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Volumn 3, Issue 5, 2002, Pages 364-375

The 3′-5′ exonucleases

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA POLYMERASE; EXONUCLEASE; MRE11 PROTEIN; PROTEIN; PROTEIN APE1; PROTEIN P53; PROTEIN RAD1; PROTEIN RAD9; PROTEIN TREX1; PROTEIN TREX2; PROTEIN VDJP; UNCLASSIFIED DRUG; WRN HELICASE; DNA DIRECTED DNA POLYMERASE GAMMA; EXODEOXYRIBONUCLEASE; EXODEOXYRIBONUCLEASE V; HELICASE; PHOSPHOPROTEIN; RECQ HELICASE; THREE PRIME REPAIR EXONUCLEASE 1; TREX1 PROTEIN, HUMAN; WRN PROTEIN, HUMAN;

EID: 0036016447     PISSN: 14710072     EISSN: None     Source Type: Journal    
DOI: 10.1038/nrm804     Document Type: Review
Times cited : (225)

References (105)
  • 1
    • 0031984807 scopus 로고    scopus 로고
    • Highly sensitive apurlnic/apydmidinic site assay can detect spontaneous and chemical induced depurination under physiological conditions
    • (1998) Cancer Res. , vol.58 , pp. 222-225
    • Nakamura, J.1
  • 2
    • 0027278557 scopus 로고
    • Instability and decay of the primary structure of DNA
    • (1993) Nature , vol.362 , pp. 709-715
    • Lindahl, T.1
  • 7
    • 0034958108 scopus 로고    scopus 로고
    • Defective DNA polymerase-δ proofreading causes cancer susceptibility in mice
    • (2001) Nature Med. , vol.7 , pp. 638-639
    • Goldsby, R.E.1
  • 16
    • 0033538461 scopus 로고    scopus 로고
    • Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3′-5′ exonucleases
    • (1999) J. Biol. Chem. , vol.274 , pp. 19655-19660
    • Mazur, D.J.1    Perrino, F.W.2
  • 18
    • 0031686571 scopus 로고    scopus 로고
    • The premature ageing syndrome protein, WRN, is a 3′→5′ exonuclease
    • (1998) Nature Genet. , vol.20 , pp. 114-116
    • Huang, S.1
  • 19
  • 24
    • 0033543559 scopus 로고    scopus 로고
    • Processive proofreading and the spatial relationship between polymerase and exonuclease active sites of bacteriophage φ29 DNA polymerase
    • (1999) J. Mol. Biol. , vol.292 , pp. 39-51
    • DeVega, M.1    Blanco, L.2    Salas, M.3
  • 25
    • 0024395470 scopus 로고
    • How DNA travels between the separate polymerase and 3′-5′ exonuclease sites of DNA polymerase I (Klenow fragment)
    • (1989) J. Biol. Chem. , vol.264 , pp. 10858-10866
    • Joyce, C.M.1
  • 27
    • 0025315748 scopus 로고
    • Hydrolysis of 3′-terminal mispairs in vitro by the 3′-5′ exonuclease of DNA polymerase δ permits subsequent extension by DNA polymerase α
    • (1990) Biochemistry , vol.29 , pp. 5226-5231
    • Perrino, F.W.1    Loeb, L.A.2
  • 32
    • 0029906624 scopus 로고    scopus 로고
    • Proliferating cell nuclear antigen promotes misincorporation catalyzed by calf thymus DNA polymerase δ
    • (1996) J. Biol. Chem. , vol.271 , pp. 31711-31717
    • Mozzherin, D.J.1
  • 33
    • 0024552845 scopus 로고
    • Differential extension of 3′ mispairs is a major contribution to the high fidelity of calf thymus DNA polymerase α
    • (1989) J. Biol. Chem. , vol.264 , pp. 2898-2905
    • Perrino, F.W.1    Loeb, L.A.2
  • 37
    • 0034595502 scopus 로고    scopus 로고
    • Evidence from mutational specificity studies yeast DNA polymerases δ and ε replicate different DNA strands at an intracellular replication fork
    • (2000) J. Mol. Biol. , vol.299 , pp. 405-419
    • Karthikeyan, R.1
  • 38
    • 0032588388 scopus 로고    scopus 로고
    • The 3′→5′ exonucleases of DNA polymerases δ and ε and the 5′-3′ exonuclease Exo 1 have major roles in postreplication mutation avoidance in Saccharomyces cerevisiae
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 2000-2007
    • Tran, H.T.1    Gordenin, D.A.2    Resnick, M.A.3
  • 40
    • 0025773554 scopus 로고
    • Mutator phenotype may be required for multistage carcinogenesis
    • (1991) Cancer Res. , vol.51 , pp. 3075-3079
    • Loeb, L.A.1
  • 47
    • 0026328236 scopus 로고
    • Fidelity of mammalian DNA replication and replicative DNA polymerases
    • (1991) Biochemistry , vol.30 , pp. 11751-11759
    • Thomas, D.C.1
  • 49
    • 0031104841 scopus 로고    scopus 로고
    • The FEN-1 family of structure-specific nucleases in eukaryotic DNA replication, recombination and repair
    • (1997) Bioessays , vol.19 , pp. 233-240
    • Ueber, M.R.1
  • 51
    • 0037786682 scopus 로고    scopus 로고
    • A human DNA editing enzyme homologous to the Escherichia coli DnaQ/MutD protein
    • (1999) EMBO J. , vol.18 , pp. 3868-3875
    • Höss, M.1
  • 53
    • 0034953044 scopus 로고    scopus 로고
    • Werner syndrome: Genetic and molecular basis of a premature ageing disorder
    • (2001) Cell Mol. Life Sci. , vol.58 , pp. 857-867
    • Lebel, M.1
  • 55
    • 0035971076 scopus 로고    scopus 로고
    • Requirements for the nucleolytic processing of DNA ends by the Werner syndrome protein-Ku70/80 complex
    • (2001) J. Biol. Chem. , vol.276 , pp. 9896-9902
    • Li, B.1    Comai, L.2
  • 59
  • 60
    • 17544402913 scopus 로고    scopus 로고
    • Mutations in the WRN gene in mice accelerate mortality in a p53-null background
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 3286-3291
    • Lombard, D.B.1
  • 62
    • 0027521657 scopus 로고
    • Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice
    • (1993) Nature Genet. , vol.5 , pp. 225-229
    • Harvey, M.1
  • 63
    • 0032560817 scopus 로고    scopus 로고
    • Excision of mismatched nucleotides from DNA: A potential mechanism for enhancing DNA replication fidlelity by the wild-type p53 protein
    • (1998) Oncogene , vol.17 , pp. 261-270
    • Huang, P.1
  • 64
    • 0033019052 scopus 로고    scopus 로고
    • Different regulation of the p53 core domain activities 3′-5′ exonuclease and sequence-specific DNA binding
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 2155-2168
    • Janus, F.1
  • 65
    • 0030826733 scopus 로고    scopus 로고
    • Induced N- and C-terminal cleavage of p53: A core fragment of p53, generated by interaction with damaged DNA, promotes cleavage of the N-terminus of full-length p53, whereas ssDNA induces C-terminal cleavage of p53
    • (1997) EMBO J. , vol.16 , pp. 6008-6017
    • Okorokov, A.L.1    Ponehel, F.2    Milner, J.3
  • 69
    • 0030814494 scopus 로고    scopus 로고
    • Female embryonic lethality in mice nullizygous for both Msh2 and p53
    • (1997) Nature Genet. , vol.17 , pp. 114-118
    • Cranston, A.1
  • 70
    • 0032860479 scopus 로고    scopus 로고
    • Cross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants
    • (1999) Nature Genet. , vol.23 , pp. 81-85
    • Chen, C.1    Kolodner, R.D.2
  • 72
    • 0033534613 scopus 로고    scopus 로고
    • Human homologs of Schizosaccharomyces pombe Rad1, Hus1 and Rad9 form a DNA damage-responsive protein complex
    • (1999) J. Biol. Chem. , vol.274 , pp. 567-570
    • Volkmer, E.1    Kamitz, I.M.2
  • 73
    • 0029143992 scopus 로고
    • Evidence for aconnection between the mismatch repair system and G2 cell cycle checkpoint
    • (1995) Cancer Res. , vol.55 , pp. 3721-3725
    • Hawn, M.T.1
  • 74
    • 0032540926 scopus 로고    scopus 로고
    • A human homologue of the Schizosaccharomyces pombe rad1* checkpoint gene encodes an exonuclease
    • (1998) J. Biol. Chem. , vol.273 , pp. 18332-18339
    • Parker, A.E.1
  • 79
    • 0025936119 scopus 로고
    • Isolation of cDNA clones encoding a human apurinic/apydmidinic endonuclease that corrects DNA repair and mutagenesis defects in Escherichia coli xth (exonuclease III) mutants
    • (1991) Nucleic Acids Res. , vol.19 , pp. 1087-1092
    • Robson, C.N.1    Hickson, I.D.2
  • 80
    • 0031720426 scopus 로고    scopus 로고
    • A murine AP-endonuclease genetargeted deficiency with post-implantation embryonic progression and ionizing sensitivity
    • (1998) Mutat. Res. , vol.409 , pp. 17-29
    • Ludwig, D.L.1
  • 82
    • 0037034035 scopus 로고    scopus 로고
    • An exonucleolytic activity of human apurinic/apyrimidinic endonuclease on 3′ mispaired DNA
    • (2002) Nature , vol.415 , pp. 655-659
    • Chou, K.M.1    Cheng, Y.C.2
  • 86
    • 0030031091 scopus 로고    scopus 로고
    • Large subunit of replication factor C (Rfc 1p/Cdc44p) is required for DNA replication and DNA repair in Saccharomyces cerevisiae
    • (1996) Genetics , vol.142 , pp. 65-78
    • McAlear, M.A.1    Tuffo, K.M.2    Holm, C.3
  • 88
    • 0015499986 scopus 로고
    • Deoxyribonucleic acid polymerase: Two distinct enzymes in one polypeptide. II. A proteolytic fragment containing the 5′ leads to 3′ exonucleas function. Restoration of intact enzyme function from the two proteolytic fragments
    • (1972) J. Biol. Chem. , vol.247 , pp. 232-240
    • Setlow, P.1    Kornberg, A.2
  • 90
    • 0014010871 scopus 로고
    • Separation and characterization of deoxyribonuclease of Escharichia coli B. Chromatographic separation and properties of two decxyribo-ollgonucleotidases
    • (1966) J. Biol. Chem. , vol.241 , pp. 3090-3896
    • Jorgensen, S.E.1    Koerner, J.F.2
  • 92
    • 0015499898 scopus 로고
    • Deoxynbonucleic acid polymerase: Two distinct enzymes in one polypeptide. I. A preteolylic fragment containing the polymerase and 3′ leads to 5′ exonuclease functions
    • (1972) J. Biol. Chem. , vol.247 , pp. 224-231
    • Setlow, P.1    Brutlag, D.2    Kornberg, A.3
  • 94
    • 0030887046 scopus 로고    scopus 로고
    • The Escherichia coli polB focus is identical to dinA, the structural gene for DNA polymerase II. Characterization of Pol II purified from polB mutant
    • (1997) J. Biol. Chem. , vol.272 , pp. 8611-8617
    • Qiu, Z.1    Goodman, M.F.2
  • 97
  • 99
    • 0030587492 scopus 로고    scopus 로고
    • Cloning and characterization of the human mitochondrial DNA polymerase, DNA polymerase γ
    • (1996) Genomics , vol.36 , pp. 449-458
    • Ropp, P.A.1    Copeland, W.C.2
  • 100
    • 0030604728 scopus 로고    scopus 로고
    • p53 protein exhibits 3′-to-5′ exonuclease activity
    • (1996) Cell , vol.85 , pp. 1089-1099
    • Mummenbrauer, T.1
  • 101
    • 0028174896 scopus 로고
    • The 3′ to 5′ exonucleases of both DNA polymerase δ and ε participate in correcting errors of DNA replication in Saccharomyces cerevisiae
    • (1994) Mol. Gen. Genet. , vol.242 , pp. 289-296
    • Morrison, A.1    Suglno, A.2
  • 102
    • 0033544724 scopus 로고    scopus 로고
    • The DNA double-strand break repair gene hMre 11 is mutated in individuals with an ataxiatelangiectasia-like disorder
    • (1999) Cell , vol.99 , pp. 577-587
    • Stewart, G.S.1
  • 103
    • 0032076248 scopus 로고    scopus 로고
    • The hMre 11/hRad50 protein complex and Nijmegen breakage syndrome: Linkage of double-strand break repair to the cellular DNA damage response
    • (1998) Cell , vol.93 , pp. 477-486
    • Carney, J.P.1
  • 105
    • 0032692565 scopus 로고    scopus 로고
    • Building a replisome from interacting pieces: Sliding clamp complexed to a peptide from DNA polymerase and a polymerase editing complex
    • (1999) Cell , vol.99 , pp. 155-166
    • Shamoo, Y.1    Steitz, T.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.