TNF-receptor I defective in internalization allows for cell death through activation of neutral sphingomyelinase

Experimental Cell Research

Volumn 312, Issue 11, 2006, Pages 2142-2153

  Neumeyer, Jens ^a   Hallas, Cora ^a   Merkel, Oliver ^b   Winoto Morbach, Supandi ^a   Jakob, Marten ^a   Thon, Lutz ^a   Adam, Dieter ^a   Schneider Brachert, Wulf ^b   Schütze, Stefan ^a  

^a UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^b UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

Apoptosis; Caspase; Cathepsin D; DISC; Sphingomyelinase; TNF RI

Indexed keywords

CASPASE 3; CASPASE 9; SPHINGOMYELIN PHOSPHODIESTERASE; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR 1; CASP3 PROTEIN, MOUSE; CASP9 PROTEIN, MOUSE; CASPASE; CERAMIDE; DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEIN; DEDD PROTEIN, MOUSE; DNA BINDING PROTEIN; NSMAF PROTEIN, MOUSE; SIGNAL PEPTIDE; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 2;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL LINE; CELL SURFACE; CELL TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE DELETION; GENETIC TRANSFECTION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; ANIMAL; BIOLOGICAL MODEL; CELL CULTURE; CHEMISTRY; DRUG EFFECT; FIBROBLAST; GENETICS; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; PROTEIN MOTIF; PROTEIN TERTIARY STRUCTURE; PROTEIN TRANSPORT;

AMINO ACID MOTIFS; ANIMALS; CASPASE 3; CASPASE 9; CASPASES; CELL DEATH; CELLS, CULTURED; CERAMIDES; DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS; DNA-BINDING PROTEINS; ENZYME ACTIVATION; FIBROBLASTS; GENE DELETION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, KNOCKOUT; MODELS, BIOLOGICAL; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE II; RNA, SMALL INTERFERING; SPHINGOMYELIN PHOSPHODIESTERASE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33746690768     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2006.03.014     Document Type: Article

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