Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling

EMBO Journal

Volumn 25, Issue 15, 2006, Pages 3605-3617

  Lo, Shih Ching ^a,b   Li, Xuchu ^a,b   Henzl, Michael T ^a   Beamer, Lesa J ^a   Hannink, Mark ^a,b  

^a University of Missouri   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

Author keywords

BTB Kelch proteins; Chemoprevention; Cullin dependent ubiquitin ligases; Oxidative stress; Substrate adaptor proteins

Indexed keywords

ADAPTOR PROTEIN; ASPARTIC ACID; PROTEIN KEAP1; PROTEIN KELCH; THREONINE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STRAIN COS1; CONTROLLED STUDY; HUMAN; HUMAN CELL; HYDROGEN BOND; MUTAGENESIS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; CONSERVED SEQUENCE; COS CELLS; DIMERIZATION; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NF-E2-RELATED FACTOR 2; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION;

EID: 33747606306     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601243     Document Type: Article

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