The Fas-FADD death domain complex structure unravels signalling by receptor clustering

Nature

Volumn 457, Issue 7232, 2009, Pages 1019-1022

  Scott, Fiona L ^a,d   Stec, Boguslaw ^a   Pop, Cristina ^a   Dobaczewska, Małgorzata K ^a   Lee, Jeongeun J ^a   Monosov, Edward ^a   Robinson, Howard ^b   Salvesen, Guy S ^a   Schwarzenbacher, Robert ^c   Riedl, Stefan J ^a  

^a BURNHAM INSTITUTE   (United States)

^b BROOKHAVEN NATIONAL LABORATORY   (United States)

^c UNIVERSITY OF SALZBURG   (Austria)

^d Apoptos Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; OLIGOMER; TETRAMER;

HOMINID; MODEL; POLYMERIZATION; PROTEIN;

APOPTOSIS; ARTICLE; BINDING SITE; COMPLEX FORMATION; CRYSTAL STRUCTURE; MOLECULAR MODEL; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION;

ANTIGENS, CD95; CRYSTALLOGRAPHY, X-RAY; DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; HUMANS; MODELS, MOLECULAR; MULTIPROTEIN COMPLEXES; RECEPTOR AGGREGATION; SIGNAL TRANSDUCTION;

EID: 60549106191     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature07606     Document Type: Article

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