-
1
-
-
66149094205
-
Death receptor 5 internalization is required for lysosomal permeabilization by TRAIL in malignant liver cell lines
-
2365-2376 e2361-2367
-
Akazawa Y., Mott J.L., Bronk S.F., Werneburg N.W., Kahraman A., Guicciardi M.E., Meng X.W., Kohno S., Shah V.H., Kaufmann S.H., McNiven M.A., Gores G.J. Death receptor 5 internalization is required for lysosomal permeabilization by TRAIL in malignant liver cell lines. Gastroenterology 2009, 136. 2365-2376 e2361-2367.
-
(2009)
Gastroenterology
, vol.136
-
-
Akazawa, Y.1
Mott, J.L.2
Bronk, S.F.3
Werneburg, N.W.4
Kahraman, A.5
Guicciardi, M.E.6
Meng, X.W.7
Kohno, S.8
Shah, V.H.9
Kaufmann, S.H.10
McNiven, M.A.11
Gores, G.J.12
-
3
-
-
0031005956
-
Ceramide induces hepatocyte cell death through disruption of mitochondrial function in the rat
-
Arora A.S., Jones B.J., Patel T.C., Bronk S.F., Gores G.J. Ceramide induces hepatocyte cell death through disruption of mitochondrial function in the rat. Hepatology 1997, 25:958-963.
-
(1997)
Hepatology
, vol.25
, pp. 958-963
-
-
Arora, A.S.1
Jones, B.J.2
Patel, T.C.3
Bronk, S.F.4
Gores, G.J.5
-
4
-
-
33745727023
-
Apoptotic interactions of cytochrome c: redox flirting with anionic phospholipids within and outside of mitochondria
-
Bayir H., Fadeel B., Palladino M.J., Witasp E., Kurnikov I.V., Tyurina Y.Y., Tyurin V.A., Amoscato A.A., Jiang J., Kochanek P.M., DeKosky S.T., Greenberger J.S., Shvedova A.A., Kagan V.E. Apoptotic interactions of cytochrome c: redox flirting with anionic phospholipids within and outside of mitochondria. Biochim. Biophys. Acta 2006, 1757:648-659.
-
(2006)
Biochim. Biophys. Acta
, vol.1757
, pp. 648-659
-
-
Bayir, H.1
Fadeel, B.2
Palladino, M.J.3
Witasp, E.4
Kurnikov, I.V.5
Tyurina, Y.Y.6
Tyurin, V.A.7
Amoscato, A.A.8
Jiang, J.9
Kochanek, P.M.10
DeKosky, S.T.11
Greenberger, J.S.12
Shvedova, A.A.13
Kagan, V.E.14
-
5
-
-
34247849157
-
Cathepsin-cleaved BID promotes apoptosis in human neutrophils via oxidative stress-induced lysosomal membrane permeabilization
-
Blomgran R., Zheng L., Stendahl O. Cathepsin-cleaved BID promotes apoptosis in human neutrophils via oxidative stress-induced lysosomal membrane permeabilization. J. Leukoc. Biol. 2007, 81:1213-1223.
-
(2007)
J. Leukoc. Biol.
, vol.81
, pp. 1213-1223
-
-
Blomgran, R.1
Zheng, L.2
Stendahl, O.3
-
6
-
-
0037291871
-
A unified model for apical caspase activation
-
Boatright K.M., Renatus M., Scott F.L., Sperandio S., Shin H., Pedersen I.M., Ricci J.E., Edris W.A., Sutherlin D.P., Green D.R., Salvesen G.S. A unified model for apical caspase activation. Mol. Cell 2003, 11:529-541.
-
(2003)
Mol. Cell
, vol.11
, pp. 529-541
-
-
Boatright, K.M.1
Renatus, M.2
Scott, F.L.3
Sperandio, S.4
Shin, H.5
Pedersen, I.M.6
Ricci, J.E.7
Edris, W.A.8
Sutherlin, D.P.9
Green, D.R.10
Salvesen, G.S.11
-
7
-
-
0034054576
-
Selective targeting of lysosomal cysteine proteases with radiolabeled electrophilic substrate analogs
-
Bogyo M., Verhelst S., Bellingard-Dubouchaud V., Toba S., Greenbaum D. Selective targeting of lysosomal cysteine proteases with radiolabeled electrophilic substrate analogs. Chem. Biol. 2000, 7:27-38.
-
(2000)
Chem. Biol.
, vol.7
, pp. 27-38
-
-
Bogyo, M.1
Verhelst, S.2
Bellingard-Dubouchaud, V.3
Toba, S.4
Greenbaum, D.5
-
8
-
-
35548939832
-
Cysteine cathepsins are not involved in Fas/CD95 signalling in primary skin fibroblasts
-
Bojič L., Petelin A., Stoka V., Reinheckel T., Peters C., Turk V., Turk B. Cysteine cathepsins are not involved in Fas/CD95 signalling in primary skin fibroblasts. FEBS Lett. 2007, 581:5185-5190.
-
(2007)
FEBS Lett.
, vol.581
, pp. 5185-5190
-
-
Bojič, L.1
Petelin, A.2
Stoka, V.3
Reinheckel, T.4
Peters, C.5
Turk, V.6
Turk, B.7
-
9
-
-
0038529617
-
Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion
-
Boya P., Andreau K., Poncet D., Zamzami N., Perfettini J.L., Metivier D., Ojcius D.M., Jäättelä M., Kroemer G. Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion. J. Exp. Med. 2003, 197:1323-1334.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 1323-1334
-
-
Boya, P.1
Andreau, K.2
Poncet, D.3
Zamzami, N.4
Perfettini, J.L.5
Metivier, D.6
Ojcius, D.M.7
Jäättelä, M.8
Kroemer, G.9
-
10
-
-
0038677510
-
Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine
-
Boya P., Gonzalez-Polo R.A., Poncet D., Andreau K., Vieira H.L., Roumier T., Perfettini J.L., Kroemer G. Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine. Oncogene 2003, 22:3927-3936.
-
(2003)
Oncogene
, vol.22
, pp. 3927-3936
-
-
Boya, P.1
Gonzalez-Polo, R.A.2
Poncet, D.3
Andreau, K.4
Vieira, H.L.5
Roumier, T.6
Perfettini, J.L.7
Kroemer, G.8
-
11
-
-
70549107710
-
Mitochondrial cell death effectors
-
Brenner D., Mak T.W. Mitochondrial cell death effectors. Curr. Opin. Cell Biol. 2009, 21:871-877.
-
(2009)
Curr. Opin. Cell Biol.
, vol.21
, pp. 871-877
-
-
Brenner, D.1
Mak, T.W.2
-
12
-
-
0034948738
-
The autophagosomal-lysosomal compartment in programmed cell death
-
Bursch W. The autophagosomal-lysosomal compartment in programmed cell death. Cell Death Differ. 2001, 8:569-581.
-
(2001)
Cell Death Differ.
, vol.8
, pp. 569-581
-
-
Bursch, W.1
-
13
-
-
34247899117
-
Three is better than one: pre-ligand receptor assembly in the regulation of TNF receptor signaling
-
Chan F.K. Three is better than one: pre-ligand receptor assembly in the regulation of TNF receptor signaling. Cytokine 2007, 37:101-107.
-
(2007)
Cytokine
, vol.37
, pp. 101-107
-
-
Chan, F.K.1
-
14
-
-
34548014997
-
Reactive oxygen species regulate Bax translocation and mitochondrial transmembrane potential, a possible mechanism for enhanced TRAIL-induced apoptosis by CCCP
-
Chaudhari A.A., Seol J.W., Kim S.J., Lee Y.J., Kang H.S., Kim I.S., Kim N.S., Park S.Y. Reactive oxygen species regulate Bax translocation and mitochondrial transmembrane potential, a possible mechanism for enhanced TRAIL-induced apoptosis by CCCP. Oncol. Rep. 2007, 18:71-76.
-
(2007)
Oncol. Rep.
, vol.18
, pp. 71-76
-
-
Chaudhari, A.A.1
Seol, J.W.2
Kim, S.J.3
Lee, Y.J.4
Kang, H.S.5
Kim, I.S.6
Kim, N.S.7
Park, S.Y.8
-
15
-
-
35848947235
-
Beclin 1-independent pathway of damage-induced mitophagy and autophagic stress: implications for neurodegeneration and cell death
-
Chu C.T., Zhu J., Dagda R. Beclin 1-independent pathway of damage-induced mitophagy and autophagic stress: implications for neurodegeneration and cell death. Autophagy 2007, 3:663-666.
-
(2007)
Autophagy
, vol.3
, pp. 663-666
-
-
Chu, C.T.1
Zhu, J.2
Dagda, R.3
-
16
-
-
0942265544
-
Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of BID by multiple papain-like lysosomal cathepsins
-
Cirman T., Orešič K., Mazovec G.D., Turk V., Reed J.C., Myers R.M., Salvesen G.S., Turk B. Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of BID by multiple papain-like lysosomal cathepsins. J. Biol. Chem. 2004, 279:3578-3587.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 3578-3587
-
-
Cirman, T.1
Orešič, K.2
Mazovec, G.D.3
Turk, V.4
Reed, J.C.5
Myers, R.M.6
Salvesen, G.S.7
Turk, B.8
-
17
-
-
41149098534
-
Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation
-
Conus S., Perozzo R., Reinheckel T., Peters C., Scapozza L., Yousefi S., Simon H.U. Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation. J. Exp. Med. 2008, 205:685-698.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 685-698
-
-
Conus, S.1
Perozzo, R.2
Reinheckel, T.3
Peters, C.4
Scapozza, L.5
Yousefi, S.6
Simon, H.U.7
-
18
-
-
33750979844
-
Mitochondrial membrane remodeling in apoptosis: an inside story
-
Delivani P., Martin S.J. Mitochondrial membrane remodeling in apoptosis: an inside story. Cell Death Differ. 2006, 13:2007-2010.
-
(2006)
Cell Death Differ.
, vol.13
, pp. 2007-2010
-
-
Delivani, P.1
Martin, S.J.2
-
19
-
-
16644383355
-
Dissection of the multiple mechanisms of TNF-alpha-induced apoptosis in liver injury
-
Ding W.X., Yin X.M. Dissection of the multiple mechanisms of TNF-alpha-induced apoptosis in liver injury. J. Cell. Mol. Med. 2004, 8:445-454.
-
(2004)
J. Cell. Mol. Med.
, vol.8
, pp. 445-454
-
-
Ding, W.X.1
Yin, X.M.2
-
20
-
-
0037291890
-
Insights into the regulatory mechanism for caspase-8 activation
-
Donepudi M., Mac Sweeney A., Briand C., Grutter M.G. Insights into the regulatory mechanism for caspase-8 activation. Mol. Cell 2003, 11:543-549.
-
(2003)
Mol. Cell
, vol.11
, pp. 543-549
-
-
Donepudi, M.1
Mac Sweeney, A.2
Briand, C.3
Grutter, M.G.4
-
21
-
-
49649123891
-
Cysteine cathepsins trigger caspase-dependent cell death through cleavage of BID and antiapoptotic Bcl-2 homologues
-
Droga-Mazovec G., Bojič L., Petelin A., Ivanova S., Romih R., Repnik U., Salvesen G.S., Stoka V., Turk V., Turk B. Cysteine cathepsins trigger caspase-dependent cell death through cleavage of BID and antiapoptotic Bcl-2 homologues. J. Biol. Chem. 2008, 283:19140-19150.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 19140-19150
-
-
Droga-Mazovec, G.1
Bojič, L.2
Petelin, A.3
Ivanova, S.4
Romih, R.5
Repnik, U.6
Salvesen, G.S.7
Stoka, V.8
Turk, V.9
Turk, B.10
-
22
-
-
3442880143
-
Sensitization to the lysosomal cell death pathway upon immortalization and transformation
-
Fehrenbacher N., Gyrd-Hansen M., Poulsen B., Felbor U., Kallunki T., Boes M., Weber E., Leist M., Jäättelä M. Sensitization to the lysosomal cell death pathway upon immortalization and transformation. Cancer Res. 2004, 64:5301-5310.
-
(2004)
Cancer Res.
, vol.64
, pp. 5301-5310
-
-
Fehrenbacher, N.1
Gyrd-Hansen, M.2
Poulsen, B.3
Felbor, U.4
Kallunki, T.5
Boes, M.6
Weber, E.7
Leist, M.8
Jäättelä, M.9
-
23
-
-
53049094306
-
Sensitization to the lysosomal cell death pathway by oncogene-induced down-regulation of lysosome-associated membrane proteins 1 and 2
-
Fehrenbacher N., Bastholm L., Kirkegaard-Sorensen T., Rafn B., Bottzauw T., Nielsen C., Weber E., Shirasawa S., Kallunki T., Jäättelä M. Sensitization to the lysosomal cell death pathway by oncogene-induced down-regulation of lysosome-associated membrane proteins 1 and 2. Cancer Res. 2008, 68:6623-6633.
-
(2008)
Cancer Res.
, vol.68
, pp. 6623-6633
-
-
Fehrenbacher, N.1
Bastholm, L.2
Kirkegaard-Sorensen, T.3
Rafn, B.4
Bottzauw, T.5
Nielsen, C.6
Weber, E.7
Shirasawa, S.8
Kallunki, T.9
Jäättelä, M.10
-
24
-
-
33749178260
-
Necrosis, a well-orchestrated form of cell demise: signalling cascades, important mediators and concomitant immune response
-
Festjens N., Vanden Berghe T., Vandenabeele P. Necrosis, a well-orchestrated form of cell demise: signalling cascades, important mediators and concomitant immune response. Biochim. Biophys. Acta 2006, 1757:1371-1387.
-
(2006)
Biochim. Biophys. Acta
, vol.1757
, pp. 1371-1387
-
-
Festjens, N.1
Vanden Berghe, T.2
Vandenabeele, P.3
-
25
-
-
33745966804
-
BH3-only proteins: orchestrating cell death
-
Fletcher J.I., Huang D.C. BH3-only proteins: orchestrating cell death. Cell Death Differ. 2006, 13:1268-1271.
-
(2006)
Cell Death Differ.
, vol.13
, pp. 1268-1271
-
-
Fletcher, J.I.1
Huang, D.C.2
-
26
-
-
0035947776
-
Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor
-
Foghsgaard L., Wissing D., Mauch D., Lademann U., Bastholm L., Boes M., Elling F., Leist M., Jäättelä M. Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor. J. Cell Biol. 2001, 153:999-1010.
-
(2001)
J. Cell Biol.
, vol.153
, pp. 999-1010
-
-
Foghsgaard, L.1
Wissing, D.2
Mauch, D.3
Lademann, U.4
Bastholm, L.5
Boes, M.6
Elling, F.7
Leist, M.8
Jäättelä, M.9
-
27
-
-
33745699393
-
OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion
-
Frezza C., Cipolat S., Martins de Brito O., Micaroni M., Beznoussenko G.V., Rudka T., Bartoli D., Polishuck R.S., Danial N.N., De Strooper B., Scorrano L. OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion. Cell 2006, 126:177-189.
-
(2006)
Cell
, vol.126
, pp. 177-189
-
-
Frezza, C.1
Cipolat, S.2
Martins de Brito, O.3
Micaroni, M.4
Beznoussenko, G.V.5
Rudka, T.6
Bartoli, D.7
Polishuck, R.S.8
Danial, N.N.9
De Strooper, B.10
Scorrano, L.11
-
28
-
-
10644282148
-
The protein structures that shape caspase activity, specificity, activation and inhibition
-
Fuentes-Prior P., Salvesen G.S. The protein structures that shape caspase activity, specificity, activation and inhibition. Biochem. J. 2004, 384:201-232.
-
(2004)
Biochem. J.
, vol.384
, pp. 201-232
-
-
Fuentes-Prior, P.1
Salvesen, G.S.2
-
29
-
-
0035279153
-
Cell type specific involvement of death receptor and mitochondrial pathways in drug-induced apoptosis
-
Fulda S., Meyer E., Friesen C., Susin S.A., Kroemer G., Debatin K.M. Cell type specific involvement of death receptor and mitochondrial pathways in drug-induced apoptosis. Oncogene 2001, 20:1063-1075.
-
(2001)
Oncogene
, vol.20
, pp. 1063-1075
-
-
Fulda, S.1
Meyer, E.2
Friesen, C.3
Susin, S.A.4
Kroemer, G.5
Debatin, K.M.6
-
30
-
-
1842330849
-
Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species. Role of mitochondrial glutathione
-
Garcia-Ruiz C., Colell A., Mari M., Morales A., Fernandez-Checa J.C. Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species. Role of mitochondrial glutathione. J. Biol. Chem. 1997, 272:11369-11377.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 11369-11377
-
-
Garcia-Ruiz, C.1
Colell, A.2
Mari, M.3
Morales, A.4
Fernandez-Checa, J.C.5
-
31
-
-
0037237733
-
Defective TNF-alpha-mediated hepatocellular apoptosis and liver damage in acidic sphingomyelinase knockout mice
-
Garcia-Ruiz C., Colell A., Mari M., Morales A., Calvo M., Enrich C., Fernandez-Checa J.C. Defective TNF-alpha-mediated hepatocellular apoptosis and liver damage in acidic sphingomyelinase knockout mice. J. Clin. Invest. 2003, 111:197-208.
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 197-208
-
-
Garcia-Ruiz, C.1
Colell, A.2
Mari, M.3
Morales, A.4
Calvo, M.5
Enrich, C.6
Fernandez-Checa, J.C.7
-
32
-
-
33746298246
-
Mechanisms of cytochrome c release from mitochondria
-
Garrido C., Galluzzi L., Brunet M., Puig P.E., Didelot C., Kroemer G. Mechanisms of cytochrome c release from mitochondria. Cell Death Differ. 2006, 13:1423-1433.
-
(2006)
Cell Death Differ.
, vol.13
, pp. 1423-1433
-
-
Garrido, C.1
Galluzzi, L.2
Brunet, M.3
Puig, P.E.4
Didelot, C.5
Kroemer, G.6
-
33
-
-
75949130828
-
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
-
Geisler S., Holmstrom K.M., Skujat D., Fiesel F.C., Rothfuss O.C., Kahle P.J., Springer W. PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1. Nat. Cell Biol. 2010, 12:119-131.
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 119-131
-
-
Geisler, S.1
Holmstrom, K.M.2
Skujat, D.3
Fiesel, F.C.4
Rothfuss, O.C.5
Kahle, P.J.6
Springer, W.7
-
34
-
-
0015874481
-
Rupture of rat liver lysosomes mediated by l-amino acid esters
-
Goldman R., Kaplan A. Rupture of rat liver lysosomes mediated by l-amino acid esters. Biochim. Biophys. Acta 1973, 318:205-216.
-
(1973)
Biochim. Biophys. Acta
, vol.318
, pp. 205-216
-
-
Goldman, R.1
Kaplan, A.2
-
35
-
-
0033534446
-
Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death
-
Gross A., Yin X.M., Wang K., Wei M.C., Jockel J., Milliman C., Erdjument-Bromage H., Tempst P., Korsmeyer S.J. Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death. J. Biol. Chem. 1999, 274:1156-1163.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 1156-1163
-
-
Gross, A.1
Yin, X.M.2
Wang, K.3
Wei, M.C.4
Jockel, J.5
Milliman, C.6
Erdjument-Bromage, H.7
Tempst, P.8
Korsmeyer, S.J.9
-
36
-
-
33947235679
-
Vincristine induces dramatic lysosomal changes and sensitizes cancer cells to lysosome-destabilizing siramesine
-
Groth-Pedersen L., Ostenfeld M.S., Hoyer-Hansen M., Nylandsted J., Jäättelä M. Vincristine induces dramatic lysosomal changes and sensitizes cancer cells to lysosome-destabilizing siramesine. Cancer Res. 2007, 67:2217-2225.
-
(2007)
Cancer Res.
, vol.67
, pp. 2217-2225
-
-
Groth-Pedersen, L.1
Ostenfeld, M.S.2
Hoyer-Hansen, M.3
Nylandsted, J.4
Jäättelä, M.5
-
37
-
-
0033756474
-
Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c
-
Guicciardi M.E., Deussing J., Miyoshi H., Bronk S.F., Svingen P.A., Peters C., Kaufmann S.H., Gores G.J. Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c. J. Clin. Invest. 2000, 106:1127-1137.
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 1127-1137
-
-
Guicciardi, M.E.1
Deussing, J.2
Miyoshi, H.3
Bronk, S.F.4
Svingen, P.A.5
Peters, C.6
Kaufmann, S.H.7
Gores, G.J.8
-
39
-
-
22344435528
-
BID is upstream of lysosome-mediated caspase 2 activation in tumor necrosis factor alpha-induced hepatocyte apoptosis
-
Guicciardi M.E., Bronk S.F., Werneburg N.W., Yin X.M., Gores G.J. BID is upstream of lysosome-mediated caspase 2 activation in tumor necrosis factor alpha-induced hepatocyte apoptosis. Gastroenterology 2005, 129:269-284.
-
(2005)
Gastroenterology
, vol.129
, pp. 269-284
-
-
Guicciardi, M.E.1
Bronk, S.F.2
Werneburg, N.W.3
Yin, X.M.4
Gores, G.J.5
-
40
-
-
33750307192
-
Apoptosome-independent activation of the lysosomal cell death pathway by caspase-9
-
Gyrd-Hansen M., Farkas T., Fehrenbacher N., Bastholm L., Hoyer-Hansen M., Elling F., Wallach D., Flavell R., Kroemer G., Nylandsted J., Jäättelä M. Apoptosome-independent activation of the lysosomal cell death pathway by caspase-9. Mol. Cell. Biol. 2006, 26:7880-7891.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 7880-7891
-
-
Gyrd-Hansen, M.1
Farkas, T.2
Fehrenbacher, N.3
Bastholm, L.4
Hoyer-Hansen, M.5
Elling, F.6
Wallach, D.7
Flavell, R.8
Kroemer, G.9
Nylandsted, J.10
Jäättelä, M.11
-
41
-
-
0031973203
-
Importance of the redox state of cytochrome c during caspase activation in cytosolic extracts
-
Hampton M.B., Zhivotovsky B., Slater A.F., Burgess D.H., Orrenius S. Importance of the redox state of cytochrome c during caspase activation in cytosolic extracts. Biochem. J. 1998, 329(Pt 1):95-99.
-
(1998)
Biochem. J.
, vol.329
, Issue.PART 1
, pp. 95-99
-
-
Hampton, M.B.1
Zhivotovsky, B.2
Slater, A.F.3
Burgess, D.H.4
Orrenius, S.5
-
42
-
-
2442661614
-
Cathepsin D links TNF-induced acid sphingomyelinase to BID-mediated caspase-9 and -3 activation
-
Heinrich M., Neumeyer J., Jakob M., Hallas C., Tchikov V., Winoto-Morbach S., Wickel M., Schneider-Brachert W., Trauzold A., Hethke A., Schutze S. Cathepsin D links TNF-induced acid sphingomyelinase to BID-mediated caspase-9 and -3 activation. Cell Death Differ. 2004, 11:550-563.
-
(2004)
Cell Death Differ.
, vol.11
, pp. 550-563
-
-
Heinrich, M.1
Neumeyer, J.2
Jakob, M.3
Hallas, C.4
Tchikov, V.5
Winoto-Morbach, S.6
Wickel, M.7
Schneider-Brachert, W.8
Trauzold, A.9
Hethke, A.10
Schutze, S.11
-
43
-
-
0034641918
-
The biochemistry of apoptosis
-
Hengartner M.O. The biochemistry of apoptosis. Nature 2000, 407:770-776.
-
(2000)
Nature
, vol.407
, pp. 770-776
-
-
Hengartner, M.O.1
-
44
-
-
0348038755
-
Apoptosis caused by cathepsins does not require BID signaling in an in vivo model of progressive myoclonus epilepsy (EPM1)
-
Houseweart M.K., Vilaythong A., Yin X.M., Turk B., Noebels J.L., Myers R.M. Apoptosis caused by cathepsins does not require BID signaling in an in vivo model of progressive myoclonus epilepsy (EPM1). Cell Death Differ. 2003, 10:1329-1335.
-
(2003)
Cell Death Differ.
, vol.10
, pp. 1329-1335
-
-
Houseweart, M.K.1
Vilaythong, A.2
Yin, X.M.3
Turk, B.4
Noebels, J.L.5
Myers, R.M.6
-
45
-
-
48249156591
-
Autophagy: an emerging target for cancer therapy
-
Hoyer-Hansen M., Jäättelä M. Autophagy: an emerging target for cancer therapy. Autophagy 2008, 4:574-580.
-
(2008)
Autophagy
, vol.4
, pp. 574-580
-
-
Hoyer-Hansen, M.1
Jäättelä, M.2
-
46
-
-
0042305977
-
Involvement of lysosomal cysteine proteases in hydrogen peroxide-induced apoptosis in HL-60 cells
-
Ishisaka R., Utsumi K., Utsumi T. Involvement of lysosomal cysteine proteases in hydrogen peroxide-induced apoptosis in HL-60 cells. Biosci. Biotechnol. Biochem. 2002, 66:1865-1872.
-
(2002)
Biosci. Biotechnol. Biochem.
, vol.66
, pp. 1865-1872
-
-
Ishisaka, R.1
Utsumi, K.2
Utsumi, T.3
-
47
-
-
52149105787
-
Lysosomes in apoptosis
-
Ivanova S., Repnik U., Bojič L., Petelin A., Turk V., Turk B. Lysosomes in apoptosis. Methods Enzymol. 2008, 442:183-199.
-
(2008)
Methods Enzymol.
, vol.442
, pp. 183-199
-
-
Ivanova, S.1
Repnik, U.2
Bojič, L.3
Petelin, A.4
Turk, V.5
Turk, B.6
-
48
-
-
23844496672
-
Reactive oxygen species regulate caspase activation in tumor necrosis factor-related apoptosis-inducing ligand-resistant human colon carcinoma cell lines
-
Izeradjene K., Douglas L., Tillman D.M., Delaney A.B., Houghton J.A. Reactive oxygen species regulate caspase activation in tumor necrosis factor-related apoptosis-inducing ligand-resistant human colon carcinoma cell lines. Cancer Res. 2005, 65:7436-7445.
-
(2005)
Cancer Res.
, vol.65
, pp. 7436-7445
-
-
Izeradjene, K.1
Douglas, L.2
Tillman, D.M.3
Delaney, A.B.4
Houghton, J.A.5
-
49
-
-
48249108314
-
Tumor suppression by autophagy through the management of metabolic stress
-
Jin S., White E. Tumor suppression by autophagy through the management of metabolic stress. Autophagy 2008, 4:563-566.
-
(2008)
Autophagy
, vol.4
, pp. 563-566
-
-
Jin, S.1
White, E.2
-
50
-
-
69249208481
-
XIAP discriminates between type I and type II FAS-induced apoptosis
-
Jost P.J., Grabow S., Gray D., McKenzie M.D., Nachbur U., Huang D.C., Bouillet P., Thomas H.E., Borner C., Silke J., Strasser A., Kaufmann T. XIAP discriminates between type I and type II FAS-induced apoptosis. Nature 2009, 460:1035-1039.
-
(2009)
Nature
, vol.460
, pp. 1035-1039
-
-
Jost, P.J.1
Grabow, S.2
Gray, D.3
McKenzie, M.D.4
Nachbur, U.5
Huang, D.C.6
Bouillet, P.7
Thomas, H.E.8
Borner, C.9
Silke, J.10
Strasser, A.11
Kaufmann, T.12
-
51
-
-
0035887215
-
Sphingosine-induced apoptosis is dependent on lysosomal proteases
-
Kågedal K., Zhao M., Svensson I., Brunk U.T. Sphingosine-induced apoptosis is dependent on lysosomal proteases. Biochem. J. 2001, 359:335-343.
-
(2001)
Biochem. J.
, vol.359
, pp. 335-343
-
-
Kågedal, K.1
Zhao, M.2
Svensson, I.3
Brunk, U.T.4
-
53
-
-
70449091753
-
Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis
-
Kim H., Tu H.C., Ren D., Takeuchi O., Jeffers J.R., Zambetti G.P., Hsieh J.J., Cheng E.H. Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis. Mol. Cell 2009, 36:487-499.
-
(2009)
Mol. Cell
, vol.36
, pp. 487-499
-
-
Kim, H.1
Tu, H.C.2
Ren, D.3
Takeuchi, O.4
Jeffers, J.R.5
Zambetti, G.P.6
Hsieh, J.J.7
Cheng, E.H.8
-
54
-
-
62949128915
-
Lysosomal involvement in cell death and cancer
-
Kirkegaard T., Jäättelä M. Lysosomal involvement in cell death and cancer. Biochim. Biophys. Acta 2009, 1793:746-754.
-
(2009)
Biochim. Biophys. Acta
, vol.1793
, pp. 746-754
-
-
Kirkegaard, T.1
Jäättelä, M.2
-
55
-
-
75749102680
-
Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated lysosomal pathology
-
Kirkegaard T., Roth A.G., Petersen N.H., Mahalka A.K., Olsen O.D., Moilanen I., Zylicz A., Knudsen J., Sandhoff K., Arenz C., Kinnunen P.K., Nylandsted J., Jäättelä M. Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated lysosomal pathology. Nature 2010, 463:549-553.
-
(2010)
Nature
, vol.463
, pp. 549-553
-
-
Kirkegaard, T.1
Roth, A.G.2
Petersen, N.H.3
Mahalka, A.K.4
Olsen, O.D.5
Moilanen, I.6
Zylicz, A.7
Knudsen, J.8
Sandhoff, K.9
Arenz, C.10
Kinnunen, P.K.11
Nylandsted, J.12
Jäättelä, M.13
-
56
-
-
69249225572
-
Cysteine cathepsins are not critical for TNF-alpha-induced cell death in T98G and U937 cells
-
Klarič M., Tao S., Stoka V., Turk B., Turk V. Cysteine cathepsins are not critical for TNF-alpha-induced cell death in T98G and U937 cells. Biochim. Biophys. Acta 2009, 1794:1372-1377.
-
(2009)
Biochim. Biophys. Acta
, vol.1794
, pp. 1372-1377
-
-
Klarič, M.1
Tao, S.2
Stoka, V.3
Turk, B.4
Turk, V.5
-
57
-
-
21044455137
-
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice
-
Komatsu M., Waguri S., Ueno T., Iwata J., Murata S., Tanida I., Ezaki J., Mizushima N., Ohsumi Y., Uchiyama Y., Kominami E., Tanaka K., Chiba T. Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice. J. Cell Biol. 2005, 169:425-434.
-
(2005)
J. Cell Biol.
, vol.169
, pp. 425-434
-
-
Komatsu, M.1
Waguri, S.2
Ueno, T.3
Iwata, J.4
Murata, S.5
Tanida, I.6
Ezaki, J.7
Mizushima, N.8
Ohsumi, Y.9
Uchiyama, Y.10
Kominami, E.11
Tanaka, K.12
Chiba, T.13
-
58
-
-
0034523818
-
Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c
-
Korsmeyer S.J., Wei M.C., Saito M., Weiler S., Oh K.J., Schlesinger P.H. Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c. Cell Death Differ. 2000, 7:1166-1173.
-
(2000)
Cell Death Differ.
, vol.7
, pp. 1166-1173
-
-
Korsmeyer, S.J.1
Wei, M.C.2
Saito, M.3
Weiler, S.4
Oh, K.J.5
Schlesinger, P.H.6
-
59
-
-
56749170677
-
Autophagic cell death: the story of a misnomer
-
Kroemer G., Levine B. Autophagic cell death: the story of a misnomer. Nat. Rev. Mol. Cell Biol. 2008, 9:1004-1010.
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 1004-1010
-
-
Kroemer, G.1
Levine, B.2
-
60
-
-
0344631776
-
Biophysics of ceramide signaling: interaction with proteins and phase transition of membranes
-
Kronke M. Biophysics of ceramide signaling: interaction with proteins and phase transition of membranes. Chem. Phys. Lipids 1999, 101:109-121.
-
(1999)
Chem. Phys. Lipids
, vol.101
, pp. 109-121
-
-
Kronke, M.1
-
61
-
-
33745205646
-
Intralysosomal iron chelation protects against oxidative stress-induced cellular damage
-
Kurz T., Gustafsson B., Brunk U.T. Intralysosomal iron chelation protects against oxidative stress-induced cellular damage. FEBS J. 2006, 273:3106-3117.
-
(2006)
FEBS J.
, vol.273
, pp. 3106-3117
-
-
Kurz, T.1
Gustafsson, B.2
Brunk, U.T.3
-
62
-
-
34249815482
-
Autophagy, ageing and apoptosis: the role of oxidative stress and lysosomal iron
-
Kurz T., Terman A., Brunk U.T. Autophagy, ageing and apoptosis: the role of oxidative stress and lysosomal iron. Arch. Biochem. Biophys. 2007, 462:220-230.
-
(2007)
Arch. Biochem. Biophys.
, vol.462
, pp. 220-230
-
-
Kurz, T.1
Terman, A.2
Brunk, U.T.3
-
63
-
-
0035433420
-
Four deaths and a funeral: from caspases to alternative mechanisms
-
Leist M., Jäättelä M. Four deaths and a funeral: from caspases to alternative mechanisms. Nat. Rev. Mol. Cell Biol. 2001, 2:589-598.
-
(2001)
Nat. Rev. Mol. Cell Biol.
, vol.2
, pp. 589-598
-
-
Leist, M.1
Jäättelä, M.2
-
64
-
-
0032555697
-
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
-
Li H., Zhu H., Xu C.J., Yuan J. Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 1998, 94:491-501.
-
(1998)
Cell
, vol.94
, pp. 491-501
-
-
Li, H.1
Zhu, H.2
Xu, C.J.3
Yuan, J.4
-
65
-
-
0034677741
-
Induction of cell death by the lysosomotropic detergent MSDH
-
Li W., Yuan X., Nordgren G., Dalen H., Dubowchik G.M., Firestone R.A., Brunk U.T. Induction of cell death by the lysosomotropic detergent MSDH. FEBS Lett. 2000, 470:35-39.
-
(2000)
FEBS Lett.
, vol.470
, pp. 35-39
-
-
Li, W.1
Yuan, X.2
Nordgren, G.3
Dalen, H.4
Dubowchik, G.M.5
Firestone, R.A.6
Brunk, U.T.7
-
66
-
-
0032555716
-
BID, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
-
Luo X., Budihardjo I., Zou H., Slaughter C., Wang X. BID, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 1998, 94:481-490.
-
(1998)
Cell
, vol.94
, pp. 481-490
-
-
Luo, X.1
Budihardjo, I.2
Zou, H.3
Slaughter, C.4
Wang, X.5
-
68
-
-
34548188741
-
Self-eating and self-killing: crosstalk between autophagy and apoptosis
-
Maiuri M.C., Zalckvar E., Kimchi A., Kroemer G. Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nat. Rev. Mol. Cell Biol. 2007, 8:741-752.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 741-752
-
-
Maiuri, M.C.1
Zalckvar, E.2
Kimchi, A.3
Kroemer, G.4
-
69
-
-
0021069160
-
Cell killing by lysosomotropic detergents
-
Miller D.K., Griffiths E., Lenard J., Firestone R.A. Cell killing by lysosomotropic detergents. J. Cell Biol. 1983, 97:1841-1851.
-
(1983)
J. Cell Biol.
, vol.97
, pp. 1841-1851
-
-
Miller, D.K.1
Griffiths, E.2
Lenard, J.3
Firestone, R.A.4
-
70
-
-
34447516996
-
A Bax/Bak-independent mechanism of cytochrome c release
-
Mizuta T., Shimizu S., Matsuoka Y., Nakagawa T., Tsujimoto Y. A Bax/Bak-independent mechanism of cytochrome c release. J. Biol. Chem. 2007, 282:16623-16630.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 16623-16630
-
-
Mizuta, T.1
Shimizu, S.2
Matsuoka, Y.3
Nakagawa, T.4
Tsujimoto, Y.5
-
71
-
-
0036661078
-
CA-074, but not its methyl ester CA-074Me, is a selective inhibitor of cathepsin B within living cells
-
Montaser M., Lalmanach G., Mach L. CA-074, but not its methyl ester CA-074Me, is a selective inhibitor of cathepsin B within living cells. Biol. Chem. 2002, 383:1305-1308.
-
(2002)
Biol. Chem.
, vol.383
, pp. 1305-1308
-
-
Montaser, M.1
Lalmanach, G.2
Mach, L.3
-
73
-
-
33746690768
-
TNF-receptor I defective in internalization allows for cell death through activation of neutral sphingomyelinase
-
Neumeyer J., Hallas C., Merkel O., Winoto-Morbach S., Jakob M., Thon L., Adam D., Schneider-Brachert W., Schutze S. TNF-receptor I defective in internalization allows for cell death through activation of neutral sphingomyelinase. Exp. Cell Res. 2006, 312:2142-2153.
-
(2006)
Exp. Cell Res.
, vol.312
, pp. 2142-2153
-
-
Neumeyer, J.1
Hallas, C.2
Merkel, O.3
Winoto-Morbach, S.4
Jakob, M.5
Thon, L.6
Adam, D.7
Schneider-Brachert, W.8
Schutze, S.9
-
74
-
-
4344651318
-
Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization
-
Nylandsted J., Gyrd-Hansen M., Danielewicz A., Fehrenbacher N., Lademann U., Hoyer-Hansen M., Weber E., Multhoff G., Rohde M., Jäättelä M. Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization. J. Exp. Med. 2004, 200:425-435.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 425-435
-
-
Nylandsted, J.1
Gyrd-Hansen, M.2
Danielewicz, A.3
Fehrenbacher, N.4
Lademann, U.5
Hoyer-Hansen, M.6
Weber, E.7
Multhoff, G.8
Rohde, M.9
Jäättelä, M.10
-
75
-
-
77953617179
-
Lysosomal membrane permeabilization and cathepsin release is a Bax/Bak-dependent, amplifying event of apoptosis in fibroblasts and monocytes
-
Oberle C., Huai J., Reinheckel T., Tacke M., Rassner M., Ekert P.G., Buellesbach J., Borner C. Lysosomal membrane permeabilization and cathepsin release is a Bax/Bak-dependent, amplifying event of apoptosis in fibroblasts and monocytes. Cell Death Differ. 2010, 17:1167-1178.
-
(2010)
Cell Death Differ.
, vol.17
, pp. 1167-1178
-
-
Oberle, C.1
Huai, J.2
Reinheckel, T.3
Tacke, M.4
Rassner, M.5
Ekert, P.G.6
Buellesbach, J.7
Borner, C.8
-
76
-
-
67650246357
-
Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy
-
Okamoto K., Kondo-Okamoto N., Ohsumi Y. Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy. Dev. Cell 2009, 17:87-97.
-
(2009)
Dev. Cell
, vol.17
, pp. 87-97
-
-
Okamoto, K.1
Kondo-Okamoto, N.2
Ohsumi, Y.3
-
77
-
-
25444483322
-
Effective tumor cell death by sigma-2 receptor ligand siramesine involves lysosomal leakage and oxidative stress
-
Ostenfeld M.S., Fehrenbacher N., Hoyer-Hansen M., Thomsen C., Farkas T., Jäättelä M. Effective tumor cell death by sigma-2 receptor ligand siramesine involves lysosomal leakage and oxidative stress. Cancer Res. 2005, 65:8975-8983.
-
(2005)
Cancer Res.
, vol.65
, pp. 8975-8983
-
-
Ostenfeld, M.S.1
Fehrenbacher, N.2
Hoyer-Hansen, M.3
Thomsen, C.4
Farkas, T.5
Jäättelä, M.6
-
78
-
-
0037022352
-
Cytochrome c release from mitochondria proceeds by a two-step process
-
Ott M., Robertson J.D., Gogvadze V., Zhivotovsky B., Orrenius S. Cytochrome c release from mitochondria proceeds by a two-step process. Proc. Natl Acad. Sci. USA 2002, 99:1259-1263.
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 1259-1263
-
-
Ott, M.1
Robertson, J.D.2
Gogvadze, V.3
Zhivotovsky, B.4
Orrenius, S.5
-
79
-
-
45849085339
-
Cytochrome c: functions beyond respiration
-
Ow Y.P., Green D.R., Hao Z., Mak T.W. Cytochrome c: functions beyond respiration. Nat. Rev. Mol. Cell Biol. 2008, 9:532-542.
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 532-542
-
-
Ow, Y.P.1
Green, D.R.2
Hao, Z.3
Mak, T.W.4
-
80
-
-
75749152640
-
The Polycomb group protein EED couples TNF receptor 1 to neutral sphingomyelinase
-
Philipp S., Puchert M., Adam-Klages S., Tchikov V., Winoto-Morbach S., Mathieu S., Deerberg A., Kolker L., Marchesini N., Kabelitz D., Hannun Y.A., Schutze S., Adam D. The Polycomb group protein EED couples TNF receptor 1 to neutral sphingomyelinase. Proc. Natl Acad. Sci. USA 2010, 107:1112-1117.
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 1112-1117
-
-
Philipp, S.1
Puchert, M.2
Adam-Klages, S.3
Tchikov, V.4
Winoto-Morbach, S.5
Mathieu, S.6
Deerberg, A.7
Kolker, L.8
Marchesini, N.9
Kabelitz, D.10
Hannun, Y.A.11
Schutze, S.12
Adam, D.13
-
81
-
-
33646024628
-
The apoptosome activates caspase-9 by dimerization
-
Pop C., Timmer J., Sperandio S., Salvesen G.S. The apoptosome activates caspase-9 by dimerization. Mol. Cell 2006, 22:269-275.
-
(2006)
Mol. Cell
, vol.22
, pp. 269-275
-
-
Pop, C.1
Timmer, J.2
Sperandio, S.3
Salvesen, G.S.4
-
82
-
-
34147178164
-
Role of proteolysis in caspase-8 activation and stabilization
-
Pop C., Fitzgerald P., Green D.R., Salvesen G.S. Role of proteolysis in caspase-8 activation and stabilization. Biochemistry 2007, 46:4398-4407.
-
(2007)
Biochemistry
, vol.46
, pp. 4398-4407
-
-
Pop, C.1
Fitzgerald, P.2
Green, D.R.3
Salvesen, G.S.4
-
83
-
-
62949097187
-
Delivery of endocytosed membrane proteins to the lysosome
-
Pryor P.R., Luzio J.P. Delivery of endocytosed membrane proteins to the lysosome. Biochim. Biophys. Acta 2009, 1793:615-624.
-
(2009)
Biochim. Biophys. Acta
, vol.1793
, pp. 615-624
-
-
Pryor, P.R.1
Luzio, J.P.2
-
84
-
-
38349132722
-
Amplification of CD95 activation by caspase 8-induced endosomal acidification in rat hepatocytes
-
Reinehr R., Sommerfeld A., Keitel V., Grether-Beck S., Haussinger D. Amplification of CD95 activation by caspase 8-induced endosomal acidification in rat hepatocytes. J. Biol. Chem. 2008, 283:2211-2222.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 2211-2222
-
-
Reinehr, R.1
Sommerfeld, A.2
Keitel, V.3
Grether-Beck, S.4
Haussinger, D.5
-
85
-
-
34247345833
-
The apoptosome: signalling platform of cell death
-
Riedl S.J., Salvesen G.S. The apoptosome: signalling platform of cell death. Nat. Rev. Mol. Cell Biol. 2007, 8:405-413.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 405-413
-
-
Riedl, S.J.1
Salvesen, G.S.2
-
86
-
-
0035909889
-
Structural basis for the activation of human procaspase-7
-
Riedl S.J., Fuentes-Prior P., Renatus M., Kairies N., Krapp S., Huber R., Salvesen G.S., Bode W. Structural basis for the activation of human procaspase-7. Proc. Natl Acad. Sci. USA 2001, 98:14790-14795.
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 14790-14795
-
-
Riedl, S.J.1
Fuentes-Prior, P.2
Renatus, M.3
Kairies, N.4
Krapp, S.5
Huber, R.6
Salvesen, G.S.7
Bode, W.8
-
87
-
-
33644606491
-
Tracker dyes to probe mitochondrial autophagy (mitophagy) in rat hepatocytes
-
Rodriguez-Enriquez S., Kim I., Currin R.T., Lemasters J.J. Tracker dyes to probe mitochondrial autophagy (mitophagy) in rat hepatocytes. Autophagy 2006, 2:39-46.
-
(2006)
Autophagy
, vol.2
, pp. 39-46
-
-
Rodriguez-Enriquez, S.1
Kim, I.2
Currin, R.T.3
Lemasters, J.J.4
-
88
-
-
69249227502
-
Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function
-
Saftig P., Klumperman J. Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function. Nat. Rev. Mol. Cell Biol. 2009, 10:623-635.
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 623-635
-
-
Saftig, P.1
Klumperman, J.2
-
89
-
-
77949488942
-
Calpain-mediated Hsp70.1 cleavage in hippocampal CA1 neuronal death
-
Sahara S., Yamashima T. Calpain-mediated Hsp70.1 cleavage in hippocampal CA1 neuronal death. Biochem. Biophys. Res. Commun. 2010, 393:806-811.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.393
, pp. 806-811
-
-
Sahara, S.1
Yamashima, T.2
-
90
-
-
0035164416
-
A lysosomal protease enters the death scene
-
Salvesen G.S. A lysosomal protease enters the death scene. J. Clin. Invest. 2001, 107:21-22.
-
(2001)
J. Clin. Invest.
, vol.107
, pp. 21-22
-
-
Salvesen, G.S.1
-
91
-
-
24944502572
-
Tumor necrosis factor-related apoptosis-inducing ligand alters mitochondrial membrane lipids
-
Sandra F., Degli Esposti M., Ndebele K., Gona P., Knight D., Rosenquist M., Khosravi-Far R. Tumor necrosis factor-related apoptosis-inducing ligand alters mitochondrial membrane lipids. Cancer Res. 2005, 65:8286-8297.
-
(2005)
Cancer Res.
, vol.65
, pp. 8286-8297
-
-
Sandra, F.1
Degli Esposti, M.2
Ndebele, K.3
Gona, P.4
Knight, D.5
Rosenquist, M.6
Khosravi-Far, R.7
-
92
-
-
0032536771
-
Two CD95 (APO-1/Fas) signaling pathways
-
Scaffidi C., Fulda S., Srinivasan A., Friesen C., Li F., Tomaselli K.J., Debatin K.M., Krammer P.H., Peter M.E. Two CD95 (APO-1/Fas) signaling pathways. EMBO J. 1998, 17:1675-1687.
-
(1998)
EMBO J.
, vol.17
, pp. 1675-1687
-
-
Scaffidi, C.1
Fulda, S.2
Srinivasan, A.3
Friesen, C.4
Li, F.5
Tomaselli, K.J.6
Debatin, K.M.7
Krammer, P.H.8
Peter, M.E.9
-
93
-
-
4444341939
-
Compartmentalization of TNF receptor 1 signaling: internalized TNF receptosomes as death signaling vesicles
-
Schneider-Brachert W., Tchikov V., Neumeyer J., Jakob M., Winoto-Morbach S., Held-Feindt J., Heinrich M., Merkel O., Ehrenschwender M., Adam D., Mentlein R., Kabelitz D., Schutze S. Compartmentalization of TNF receptor 1 signaling: internalized TNF receptosomes as death signaling vesicles. Immunity 2004, 21:415-428.
-
(2004)
Immunity
, vol.21
, pp. 415-428
-
-
Schneider-Brachert, W.1
Tchikov, V.2
Neumeyer, J.3
Jakob, M.4
Winoto-Morbach, S.5
Held-Feindt, J.6
Heinrich, M.7
Merkel, O.8
Ehrenschwender, M.9
Adam, D.10
Mentlein, R.11
Kabelitz, D.12
Schutze, S.13
-
94
-
-
72949108579
-
Impact of TNF-R1 and CD95 internalization on apoptotic and antiapoptotic signaling
-
Schutze S., Schneider-Brachert W. Impact of TNF-R1 and CD95 internalization on apoptotic and antiapoptotic signaling. Results Probl. Cell Differ. 2009, 49:63-85.
-
(2009)
Results Probl. Cell Differ.
, vol.49
, pp. 63-85
-
-
Schutze, S.1
Schneider-Brachert, W.2
-
95
-
-
0037427412
-
Mechanisms of cytochrome c release by proapoptotic BCL-2 family members
-
Scorrano L., Korsmeyer S.J. Mechanisms of cytochrome c release by proapoptotic BCL-2 family members. Biochem. Biophys. Res. Commun. 2003, 304:437-444.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.304
, pp. 437-444
-
-
Scorrano, L.1
Korsmeyer, S.J.2
-
96
-
-
60549106191
-
The Fas-FADD death domain complex structure unravels signalling by receptor clustering
-
Scott F.L., Stec B., Pop C., Dobaczewska M.K., Lee J.J., Monosov E., Robinson H., Salvesen G.S., Schwarzenbacher R., Riedl S.J. The Fas-FADD death domain complex structure unravels signalling by receptor clustering. Nature 2009, 457:1019-1022.
-
(2009)
Nature
, vol.457
, pp. 1019-1022
-
-
Scott, F.L.1
Stec, B.2
Pop, C.3
Dobaczewska, M.K.4
Lee, J.J.5
Monosov, E.6
Robinson, H.7
Salvesen, G.S.8
Schwarzenbacher, R.9
Riedl, S.J.10
-
97
-
-
67650162495
-
Peroxiredoxin I contributes to TRAIL resistance through suppression of redox-sensitive caspase activation in human hepatoma cells
-
Song I.S., Kim S.U., Oh N.S., Kim J., Yu D.Y., Huang S.M., Kim J.M., Lee D.S., Kim N.S. Peroxiredoxin I contributes to TRAIL resistance through suppression of redox-sensitive caspase activation in human hepatoma cells. Carcinogenesis 2009, 30:1106-1114.
-
(2009)
Carcinogenesis
, vol.30
, pp. 1106-1114
-
-
Song, I.S.1
Kim, S.U.2
Oh, N.S.3
Kim, J.4
Yu, D.Y.5
Huang, S.M.6
Kim, J.M.7
Lee, D.S.8
Kim, N.S.9
-
98
-
-
0035793580
-
Lysosomal protease pathways to apoptosis. Cleavage of BID, not pro-caspases, is the most likely route
-
Stoka V., Turk B., Schendel S.L., Kim T.H., Cirman T., Snipas S.J., Ellerby L.M., Bredesen D., Freeze H., Abrahamson M., Bromme D., Krajewski S., Reed J.C., Yin X.M., Turk V., Salvesen G.S. Lysosomal protease pathways to apoptosis. Cleavage of BID, not pro-caspases, is the most likely route. J. Biol. Chem. 2001, 276:3149-3157.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 3149-3157
-
-
Stoka, V.1
Turk, B.2
Schendel, S.L.3
Kim, T.H.4
Cirman, T.5
Snipas, S.J.6
Ellerby, L.M.7
Bredesen, D.8
Freeze, H.9
Abrahamson, M.10
Bromme, D.11
Krajewski, S.12
Reed, J.C.13
Yin, X.M.14
Turk, V.15
Salvesen, G.S.16
-
99
-
-
33747600931
-
Do lysosomes induce cell death?
-
Stoka V., Turk V., Turk B. Do lysosomes induce cell death?. IUBMB Life 2006, 58:493-494.
-
(2006)
IUBMB Life
, vol.58
, pp. 493-494
-
-
Stoka, V.1
Turk, V.2
Turk, B.3
-
100
-
-
34250020188
-
Lysosomal cysteine cathepsins: signaling pathways in apoptosis
-
Stoka V., Turk V., Turk B. Lysosomal cysteine cathepsins: signaling pathways in apoptosis. Biol. Chem. 2007, 388:555-560.
-
(2007)
Biol. Chem.
, vol.388
, pp. 555-560
-
-
Stoka, V.1
Turk, V.2
Turk, B.3
-
101
-
-
0742324395
-
Mitochondrial protease Omi/HtrA2 enhances caspase activation through multiple pathways
-
Suzuki Y., Takahashi-Niki K., Akagi T., Hashikawa T., Takahashi R. Mitochondrial protease Omi/HtrA2 enhances caspase activation through multiple pathways. Cell Death Differ. 2004, 11:208-216.
-
(2004)
Cell Death Differ.
, vol.11
, pp. 208-216
-
-
Suzuki, Y.1
Takahashi-Niki, K.2
Akagi, T.3
Hashikawa, T.4
Takahashi, R.5
-
103
-
-
33749656530
-
The lysosomal-mitochondrial axis theory of postmitotic aging and cell death
-
Terman A., Gustafsson B., Brunk U.T. The lysosomal-mitochondrial axis theory of postmitotic aging and cell death. Chem. Biol. Interact. 2006, 163:29-37.
-
(2006)
Chem. Biol. Interact.
, vol.163
, pp. 29-37
-
-
Terman, A.1
Gustafsson, B.2
Brunk, U.T.3
-
104
-
-
34249893895
-
Protease signalling in cell death: caspases versus cysteine cathepsins
-
Turk B., Stoka V. Protease signalling in cell death: caspases versus cysteine cathepsins. FEBS Lett. 2007, 581:2761-2767.
-
(2007)
FEBS Lett.
, vol.581
, pp. 2761-2767
-
-
Turk, B.1
Stoka, V.2
-
105
-
-
69249140641
-
Lysosomes as "suicide bags" in cell death: myth or reality?
-
Turk B., Turk V. Lysosomes as "suicide bags" in cell death: myth or reality?. J. Biol. Chem. 2009, 284:21783-21787.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 21783-21787
-
-
Turk, B.1
Turk, V.2
-
106
-
-
0027459566
-
Kinetics of the pH-induced inactivation of human cathepsin L
-
Turk B., Dolenc I., Turk V., Bieth J.G. Kinetics of the pH-induced inactivation of human cathepsin L. Biochemistry 1993, 32:375-380.
-
(1993)
Biochemistry
, vol.32
, pp. 375-380
-
-
Turk, B.1
Dolenc, I.2
Turk, V.3
Bieth, J.G.4
-
107
-
-
0029284365
-
Regulation of the activity of lysosomal cysteine proteinases by pH-induced inactivation and/or endogenous protein inhibitors, cystatins
-
Turk B., Bieth J.G., Bjork I., Dolenc I., Turk D., Cimerman N., Kos J., Čolić A., Stoka V., Turk V. Regulation of the activity of lysosomal cysteine proteinases by pH-induced inactivation and/or endogenous protein inhibitors, cystatins. Biol. Chem. Hoppe Seyler 1995, 376:225-230.
-
(1995)
Biol. Chem. Hoppe Seyler
, vol.376
, pp. 225-230
-
-
Turk, B.1
Bieth, J.G.2
Bjork, I.3
Dolenc, I.4
Turk, D.5
Cimerman, N.6
Kos, J.7
Čolić, A.8
Stoka, V.9
Turk, V.10
-
108
-
-
0035801514
-
Lysosomal cysteine proteases: facts and opportunities
-
Turk V., Turk B., Turk D. Lysosomal cysteine proteases: facts and opportunities. EMBO J. 2001, 20:4629-4633.
-
(2001)
EMBO J.
, vol.20
, pp. 4629-4633
-
-
Turk, V.1
Turk, B.2
Turk, D.3
-
109
-
-
0035986219
-
Regulating cysteine protease activity: essential role of protease inhibitors as guardians and regulators
-
Turk B., Turk D., Salvesen G.S. Regulating cysteine protease activity: essential role of protease inhibitors as guardians and regulators. Curr. Pharm. Des. 2002, 8:1623-1637.
-
(2002)
Curr. Pharm. Des.
, vol.8
, pp. 1623-1637
-
-
Turk, B.1
Turk, D.2
Salvesen, G.S.3
-
110
-
-
23944522127
-
Regulting cysteine protease activity: essential role of protease inhibitors as guardians and regulators
-
Turk B., Turk D., Salvesen G.S. Regulting cysteine protease activity: essential role of protease inhibitors as guardians and regulators. Med. Chem. Rev. - Online 2005, 2:283-297.
-
(2005)
Med. Chem. Rev. - Online
, vol.2
, pp. 283-297
-
-
Turk, B.1
Turk, D.2
Salvesen, G.S.3
-
111
-
-
52049096824
-
Cystatins: biochemical and structural properties, and medical relevance
-
Turk V., Stoka V., Turk D. Cystatins: biochemical and structural properties, and medical relevance. Front. Biosci. 2008, 13:5406-5420.
-
(2008)
Front. Biosci.
, vol.13
, pp. 5406-5420
-
-
Turk, V.1
Stoka, V.2
Turk, D.3
-
112
-
-
38549110110
-
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
-
Twig G., Elorza A., Molina A.J., Mohamed H., Wikstrom J.D., Walzer G., Stiles L., Haigh S.E., Katz S., Las G., Alroy J., Wu M., Py B.F., Yuan J., Deeney J.T., Corkey B.E., Shirihai O.S. Fission and selective fusion govern mitochondrial segregation and elimination by autophagy. EMBO J. 2008, 27:433-446.
-
(2008)
EMBO J.
, vol.27
, pp. 433-446
-
-
Twig, G.1
Elorza, A.2
Molina, A.J.3
Mohamed, H.4
Wikstrom, J.D.5
Walzer, G.6
Stiles, L.7
Haigh, S.E.8
Katz, S.9
Las, G.10
Alroy, J.11
Wu, M.12
Py, B.F.13
Yuan, J.14
Deeney, J.T.15
Corkey, B.E.16
Shirihai, O.S.17
-
113
-
-
0032728949
-
Mechanism of apoptosis induced by a lysosomotropic agent, L-Leucyl-L-Leucine methyl ester
-
Uchimoto T., Nohara H., Kamehara R., Iwamura M., Watanabe N., Kobayashi Y. Mechanism of apoptosis induced by a lysosomotropic agent, L-Leucyl-L-Leucine methyl ester. Apoptosis 1999, 4:357-362.
-
(1999)
Apoptosis
, vol.4
, pp. 357-362
-
-
Uchimoto, T.1
Nohara, H.2
Kamehara, R.3
Iwamura, M.4
Watanabe, N.5
Kobayashi, Y.6
-
114
-
-
33947604810
-
Emerging roles of cysteine cathepsins in disease and their potential as drug targets
-
Vasiljeva O., Reinheckel T., Peters C., Turk D., Turk V., Turk B. Emerging roles of cysteine cathepsins in disease and their potential as drug targets. Curr. Pharm. Des. 2007, 13:387-403.
-
(2007)
Curr. Pharm. Des.
, vol.13
, pp. 387-403
-
-
Vasiljeva, O.1
Reinheckel, T.2
Peters, C.3
Turk, D.4
Turk, V.5
Turk, B.6
-
115
-
-
47049095033
-
Reduced tumour cell proliferation and delayed development of high-grade mammary carcinomas in cathepsin B-deficient mice
-
Vasiljeva O., Korovin M., Gajda M., Brodoefel H., Bojič L., Kruger A., Schurigt U., Sevenich L., Turk B., Peters C., Reinheckel T. Reduced tumour cell proliferation and delayed development of high-grade mammary carcinomas in cathepsin B-deficient mice. Oncogene 2008, 27:4191-4199.
-
(2008)
Oncogene
, vol.27
, pp. 4191-4199
-
-
Vasiljeva, O.1
Korovin, M.2
Gajda, M.3
Brodoefel, H.4
Bojič, L.5
Kruger, A.6
Schurigt, U.7
Sevenich, L.8
Turk, B.9
Peters, C.10
Reinheckel, T.11
-
116
-
-
57049132739
-
Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c
-
Vaughn A.E., Deshmukh M. Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c. Nat. Cell Biol. 2008, 10:1477-1483.
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 1477-1483
-
-
Vaughn, A.E.1
Deshmukh, M.2
-
117
-
-
43749124428
-
Chelerythrine induces apoptosis through a Bax/Bak-independent mitochondrial mechanism
-
Wan K.F., Chan S.L., Sukumaran S.K., Lee M.C., Yu V.C. Chelerythrine induces apoptosis through a Bax/Bak-independent mitochondrial mechanism. J. Biol. Chem. 2008, 283:8423-8433.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 8423-8433
-
-
Wan, K.F.1
Chan, S.L.2
Sukumaran, S.K.3
Lee, M.C.4
Yu, V.C.5
-
118
-
-
34147186302
-
Lysosomes and Fas-mediated liver cell death
-
Wattiaux R., Wattiaux-de Coninck S., Thirion J., Gasingirwa M.C., Jadot M. Lysosomes and Fas-mediated liver cell death. Biochem. J. 2007, 403:89-95.
-
(2007)
Biochem. J.
, vol.403
, pp. 89-95
-
-
Wattiaux, R.1
Wattiaux-de Coninck, S.2
Thirion, J.3
Gasingirwa, M.C.4
Jadot, M.5
-
119
-
-
0038408712
-
Hurpin is a selective inhibitor of lysosomal cathepsin L and protects keratinocytes from ultraviolet-induced apoptosis
-
Welss T., Sun J., Irving J.A., Blum R., Smith A.I., Whisstock J.C., Pike R.N., von Mikecz A., Ruzicka T., Bird P.I., Abts H.F. Hurpin is a selective inhibitor of lysosomal cathepsin L and protects keratinocytes from ultraviolet-induced apoptosis. Biochemistry 2003, 42:7381-7389.
-
(2003)
Biochemistry
, vol.42
, pp. 7381-7389
-
-
Welss, T.1
Sun, J.2
Irving, J.A.3
Blum, R.4
Smith, A.I.5
Whisstock, J.C.6
Pike, R.N.7
von Mikecz, A.8
Ruzicka, T.9
Bird, P.I.10
Abts, H.F.11
-
122
-
-
35348948380
-
Tumor necrosis factor-related apoptosis-inducing ligand activates a lysosomal pathway of apoptosis that is regulated by Bcl-2 proteins
-
Werneburg N.W., Guicciardi M.E., Bronk S.F., Kaufmann S.H., Gores G.J. Tumor necrosis factor-related apoptosis-inducing ligand activates a lysosomal pathway of apoptosis that is regulated by Bcl-2 proteins. J. Biol. Chem. 2007, 282:28960-28970.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 28960-28970
-
-
Werneburg, N.W.1
Guicciardi, M.E.2
Bronk, S.F.3
Kaufmann, S.H.4
Gores, G.J.5
-
123
-
-
43949131433
-
Autophagic cell death unraveled: pharmacological inhibition of apoptosis and autophagy enables necrosis
-
White E. Autophagic cell death unraveled: pharmacological inhibition of apoptosis and autophagy enables necrosis. Autophagy 2008, 4:399-401.
-
(2008)
Autophagy
, vol.4
, pp. 399-401
-
-
White, E.1
-
124
-
-
10944247878
-
Neutralization of Smac/Diablo by inhibitors of apoptosis (IAPs). A caspase-independent mechanism for apoptotic inhibition
-
Wilkinson J.C., Wilkinson A.S., Scott F.L., Csomos R.A., Salvesen G.S., Duckett C.S. Neutralization of Smac/Diablo by inhibitors of apoptosis (IAPs). A caspase-independent mechanism for apoptotic inhibition. J. Biol. Chem. 2004, 279:51082-51090.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 51082-51090
-
-
Wilkinson, J.C.1
Wilkinson, A.S.2
Scott, F.L.3
Csomos, R.A.4
Salvesen, G.S.5
Duckett, C.S.6
-
125
-
-
33846964621
-
Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak
-
Willis S.N., Fletcher J.I., Kaufmann T., van Delft M.F., Chen L., Czabotar P.E., Ierino H., Lee E.F., Fairlie W.D., Bouillet P., Strasser A., Kluck R.M., Adams J.M., Huang D.C. Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak. Science 2007, 315:856-859.
-
(2007)
Science
, vol.315
, pp. 856-859
-
-
Willis, S.N.1
Fletcher, J.I.2
Kaufmann, T.3
van Delft, M.F.4
Chen, L.5
Czabotar, P.E.6
Ierino, H.7
Lee, E.F.8
Fairlie, W.D.9
Bouillet, P.10
Strasser, A.11
Kluck, R.M.12
Adams, J.M.13
Huang, D.C.14
-
126
-
-
0023224018
-
The role of lysosomal enzymes in killing of mammalian cells by the lysosomotropic detergent N-dodecylimidazole
-
Wilson P.D., Firestone R.A., Lenard J. The role of lysosomal enzymes in killing of mammalian cells by the lysosomotropic detergent N-dodecylimidazole. J. Cell Biol. 1987, 104:1223-1229.
-
(1987)
J. Cell Biol.
, vol.104
, pp. 1223-1229
-
-
Wilson, P.D.1
Firestone, R.A.2
Lenard, J.3
-
127
-
-
49349112331
-
Opa1-mediated cristae opening is Bax/Bak and BH3 dependent, required for apoptosis, and independent of Bak oligomerization
-
Yamaguchi R., Lartigue L., Perkins G., Scott R.T., Dixit A., Kushnareva Y., Kuwana T., Ellisman M.H., Newmeyer D.D. Opa1-mediated cristae opening is Bax/Bak and BH3 dependent, required for apoptosis, and independent of Bak oligomerization. Mol. Cell 2008, 31:557-569.
-
(2008)
Mol. Cell
, vol.31
, pp. 557-569
-
-
Yamaguchi, R.1
Lartigue, L.2
Perkins, G.3
Scott, R.T.4
Dixit, A.5
Kushnareva, Y.6
Kuwana, T.7
Ellisman, M.H.8
Newmeyer, D.D.9
-
128
-
-
70450222302
-
The role of lysosomal rupture in neuronal death
-
Yamashima T., Oikawa S. The role of lysosomal rupture in neuronal death. Prog. Neurobiol. 2009, 89:343-358.
-
(2009)
Prog. Neurobiol.
, vol.89
, pp. 343-358
-
-
Yamashima, T.1
Oikawa, S.2
-
129
-
-
33644657517
-
BID, a BH3-only multi-functional molecule, is at the cross road of life and death
-
Yin X.M. BID, a BH3-only multi-functional molecule, is at the cross road of life and death. Gene 2006, 369:7-19.
-
(2006)
Gene
, vol.369
, pp. 7-19
-
-
Yin, X.M.1
-
130
-
-
0033607006
-
BID-deficient mice are resistant to Fas-induced hepatocellular apoptosis
-
Yin X.M., Wang K., Gross A., Zhao Y., Zinkel S., Klocke B., Roth K.A., Korsmeyer S.J. BID-deficient mice are resistant to Fas-induced hepatocellular apoptosis. Nature 1999, 400:886-891.
-
(1999)
Nature
, vol.400
, pp. 886-891
-
-
Yin, X.M.1
Wang, K.2
Gross, A.3
Zhao, Y.4
Zinkel, S.5
Klocke, B.6
Roth, K.A.7
Korsmeyer, S.J.8
-
132
-
-
37549048249
-
The BCL-2 protein family: opposing activities that mediate cell death
-
Youle R.J., Strasser A. The BCL-2 protein family: opposing activities that mediate cell death. Nat. Rev. Mol. Cell Biol. 2008, 9:47-59.
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 47-59
-
-
Youle, R.J.1
Strasser, A.2
-
133
-
-
67349169961
-
Insights on a new path of pre-mitochondrial apoptosis regulation by a glycosaminoglycan mimetic
-
Yue X.L., Lehri S., Li P., Barbier-Chassefiere V., Petit E., Huang Q.F., Albanese P., Barritault D., Caruelle J.P., Papy-Garcia D., Morin C. Insights on a new path of pre-mitochondrial apoptosis regulation by a glycosaminoglycan mimetic. Cell Death Differ. 2009, 16:770-781.
-
(2009)
Cell Death Differ.
, vol.16
, pp. 770-781
-
-
Yue, X.L.1
Lehri, S.2
Li, P.3
Barbier-Chassefiere, V.4
Petit, E.5
Huang, Q.F.6
Albanese, P.7
Barritault, D.8
Caruelle, J.P.9
Papy-Garcia, D.10
Morin, C.11
-
134
-
-
77953121576
-
MTCH2/MIMP is a major facilitator of tBID recruitment to mitochondria
-
Zaltsman Y., Shachnai L., Yivgi-Ohana N., Schwarz M., Maryanovich M., Houtkooper R.H., Vaz F.M., De Leonardis F., Fiermonte G., Palmieri F., Gillissen B., Daniel P.T., Jimenez E., Walsh S., Koehler C.M., Roy S.S., Walter L., Hajnoczky G., Gross A. MTCH2/MIMP is a major facilitator of tBID recruitment to mitochondria. Nat. Cell Biol. 2010, 12:553-562.
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 553-562
-
-
Zaltsman, Y.1
Shachnai, L.2
Yivgi-Ohana, N.3
Schwarz, M.4
Maryanovich, M.5
Houtkooper, R.H.6
Vaz, F.M.7
De Leonardis, F.8
Fiermonte, G.9
Palmieri, F.10
Gillissen, B.11
Daniel, P.T.12
Jimenez, E.13
Walsh, S.14
Koehler, C.M.15
Roy, S.S.16
Walter, L.17
Hajnoczky, G.18
Gross, A.19
-
135
-
-
42549100331
-
Cystatin protease inhibitors and immune functions
-
Zavašnik-Bergant T. Cystatin protease inhibitors and immune functions. Front. Biosci. 2008, 13:4625-4637.
-
(2008)
Front. Biosci.
, vol.13
, pp. 4625-4637
-
-
Zavašnik-Bergant, T.1
-
136
-
-
0034711474
-
Protection against oxidant-mediated lysosomal rupture: a new anti-apoptotic activity of Bcl-2?
-
Zhao M., Eaton J.W., Brunk U.T. Protection against oxidant-mediated lysosomal rupture: a new anti-apoptotic activity of Bcl-2?. FEBS Lett. 2000, 485:104-108.
-
(2000)
FEBS Lett.
, vol.485
, pp. 104-108
-
-
Zhao, M.1
Eaton, J.W.2
Brunk, U.T.3
-
138
-
-
0141447370
-
Lysosomal enzymes promote mitochondrial oxidant production, cytochrome c release and apoptosis
-
Zhao M., Antunes F., Eaton J.W., Brunk U.T. Lysosomal enzymes promote mitochondrial oxidant production, cytochrome c release and apoptosis. Eur. J. Biochem. 2003, 270:3778-3786.
-
(2003)
Eur. J. Biochem.
, vol.270
, pp. 3778-3786
-
-
Zhao, M.1
Antunes, F.2
Eaton, J.W.3
Brunk, U.T.4
|