The kinetic and chemical mechanism of high-fidelity DNA polymerases

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1804, Issue 5, 2010, Pages 1041-1048

  Johnson, Kenneth A ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Conformational change; DNA polymerase; Enzyme dynamics; Fluorescence; Kinetics; Mechanism; Quench flow; Stopped flow; Transient

Indexed keywords

DNA POLYMERASE; EXONUCLEASE; METAL ION; PHOSPHOROTHIOIC ACID; PYROPHOSPHATE;

CATALYSIS; CONFORMATIONAL TRANSITION; DNA REPLICATION; DNA STRUCTURE; FLUORESCENCE; HYDROGEN BOND; KINETICS; NUCLEOTIDE BINDING SITE; POLYMERIZATION; PRIORITY JOURNAL; REVIEW; THERMODYNAMICS;

ANIMALS; CODON; DNA; DNA-DIRECTED DNA POLYMERASE; HUMANS; KINETICS;

EID: 77949570420     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2010.01.006     Document Type: Review

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