Sulforaphane and quercetin modulate PhIP-DNA adduct formation in human HepG2 cells and hepatocytes

Carcinogenesis

Volumn 24, Issue 12, 2003, Pages 1903-1911

  Bacon, James R ^a   Williamson, Gary ^a,d   Garner, R Colin ^b   Lappin, Graham ^b   Langouët, Sophie ^c   Bao, Yongping ^a  

^a INSTITUTE OF FOOD RESEARCH   (United Kingdom)

^b Xceleron Ltd   (United Kingdom)

^c UNIVERSITÉ DE RENNES 1   (France)

^d NESTLÉ RESEARCH CENTER   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 1 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; CARBON 14; CARCINOGEN; CYTOCHROME P450 1A2; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; DNA DIRECTED DNA POLYMERASE BETA; FLAVONOID; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE; ISOTHIOCYANIC ACID; MESSENGER RNA; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; QUERCETIN; SULFORAPHANE;

ARTICLE; CELL PROTECTION; CELL STRAIN HEPG2; CONCENTRATION RESPONSE; CONTROLLED STUDY; DETOXIFICATION; DIETARY INTAKE; DNA ADDUCT; DNA REPAIR; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INDUCTION; ENZYME INHIBITION; EXPOSURE; HUMAN; HUMAN CELL; ISOTOPE LABELING; LINEAR SYSTEM; LIVER CELL; MASS SPECTROMETER; NUCLEOTIDE SEQUENCE; PHYTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STATISTICAL SIGNIFICANCE; VARIANCE;

ANTICARCINOGENIC AGENTS; BIOLOGICAL MARKERS; CARCINOGENS; CELL LINE; CELL LINE, TUMOR; CYTOCHROME P-450 CYP1A2; DNA ADDUCTS; DNA POLYMERASE BETA; DNA REPAIR; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTATHIONE TRANSFERASE; HEPATOCYTES; HUMANS; IMIDAZOLES; ISOTHIOCYANATES; MASS SPECTROMETRY; QUERCETIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; RNA, MESSENGER; THIOCYANATES; TIME FACTORS;

EID: 0346888660     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/bgg157     Document Type: Article

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