mutational specificity studies that yeast DNA polymerases δ and e{open} replicate different DNA strands at an intracellular replication fork. J Mol Biol 2000, 299:405-419.
-
(2000)
J Mol Biol
, vol.299
, pp. 405-419
-
-
Karthikeyan, R.1
Vonarx, E.J.2
Straffon, A.F.3
Simon, M.4
Faye, G.5
Kunz, B.A.6
-
128
-
-
0035053395
-
Stationary-phase mutations in proofreading exonuclease-deficient strains of the yeast Saccharomyces cerevisiae
-
Babudri N., Pavlov Y.I., Matmati N., Ludovisi C., Achilli A. Stationary-phase mutations in proofreading exonuclease-deficient strains of the yeast Saccharomyces cerevisiae. Mol Genet Genomics 2001, 265:362-366.
-
(2001)
Mol Genet Genomics
, vol.265
, pp. 362-366
-
-
Babudri, N.1
Pavlov, Y.I.2
Matmati, N.3
Ludovisi, C.4
Achilli, A.5
-
129
-
-
0029670573
-
3′→5′ exonucleases of DNA polymerases e{open} and δ correct base analog induced DNA replication errors on opposite DNA strands in Saccharomyces cerevisiae
-
Shcherbakova P.V., Pavlov Y.I. 3′→5′ exonucleases of DNA polymerases e{open} and δ correct base analog induced DNA replication errors on opposite DNA strands in Saccharomyces cerevisiae. Genetics 1996, 142:717-726.
-
(1996)
Genetics
, vol.142
, pp. 717-726
-
-
Shcherbakova, P.V.1
Pavlov, Y.I.2
-
130
-
-
3242736410
-
Evidence for interplay among yeast replicative DNA polymerases alpha, delta and epsilon from studies of exonuclease and polymerase active site mutations
-
Pavlov Y.I., Maki S., Maki H., Kunkel T.A. Evidence for interplay among yeast replicative DNA polymerases alpha, delta and epsilon from studies of exonuclease and polymerase active site mutations. BMC Biol 2004, 2:11.
-
(2004)
BMC Biol
, vol.2
, pp. 11
-
-
Pavlov, Y.I.1
Maki, S.2
Maki, H.3
Kunkel, T.A.4
-
131
-
-
30944452765
-
Evidence that errors made by DNA polymerase α are corrected by DNA polymerase δ
-
Pavlov Y.I., Frahm C., Nick McElhinny S.A., Niimi A., Suzuki M., Kunkel T.A. Evidence that errors made by DNA polymerase α are corrected by DNA polymerase δ. Curr Biol 2006, 16:202-207.
-
(2006)
Curr Biol
, vol.16
, pp. 202-207
-
-
Pavlov, Y.I.1
Frahm, C.2
Nick McElhinny, S.A.3
Niimi, A.4
Suzuki, M.5
Kunkel, T.A.6
-
132
-
-
33645006224
-
DNA replication fidelity: proofreading in trans
-
Albertson T.M., Preston B.D. DNA replication fidelity: proofreading in trans. Curr Biol 2006, 16:R209-R211.
-
(2006)
Curr Biol
, vol.16
-
-
Albertson, T.M.1
Preston, B.D.2
-
134
-
-
0032587610
-
DNA polymerase epsilon catalytic domains are dispensable for DNA replication, DNA repair, and cell viability
-
Kesti T., Flick K., Keranen S., Syvaoja J.E., Wittenberg C. DNA polymerase epsilon catalytic domains are dispensable for DNA replication, DNA repair, and cell viability. Mol Cell 1999, 3:679-685.
-
(1999)
Mol Cell
, vol.3
, pp. 679-685
-
-
Kesti, T.1
Flick, K.2
Keranen, S.3
Syvaoja, J.E.4
Wittenberg, C.5
-
135
-
-
0029813614
-
The Saccharomyces cerevisiae Msh2 and Msh6 proteins form a complex that specifically binds to duplex oligonucleotides containing mismatched DNA base pairs
-
Alani E. The Saccharomyces cerevisiae Msh2 and Msh6 proteins form a complex that specifically binds to duplex oligonucleotides containing mismatched DNA base pairs. Mol Cell Biol 1996, 16:5604-5615.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 5604-5615
-
-
Alani, E.1
-
136
-
-
0030465237
-
HMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6
-
Acharya S., Wilson T., Gradia S., Kane M.F., Guerrette S., Marsischky G.T., et al. hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6. Proc Natl Acad Sci USA 1996, 93:13629-13634.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 13629-13634
-
-
Acharya, S.1
Wilson, T.2
Gradia, S.3
Kane, M.F.4
Guerrette, S.5
Marsischky, G.T.6
-
137
-
-
0032584384
-
Isolation of MutSβ from human cells and comparison of the mismatch repair specificities of MutSβ and MutSα
-
Genschel J., Littman S.J., Drummond J.T., Modrich P. Isolation of MutSβ from human cells and comparison of the mismatch repair specificities of MutSβ and MutSα. J Biol Chem 1998, 273:19895-19901.
-
(1998)
J Biol Chem
, vol.273
, pp. 19895-19901
-
-
Genschel, J.1
Littman, S.J.2
Drummond, J.T.3
Modrich, P.4
-
138
-
-
0033578888
-
Biochemical characterization of the interaction between the Saccharomyces cerevisiae MSH2-MSH6 complex and mispaired bases in DNA
-
Marsischky G.T., Kolodner R.D. Biochemical characterization of the interaction between the Saccharomyces cerevisiae MSH2-MSH6 complex and mispaired bases in DNA. J Biol Chem 1999, 274:26668-26682.
-
(1999)
J Biol Chem
, vol.274
, pp. 26668-26682
-
-
Marsischky, G.T.1
Kolodner, R.D.2
-
139
-
-
34548761416
-
Saccharomyces cerevisiae Msh2-Msh3 acts in repair of base-base mispairs
-
Harrington J.M., Kolodner R.D. Saccharomyces cerevisiae Msh2-Msh3 acts in repair of base-base mispairs. Mol Cell Biol 2007, 27:6546-6554.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 6546-6554
-
-
Harrington, J.M.1
Kolodner, R.D.2
-
140
-
-
33746189409
-
Endonucleolytic function of MutLalpha in human mismatch repair
-
Kadyrov F.A., Dzantiev L., Constantin N., Modrich P. Endonucleolytic function of MutLalpha in human mismatch repair. Cell 2006, 126:297-308.
-
(2006)
Cell
, vol.126
, pp. 297-308
-
-
Kadyrov, F.A.1
Dzantiev, L.2
Constantin, N.3
Modrich, P.4
-
141
-
-
34548578984
-
Mutations affecting a putative MutL[alpha] endonuclease motif impact multiple mismatch repair functions
-
Erdeniz N., Nguyen M., Deschenes S.M., Liskay R.M. Mutations affecting a putative MutL[alpha] endonuclease motif impact multiple mismatch repair functions. DNA Repair 2007, 6:1463-1470.
-
(2007)
DNA Repair
, vol.6
, pp. 1463-1470
-
-
Erdeniz, N.1
Nguyen, M.2
Deschenes, S.M.3
Liskay, R.M.4
-
142
-
-
66649124883
-
A possible mechanism for exonuclease 1-independent eukaryotic mismatch repair
-
Kadyrov F.A., Genschel J., Fang Y., Penland E., Edelmann W., Modrich P. A possible mechanism for exonuclease 1-independent eukaryotic mismatch repair. Proc Natl Acad Sci USA 2009, 106:8495-8500.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 8495-8500
-
-
Kadyrov, F.A.1
Genschel, J.2
Fang, Y.3
Penland, E.4
Edelmann, W.5
Modrich, P.6
-
143
-
-
0027502938
-
Defective mismatch binding and a mutator phenotype in cells tolerant to DNA damage
-
Branch P., Aquilina G., Bignami M., Karran P. Defective mismatch binding and a mutator phenotype in cells tolerant to DNA damage. Nature 1993, 362:652-654.
-
(1993)
Nature
, vol.362
, pp. 652-654
-
-
Branch, P.1
Aquilina, G.2
Bignami, M.3
Karran, P.4
-
144
-
-
0035687887
-
Mechanisms of tolerance to DNA damaging therapeutic drugs
-
Karran P. Mechanisms of tolerance to DNA damaging therapeutic drugs. Carcinogenesis 2001, 22:1931-1937.
-
(2001)
Carcinogenesis
, vol.22
, pp. 1931-1937
-
-
Karran, P.1
-
145
-
-
0142123326
-
Mismatch repair and response to DNA-damaging antitumour therapies
-
Bignami M., Casorelli I., Karran P. Mismatch repair and response to DNA-damaging antitumour therapies. Eur J Cancer 2003, 39:2142-2149.
-
(2003)
Eur J Cancer
, vol.39
, pp. 2142-2149
-
-
Bignami, M.1
Casorelli, I.2
Karran, P.3
-
146
-
-
3242885728
-
Mismatch repair and DNA damage signalling
-
Stojic L., Brun R., Jiricny J. Mismatch repair and DNA damage signalling. DNA Repair 2004, 3:1091-1101.
-
(2004)
DNA Repair
, vol.3
, pp. 1091-1101
-
-
Stojic, L.1
Brun, R.2
Jiricny, J.3
-
147
-
-
33645322935
-
Signalling cell cycle arrest and cell death through the MMR System
-
O'Brien V., Brown R. Signalling cell cycle arrest and cell death through the MMR System. Carcinogenesis 2006, 27:682-692.
-
(2006)
Carcinogenesis
, vol.27
, pp. 682-692
-
-
O'Brien, V.1
Brown, R.2
-
148
-
-
33744928856
-
Mismatch repair proteins as sensors of alkylation DNA damage
-
Wang J.Y., Edelmann W. Mismatch repair proteins as sensors of alkylation DNA damage. Cancer Cell 2006, 9:417-418.
-
(2006)
Cancer Cell
, vol.9
, pp. 417-418
-
-
Wang, J.Y.1
Edelmann, W.2
-
149
-
-
2442706833
-
Dependence of the cytotoxicity of DNA-damaging agents on the mismatch repair status of human cells
-
Papouli E., Cejka P., Jiricny J. Dependence of the cytotoxicity of DNA-damaging agents on the mismatch repair status of human cells. Cancer Res 2004, 64:3391-3394.
-
(2004)
Cancer Res
, vol.64
, pp. 3391-3394
-
-
Papouli, E.1
Cejka, P.2
Jiricny, J.3
-
150
-
-
0033607055
-
HMutSα- and hMutLα-dependent phosphorylation of p53 in response to DNA methylator damage
-
Duckett D.R., Bronstein S.M., Taya Y., Modrich P. hMutSα- and hMutLα-dependent phosphorylation of p53 in response to DNA methylator damage. Proc Natl Acad Sci USA 1999, 96:12384-12388.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 12384-12388
-
-
Duckett, D.R.1
Bronstein, S.M.2
Taya, Y.3
Modrich, P.4
-
151
-
-
0037018846
-
The mammalian mismatch repair pathway removes DNA 8-oxodGMP incorporated from the oxidized dNTP pool
-
Colussi C., Parlanti E., Degan P., Aquilina G., Barnes D., Macpherson P., et al. The mammalian mismatch repair pathway removes DNA 8-oxodGMP incorporated from the oxidized dNTP pool. Curr Biol 2002, 12:912-918.
-
(2002)
Curr Biol
, vol.12
, pp. 912-918
-
-
Colussi, C.1
Parlanti, E.2
Degan, P.3
Aquilina, G.4
Barnes, D.5
Macpherson, P.6
-
152
-
-
0033197818
-
MSH2 and MSH6 are required for removal of adenine misincorporated opposite 8-oxo-guanine in S. cerevisiae
-
Ni T.T., Marsischky G.T., Kolodner R.D. MSH2 and MSH6 are required for removal of adenine misincorporated opposite 8-oxo-guanine in S. cerevisiae. Mol Cell 1999, 4:439-444.
-
(1999)
Mol Cell
, vol.4
, pp. 439-444
-
-
Ni, T.T.1
Marsischky, G.T.2
Kolodner, R.D.3
-
153
-
-
0038371133
-
Evidence for preferential mismatch repair of lagging strand DNA replication errors in yeast
-
Pavlov Y.I., Mian I.M., Kunkel T.A. Evidence for preferential mismatch repair of lagging strand DNA replication errors in yeast. Curr Biol 2003, 13:744-748.
-
(2003)
Curr Biol
, vol.13
, pp. 744-748
-
-
Pavlov, Y.I.1
Mian, I.M.2
Kunkel, T.A.3
-
154
-
-
33747341054
-
Mismatch repair-dependent iterative excision at irreparable O6-methylguanine lesions in human nuclear extracts
-
York S.J., Modrich P. Mismatch repair-dependent iterative excision at irreparable O6-methylguanine lesions in human nuclear extracts. J Biol Chem 2006, 281:22674-22683.
-
(2006)
J Biol Chem
, vol.281
, pp. 22674-22683
-
-
York, S.J.1
Modrich, P.2
-
155
-
-
0032726607
-
HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions
-
de Wind N., Dekker M., Claij N., Jansen L., van Klink Y., Radman M., et al. HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions. Nat Genet 1999, 23:359-362.
-
(1999)
Nat Genet
, vol.23
, pp. 359-362
-
-
de Wind, N.1
Dekker, M.2
Claij, N.3
Jansen, L.4
van Klink, Y.5
Radman, M.6
-
156
-
-
0033083377
-
The human MLH1 cDNA complements DNA mismatch repair defects in Mlh1-deficient mouse embryonic fibroblasts
-
Buermeyer A.B., Wilson-Van Patten C., Baker S.M., Liskay R.M. The human MLH1 cDNA complements DNA mismatch repair defects in Mlh1-deficient mouse embryonic fibroblasts. Cancer Res 1999, 59:538-541.
-
(1999)
Cancer Res
, vol.59
, pp. 538-541
-
-
Buermeyer, A.B.1
Wilson-Van Patten, C.2
Baker, S.M.3
Liskay, R.M.4
-
157
-
-
0033168064
-
Apoptosis induced by overexpression of hMSH2 or hMLH1
-
Zhang H., Richards B., Wilson T., Lloyd M., Cranston A., Thorburn A., et al. Apoptosis induced by overexpression of hMSH2 or hMLH1. Cancer Res 1999, 59:3021-3027.
-
(1999)
Cancer Res
, vol.59
, pp. 3021-3027
-
-
Zhang, H.1
Richards, B.2
Wilson, T.3
Lloyd, M.4
Cranston, A.5
Thorburn, A.6
-
158
-
-
33646503204
-
ATR kinase activation mediated by MutSα and MutLα in response to cytotoxic O6-methylguanine adducts
-
Yoshioka K., Yoshioka Y., Hsieh P. ATR kinase activation mediated by MutSα and MutLα in response to cytotoxic O6-methylguanine adducts. Mol Cell 2006, 22:501-510.
-
(2006)
Mol Cell
, vol.22
, pp. 501-510
-
-
Yoshioka, K.1
Yoshioka, Y.2
Hsieh, P.3
-
159
-
-
0033014039
-
Mutator phenotypes of yeast strains heterozygous for mutations in the MSH2 gene
-
Drotschmann K., Clark A.B., Tran H.T., Resnick M.A., Gordenin D.A., Kunkel T.A. Mutator phenotypes of yeast strains heterozygous for mutations in the MSH2 gene. Proc Natl Acad Sci USA 1999, 96:2970-2975.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 2970-2975
-
-
Drotschmann, K.1
Clark, A.B.2
Tran, H.T.3
Resnick, M.A.4
Gordenin, D.A.5
Kunkel, T.A.6
-
160
-
-
0034130841
-
EXO1 and MSH6 are high-copy suppressors of conditional mutations in the MSH2 mismatch repair gene of Saccharomyces cerevisiae
-
Sokolsky T., Alani E. EXO1 and MSH6 are high-copy suppressors of conditional mutations in the MSH2 mismatch repair gene of Saccharomyces cerevisiae. Genetics 2000, 155:589-599.
-
(2000)
Genetics
, vol.155
, pp. 589-599
-
-
Sokolsky, T.1
Alani, E.2
-
161
-
-
0030271999
-
Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis
-
Umar A., Buermeyer A.B., Simon J.A., Thomas D.C., Clark A.B., Liskay R.M., et al. Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis. Cell 1996, 87:65-73.
-
(1996)
Cell
, vol.87
, pp. 65-73
-
-
Umar, A.1
Buermeyer, A.B.2
Simon, J.A.3
Thomas, D.C.4
Clark, A.B.5
Liskay, R.M.6
-
162
-
-
0034711275
-
Functional interaction of proliferating cell nuclear antigen with MSH2-MSH6 and MSH2-MSH3 complexes
-
Clark A.B., Valle F., Drotschmann K., Gary R.K., Kunkel T.A. Functional interaction of proliferating cell nuclear antigen with MSH2-MSH6 and MSH2-MSH3 complexes. J Biol Chem 2000, 275:36498-36501.
-
(2000)
J Biol Chem
, vol.275
, pp. 36498-36501
-
-
Clark, A.B.1
Valle, F.2
Drotschmann, K.3
Gary, R.K.4
Kunkel, T.A.5
-
163
-
-
0034958793
-
Exo1-Dependent mutator mutations: model system for studying functional interactions in mismatch repair
-
Amin N.S., Nguyen M.N., Oh S., Kolodner R.D. exo1-Dependent mutator mutations: model system for studying functional interactions in mismatch repair. Mol Cell Biol 2001, 21:5142-5155.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 5142-5155
-
-
Amin, N.S.1
Nguyen, M.N.2
Oh, S.3
Kolodner, R.D.4
-
164
-
-
0037414642
-
Transfer of the MSH2·MSH6 complex from proliferating cell nuclear antigen to mispaired bases in DNA
-
Lau P.J., Kolodner R.D. Transfer of the MSH2·MSH6 complex from proliferating cell nuclear antigen to mispaired bases in DNA. J Biol Chem 2003, 278:14-17.
-
(2003)
J Biol Chem
, vol.278
, pp. 14-17
-
-
Lau, P.J.1
Kolodner, R.D.2
-
165
-
-
0036345594
-
Yeast origins establish a strand bias for replicational mutagenesis
-
Pavlov Y.I., Newlon C.S., Kunkel T.A. Yeast origins establish a strand bias for replicational mutagenesis. Mol Cell 2002, 10:207-213.
-
(2002)
Mol Cell
, vol.10
, pp. 207-213
-
-
Pavlov, Y.I.1
Newlon, C.S.2
Kunkel, T.A.3
-
166
-
-
42649124572
-
The biochemistry of somatic hypermutation
-
Peled J.U., Kuang F.L., Iglesias-Ussel M.D., Roa S., Kalis S.L., Goodman M.F., et al. The biochemistry of somatic hypermutation. Annu Rev Immunol 2008, 26:481-511.
-
(2008)
Annu Rev Immunol
, vol.26
, pp. 481-511
-
-
Peled, J.U.1
Kuang, F.L.2
Iglesias-Ussel, M.D.3
Roa, S.4
Kalis, S.L.5
Goodman, M.F.6
-
167
-
-
30344455023
-
Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage Version 7
-
Friedberg E.C., Meira L.B. Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage Version 7. DNA Repair (Amst) 2006, 5:189-209.
-
(2006)
DNA Repair (Amst)
, vol.5
, pp. 189-209
-
-
Friedberg, E.C.1
Meira, L.B.2
-
168
-
-
0036303398
-
Mouse models for human DNA mismatch-repair gene defects
-
Wei K., Kucherlapati R., Edelmann W. Mouse models for human DNA mismatch-repair gene defects. Trends Mol Med 2002, 8:346-353.
-
(2002)
Trends Mol Med
, vol.8
, pp. 346-353
-
-
Wei, K.1
Kucherlapati, R.2
Edelmann, W.3
-
170
-
-
24944549950
-
Deletion of XPC leads to lung tumors in mice and is associated with early events in human lung carcinogenesis
-
Hollander M.C., Philburn R.T., Patterson A.D., Velasco-Miguel S., Friedberg E.C., Linnoila R.I., et al. Deletion of XPC leads to lung tumors in mice and is associated with early events in human lung carcinogenesis. Proc Natl Acad Sci USA 2005, 102:13200-13205.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 13200-13205
-
-
Hollander, M.C.1
Philburn, R.T.2
Patterson, A.D.3
Velasco-Miguel, S.4
Friedberg, E.C.5
Linnoila, R.I.6
-
171
-
-
0035949687
-
Spontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGTPase
-
Tsuzuki T., Egashira A., Igarashi H., Iwakuma T., Nakatsuru Y., Tominaga Y., et al. Spontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGTPase. Proc Natl Acad Sci USA 2001, 98:11456-11461.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 11456-11461
-
-
Tsuzuki, T.1
Egashira, A.2
Igarashi, H.3
Iwakuma, T.4
Nakatsuru, Y.5
Tominaga, Y.6
-
172
-
-
0037374556
-
Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption
-
Sakumi K., Tominaga Y., Furuichi M., Xu P., Tsuzuki T., Sekiguchi M., et al. Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption. Cancer Res 2003, 63:902-905.
-
(2003)
Cancer Res
, vol.63
, pp. 902-905
-
-
Sakumi, K.1
Tominaga, Y.2
Furuichi, M.3
Xu, P.4
Tsuzuki, T.5
Sekiguchi, M.6
-
173
-
-
2342520175
-
Deficiencies in mouse Myh and Ogg1 result in tumor predisposition and G to T mutations in codon 12 of the K-ras oncogene in lung tumors
-
Xie Y., Yang H., Cunanan C., Okamoto K., Shibata D., Pan J., et al. Deficiencies in mouse Myh and Ogg1 result in tumor predisposition and G to T mutations in codon 12 of the K-ras oncogene in lung tumors. Cancer Res 2004, 64:3096-3102.
-
(2004)
Cancer Res
, vol.64
, pp. 3096-3102
-
-
Xie, Y.1
Yang, H.2
Cunanan, C.3
Okamoto, K.4
Shibata, D.5
Pan, J.6
-
174
-
-
34547105083
-
MUTYH-null mice are susceptible to spontaneous and oxidative stress induced intestinal tumorigenesis
-
Sakamoto K., Tominaga Y., Yamauchi K., Nakatsu Y., Sakumi K., Yoshiyama K., et al. MUTYH-null mice are susceptible to spontaneous and oxidative stress induced intestinal tumorigenesis. Cancer Res 2007, 67:6599-6604.
-
(2007)
Cancer Res
, vol.67
, pp. 6599-6604
-
-
Sakamoto, K.1
Tominaga, Y.2
Yamauchi, K.3
Nakatsu, Y.4
Sakumi, K.5
Yoshiyama, K.6
-
175
-
-
0035796024
-
Cancer predisposition in mutant mice defective in multiple genetic pathways: uncovering important genetic interactions
-
Meira L.B., Reis A.M., Cheo D.L., Nahari D., Burns D.K., Friedberg E.C. Cancer predisposition in mutant mice defective in multiple genetic pathways: uncovering important genetic interactions. Mutat Res 2001, 477:51-58.
-
(2001)
Mutat Res
, vol.477
, pp. 51-58
-
-
Meira, L.B.1
Reis, A.M.2
Cheo, D.L.3
Nahari, D.4
Burns, D.K.5
Friedberg, E.C.6
-
176
-
-
31544443220
-
Increased susceptibility to UV-induced skin carcinogenesis in polymerase eta-deficient mice
-
Lin Q., Clark A.B., McCulloch S.D., Yuan T., Bronson R.T., Kunkel T.A., et al. Increased susceptibility to UV-induced skin carcinogenesis in polymerase eta-deficient mice. Cancer Res 2006, 66:87-94.
-
(2006)
Cancer Res
, vol.66
, pp. 87-94
-
-
Lin, Q.1
Clark, A.B.2
McCulloch, S.D.3
Yuan, T.4
Bronson, R.T.5
Kunkel, T.A.6
-
177
-
-
33749602964
-
UV-B radiation induces epithelial tumors in mice lacking DNA polymerase eta and mesenchymal tumors in mice deficient for DNA polymerase iota
-
Ohkumo T., Kondo Y., Yokoi M., Tsukamoto T., Yamada A., Sugimoto T., et al. UV-B radiation induces epithelial tumors in mice lacking DNA polymerase eta and mesenchymal tumors in mice deficient for DNA polymerase iota. Mol Cell Biol 2006, 26:7696-7706.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 7696-7706
-
-
Ohkumo, T.1
Kondo, Y.2
Yokoi, M.3
Tsukamoto, T.4
Yamada, A.5
Sugimoto, T.6
-
178
-
-
0030480945
-
Synergistic interactions between XPC and p53 mutations in double-mutant mice: neural tube abnormalities and accelerated UV radiation-induced skin cancer
-
Cheo D.L., Meira L.B., Hammer R.E., Burns D.K., Doughty A.T., Friedberg E.C. Synergistic interactions between XPC and p53 mutations in double-mutant mice: neural tube abnormalities and accelerated UV radiation-induced skin cancer. Curr Biol 1996, 6:1691-1694.
-
(1996)
Curr Biol
, vol.6
, pp. 1691-1694
-
-
Cheo, D.L.1
Meira, L.B.2
Hammer, R.E.3
Burns, D.K.4
Doughty, A.T.5
Friedberg, E.C.6
-
179
-
-
0034654169
-
Ultraviolet B radiation-induced skin cancer in mice defective in the Xpc, Trp53, and Apex (HAP1) genes: genotype-specific effects on cancer predisposition and pathology of tumors
-
Cheo D.L., Meira L.B., Burns D.K., Reis A.M., Issac T., Friedberg E.C. Ultraviolet B radiation-induced skin cancer in mice defective in the Xpc, Trp53, and Apex (HAP1) genes: genotype-specific effects on cancer predisposition and pathology of tumors. Cancer Res 2000, 60:1580-1584.
-
(2000)
Cancer Res
, vol.60
, pp. 1580-1584
-
-
Cheo, D.L.1
Meira, L.B.2
Burns, D.K.3
Reis, A.M.4
Issac, T.5
Friedberg, E.C.6
-
180
-
-
0031254043
-
Genetic interaction between HAP1/REF-1 and p53
-
Meira L.B., Cheo D.L., Hammer R.E., Burns D.K., Reis A., Friedberg E.C. Genetic interaction between HAP1/REF-1 and p53. Nat Genet 1997, 17:145.
-
(1997)
Nat Genet
, vol.17
, pp. 145
-
-
Meira, L.B.1
Cheo, D.L.2
Hammer, R.E.3
Burns, D.K.4
Reis, A.5
Friedberg, E.C.6
-
181
-
-
0036837527
-
Mice defective in the mismatch repair gene Msh2 show increased predisposition to UVB radiation-induced skin cancer
-
Meira L.B., Cheo D.L., Reis A.M., Claij N., Burns D.K., te Riele H., et al. Mice defective in the mismatch repair gene Msh2 show increased predisposition to UVB radiation-induced skin cancer. DNA Repair 2002, 1:929-934.
-
(2002)
DNA Repair
, vol.1
, pp. 929-934
-
-
Meira, L.B.1
Cheo, D.L.2
Reis, A.M.3
Claij, N.4
Burns, D.K.5
te Riele, H.6
-
182
-
-
0033539610
-
Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage
-
Klungland A., Rosewell I., Hollenbach S., Larsen E., Daly G., Epe B., et al. Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage. Proc Natl Acad Sci USA 1999, 96:13300-13305.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 13300-13305
-
-
Klungland, A.1
Rosewell, I.2
Hollenbach, S.3
Larsen, E.4
Daly, G.5
Epe, B.6
-
183
-
-
12944252969
-
Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyguanine in mice
-
Minowa O., Arai T., Hirano M., Monden Y., Nakai S., Fukuda M., et al. Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyguanine in mice. Proc Natl Acad Sci USA 2000, 97:4156-4161.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 4156-4161
-
-
Minowa, O.1
Arai, T.2
Hirano, M.3
Monden, Y.4
Nakai, S.5
Fukuda, M.6
-
184
-
-
0029101616
-
Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer
-
de Wind N., Dekker M., Berns A., Radman M., te Riele H. Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer. Cell 1995, 82:321-330.
-
(1995)
Cell
, vol.82
, pp. 321-330
-
-
de Wind, N.1
Dekker, M.2
Berns, A.3
Radman, M.4
te Riele, H.5
-
185
-
-
0031882250
-
Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair
-
Prolla T.A., Baker S.M., Harris A.C., Tsao J.L., Yao X., Bronner C.E., et al. Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair. Nat Genet 1998, 18:276-279.
-
(1998)
Nat Genet
, vol.18
, pp. 276-279
-
-
Prolla, T.A.1
Baker, S.M.2
Harris, A.C.3
Tsao, J.L.4
Yao, X.5
Bronner, C.E.6
-
186
-
-
9444271133
-
Spontaneous intestinal carcinomas and skin neoplasms in Msh2-deficient mice
-
Reitmair A.H., Redston M., Cai J.C., Chuang T.C., Bjerknes M., Cheng H., et al. Spontaneous intestinal carcinomas and skin neoplasms in Msh2-deficient mice. Cancer Res 1996, 56:3842-3849.
-
(1996)
Cancer Res
, vol.56
, pp. 3842-3849
-
-
Reitmair, A.H.1
Redston, M.2
Cai, J.C.3
Chuang, T.C.4
Bjerknes, M.5
Cheng, H.6
-
187
-
-
0030861695
-
Base transitions dominate the mutational spectrum of a transgenic reporter gene in MSH2 deficient mice
-
Andrew S.E., Reitmair A.H., Fox J., Hsiao L., Francis A., McKinnon M., et al. Base transitions dominate the mutational spectrum of a transgenic reporter gene in MSH2 deficient mice. Oncogene 1997, 15:123-129.
-
(1997)
Oncogene
, vol.15
, pp. 123-129
-
-
Andrew, S.E.1
Reitmair, A.H.2
Fox, J.3
Hsiao, L.4
Francis, A.5
McKinnon, M.6
-
188
-
-
0035253196
-
Elevated mutant frequencies and increased C:G→T:A transitions in Mlh1-/- versus Pms2-/- murine small intestinal epithelial cells
-
Baross-Francis A., Makhani N., Liskay R.M., Jirik F.R. Elevated mutant frequencies and increased C:G→T:A transitions in Mlh1-/- versus Pms2-/- murine small intestinal epithelial cells. Oncogene 2001, 20:619-625.
-
(2001)
Oncogene
, vol.20
, pp. 619-625
-
-
Baross-Francis, A.1
Makhani, N.2
Liskay, R.M.3
Jirik, F.R.4
-
189
-
-
0033923814
-
Mutagenesis in PMS2- and MSH2-deficient mice indicates differential protection from transversions and frameshifts
-
Andrew S.E., Xu X.S., Baross-Francis A., Narayanan L., Milhausen K., Liskay R.M., et al. Mutagenesis in PMS2- and MSH2-deficient mice indicates differential protection from transversions and frameshifts. Carcinogenesis 2000, 21:1291-1295.
-
(2000)
Carcinogenesis
, vol.21
, pp. 1291-1295
-
-
Andrew, S.E.1
Xu, X.S.2
Baross-Francis, A.3
Narayanan, L.4
Milhausen, K.5
Liskay, R.M.6
-
190
-
-
33845354122
-
Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6
-
Hegan D.C., Narayanan L., Jirik F.R., Edelmann W., Liskay R.M., Glazer P.M. Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6. Carcinogenesis 2006, 27:2402-2408.
-
(2006)
Carcinogenesis
, vol.27
, pp. 2402-2408
-
-
Hegan, D.C.1
Narayanan, L.2
Jirik, F.R.3
Edelmann, W.4
Liskay, R.M.5
Glazer, P.M.6
-
191
-
-
0035886816
-
The selection for mismatch repair defects in hereditary nonpolyposis colorectal cancer: revising the mutator hypothesis
-
Fishel R. The selection for mismatch repair defects in hereditary nonpolyposis colorectal cancer: revising the mutator hypothesis. Cancer Res 2001, 61:7369-7374.
-
(2001)
Cancer Res
, vol.61
, pp. 7369-7374
-
-
Fishel, R.1
-
192
-
-
5144220638
-
Dominant effects of an Msh6 missense mutation on DNA repair and cancer susceptibility
-
Yang G., Scherer S.J., Shell S.S., Yang K., Kim M., Lipkin M., et al. Dominant effects of an Msh6 missense mutation on DNA repair and cancer susceptibility. Cancer Cell 2004, 6:139-150.
-
(2004)
Cancer Cell
, vol.6
, pp. 139-150
-
-
Yang, G.1
Scherer, S.J.2
Shell, S.S.3
Yang, K.4
Kim, M.5
Lipkin, M.6
-
193
-
-
9144227402
-
An Msh2 point mutation uncouples DNA mismatch repair and apoptosis
-
Lin D.P., Wang Y., Scherer S.J., Clark A.B., Yang K., Avdievich E., et al. An Msh2 point mutation uncouples DNA mismatch repair and apoptosis. Cancer Res 2004, 64:517-522.
-
(2004)
Cancer Res
, vol.64
, pp. 517-522
-
-
Lin, D.P.1
Wang, Y.2
Scherer, S.J.3
Clark, A.B.4
Yang, K.5
Avdievich, E.6
-
194
-
-
0029061638
-
Mismatch repair deficiency in phenotypically normal human cells
-
Parsons R., Li G.-M., Longley M., Modrich P., Liu B., Berk T., et al. Mismatch repair deficiency in phenotypically normal human cells. Science 1995, 268:738-740.
-
(1995)
Science
, vol.268
, pp. 738-740
-
-
Parsons, R.1
Li, G.-M.2
Longley, M.3
Modrich, P.4
Liu, B.5
Berk, T.6
-
195
-
-
19944401050
-
The multiple biological roles of the 3′→5′ exonuclease of Saccharomyces cerevisiae DNA polymerase delta require switching between the polymerase and exonuclease domains
-
Jin Y.H., Garg P., Stith C.M., Al-Refai H., Sterling J.F., Murray L.J., et al. The multiple biological roles of the 3′→5′ exonuclease of Saccharomyces cerevisiae DNA polymerase delta require switching between the polymerase and exonuclease domains. Mol Cell Biol 2005, 25:461-471.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 461-471
-
-
Jin, Y.H.1
Garg, P.2
Stith, C.M.3
Al-Refai, H.4
Sterling, J.F.5
Murray, L.J.6
-
196
-
-
34047132773
-
DNA polymerase delta-dependent repair of DNA single strand breaks containing 3′-end proximal lesions
-
Parsons J.L., Preston B.D., O'Connor T.R., Dianov G.L. DNA polymerase delta-dependent repair of DNA single strand breaks containing 3′-end proximal lesions. Nucleic Acids Res 2007, 35:1054-1063.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 1054-1063
-
-
Parsons, J.L.1
Preston, B.D.2
O'Connor, T.R.3
Dianov, G.L.4
-
197
-
-
43249113327
-
Proofreading activity of DNA polymerase Pol2 mediates 3′-end processing during nonhomologous end joining in yeast
-
Tseng S.F., Gabriel A., Teng S.C. Proofreading activity of DNA polymerase Pol2 mediates 3′-end processing during nonhomologous end joining in yeast. PLoS Genet 2008, 4:e1000060.
-
(2008)
PLoS Genet
, vol.4
-
-
Tseng, S.F.1
Gabriel, A.2
Teng, S.C.3
-
198
-
-
0346363763
-
Noncompetitive counteractions of DNA polymerase e{open} and ISW2/yCHRAC for epigenetic inheritance of telomere position effect in Saccharomyces cerevisiae
-
Iida T., Araki H. Noncompetitive counteractions of DNA polymerase e{open} and ISW2/yCHRAC for epigenetic inheritance of telomere position effect in Saccharomyces cerevisiae. Mol Cell Biol 2004, 24:217-227.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 217-227
-
-
Iida, T.1
Araki, H.2
-
199
-
-
33644856609
-
Molecular models for the tissue specificity of DNA mismatch repair-deficient carcinogenesis
-
Chao E.C., Lipkin S.M. Molecular models for the tissue specificity of DNA mismatch repair-deficient carcinogenesis. Nucleic Acids Res 2006, 34:840-852.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 840-852
-
-
Chao, E.C.1
Lipkin, S.M.2
-
201
-
-
47649100711
-
DNA polymerases and human disease
-
Loeb L.A., Monnat R.J. DNA polymerases and human disease. Nat Rev Genet 2008, 9:594-604.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 594-604
-
-
Loeb, L.A.1
Monnat, R.J.2
-
202
-
-
33645216188
-
Mutator phenotypes caused by substitution at a conserved motif A residue in eukaryotic DNA polymerase δ
-
Venkatesan R.N., Hsu J.J., Lawrence N.A., Preston B.D., Loeb L.A. Mutator phenotypes caused by substitution at a conserved motif A residue in eukaryotic DNA polymerase δ. J Biol Chem 2006, 281:4486-4494.
-
(2006)
J Biol Chem
, vol.281
, pp. 4486-4494
-
-
Venkatesan, R.N.1
Hsu, J.J.2
Lawrence, N.A.3
Preston, B.D.4
Loeb, L.A.5
-
203
-
-
35648999490
-
Mutation at the polymerase active site of mouse DNA polymerase δ increases genomic instability and accelerates tumorigenesis
-
Venkatesan R.N., Treuting P.M., Fuller E.D., Goldsby R.E., Norwood T.H., Gooley T.A., et al. Mutation at the polymerase active site of mouse DNA polymerase δ increases genomic instability and accelerates tumorigenesis. Mol Cell Biol 2007, 27:7669-7682.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 7669-7682
-
-
Venkatesan, R.N.1
Treuting, P.M.2
Fuller, E.D.3
Goldsby, R.E.4
Norwood, T.H.5
Gooley, T.A.6
-
204
-
-
0024562306
-
Human DNA polymerase alpha: predicted functional domains and relationships with viral DNA polymerases
-
Wang T.S., Wong S.W., Korn D. Human DNA polymerase alpha: predicted functional domains and relationships with viral DNA polymerases. FASEB J 1989, 3:14-21.
-
(1989)
FASEB J
, vol.3
, pp. 14-21
-
-
Wang, T.S.1
Wong, S.W.2
Korn, D.3
-
205
-
-
65349186567
-
Evolution of DNA polymerases: an inactivated polymerase-exonuclease module in Pol epsilon and a chimeric origin of eukaryotic polymerases from two classes of archaeal ancestors
-
Tahirov T.H., Makarova K.S., Rogozin I.B., Pavlov Y.I., Koonin E.V. Evolution of DNA polymerases: an inactivated polymerase-exonuclease module in Pol epsilon and a chimeric origin of eukaryotic polymerases from two classes of archaeal ancestors. Biol Direct 2009, 4:11.
-
(2009)
Biol Direct
, vol.4
, pp. 11
-
-
Tahirov, T.H.1
Makarova, K.S.2
Rogozin, I.B.3
Pavlov, Y.I.4
Koonin, E.V.5
-
206
-
-
76349101664
-
A cancer-associated DNA polymerase δ variant modeled in yeast causes a catastrophic increase in genomic instability
-
Daee D.L., Mertz T.M., Shcherbakova P.V. A cancer-associated DNA polymerase δ variant modeled in yeast causes a catastrophic increase in genomic instability. Proc Natl Acad Sci USA 2010, 107:157-162.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 157-162
-
-
Daee, D.L.1
Mertz, T.M.2
Shcherbakova, P.V.3
-
207
-
-
78651103864
-
Comprehensive screen of genetic variation in DNA repair pathway genes and postmenopausal breast cancer risk
-
Monsees G.M., Kraft P., Chanock S.J., Hunter D.J., Han J. Comprehensive screen of genetic variation in DNA repair pathway genes and postmenopausal breast cancer risk. Breast Cancer Res Treat 2010, 10.1007/s10549-010-0947-3.
-
(2010)
Breast Cancer Res Treat
-
-
Monsees, G.M.1
Kraft, P.2
Chanock, S.J.3
Hunter, D.J.4
Han, J.5
-
208
-
-
77952504856
-
Common genetic variants and risk for HPV persistence and progression to cervical cancer
-
Wang S.S., Gonzalez P., Yu K., Porras C., Li Q., Safaeian M., et al. Common genetic variants and risk for HPV persistence and progression to cervical cancer. PLoS One 2010, 5:e8667.
-
(2010)
PLoS One
, vol.5
-
-
Wang, S.S.1
Gonzalez, P.2
Yu, K.3
Porras, C.4
Li, Q.5
Safaeian, M.6
-
209
-
-
34548724426
-
Genetic variation in the DNA repair genes is predictive of outcome in lung cancer
-
Matakidou A., el Galta R., Webb E.L., Rudd M.F., Bridle H., Eisen T., et al. Genetic variation in the DNA repair genes is predictive of outcome in lung cancer. Hum Mol Genet 2007, 16:2333-2340.
-
(2007)
Hum Mol Genet
, vol.16
, pp. 2333-2340
-
-
Matakidou, A.1
el Galta, R.2
Webb, E.L.3
Rudd, M.F.4
Bridle, H.5
Eisen, T.6
-
210
-
-
39649123998
-
Comprehensive analysis of DNA repair gene variants and risk of meningioma
-
Bethke L., Murray A., Webb E., Schoemaker M., Muir K., McKinney P., et al. Comprehensive analysis of DNA repair gene variants and risk of meningioma. J Natl Cancer Inst 2008, 100:270-276.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 270-276
-
-
Bethke, L.1
Murray, A.2
Webb, E.3
Schoemaker, M.4
Muir, K.5
McKinney, P.6
-
211
-
-
3042829470
-
Kin-cohort estimates for familial breast cancer risk in relation to variants in DNA base excision repair, BRCA1 interacting and growth factor genes
-
Sigurdson A.J., Hauptmann M., Chatterjee N., Alexander B.H., Doody M.M., Rutter J.L., et al. Kin-cohort estimates for familial breast cancer risk in relation to variants in DNA base excision repair, BRCA1 interacting and growth factor genes. BMC Cancer 2004, 4:9.
-
(2004)
BMC Cancer
, vol.4
, pp. 9
-
-
Sigurdson, A.J.1
Hauptmann, M.2
Chatterjee, N.3
Alexander, B.H.4
Doody, M.M.5
Rutter, J.L.6
-
212
-
-
56049099006
-
Polygenic model of DNA repair genetic polymorphisms in human breast cancer risk
-
Smith T.R., Levine E.A., Freimanis R.I., Akman S.A., Allen G.O., Hoang K.N., et al. Polygenic model of DNA repair genetic polymorphisms in human breast cancer risk. Carcinogenesis 2008, 29:2132-2138.
-
(2008)
Carcinogenesis
, vol.29
, pp. 2132-2138
-
-
Smith, T.R.1
Levine, E.A.2
Freimanis, R.I.3
Akman, S.A.4
Allen, G.O.5
Hoang, K.N.6
-
213
-
-
33344464252
-
Bladder cancer predisposition: a multigenic approach to DNA-repair and cell-cycle-control genes
-
Wu X., Gu J., Grossman H.B., Amos C.I., Etzel C., Huang M., et al. Bladder cancer predisposition: a multigenic approach to DNA-repair and cell-cycle-control genes. Am J Hum Genet 2006, 78:464-479.
-
(2006)
Am J Hum Genet
, vol.78
, pp. 464-479
-
-
Wu, X.1
Gu, J.2
Grossman, H.B.3
Amos, C.I.4
Etzel, C.5
Huang, M.6
-
214
-
-
0028859670
-
Polymerase δ variants in RER colorectal tumours
-
da Costa L.T., Liu B., el-Deiry W., Hamilton S.R., Kinzler K.W., Vogelstein B., et al. Polymerase δ variants in RER colorectal tumours. Nat Genet 1995, 9:10-11.
-
(1995)
Nat Genet
, vol.9
, pp. 10-11
-
-
da Costa, L.T.1
Liu, B.2
el-Deiry, W.3
Hamilton, S.R.4
Kinzler, K.W.5
Vogelstein, B.6
-
215
-
-
0033559182
-
Detection of mutations in the DNA polymerase δ gene of human sporadic colorectal cancers and colon cancer cell lines
-
Flohr T., Dai J.C., Buttner J., Popanda O., Hagmuller E., Thielmann H.W. Detection of mutations in the DNA polymerase δ gene of human sporadic colorectal cancers and colon cancer cell lines. Int J Cancer 1999, 80:919-929.
-
(1999)
Int J Cancer
, vol.80
, pp. 919-929
-
-
Flohr, T.1
Dai, J.C.2
Buttner, J.3
Popanda, O.4
Hagmuller, E.5
Thielmann, H.W.6
-
216
-
-
0032712407
-
A mutation detected in DNA polymerase δ cDNA from Novikoff hepatoma cells correlates with abnormal catalytic properties of the enzyme
-
Popanda O., Flohr T., Fox G., Thielmann H.W. A mutation detected in DNA polymerase δ cDNA from Novikoff hepatoma cells correlates with abnormal catalytic properties of the enzyme. J Cancer Res Clin Oncol 1999, 125:598-608.
-
(1999)
J Cancer Res Clin Oncol
, vol.125
, pp. 598-608
-
-
Popanda, O.1
Flohr, T.2
Fox, G.3
Thielmann, H.W.4
-
217
-
-
0028989875
-
DNA polymerases α, δ, and e{open} of Novikoff hepatoma cells differ from those of normal rat liver in physicochemical and catalytic properties
-
Popanda O., Fox G., Thielmann H.W. DNA polymerases α, δ, and e{open} of Novikoff hepatoma cells differ from those of normal rat liver in physicochemical and catalytic properties. J Mol Med 1995, 73:259-268.
-
(1995)
J Mol Med
, vol.73
, pp. 259-268
-
-
Popanda, O.1
Fox, G.2
Thielmann, H.W.3
-
218
-
-
0030029818
-
Preferential inhibition of DNA polymerases α, δ, and e{open} from Novikoff hepatoma cells by inhibitors of cell proliferation
-
Fox G., Popanda O., Edler L., Thielmann H.W. Preferential inhibition of DNA polymerases α, δ, and e{open} from Novikoff hepatoma cells by inhibitors of cell proliferation. J Cancer Res Clin Oncol 1996, 122:78-94.
-
(1996)
J Cancer Res Clin Oncol
, vol.122
, pp. 78-94
-
-
Fox, G.1
Popanda, O.2
Edler, L.3
Thielmann, H.W.4
-
219
-
-
0031440040
-
Evidence for reduced copying fidelity of DNA polymerases α, δ, and e{open} from Novikoff hepatoma cells
-
Fox G., Popanda O., Thielmann H.W. Evidence for reduced copying fidelity of DNA polymerases α, δ, and e{open} from Novikoff hepatoma cells. J Cancer Res Clin Oncol 1997, 123:659-668.
-
(1997)
J Cancer Res Clin Oncol
, vol.123
, pp. 659-668
-
-
Fox, G.1
Popanda, O.2
Thielmann, H.W.3
-
220
-
-
0033800646
-
Increased rates of genomic deletions generated by mutations in the yeast gene encoding DNA polymerase δ or by decreases in the cellular levels of DNA polymerase δ
-
Kokoska R.J., Stefanovic L., DeMai J., Petes T.D. Increased rates of genomic deletions generated by mutations in the yeast gene encoding DNA polymerase δ or by decreases in the cellular levels of DNA polymerase δ. Mol Cell Biol 2000, 20:7490-7504.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 7490-7504
-
-
Kokoska, R.J.1
Stefanovic, L.2
DeMai, J.3
Petes, T.D.4
-
221
-
-
28544438284
-
Alterations of DNA and chromatin structures at telomeres and genetic instability in mouse cells defective in DNA polymerase alpha
-
Nakamura M., Nabetani A., Mizuno T., Hanaoka F., Ishikawa F. Alterations of DNA and chromatin structures at telomeres and genetic instability in mouse cells defective in DNA polymerase alpha. Mol Cell Biol 2005, 25:11073-11088.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 11073-11088
-
-
Nakamura, M.1
Nabetani, A.2
Mizuno, T.3
Hanaoka, F.4
Ishikawa, F.5
-
222
-
-
14844286404
-
Chromosomal translocations in yeast induced by low levels of DNA polymerase: a model for chromosome fragile sites
-
Lemoine F.J., Degtyareva N.P., Lobachev K., Petes T.D. Chromosomal translocations in yeast induced by low levels of DNA polymerase: a model for chromosome fragile sites. Cell 2005, 120:587-598.
-
(2005)
Cell
, vol.120
, pp. 587-598
-
-
Lemoine, F.J.1
Degtyareva, N.P.2
Lobachev, K.3
Petes, T.D.4
-
223
-
-
46249112206
-
Low levels of DNA polymerase alpha induce mitotic and meiotic instability in the ribosomal DNA gene cluster of Saccharomyces cerevisiae
-
Casper A.M., Mieczkowski P.A., Gawel M., Petes T.D. Low levels of DNA polymerase alpha induce mitotic and meiotic instability in the ribosomal DNA gene cluster of Saccharomyces cerevisiae. PLoS Genet 2008, 4:e1000105.
-
(2008)
PLoS Genet
, vol.4
-
-
Casper, A.M.1
Mieczkowski, P.A.2
Gawel, M.3
Petes, T.D.4
-
224
-
-
50249159576
-
Reduced levels of DNA polymerase δ induce chromosome fragile site instability in yeast
-
Lemoine F.J., Degtyareva N.P., Kokoska R.J., Petes T.D. Reduced levels of DNA polymerase δ induce chromosome fragile site instability in yeast. Mol Cell Biol 2008, 28:5359-5368.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 5359-5368
-
-
Lemoine, F.J.1
Degtyareva, N.P.2
Kokoska, R.J.3
Petes, T.D.4
-
225
-
-
0034805293
-
In vivo consequences of putative active site mutations in yeast DNA polymerases α, e{open}, δ, and ζ
-
Pavlov Y.I., Shcherbakova P.V., Kunkel T.A. In vivo consequences of putative active site mutations in yeast DNA polymerases α, e{open}, δ, and ζ. Genetics 2001, 159:47-64.
-
(2001)
Genetics
, vol.159
, pp. 47-64
-
-
Pavlov, Y.I.1
Shcherbakova, P.V.2
Kunkel, T.A.3
-
226
-
-
0142055081
-
Highly conserved region of the catalytic subunit of DNA polymerase epsilon in human breast cancer
-
Zhou Q., Elzagheid A., Jalava P., Sundfors C., Huang D., Syväoja J.E., et al. Highly conserved region of the catalytic subunit of DNA polymerase epsilon in human breast cancer. Exp Oncol 2003, 25:206-210.
-
(2003)
Exp Oncol
, vol.25
, pp. 206-210
-
-
Zhou, Q.1
Elzagheid, A.2
Jalava, P.3
Sundfors, C.4
Huang, D.5
Syväoja, J.E.6
-
227
-
-
57149136067
-
Genomic changes of the 55kDa subunit of DNA polymerase epsilon in human breast cancer
-
Zhou Q., Effati R., Talvinen K., Pospiech H., Syväoja J.E., Collan Y. Genomic changes of the 55kDa subunit of DNA polymerase epsilon in human breast cancer. Cancer Genomics Proteomics 2008, 5:287-292.
-
(2008)
Cancer Genomics Proteomics
, vol.5
, pp. 287-292
-
-
Zhou, Q.1
Effati, R.2
Talvinen, K.3
Pospiech, H.4
Syväoja, J.E.5
Collan, Y.6
-
228
-
-
76749088088
-
Mutations/polymorphisms in the 55kDa subunit of DNA polymerase epsilon in human colorectal cancer
-
Zhou Q., Talvinen K., Sundstrom J., Elzagheid A., Pospiech H., Syvaoja J.E., et al. Mutations/polymorphisms in the 55kDa subunit of DNA polymerase epsilon in human colorectal cancer. Cancer Genomics Proteomics 2009, 6:297-304.
-
(2009)
Cancer Genomics Proteomics
, vol.6
, pp. 297-304
-
-
Zhou, Q.1
Talvinen, K.2
Sundstrom, J.3
Elzagheid, A.4
Pospiech, H.5
Syvaoja, J.E.6
-
229
-
-
77954139443
-
Genomic analysis of the 55kDa subunit of DNA polymerase epsilon in human intracranial neoplasms
-
Zhou Q., Lehtonen T., Lehtonen J., Laakso S., Szymas J., Pospiech H., et al. Genomic analysis of the 55kDa subunit of DNA polymerase epsilon in human intracranial neoplasms. Cancer Genomics Proteomics 2010, 7:143-146.
-
(2010)
Cancer Genomics Proteomics
, vol.7
, pp. 143-146
-
-
Zhou, Q.1
Lehtonen, T.2
Lehtonen, J.3
Laakso, S.4
Szymas, J.5
Pospiech, H.6
-
230
-
-
0001769577
-
Über mehrpolige Mitosen als Mittel zur Analyze des Zellkerns
-
Boveri T. Über mehrpolige Mitosen als Mittel zur Analyze des Zellkerns. Verh Dtsch Zool Ges Würzburg 1902, 35:67-90.
-
(1902)
Verh Dtsch Zool Ges Würzburg
, vol.35
, pp. 67-90
-
-
Boveri, T.1
-
231
-
-
0035495858
-
Cancer genetics: from Boveri and Mendel to microarrays
-
Balmain A. Cancer genetics: from Boveri and Mendel to microarrays. Nat Rev Cancer 2001, 1:77-82.
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 77-82
-
-
Balmain, A.1
-
232
-
-
0033614998
-
Creation of human tumour cells with defined genetic elements
-
Hahn W.C., Counter C.M., Lundberg A.S., Beijersbergen R.L., Brooks M.W., Weinberg R.A. Creation of human tumour cells with defined genetic elements. Nature 1999, 400:464-468.
-
(1999)
Nature
, vol.400
, pp. 464-468
-
-
Hahn, W.C.1
Counter, C.M.2
Lundberg, A.S.3
Beijersbergen, R.L.4
Brooks, M.W.5
Weinberg, R.A.6
-
233
-
-
0037079003
-
Rules for making human tumor cells
-
Hahn W.C., Weinberg R.A. Rules for making human tumor cells. N Engl J Med 2002, 347:1593-1603.
-
(2002)
N Engl J Med
, vol.347
, pp. 1593-1603
-
-
Hahn, W.C.1
Weinberg, R.A.2
-
234
-
-
77951139631
-
Genome remodelling in a basal-like breast cancer metastasis and xenograft
-
Ding L., Ellis M.J., Li S., Larson D.E., Chen K., Wallis J.W., et al. Genome remodelling in a basal-like breast cancer metastasis and xenograft. Nature 2010, 464:999-1005.
-
(2010)
Nature
, vol.464
, pp. 999-1005
-
-
Ding, L.1
Ellis, M.J.2
Li, S.3
Larson, D.E.4
Chen, K.5
Wallis, J.W.6
-
235
-
-
77953006634
-
The mutation spectrum revealed by paired genome sequences from a lung cancer patient
-
Lee W., Jiang Z., Liu J., Haverty P.M., Guan Y., Stinson J., et al. The mutation spectrum revealed by paired genome sequences from a lung cancer patient. Nature 2010, 465:473-477.
-
(2010)
Nature
, vol.465
, pp. 473-477
-
-
Lee, W.1
Jiang, Z.2
Liu, J.3
Haverty, P.M.4
Guan, Y.5
Stinson, J.6
-
236
-
-
74449093973
-
A comprehensive catalogue of somatic mutations from a human cancer genome
-
Pleasance E.D., Cheetham R.K., Stephens P.J., McBride D.J., Humphray S.J., Greenman C.D., et al. A comprehensive catalogue of somatic mutations from a human cancer genome. Nature 2010, 463:191-196.
-
(2010)
Nature
, vol.463
, pp. 191-196
-
-
Pleasance, E.D.1
Cheetham, R.K.2
Stephens, P.J.3
McBride, D.J.4
Humphray, S.J.5
Greenman, C.D.6
-
237
-
-
74449085934
-
A small-cell lung cancer genome with complex signatures of tobacco exposure
-
Pleasance E.D., Stephens P.J., O'Meara S., McBride D.J., Meynert A., Jones D., et al. A small-cell lung cancer genome with complex signatures of tobacco exposure. Nature 2010, 463:184-190.
-
(2010)
Nature
, vol.463
, pp. 184-190
-
-
Pleasance, E.D.1
Stephens, P.J.2
O'Meara, S.3
McBride, D.J.4
Meynert, A.5
Jones, D.6
-
238
-
-
67449152488
-
Cancer genome sequencing-an interim analysis
-
Fox E.J., Salk J.J., Loeb L.A. Cancer genome sequencing-an interim analysis. Cancer Res 2009, 69:4948-4950.
-
(2009)
Cancer Res
, vol.69
, pp. 4948-4950
-
-
Fox, E.J.1
Salk, J.J.2
Loeb, L.A.3
-
239
-
-
75749100093
-
Mutational heterogeneity in human cancers: origin and consequences
-
Salk J.J., Fox E.J., Loeb L.A. Mutational heterogeneity in human cancers: origin and consequences. Annu Rev Pathol 2010, 5:51-75.
-
(2010)
Annu Rev Pathol
, vol.5
, pp. 51-75
-
-
Salk, J.J.1
Fox, E.J.2
Loeb, L.A.3
-
240
-
-
1542374198
-
Problems of somatic mutation and cancer
-
Frank S.A., Nowak M.A. Problems of somatic mutation and cancer. Bioessays 2004, 26:291-299.
-
(2004)
Bioessays
, vol.26
, pp. 291-299
-
-
Frank, S.A.1
Nowak, M.A.2
|