Regulation of heme oxygenase-1 expression by demethoxy curcuminoids through Nrf2 by a PI3-kinase/Akt-mediated pathway in mouse β-cells

American Journal of Physiology - Endocrinology and Metabolism

Volumn 293, Issue 3, 2007, Pages

  Pugazhenthi, Subbiah ^a,b   Akhov, Leonid ^c   Selvaraj, Gopalan ^c   Wang, Maorong ^a,b   Alam, Jawed ^d  

^a UNIVERSITY OF COLORADO   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^d OCHSNER MEDICAL CENTER   (United States)

Author keywords

Diabetes; Oxidative stress; Pancreatic cells; Phase 2 enzymes

Indexed keywords

BISDEMETHOXY CURCUMIN; CURCUMIN; DEMETHOXY CURCUMIN; GLUTAMYL CYSTEINE LIGASE; GLUTATHIONE; HEME OXYGENASE 1; LIGASE; LUCIFERASE; NADPH:QUINONE OXIDOREDUCTASE; OXIDOREDUCTASE; PHOSPHOTIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE; PROTEIN KINASE B; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; DIABETES MELLITUS; DRUG SYNTHESIS; ENHANCER REGION; ENZYME ACTIVITY; IMMUNOCYTOCHEMISTRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL LINE; CURCUMIN; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION, ENZYMOLOGIC; INSULIN-SECRETING CELLS; MICE; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 34548429119     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00111.2007     Document Type: Article

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