Cysteine cathepsins trigger caspase-dependent cell death through cleavage of bid and antiapoptotic Bcl-2 homologues

Journal of Biological Chemistry

Volumn 283, Issue 27, 2008, Pages 19140-19150

  Droga Mazovec, Gabriela ^a   Bojič, Lea ^a   Petelin, Ana ^a   Ivanova, Saška ^a   Romih, Rok ^b   Repnik, Urška ^a   Salvesen, Guy S ^c   Stoka, Veronika ^a   Turk, Vito ^a   Turk, Boris ^a  

^a JO EF STEFAN INSTITUTE   (Slovenia)

^b UNIVERSITY OF LJUBLJANA   (Slovenia)

^c BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; DEGRADATION; KETONES;

ANTIAPOPTOTIC; APOPTOSIS; BENZYLOXYCARBONYL; CASPASE; CELLULAR MODELS; CYSTEINE PROTEASES; FAMILY MEMBERS; IN VITRO EXPERIMENTS; INHIBITOR OF APOPTOSIS; LYSOSOMAL MEMBRANES; MITOCHONDRIAL DAMAGES; MITOCHONDRIAL PATHWAYS;

CELL DEATH;

ACTIN; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE; CATHEPSIN; CATHEPSIN B; CATHEPSIN H; CATHEPSIN K; CATHEPSIN L; CATHEPSIN S; CYSTEINE; INHIBITOR OF APOPTOSIS PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PAPAIN; PROTEIN BAK; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN BID; PROTEIN BIMEL; PROTEIN MCL 1; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS; APOPTOSIS REGULATORY PROTEIN; BAK1 PROTEIN, HUMAN; BCL 2 LIKE PROTEIN 11; BCL-2-LIKE PROTEIN 11; BCL2L1 PROTEIN, HUMAN; BID PROTEIN, HUMAN; MEMBRANE PROTEIN; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; ONCOPROTEIN; PROTEIN BCL X; PROTEINASE INHIBITOR; XIAP PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; LYSOSOME; MEMBRANE DAMAGE; MITOCHONDRIAL MEMBRANE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; CELL STRAIN CACO 2; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; METABOLISM; MITOCHONDRION; PHYSIOLOGY;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-X PROTEIN; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CACO-2 CELLS; CATHEPSINS; HUMANS; LYSOSOMES; MEMBRANE PROTEINS; MITOCHONDRIA; PROTEASE INHIBITORS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 49649123891     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M802513200     Document Type: Article

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