메뉴 건너뛰기




Volumn 15, Issue 3, 2010, Pages 1105-1118

To fuse or not to fuse: How do checkpoint and DNA repair proteins maintain telomeres?

Author keywords

DNA damage checkpoint; DNA repair; Pot1; Review; Shelterin; Telomerase; Telomere

Indexed keywords

EUKARYOTA;

EID: 77956640538     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/3664     Document Type: Article
Times cited : (3)

References (135)
  • 1
    • 0035093737 scopus 로고    scopus 로고
    • DNA double-strand breaks: Signaling, repair and the cancer connection
    • DOI 10.1038/85798
    • Khanna, K. K. & S. P. Jackson: DNA double-strand breaks: signaling, repair and the cancer connection. Nat Genet, 27(3), 247-54 (2001). (Pubitemid 32201842)
    • (2001) Nature Genetics , vol.27 , Issue.3 , pp. 247-254
    • Khanna, K.K.1    Jackson, S.P.2
  • 2
    • 46249125488 scopus 로고    scopus 로고
    • How shelterin protects mammalian telomeres
    • Palm, W. & T. de Lange: How shelterin protects mammalian telomeres. Annu Rev Genet, 42, 301-34 (2008).
    • (2008) Annu Rev Genet , vol.42 , pp. 301-334
    • Palm, W.1    De Lange, T.2
  • 3
    • 68249143290 scopus 로고    scopus 로고
    • Taming the tiger by the tail: Modulation of DNA damage responses by telomeres
    • Lydall, D.: Taming the tiger by the tail: modulation of DNA damage responses by telomeres. EMBO J, 28(15), 2174-2187 (2009).
    • (2009) EMBO J , vol.28 , Issue.15 , pp. 2174-2187
    • Lydall, D.1
  • 4
    • 38349073475 scopus 로고    scopus 로고
    • DNA damage response at functional and dysfunctional telomeres
    • Longhese, M. P.: DNA damage response at functional and dysfunctional telomeres. Genes Dev, 22(2), 125-40 (2008).
    • (2008) Genes Dev , vol.22 , Issue.2 , pp. 125-140
    • Longhese, M.P.1
  • 5
    • 77649180958 scopus 로고    scopus 로고
    • Telomeres: Protecting chromosomes against genome instability
    • O'Sullivan, R. J. & J. Karlseder: Telomeres: protecting chromosomes against genome instability. Nat Rev Mol Cell Biol, 11(3), 171-81 (2010).
    • (2010) Nat Rev Mol Cell Biol , vol.11 , Issue.3 , pp. 171-181
    • O'Sullivan, R.J.1    Karlseder, J.2
  • 6
    • 47549086947 scopus 로고    scopus 로고
    • How Telomerase Reaches Its End: Mechanism of Telomerase Regulation by the Telomeric Complex
    • DOI 10.1016/j.molcel.2008.06.013, PII S1097276508004310
    • Bianchi, A. & D. Shore: How telomerase reaches its end: mechanism of telomerase regulation by the telomeric complex. Mol Cell, 31(2), 153-65 (2008). (Pubitemid 352005819)
    • (2008) Molecular Cell , vol.31 , Issue.2 , pp. 153-165
    • Bianchi, A.1    Shore, D.2
  • 7
    • 59649130294 scopus 로고    scopus 로고
    • Telomerase recruitment to telomeres
    • Stern, J. L. & T. M. Bryan: Telomerase recruitment to telomeres. Cytogenet Genome Res, 122(3-4), 243-54 (2008).
    • (2008) Cytogenet Genome Res , vol.122 , Issue.3-4 , pp. 243-254
    • Stern, J.L.1    Bryan, T.M.2
  • 8
    • 33751419716 scopus 로고    scopus 로고
    • Surviving the breakup: The DNA damage checkpoint
    • DOI 10.1146/annurev.genet.40.051206.105231
    • Harrison, J. C. & J. E. Haber: Surviving the breakup: the DNA damage checkpoint. Annu Rev Genet, 40, 209-35 (2006). (Pubitemid 44956785)
    • (2006) Annual Review of Genetics , vol.40 , pp. 209-235
    • Harrison, J.C.1    Haber, J.E.2
  • 9
    • 0036531901 scopus 로고    scopus 로고
    • A unified view of the DNA-damage checkpoint
    • DOI 10.1016/S0955-0674(02)00312-5
    • Melo, J. & D. Toczyski: A unified view of the DNA-damage checkpoint. Curr Opin Cell Biol, 14(2), 237-45 (2002). (Pubitemid 34219514)
    • (2002) Current Opinion in Cell Biology , vol.14 , Issue.2 , pp. 237-245
    • Melo, J.1    Toczyski, D.2
  • 10
    • 9244251125 scopus 로고    scopus 로고
    • Cell-cycle checkpoints and cancer
    • DOI 10.1038/nature03097
    • Kastan, M. B. & J. Bartek: Cell-cycle checkpoints and cancer. Nature, 432(7015), 316-23 (2004). (Pubitemid 39551659)
    • (2004) Nature , vol.432 , Issue.7015 , pp. 316-323
    • Kastan, M.B.1    Bartek, J.2
  • 11
    • 17644409069 scopus 로고    scopus 로고
    • ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
    • DOI 10.1126/science.1108297
    • Lee, J. H. & T. T. Paull: ATM activation by DNA doublestrand breaks through the Mre11-Rad50-Nbs1 complex. Science, 308(5721), 551-4 (2005). (Pubitemid 40570585)
    • (2005) Science , vol.308 , Issue.5721 , pp. 551-554
    • Lee, J.-H.1    Paull, T.T.2
  • 12
    • 15844394846 scopus 로고    scopus 로고
    • Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage
    • DOI 10.1038/nature03442
    • Falck, J., J. Coates & S. P. Jackson: Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage. Nature, 434(7033), 605-11 (2005). (Pubitemid 40488547)
    • (2005) Nature , vol.434 , Issue.7033 , pp. 605-611
    • Falck, J.1    Coates, J.2    Jackson, S.P.3
  • 13
    • 20744436198 scopus 로고    scopus 로고
    • ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1
    • DOI 10.1128/MCB.25.13.5363-5379.2005
    • You, Z., C. Chahwan, J. Bailis, T. Hunter & P. Russell: ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1. Mol Cell Biol, 25(13), 5363-79 (2005). (Pubitemid 40853574)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.13 , pp. 5363-5379
    • You, Z.1    Chahwan, C.2    Bailis, J.3    Hunter, T.4    Russell, P.5
  • 14
    • 33745058037 scopus 로고    scopus 로고
    • Two-step activation of ATM by DNA and the Mre11-Rad50-Nbs1 complex
    • DOI 10.1038/nsmb1090, PII N1090
    • Dupre, A., L. Boyer-Chatenet & J. Gautier: Two-step activation of ATM by DNA and the Mre11-Rad50-Nbs1 complex. Nat Struct Mol Biol, 13(5), 451-7 (2006). (Pubitemid 43881586)
    • (2006) Nature Structural and Molecular Biology , vol.13 , Issue.5 , pp. 451-457
    • Dupre, A.1    Boyer-Chatenet, L.2    Gautier, J.3
  • 16
    • 33745823159 scopus 로고    scopus 로고
    • The ATM-mediated DNA-damage response: taking shape
    • DOI 10.1016/j.tibs.2006.05.004, PII S0968000406001381
    • Shiloh, Y.: The ATM-mediated DNA-damage response: taking shape. Trends Biochem Sci, 31(7), 402-10 (2006). (Pubitemid 44038916)
    • (2006) Trends in Biochemical Sciences , vol.31 , Issue.7 , pp. 402-410
    • Shiloh, Y.1
  • 17
    • 30344463835 scopus 로고    scopus 로고
    • ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks
    • DOI 10.1038/ncb1337, PII N1337
    • Jazayeri, A., J. Falck, C. Lukas, J. Bartek, G. C. Smith, J. Lukas & S. P. Jackson: ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks. Nat Cell Biol, 8(1), 37-45 (2006). (Pubitemid 43064795)
    • (2006) Nature Cell Biology , vol.8 , Issue.1 , pp. 37-45
    • Jazayeri, A.1    Falck, J.2    Lukas, C.3    Bartek, J.4    Smith, G.C.M.5    Lukas, J.6    Jackson, S.P.7
  • 18
    • 33646777679 scopus 로고    scopus 로고
    • Rapid activation of ATR by ionizing radiation requires ATM and Mre11
    • DOI 10.1074/jbc.M513265200
    • Myers, J. S. & D. Cortez: Rapid activation of ATR by ionizing radiation requires ATM and Mre11. J Biol Chem, 281(14), 9346-50 (2006). (Pubitemid 43864651)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.14 , pp. 9346-9350
    • Myers, J.S.1    Cortez, D.2
  • 20
    • 33646795891 scopus 로고    scopus 로고
    • Recruitment of ATR to sites of ionising radiation-induced DNA damage requires ATM and components of the MRN protein complex
    • DOI 10.1038/sj.onc.1209426, PII 1209426
    • Adams, K. E., A. L. Medhurst, D. A. Dart & N. D. Lakin: Recruitment of ATR to sites of ionising radiation-induced DNA damage requires ATM and components of the MRN protein complex. Oncogene, 25(28), 3894-904 (2006). (Pubitemid 43990744)
    • (2006) Oncogene , vol.25 , Issue.28 , pp. 3894-3904
    • Adams, K.E.1    Medhurst, A.L.2    Dart, D.A.3    Lakin, N.D.4
  • 21
    • 0037567268 scopus 로고    scopus 로고
    • Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
    • DOI 10.1126/science.1083430
    • Zou, L. & S. J. Elledge: Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science, 300(5625), 1542-8 (2003). (Pubitemid 36682880)
    • (2003) Science , vol.300 , Issue.5625 , pp. 1542-1548
    • Zou, L.1    Elledge, S.J.2
  • 22
    • 61649093808 scopus 로고    scopus 로고
    • Single-stranded DNA orchestrates an ATM-to-ATR switch at DNA breaks
    • Shiotani, B. & L. Zou: Single-stranded DNA orchestrates an ATM-to-ATR switch at DNA breaks. Mol Cell, 33(5), 547-58 (2009).
    • (2009) Mol Cell , vol.33 , Issue.5 , pp. 547-558
    • Shiotani, B.1    Zou, L.2
  • 23
    • 33845715977 scopus 로고    scopus 로고
    • ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling
    • DOI 10.1038/sj.emboj.7601446, PII 7601446
    • Stiff, T., S. A. Walker, K. Cerosaletti, A. A. Goodarzi, E. Petermann, P. Concannon, M. O'Driscoll & P. A. Jeggo: ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling. EMBO J, 25(24), 5775-82 (2006). (Pubitemid 44967761)
    • (2006) EMBO Journal , vol.25 , Issue.24 , pp. 5775-5782
    • Stiff, T.1    Walker, S.A.2    Cerosaletti, K.3    Goodarzi, A.A.4    Petermann, E.5    Concannon, P.6    O'Driscoll, M.7    Jeggo, P.A.8
  • 24
    • 67649111979 scopus 로고    scopus 로고
    • Crystal structure of the rad9-rad1-hus1 DNA damage checkpoint complex-implications for clamp loading and regulation
    • Dore, A. S., M. L. Kilkenny, N. J. Rzechorzek & L. H. Pearl: Crystal structure of the rad9-rad1-hus1 DNA damage checkpoint complex-implications for clamp loading and regulation. Mol Cell, 34(6), 735-45 (2009).
    • (2009) Mol Cell , vol.34 , Issue.6 , pp. 735-745
    • Dore, A.S.1    Kilkenny, M.L.2    Rzechorzek, N.J.3    Pearl, L.H.4
  • 25
    • 44849093460 scopus 로고    scopus 로고
    • TopBP1 activates ATR through ATRIP and a PIKK regulatory domain
    • DOI 10.1101/gad.1666208
    • Mordes, D. A., G. G. Glick, R. Zhao & D. Cortez: TopBP1 activates ATR through ATRIP and a PIKK regulatory domain. Genes Dev, 22(11), 1478-89 (2008). (Pubitemid 351793082)
    • (2008) Genes and Development , vol.22 , Issue.11 , pp. 1478-1489
    • Mordes, D.A.1    Glick, G.G.2    Zhao, R.3    Cortez, D.4
  • 26
    • 33845607102 scopus 로고    scopus 로고
    • The Checkpoint Clamp Activates Mec1 Kinase during Initiation of the DNA Damage Checkpoint
    • DOI 10.1016/j.molcel.2006.11.027, PII S1097276506008239
    • Majka, J., A. Niedziela-Majka & P. M. Burgers: The checkpoint clamp activates Mec1 kinase during initiation of the DNA damage checkpoint. Mol Cell, 24(6), 891-901 (2006). (Pubitemid 44960097)
    • (2006) Molecular Cell , vol.24 , Issue.6 , pp. 891-901
    • Majka, J.1    Niedziela-Majka, A.2    Burgers, PeterM.J.3
  • 27
    • 64249120749 scopus 로고    scopus 로고
    • Replicon dynamics, dormant origin firing, and terminal fork integrity after double-strand break formation
    • Doksani, Y., R. Bermejo, S. Fiorani, J. E. Haber & M. Foiani: Replicon dynamics, dormant origin firing, and terminal fork integrity after double-strand break formation. Cell, 137(2), 247-58 (2009).
    • (2009) Cell , vol.137 , Issue.2 , pp. 247-258
    • Doksani, Y.1    Bermejo, R.2    Fiorani, S.3    Haber, J.E.4    Foiani, M.5
  • 28
    • 0034899458 scopus 로고    scopus 로고
    • In vitro reconstitution of the end replication problem
    • DOI 10.1128/MCB.21.17.5753-5766.2001
    • Ohki, R., T. Tsurimoto & F. Ishikawa: In vitro reconstitution of the end replication problem. Mol Cell Biol, 21(17), 5753-66 (2001). (Pubitemid 32737793)
    • (2001) Molecular and Cellular Biology , vol.21 , Issue.17 , pp. 5753-5766
    • Ohki, R.1    Tsurimoto, T.2    Ishikawa, F.3
  • 29
    • 0032793298 scopus 로고    scopus 로고
    • Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae
    • Ritchie, K. B., J. C. Mallory & T. D. Petes: Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae. Mol Cell Biol, 19(9), 6065-75 (1999). (Pubitemid 29399312)
    • (1999) Molecular and Cellular Biology , vol.19 , Issue.9 , pp. 6065-6075
    • Ritchie, K.B.1    Mallory, J.C.2    Petes, T.D.3
  • 30
    • 0031686574 scopus 로고    scopus 로고
    • Circular chromosome formation in a fission yeast mutant defective in two ATM homologues
    • DOI 10.1038/2517
    • Naito, T., A. Matsuura & F. Ishikawa: Circular chromosome formation in a fission yeast mutant defective in two ATM homologues. Nat Genet, 20(2), 203-6 (1998). (Pubitemid 28455457)
    • (1998) Nature Genetics , vol.20 , Issue.2 , pp. 203-206
    • Naito, T.1    Matsuura, A.2    Ishikawa, F.3
  • 33
    • 33947308706 scopus 로고    scopus 로고
    • Early Replication of Short Telomeres in Budding Yeast
    • DOI 10.1016/j.cell.2007.01.041, PII S0092867407002425
    • Bianchi, A. & D. Shore: Early replication of short telomeres in budding yeast. Cell, 128(6), 1051-62 (2007). (Pubitemid 46437258)
    • (2007) Cell , vol.128 , Issue.6 , pp. 1051-1062
    • Bianchi, A.1    Shore, D.2
  • 34
    • 34648843213 scopus 로고    scopus 로고
    • How telomeres are replicated
    • DOI 10.1038/nrm2259, PII NRM2259
    • Gilson, E. & V. Geli: How telomeres are replicated. Nat Rev Mol Cell Biol, 8(10), 825-38 (2007). (Pubitemid 47462137)
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.10 , pp. 825-838
    • Gilson, E.1    Geli, V.2
  • 36
    • 33749059184 scopus 로고    scopus 로고
    • DNA Degradation at Unprotected Telomeres in Yeast Is Regulated by the CDK1 (Cdc28/Clb) Cell-Cycle Kinase
    • DOI 10.1016/j.molcel.2006.07.035, PII S1097276506005399
    • Vodenicharov, M. D. & R. J. Wellinger: DNA degradation at unprotected telomeres in yeast is regulated by the CDK1 (Cdc28/Clb) cell-cycle kinase. Mol Cell, 24(1), 127-37 (2006). (Pubitemid 44466679)
    • (2006) Molecular Cell , vol.24 , Issue.1 , pp. 127-137
    • Vodenicharov, M.D.1    Wellinger, R.J.2
  • 38
    • 34548317418 scopus 로고    scopus 로고
    • Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1
    • DOI 10.1038/nature06065, PII NATURE06065
    • Denchi, E. L. & T. de Lange: Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1. Nature, 448(7157), 1068-71 (2007). (Pubitemid 47345583)
    • (2007) Nature , vol.448 , Issue.7157 , pp. 1068-1071
    • Denchi, E.L.1    De Lange, T.2
  • 39
    • 37849030208 scopus 로고    scopus 로고
    • Pot1 and cell cycle progression cooperate in telomere length regulation
    • Churikov, D. & C. M. Price: Pot1 and cell cycle progression cooperate in telomere length regulation. Nat Struct Mol Biol, 15(1), 79-84 (2008).
    • (2008) Nat Struct Mol Biol , vol.15 , Issue.1 , pp. 79-84
    • Churikov, D.1    Price, C.M.2
  • 40
    • 19344374569 scopus 로고    scopus 로고
    • The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response
    • Karlseder, J., K. Hoke, O. K. Mirzoeva, C. Bakkenist, M. B. Kastan, J. H. Petrini & T. de Lange: The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response. PLoS Biol, 2(8), E240 (2004).
    • (2004) PLoS Biol , vol.2 , Issue.8
    • Karlseder, J.1    Hoke, K.2    Mirzoeva, O.K.3    Bakkenist, C.4    Kastan, M.B.5    Petrini, J.H.6    De Lange, T.7
  • 41
    • 67349246601 scopus 로고    scopus 로고
    • The shelterin protein TRF2 inhibits Chk2 activity at telomeres in the absence of DNA damage
    • Buscemi, G., L. Zannini, E. Fontanella, D. Lecis, S. Lisanti & D. Delia: The shelterin protein TRF2 inhibits Chk2 activity at telomeres in the absence of DNA damage. Curr Biol, 19(10), 874-9 (2009).
    • (2009) Curr Biol , vol.19 , Issue.10 , pp. 874-879
    • Buscemi, G.1    Zannini, L.2    Fontanella, E.3    Lecis, D.4    Lisanti, S.5    Delia, D.6
  • 42
    • 0342561644 scopus 로고    scopus 로고
    • Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres
    • DOI 10.1038/77139
    • Zhu, X. D., B. Kuster, M. Mann, J. H. Petrini & T. de Lange: Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres. Nat Genet, 25(3), 347-52 (2000). (Pubitemid 30437327)
    • (2000) Nature Genetics , vol.25 , Issue.3 , pp. 347-352
    • Zhu, X.-D.1    Kuster, B.2    Mann, M.3    Petrini, J.H.J.4    De Lange, T.5
  • 43
    • 33745652501 scopus 로고    scopus 로고
    • Apollo, an Artemis-related nuclease, interacts with TRF2 and protects human telomeres in S phase
    • van Overbeek, M. & T. de Lange: Apollo, an Artemis-related nuclease, interacts with TRF2 and protects human telomeres in S phase. Curr Biol, 16(13), 1295-302 (2006).
    • (2006) Curr Biol , vol.16 , Issue.13 , pp. 1295-1302
    • Van Overbeek, M.1    De Lange, T.2
  • 44
    • 33745651993 scopus 로고    scopus 로고
    • The Apollo 5' Exonuclease Functions Together with TRF2 to Protect Telomeres from DNA Repair
    • DOI 10.1016/j.cub.2006.05.021, PII S096098220601565X
    • Lenain, C., S. Bauwens, S. Amiard, M. Brunori, M. J. Giraud-Panis & E. Gilson: The Apollo 5' exonuclease functions together with TRF2 to protect telomeres from DNA repair. Curr Biol, 16(13), 1303-10 (2006). (Pubitemid 43996886)
    • (2006) Current Biology , vol.16 , Issue.13 , pp. 1303-1310
    • Lenain, C.1    Bauwens, S.2    Amiard, S.3    Brunori, M.4    Giraud-Panis, M.-J.5    Gilson, E.6
  • 46
    • 39749134753 scopus 로고    scopus 로고
    • A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins
    • DOI 10.1126/science.1151804
    • Chen, Y., Y. Yang, M. van Overbeek, J. R. Donigian, P. Baciu, T. de Lange & M. Lei: A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins. Science, 319(5866), 1092-6 (2008). (Pubitemid 351300791)
    • (2008) Science , vol.319 , Issue.5866 , pp. 1092-1096
    • Chen, Y.1    Yang, Y.2    Van Overbeek, M.3    Donigian, J.R.4    Baciu, P.5    De Lange, T.6    Lei, M.7
  • 47
    • 33745685066 scopus 로고    scopus 로고
    • Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres
    • Hockemeyer, D., J. P. Daniels, H. Takai & T. de Lange: Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres. Cell, 126(1), 63-77 (2006).
    • (2006) Cell , vol.126 , Issue.1 , pp. 63-77
    • Hockemeyer, D.1    Daniels, J.P.2    Takai, H.3    De Lange, T.4
  • 49
    • 34247600494 scopus 로고    scopus 로고
    • A RAP1/TRF2 Complex Inhibits Nonhomologous End-Joining at Human Telomeric DNA Ends
    • DOI 10.1016/j.molcel.2007.03.023, PII S1097276507002146
    • Bae, N. S. & P. Baumann: A RAP1/TRF2 complex inhibits nonhomologous end-joining at human telomeric DNA ends. Mol Cell, 26(3), 323-34 (2007). (Pubitemid 46687097)
    • (2007) Molecular Cell , vol.26 , Issue.3 , pp. 323-334
    • Bae, N.S.1    Baumann, P.2
  • 52
    • 45549090631 scopus 로고    scopus 로고
    • Fission yeast pot1-Tpp1 protects telomeres and regulates telomere length
    • DOI 10.1126/science.1154819
    • Miyoshi, T., J. Kanoh, M. Saito & F. Ishikawa: Fission yeast Pot1-Tpp1 protects telomeres and regulates telomere length. Science, 320(5881), 1341-4 (2008). (Pubitemid 351929470)
    • (2008) Science , vol.320 , Issue.5881 , pp. 1341-1344
    • Miyoshi, T.1    Kanoh, J.2    Saito, M.3    Ishikawa, F.4
  • 53
    • 3543064379 scopus 로고    scopus 로고
    • Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpoint
    • DOI 10.1101/gad.1216004
    • Silverman, J., H. Takai, S. B. Buonomo, F. Eisenhaber & T. de Lange: Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpoint. Genes Dev, 18(17), 2108-19 (2004). (Pubitemid 39166628)
    • (2004) Genes and Development , vol.18 , Issue.17 , pp. 2108-2119
    • Silverman, J.1    Takai, H.2    Buonomo, S.B.C.3    Eisenhaber, F.4    De Lange, T.5
  • 54
    • 10344235232 scopus 로고    scopus 로고
    • Human Rif1 protein binds aberrant telomeres and aligns along anaphase midzone microtubules
    • DOI 10.1083/jcb.200408181
    • Xu, L. & E. H. Blackburn: Human Rif1 protein binds aberrant telomeres and aligns along anaphase midzone microtubules. J Cell Biol, 167(5), 819-30 (2004). (Pubitemid 39628105)
    • (2004) Journal of Cell Biology , vol.167 , Issue.5 , pp. 819-830
    • Xu, L.1    Blackburn, E.H.2
  • 55
    • 0035899938 scopus 로고    scopus 로고
    • SpRap1 and spRif1, recruited to telomeres by Taz1, are essential for telomere function in fission yeast
    • DOI 10.1016/S0960-9822(01)00503-6
    • Kanoh, J. & F. Ishikawa: spRap1 and spRif1, recruited to telomeres by Taz1, are essential for telomere function in fission yeast. Curr Biol, 11(20), 1624-30 (2001). (Pubitemid 32978530)
    • (2001) Current Biology , vol.11 , Issue.20 , pp. 1624-1630
    • Kanoh, J.1    Ishikawa, F.2
  • 56
    • 0037292398 scopus 로고    scopus 로고
    • The telomere protein Taz1 is required to prevent and repair genomic DNA breaks
    • DOI 10.1016/S1097-2765(03)00041-8
    • Miller, K. M. & J. P. Cooper: The telomere protein Taz1 is required to prevent and repair genomic DNA breaks. Mol Cell, 11(2), 303-13 (2003). (Pubitemid 36293826)
    • (2003) Molecular Cell , vol.11 , Issue.2 , pp. 303-313
    • Miller, K.M.1    Cooper, J.P.2
  • 57
    • 0031038170 scopus 로고    scopus 로고
    • Regulation of telomere length and function by a Myb-domain protein in fission yeast
    • DOI 10.1038/385744a0
    • Cooper, J. P., E. R. Nimmo, R. C. Allshire & T. R. Cech: Regulation of telomere length and function by a Myb-domain protein in fission yeast. Nature, 385(6618), 744-7 (1997). (Pubitemid 27098098)
    • (1997) Nature , vol.385 , Issue.6618 , pp. 744-747
    • Cooper, J.P.1    Nimmo, E.R.2    Allshire, R.C.3    Cech, T.R.4
  • 58
    • 0035106262 scopus 로고    scopus 로고
    • The fission yeast Taz1 protein protects chromosomes from Ku-dependent end-to-end fusions
    • DOI 10.1016/S1097-2765(01)00154-X
    • Ferreira, M. G. & J. P. Cooper: The fission yeast Taz1 protein protects chromosomes from Ku-dependent end-toend fusions. Mol Cell, 7(1), 55-63 (2001). (Pubitemid 32162899)
    • (2001) Molecular Cell , vol.7 , Issue.1 , pp. 55-63
    • Ferreira, M.G.1    Cooper, J.P.2
  • 59
    • 4444339506 scopus 로고    scopus 로고
    • Two modes of DNA double-strand break repair are reciprocally regulated through the fission yeast cell cycle
    • DOI 10.1101/gad.315804
    • Ferreira, M. G. & J. P. Cooper: Two modes of DNA double-strand break repair are reciprocally regulated through the fission yeast cell cycle. Genes Dev, 18(18), 2249-54 (2004). (Pubitemid 39209573)
    • (2004) Genes and Development , vol.18 , Issue.18 , pp. 2249-2254
    • Ferreira, M.G.1    Cooper, J.P.2
  • 60
    • 27144495876 scopus 로고    scopus 로고
    • Taz1, Rap1 and Rif1 act both interdependently and independently to maintain telomeres
    • DOI 10.1038/sj.emboj.7600779, PII 7600779
    • Miller, K. M., M. G. Ferreira & J. P. Cooper: Taz1, Rap1 and Rif1 act both interdependently and independently to maintain telomeres. EMBO J, 24(17), 3128-35 (2005). (Pubitemid 41486348)
    • (2005) EMBO Journal , vol.24 , Issue.17 , pp. 3128-3135
    • Miller, K.M.1    Ferreira, M.G.2    Cooper, J.P.3
  • 61
    • 40749085686 scopus 로고    scopus 로고
    • Recombination-based telomere maintenance is dependent on Tel1-MRN and Rap1 and inhibited by telomerase, Taz1, and Ku in fission yeast
    • Subramanian, L., B. A. Moser & T. M. Nakamura: Recombination-based telomere maintenance is dependent on Tel1-MRN and Rap1 and inhibited by telomerase, Taz1, and Ku in fission yeast. Mol Cell Biol, 28(5), 1443-55 (2008).
    • (2008) Mol Cell Biol , vol.28 , Issue.5 , pp. 1443-1455
    • Subramanian, L.1    Moser, B.A.2    Nakamura, T.M.3
  • 62
    • 33645747064 scopus 로고    scopus 로고
    • Semiconservative DNA replication through telomeres requires Taz1
    • Miller, K. M., O. Rog & J. P. Cooper: Semiconservative DNA replication through telomeres requires Taz1. Nature, 440(7085), 824-8 (2006).
    • (2006) Nature , vol.440 , Issue.7085 , pp. 824-828
    • Miller, K.M.1    Rog, O.2    Cooper, J.P.3
  • 64
    • 58049204228 scopus 로고    scopus 로고
    • Fission yeast Ccq1 is telomerase recruiter and local checkpoint controller
    • Tomita, K. & J. P. Cooper: Fission yeast Ccq1 is telomerase recruiter and local checkpoint controller. Genes Dev, 22(24), 3461-74 (2008).
    • (2008) Genes Dev , vol.22 , Issue.24 , pp. 3461-3474
    • Tomita, K.1    Cooper, J.P.2
  • 65
    • 27144489538 scopus 로고    scopus 로고
    • Rap1 prevents telomere fusions by nonhomologous end joining
    • DOI 10.1038/sj.emboj.7600778, PII 7600778
    • Pardo, B. & S. Marcand: Rap1 prevents telomere fusions by nonhomologous end joining. EMBO J, 24(17), 3117-27 (2005). (Pubitemid 41486347)
    • (2005) EMBO Journal , vol.24 , Issue.17 , pp. 3117-3127
    • Pardo, B.1    Marcand, S.2
  • 67
    • 0035282781 scopus 로고    scopus 로고
    • Ten1 functions in telomere end protection and length regulation in association with Stn1 and Cdc13
    • DOI 10.1093/emboj/20.5.1173
    • Grandin, N., C. Damon & M. Charbonneau: Ten1 functions in telomere end protection and length regulation in association with Stn1 and Cdc13. EMBO J, 20(5), 1173-83 (2001). (Pubitemid 32186807)
    • (2001) EMBO Journal , vol.20 , Issue.5 , pp. 1173-1183
    • Grandin, N.1    Damon, C.2    Charbonneau, M.3
  • 68
    • 0028822203 scopus 로고
    • Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint
    • Garvik, B., M. Carson & L. Hartwell: Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint. Mol Cell Biol, 15(11), 6128-38 (1995).
    • (1995) Mol Cell Biol , vol.15 , Issue.11 , pp. 6128-6138
    • Garvik, B.1    Carson, M.2    Hartwell, L.3
  • 69
    • 0030447657 scopus 로고    scopus 로고
    • The Saccharomyces CDC13 protein is a single-strand TG1-3 telomeric DNA-binding protein in vitro that affects telomere behavior in vivo
    • Lin, J. J. & V. A. Zakian: The Saccharomyces CDC13 protein is a single-strand TG1-3 telomeric DNA-binding protein in vitro that affects telomere behavior in vivo. Proc Natl Acad Sci U S A, 93(24), 13760-5 (1996).
    • (1996) Proc Natl Acad Sci U S A , vol.93 , Issue.24 , pp. 13760-13765
    • Lin, J.J.1    Zakian, V.A.2
  • 70
    • 0029845892 scopus 로고    scopus 로고
    • Cdc13p: A single-strand telomeric DNA-binding protein with a dual role in yeast telomere maintenance
    • DOI 10.1126/science.274.5285.249
    • Nugent, C. I., T. R. Hughes, N. F. Lue & V. Lundblad: Cdc13p: a single-strand telomeric DNA-binding protein with a dual role in yeast telomere maintenance. Science, 274(5285), 249-52 (1996). (Pubitemid 26353202)
    • (1996) Science , vol.274 , Issue.5285 , pp. 249-252
    • Nugent, C.I.1    Hughes, T.R.2    Lue, N.F.3    Lundblad, V.4
  • 72
    • 70350031814 scopus 로고    scopus 로고
    • RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway
    • Miyake, Y., M. Nakamura, A. Nabetani, S. Shimamura, M. Tamura, S. Yonehara, M. Saito & F. Ishikawa: RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway. Mol Cell, 36(2), 193-206 (2009).
    • (2009) Mol Cell , vol.36 , Issue.2 , pp. 193-206
    • Miyake, Y.1    Nakamura, M.2    Nabetani, A.3    Shimamura, S.4    Tamura, M.5    Yonehara, S.6    Saito, M.7    Ishikawa, F.8
  • 75
    • 65549148649 scopus 로고    scopus 로고
    • A DNA polymerase-α•primase cofactor with homology to replication protein A-32 regulates DNA replication in mammalian cells
    • Casteel, D. E., S. Zhuang, Y. Zeng, F. W. Perrino, G. R. Boss, M. Goulian & R. B. Pilz: A DNA polymerase-α•primase cofactor with homology to replication protein A-32 regulates DNA replication in mammalian cells. J Biol Chem, 284(9), 5807-18 (2009).
    • (2009) J Biol Chem , vol.284 , Issue.9 , pp. 5807-5818
    • Casteel, D.E.1    Zhuang, S.2    Zeng, Y.3    Perrino, F.W.4    Boss, G.R.5    Goulian, M.6    Pilz, R.B.7
  • 76
    • 65449158366 scopus 로고    scopus 로고
    • Differential arrival of leading and lagging strand DNA polymerases at fission yeast telomeres
    • Moser, B. A., L. Subramanian, Y. T. Chang, C. Noguchi, E. Noguchi & T. M. Nakamura: Differential arrival of leading and lagging strand DNA polymerases at fission yeast telomeres. EMBO J, 28(7), 810-20 (2009).
    • (2009) EMBO J , vol.28 , Issue.7 , pp. 810-820
    • Moser, B.A.1    Subramanian, L.2    Chang, Y.T.3    Noguchi, C.4    Noguchi, E.5    Nakamura, T.M.6
  • 77
    • 70350001509 scopus 로고    scopus 로고
    • OB fold-containing protein 1 (OBFC1), a human homolog of yeast Stn1, associates with TPP1 and is implicated in telomere length regulation
    • Wan, M., J. Qin, Z. Songyang & D. Liu: OB fold-containing protein 1 (OBFC1), a human homolog of yeast Stn1, associates with TPP1 and is implicated in telomere length regulation. J Biol Chem, 284(39), 26725-31 (2009).
    • (2009) J Biol Chem , vol.284 , Issue.39 , pp. 26725-26731
    • Wan, M.1    Qin, J.2    Songyang, Z.3    Liu, D.4
  • 79
  • 80
    • 51049092483 scopus 로고    scopus 로고
    • Distinct roles for yeast Stn1 in telomere capping and telomerase inhibition
    • Puglisi, A., A. Bianchi, L. Lemmens, P. Damay & D. Shore: Distinct roles for yeast Stn1 in telomere capping and telomerase inhibition. EMBO J, 27(17), 2328-39 (2008).
    • (2008) EMBO J , vol.27 , Issue.17 , pp. 2328-2339
    • Puglisi, A.1    Bianchi, A.2    Lemmens, L.3    Damay, P.4    Shore, D.5
  • 81
    • 0034661246 scopus 로고    scopus 로고
    • The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase α and the telomerase-associated Est1 protein
    • Qi, H. & V. A. Zakian: The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase α and the telomerase-associated Est1 protein. Genes Dev, 14(14), 1777-88 (2000). (Pubitemid 30602996)
    • (2000) Genes and Development , vol.14 , Issue.14 , pp. 1777-1788
    • Qi, H.1    Zakian, V.A.2
  • 82
    • 33745751673 scopus 로고    scopus 로고
    • Chromosome end protection plasticity revealed by Stn1p and Ten1p bypass of Cdc13p
    • Petreaca, R. C., H. C. Chiu, H. A. Eckelhoefer, C. Chuang, L. Xu & C. I. Nugent: Chromosome end protection plasticity revealed by Stn1p and Ten1p bypass of Cdc13p. Nat Cell Biol, 8(7), 748-55 (2006).
    • (2006) Nat Cell Biol , vol.8 , Issue.7 , pp. 748-755
    • Petreaca, R.C.1    Chiu, H.C.2    Eckelhoefer, H.A.3    Chuang, C.4    Xu, L.5    Nugent, C.I.6
  • 83
    • 2442564703 scopus 로고    scopus 로고
    • Pol12, the B subunit of DNA polymerase α, functions in both telomere capping and length regulation
    • DOI 10.1101/gad.300004
    • Grossi, S., A. Puglisi, P. V. Dmitriev, M. Lopes & D. Shore: Pol12, the B subunit of DNA polymerase alpha, functions in both telomere capping and length regulation. Genes Dev, 18(9), 992-1006 (2004). (Pubitemid 38620240)
    • (2004) Genes and Development , vol.18 , Issue.9 , pp. 992-1006
    • Grossi, S.1    Puglisi, A.2    Dmitriev, P.V.3    Lopes, M.4    Shore, D.5
  • 84
    • 0028353634 scopus 로고
    • Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair
    • Weinert, T. A., G. L. Kiser & L. H. Hartwell: Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair. Genes Dev, 8(6), 652-65 (1994). (Pubitemid 24116760)
    • (1994) Genes and Development , vol.8 , Issue.6 , pp. 652-665
    • Weinert, T.A.1    Kiser, G.L.2    Hartwell, L.H.3
  • 85
    • 33745740664 scopus 로고    scopus 로고
    • Linear chromosome maintenance in the absence of essential telomere-capping proteins
    • Zubko, M. K. & D. Lydall: Linear chromosome maintenance in the absence of essential telomere-capping proteins. Nat Cell Biol, 8(7), 734-40 (2006).
    • (2006) Nat Cell Biol , vol.8 , Issue.7 , pp. 734-740
    • Zubko, M.K.1    Lydall, D.2
  • 86
    • 2042429168 scopus 로고    scopus 로고
    • Regulation of telomerase by telomeric proteins
    • DOI 10.1146/annurev.biochem.73.071403.160049
    • Smogorzewska, A. & T. de Lange: Regulation of telomerase by telomeric proteins. Annu Rev Biochem, 73, 177-208 (2004). (Pubitemid 39050367)
    • (2004) Annual Review of Biochemistry , vol.73 , pp. 177-208
    • Smogorzewska, A.1    De Lange, T.2
  • 87
    • 0038451396 scopus 로고    scopus 로고
    • POT1 as a terminal transducer of TRF1 telomere length control
    • DOI 10.1038/nature01688
    • Loayza, D. & T. De Lange: POT1 as a terminal transducer of TRF1 telomere length control. Nature, 423(6943), 1013-8 (2003). (Pubitemid 36806919)
    • (2003) Nature , vol.423 , Issue.6943 , pp. 1013-1018
    • Loayza, D.1    De Lange, T.2
  • 88
    • 70350435815 scopus 로고    scopus 로고
    • POT1 association with TRF2 regulates telomere length
    • Kendellen, M. F., K. S. Barrientos & C. M. Counter: POT1 association with TRF2 regulates telomere length. Mol Cell Biol, 29(20), 5611-9 (2009).
    • (2009) Mol Cell Biol , vol.29 , Issue.20 , pp. 5611-5619
    • Kendellen, M.F.1    Barrientos, K.S.2    Counter, C.M.3
  • 90
    • 33846691378 scopus 로고    scopus 로고
    • The POT1-TPP1 telomere complex is a telomerase processivity factor
    • DOI 10.1038/nature05454, PII NATURE05454
    • Wang, F., E. R. Podell, A. J. Zaug, Y. Yang, P. Baciu, T. R. Cech & M. Lei: The POT1-TPP1 telomere complex is a telomerase processivity factor. Nature, 445(7127), 506-10 (2007). (Pubitemid 46197626)
    • (2007) Nature , vol.445 , Issue.7127 , pp. 506-510
    • Wang, F.1    Podell, E.R.2    Zaug, A.J.3    Yang, Y.4    Baciu, P.5    Cech, T.R.6    Lei, M.7
  • 91
    • 33846692105 scopus 로고    scopus 로고
    • TPP1 is a homologue of ciliate TEBP-β and interacts with POT1 to recruit telomerase
    • DOI 10.1038/nature05469, PII NATURE05469
    • Xin, H., D. Liu, M. Wan, A. Safari, H. Kim, W. Sun, M. S. O'Connor & Z. Songyang: TPP1 is a homologue of ciliate TEBP-β and interacts with POT1 to recruit telomerase. Nature, 445(7127), 559-62 (2007). (Pubitemid 46197638)
    • (2007) Nature , vol.445 , Issue.7127 , pp. 559-562
    • Xin, H.1    Liu, D.2    Wan, M.3    Safari, A.4    Kim, H.5    Sun, W.6    O'Connor, M.S.7    Songyang, Z.8
  • 92
    • 70149121335 scopus 로고    scopus 로고
    • Fission yeast Tel1ATM and Rad3ATR promote telomere protection and telomerase recruitment
    • Moser, B. A., L. Subramanian, L. Khair, Y. T. Chang & T. M. Nakamura: Fission yeast Tel1ATM and Rad3ATR promote telomere protection and telomerase recruitment. PLoS Genet, 5(8), e1000622 (2009).
    • (2009) PLoS Genet , vol.5 , Issue.8
    • Moser, B.A.1    Subramanian, L.2    Khair, L.3    Chang, Y.T.4    Nakamura, T.M.5
  • 93
    • 55449131136 scopus 로고    scopus 로고
    • Two pathways recruit telomerase to Saccharomyces cerevisiae telomeres
    • Chan, A., J. B. Boule & V. A. Zakian: Two pathways recruit telomerase to Saccharomyces cerevisiae telomeres. PLoS Genet, 4(10), e1000236 (2008).
    • (2008) PLoS Genet , vol.4 , Issue.10
    • Chan, A.1    Boule, J.B.2    Zakian, V.A.3
  • 94
    • 0033214013 scopus 로고    scopus 로고
    • Est1 and Cdc13 as comediators of telomerase access
    • DOI 10.1126/science.286.5437.117
    • Evans, S. K. & V. Lundblad: Est1 and Cdc13 as comediators of telomerase access. Science, 286(5437), 117-20 (1999). (Pubitemid 29484489)
    • (1999) Science , vol.286 , Issue.5437 , pp. 117-120
    • Evans, S.K.1    Lundblad, V.2
  • 95
    • 0035830494 scopus 로고    scopus 로고
    • Cdc13 delivers separate complexes to the telomere for end protection and replication
    • DOI 10.1016/S0092-8674(01)00226-4
    • Pennock, E., K. Buckley & V. Lundblad: Cdc13 delivers separate complexes to the telomere for end protection and replication. Cell, 104(3), 387-96 (2001). (Pubitemid 32206459)
    • (2001) Cell , vol.104 , Issue.3 , pp. 387-396
    • Pennock, E.1    Buckley, K.2    Lundblad, V.3
  • 96
    • 6344284126 scopus 로고    scopus 로고
    • Fission yeast Dna2 is required for generation of the telomeric single-strand overhang
    • DOI 10.1128/MCB.24.21.9557-9567.2004
    • Tomita, K., T. Kibe, H. Y. Kang, Y. S. Seo, M. Uritani, T. Ushimaru & M. Ueno: Fission yeast Dna2 is required for generation of the telomeric single-strand overhang. Mol Cell Biol, 24(21), 9557-67 (2004). (Pubitemid 39391691)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.21 , pp. 9557-9567
    • Tomita, K.1    Kibe, T.2    Kang, H.-Y.3    Seo, Y.-S.4    Uritani, M.5    Ushimaru, T.6    Ueno, M.7
  • 97
    • 0027509950 scopus 로고
    • 1-3 tails late in S phase
    • DOI 10.1016/0092-8674(93)90049-V
    • Wellinger, R. J., A. J. Wolf & V. A. Zakian: Saccharomyces telomeres acquire single-strand TG1-3 tails late in S phase. Cell, 72(1), 51-60 (1993). (Pubitemid 23029692)
    • (1993) Cell , vol.72 , Issue.1 , pp. 51-60
    • Wellinger, R.J.1    Wolf, A.J.2    Zakian, V.A.3
  • 98
    • 68049088928 scopus 로고    scopus 로고
    • Telomere extension occurs at most chromosome ends and is uncoupled from fill-in in human cancer cells
    • Zhao, Y., A. J. Sfeir, Y. Zou, C. M. Buseman, T. T. Chow, J. W. Shay & W. E. Wright: Telomere extension occurs at most chromosome ends and is uncoupled from fill-in in human cancer cells. Cell, 138(3), 463-75 (2009).
    • (2009) Cell , vol.138 , Issue.3 , pp. 463-475
    • Zhao, Y.1    Sfeir, A.J.2    Zou, Y.3    Buseman, C.M.4    Chow, T.T.5    Shay, J.W.6    Wright, W.E.7
  • 99
    • 2942644725 scopus 로고    scopus 로고
    • The generation of proper constitutive G-tails on yeast telomeres is dependent on the MRX complex
    • DOI 10.1101/gad.1199404
    • Larrivee, M., C. LeBel & R. J. Wellinger: The generation of proper constitutive G-tails on yeast telomeres is dependent on the MRX complex. Genes Dev, 18(12), 1391-6 (2004). (Pubitemid 38780626)
    • (2004) Genes and Development , vol.18 , Issue.12 , pp. 1391-1396
    • Larrivee, M.1    LeBel, C.2    Wellinger, R.J.3
  • 100
    • 0029953557 scopus 로고    scopus 로고
    • Evidence for a new step in telomere maintenance
    • DOI 10.1016/S0092-8674(00)81120-4
    • Wellinger, R. J., K. Ethier, P. Labrecque & V. A. Zakian: Evidence for a new step in telomere maintenance. Cell, 85(3), 423-33 (1996). (Pubitemid 26160713)
    • (1996) Cell , vol.85 , Issue.3 , pp. 423-433
    • Wellinger, R.J.1    Ethier, K.2    Labrecque, P.3    Zakian, V.A.4
  • 101
    • 67649653968 scopus 로고    scopus 로고
    • Multiple pathways regulate 3' overhang generation at S. Cerevisiae telomeres
    • Bonetti, D., M. Martina, M. Clerici, G. Lucchini & M. P. Longhese: Multiple pathways regulate 3' overhang generation at S. cerevisiae telomeres. Mol Cell, 35(1), 70-81 (2009).
    • (2009) Mol Cell , vol.35 , Issue.1 , pp. 70-81
    • Bonetti, D.1    Martina, M.2    Clerici, M.3    Lucchini, G.4    Longhese, M.P.5
  • 103
    • 13944265075 scopus 로고    scopus 로고
    • Late S phase-specific recruitment of Mre11 complex triggers hierarchical assembly of telomere replication proteins in Saccharomyces cerevisiae
    • DOI 10.1016/j.molcel.2005.01.014
    • Takata, H., Y. Tanaka & A. Matsuura: Late S phase-specific recruitment of Mre11 complex triggers hierarchical assembly of telomere replication proteins in Saccharomyces cerevisiae. Mol Cell, 17(4), 573-83 (2005). (Pubitemid 40269121)
    • (2005) Molecular Cell , vol.17 , Issue.4 , pp. 573-583
    • Takata, H.1    Tanaka, Y.2    Matsuura, A.3
  • 104
    • 33750801681 scopus 로고    scopus 로고
    • The DNA Damage Machinery and Homologous Recombination Pathway Act Consecutively to Protect Human Telomeres
    • DOI 10.1016/j.cell.2006.09.034, PII S0092867406012943
    • Verdun, R. E. & J. Karlseder: The DNA damage machinery and homologous recombination pathway act consecutively to protect human telomeres. Cell, 127(4), 709-20 (2006). (Pubitemid 44716251)
    • (2006) Cell , vol.127 , Issue.4 , pp. 709-720
    • Verdun, R.E.1    Karlseder, J.2
  • 105
    • 31944436260 scopus 로고    scopus 로고
    • Cell cycle-dependent recruitment of telomerase RNA and cajal bodies to human telomeres
    • DOI 10.1091/mbc.E05-09-0904
    • Jady, B. E., P. Richard, E. Bertrand & T. Kiss: Cell cycle-dependent recruitment of telomerase RNA and Cajal bodies to human telomeres. Mol Biol Cell, 17(2), 944-54 (2006). (Pubitemid 43191126)
    • (2006) Molecular Biology of the Cell , vol.17 , Issue.2 , pp. 944-954
    • Jady, B.E.1    Richard, P.2    Bertrand, E.3    Kiss, T.4
  • 106
    • 34547731434 scopus 로고    scopus 로고
    • Telomerase and Tel1p Preferentially Associate with Short Telomeres in S. cerevisiae
    • DOI 10.1016/j.molcel.2007.07.016, PII S1097276507004893
    • Sabourin, M., C. T. Tuzon & V. A. Zakian: Telomerase and Tel1p preferentially associate with short telomeres in S. cerevisiae. Mol Cell, 27(4), 550-61 (2007). (Pubitemid 47238635)
    • (2007) Molecular Cell , vol.27 , Issue.4 , pp. 550-561
    • Sabourin, M.1    Tuzon, C.T.2    Zakian, V.A.3
  • 107
    • 31544466516 scopus 로고    scopus 로고
    • Human telomeres have different overhang sizes at leading versus lagging strands
    • DOI 10.1016/j.molcel.2005.12.004, PII S1097276505018460
    • Chai, W., Q. Du, J. W. Shay & W. E. Wright: Human telomeres have different overhang sizes at leading versus lagging strands. Mol Cell, 21(3), 427-35 (2006). (Pubitemid 43163537)
    • (2006) Molecular Cell , vol.21 , Issue.3 , pp. 427-435
    • Chai, W.1    Du, Q.2    Shay, J.W.3    Wright, W.E.4
  • 108
    • 0027944347 scopus 로고
    • TLC1: Template RNA component of Saccharomyces cerevisiae telomerase
    • Singer, M. S. & D. E. Gottschling: TLC1: template RNA component of Saccharomyces cerevisiae telomerase. Science, 266(5184), 404-9 (1994). (Pubitemid 24348957)
    • (1994) Science , vol.266 , Issue.5184 , pp. 404-409
    • Singer, M.S.1    Gottschling, D.E.2
  • 110
    • 24944578847 scopus 로고    scopus 로고
    • ATM and ATR make distinct contributions to chromosome end protection and the maintenance of telomeric DNA in Arabidopsis
    • DOI 10.1101/gad.1333805
    • Vespa, L., M. Couvillion, E. Spangler & D. E. Shippen: ATM and ATR make distinct contributions to chromosome end protection and the maintenance of telomeric DNA in Arabidopsis. Genes Dev, 19(18), 2111-5 (2005). (Pubitemid 41330313)
    • (2005) Genes and Development , vol.19 , Issue.18 , pp. 2111-2115
    • Vespa, L.1    Couvillion, M.2    Spangler, E.3    Shippen, D.E.4
  • 111
    • 59649089118 scopus 로고    scopus 로고
    • Telomere capping and cellular checkpoints: Clues from fruit flies
    • Ciapponi, L. & G. Cenci: Telomere capping and cellular checkpoints: clues from fruit flies. Cytogenet Genome Res, 122(3-4), 365-73 (2008).
    • (2008) Cytogenet Genome Res , vol.122 , Issue.3-4 , pp. 365-373
    • Ciapponi, L.1    Cenci, G.2
  • 112
    • 0034610290 scopus 로고    scopus 로고
    • Protein kinase activity of Tel1p and Mec1p, two Saccharomyces cerevisiae proteins related to the human ATM protein kinase
    • Mallory, J. C. & T. D. Petes: Protein kinase activity of Tel1p and Mec1p, two Saccharomyces cerevisiae proteins related to the human ATM protein kinase. Proc Natl Acad Sci U S A, 97(25), 13749-54 (2000).
    • (2000) Proc Natl Acad Sci U S A , vol.97 , Issue.25 , pp. 13749-13754
    • Mallory, J.C.1    Petes, T.D.2
  • 113
    • 0034642513 scopus 로고    scopus 로고
    • MRT-2 checkpoint protein is required for germline immortality and telomere replication in C. elegans
    • DOI 10.1038/35003120
    • Ahmed, S. & J. Hodgkin: MRT-2 checkpoint protein is required for germline immortality and telomere replication in C. elegans. Nature, 403(6766), 159-64 (2000). (Pubitemid 30050951)
    • (2000) Nature , vol.403 , Issue.6766 , pp. 159-164
    • Ahmed, S.1    Hodgkin, J.2
  • 114
    • 0037137445 scopus 로고    scopus 로고
    • Caenorhabditis elegans HUS-1 is a DNA damage checkpoint protein required for genome stability and EGL-1-mediated apoptosis
    • DOI 10.1016/S0960-9822(02)01262-9, PII S0960982202012629
    • Hofmann, E. R., S. Milstein, S. J. Boulton, M. Ye, J. J. Hofmann, L. Stergiou, A. Gartner, M. Vidal & M. O. Hengartner: Caenorhabditis elegans HUS-1 is a DNA damage checkpoint protein required for genome stability and EGL-1-mediated apoptosis. Curr Biol, 12(22), 1908-18 (2002). (Pubitemid 35426703)
    • (2002) Current Biology , vol.12 , Issue.22 , pp. 1908-1918
    • Hofmann, E.R.1    Milstein, S.2    Boulton, S.J.3    Ye, M.4    Hofmann, J.J.5    Stergiou, L.6    Gartner, A.7    Vidal, M.8    Hengartner, M.O.9
  • 115
    • 34548570360 scopus 로고    scopus 로고
    • The Caenorhabditis elegans Rad17 homolog HPR-17 is required for telomere replication
    • DOI 10.1534/genetics.106.070201
    • Boerckel, J., D. Walker & S. Ahmed: The Caenor-habditis elegans Rad17 homolog HPR-17 is required for telomere replication. Genetics, 176(1), 703-9 (2007). (Pubitemid 350021057)
    • (2007) Genetics , vol.176 , Issue.1 , pp. 703-709
    • Boerckel, J.1    Walker, D.2    Ahmed, S.3
  • 116
    • 33746569586 scopus 로고    scopus 로고
    • Telomere and Telomerase Modulation by the Mammalian Rad9/Rad1/Hus1 DNA-Damage-Checkpoint Complex
    • DOI 10.1016/j.cub.2006.06.066, PII S0960982206018458
    • Francia, S., R. S. Weiss, M. P. Hande, R. Freire & F. d'Adda di Fagagna: Telomere and telomerase modulation by the mammalian Rad9/Rad1/Hus1 DNA-damage-checkpoint complex. Curr Biol, 16(15), 1551-8 (2006). (Pubitemid 44142998)
    • (2006) Current Biology , vol.16 , Issue.15 , pp. 1551-1558
    • Francia, S.1    Weiss, R.S.2    Hande, M.P.3    Freire, R.4    D'Adda Di Fagagna, F.5
  • 118
    • 0036670615 scopus 로고    scopus 로고
    • Telomere binding of checkpoint sensor and DNA repair proteins contributes to maintenance of functional fission yeast telomeres
    • Nakamura, T. M., B. A. Moser & P. Russell: Telomere binding of checkpoint sensor and DNA repair proteins contributes to maintenance of functional fission yeast telomeres. Genetics, 161(4), 1437-52 (2002). (Pubitemid 35014747)
    • (2002) Genetics , vol.161 , Issue.4 , pp. 1437-1452
    • Nakamura, T.M.1    Moser, B.A.2    Russell, P.3
  • 119
    • 0033870408 scopus 로고    scopus 로고
    • Checkpoint proteins influence telomeric silencing and length maintenance in budding yeast
    • Longhese, M. P., V. Paciotti, H. Neecke & G. Lucchini: Checkpoint proteins influence telomeric silencing and length maintenance in budding yeast. Genetics, 155(4), 1577-91 (2000). (Pubitemid 30626380)
    • (2000) Genetics , vol.155 , Issue.4 , pp. 1577-1591
    • Longhese, M.P.1    Paciotti, V.2    Neecke, H.3    Lucchini, G.4
  • 120
    • 33845669591 scopus 로고    scopus 로고
    • The telomerase-recruitment domain of the telomere binding protein Cdc13 is regulated by Mec1p/Tel1p-dependent phosphorylation
    • Tseng, S. F., J. J. Lin & S. C. Teng: The telomerase-recruitment domain of the telomere binding protein Cdc13 is regulated by Mec1p/Tel1p-dependent phosphorylation. Nucleic Acids Res, 34(21), 6327-36 (2006).
    • (2006) Nucleic Acids Res , vol.34 , Issue.21 , pp. 6327-6336
    • Tseng, S.F.1    Lin, J.J.2    Teng, S.C.3
  • 121
    • 0035928740 scopus 로고    scopus 로고
    • Altering telomere structure allows telomerase to act in yeast lacking ATM kinases
    • DOI 10.1016/S0960-9822(01)00391-8
    • Chan, S. W., J. Chang, J. Prescott & E. H. Blackburn: Altering telomere structure allows telomerase to act in yeast lacking ATM kinases. Curr Biol, 11(16), 1240-50 (2001). (Pubitemid 32774080)
    • (2001) Current Biology , vol.11 , Issue.16 , pp. 1240-1250
    • Chan, S.W.L.1    Chang, J.2    Prescott, J.3    Blackburn, E.H.4
  • 122
    • 34548492016 scopus 로고    scopus 로고
    • MRE11-RAD50-NBS1 and ATM function as co-mediators of TRF1 in telomere length control
    • DOI 10.1038/nsmb1286, PII NSMB1286
    • Wu, Y., S. Xiao & X. D. Zhu: MRE11-RAD50-NBS1 and ATM function as co-mediators of TRF1 in telomere length control. Nat Struct Mol Biol, 14(9), 832-40 (2007). (Pubitemid 47373833)
    • (2007) Nature Structural and Molecular Biology , vol.14 , Issue.9 , pp. 832-840
    • Wu, Y.1    Xiao, S.2    Zhu, X.-D.3
  • 123
    • 51949118680 scopus 로고    scopus 로고
    • Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response
    • Morin, I., H. P. Ngo, A. Greenall, M. K. Zubko, N. Morrice & D. Lydall: Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response. EMBO J, 27(18), 2400-10 (2008).
    • (2008) EMBO J , vol.27 , Issue.18 , pp. 2400-2410
    • Morin, I.1    Ngo, H.P.2    Greenall, A.3    Zubko, M.K.4    Morrice, N.5    Lydall, D.6
  • 124
    • 70449522305 scopus 로고    scopus 로고
    • DNA damage signalling prevents deleterious telomere addition at DNA breaks
    • Makovets, S. & E. H. Blackburn: DNA damage signalling prevents deleterious telomere addition at DNA breaks. Nat Cell Biol, 11(11), 1383-6 (2009).
    • (2009) Nat Cell Biol , vol.11 , Issue.11 , pp. 1383-1386
    • Makovets, S.1    Blackburn, E.H.2
  • 125
    • 59649083955 scopus 로고    scopus 로고
    • Rif1 and rif2 inhibit localization of tel1 to DNA ends
    • Hirano, Y., K. Fukunaga & K. Sugimoto: Rif1 and rif2 inhibit localization of tel1 to DNA ends. Mol Cell, 33(3), 312-22 (2009).
    • (2009) Mol Cell , vol.33 , Issue.3 , pp. 312-322
    • Hirano, Y.1    Fukunaga, K.2    Sugimoto, K.3
  • 126
    • 0034013797 scopus 로고    scopus 로고
    • The Mre11p/Rad50p/Xrs2p complex and the Tellp function in a single pathway for telomere maintenance in yeast
    • Ritchie, K. B. & T. D. Petes: The Mre11p/Rad50p/Xrs2p complex and the Tel1p function in a single pathway for telomere maintenance in yeast. Genetics, 155(1), 475-9 (2000). (Pubitemid 30257144)
    • (2000) Genetics , vol.155 , Issue.1 , pp. 475-479
    • Ritchie, K.B.1    Petes, T.D.2
  • 127
    • 0041660970 scopus 로고    scopus 로고
    • ATM-related Tel1 associates with double-strand breaks through an Xrs2-dependent mechanism
    • DOI 10.1101/gad.1099003
    • Nakada, D., K. Matsumoto & K. Sugimoto: ATM-related Tel1 associates with double-strand breaks through an Xrs2-dependent mechanism. Genes Dev, 17(16), 1957-62 (2003). (Pubitemid 36999322)
    • (2003) Genes and Development , vol.17 , Issue.16 , pp. 1957-1962
    • Nakada, D.1    Matsumoto, K.2    Sugimoto, K.3
  • 128
    • 34447532519 scopus 로고    scopus 로고
    • Increased association of telomerase with short telomeres in yeast
    • DOI 10.1101/gad.438907
    • Bianchi, A. & D. Shore: Increased association of telomerase with short telomeres in yeast. Genes Dev, 21(14), 1726-30 (2007). (Pubitemid 47076472)
    • (2007) Genes and Development , vol.21 , Issue.14 , pp. 1726-1730
    • Bianchi, A.1    Shore, D.2
  • 129
    • 34547813672 scopus 로고    scopus 로고
    • S. cerevisiae Tel1p and Mre11p are required for normal levels of Est1p and Est2p telomere association
    • DOI 10.1016/j.molcel.2006.10.005
    • Goudsouzian, L. K., C. T. Tuzon & V. A. Zakian: S. cerevisiae Tel1p and Mre11p are required for normal levels of Est1p and Est2p telomere association. Mol Cell, 24(4), 603-10 (2006). (Pubitemid 350284226)
    • (2006) Molecular Cell , vol.24 , Issue.4 , pp. 603-610
    • Goudsouzian, L.K.1    Tuzon, C.T.2    Zakian, V.A.3
  • 130
    • 70249120364 scopus 로고    scopus 로고
    • Kinase-independent functions of TEL1 in telomere maintenance
    • Ma, Y. & C. W. Greider: Kinase-independent functions of TEL1 in telomere maintenance. Mol Cell Biol, 29(18), 5193-202 (2009).
    • (2009) Mol Cell Biol , vol.29 , Issue.18 , pp. 5193-5202
    • Ma, Y.1    Greider, C.W.2
  • 131
    • 77649225618 scopus 로고    scopus 로고
    • ATRIP complex in recruitment of Tel1ATM to telomeres in fission yeast
    • ATRIP complex in recruitment of Tel1ATM to telomeres in fission yeast. PLoS Genet, 6(2), e1000839 (2010).
    • (2010) PLoS Genet , vol.6 , Issue.2
    • Subramanian, L.1    Nakamura, T.M.2
  • 132
    • 33645800789 scopus 로고    scopus 로고
    • The involvement of the Mre11/Rad50/Nbs1 complex in the generation of G-overhangs at human telomeres
    • Chai, W., A. J. Sfeir, H. Hoshiyama, J. W. Shay & W. E. Wright: The involvement of the Mre11/Rad50/Nbs1 complex in the generation of G-overhangs at human telomeres. EMBO Rep, 7(2), 225-30 (2006).
    • (2006) EMBO Rep , vol.7 , Issue.2 , pp. 225-230
    • Chai, W.1    Sfeir, A.J.2    Hoshiyama, H.3    Shay, J.W.4    Wright, W.E.5
  • 133
    • 33749534161 scopus 로고    scopus 로고
    • Telomeres and telomerase: The path from maize, Tetrahymena and yeast to human cancer and aging
    • DOI 10.1038/nm1006-1133, PII NM10061133
    • Blackburn, E. H., C. W. Greider & J. W. Szostak: Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging. Nat Med, 12(10), 1133-8 (2006). (Pubitemid 44527346)
    • (2006) Nature Medicine , vol.12 , Issue.10 , pp. 1133-1138
    • Blackburn, E.H.1    Greider, C.W.2    Szostak, J.W.3
  • 134
    • 69949085736 scopus 로고    scopus 로고
    • Telomeres and disease
    • Lansdorp, P. M.: Telomeres and disease. EMBO J, 28(17), 2532-40 (2009).
    • (2009) EMBO J , vol.28 , Issue.17 , pp. 2532-2540
    • Lansdorp, P.M.1
  • 135
    • 22944488871 scopus 로고    scopus 로고
    • Telomeres and human disease: Ageing, cancer and beyond
    • DOI 10.1038/nrg1656
    • Blasco, M. A.: Telomeres and human disease: ageing, cancer and beyond. Nat Rev Genet, 6(8), 611-22 (2005). (Pubitemid 41044298)
    • (2005) Nature Reviews Genetics , vol.6 , Issue.8 , pp. 611-622
    • Blasco, M.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.