-
1
-
-
0035850251
-
Molecular mechanisms of DNA mismatch repair
-
Hsieh P. Molecular mechanisms of DNA mismatch repair. Mutat. Res. 486:2001;71-87
-
(2001)
Mutat. Res.
, vol.486
, pp. 71-87
-
-
Hsieh, P.1
-
2
-
-
0032538880
-
Replication errors: Cha(ll)enging the genome
-
Jiricny J. Replication errors: cha(ll)enging the genome. EMBO J. 17:1998;6427-6436
-
(1998)
EMBO J.
, vol.17
, pp. 6427-6436
-
-
Jiricny, J.1
-
3
-
-
0142123326
-
Mismatch repair and response to DNA-damaging antitumour therapies
-
Bignami M., Casorelli I., Karran P. Mismatch repair and response to DNA-damaging antitumour therapies. Eur. J. Cancer. 39:2003;2142-2149
-
(2003)
Eur. J. Cancer
, vol.39
, pp. 2142-2149
-
-
Bignami, M.1
Casorelli, I.2
Karran, P.3
-
4
-
-
0345357346
-
DNA mismatch repair and cancer
-
Li G.M. DNA mismatch repair and cancer. Front. Biosci. 8:2003;997-1017
-
(2003)
Front. Biosci.
, vol.8
, pp. 997-1017
-
-
Li, G.M.1
-
6
-
-
0034113805
-
Suppression of spontaneous mutagenesis in human cells by DNA base excision-repair
-
Lindahl T. Suppression of spontaneous mutagenesis in human cells by DNA base excision-repair. Mutat. Res. 462:2000;129-135
-
(2000)
Mutat. Res.
, vol.462
, pp. 129-135
-
-
Lindahl, T.1
-
8
-
-
0029659046
-
HMutSbeta, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA
-
Palombo F., Iaccarino I., Nakajima E., Ikejima M., Shimada T., Jiricny J. hMutSbeta, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA. Curr. Biol. 6:1996;1181-1184
-
(1996)
Curr. Biol.
, vol.6
, pp. 1181-1184
-
-
Palombo, F.1
Iaccarino, I.2
Nakajima, E.3
Ikejima, M.4
Shimada, T.5
Jiricny, J.6
-
9
-
-
0032555141
-
Mismatch repair deficiency associated with overexpression of the MSH3 gene
-
Marra G., Iaccarino I., Lettieri T., Roscilli G., Delmastro P., Jiricny J. Mismatch repair deficiency associated with overexpression of the MSH3 gene. Proc. Natl. Acad. Sci. U.S.A. 95:1998;8568-8573
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 8568-8573
-
-
Marra, G.1
Iaccarino, I.2
Lettieri, T.3
Roscilli, G.4
Delmastro, P.5
Jiricny, J.6
-
10
-
-
0034695488
-
Mutation of the magnesium binding site of hMSH6 disables the hMutS-alpha sliding clamp from translocating along DNA
-
Iaccarino I., Marra G., Dufner P., Jiricny J. Mutation of the magnesium binding site of hMSH6 disables the hMutS-alpha sliding clamp from translocating along DNA. J. Biol. Chem. 275:2000;2080-2086
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 2080-2086
-
-
Iaccarino, I.1
Marra, G.2
Dufner, P.3
Jiricny, J.4
-
11
-
-
0033083040
-
HMSH2-hMSH6 forms a hydrolysis-independent sliding clamp on mismatched DNA
-
Gradia S., Subramanian D., Wilson T., Acharya S., Makhov A., Griffith J., Fishel R. hMSH2-hMSH6 forms a hydrolysis-independent sliding clamp on mismatched DNA. Mol. Cell. 3:1999;255-261
-
(1999)
Mol. Cell
, vol.3
, pp. 255-261
-
-
Gradia, S.1
Subramanian, D.2
Wilson, T.3
Acharya, S.4
Makhov, A.5
Griffith, J.6
Fishel, R.7
-
12
-
-
0033610878
-
Nucleotide-promoted release of hMutSalpha from heteroduplex DNA is consistent with an ATP-dependent translocation mechanism
-
Blackwell L.J., Martik D., Bjornson K.P., Bjomson E.S., Modrich P. Nucleotide-promoted release of hMutSalpha from heteroduplex DNA is consistent with an ATP-dependent translocation mechanism. J. Biol. Chem. 273:1998;32055-32062
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 32055-32062
-
-
Blackwell, L.J.1
Martik, D.2
Bjornson, K.P.3
Bjomson, E.S.4
Modrich, P.5
-
13
-
-
0028941627
-
Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs
-
Li G.M., Modrich P. Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs. Proc. Natl. Acad. Sci. U.S.A. 92:1995;1950-1954
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 1950-1954
-
-
Li, G.M.1
Modrich, P.2
-
14
-
-
0025340001
-
Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines
-
Holmes J.J., Clark S., Modrich P. Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines. Proc. Natl. Acad. Sci. U.S.A. 87:1990;5837-5841
-
(1990)
Proc. Natl. Acad. Sci. U.S.A.
, vol.87
, pp. 5837-5841
-
-
Holmes, J.J.1
Clark, S.2
Modrich, P.3
-
15
-
-
0345276522
-
Mechanism of 5′-directed excision in human mismatch repair
-
Genschel J., Modrich P. Mechanism of 5′-directed excision in human mismatch repair. Mol. Cell. 12:2003;1077-1086
-
(2003)
Mol. Cell
, vol.12
, pp. 1077-1086
-
-
Genschel, J.1
Modrich, P.2
-
16
-
-
0027269844
-
Human strand-specific mismatch repair occurs by a bidirectional mechanism similar to that of the bacterial reaction
-
Fang W.H., Modrich P. Human strand-specific mismatch repair occurs by a bidirectional mechanism similar to that of the bacterial reaction. J. Biol. Chem. 268:1993;11838-11844
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 11838-11844
-
-
Fang, W.H.1
Modrich, P.2
-
17
-
-
0032723363
-
Signaling mismatch repair in cancer
-
Fishel R. Signaling mismatch repair in cancer. Nat. Med. 5:1999;1239-1241
-
(1999)
Nat. Med.
, vol.5
, pp. 1239-1241
-
-
Fishel, R.1
-
18
-
-
3042841883
-
A defined human system that supports bidirectional mismatch-provoked excision
-
Dzantiev L., Constantin N., Genschel J., Iyer R.R., Burgers P.M., Modrich P. A defined human system that supports bidirectional mismatch-provoked excision. Mol. Cell. 15:2004;31-41
-
(2004)
Mol. Cell
, vol.15
, pp. 31-41
-
-
Dzantiev, L.1
Constantin, N.2
Genschel, J.3
Iyer, R.R.4
Burgers, P.M.5
Modrich, P.6
-
19
-
-
0036007071
-
Functional analysis of MLH1 mutations linked to hereditary nonpolyposis colon cancer
-
Nystrom-Lahti M., Perrera C., Raschle M., Panyushkina-Seiler E., Marra G., Curci A., Quaresima B., Costanzo F., D'Urso M., Venuta S., Jiricny J. Functional analysis of MLH1 mutations linked to hereditary nonpolyposis colon cancer. Genes Chromosomes Cancer. 33:2002;160-167
-
(2002)
Genes Chromosomes Cancer
, vol.33
, pp. 160-167
-
-
Nystrom-Lahti, M.1
Perrera, C.2
Raschle, M.3
Panyushkina-Seiler, E.4
Marra, G.5
Curci, A.6
Quaresima, B.7
Costanzo, F.8
D'Urso, M.9
Venuta, S.10
Jiricny, J.11
-
20
-
-
0037077309
-
Mutations within the hMLHl and hPMS2 subunits of the human MutLalpha mismatch repair factor affect its ATPase activity, but not its ability to interact with hMutSalpha
-
Raschle M., Dufner P., Marra G., Jiricny J. Mutations within the hMLHl and hPMS2 subunits of the human MutLalpha mismatch repair factor affect its ATPase activity, but not its ability to interact with hMutSalpha. J. Biol. Chem. 277:2002;21810-21820
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 21810-21820
-
-
Raschle, M.1
Dufner, P.2
Marra, G.3
Jiricny, J.4
-
21
-
-
0034500024
-
DNA mismatch repair and genetic instability
-
Harfe B.D., Jinks-Robertson S. DNA mismatch repair and genetic instability. Ann. Rev. Genet. 34:2000;359-399
-
(2000)
Ann. Rev. Genet.
, vol.34
, pp. 359-399
-
-
Harfe, B.D.1
Jinks-Robertson, S.2
-
22
-
-
0035111895
-
Recent progress in the biology, chemistry and structural biology of DNA glycosylases
-
Scharer O.D., Jiricny J. Recent progress in the biology, chemistry and structural biology of DNA glycosylases. Bioessays. 23:2001;270-281
-
(2001)
Bioessays
, vol.23
, pp. 270-281
-
-
Scharer, O.D.1
Jiricny, J.2
-
23
-
-
0020332947
-
6-methylguanine residues in E. coli DNA
-
6- methylguanine residues in E. coli DNA. Nature. 296:1982;868-869
-
(1982)
Nature
, vol.296
, pp. 868-869
-
-
Karran, P.1
Marinus, M.G.2
-
24
-
-
0035687887
-
Mechanisms of tolerance to DNA damaging therapeutic drugs
-
Karran P. Mechanisms of tolerance to DNA damaging therapeutic drugs. Carcinogenesis. 22:2001;1931-1937
-
(2001)
Carcinogenesis
, vol.22
, pp. 1931-1937
-
-
Karran, P.1
-
25
-
-
0029665878
-
4-methylthymine, or the cisplatin-d(GpG) adduct
-
4-methylthymine, or the cisplatin-d(GpG) adduct. Proc. Natl. Acad. Sci. U.S.A. 93:1996;6443-6447
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 6443-6447
-
-
Duckett, D.R.1
Drummond, J.T.2
Murchie, A.I.3
Reardon, J.T.4
Sancar, A.5
Lilley, D.M.6
Modrich, P.7
-
29
-
-
0037881803
-
Methylation-induced G(2)/M arrest requires a full complement of the mismatch repair protein hMLHl
-
Cejka P., Stojic L., Mojas N., Russell A.M., Heinimann K., Cannavo E., di Pietro M., Marra G., Jiricny J. Methylation-induced G(2)/M arrest requires a full complement of the mismatch repair protein hMLHl. EMBO J. 22:2003;2245-2254
-
(2003)
EMBO J.
, vol.22
, pp. 2245-2254
-
-
Cejka, P.1
Stojic, L.2
Mojas, N.3
Russell, A.M.4
Heinimann, K.5
Cannavo, E.6
Di Pietro, M.7
Marra, G.8
Jiricny, J.9
-
30
-
-
0347364654
-
MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation
-
Wang Y., Qin J. MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation. Proc. Natl. Acad. Sci. U.S.A. 100:2003;15387-15392
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 15387-15392
-
-
Wang, Y.1
Qin, J.2
-
31
-
-
0035941021
-
ATR and ATRIP: Partners in checkpoint signaling
-
Cortez D., Guntuku S., Qin J., Elledge S.J. ATR and ATRIP: partners in checkpoint signaling. Science. 294:2001;1713-1716
-
(2001)
Science
, vol.294
, pp. 1713-1716
-
-
Cortez, D.1
Guntuku, S.2
Qin, J.3
Elledge, S.J.4
-
32
-
-
0037567268
-
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
-
Zou L., Elledge S.J. Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science. 300:2003;1542-1548
-
(2003)
Science
, vol.300
, pp. 1542-1548
-
-
Zou, L.1
Elledge, S.J.2
-
33
-
-
0035577796
-
Replication protein A2 phosphorylation after DNA damage by the coordinated action of Ataxia telangiectasia-mutated and DNA-dependent protein kinase
-
Wang H., Guan J., Perrault A.R., Wang Y., Iliakis G. Replication protein A2 phosphorylation after DNA damage by the coordinated action of Ataxia telangiectasia-mutated and DNA-dependent protein kinase. Cancer Res. 61:2001;8554-8563
-
(2001)
Cancer Res.
, vol.61
, pp. 8554-8563
-
-
Wang, H.1
Guan, J.2
Perrault, A.R.3
Wang, Y.4
Iliakis, G.5
-
34
-
-
1342325347
-
Replication protein a (RPA) phosphorylation prevents RPA association with replication centers
-
Vassin V.M., Wold M.S., Borowiec J.A. Replication protein A (RPA) phosphorylation prevents RPA association with replication centers. Mol. Cell Biol. 24:2004;1930-1943
-
(2004)
Mol. Cell Biol.
, vol.24
, pp. 1930-1943
-
-
Vassin, V.M.1
Wold, M.S.2
Borowiec, J.A.3
-
35
-
-
0347364654
-
MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation
-
Wang Y., Qin J. MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation. Proc. Natl. Acad. Sci. U.S.A. 100:2003;15387-15392
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 15387-15392
-
-
Wang, Y.1
Qin, J.2
-
36
-
-
0015132710
-
A novel mechanism for the inhibition of DNA synthesis following methylation: The effect of N-methyl-N-nitrosourea on HeLa cells
-
Plant J.E., Roberts J.J. A novel mechanism for the inhibition of DNA synthesis following methylation: the effect of N-methyl-N-nitrosourea on HeLa cells. Chem. Biol. Interact. 3:1971;337-342
-
(1971)
Chem. Biol. Interact.
, vol.3
, pp. 337-342
-
-
Plant, J.E.1
Roberts, J.J.2
-
38
-
-
0032480042
-
Critical steps in alkylation-induced aberration formation
-
Kaina B. Critical steps in alkylation-induced aberration formation. Mutat. Res. 404:1998;119-124
-
(1998)
Mutat. Res.
, vol.404
, pp. 119-124
-
-
Kaina, B.1
-
40
-
-
0037064053
-
ATM is activated in response to N-methyl-N′-nitro-N- nitrosoguanidine-induced DNA alkylation
-
Adamson A.W., Kim W.J., Shangary S., Baskaran R., Brown K.D. ATM is activated in response to N-methyl-N′-nitro-N-nitrosoguanidine-induced DNA alkylation. J. Biol. Chem. 277:2002;38222-38229
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 38222-38229
-
-
Adamson, A.W.1
Kim, W.J.2
Shangary, S.3
Baskaran, R.4
Brown, K.D.5
-
41
-
-
0030015770
-
Competency in mismatch repair prohibits clonal expansion of cancer cells treated with N-methyl-N′-nitro-N-nitrosoguanidine
-
Carethers J.M., Hawn M.T., Chauhan D.P., Luce M.C., Marra G., Koi M., Boland C.R. Competency in mismatch repair prohibits clonal expansion of cancer cells treated with N-methyl-N′-nitro-N-nitrosoguanidine. J. Clin. Invest. 98:1996;199-206
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 199-206
-
-
Carethers, J.M.1
Hawn, M.T.2
Chauhan, D.P.3
Luce, M.C.4
Marra, G.5
Koi, M.6
Boland, C.R.7
-
42
-
-
1542358851
-
Loss of ATM sensitizes against 06-methylguanine triggered apoptosis, SCEs and chromosomal aberrations
-
Debiak M., Nikolova T., Kaina B. Loss of ATM sensitizes against 06-methylguanine triggered apoptosis, SCEs and chromosomal aberrations. DNA Repair (Amst). 3:2004;359-368
-
(2004)
DNA Repair (Amst)
, vol.3
, pp. 359-368
-
-
Debiak, M.1
Nikolova, T.2
Kaina, B.3
-
43
-
-
0034141562
-
The controlling role of ATM in homologous recombinational repair of DNA damage
-
Morrison C., Sonoda E., Takao N., Shinohara A., Yamamoto K., Takeda S. The controlling role of ATM in homologous recombinational repair of DNA damage. EMBO J. 19:2000;463-471
-
(2000)
EMBO J.
, vol.19
, pp. 463-471
-
-
Morrison, C.1
Sonoda, E.2
Takao, N.3
Shinohara, A.4
Yamamoto, K.5
Takeda, S.6
-
44
-
-
0242663968
-
The p38 mitogen-activated protein kinase pathway links the DNA mismatch repair system to the G2 checkpoint and to resistance to chemotherapeutic DNA-methylating agents
-
Hirose Y., Katayama M., Stokoe D., Haas-Kogan D.A., Berger M.S., Pieper R.O. The p38 mitogen-activated protein kinase pathway links the DNA mismatch repair system to the G2 checkpoint and to resistance to chemotherapeutic DNA-methylating agents. Mol. Cell Biol. 23:2003;8306-8315
-
(2003)
Mol. Cell Biol.
, vol.23
, pp. 8306-8315
-
-
Hirose, Y.1
Katayama, M.2
Stokoe, D.3
Haas-Kogan, D.A.4
Berger, M.S.5
Pieper, R.O.6
-
45
-
-
0035449355
-
Cell cycle checkpoint signaling through the ATM and ATR kinases
-
Abraham R.T. Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev. 15:2001;2177-2196
-
(2001)
Genes Dev.
, vol.15
, pp. 2177-2196
-
-
Abraham, R.T.1
-
46
-
-
0029822592
-
Role of postreplicative DNA mismatch repair in the cytotoxic action of thioguanine
-
Swann P.F., Waters T.R., Moulton D.C., Xu Y.Z., Zheng Q., Edwards M., Mace R. Role of postreplicative DNA mismatch repair in the cytotoxic action of thioguanine. Science. 273:1996;1109-1111
-
(1996)
Science
, vol.273
, pp. 1109-1111
-
-
Swann, P.F.1
Waters, T.R.2
Moulton, D.C.3
Xu, Y.Z.4
Zheng, Q.5
Edwards, M.6
MacE, R.7
-
47
-
-
0029143992
-
Evidence for a connection between the mismatch repair system and the G2 cell cycle checkpoint
-
Hawn M.T., Umar A., Carethers J.M., Marra G., Kunkel T.A., Boland C.R., Koi M. Evidence for a connection between the mismatch repair system and the G2 cell cycle checkpoint. Cancer Res. 55:1995;3721-3725
-
(1995)
Cancer Res.
, vol.55
, pp. 3721-3725
-
-
Hawn, M.T.1
Umar, A.2
Carethers, J.M.3
Marra, G.4
Kunkel, T.A.5
Boland, C.R.6
Koi, M.7
-
48
-
-
0033083377
-
The human MLH1 cDNA complements DNA mismatch repair defects in Mlhl-deficient mouse embryonic fibroblasts
-
Buermeyer A.B., Wilson-Van Patten C., Baker S.M., Liskay R.M. The human MLH1 cDNA complements DNA mismatch repair defects in Mlhl-deficient mouse embryonic fibroblasts. Cancer Res. 59:1999;538-541
-
(1999)
Cancer Res.
, vol.59
, pp. 538-541
-
-
Buermeyer, A.B.1
Wilson-Van Patten, C.2
Baker, S.M.3
Liskay, R.M.4
-
49
-
-
0037837443
-
DNA mismatch repair (MMR) mediates 6-thioguanine genotoxicity by introducing single-strand breaks to signal a G(2)-M arrest in MMR-proficient RKO cells
-
Yan T., Berry S.E., Desai A.B., Kinsella T.J. DNA mismatch repair (MMR) mediates 6-thioguanine genotoxicity by introducing single-strand breaks to signal a G(2)-M arrest in MMR-proficient RKO cells. Clin. Cancer Res. 9:2003;2327-2334
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 2327-2334
-
-
Yan, T.1
Berry, S.E.2
Desai, A.B.3
Kinsella, T.J.4
-
50
-
-
0025040536
-
Characterization of the DNA damage in 6-thioguanine-treated cells
-
Pan B.F., Nelson J.A. Characterization of the DNA damage in 6-thioguanine-treated cells. Biochem. Pharmacol. 40:1990;1063-1069
-
(1990)
Biochem. Pharmacol.
, vol.40
, pp. 1063-1069
-
-
Pan, B.F.1
Nelson, J.A.2
-
51
-
-
1942521014
-
Mismatch repair-mediated G2/M arrest by 6-thioguanine involves the ATR-Chkl pathway
-
Yamane K., Taylor K., Kinsella T.J. Mismatch repair-mediated G2/M arrest by 6-thioguanine involves the ATR-Chkl pathway. Biochem. Biophys. Res. Commun. 318:2004;297-302
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.318
, pp. 297-302
-
-
Yamane, K.1
Taylor, K.2
Kinsella, T.J.3
-
52
-
-
0036841293
-
Activation of Akt/protein kinase B overcomes a G(2)/M cell cycle checkpoint induced by DNA damage
-
Kandel E.S., Skeen J., Majewski N., Di Cristofano A., Pandolfi P.P., Feliciano C.S., Gartel A., Hay N. Activation of Akt/protein kinase B overcomes a G(2)/M cell cycle checkpoint induced by DNA damage. Mol. Cell Biol. 22:2002;7831-7841
-
(2002)
Mol. Cell Biol.
, vol.22
, pp. 7831-7841
-
-
Kandel, E.S.1
Skeen, J.2
Majewski, N.3
Di Cristofano, A.4
Pandolfi, P.P.5
Feliciano, C.S.6
Gartel, A.7
Hay, N.8
-
53
-
-
0033527577
-
Heregulin induces phosphorylation of BRCA1 through phosphatidylinositol 3-Kinase/AKT in breast cancer cells
-
Altiok S., Batt D., Altiok N., Papautsky A., Downward J., Roberts T.M., Avraham H. Heregulin induces phosphorylation of BRCA1 through phosphatidylinositol 3-Kinase/AKT in breast cancer cells. J. Biol. Chem. 274:1999;32274-32278
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 32274-32278
-
-
Altiok, S.1
Batt, D.2
Altiok, N.3
Papautsky, A.4
Downward, J.5
Roberts, T.M.6
Avraham, H.7
-
55
-
-
17944370512
-
Adenosine nucleotide modulates the physical interaction between hMSH2 and BRCA1
-
Wang Q., Zhang H., Guerrette S., Chen J., Mazurek A., Wilson T., Slupianek A., Skorski T., Fishel R., Greene M.I. Adenosine nucleotide modulates the physical interaction between hMSH2 and BRCA1. Oncogene. 20:2001;4640-4649
-
(2001)
Oncogene
, vol.20
, pp. 4640-4649
-
-
Wang, Q.1
Zhang, H.2
Guerrette, S.3
Chen, J.4
Mazurek, A.5
Wilson, T.6
Slupianek, A.7
Skorski, T.8
Fishel, R.9
Greene, M.I.10
-
56
-
-
0034655991
-
BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures
-
Wang Y., Cortez D., Yazdi P., Neff N., Elledge S.J., Qin J. BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. Genes Dev. 14:2000;927-939
-
(2000)
Genes Dev.
, vol.14
, pp. 927-939
-
-
Wang, Y.1
Cortez, D.2
Yazdi, P.3
Neff, N.4
Elledge, S.J.5
Qin, J.6
-
57
-
-
0033841622
-
Molecular mechanisms involved in cisplatin cytotoxicity
-
Jordan P., Carmo-Fonseca M. Molecular mechanisms involved in cisplatin cytotoxicity. Cell Mol. Life Sci. 57:2000;1229-1235
-
(2000)
Cell Mol. Life Sci.
, vol.57
, pp. 1229-1235
-
-
Jordan, P.1
Carmo-Fonseca, M.2
-
58
-
-
0035400494
-
Recognition of cisplatin adducts by cellular proteins
-
Kartalou M., Essigmann J.M. Recognition of cisplatin adducts by cellular proteins. Mutat. Res. 478:2001;1-21
-
(2001)
Mutat. Res.
, vol.478
, pp. 1-21
-
-
Kartalou, M.1
Essigmann, J.M.2
-
59
-
-
0029985445
-
Microsatellite instability, apoptosis, and loss of p53 function in drug-resistant tumor cells
-
Anthoney D.A., Mcllwrath A.J., Gallagher W.M., Edlin A.R., Brown R. Microsatellite instability, apoptosis, and loss of p53 function in drug-resistant tumor cells. Cancer Res. 56:1996;1374-1381
-
(1996)
Cancer Res.
, vol.56
, pp. 1374-1381
-
-
Anthoney, D.A.1
McLlwrath, A.J.2
Gallagher, W.M.3
Edlin, A.R.4
Brown, R.5
-
60
-
-
0031053575
-
Recognition and repair of compound DNA lesions (base damage and mismatch) by human mismatch repair and excision repair systems
-
Mu D., Tursun M., Duckett D.R., Drummond J.T., Modrich P., Sancar A. Recognition and repair of compound DNA lesions (base damage and mismatch) by human mismatch repair and excision repair systems. Mol. Cell Biol. 17:1997;760-769
-
(1997)
Mol. Cell Biol.
, vol.17
, pp. 760-769
-
-
Mu, D.1
Tursun, M.2
Duckett, D.R.3
Drummond, J.T.4
Modrich, P.5
Sancar, A.6
-
61
-
-
8944230189
-
Loss of DNA mismatch repair in acquired resistance to cisplatin
-
Aebi S., Kurdi-Haidar B., Gordon R., Cenni B., Zheng H., Fink D., Christen R.D., Boland C.R., Koi M., Fishel R., Howell S.B. Loss of DNA mismatch repair in acquired resistance to cisplatin. Cancer Res. 56:1996;3087-3090
-
(1996)
Cancer Res.
, vol.56
, pp. 3087-3090
-
-
Aebi, S.1
Kurdi-Haidar, B.2
Gordon, R.3
Cenni, B.4
Zheng, H.5
Fink, D.6
Christen, R.D.7
Boland, C.R.8
Koi, M.9
Fishel, R.10
Howell, S.B.11
-
62
-
-
0030811508
-
Selective recognition of a cisplatin-DNA adduct by human mismatch repair proteins
-
Yamada M., O'Regan E., Brown R., Karran P. Selective recognition of a cisplatin-DNA adduct by human mismatch repair proteins. Nucl. Acids Res. 25:1997;491-496
-
(1997)
Nucl. Acids Res.
, vol.25
, pp. 491-496
-
-
Yamada, M.1
O'Regan, E.2
Brown, R.3
Karran, P.4
-
63
-
-
0031908505
-
The effect of different chemotherapeutic agents on the enrichment of DNA mismatch repair-deficient tumour cells
-
Fink D., Nebel S., Norris P.S., Aebi S., Kim H.K., Haas M., Howell S.B. The effect of different chemotherapeutic agents on the enrichment of DNA mismatch repair-deficient tumour cells. Br. J. Cancer. 77:1998;703-708
-
(1998)
Br. J. Cancer
, vol.77
, pp. 703-708
-
-
Fink, D.1
Nebel, S.2
Norris, P.S.3
Aebi, S.4
Kim, H.K.5
Haas, M.6
Howell, S.B.7
-
64
-
-
0030877559
-
Differential induction of c-Jun NH2-terminal kinase and c-Abl kinase in DNA mismatch repair-proficient and -deficient cells exposed to cisplatin
-
Nehme A., Baskaran R., Aebi S., Fink D., Nebel S., Cenni B., Wang J.Y., Howell S.B., Christen R.D. Differential induction of c-Jun NH2-terminal kinase and c-Abl kinase in DNA mismatch repair-proficient and -deficient cells exposed to cisplatin. Cancer Res. 57:1997;3253-3257
-
(1997)
Cancer Res.
, vol.57
, pp. 3253-3257
-
-
Nehme, A.1
Baskaran, R.2
Aebi, S.3
Fink, D.4
Nebel, S.5
Cenni, B.6
Wang, J.Y.7
Howell, S.B.8
Christen, R.D.9
-
65
-
-
15444350120
-
In vitro and in vivo resistance to cisplatin in cells that have lost DNA mismatch repair
-
Fink D., Zheng H., Nebel S., Norris P.S., Aebi S., Lin T.P., Nehme A., Christen R.D., Haas M., MacLeod C.L., Howell S.B. In vitro and in vivo resistance to cisplatin in cells that have lost DNA mismatch repair. Cancer Res. 57:1997;1841-1845
-
(1997)
Cancer Res.
, vol.57
, pp. 1841-1845
-
-
Fink, D.1
Zheng, H.2
Nebel, S.3
Norris, P.S.4
Aebi, S.5
Lin, T.P.6
Nehme, A.7
Christen, R.D.8
Haas, M.9
MacLeod, C.L.10
Howell, S.B.11
-
66
-
-
0031855988
-
Enrichment for DNA mismatch repair-deficient cells during treatment with cisplatin
-
Fink D., Nebel S., Norris P.S., Baergen R.N., Wilczynski S.P., Costa M.J., Haas M., Cannistra S.A., Howell S.B. Enrichment for DNA mismatch repair-deficient cells during treatment with cisplatin. Int. J. Cancer. 77:1998;741-746
-
(1998)
Int. J. Cancer
, vol.77
, pp. 741-746
-
-
Fink, D.1
Nebel, S.2
Norris, P.S.3
Baergen, R.N.4
Wilczynski, S.P.5
Costa, M.J.6
Haas, M.7
Cannistra, S.A.8
Howell, S.B.9
-
67
-
-
0032529467
-
The role of hMLHl, hMSH3, and hMSH6 defects in cisplatin and oxaliplatin resistance: Correlation with replicative bypass of platinum-DNA adducts
-
Vaisman A., Varchenko M., Umar A., Kunkel T.A., Risinger J.I., Barrett J.C., Hamilton T.C., Chaney S.G. The role of hMLHl, hMSH3, and hMSH6 defects in cisplatin and oxaliplatin resistance: correlation with replicative bypass of platinum-DNA adducts. Cancer Res. 58:1998;3579-3585
-
(1998)
Cancer Res.
, vol.58
, pp. 3579-3585
-
-
Vaisman, A.1
Varchenko, M.2
Umar, A.3
Kunkel, T.A.4
Risinger, J.I.5
Barrett, J.C.6
Hamilton, T.C.7
Chaney, S.G.8
-
68
-
-
0033535612
-
A role for methylation of the hMLHl promoter in loss of hMLHl expression and drug resistance in ovarian cancer
-
Strathdee G., MacKean M.J., Illand M., Brown R. A role for methylation of the hMLHl promoter in loss of hMLHl expression and drug resistance in ovarian cancer. Oncogene. 18:1999;2335-2341
-
(1999)
Oncogene
, vol.18
, pp. 2335-2341
-
-
Strathdee, G.1
MacKean, M.J.2
Illand, M.3
Brown, R.4
-
69
-
-
0029812676
-
Cisplatin and adriamycin resistance are associated with MutLalpha and mismatch repair deficiency in an ovarian tumor cell line
-
Drummond J.T., Anthoney A., Brown R., Modrich P. Cisplatin and adriamycin resistance are associated with MutLalpha and mismatch repair deficiency in an ovarian tumor cell line. J. Biol. Chem. 271:1996;19645-19648
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 19645-19648
-
-
Drummond, J.T.1
Anthoney, A.2
Brown, R.3
Modrich, P.4
-
70
-
-
0033561772
-
Decreased cisplatin damage-dependent DNA synthesis in cellular extracts of mismatch repair deficient cells
-
Ferry K.V., Fink D., Johnson S.W., Nebel S., Hamilton T.C., Howell S.B. Decreased cisplatin damage-dependent DNA synthesis in cellular extracts of mismatch repair deficient cells. Biochem. Pharmacol. 57:1999;861-867
-
(1999)
Biochem. Pharmacol.
, vol.57
, pp. 861-867
-
-
Ferry, K.V.1
Fink, D.2
Johnson, S.W.3
Nebel, S.4
Hamilton, T.C.5
Howell, S.B.6
-
71
-
-
0033016378
-
Induction of JNK and c-Abl signalling by cisplatin and oxaliplatin in mismatch repair-proficient and -deficient cells
-
Nehme A., Baskaran R., Nebel S., Fink D., Howell S.B., Wang J.Y., Christen R.D. Induction of JNK and c-Abl signalling by cisplatin and oxaliplatin in mismatch repair-proficient and -deficient cells. Br. J. Cancer. 79:1999;1104-1110
-
(1999)
Br. J. Cancer
, vol.79
, pp. 1104-1110
-
-
Nehme, A.1
Baskaran, R.2
Nebel, S.3
Fink, D.4
Howell, S.B.5
Wang, J.Y.6
Christen, R.D.7
-
72
-
-
0030741503
-
HMLHl expression and cellular responses of ovarian tumour cells to treatment with cytotoxic anticancer agents
-
Brown R., Hirst G.L., Gallagher W.M., Mcllwrath A.J., Margison G.P., van, der, Zee, Ag D.A., Anthoney hMLHl expression and cellular responses of ovarian tumour cells to treatment with cytotoxic anticancer agents. Oncogene. 15:1997;45-52
-
(1997)
Oncogene
, vol.15
, pp. 45-52
-
-
Brown, R.1
Hirst, G.L.2
Gallagher, W.M.3
McLlwrath, A.J.4
Margison, G.P.5
Van6
Der7
Zee8
Ag, D.A.9
Anthoney10
-
73
-
-
0030819872
-
Resistance to cytotoxic drugs in DNA mismatch repair-deficient cells
-
Aebi S., Fink D., Gordon R., Kim H.K., Zheng H., Fink J.L., Howell S.B. Resistance to cytotoxic drugs in DNA mismatch repair-deficient cells. Clin. Cancer Res. 3:1997;1763-1767
-
(1997)
Clin. Cancer Res.
, vol.3
, pp. 1763-1767
-
-
Aebi, S.1
Fink, D.2
Gordon, R.3
Kim, H.K.4
Zheng, H.5
Fink, J.L.6
Howell, S.B.7
-
74
-
-
0345256652
-
Cisplatin: Mode of cytotoxic action and molecular basis of resistance
-
Siddik Z.H. Cisplatin: mode of cytotoxic action and molecular basis of resistance. Oncogene. 22:2003;7265-7279
-
(2003)
Oncogene
, vol.22
, pp. 7265-7279
-
-
Siddik, Z.H.1
-
75
-
-
0030751955
-
Differential human nucleotide excision repair of paired and mispaired cisplatin-DNA adducts
-
Moggs J.G., Szymkowski D.E., Yamada M., Karran P., Wood R.D. Differential human nucleotide excision repair of paired and mispaired cisplatin-DNA adducts. Nucl. Acids Res. 25:1997;480-491
-
(1997)
Nucl. Acids Res.
, vol.25
, pp. 480-491
-
-
Moggs, J.G.1
Szymkowski, D.E.2
Yamada, M.3
Karran, P.4
Wood, R.D.5
-
76
-
-
0034967556
-
ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chkl
-
Zhao H., Piwnica-Worms H. ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chkl. Mol. Cell Biol. 21:2001;4129-4139
-
(2001)
Mol. Cell Biol.
, vol.21
, pp. 4129-4139
-
-
Zhao, H.1
Piwnica-Worms, H.2
-
77
-
-
0035093544
-
Cisplatinum and taxol induce different patterns of p53 phosphorylation
-
Damia G., Filiberti L., Vikhanskaya F., Carrassa L., Taya Y., D'lncalci M., Broggini M. Cisplatinum and taxol induce different patterns of p53 phosphorylation. Neoplasia. 3:2001;10-16
-
(2001)
Neoplasia
, vol.3
, pp. 10-16
-
-
Damia, G.1
Filiberti, L.2
Vikhanskaya, F.3
Carrassa, L.4
Taya, Y.5
D'Lncalci, M.6
Broggini, M.7
-
78
-
-
0027936057
-
Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N′-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLHl mutation
-
[published erratum appears in Cancer Res. 55 (1995) 201]
-
M. Koi, A. Umar, D.P. Chauhan, S.P. Cherian, J.M. Carethers, T.A. Kunkel, C.R. Boland, Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N′-nitro-N- nitrosoguanidine tolerance in colon tumor cells with homozygous hMLHl mutation [published erratum appears in Cancer Res. 55 (1995) 201], Cancer Res. 54 (1994) 4308-4312.
-
(1994)
Cancer Res.
, vol.54
, pp. 4308-4312
-
-
Koi, M.1
Umar, A.2
Chauhan, D.P.3
Cherian, S.P.4
Carethers, J.M.5
Kunkel, T.A.6
Boland, C.R.7
-
79
-
-
0030776227
-
Correction of hypermutability, N-methyl-N′-nitro-N-nitrosoguanidine resistance, and defective DNA mismatch repair by introducing chromosome 2 into human tumor cells with mutations in MSH2 and MSH6
-
Umar A., Koi M., Risinger J.I., Glaab W.E., Tindall K.R., Kolodner R.D., Boland C.R., Barrett J.C., Kunkel T.A. Correction of hypermutability, N-methyl-N′-nitro-N-nitrosoguanidine resistance, and defective DNA mismatch repair by introducing chromosome 2 into human tumor cells with mutations in MSH2 and MSH6. Cancer Res. 57:1997;3949-3955
-
(1997)
Cancer Res.
, vol.57
, pp. 3949-3955
-
-
Umar, A.1
Koi, M.2
Risinger, J.I.3
Glaab, W.E.4
Tindall, K.R.5
Kolodner, R.D.6
Boland, C.R.7
Barrett, J.C.8
Kunkel, T.A.9
-
80
-
-
0037041027
-
DNA damage invokes mismatch repair-dependent cyclin D1 attenuation and retinoblastoma signaling pathways to inhibit CDK2
-
Lan Z., Sever-Chroneos Z., Strobeck M.W., Park C.H., Baskaran R., Edelmann W., Leone G., Knudsen E.S. DNA damage invokes mismatch repair-dependent cyclin D1 attenuation and retinoblastoma signaling pathways to inhibit CDK2. J. Biol. Chem. 277:2002;8372-8381
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 8372-8381
-
-
Lan, Z.1
Sever-Chroneos, Z.2
Strobeck, M.W.3
Park, C.H.4
Baskaran, R.5
Edelmann, W.6
Leone, G.7
Knudsen, E.S.8
-
81
-
-
0033600234
-
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
-
Gong J.G., Costanzo A., Yang H.Q., Melino G., Kaelin W.G. Jr., Levrero M., Wang J.Y. The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage. Nature. 399:1999;806-809
-
(1999)
Nature
, vol.399
, pp. 806-809
-
-
Gong, J.G.1
Costanzo, A.2
Yang, H.Q.3
Melino, G.4
Kaelin Jr., W.G.5
Levrero, M.6
Wang, J.Y.7
-
82
-
-
0344284564
-
Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin
-
Shimodaira H., Yoshioka-Yamashita A., Kolodner R.D., Wang J.Y. Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin. Proc. Natl. Acad. Sci. U.S.A. 100:2003;2420-2425
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 2420-2425
-
-
Shimodaira, H.1
Yoshioka-Yamashita, A.2
Kolodner, R.D.3
Wang, J.Y.4
-
83
-
-
15444348851
-
Role of DNA mismatch repair in the cytotoxicity of ionizing radiation
-
Fritzell J.A., Narayanan L., Baker S.M., Bronner C.E., Andrew S.E., Prolla T.A., Bradley A., Jirik F.R., Liskay R.M., Glazer P.M. Role of DNA mismatch repair in the cytotoxicity of ionizing radiation. Cancer Res. 57:1997;5143-5147
-
(1997)
Cancer Res.
, vol.57
, pp. 5143-5147
-
-
Fritzell, J.A.1
Narayanan, L.2
Baker, S.M.3
Bronner, C.E.4
Andrew, S.E.5
Prolla, T.A.6
Bradley, A.7
Jirik, F.R.8
Liskay, R.M.9
Glazer, P.M.10
-
84
-
-
0032578544
-
Mouse embryonic stem cells carrying one or two defective Msh2 alleles respond abnormally to oxidative stress inflicted by low-level radiation
-
DeWeese T.L., Shipman J.M., Larrier N.A., Buckley N.M., Kidd L.R., Groopman J.D., Cutler R.G., te Riele H., Nelson W.G. Mouse embryonic stem cells carrying one or two defective Msh2 alleles respond abnormally to oxidative stress inflicted by low-level radiation. Proc. Natl. Acad. Sci. U.S.A. 95:1998;11915-11920
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 11915-11920
-
-
Deweese, T.L.1
Shipman, J.M.2
Larrier, N.A.3
Buckley, N.M.4
Kidd, L.R.5
Groopman, J.D.6
Cutler, R.G.7
Te Riele, H.8
Nelson, W.G.9
-
85
-
-
0033402721
-
Mismatch repair, G(2)/M cell cycle arrest and lethality after DNA damage
-
Aquilina G., Crescenzi M., Bignami M. Mismatch repair, G(2)/M cell cycle arrest and lethality after DNA damage. Carcinogenesis. 20:1999;2317-2326
-
(1999)
Carcinogenesis
, vol.20
, pp. 2317-2326
-
-
Aquilina, G.1
Crescenzi, M.2
Bignami, M.3
-
86
-
-
0035890422
-
Loss of DNA mismatch repair imparts defective cdc2 signaling and G(2) arrest responses without altering survival after ionizing radiation
-
Yan T., Schupp J.E., Hwang H.S., Wagner M.W., Berry S.E., Strickfaden S., Veigl M.L., Sedwick W.D., Boothman D.A., Kinsella T.J. Loss of DNA mismatch repair imparts defective cdc2 signaling and G(2) arrest responses without altering survival after ionizing radiation. Cancer Res. 61:2001;8290-8297
-
(2001)
Cancer Res.
, vol.61
, pp. 8290-8297
-
-
Yan, T.1
Schupp, J.E.2
Hwang, H.S.3
Wagner, M.W.4
Berry, S.E.5
Strickfaden, S.6
Veigl, M.L.7
Sedwick, W.D.8
Boothman, D.A.9
Kinsella, T.J.10
-
87
-
-
0038297562
-
The mammalian mismatch repair protein MSH2 is required for correct MRE11 and RAD51 relocalization and for efficient cell cycle arrest induced by ionizing radiation in G2 phase
-
Franchitto A., Pichierri P., Piergentili R., Crescenzi M., Bignami M., Palitti F. The mammalian mismatch repair protein MSH2 is required for correct MRE11 and RAD51 relocalization and for efficient cell cycle arrest induced by ionizing radiation in G2 phase. Oncogene. 22:2003;2110-2120
-
(2003)
Oncogene
, vol.22
, pp. 2110-2120
-
-
Franchitto, A.1
Pichierri, P.2
Piergentili, R.3
Crescenzi, M.4
Bignami, M.5
Palitti, F.6
-
88
-
-
0035882531
-
Resistance to topoisomerase poisons due to loss of DNA mismatch repair
-
Fedier A., Schwarz V.A., Walt H., Carpini R.D., Haller U., Fink D. Resistance to topoisomerase poisons due to loss of DNA mismatch repair. Int. J. Cancer. 93:2001;571-576
-
(2001)
Int. J. Cancer
, vol.93
, pp. 571-576
-
-
Fedier, A.1
Schwarz, V.A.2
Walt, H.3
Carpini, R.D.4
Haller, U.5
Fink, D.6
-
89
-
-
0035418619
-
The role of the DNA mismatch repair system in the cytotoxicity of the topoisomerase inhibitors camptothecin and etoposide to human colorectal cancer cells
-
Jacob S., Aguado M., Fallik D., Praz F. The role of the DNA mismatch repair system in the cytotoxicity of the topoisomerase inhibitors camptothecin and etoposide to human colorectal cancer cells. Cancer Res. 61:2001;6555-6562
-
(2001)
Cancer Res.
, vol.61
, pp. 6555-6562
-
-
Jacob, S.1
Aguado, M.2
Fallik, D.3
Praz, F.4
-
90
-
-
0031975303
-
N-(2-chloroethyl)-N′-cyclohexyl-N-nitrosourea sensitivity in mismatch repair-defective human cells
-
Aquilina G., Ceccotti S., Martinelli S., Hampson R., Bignami M. N-(2-chloroethyl)-N′-cyclohexyl-N-nitrosourea sensitivity in mismatch repair-defective human cells. Cancer Res. 58:1998;135-141
-
(1998)
Cancer Res.
, vol.58
, pp. 135-141
-
-
Aquilina, G.1
Ceccotti, S.2
Martinelli, S.3
Hampson, R.4
Bignami, M.5
-
91
-
-
0033969484
-
Mismatch repair and p53 independently affect sensitivity to N-(2-chloroethyl)-N′-cyclohexyl-N-nitrosourea
-
Aquilina G., Ceccotti S., Martinelli S., Soddu S., Crescenzi M., Branch P., Karran P., Bignami M. Mismatch repair and p53 independently affect sensitivity to N-(2-chloroethyl)-N′-cyclohexyl-N-nitrosourea. Clin. Cancer Res. 6:2000;671-680
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 671-680
-
-
Aquilina, G.1
Ceccotti, S.2
Martinelli, S.3
Soddu, S.4
Crescenzi, M.5
Branch, P.6
Karran, P.7
Bignami, M.8
-
92
-
-
0029887819
-
Transcription-coupled repair deficiency and mutations in human mismatch repair genes
-
Mellon I., Rajpal D.K., Koi M., Boland C.R., Champe G.N. Transcription-coupled repair deficiency and mutations in human mismatch repair genes. Science. 272:1996;557-560
-
(1996)
Science
, vol.272
, pp. 557-560
-
-
Mellon, I.1
Rajpal, D.K.2
Koi, M.3
Boland, C.R.4
Champe, G.N.5
-
93
-
-
0030777110
-
Differential involvement of the human mismatch repair proteins, hMLHl and hMSH2, in transcription-coupled repair
-
Leadon S.A., Avrutskaya A.V. Differential involvement of the human mismatch repair proteins, hMLHl and hMSH2, in transcription-coupled repair. Cancer Res. 57:1997;3784-3791
-
(1997)
Cancer Res.
, vol.57
, pp. 3784-3791
-
-
Leadon, S.A.1
Avrutskaya, A.V.2
-
94
-
-
0031746495
-
Requirement for DNA mismatch repairproteins in the transcription- coupled repair of thymine glycols in Saccharomyces cerevisiae
-
Leadon S.A., Avrutskaya A.V. Requirement for DNA mismatch repairproteins in the transcription- coupled repair of thymine glycols in Saccharomyces cerevisiae. Mutat. Res. 407:1998;177-187
-
(1998)
Mutat. Res.
, vol.407
, pp. 177-187
-
-
Leadon, S.A.1
Avrutskaya, A.V.2
-
95
-
-
0035945640
-
Mouse mismatch repair gene Msh2 is not essential for transcription- coupled repair of UV-induced cyclobutane pyrimidine dimers
-
Sonneveld E., Vrieling H., Mullenders L.H., van A., Hoffen Mouse mismatch repair gene Msh2 is not essential for transcription-coupled repair of UV-induced cyclobutane pyrimidine dimers. Oncogene. 20:2001;538-541
-
(2001)
Oncogene
, vol.20
, pp. 538-541
-
-
Sonneveld, E.1
Vrieling, H.2
Mullenders, L.H.3
Van, A.4
Hoffen5
-
96
-
-
0037226473
-
The mismatch repair system is required for S-phase checkpoint activation
-
Brown K.D., Rathi A., Kamath R., Beardsley D.I., Zhan Q., Mannino J.L., Baskaran R. The mismatch repair system is required for S-phase checkpoint activation. Nat. Genet. 33:2003;80-84
-
(2003)
Nat. Genet.
, vol.33
, pp. 80-84
-
-
Brown, K.D.1
Rathi, A.2
Kamath, R.3
Beardsley, D.I.4
Zhan, Q.5
Mannino, J.L.6
Baskaran, R.7
-
97
-
-
2442706833
-
Dependence of the cytotoxicity of DNA damaging agents on the mismatch repair status of human cells
-
Papouli E., Cejka P., Jiricny J. Dependence of the cytotoxicity of DNA damaging agents on the mismatch repair status of human cells. Cancer Res. 64:2004;3391-3394
-
(2004)
Cancer Res.
, vol.64
, pp. 3391-3394
-
-
Papouli, E.1
Cejka, P.2
Jiricny, J.3
-
98
-
-
2442560576
-
Is mismatch repair really required for ionizing radiation-induced DNA damage signaling?
-
Cejka P., Stojic L., Marra G., Jiricny J. Is mismatch repair really required for ionizing radiation-induced DNA damage signaling? Nat. Genet. 36:2004;432-433
-
(2004)
Nat. Genet.
, vol.36
, pp. 432-433
-
-
Cejka, P.1
Stojic, L.2
Marra, G.3
Jiricny, J.4
-
99
-
-
0031848832
-
Involvement of the mismatch repair system in temozolomide-induced apoptosis
-
D'Atri S., Tentori L., Lacal P.M., Graziani G., Pagani E., Benincasa E., Zambruno G., Bonmassar E., Jiricny J. Involvement of the mismatch repair system in temozolomide-induced apoptosis. Mol. Pharmacol. 54:1998;334-341
-
(1998)
Mol. Pharmacol.
, vol.54
, pp. 334-341
-
-
D'Atri, S.1
Tentori, L.2
Lacal, P.M.3
Graziani, G.4
Pagani, E.5
Benincasa, E.6
Zambruno, G.7
Bonmassar, E.8
Jiricny, J.9
-
100
-
-
0033607055
-
HMutSalpha- and hMutLalpha-dependent phosphorylation of p53 in response to DNA methylator damage
-
Duckett D.R., Bronstein S.M., Taya Y., Modrich P. hMutSalpha- and hMutLalpha-dependent phosphorylation of p53 in response to DNA methylator damage. Proc. Natl. Acad. Sci. U.S.A. 96:1999;12384-12388
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 12384-12388
-
-
Duckett, D.R.1
Bronstein, S.M.2
Taya, Y.3
Modrich, P.4
-
101
-
-
0032851842
-
Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents
-
Hickman M.J., Samson L.D. Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents. Proc. Natl. Acad. Sci. U.S.A. 96:1999;10764-10769
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 10764-10769
-
-
Hickman, M.J.1
Samson, L.D.2
-
102
-
-
3042544915
-
Proteolysis of the mismatch repair protein MLH1 by caspase-3 promotes DNA damage-induced apoptosis
-
Chen F., Arseven O.K., Cryns V.L. Proteolysis of the mismatch repair protein MLH1 by caspase-3 promotes DNA damage-induced apoptosis. J. Biol. Chem. 279:2004;27542-27548
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 27542-27548
-
-
Chen, F.1
Arseven, O.K.2
Cryns, V.L.3
-
103
-
-
1842715589
-
Apoptotic signaling in response to a single type of DNA lesion, O(6)-methylguanine
-
Hickman M.J., Samson L.D. Apoptotic signaling in response to a single type of DNA lesion, O(6)-methylguanine. Mol. Cell. 14:2004;105-116
-
(2004)
Mol. Cell
, vol.14
, pp. 105-116
-
-
Hickman, M.J.1
Samson, L.D.2
-
104
-
-
0347626103
-
Mismatch repair-dependent transcriptome changes in human cells treated with the methylating agent N-methyl-n′-nitro-N-mtrosoguanidine
-
Di Pietro M., Marra G., Cejka P., Stojic L., Menigatti M., Cattaruzza M.S., Jiricny J. Mismatch repair-dependent transcriptome changes in human cells treated with the methylating agent N-methyl-n′-nitro-N-mtrosoguanidine. Cancer Res. 63:2003;8158-8166
-
(2003)
Cancer Res.
, vol.63
, pp. 8158-8166
-
-
Di Pietro, M.1
Marra, G.2
Cejka, P.3
Stojic, L.4
Menigatti, M.5
Cattaruzza, M.S.6
Jiricny, J.7
-
105
-
-
0035866361
-
P53 modulates the effect of loss of DNA mismatch repair on the sensitivity of human colon cancer cells to the cytotoxic and mutagenic effects of cisplatin
-
Lin X., Ramamurthi K., Mishima M., Kondo A., Christen R.D., Howell S.B. P53 modulates the effect of loss of DNA mismatch repair on the sensitivity of human colon cancer cells to the cytotoxic and mutagenic effects of cisplatin. Cancer Res. 61:2001;1508-1516
-
(2001)
Cancer Res.
, vol.61
, pp. 1508-1516
-
-
Lin, X.1
Ramamurthi, K.2
Mishima, M.3
Kondo, A.4
Christen, R.D.5
Howell, S.B.6
-
106
-
-
0041928171
-
Potential role of MLH1 in the induction of p53 and apoptosis by blocking transcription on damaged DNA templates
-
Yanamadala S., Ljungman M. Potential role of MLH1 in the induction of p53 and apoptosis by blocking transcription on damaged DNA templates. Mol. Cancer Res. 1:2003;747-754
-
(2003)
Mol. Cancer Res.
, vol.1
, pp. 747-754
-
-
Yanamadala, S.1
Ljungman, M.2
-
107
-
-
0035866372
-
Involvement of mammalian MLH1 in the apoptotic response to peroxide-induced oxidative stress
-
Hardman R.A., Afshari C.A., Barrett J.C. Involvement of mammalian MLH1 in the apoptotic response to peroxide-induced oxidative stress. Cancer Res. 61:2001;1392-1397
-
(2001)
Cancer Res.
, vol.61
, pp. 1392-1397
-
-
Hardman, R.A.1
Afshari, C.A.2
Barrett, J.C.3
-
108
-
-
0031792779
-
Identification and characterization of a family of mammalian methyl-CpG binding proteins
-
Hendrich B., Bird A. Identification and characterization of a family of mammalian methyl-CpG binding proteins. Mol. Cell Biol. 18:1998;6538-6547
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 6538-6547
-
-
Hendrich, B.1
Bird, A.2
-
109
-
-
0033575886
-
The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites
-
Hendrich B., Hardeland U., Ng H.H., Jiricny J., Bird A. The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites. Nature. 401:1999;301-304
-
(1999)
Nature
, vol.401
, pp. 301-304
-
-
Hendrich, B.1
Hardeland, U.2
Ng, H.H.3
Jiricny, J.4
Bird, A.5
-
110
-
-
0033616583
-
MED1, a novel human methyl-CpG-binding endonuclease, interacts with DNA mismatch repair protein MLH1
-
Bellacosa A., Cicchillitti L., Schepis F., Riccio A., Yeung A.T., Matsumoto Y., Golemis E.A., Genuardi M., Neri G. MED1, a novel human methyl-CpG-binding endonuclease, interacts with DNA mismatch repair protein MLH1. Proc. Natl. Acad. Sci. U.S.A. 96:1999;3969-3974
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 3969-3974
-
-
Bellacosa, A.1
Cicchillitti, L.2
Schepis, F.3
Riccio, A.4
Yeung, A.T.5
Matsumoto, Y.6
Golemis, E.A.7
Genuardi, M.8
Neri, G.9
-
111
-
-
7044278257
-
The base excision repair enzyme MED1 mediates DNA damage response to antitumor drugs and is associated with mismatch repair system integrity
-
Cortellino S., Turner D., Masciullo V., Schepis F., Albino D., Daniel R., Skalka A.M., Meropol N.J., Alberti C., Lame L., Bellacosa A. The base excision repair enzyme MED1 mediates DNA damage response to antitumor drugs and is associated with mismatch repair system integrity. Proc. Natl. Acad. Sci. U.S.A. 100:2003;15071-15076
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 15071-15076
-
-
Cortellino, S.1
Turner, D.2
Masciullo, V.3
Schepis, F.4
Albino, D.5
Daniel, R.6
Skalka, A.M.7
Meropol, N.J.8
Alberti, C.9
Lame, L.10
Bellacosa, A.11
-
112
-
-
0042790463
-
MBD4 deficiency reduces the apoptotic response to DNA-damaging agents in the murine small intestine
-
Sansom O.J., Zabkiewicz J., Bishop S.M., Guy J., Bird A., Clarke A.R. MBD4 deficiency reduces the apoptotic response to DNA-damaging agents in the murine small intestine. Oncogene. 22:2003;7130-7136
-
(2003)
Oncogene
, vol.22
, pp. 7130-7136
-
-
Sansom, O.J.1
Zabkiewicz, J.2
Bishop, S.M.3
Guy, J.4
Bird, A.5
Clarke, A.R.6
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