-
1
-
-
33645526144
-
Cancer statistics, 2006
-
Jemal A., Siegel R., Ward E., Murray T., Xu J., Smigal C., et al. Cancer statistics, 2006. CA Cancer J Clin 2006, 56(2):106-130.
-
(2006)
CA Cancer J Clin
, vol.56
, Issue.2
, pp. 106-130
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Murray, T.4
Xu, J.5
Smigal, C.6
-
2
-
-
33846457870
-
Cancer statistics, 2007
-
Jemal A., Siegel R., Ward E., Murray T., Xu J., Thun M.J. Cancer statistics, 2007. CA Cancer J Clin 2007, 57(1):43-66.
-
(2007)
CA Cancer J Clin
, vol.57
, Issue.1
, pp. 43-66
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Murray, T.4
Xu, J.5
Thun, M.J.6
-
3
-
-
41349099104
-
Cancer statistics, 2008
-
Jemal A., Siegel R., Ward E., Hao Y., Xu J., Murray T., et al. Cancer statistics, 2008. CA Cancer J Clin 2008, 58(2):71-96.
-
(2008)
CA Cancer J Clin
, vol.58
, Issue.2
, pp. 71-96
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Murray, T.6
-
4
-
-
67650874081
-
Cancer statistics, 2009
-
Jemal A., Siegel R., Ward E., Hao Y., Xu J., Thun M.J. Cancer statistics, 2009. CA Cancer J Clin 2009, 59(4):225-249.
-
(2009)
CA Cancer J Clin
, vol.59
, Issue.4
, pp. 225-249
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Thun, M.J.6
-
5
-
-
0017809827
-
The multistage theory of carcinogenesis and the age distribution of cancer in man
-
Moolgavkar S.H. The multistage theory of carcinogenesis and the age distribution of cancer in man. J Natl Cancer Inst 1978, 61(1):49-52.
-
(1978)
J Natl Cancer Inst
, vol.61
, Issue.1
, pp. 49-52
-
-
Moolgavkar, S.H.1
-
6
-
-
0036637235
-
Chemoprevention: an essential approach to controlling cancer
-
Sporn M.B., Suh N. Chemoprevention: an essential approach to controlling cancer. Nat Rev Cancer 2002, 2(7):537-543.
-
(2002)
Nat Rev Cancer
, vol.2
, Issue.7
, pp. 537-543
-
-
Sporn, M.B.1
Suh, N.2
-
7
-
-
27644477094
-
Cancer chemoprevention: scientific promise, clinical uncertainty
-
Sporn M.B., Liby K.T. Cancer chemoprevention: scientific promise, clinical uncertainty. Nat Clin Pract Oncol 2005, 2(10):518-525.
-
(2005)
Nat Clin Pract Oncol
, vol.2
, Issue.10
, pp. 518-525
-
-
Sporn, M.B.1
Liby, K.T.2
-
8
-
-
44649111827
-
Cancer chemoprevention: a radical perspective
-
Hail N., Cortes M., Drake E.N., Spallholz J.E. Cancer chemoprevention: a radical perspective. Free Radic Biol Med 2008, 45(2):97-110.
-
(2008)
Free Radic Biol Med
, vol.45
, Issue.2
, pp. 97-110
-
-
Hail, N.1
Cortes, M.2
Drake, E.N.3
Spallholz, J.E.4
-
9
-
-
0021934758
-
Chemoprevention of cancer
-
Wattenberg L.W. Chemoprevention of cancer. Cancer Res 1985, 45(1):1-8.
-
(1985)
Cancer Res
, vol.45
, Issue.1
, pp. 1-8
-
-
Wattenberg, L.W.1
-
10
-
-
0034653353
-
Blocking and suppressing mechanisms of chemoprevention by dietary constituents
-
Manson M.M., Gescher A., Hudson E.A., Plummer S.M., Squires M.S., Prigent A. Blocking and suppressing mechanisms of chemoprevention by dietary constituents. Toxicol Lett 2000, 112-113:499-505.
-
(2000)
Toxicol Lett
, pp. 499-505
-
-
Manson, M.M.1
Gescher, A.2
Hudson, E.A.3
Plummer, S.M.4
Squires, M.S.5
Prigent, A.6
-
11
-
-
0142166328
-
Cancer chemoprevention with dietary phytochemicals
-
Surh Y.J. Cancer chemoprevention with dietary phytochemicals. Nat Rev Cancer 2003, 3(10):768-780.
-
(2003)
Nat Rev Cancer
, vol.3
, Issue.10
, pp. 768-780
-
-
Surh, Y.J.1
-
12
-
-
19444379739
-
Nrf2 as a novel molecular target for chemoprevention
-
Lee J.S., Surh Y.J. Nrf2 as a novel molecular target for chemoprevention. Cancer Lett 2005, 224(2):171-184.
-
(2005)
Cancer Lett
, vol.224
, Issue.2
, pp. 171-184
-
-
Lee, J.S.1
Surh, Y.J.2
-
13
-
-
0028061444
-
Isolation of NF-E2-related factor 2(Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region
-
Moi P., Chan K., Asunis I., Cao A., Kan Y.W. Isolation of NF-E2-related factor 2(Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region. Proc Natl Acad Sci USA 1994, 91(21):9926-9930.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, Issue.21
, pp. 9926-9930
-
-
Moi, P.1
Chan, K.2
Asunis, I.3
Cao, A.4
Kan, Y.W.5
-
14
-
-
0037821802
-
Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression
-
McMahon M., Itoh K., Yamamoto M., Hayes J.D. Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression. J Biol Chem 2003, 278(24):21592-21600.
-
(2003)
J Biol Chem
, vol.278
, Issue.24
, pp. 21592-21600
-
-
McMahon, M.1
Itoh, K.2
Yamamoto, M.3
Hayes, J.D.4
-
15
-
-
0032953192
-
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
-
Itoh K., Wakabayashi N., Katoh Y., Ishii T., Igarashi K., Engel J.D., et al. Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev 1999, 13(1):76-86.
-
(1999)
Genes Dev
, vol.13
, Issue.1
, pp. 76-86
-
-
Itoh, K.1
Wakabayashi, N.2
Katoh, Y.3
Ishii, T.4
Igarashi, K.5
Engel, J.D.6
-
16
-
-
10044228504
-
Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex
-
Zhang D.D., Lo S.C., Cross J.V., Templeton D.J., Hannink M. Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex. Mol Cell Biol 2004, 24(24):10941-10953.
-
(2004)
Mol Cell Biol
, vol.24
, Issue.24
, pp. 10941-10953
-
-
Zhang, D.D.1
Lo, S.C.2
Cross, J.V.3
Templeton, D.J.4
Hannink, M.5
-
17
-
-
28544450507
-
The carboxy-terminal Neh3 domain of Nrf2 is required for transcriptional activation
-
Nioi P., Nguyen T., Sherratt P.J., Pickett C.B. The carboxy-terminal Neh3 domain of Nrf2 is required for transcriptional activation. Mol Cell Biol 2005, 25(24):10895-10906.
-
(2005)
Mol Cell Biol
, vol.25
, Issue.24
, pp. 10895-10906
-
-
Nioi, P.1
Nguyen, T.2
Sherratt, P.J.3
Pickett, C.B.4
-
18
-
-
0034752461
-
Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription
-
Katoh Y., Itoh K., Yoshida E., Miyagishi M., Fukamizu A., Yamamoto M. Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription. Genes Cells 2001, 6(10):857-868.
-
(2001)
Genes Cells
, vol.6
, Issue.10
, pp. 857-868
-
-
Katoh, Y.1
Itoh, K.2
Yoshida, E.3
Miyagishi, M.4
Fukamizu, A.5
Yamamoto, M.6
-
19
-
-
4544294365
-
The keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase
-
Cullinan S., Gordan J., Jin J., Harper J., Diehl J. The keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase. Mol Cell Biol 2004, 24(19):8477-8486.
-
(2004)
Mol Cell Biol
, vol.24
, Issue.19
, pp. 8477-8486
-
-
Cullinan, S.1
Gordan, J.2
Jin, J.3
Harper, J.4
Diehl, J.5
-
20
-
-
11144264663
-
BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the cullin 3-Roc1 ligase
-
Furukawa M., Xiong Y. BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the cullin 3-Roc1 ligase. Mol Cell Biol 2005, 25(1):162-171.
-
(2005)
Mol Cell Biol
, vol.25
, Issue.1
, pp. 162-171
-
-
Furukawa, M.1
Xiong, Y.2
-
22
-
-
0037183998
-
The Keap1 BTB/POZ dimerization function is required to sequester Nrf2 in cytoplasm
-
Zipper L.M., Mulcahy R.T. The Keap1 BTB/POZ dimerization function is required to sequester Nrf2 in cytoplasm. J Biol Chem 2002, 277(39):36544-36552.
-
(2002)
J Biol Chem
, vol.277
, Issue.39
, pp. 36544-36552
-
-
Zipper, L.M.1
Mulcahy, R.T.2
-
23
-
-
3543008924
-
Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2
-
Kobayashi A., Kang M.I., Okawa H., Ohtsuji M., Zenke Y., Chiba T., et al. Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2. Mol Cell Biol 2004, 24(16):7130-7139.
-
(2004)
Mol Cell Biol
, vol.24
, Issue.16
, pp. 7130-7139
-
-
Kobayashi, A.1
Kang, M.I.2
Okawa, H.3
Ohtsuji, M.4
Zenke, Y.5
Chiba, T.6
-
24
-
-
0036668466
-
Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system
-
Kobayashi M., Itoh K., Suzuki T., Osanai H., Nishikawa K., Katoh Y., et al. Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system. Genes Cells 2002, 7(8):807-820.
-
(2002)
Genes Cells
, vol.7
, Issue.8
, pp. 807-820
-
-
Kobayashi, M.1
Itoh, K.2
Suzuki, T.3
Osanai, H.4
Nishikawa, K.5
Katoh, Y.6
-
25
-
-
33747728194
-
Dimerization of substrate adaptors can facilitate Cullin-mediated ubiquitylation of proteins by a "Tethering" mechanism: a two-site interaction model for the Nrf2-Keap1 complex
-
McMahon M., Thomas N., Itoh K., Yamamoto M., Hayes J.D. Dimerization of substrate adaptors can facilitate Cullin-mediated ubiquitylation of proteins by a "Tethering" mechanism: a two-site interaction model for the Nrf2-Keap1 complex. J Biol Chem 2006, 281(34):24756-24768.
-
(2006)
J Biol Chem
, vol.281
, Issue.34
, pp. 24756-24768
-
-
McMahon, M.1
Thomas, N.2
Itoh, K.3
Yamamoto, M.4
Hayes, J.D.5
-
26
-
-
33344463325
-
Keap1 recruits Neh2 through binding to ETGE and DLG motifs: characterization of the two-site molecular recognition model
-
Tong K.I., Katoh Y., Kusunoki H., Itoh K., Tanaka T., Yamamoto M. Keap1 recruits Neh2 through binding to ETGE and DLG motifs: characterization of the two-site molecular recognition model. Mol Cell Biol 2006, 26(8):2887-2900.
-
(2006)
Mol Cell Biol
, vol.26
, Issue.8
, pp. 2887-2900
-
-
Tong, K.I.1
Katoh, Y.2
Kusunoki, H.3
Itoh, K.4
Tanaka, T.5
Yamamoto, M.6
-
27
-
-
33747606306
-
Structure of the Keap1: Nrf2 interface provides mechanistic insight into Nrf2 signaling
-
Lo S.C., Li X., Henzl M.T., Beamer L.J., Hannink M. Structure of the Keap1: Nrf2 interface provides mechanistic insight into Nrf2 signaling. EMBO J 2006, 25(15):3605-3617.
-
(2006)
EMBO J
, vol.25
, Issue.15
, pp. 3605-3617
-
-
Lo, S.C.1
Li, X.2
Henzl, M.T.3
Beamer, L.J.4
Hannink, M.5
-
28
-
-
0031577292
-
An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements
-
Itoh K., Chiba T., Takahashi S., Ishii T., Igarashi K., Katoh Y., et al. An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem Biophys Res Commun 1997, 236(2):313-322.
-
(1997)
Biochem Biophys Res Commun
, vol.236
, Issue.2
, pp. 313-322
-
-
Itoh, K.1
Chiba, T.2
Takahashi, S.3
Ishii, T.4
Igarashi, K.5
Katoh, Y.6
-
29
-
-
0037015035
-
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
-
Dinkova-Kostova A.T., Holtzclaw W.D., Cole R.N., Itoh K., Wakabayashi N., Katoh Y., et al. Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants. Proc Natl Acad Sci USA 2002, 99(18):11908-11913.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.18
, pp. 11908-11913
-
-
Dinkova-Kostova, A.T.1
Holtzclaw, W.D.2
Cole, R.N.3
Itoh, K.4
Wakabayashi, N.5
Katoh, Y.6
-
30
-
-
33344469643
-
Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1
-
Kobayashi A., Kang M.I., Watai Y., Tong K.I., Shibata T., Uchida K., et al. Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1. Mol Cell Biol 2006, 26(1):221-229.
-
(2006)
Mol Cell Biol
, vol.26
, Issue.1
, pp. 221-229
-
-
Kobayashi, A.1
Kang, M.I.2
Watai, Y.3
Tong, K.I.4
Shibata, T.5
Uchida, K.6
-
31
-
-
0242580049
-
Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress
-
Zhang D.D., Hannink M. Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress. Mol Cell Biol 2003, 23(22):8137-8151.
-
(2003)
Mol Cell Biol
, vol.23
, Issue.22
, pp. 8137-8151
-
-
Zhang, D.D.1
Hannink, M.2
-
32
-
-
24044466764
-
Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway
-
Zhang D.D., Lo S.C., Sun Z., Habib G.M., Lieberman M.W., Hannink M. Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway. J Biol Chem 2005, 280(34):30091-30099.
-
(2005)
J Biol Chem
, vol.280
, Issue.34
, pp. 30091-30099
-
-
Zhang, D.D.1
Lo, S.C.2
Sun, Z.3
Habib, G.M.4
Lieberman, M.W.5
Hannink, M.6
-
33
-
-
27844612530
-
Nrf2 as a target for cancer chemoprevention
-
Yu X., Kensler T. Nrf2 as a target for cancer chemoprevention. Mutat Res 2005, 591(1-2):93-102.
-
(2005)
Mutat Res
, vol.591
, Issue.1-2
, pp. 93-102
-
-
Yu, X.1
Kensler, T.2
-
34
-
-
36349020163
-
Sites of alkylation of human Keap1 by natural chemoprevention agents
-
Luo Y., Eggler A.L., Liu D., Liu G., Mesecar A.D., van Breemen R.B. Sites of alkylation of human Keap1 by natural chemoprevention agents. J Am Soc Mass Spectrom 2007, 18(12):2226-2232.
-
(2007)
J Am Soc Mass Spectrom
, vol.18
, Issue.12
, pp. 2226-2232
-
-
Luo, Y.1
Eggler, A.L.2
Liu, D.3
Liu, G.4
Mesecar, A.D.5
van Breemen, R.B.6
-
35
-
-
36349019109
-
Identification of the highly reactive cysteine 151 in the chemopreventive agent-sensor Keap1 protein is method-dependent
-
Eggler A.L., Luo Y., van Breemen R.B., Mesecar A.D. Identification of the highly reactive cysteine 151 in the chemopreventive agent-sensor Keap1 protein is method-dependent. Chem Res Toxicol 2007, 20(12):1878-1884.
-
(2007)
Chem Res Toxicol
, vol.20
, Issue.12
, pp. 1878-1884
-
-
Eggler, A.L.1
Luo, Y.2
van Breemen, R.B.3
Mesecar, A.D.4
-
36
-
-
22544464124
-
Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2
-
Eggler A.L., Liu G., Pezzuto J.M., van Breemen R.B., Mesecar A.D. Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2. Proc Natl Acad Sci USA 2005, 102(29):10070-10075.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.29
, pp. 10070-10075
-
-
Eggler, A.L.1
Liu, G.2
Pezzuto, J.M.3
van Breemen, R.B.4
Mesecar, A.D.5
-
37
-
-
1242296811
-
Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers
-
Wakabayashi N., Dinkova-Kostova A.T., Holtzclaw W.D., Kang M.I., Kobayashi A., Yamamoto M., et al. Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers. Proc Natl Acad Sci USA 2004, 101(7):2040-2045.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.7
, pp. 2040-2045
-
-
Wakabayashi, N.1
Dinkova-Kostova, A.T.2
Holtzclaw, W.D.3
Kang, M.I.4
Kobayashi, A.5
Yamamoto, M.6
-
38
-
-
47749116455
-
Phosphorylation and dephosphorylation of tyrosine 141 regulate stability and degradation of INrf2: a novel mechanism in Nrf2 activation
-
Jain A.K., Mahajan S., Jaiswal A.K. Phosphorylation and dephosphorylation of tyrosine 141 regulate stability and degradation of INrf2: a novel mechanism in Nrf2 activation. J Biol Chem 2008, 283(25):17712-17720.
-
(2008)
J Biol Chem
, vol.283
, Issue.25
, pp. 17712-17720
-
-
Jain, A.K.1
Mahajan, S.2
Jaiswal, A.K.3
-
39
-
-
0037044791
-
Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription
-
Huang H.C., Nguyen T., Pickett C.B. Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription. J Biol Chem 2002, 277(45):42769-42774.
-
(2002)
J Biol Chem
, vol.277
, Issue.45
, pp. 42769-42774
-
-
Huang, H.C.1
Nguyen, T.2
Pickett, C.B.3
-
40
-
-
0242666198
-
Phosphorylation of Nrf2 at Ser 40 by protein kinase C in response to antioxidants leads to the release of Nrf2 from INrf2, but is not required for Nrf2 stabilization/accumulation in the nucleus and transcriptional activation of antioxidant response element-mediated NAD(P)H:quinone oxidoreductase-1 gene expression
-
Bloom D.A., Jaiswal A.K. Phosphorylation of Nrf2 at Ser 40 by protein kinase C in response to antioxidants leads to the release of Nrf2 from INrf2, but is not required for Nrf2 stabilization/accumulation in the nucleus and transcriptional activation of antioxidant response element-mediated NAD(P)H:quinone oxidoreductase-1 gene expression. J Biol Chem 2003, 278(45):44675-44682.
-
(2003)
J Biol Chem
, vol.278
, Issue.45
, pp. 44675-44682
-
-
Bloom, D.A.1
Jaiswal, A.K.2
-
41
-
-
0036436025
-
Peroxynitrite activates NF-E2-related factor 2/antioxidant response element through the pathway of phosphatidylinositol 3-kinase: The role of nitric oxide synthase in rat glutathione S-transferase A2 induction
-
Kang K.W., Choi S.H., Kim S.G. Peroxynitrite activates NF-E2-related factor 2/antioxidant response element through the pathway of phosphatidylinositol 3-kinase: The role of nitric oxide synthase in rat glutathione S-transferase A2 induction. Nitric Oxide 2002, 7(4):244-253.
-
(2002)
Nitric Oxide
, vol.7
, Issue.4
, pp. 244-253
-
-
Kang, K.W.1
Choi, S.H.2
Kim, S.G.3
-
42
-
-
0034704079
-
Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism
-
Yu R., Chen C., Mo Y.Y., Hebbar V., Owuor E.D., Tan T.H., et al. Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism. J Biol Chem 2000, 275(51):39907-39913.
-
(2000)
J Biol Chem
, vol.275
, Issue.51
, pp. 39907-39913
-
-
Yu, R.1
Chen, C.2
Mo, Y.Y.3
Hebbar, V.4
Owuor, E.D.5
Tan, T.H.6
-
43
-
-
2442542312
-
PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress
-
Cullinan S.B., Diehl J.A. PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress. J Biol Chem 2004, 279(19):20108-20117.
-
(2004)
J Biol Chem
, vol.279
, Issue.19
, pp. 20108-20117
-
-
Cullinan, S.B.1
Diehl, J.A.2
-
44
-
-
0141752795
-
Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival
-
Cullinan S.B., Zhang D., Hannink M., Arvisais E., Kaufman R.J., Diehl J.A. Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival. Mol Cell Biol 2003, 23(20):7198-7209.
-
(2003)
Mol Cell Biol
, vol.23
, Issue.20
, pp. 7198-7209
-
-
Cullinan, S.B.1
Zhang, D.2
Hannink, M.3
Arvisais, E.4
Kaufman, R.J.5
Diehl, J.A.6
-
45
-
-
34248593492
-
Molecular mechanism of human Nrf2 activation and degradation: role of sequential phosphorylation by protein kinase CK2
-
Pi J., Bai Y., Reece J.M., Williams J., Liu D., Freeman M.L., et al. Molecular mechanism of human Nrf2 activation and degradation: role of sequential phosphorylation by protein kinase CK2. Free Radic Biol Med 2007, 42(12):1797-1806.
-
(2007)
Free Radic Biol Med
, vol.42
, Issue.12
, pp. 1797-1806
-
-
Pi, J.1
Bai, Y.2
Reece, J.M.3
Williams, J.4
Liu, D.5
Freeman, M.L.6
-
46
-
-
0033731182
-
Regulation of the antioxidant response element by protein kinase C-mediated phosphorylation of NF-E2-related factor 2
-
Huang H.C., Nguyen T., Pickett B. Regulation of the antioxidant response element by protein kinase C-mediated phosphorylation of NF-E2-related factor 2. Proc Natl Acad Sci USA 2000, 97(23):12475-12480.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.23
, pp. 12475-12480
-
-
Huang, H.C.1
Nguyen, T.2
Pickett, B.3
-
47
-
-
0041742490
-
A typical protein kinase C mediates activation of NF-E2-related factor 2 in response to oxidative stress
-
Numazawa S., Ishikawa M., Yoshida A., Tanaka S., Yoshida T. A typical protein kinase C mediates activation of NF-E2-related factor 2 in response to oxidative stress. Am J Physiol Cell Physiol 2003, 285(2):C334-C342.
-
(2003)
Am J Physiol Cell Physiol
, vol.285
, Issue.2
-
-
Numazawa, S.1
Ishikawa, M.2
Yoshida, A.3
Tanaka, S.4
Yoshida, T.5
-
48
-
-
0035034848
-
Activation of phosphatidylinositol 3-kinase and Akt by tert-butylhydroquinone is responsible for antioxidant response element-mediated rGSTA2 induction in H4IIE cells
-
Kang K.W., Cho M.K., Lee C.H., Kim S.G. Activation of phosphatidylinositol 3-kinase and Akt by tert-butylhydroquinone is responsible for antioxidant response element-mediated rGSTA2 induction in H4IIE cells. Mol Pharmacol 2001, 59(5):1147-1156.
-
(2001)
Mol Pharmacol
, vol.59
, Issue.5
, pp. 1147-1156
-
-
Kang, K.W.1
Cho, M.K.2
Lee, C.H.3
Kim, S.G.4
-
49
-
-
0038537298
-
PI3K is a key molecule in the Nrf2-mediated regulation of antioxidative proteins by hemin in human neuroblastoma cells
-
Nakaso K., Yano H., Fukuhara Y., Takeshima T., Wada-Isoe K., Nakashima K. PI3K is a key molecule in the Nrf2-mediated regulation of antioxidative proteins by hemin in human neuroblastoma cells. FEBS Lett 2003, 546(2-3):181-184.
-
(2003)
FEBS Lett
, vol.546
, Issue.2-3
, pp. 181-184
-
-
Nakaso, K.1
Yano, H.2
Fukuhara, Y.3
Takeshima, T.4
Wada-Isoe, K.5
Nakashima, K.6
-
50
-
-
0036840585
-
Phosphatidylinositol 3-kinase regulates nuclear translocation of NF-E2-related factor 2 through actin rearrangement in response to oxidative stress
-
Kang K.W., Lee S.J., Park J.W., Kim S.G. Phosphatidylinositol 3-kinase regulates nuclear translocation of NF-E2-related factor 2 through actin rearrangement in response to oxidative stress. Mol Pharmacol 2002, 62(5):1001-1010.
-
(2002)
Mol Pharmacol
, vol.62
, Issue.5
, pp. 1001-1010
-
-
Kang, K.W.1
Lee, S.J.2
Park, J.W.3
Kim, S.G.4
-
51
-
-
2242451441
-
Phosphorylation of transcriptional coactivator peroxisome proliferator-activated receptor (PPAR)-binding protein (PBP): stimulation of transcriptional regulation by mitogen-activated protein kinase
-
Misra P., Owuor E.D., Li W., Yu S., Qi C., Meyer K., et al. Phosphorylation of transcriptional coactivator peroxisome proliferator-activated receptor (PPAR)-binding protein (PBP): stimulation of transcriptional regulation by mitogen-activated protein kinase. J Biol Chem 2002, 277(50):48745-48754.
-
(2002)
J Biol Chem
, vol.277
, Issue.50
, pp. 48745-48754
-
-
Misra, P.1
Owuor, E.D.2
Li, W.3
Yu, S.4
Qi, C.5
Meyer, K.6
-
52
-
-
0034723357
-
P38 mitogen-activated protein kinase negatively regulates the induction of phase II drug-metabolizing enzymes that detoxify carcinogens
-
Yu R., Mandlekar S., Lei W., Fahl W.E., Tan T.H., Kong A.N. p38 mitogen-activated protein kinase negatively regulates the induction of phase II drug-metabolizing enzymes that detoxify carcinogens. J Biol Chem 2000, 275(4):2322-2327.
-
(2000)
J Biol Chem
, vol.275
, Issue.4
, pp. 2322-2327
-
-
Yu, R.1
Mandlekar, S.2
Lei, W.3
Fahl, W.E.4
Tan, T.H.5
Kong, A.N.6
-
53
-
-
0037569694
-
Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element
-
Balogun E., Hoque M., Gong P., Killeen E., Green C.J., Foresti R., et al. Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element. Biochem J 2003, 371(Pt 3):887-895.
-
(2003)
Biochem J
, vol.371
, Issue.PART 3
, pp. 887-895
-
-
Balogun, E.1
Hoque, M.2
Gong, P.3
Killeen, E.4
Green, C.J.5
Foresti, R.6
-
54
-
-
33744950387
-
Glycogen synthase kinase-3β inhibits the xenobiotic and antioxidant cell response by direct phosphorylation and nuclear exclusion of the transcription factor Nrf2
-
Salazar M., Rojo A.I., Velasco D., de Sagarra R.M., Cuadrado A. Glycogen synthase kinase-3β inhibits the xenobiotic and antioxidant cell response by direct phosphorylation and nuclear exclusion of the transcription factor Nrf2. J Biol Chem 2006, 281(21):14841-14851.
-
(2006)
J Biol Chem
, vol.281
, Issue.21
, pp. 14841-14851
-
-
Salazar, M.1
Rojo, A.I.2
Velasco, D.3
de Sagarra, R.M.4
Cuadrado, A.5
-
55
-
-
34447526197
-
GSK-3beta acts upstream of Fyn kinase in regulation of nuclear export and degradation of NF-E2 related factor 2
-
Jain A.K., Jaiswal A.K. GSK-3beta acts upstream of Fyn kinase in regulation of nuclear export and degradation of NF-E2 related factor 2. J Biol Chem 2007, 282(22):16502-16510.
-
(2007)
J Biol Chem
, vol.282
, Issue.22
, pp. 16502-16510
-
-
Jain, A.K.1
Jaiswal, A.K.2
-
56
-
-
33744953050
-
Phosphorylation of tyrosine 568 controls nuclear export of Nrf2
-
Jain A.K., Jaiswal A.K. Phosphorylation of tyrosine 568 controls nuclear export of Nrf2. J Biol Chem 2006, 281(17):12132-12142.
-
(2006)
J Biol Chem
, vol.281
, Issue.17
, pp. 12132-12142
-
-
Jain, A.K.1
Jaiswal, A.K.2
-
57
-
-
33748752586
-
Nrf2 possesses a redox-sensitive nuclear exporting signal in the Neh5 transactivation domain
-
Li W., Yu S.-W., Kong A.N.T. Nrf2 possesses a redox-sensitive nuclear exporting signal in the Neh5 transactivation domain. J Biol Chem 2006, 281(37):27251-27263.
-
(2006)
J Biol Chem
, vol.281
, Issue.37
, pp. 27251-27263
-
-
Li, W.1
Yu, S.-W.2
Kong, A.N.T.3
-
58
-
-
18944373186
-
Keap1 regulates the oxidation-sensitive shuttling of Nrf2 into and out of the nucleus via a Crm1-dependent nuclear export mechanism
-
Velichkova M., Hasson T. Keap1 regulates the oxidation-sensitive shuttling of Nrf2 into and out of the nucleus via a Crm1-dependent nuclear export mechanism. Mol Cell Biol 2005, 25(11):4501-4513.
-
(2005)
Mol Cell Biol
, vol.25
, Issue.11
, pp. 4501-4513
-
-
Velichkova, M.1
Hasson, T.2
-
59
-
-
34548772935
-
Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2
-
Sun Z., Zhang S., Chan J.Y., Zhang D.D. Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2. Mol Cell Biol 2007, 27(18):6334-6349.
-
(2007)
Mol Cell Biol
, vol.27
, Issue.18
, pp. 6334-6349
-
-
Sun, Z.1
Zhang, S.2
Chan, J.Y.3
Zhang, D.D.4
-
60
-
-
67649415378
-
Prothymosin-α mediates nuclear import of INrf2/Cul3-Rbx1 complex to degrade nuclear Nrf2
-
Niture S.K., Jaiswal A.K. Prothymosin-α mediates nuclear import of INrf2/Cul3-Rbx1 complex to degrade nuclear Nrf2. J Biol Chem 2009, 284(20):13856-13868.
-
(2009)
J Biol Chem
, vol.284
, Issue.20
, pp. 13856-13868
-
-
Niture, S.K.1
Jaiswal, A.K.2
-
61
-
-
20444480956
-
Bach1 competes with Nrf2 leading to negative regulation of the antioxidant response element (ARE)-mediated NAD(P)H:quinone oxidoreductase 1 gene expression and induction in response to antioxidants
-
Dhakshinamoorthy S., Jain A.K., Bloom D.A., Jaiswal A.K. Bach1 competes with Nrf2 leading to negative regulation of the antioxidant response element (ARE)-mediated NAD(P)H:quinone oxidoreductase 1 gene expression and induction in response to antioxidants. J Biol Chem 2005, 280(17):16891-16900.
-
(2005)
J Biol Chem
, vol.280
, Issue.17
, pp. 16891-16900
-
-
Dhakshinamoorthy, S.1
Jain, A.K.2
Bloom, D.A.3
Jaiswal, A.K.4
-
62
-
-
0033862118
-
Chemoprevention studies of the flavonoids quercetin and rutin in normal and azoxymethane-treated mouse colon
-
Yang K., Lamprecht S.A., Liu Y., Shinozaki H., Fan K., Leung D., et al. Chemoprevention studies of the flavonoids quercetin and rutin in normal and azoxymethane-treated mouse colon. Carcinogenesis 2000, 21(9):1655-1660.
-
(2000)
Carcinogenesis
, vol.21
, Issue.9
, pp. 1655-1660
-
-
Yang, K.1
Lamprecht, S.A.2
Liu, Y.3
Shinozaki, H.4
Fan, K.5
Leung, D.6
-
63
-
-
0036195968
-
Genistein chemoprevention: timing and mechanisms of action in murine mammary and prostate
-
Lamartiniere C.A., Cotroneo M.S., Fritz W.A., Wang J., Mentor-Marcel R., Elgavish A. Genistein chemoprevention: timing and mechanisms of action in murine mammary and prostate. J Nutr 2002, 132(3):552S-558S.
-
(2002)
J Nutr
, vol.132
, Issue.3
-
-
Lamartiniere, C.A.1
Cotroneo, M.S.2
Fritz, W.A.3
Wang, J.4
Mentor-Marcel, R.5
Elgavish, A.6
-
64
-
-
39249085843
-
Modulation of Nrf2-mediated antioxidant and detoxifying enzyme induction by the green tea polyphenol EGCG
-
Na H.K., Surh Y.J. Modulation of Nrf2-mediated antioxidant and detoxifying enzyme induction by the green tea polyphenol EGCG. Food Chem Toxicol 2008, 46(4):1271-1278.
-
(2008)
Food Chem Toxicol
, vol.46
, Issue.4
, pp. 1271-1278
-
-
Na, H.K.1
Surh, Y.J.2
-
65
-
-
43249101846
-
Polymeric black tea polyphenols induce phase II enzymes via Nrf2 in mouse liver and lungs
-
Patel R., Maru G. Polymeric black tea polyphenols induce phase II enzymes via Nrf2 in mouse liver and lungs. Free Radic Biol Med 2008, 44(11):1897-1911.
-
(2008)
Free Radic Biol Med
, vol.44
, Issue.11
, pp. 1897-1911
-
-
Patel, R.1
Maru, G.2
-
66
-
-
5144230473
-
Cancer-preventive isothiocyanates: measurement of human exposure and mechanism of action
-
Zhang Y. Cancer-preventive isothiocyanates: measurement of human exposure and mechanism of action. Mutat Res 2004, 555(1-2):173-190.
-
(2004)
Mutat Res
, vol.555
, Issue.1-2
, pp. 173-190
-
-
Zhang, Y.1
-
67
-
-
0037106099
-
Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotidemicroarray
-
Thimmulappa R.K., Mai K.H., Srisuma S., Kensler T.W., Yamamoto M., Biswal S. Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotidemicroarray. Cancer Res 2002, 62(18):5196-5203.
-
(2002)
Cancer Res
, vol.62
, Issue.18
, pp. 5196-5203
-
-
Thimmulappa, R.K.1
Mai, K.H.2
Srisuma, S.3
Kensler, T.W.4
Yamamoto, M.5
Biswal, S.6
-
68
-
-
0346888660
-
Sulforaphane and quercetin modulate PhIP-DNA adduct formation in human HepG2 cells and hepatocytes
-
Bacon J.R., Williamson G., Garner R.C., Lappin G., Langouet S., Bao Y. Sulforaphane and quercetin modulate PhIP-DNA adduct formation in human HepG2 cells and hepatocytes. Carcinogenesis 2003, 24(12):1903-1911.
-
(2003)
Carcinogenesis
, vol.24
, Issue.12
, pp. 1903-1911
-
-
Bacon, J.R.1
Williamson, G.2
Garner, R.C.3
Lappin, G.4
Langouet, S.5
Bao, Y.6
-
69
-
-
0037418625
-
Differential responses from seven mammalian cell lines to the treatments of detoxifying enzyme inducers
-
Jiang Z.Q., Chen C., Yang B., Hebbar V., Kong A.N. Differential responses from seven mammalian cell lines to the treatments of detoxifying enzyme inducers. Life Sci 2003, 72(20):2243-2253.
-
(2003)
Life Sci
, vol.72
, Issue.20
, pp. 2243-2253
-
-
Jiang, Z.Q.1
Chen, C.2
Yang, B.3
Hebbar, V.4
Kong, A.N.5
-
70
-
-
0036045433
-
Sulforaphane and its glutathione conjugate but not sulforaphane nitrile induce UDP-glucuronosyl transferase (UGT1A1) and glutathione transferase (GSTA1) in cultured cells
-
Basten G.P., Bao Y., Williamson G. Sulforaphane and its glutathione conjugate but not sulforaphane nitrile induce UDP-glucuronosyl transferase (UGT1A1) and glutathione transferase (GSTA1) in cultured cells. Carcinogenesis 2002, 23(8):1399-1404.
-
(2002)
Carcinogenesis
, vol.23
, Issue.8
, pp. 1399-1404
-
-
Basten, G.P.1
Bao, Y.2
Williamson, G.3
-
71
-
-
0034854057
-
Potent induction of phase 2 enzymes in human prostate cells by sulforaphane
-
Brooks J.D., Paton V.G., Vidanes G. Potent induction of phase 2 enzymes in human prostate cells by sulforaphane. Cancer Epidemiol Biomarkers Prev 2001, 10(9):949-954.
-
(2001)
Cancer Epidemiol Biomarkers Prev
, vol.10
, Issue.9
, pp. 949-954
-
-
Brooks, J.D.1
Paton, V.G.2
Vidanes, G.3
-
72
-
-
0026577605
-
A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure
-
Zhang Y., Talalay P., Cho C.G., Posner G.H. A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure. Proc Natl Acad Sci USA 1992, 89(6):2399-2403.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, Issue.6
, pp. 2399-2403
-
-
Zhang, Y.1
Talalay, P.2
Cho, C.G.3
Posner, G.H.4
-
73
-
-
33645468736
-
Modest induction of phase 2 enzyme activity in the F-344 rat prostate
-
Jones S.B., Brooks J.D. Modest induction of phase 2 enzyme activity in the F-344 rat prostate. BMC Cancer 2006, 6:62-70.
-
(2006)
BMC Cancer
, vol.6
, pp. 62-70
-
-
Jones, S.B.1
Brooks, J.D.2
-
74
-
-
34247473917
-
Induction of the phase 2 response in mouse and human skin by sulforaphane-containing broccoli sprout extracts
-
Dinkova-Kostova A.T., Fahey J.W., Wade K.L., Jenkins S.N., Shapiro T.A., Fuchs E.J., et al. Induction of the phase 2 response in mouse and human skin by sulforaphane-containing broccoli sprout extracts. Cancer Epidemiol Biomarkers Prev 2007, 16(4):847-851.
-
(2007)
Cancer Epidemiol Biomarkers Prev
, vol.16
, Issue.4
, pp. 847-851
-
-
Dinkova-Kostova, A.T.1
Fahey, J.W.2
Wade, K.L.3
Jenkins, S.N.4
Shapiro, T.A.5
Fuchs, E.J.6
-
75
-
-
59249103720
-
Oral sulforaphane increases Phase II antioxidant enzymes in the human upper airway
-
Riedl M.A., Saxon A., Diaz-Sanchez D. Oral sulforaphane increases Phase II antioxidant enzymes in the human upper airway. Clin Immunol 2009, 130(3):244-251.
-
(2009)
Clin Immunol
, vol.130
, Issue.3
, pp. 244-251
-
-
Riedl, M.A.1
Saxon, A.2
Diaz-Sanchez, D.3
-
76
-
-
55949121573
-
Tissue differences in the modulation of rat cytochromes P450 and phase II conjugation systems by dietary doses of phenethyl isothiocyanate
-
Konsue N., Ioannides C. Tissue differences in the modulation of rat cytochromes P450 and phase II conjugation systems by dietary doses of phenethyl isothiocyanate. Food Chem Toxicol 2008, 46(12):3677-3683.
-
(2008)
Food Chem Toxicol
, vol.46
, Issue.12
, pp. 3677-3683
-
-
Konsue, N.1
Ioannides, C.2
-
77
-
-
0033746135
-
7-Methylsulfinylheptyl and 8-methylsulfinyloctyl isothiocyanates from watercress are potent inducers of phase II enzymes
-
Rose P., Faulkner K., Williamson G., Mithen R. 7-Methylsulfinylheptyl and 8-methylsulfinyloctyl isothiocyanates from watercress are potent inducers of phase II enzymes. Carcinogenesis 2000, 21(11):1983-1988.
-
(2000)
Carcinogenesis
, vol.21
, Issue.11
, pp. 1983-1988
-
-
Rose, P.1
Faulkner, K.2
Williamson, G.3
Mithen, R.4
-
78
-
-
0027055359
-
Effects of phenethyl isothiocyanate, a carcinogenesis inhibitor, on xenobiotic-metabolizing enzymes and nitrosamine metabolism in rats
-
Guo Z., Smith T.J., Wang E., Sadrieh N., Ma Q., Thomas P.E., et al. Effects of phenethyl isothiocyanate, a carcinogenesis inhibitor, on xenobiotic-metabolizing enzymes and nitrosamine metabolism in rats. Carcinogenesis 1992, 13(12):2205-2210.
-
(1992)
Carcinogenesis
, vol.13
, Issue.12
, pp. 2205-2210
-
-
Guo, Z.1
Smith, T.J.2
Wang, E.3
Sadrieh, N.4
Ma, Q.5
Thomas, P.E.6
-
79
-
-
33749263503
-
Identification of Nrf2-regulated genes induced by chemopreventive isothiocyanate PEITC by oligonucleotide microarray
-
Hu R., Xu C., Shen G., Jain M.R., Khor T.O., Gopalkrishnan A., et al. Identification of Nrf2-regulated genes induced by chemopreventive isothiocyanate PEITC by oligonucleotide microarray. Life Sci 2006, 79(20):1944-1955.
-
(2006)
Life Sci
, vol.79
, Issue.20
, pp. 1944-1955
-
-
Hu, R.1
Xu, C.2
Shen, G.3
Jain, M.R.4
Khor, T.O.5
Gopalkrishnan, A.6
-
80
-
-
9744283511
-
Transcription factor Nrf2 is essential for induction of NAD(P)H:quinone oxidoreductase 1, glutathione S-transferases, and glutamate cysteine ligase by broccoli seeds and isothiocyanates
-
McWalter G.K., Higgins L.G., McLellan L.I., Henderson C.J., Song L., Thornalley P.J., et al. Transcription factor Nrf2 is essential for induction of NAD(P)H:quinone oxidoreductase 1, glutathione S-transferases, and glutamate cysteine ligase by broccoli seeds and isothiocyanates. J Nutr 2004, 134(12 Suppl):3499S-3506S.
-
(2004)
J Nutr
, vol.134
, Issue.12 SUPPL
-
-
McWalter, G.K.1
Higgins, L.G.2
McLellan, L.I.3
Henderson, C.J.4
Song, L.5
Thornalley, P.J.6
-
81
-
-
0033600914
-
Role of a mitogen-activated protein kinase pathway in the induction of phase II detoxifying enzymes by chemicals
-
Yu R., Lei W., Mandlekar S., Weber M.J., Der C.J., Wu J., et al. Role of a mitogen-activated protein kinase pathway in the induction of phase II detoxifying enzymes by chemicals. J Biol Chem 1999, 274(39):27545-27552.
-
(1999)
J Biol Chem
, vol.274
, Issue.39
, pp. 27545-27552
-
-
Yu, R.1
Lei, W.2
Mandlekar, S.3
Weber, M.J.4
Der, C.J.5
Wu, J.6
-
82
-
-
0141567455
-
Involvement of Nrf 2 and JNK1 in the activation of antioxidant responsive element (ARE) by chemopreventive agent phenethyl Isothiocyanate (PEITC)
-
Keum Y.S., Owuor E.D., Kim B.R., Hu R., Kong A-N.T. Involvement of Nrf 2 and JNK1 in the activation of antioxidant responsive element (ARE) by chemopreventive agent phenethyl Isothiocyanate (PEITC). Pharm Res 2003, 20(9):1351-1356.
-
(2003)
Pharm Res
, vol.20
, Issue.9
, pp. 1351-1356
-
-
Keum, Y.S.1
Owuor, E.D.2
Kim, B.R.3
Hu, R.4
Kong, A.-N.T.5
-
83
-
-
33748358379
-
Mechanism of action of isothiocyanates: the induction of ARE-regulated genes is associated with activation of ERK and JNK and the phosphorylation and nuclear translocation of Nrf2
-
Xu C., Yuan X., Pan Z., Shen G., Kim J.H., Yu S., et al. Mechanism of action of isothiocyanates: the induction of ARE-regulated genes is associated with activation of ERK and JNK and the phosphorylation and nuclear translocation of Nrf2. Mol Cancer Ther 2006, 5(8):1918-1926.
-
(2006)
Mol Cancer Ther
, vol.5
, Issue.8
, pp. 1918-1926
-
-
Xu, C.1
Yuan, X.2
Pan, Z.3
Shen, G.4
Kim, J.H.5
Yu, S.6
-
84
-
-
33747876093
-
The chemopreventive efficacy of inhaled oltipraz particulates in the B[a]P-induced A/J mouse lung adenoma model
-
Sharma S., Gao P., Steele V.E. The chemopreventive efficacy of inhaled oltipraz particulates in the B[a]P-induced A/J mouse lung adenoma model. Carcinogenesis 2006, 27(8):1721-1727.
-
(2006)
Carcinogenesis
, vol.27
, Issue.8
, pp. 1721-1727
-
-
Sharma, S.1
Gao, P.2
Steele, V.E.3
-
85
-
-
0023204238
-
Mechanism of protection against aflatoxin tumorigenicity in rats fed 5-(2-pyrazinyl)-4-methyl-1, 2-dithiol-3-thione (oltipraz) and related 1,2-dithiol-3-thiones and 1,2-dithiol-3-ones
-
Kensler T., Egner P., Dolan P., Groopman J., Roebuck B. Mechanism of protection against aflatoxin tumorigenicity in rats fed 5-(2-pyrazinyl)-4-methyl-1, 2-dithiol-3-thione (oltipraz) and related 1,2-dithiol-3-thiones and 1,2-dithiol-3-ones. Cancer Res 1987, 47(16):4271-4277.
-
(1987)
Cancer Res
, vol.47
, Issue.16
, pp. 4271-4277
-
-
Kensler, T.1
Egner, P.2
Dolan, P.3
Groopman, J.4
Roebuck, B.5
-
86
-
-
0037014797
-
A randomized phase IIb trial of anethole dithiolethione in smokers with bronchial dysplasia
-
Lam S., MacAulay C., Le Riche J.C., Dyachkova Y., Coldman A., Guillaud M., et al. A randomized phase IIb trial of anethole dithiolethione in smokers with bronchial dysplasia. J Natl Cancer Inst 2002, 94(13):1001-1009.
-
(2002)
J Natl Cancer Inst
, vol.94
, Issue.13
, pp. 1001-1009
-
-
Lam, S.1
MacAulay, C.2
Le Riche, J.C.3
Dyachkova, Y.4
Coldman, A.5
Guillaud, M.6
-
87
-
-
0037298498
-
Induction of cellular glutathione and glutathione S-transferase by 3H-1,2-dithiole-3-thione in rat aortic smooth muscle A10 cells: protection against acrolein-induced toxicity
-
Cao Z., Hardej D., Trombetta L.D., Trush M.A., Li Y. Induction of cellular glutathione and glutathione S-transferase by 3H-1,2-dithiole-3-thione in rat aortic smooth muscle A10 cells: protection against acrolein-induced toxicity. Atherosclerosis 2003, 166(2):291-301.
-
(2003)
Atherosclerosis
, vol.166
, Issue.2
, pp. 291-301
-
-
Cao, Z.1
Hardej, D.2
Trombetta, L.D.3
Trush, M.A.4
Li, Y.5
-
88
-
-
34250187433
-
Glutathione and glutathione-linked enzymes in normal human aortic smooth muscle cells: chemical inducibility and protection against reactive oxygen and nitrogen species-induced injury
-
Zhu H., Cao Z., Zhang L., Trush M.A., Li Y. Glutathione and glutathione-linked enzymes in normal human aortic smooth muscle cells: chemical inducibility and protection against reactive oxygen and nitrogen species-induced injury. Mol Cell Biochem 2007, 301(1-2):47-59.
-
(2007)
Mol Cell Biochem
, vol.301
, Issue.1-2
, pp. 47-59
-
-
Zhu, H.1
Cao, Z.2
Zhang, L.3
Trush, M.A.4
Li, Y.5
-
89
-
-
0036423167
-
Induction of cellular glutathione-linked enzymes and catalase by the unique chemoprotective agent, 3H-1,2-dithiole-3-thione in rat cardiomyocytes affords protection against oxidative cell injury
-
Peng X., Li Y. Induction of cellular glutathione-linked enzymes and catalase by the unique chemoprotective agent, 3H-1,2-dithiole-3-thione in rat cardiomyocytes affords protection against oxidative cell injury. Pharmacol Res 2002, 45(6):491-497.
-
(2002)
Pharmacol Res
, vol.45
, Issue.6
, pp. 491-497
-
-
Peng, X.1
Li, Y.2
-
90
-
-
0035451390
-
Role of phase 2 enzyme induction in chemoprotection by dithiolethiones
-
Kwak M.K., Egner P.A., Dolan P.M., Ramos-Gomez M., Groopman J.D., Itoh K., et al. Role of phase 2 enzyme induction in chemoprotection by dithiolethiones. Mutat Res 2001, 480-481:305-315.
-
(2001)
Mutat Res
, pp. 305-315
-
-
Kwak, M.K.1
Egner, P.A.2
Dolan, P.M.3
Ramos-Gomez, M.4
Groopman, J.D.5
Itoh, K.6
-
91
-
-
0027105175
-
Mechanisms of chemoprotection by oltipraz
-
Kensler T., Styczynski P., Groopman J., Helzlsouer K., Curphey T., Maxuitenko Y., et al. Mechanisms of chemoprotection by oltipraz. J Cell Biochem 1992, 50(S16I):167-172.
-
(1992)
J Cell Biochem
, vol.50
, Issue.S 16
, pp. 167-172
-
-
Kensler, T.1
Styczynski, P.2
Groopman, J.3
Helzlsouer, K.4
Curphey, T.5
Maxuitenko, Y.6
-
92
-
-
0022763396
-
Inhibitory effects of 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione (oltipraz) on carcinogenesis induced by benzo[a]pyrene, diethylnitrosamine and uracil mustard
-
Wattenberg L.W., Bueding E. Inhibitory effects of 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione (oltipraz) on carcinogenesis induced by benzo[a]pyrene, diethylnitrosamine and uracil mustard. Carcinogenesis 1986, 7(8):1379-1381.
-
(1986)
Carcinogenesis
, vol.7
, Issue.8
, pp. 1379-1381
-
-
Wattenberg, L.W.1
Bueding, E.2
-
93
-
-
0036240610
-
Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences in the nrf2 promoter
-
Kwak M.K., Itoh K., Yamamoto M., Kensler T.W. Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences in the nrf2 promoter. Mol Cell Biol 2002, 22(9):2883-2892.
-
(2002)
Mol Cell Biol
, vol.22
, Issue.9
, pp. 2883-2892
-
-
Kwak, M.K.1
Itoh, K.2
Yamamoto, M.3
Kensler, T.W.4
-
94
-
-
0037424262
-
Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway
-
Kwak M.K., Wakabayashi N., Itoh K., Motohashi H., Yamamoto M., Kensler T.W. Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. J Biol Chem 2003, 278(10):8135-8145.
-
(2003)
J Biol Chem
, vol.278
, Issue.10
, pp. 8135-8145
-
-
Kwak, M.K.1
Wakabayashi, N.2
Itoh, K.3
Motohashi, H.4
Yamamoto, M.5
Kensler, T.W.6
-
95
-
-
35548952645
-
Induction of Nrf2-regulated genes by 3H-1, 2-dithiole-3-thione through the ERK signaling pathway in murine keratinocytes
-
Manandhar S., Cho J.M., Kim J.A., Kensler T.W., Kwak M.K. Induction of Nrf2-regulated genes by 3H-1, 2-dithiole-3-thione through the ERK signaling pathway in murine keratinocytes. Eur J Pharmacol 2007, 577(1-3):17-27.
-
(2007)
Eur J Pharmacol
, vol.577
, Issue.1-3
, pp. 17-27
-
-
Manandhar, S.1
Cho, J.M.2
Kim, J.A.3
Kensler, T.W.4
Kwak, M.K.5
-
96
-
-
0037245333
-
Essential role of phosphatidylinositol 3-kinase-dependent CCAAT/enhancer binding protein beta activation in the induction of glutathione S-transferase by oltipraz
-
Kang K.W., Cho I.J., Lee C.H., Kimm S.G. Essential role of phosphatidylinositol 3-kinase-dependent CCAAT/enhancer binding protein beta activation in the induction of glutathione S-transferase by oltipraz. J Natl Cancer Inst 2003, 95(1):53-66.
-
(2003)
J Natl Cancer Inst
, vol.95
, Issue.1
, pp. 53-66
-
-
Kang, K.W.1
Cho, I.J.2
Lee, C.H.3
Kimm, S.G.4
-
97
-
-
33745541339
-
Antithrombotic and anticancer effects of garlic-derived sulfur compounds: a review
-
Ariga T., Seki T. Antithrombotic and anticancer effects of garlic-derived sulfur compounds: a review. Biofactors 2006, 26(2):93-103.
-
(2006)
Biofactors
, vol.26
, Issue.2
, pp. 93-103
-
-
Ariga, T.1
Seki, T.2
-
98
-
-
5344220933
-
Induction of detoxifying enzymes by garlic organosulfur compounds through transcription factor NRF2: effect of chemical structure and stress signals
-
Chen C., Pung D., Leong V., Hebbar V., Shen G., Nair S., et al. Induction of detoxifying enzymes by garlic organosulfur compounds through transcription factor NRF2: effect of chemical structure and stress signals. Free Radic Biol Med 2004, 37(10):1578-1590.
-
(2004)
Free Radic Biol Med
, vol.37
, Issue.10
, pp. 1578-1590
-
-
Chen, C.1
Pung, D.2
Leong, V.3
Hebbar, V.4
Shen, G.5
Nair, S.6
-
99
-
-
34249094270
-
Induction of drug-metabolizing enzymes by garlic and allyl sulfide compounds via activation of constitutive androstane receptor and nuclear factor E2-related factor 2
-
Fisher C.D., Augustine L.M., Maher J.M., Nelson D.M., Slitt A.L., Klaassen C.D., et al. Induction of drug-metabolizing enzymes by garlic and allyl sulfide compounds via activation of constitutive androstane receptor and nuclear factor E2-related factor 2. Drug Metab Dispos 2007, 35(6):995-1000.
-
(2007)
Drug Metab Dispos
, vol.35
, Issue.6
, pp. 995-1000
-
-
Fisher, C.D.1
Augustine, L.M.2
Maher, J.M.3
Nelson, D.M.4
Slitt, A.L.5
Klaassen, C.D.6
-
100
-
-
0035001920
-
Effects of organosulfur compounds from garlic oil on the antioxidation system in rat liver and red blood cells
-
Wu C.C., Sheen L.Y., Chen H.W., Tsai S.J., Lii C.K. Effects of organosulfur compounds from garlic oil on the antioxidation system in rat liver and red blood cells. Food Chem Toxicol 2001, 39(6):563-569.
-
(2001)
Food Chem Toxicol
, vol.39
, Issue.6
, pp. 563-569
-
-
Wu, C.C.1
Sheen, L.Y.2
Chen, H.W.3
Tsai, S.J.4
Lii, C.K.5
-
101
-
-
70349627876
-
Induced expression of drugmetabolizing enzymes by preventive agents: role of the antioxidant response element
-
Lubet R.A., Yao R., Grubbs C.J., You M., Wang Y. Induced expression of drugmetabolizing enzymes by preventive agents: role of the antioxidant response element. Chem Biol Interact 2009, 182(1):22-28.
-
(2009)
Chem Biol Interact
, vol.182
, Issue.1
, pp. 22-28
-
-
Lubet, R.A.1
Yao, R.2
Grubbs, C.J.3
You, M.4
Wang, Y.5
-
102
-
-
7944220437
-
Diallyl sulfide induces heme oxygenase-1 through MAPK pathway
-
Gong P., Hu B., Cederbaum A.I. Diallyl sulfide induces heme oxygenase-1 through MAPK pathway. Arch Biochem Biophys 2004, 432(2):252-260.
-
(2004)
Arch Biochem Biophys
, vol.432
, Issue.2
, pp. 252-260
-
-
Gong, P.1
Hu, B.2
Cederbaum, A.I.3
-
103
-
-
51349127271
-
Multitargeted cancer prevention by quercetin
-
Murakami A., Ashida H., Terao J. Multitargeted cancer prevention by quercetin. Cancer Lett 2008, 269(2):315-325.
-
(2008)
Cancer Lett
, vol.269
, Issue.2
, pp. 315-325
-
-
Murakami, A.1
Ashida, H.2
Terao, J.3
-
104
-
-
0025885064
-
Quercetin and rutin as inhibitors of azoxymethanol-induced colonic neoplasia
-
Deschner E.E., Ruperto J., Wong G., Newmark H.L. Quercetin and rutin as inhibitors of azoxymethanol-induced colonic neoplasia. Carcinogenesis 1991, 12(7):1193-1196.
-
(1991)
Carcinogenesis
, vol.12
, Issue.7
, pp. 1193-1196
-
-
Deschner, E.E.1
Ruperto, J.2
Wong, G.3
Newmark, H.L.4
-
105
-
-
0023681264
-
Inhibition of 7,12-dimethylbenz(a)anthracene- and N-nitrosomethylurea-induced rat mammary cancer by dietary flavonol quercetin
-
Verma A.K., Johnson J.A., Gould M.N., Tanner M.A. Inhibition of 7,12-dimethylbenz(a)anthracene- and N-nitrosomethylurea-induced rat mammary cancer by dietary flavonol quercetin. Cancer Res 1988, 48(20):5754-5758.
-
(1988)
Cancer Res
, vol.48
, Issue.20
, pp. 5754-5758
-
-
Verma, A.K.1
Johnson, J.A.2
Gould, M.N.3
Tanner, M.A.4
-
106
-
-
67651042484
-
Essential role of Nrf2 in keratinocyte protection from UVA by quercetin
-
Kimura S., Warabi E., Yanagawa T., Ma D., Itoh K., Ishii Y., et al. Essential role of Nrf2 in keratinocyte protection from UVA by quercetin. Biochem Biophys Res Commun 2009, 387(1):109-114.
-
(2009)
Biochem Biophys Res Commun
, vol.387
, Issue.1
, pp. 109-114
-
-
Kimura, S.1
Warabi, E.2
Yanagawa, T.3
Ma, D.4
Itoh, K.5
Ishii, Y.6
-
107
-
-
34347392509
-
Quercetin protects human hepatocytes from ethanol-derived oxidative stress by inducing heme oxygenase-1 via the MAPK/Nrf2 pathways
-
Yao P., Nussler A., Liu L., Hao L., Song F., Schirmeier A., et al. Quercetin protects human hepatocytes from ethanol-derived oxidative stress by inducing heme oxygenase-1 via the MAPK/Nrf2 pathways. J Hepatol 2007, 47(2):253-261.
-
(2007)
J Hepatol
, vol.47
, Issue.2
, pp. 253-261
-
-
Yao, P.1
Nussler, A.2
Liu, L.3
Hao, L.4
Song, F.5
Schirmeier, A.6
-
108
-
-
34247282872
-
Action of Nrf2 and Keap1 in ARE-mediated NQO1 expression by quercetin
-
Tanigawa S., Fujii M., Hou D.X. Action of Nrf2 and Keap1 in ARE-mediated NQO1 expression by quercetin. Free Radic Biol Med 2007, 42(11):1690-1703.
-
(2007)
Free Radic Biol Med
, vol.42
, Issue.11
, pp. 1690-1703
-
-
Tanigawa, S.1
Fujii, M.2
Hou, D.X.3
-
109
-
-
33644647678
-
Intracellular signaling network as a prime chemopreventive target of (-)-epigallocatechin gallate
-
Na H.K., Surh Y.J. Intracellular signaling network as a prime chemopreventive target of (-)-epigallocatechin gallate. Mol Nutr Food Res 2006, 50(2):152-159.
-
(2006)
Mol Nutr Food Res
, vol.50
, Issue.2
, pp. 152-159
-
-
Na, H.K.1
Surh, Y.J.2
-
110
-
-
33744976109
-
Molecular targets for the cancer preventive activity of tea polyphenols
-
Yang C.S., Lambert J.D., Hou Z., Ju J., Lu G., Hao X. Molecular targets for the cancer preventive activity of tea polyphenols. Mol Carcinog 2006, 45(6):431-435.
-
(2006)
Mol Carcinog
, vol.45
, Issue.6
, pp. 431-435
-
-
Yang, C.S.1
Lambert, J.D.2
Hou, Z.3
Ju, J.4
Lu, G.5
Hao, X.6
-
111
-
-
33646179260
-
Upregulation of heme oxygenase-1 by Epigallocatechin-3-gallate via the phosphatidylinositol 3-kinase/Akt and ERK pathways
-
Wu C.C., Hsu M.C., Hsieh C.W., Lin J.B., Lai P.H., Wung B.S. Upregulation of heme oxygenase-1 by Epigallocatechin-3-gallate via the phosphatidylinositol 3-kinase/Akt and ERK pathways. Life Sci 2006, 78(25):889-897.
-
(2006)
Life Sci
, vol.78
, Issue.25
, pp. 889-897
-
-
Wu, C.C.1
Hsu, M.C.2
Hsieh, C.W.3
Lin, J.B.4
Lai, P.H.5
Wung, B.S.6
-
112
-
-
48049089409
-
(-)-Epigallocatechin gallate induces Nrf2-mediated antioxidant enzyme expression via activation of PI3K and ERK in human mammary epithelial cells
-
Na H.K., Kim E.H., Jung J.H., Lee H.H., Hyun J.W., Surh Y.J. (-)-Epigallocatechin gallate induces Nrf2-mediated antioxidant enzyme expression via activation of PI3K and ERK in human mammary epithelial cells. Arch Biochem Biophys 2008, 476(2):171-177.
-
(2008)
Arch Biochem Biophys
, vol.476
, Issue.2
, pp. 171-177
-
-
Na, H.K.1
Kim, E.H.2
Jung, J.H.3
Lee, H.H.4
Hyun, J.W.5
Surh, Y.J.6
-
113
-
-
33644838918
-
Involvement of Nrf2, p38, B-Raf, and nuclear factor-kappaB, but not phosphatidylinositol 3-kinase, in induction of hemeoxygenase-1 by dietary polyphenols
-
Andreadi C.K., Howells L.M., Atherfold P.A., Manson M.M. Involvement of Nrf2, p38, B-Raf, and nuclear factor-kappaB, but not phosphatidylinositol 3-kinase, in induction of hemeoxygenase-1 by dietary polyphenols. Mol Pharmacol 2006, 69(3):1033-1040.
-
(2006)
Mol Pharmacol
, vol.69
, Issue.3
, pp. 1033-1040
-
-
Andreadi, C.K.1
Howells, L.M.2
Atherfold, P.A.3
Manson, M.M.4
-
114
-
-
27144450869
-
Comparison of (-)-epigallocatechin-3-gallate elicited liver and small intestine gene expression profiles between C57BL/6J mice and C57BL/6J/Nrf2 (-/-) mice
-
Shen G., Xu C., Hu R., Jain M.R., Nair S., Lin W., et al. Comparison of (-)-epigallocatechin-3-gallate elicited liver and small intestine gene expression profiles between C57BL/6J mice and C57BL/6J/Nrf2 (-/-) mice. Pharm Res 2005, 22(11):1805-1820.
-
(2005)
Pharm Res
, vol.22
, Issue.11
, pp. 1805-1820
-
-
Shen, G.1
Xu, C.2
Hu, R.3
Jain, M.R.4
Nair, S.5
Lin, W.6
-
115
-
-
67349202556
-
Epigallocatechin-3-gallate augments antioxidant activities and inhibits inflammation during bleomycin-induced experimental pulmonary fibrosis through Nrf2-Keap1 signaling
-
Sriram N., Kalayarasan S., Sudhandiran G. Epigallocatechin-3-gallate augments antioxidant activities and inhibits inflammation during bleomycin-induced experimental pulmonary fibrosis through Nrf2-Keap1 signaling. Pulm Pharmacol Ther 2009, 22(3):221-236.
-
(2009)
Pulm Pharmacol Ther
, vol.22
, Issue.3
, pp. 221-236
-
-
Sriram, N.1
Kalayarasan, S.2
Sudhandiran, G.3
-
116
-
-
32944475325
-
Synthesis and structure identification of thiol conjugates of (-)-epigallocatechin gallate and their urinary levels in mice
-
Sang S., Lambert J.D., Hong J., Tian S., Lee M.J., Stark R.E., et al. Synthesis and structure identification of thiol conjugates of (-)-epigallocatechin gallate and their urinary levels in mice. Chem Res Toxicol 2005, 18(11):1762-1769.
-
(2005)
Chem Res Toxicol
, vol.18
, Issue.11
, pp. 1762-1769
-
-
Sang, S.1
Lambert, J.D.2
Hong, J.3
Tian, S.4
Lee, M.J.5
Stark, R.E.6
-
117
-
-
0034573074
-
Activation of antioxidant-response element (ARE), mitogen-activated protein kinases (MAPKs) and caspases by major green tea polyphenol components during cell survival and death
-
Chen C., Yu R., Owuor E.D., Kong A.N. Activation of antioxidant-response element (ARE), mitogen-activated protein kinases (MAPKs) and caspases by major green tea polyphenol components during cell survival and death. Arch Pharm Res 2000, 23(6):605-612.
-
(2000)
Arch Pharm Res
, vol.23
, Issue.6
, pp. 605-612
-
-
Chen, C.1
Yu, R.2
Owuor, E.D.3
Kong, A.N.4
-
118
-
-
0026615189
-
Inhibitory effects of curcumin on tumor initiation by benzo[a]-pyrene and 7,12-dimethylbenz[a]anthracene
-
Huang M.T., Wang Z.Y., Georgiadis C.A., Laskin J.D., Conney A.H. Inhibitory effects of curcumin on tumor initiation by benzo[a]-pyrene and 7,12-dimethylbenz[a]anthracene. Carcinogenesis 1992, 13(11):2183-2186.
-
(1992)
Carcinogenesis
, vol.13
, Issue.11
, pp. 2183-2186
-
-
Huang, M.T.1
Wang, Z.Y.2
Georgiadis, C.A.3
Laskin, J.D.4
Conney, A.H.5
-
119
-
-
33644853063
-
Modulation of nuclear factor E2-related factor 2-mediated gene expression in mice liver and small intestine by cancer chemopreventive agent curcumin
-
Shen G., Xu C., Hu R., Jain M.R., Gopalkrishnan A., Nair S., et al. Modulation of nuclear factor E2-related factor 2-mediated gene expression in mice liver and small intestine by cancer chemopreventive agent curcumin. Mol Cancer Ther 2006, 5(1):39-51.
-
(2006)
Mol Cancer Ther
, vol.5
, Issue.1
, pp. 39-51
-
-
Shen, G.1
Xu, C.2
Hu, R.3
Jain, M.R.4
Gopalkrishnan, A.5
Nair, S.6
-
120
-
-
34248186574
-
Curcumin activates human glutathione S-transferase P1 expression through antioxidant response element
-
Nishinaka T., Ichijo Y., Ito M., Kimura M., Katsuyama M., Iwata K., et al. Curcumin activates human glutathione S-transferase P1 expression through antioxidant response element. Toxicol Lett 2007, 170(3):238-247.
-
(2007)
Toxicol Lett
, vol.170
, Issue.3
, pp. 238-247
-
-
Nishinaka, T.1
Ichijo, Y.2
Ito, M.3
Kimura, M.4
Katsuyama, M.5
Iwata, K.6
-
121
-
-
59249104565
-
Curcumin protects retinal cells from light-and oxidant stress-induced cell death
-
Mandal M.N., Patlolla J.M., Zheng L., Agbaga M.P., Tran J.T., Wicker L., et al. Curcumin protects retinal cells from light-and oxidant stress-induced cell death. Free Radic Biol Med 2009, 46(5):672-679.
-
(2009)
Free Radic Biol Med
, vol.46
, Issue.5
, pp. 672-679
-
-
Mandal, M.N.1
Patlolla, J.M.2
Zheng, L.3
Agbaga, M.P.4
Tran, J.T.5
Wicker, L.6
-
122
-
-
32344432720
-
Role of protein kinase C δ in curcumin-induced antioxidant response element-mediated gene expression in human monocytes
-
Rushworth S.A., Ogborne R.M., Charalambos C.A., O'Connell M.A. Role of protein kinase C δ in curcumin-induced antioxidant response element-mediated gene expression in human monocytes. Biochem Biophys Res Commun 2006, 341(4):1007-1016.
-
(2006)
Biochem Biophys Res Commun
, vol.341
, Issue.4
, pp. 1007-1016
-
-
Rushworth, S.A.1
Ogborne, R.M.2
Charalambos, C.A.3
O'Connell, M.A.4
-
123
-
-
34548429119
-
Regulation of heme oxygenase-1 expression by demethoxy curcuminoids through Nrf2 by a PI3-kinase/Akt-mediated pathway in mouse beta cells
-
Pugazhenthi S., Akhov L., Selvaraj G., Wang M., Alam J. Regulation of heme oxygenase-1 expression by demethoxy curcuminoids through Nrf2 by a PI3-kinase/Akt-mediated pathway in mouse beta cells. Am J Physiol Endocrinol Metab 2007, 293(3):E645-E655.
-
(2007)
Am J Physiol Endocrinol Metab
, vol.293
, Issue.3
-
-
Pugazhenthi, S.1
Akhov, L.2
Selvaraj, G.3
Wang, M.4
Alam, J.5
-
124
-
-
34447328075
-
Up-regulation of aldose reductase expression mediated by phosphatidylinositol 3-kinase/Akt and Nrf2 is involved in the protective effect of curcumin against oxidative damage
-
Kang E.S., Woo I.S., Kim H.J., Eun S.Y., Paek K.S., Kim H.J., et al. Up-regulation of aldose reductase expression mediated by phosphatidylinositol 3-kinase/Akt and Nrf2 is involved in the protective effect of curcumin against oxidative damage. Free Radic Biol Med 2007, 43(4):535-545.
-
(2007)
Free Radic Biol Med
, vol.43
, Issue.4
, pp. 535-545
-
-
Kang, E.S.1
Woo, I.S.2
Kim, H.J.3
Eun, S.Y.4
Paek, K.S.5
Kim, H.J.6
-
125
-
-
61449208761
-
Oleanolic acid activates Nrf2 and protects from acetaminophen hepatotoxicity via Nrf2-dependent and Nrf2-independent processes
-
Reisman S.A., Aleksunes L.M., Klaassen C.D. Oleanolic acid activates Nrf2 and protects from acetaminophen hepatotoxicity via Nrf2-dependent and Nrf2-independent processes. Biochem Pharmacol 2009, 77(7):1273-1282.
-
(2009)
Biochem Pharmacol
, vol.77
, Issue.7
, pp. 1273-1282
-
-
Reisman, S.A.1
Aleksunes, L.M.2
Klaassen, C.D.3
-
126
-
-
40049107014
-
2-induced Nrf2/ARE activation
-
2-induced Nrf2/ARE activation. Biochem Biophys Res Commun 2008, 368(4):948-954.
-
(2008)
Biochem Biophys Res Commun
, vol.368
, Issue.4
, pp. 948-954
-
-
Umemura, K.1
Itoh, T.2
Hamada, N.3
Fujita, Y.4
Akao, Y.5
Nozawa, Y.6
-
127
-
-
13944262936
-
Carotenoids activate the antioxidant response element transcription system
-
Ben-Dor A., Steiner M., Gheber L., Danilenko M., Dubi N., Linnewiel K., et al. Carotenoids activate the antioxidant response element transcription system. Mol Cancer Ther 2005, 4(1):177-186.
-
(2005)
Mol Cancer Ther
, vol.4
, Issue.1
, pp. 177-186
-
-
Ben-Dor, A.1
Steiner, M.2
Gheber, L.3
Danilenko, M.4
Dubi, N.5
Linnewiel, K.6
-
128
-
-
60349128328
-
Comparison of citrus coumarins on carcinogen-detoxifying enzymes in Nrf2 knockout mice
-
Prince M., Li Y., Childers A., Itoh K., Yamamoto M., Kleiner H.E. Comparison of citrus coumarins on carcinogen-detoxifying enzymes in Nrf2 knockout mice. Toxicol Lett 2009, 185(3):180-186.
-
(2009)
Toxicol Lett
, vol.185
, Issue.3
, pp. 180-186
-
-
Prince, M.1
Li, Y.2
Childers, A.3
Itoh, K.4
Yamamoto, M.5
Kleiner, H.E.6
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