메뉴 건너뛰기




Volumn 25, Issue 4, 1997, Pages 958-963

Ceramide induces hepatocyte cell death through disruption of mitochondrial function in the rat

Author keywords

[No Author keywords available]

Indexed keywords

CERAMIDE;

EID: 0031005956     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.510250428     Document Type: Article
Times cited : (156)

References (24)
  • 1
    • 0028795316 scopus 로고
    • Liver cell necrosis: Cellular mechanisms and clinical implications
    • Rosser B, Gores G. Liver cell necrosis: cellular mechanisms and clinical implications. Gastroenterology 1995;108:252-275.
    • (1995) Gastroenterology , vol.108 , pp. 252-275
    • Rosser, B.1    Gores, G.2
  • 2
    • 0029925907 scopus 로고    scopus 로고
    • A cascade of degradative hydrolase activity contributes to hepatocyte necrosis during anoxia
    • Arora AS, de Groen PC, Emori Y, Gores GJ. A cascade of degradative hydrolase activity contributes to hepatocyte necrosis during anoxia. Am J Physiol 1996;270:G238-G245.
    • (1996) Am J Physiol , vol.270
    • Arora, A.S.1    De Groen, P.C.2    Emori, Y.3    Gores, G.J.4
  • 3
    • 0027762512 scopus 로고
    • Sphingolipid breakdown products: Anti-proliferative and tumor-supressor lipids
    • Hannun Y, Linardic CM. Sphingolipid breakdown products: anti-proliferative and tumor-supressor lipids. Biochim Biophys Acta 1993;1154:223-236.
    • (1993) Biochim Biophys Acta , vol.1154 , pp. 223-236
    • Hannun, Y.1    Linardic, C.M.2
  • 4
    • 0028855405 scopus 로고
    • Ceramide: An intracellular signal for apoptosis
    • Hannun Y, Obeid LM. Ceramide: an intracellular signal for apoptosis. TIBS 1995;20:73-77.
    • (1995) TIBS , vol.20 , pp. 73-77
    • Hannun, Y.1    Obeid, L.M.2
  • 5
    • 0029055676 scopus 로고
    • Ceramide: A stress signal and mediator of growth suppression and apoptosis
    • Obeid LM, Hannun YA. Ceramide: a stress signal and mediator of growth suppression and apoptosis. J Cell Biochem 1995;58:191-198.
    • (1995) J Cell Biochem , vol.58 , pp. 191-198
    • Obeid, L.M.1    Hannun, Y.A.2
  • 6
    • 0029023368 scopus 로고
    • Does endotoxin stimulate cells by mimicking ceramide?
    • Wright SD, Kolesnick RN. Does endotoxin stimulate cells by mimicking ceramide? Immunology Today 1995;16:297-305.
    • (1995) Immunology Today , vol.16 , pp. 297-305
    • Wright, S.D.1    Kolesnick, R.N.2
  • 7
    • 0029056908 scopus 로고
    • Sphingosine: A mediator of acute renal tubular injury and subsequent cytoresistance
    • Iwata M, Herrington J, Zager RA. Sphingosine: a mediator of acute renal tubular injury and subsequent cytoresistance. Proc Natl Acad Sci U S A 1995;92:8970-8974.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 8970-8974
    • Iwata, M.1    Herrington, J.2    Zager, R.A.3
  • 8
    • 0030021473 scopus 로고    scopus 로고
    • Induction of the mitochondrial permeability transition by protease activity in rats: A mechanism of hepatocyte necrosis
    • Aguilar H, Botla R, Arora AS, Bronk SF, Gores GJ. Induction of the mitochondrial permeability transition by protease activity in rats: a mechanism of hepatocyte necrosis. Gastroenterology 1996;110:558-566.
    • (1996) Gastroenterology , vol.110 , pp. 558-566
    • Aguilar, H.1    Botla, R.2    Arora, A.S.3    Bronk, S.F.4    Gores, G.J.5
  • 9
    • 0028053663 scopus 로고
    • Recent progress on regulation of the mitochondrial permeability transition pore; a cyclosporin sensitive pore in the inner mitochondrial membrane
    • Bernardi P, Broekmeier KM, Pfeiffer DR. Recent progress on regulation of the mitochondrial permeability transition pore; a cyclosporin sensitive pore in the inner mitochondrial membrane. J Bioenerg Biomem 1994;26:509-517.
    • (1994) J Bioenerg Biomem , vol.26 , pp. 509-517
    • Bernardi, P.1    Broekmeier, K.M.2    Pfeiffer, D.R.3
  • 10
    • 0028816461 scopus 로고
    • Ursodeoxycholic acid (UDCA) inhibits the mitochondrial membrane permeability transition induced by glycochenodeoxycholate: A mechanism of UDCA protection
    • Botla R, Spivey JR, Aguilar H, Bronk SF, Gores GJ. Ursodeoxycholic acid (UDCA) inhibits the mitochondrial membrane permeability transition induced by glycochenodeoxycholate: a mechanism of UDCA protection. J Pharm Exp Ther 1995;272:930-938.
    • (1995) J Pharm Exp Ther , vol.272 , pp. 930-938
    • Botla, R.1    Spivey, J.R.2    Aguilar, H.3    Bronk, S.F.4    Gores, G.J.5
  • 11
    • 0027156357 scopus 로고
    • Cyclosporin A and carnitine prevent the anoxic death of cultured hepatocytes by inhibiting the mitochondrial permeability transition
    • Pastrorino JG, Snyder JW, Serroni A, Hoek JB, Farber JJ. Cyclosporin A and carnitine prevent the anoxic death of cultured hepatocytes by inhibiting the mitochondrial permeability transition. J Biol Chem 1993;268: 13791-13798.
    • (1993) J Biol Chem , vol.268 , pp. 13791-13798
    • Pastrorino, J.G.1    Snyder, J.W.2    Serroni, A.3    Hoek, J.B.4    Farber, J.J.5
  • 12
    • 0027229472 scopus 로고
    • PH dependent non-lysosomal proteolysis contributes to lethal anoxic injury of rat hepatocytes
    • Bronk SF, Gores GJ. pH dependent non-lysosomal proteolysis contributes to lethal anoxic injury of rat hepatocytes. Am J Physiol 1993;264:G744-G751.
    • (1993) Am J Physiol , vol.264
    • Bronk, S.F.1    Gores, G.J.2
  • 13
    • 0028283104 scopus 로고
    • Mitochondrial dysfunction during anoxia/ reoxygenation injury of liver sinusoidal endothelial cells
    • Fujii Y, Johnson ME, Gores GJ. Mitochondrial dysfunction during anoxia/ reoxygenation injury of liver sinusoidal endothelial cells. HEPATOLOGY 1994;20:177-185.
    • (1994) Hepatology , vol.20 , pp. 177-185
    • Fujii, Y.1    Johnson, M.E.2    Gores, G.J.3
  • 14
    • 0026583939 scopus 로고
    • Ruthenium red delays the onset of cell death during oxidative stress of rat hepatocytes
    • Groskreutz JL, Bronk SF, Gores GJ. Ruthenium red delays the onset of cell death during oxidative stress of rat hepatocytes. Gastroenterology 1992;102:1030-1038.
    • (1992) Gastroenterology , vol.102 , pp. 1030-1038
    • Groskreutz, J.L.1    Bronk, S.F.2    Gores, G.J.3
  • 15
    • 0028135420 scopus 로고
    • Increases of intracellular magnesium promote glycodeoxycholate-induced apoptosis in rat hepatocytes
    • Patel TC, Bronk SF, Gores GJ. Increases of intracellular magnesium promote glycodeoxycholate-induced apoptosis in rat hepatocytes. J Clin Invest 1994;94:2183-2192.
    • (1994) J Clin Invest , vol.94 , pp. 2183-2192
    • Patel, T.C.1    Bronk, S.F.2    Gores, G.J.3
  • 17
    • 0029012444 scopus 로고
    • Apoptosis in hepatobiliary disease
    • Patel TC, Gores GJ. Apoptosis in hepatobiliary disease. HEPATOLOGY 1995; 21:1725-1741.
    • (1995) Hepatology , vol.21 , pp. 1725-1741
    • Patel, T.C.1    Gores, G.J.2
  • 18
    • 0028122397 scopus 로고
    • Role of ceramide-activated protein phosphatase in ceramide-mediated signal transduction
    • Wolff RA, Dobrowsky RT, Bielawska A, Obeid LM, Hannun YA. Role of ceramide-activated protein phosphatase in ceramide-mediated signal transduction. J Biol Chem 1994;269:19605-19609.
    • (1994) J Biol Chem , vol.269 , pp. 19605-19609
    • Wolff, R.A.1    Dobrowsky, R.T.2    Bielawska, A.3    Obeid, L.M.4    Hannun, Y.A.5
  • 19
    • 0007712633 scopus 로고
    • Sphingolipid metabolism in cultured fibroblasts: Microscopic and biochemical studies employing a fluorescent ceramide analogue
    • Lipsky NG, Pagano RE. Sphingolipid metabolism in cultured fibroblasts: Microscopic and biochemical studies employing a fluorescent ceramide analogue. Proc Natl Acad Sci U S A 1983;80:2608-2612.
    • (1983) Proc Natl Acad Sci U S A , vol.80 , pp. 2608-2612
    • Lipsky, N.G.1    Pagano, R.E.2
  • 20
    • 0028923778 scopus 로고
    • Contribution of the mitochondrial permeability transition to lethal injury after exposure of hepatocytes to t-butylhydroperoxide
    • Nieminen A-L, Saylor AK, Tesfai SA, Herman B, Lemasters JJ. Contribution of the mitochondrial permeability transition to lethal injury after exposure of hepatocytes to t-butylhydroperoxide. Biochem J 1995;307:99106.
    • (1995) Biochem J , vol.307 , pp. 99106
    • Nieminen, A.-L.1    Saylor, A.K.2    Tesfai, S.A.3    Herman, B.4    Lemasters, J.J.5
  • 21
    • 0027413499 scopus 로고
    • The long chain sphingoid base of sphingolipids is acylated at the cytosolic surface of the endoplasmic reticulum in rat liver
    • Hirschberg K, Rodger J, Futerman AH. The long chain sphingoid base of sphingolipids is acylated at the cytosolic surface of the endoplasmic reticulum in rat liver. Biochem J 1993;290:751-757.
    • (1993) Biochem J , vol.290 , pp. 751-757
    • Hirschberg, K.1    Rodger, J.2    Futerman, A.H.3
  • 22
    • 0026712872 scopus 로고
    • Subcellular localization and membrane topology of serine palmitoyltransferase, 3-dehydrosphinganine reductase, and sphinganine N-acyltransferase in mouse liver
    • Mandon EC, Ehses I, Rother J, van Echten G, Sandhoff K. Subcellular localization and membrane topology of serine palmitoyltransferase, 3-dehydrosphinganine reductase, and sphinganine N-acyltransferase in mouse liver. J Biol Chem 1992;267:11144-11148.
    • (1992) J Biol Chem , vol.267 , pp. 11144-11148
    • Mandon, E.C.1    Ehses, I.2    Rother, J.3    Van Echten, G.4    Sandhoff, K.5
  • 23
    • 0030060075 scopus 로고    scopus 로고
    • Requirement of an ICE-like protease for induction of apoptosis and ceramide generation by REAPER
    • Pronk GJ, Ramer K, Amiri P, Williams LT. Requirement of an ICE-like protease for induction of apoptosis and ceramide generation by REAPER. Science 1996;271:808-810.
    • (1996) Science , vol.271 , pp. 808-810
    • Pronk, G.J.1    Ramer, K.2    Amiri, P.3    Williams, L.T.4
  • 24
    • 0029101644 scopus 로고
    • Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death
    • Zamzani N, Marchetti P, Castedo M, Decaudin D, Macho A, Hirsch T, Susin SA, et al. Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death. J Exp Med 1995;182:367-377.
    • (1995) J Exp Med , vol.182 , pp. 367-377
    • Zamzani, N.1    Marchetti, P.2    Castedo, M.3    Decaudin, D.4    Macho, A.5    Hirsch, T.6    Susin, S.A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.