메뉴 건너뛰기




Volumn 35, Issue 1, 2009, Pages 70-81

Multiple Pathways Regulate 3′ Overhang Generation at S. cerevisiae Telomeres

Author keywords

DNA

Indexed keywords

EXONUCLEASE; RECQ HELICASE;

EID: 67649653968     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2009.05.015     Document Type: Article
Times cited : (106)

References (50)
  • 1
    • 11244269445 scopus 로고    scopus 로고
    • The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle
    • Aylon Y., Liefshitz B., and Kupiec M. The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle. EMBO J. 23 (2004) 4868-4875
    • (2004) EMBO J. , vol.23 , pp. 4868-4875
    • Aylon, Y.1    Liefshitz, B.2    Kupiec, M.3
  • 2
    • 0035954737 scopus 로고    scopus 로고
    • RPA governs endonuclease switching during processing of Okazaki fragments in eukaryotes
    • Bae S.H., Bae K.H., Kim J.A., and Seo Y.S. RPA governs endonuclease switching during processing of Okazaki fragments in eukaryotes. Nature 412 (2001) 456-461
    • (2001) Nature , vol.412 , pp. 456-461
    • Bae, S.H.1    Bae, K.H.2    Kim, J.A.3    Seo, Y.S.4
  • 3
    • 2442520305 scopus 로고    scopus 로고
    • EXO1 contributes to telomere maintenance in both telomerase-proficient and telomerase-deficient Saccharomyces cerevisiae
    • Bertuch A.A., and Lundblad V. EXO1 contributes to telomere maintenance in both telomerase-proficient and telomerase-deficient Saccharomyces cerevisiae. Genetics 166 (2004) 1651-1659
    • (2004) Genetics , vol.166 , pp. 1651-1659
    • Bertuch, A.A.1    Lundblad, V.2
  • 4
    • 4944265507 scopus 로고    scopus 로고
    • Delivery of yeast telomerase to a DNA break depends on the recruitment functions of Cdc13 and Est1
    • Bianchi A., Negrini S., and Shore D. Delivery of yeast telomerase to a DNA break depends on the recruitment functions of Cdc13 and Est1. Mol. Cell 16 (2004) 139-146
    • (2004) Mol. Cell , vol.16 , pp. 139-146
    • Bianchi, A.1    Negrini, S.2    Shore, D.3
  • 5
    • 0034596053 scopus 로고    scopus 로고
    • The nuclease activity of the yeast DNA2 protein, which is related to the RecB-like nuclease, is essential in vivo
    • Budd M.E., Choe W., and Campbell J.L. The nuclease activity of the yeast DNA2 protein, which is related to the RecB-like nuclease, is essential in vivo. J. Biol. Chem. 275 (2000) 16518-16529
    • (2000) J. Biol. Chem. , vol.275 , pp. 16518-16529
    • Budd, M.E.1    Choe, W.2    Campbell, J.L.3
  • 6
    • 33645215616 scopus 로고    scopus 로고
    • Evidence suggesting that Pif1 helicase functions in DNA replication with the Dna2 helicase/nuclease and DNA polymerase δ
    • Budd M.E., Reis C.C., Smith S., Myung K., and Campbell J.L. Evidence suggesting that Pif1 helicase functions in DNA replication with the Dna2 helicase/nuclease and DNA polymerase δ. Mol. Cell. Biol. 26 (2006) 2490-2500
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 2490-2500
    • Budd, M.E.1    Reis, C.C.2    Smith, S.3    Myung, K.4    Campbell, J.L.5
  • 7
    • 33749603235 scopus 로고    scopus 로고
    • A network of multi-tasking proteins at the DNA replication fork preserves genome stability
    • Budd M.E., Tong A.H., Polaczek P., Peng X., Boone C., and Campbell J.L. A network of multi-tasking proteins at the DNA replication fork preserves genome stability. PLoS Genet. 1 (2005) e61
    • (2005) PLoS Genet. , vol.1
    • Budd, M.E.1    Tong, A.H.2    Polaczek, P.3    Peng, X.4    Boone, C.5    Campbell, J.L.6
  • 8
    • 0022387528 scopus 로고
    • CDC17: an essential gene that prevents telomere elongation in yeast
    • Carson M.J., and Hartwell L. CDC17: an essential gene that prevents telomere elongation in yeast. Cell 42 (1985) 249-257
    • (1985) Cell , vol.42 , pp. 249-257
    • Carson, M.J.1    Hartwell, L.2
  • 9
    • 33645800789 scopus 로고    scopus 로고
    • The involvement of the Mre11/Rad50/Nbs1 complex in the generation of G-overhangs at human telomeres
    • Chai W., Sfeir A.J., Hoshiyama H., Shay J.W., and Wright W.E. The involvement of the Mre11/Rad50/Nbs1 complex in the generation of G-overhangs at human telomeres. EMBO Rep. 7 (2006) 225-230
    • (2006) EMBO Rep. , vol.7 , pp. 225-230
    • Chai, W.1    Sfeir, A.J.2    Hoshiyama, H.3    Shay, J.W.4    Wright, W.E.5
  • 10
    • 33644691699 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends
    • Clerici M., Mantiero D., Lucchini G., and Longhese M.P. The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends. J. Biol. Chem. 280 (2005) 38631-38638
    • (2005) J. Biol. Chem. , vol.280 , pp. 38631-38638
    • Clerici, M.1    Mantiero, D.2    Lucchini, G.3    Longhese, M.P.4
  • 11
    • 33645799075 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae Sae2 protein negatively regulates DNA damage checkpoint signalling
    • Clerici M., Mantiero D., Lucchini G., and Longhese M.P. The Saccharomyces cerevisiae Sae2 protein negatively regulates DNA damage checkpoint signalling. EMBO Rep. 7 (2006) 212-218
    • (2006) EMBO Rep. , vol.7 , pp. 212-218
    • Clerici, M.1    Mantiero, D.2    Lucchini, G.3    Longhese, M.P.4
  • 13
    • 0035806955 scopus 로고    scopus 로고
    • Exonuclease activity is required for sequence addition and Cdc13p loading at a de novo telomere
    • Diede S.J., and Gottschling D.E. Exonuclease activity is required for sequence addition and Cdc13p loading at a de novo telomere. Curr. Biol. 11 (2001) 1336-1340
    • (2001) Curr. Biol. , vol.11 , pp. 1336-1340
    • Diede, S.J.1    Gottschling, D.E.2
  • 14
    • 0030460748 scopus 로고    scopus 로고
    • Cell cycle-regulated generation of single-stranded G-rich DNA in the absence of telomerase
    • Dionne I., and Wellinger R.J. Cell cycle-regulated generation of single-stranded G-rich DNA in the absence of telomerase. Proc. Natl. Acad. Sci. USA 93 (1996) 13902-13907
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 13902-13907
    • Dionne, I.1    Wellinger, R.J.2
  • 15
    • 33750431337 scopus 로고    scopus 로고
    • Regulation of telomere elongation by the cyclin-dependent kinase CDK1
    • Frank C.J., Hyde M., and Greider C.W. Regulation of telomere elongation by the cyclin-dependent kinase CDK1. Mol. Cell 24 (2006) 423-432
    • (2006) Mol. Cell , vol.24 , pp. 423-432
    • Frank, C.J.1    Hyde, M.2    Greider, C.W.3
  • 16
    • 34547813672 scopus 로고    scopus 로고
    • S. cerevisiae Tel1p and Mre11p are required for normal levels of Est1p and Est2p telomere association
    • Goudsouzian L.K., Tuzon C.T., and Zakian V.A. S. cerevisiae Tel1p and Mre11p are required for normal levels of Est1p and Est2p telomere association. Mol. Cell 24 (2006) 603-610
    • (2006) Mol. Cell , vol.24 , pp. 603-610
    • Goudsouzian, L.K.1    Tuzon, C.T.2    Zakian, V.A.3
  • 17
    • 53649090109 scopus 로고    scopus 로고
    • DNA helicases Sgs1 and BLM promote DNA double-strand break resection
    • Gravel S., Chapman J.R., Magill C., and Jackson S.P. DNA helicases Sgs1 and BLM promote DNA double-strand break resection. Genes Dev. 22 (2008) 2767-2772
    • (2008) Genes Dev. , vol.22 , pp. 2767-2772
    • Gravel, S.1    Chapman, J.R.2    Magill, C.3    Jackson, S.P.4
  • 18
    • 0024573115 scopus 로고
    • An overhanging 3′ terminus is a conserved feature of telomeres
    • Henderson E.R., and Blackburn E.H. An overhanging 3′ terminus is a conserved feature of telomeres. Mol. Cell. Biol. 9 (1989) 345-348
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 345-348
    • Henderson, E.R.1    Blackburn, E.H.2
  • 20
    • 53349162987 scopus 로고    scopus 로고
    • CDK targets Sae2 to control DNA-end resection and homologous recombination
    • Huertas P., Cortés-Ledesma F., Sartori A.A., Aguilera A., and Jackson S.P. CDK targets Sae2 to control DNA-end resection and homologous recombination. Nature 455 (2008) 689-692
    • (2008) Nature , vol.455 , pp. 689-692
    • Huertas, P.1    Cortés-Ledesma, F.2    Sartori, A.A.3    Aguilera, A.4    Jackson, S.P.5
  • 22
    • 2942644725 scopus 로고    scopus 로고
    • The generation of proper constitutive G-tails on yeast telomeres is dependent on the MRX complex
    • Larrivée M., LeBel C., and Wellinger R.J. The generation of proper constitutive G-tails on yeast telomeres is dependent on the MRX complex. Genes Dev. 18 (2004) 1391-1396
    • (2004) Genes Dev. , vol.18 , pp. 1391-1396
    • Larrivée, M.1    LeBel, C.2    Wellinger, R.J.3
  • 24
    • 34250333895 scopus 로고    scopus 로고
    • Evidence that a RecQ helicase slows senescence by resolving recombining telomeres
    • Lee J.Y., Kozak M., Martin J.D., Pennock E., and Johnson F.B. Evidence that a RecQ helicase slows senescence by resolving recombining telomeres. PLoS Biol. 5 (2007) e160
    • (2007) PLoS Biol. , vol.5
    • Lee, J.Y.1    Kozak, M.2    Martin, J.D.3    Pennock, E.4    Johnson, F.B.5
  • 25
    • 36248942617 scopus 로고    scopus 로고
    • Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex
    • Lengsfeld B.M., Rattray A.J., Bhaskara V., Ghirlando R., and Paull T.T. Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex. Mol. Cell 28 (2007) 638-651
    • (2007) Mol. Cell , vol.28 , pp. 638-651
    • Lengsfeld, B.M.1    Rattray, A.J.2    Bhaskara, V.3    Ghirlando, R.4    Paull, T.T.5
  • 26
    • 58149094903 scopus 로고    scopus 로고
    • Cdk1-dependent phosphorylation of Cdc13 coordinates telomere elongation during cell-cycle progression
    • Li S., Makovets S., Matsuguchi T., Blethrow J.D., Shokat K.M., and Blackburn E.H. Cdk1-dependent phosphorylation of Cdc13 coordinates telomere elongation during cell-cycle progression. Cell 136 (2009) 50-61
    • (2009) Cell , vol.136 , pp. 50-61
    • Li, S.1    Makovets, S.2    Matsuguchi, T.3    Blethrow, J.D.4    Shokat, K.M.5    Blackburn, E.H.6
  • 27
    • 34948872046 scopus 로고    scopus 로고
    • Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination
    • Limbo O., Chahwan C., Yamada Y., de Bruin R.A., Wittenberg C., and Russell P. Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination. Mol. Cell 28 (2007) 134-146
    • (2007) Mol. Cell , vol.28 , pp. 134-146
    • Limbo, O.1    Chahwan, C.2    Yamada, Y.3    de Bruin, R.A.4    Wittenberg, C.5    Russell, P.6
  • 28
    • 6344254299 scopus 로고    scopus 로고
    • The Mre11 nuclease is not required for 5′ to 3′ resection at multiple HO-induced double-strand breaks
    • Llorente B., and Symington L.S. The Mre11 nuclease is not required for 5′ to 3′ resection at multiple HO-induced double-strand breaks. Mol. Cell. Biol. 24 (2004) 9682-9694
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 9682-9694
    • Llorente, B.1    Symington, L.S.2
  • 29
    • 38349073475 scopus 로고    scopus 로고
    • DNA damage response at functional and dysfunctional telomeres
    • Longhese M.P. DNA damage response at functional and dysfunctional telomeres. Genes Dev. 22 (2008) 125-140
    • (2008) Genes Dev. , vol.22 , pp. 125-140
    • Longhese, M.P.1
  • 30
    • 0031000884 scopus 로고    scopus 로고
    • Long G tails at both ends of human chromosomes suggest a C-strand degradation mechanism for telomere shortening
    • Makarov V.L., Hirose Y., and Langmore J.P. Long G tails at both ends of human chromosomes suggest a C-strand degradation mechanism for telomere shortening. Cell 88 (1997) 657-666
    • (1997) Cell , vol.88 , pp. 657-666
    • Makarov, V.L.1    Hirose, Y.2    Langmore, J.P.3
  • 31
    • 34047102946 scopus 로고    scopus 로고
    • Dual role for Saccharomyces cerevisiae Tel1 in the checkpoint response to double-strand breaks
    • Mantiero D., Clerici M., Lucchini G., and Longhese M.P. Dual role for Saccharomyces cerevisiae Tel1 in the checkpoint response to double-strand breaks. EMBO Rep. 8 (2007) 380-387
    • (2007) EMBO Rep. , vol.8 , pp. 380-387
    • Mantiero, D.1    Clerici, M.2    Lucchini, G.3    Longhese, M.P.4
  • 32
    • 0033564210 scopus 로고    scopus 로고
    • Progressive cis-inhibition of telomerase upon telomere elongation
    • Marcand S., Brevet V., and Gilson E. Progressive cis-inhibition of telomerase upon telomere elongation. EMBO J. 18 (1999) 3509-3519
    • (1999) EMBO J. , vol.18 , pp. 3509-3519
    • Marcand, S.1    Brevet, V.2    Gilson, E.3
  • 33
    • 0034175814 scopus 로고    scopus 로고
    • Cell cycle restriction of telomere elongation
    • Marcand S., Brevet V., Mann C., and Gilson E. Cell cycle restriction of telomere elongation. Curr. Biol. 10 (2000) 487-490
    • (2000) Curr. Biol. , vol.10 , pp. 487-490
    • Marcand, S.1    Brevet, V.2    Mann, C.3    Gilson, E.4
  • 34
    • 0036682516 scopus 로고    scopus 로고
    • EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Δ mutants
    • Maringele L., and Lydall D. EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Δ mutants. Genes Dev. 16 (2002) 1919-1933
    • (2002) Genes Dev. , vol.16 , pp. 1919-1933
    • Maringele, L.1    Lydall, D.2
  • 35
    • 53649104599 scopus 로고    scopus 로고
    • Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing
    • Mimitou E.P., and Symington L.S. Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing. Nature 455 (2008) 770-774
    • (2008) Nature , vol.455 , pp. 770-774
    • Mimitou, E.P.1    Symington, L.S.2
  • 36
    • 23944459784 scopus 로고    scopus 로고
    • Endonucleolytic processing of covalent protein-linked DNA double-strand breaks
    • Neale M.J., Pan J., and Keeney S. Endonucleolytic processing of covalent protein-linked DNA double-strand breaks. Nature 436 (2005) 1053-1057
    • (2005) Nature , vol.436 , pp. 1053-1057
    • Neale, M.J.1    Pan, J.2    Keeney, S.3
  • 37
    • 33846970933 scopus 로고    scopus 로고
    • DNA breaks are masked by multiple Rap1 binding in yeast: implications for telomere capping and telomerase regulation
    • Negrini S., Ribaud V., Bianchi A., and Shore D. DNA breaks are masked by multiple Rap1 binding in yeast: implications for telomere capping and telomerase regulation. Genes Dev. 21 (2007) 292-302
    • (2007) Genes Dev. , vol.21 , pp. 292-302
    • Negrini, S.1    Ribaud, V.2    Bianchi, A.3    Shore, D.4
  • 38
    • 0035830494 scopus 로고    scopus 로고
    • Cdc13 delivers separate complexes to the telomere for end protection and replication
    • Pennock E., Buckley K., and Lundblad V. Cdc13 delivers separate complexes to the telomere for end protection and replication. Cell 104 (2001) 387-396
    • (2001) Cell , vol.104 , pp. 387-396
    • Pennock, E.1    Buckley, K.2    Lundblad, V.3
  • 40
    • 0028178792 scopus 로고
    • The Saccharomyces PIF1 DNA helicase inhibits telomere elongation and de novo telomere formation
    • Schulz V.P., and Zakian V.A. The Saccharomyces PIF1 DNA helicase inhibits telomere elongation and de novo telomere formation. Cell 76 (1994) 145-155
    • (1994) Cell , vol.76 , pp. 145-155
    • Schulz, V.P.1    Zakian, V.A.2
  • 41
    • 0034130841 scopus 로고    scopus 로고
    • EXO1 and MSH6 are high-copy suppressors of conditional mutations in the MSH2 mismatch repair gene of Saccharomyces cerevisiae
    • Sokolsky T., and Alani E. EXO1 and MSH6 are high-copy suppressors of conditional mutations in the MSH2 mismatch repair gene of Saccharomyces cerevisiae. Genetics 155 (2000) 589-599
    • (2000) Genetics , vol.155 , pp. 589-599
    • Sokolsky, T.1    Alani, E.2
  • 42
    • 0033135161 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae Sgs1 helicase efficiently unwinds G-G paired DNAs
    • Sun H., Bennett R.J., and Maizels N. The Saccharomyces cerevisiae Sgs1 helicase efficiently unwinds G-G paired DNAs. Nucleic Acids Res. 27 (1999) 1978-1984
    • (1999) Nucleic Acids Res. , vol.27 , pp. 1978-1984
    • Sun, H.1    Bennett, R.J.2    Maizels, N.3
  • 43
    • 6344284126 scopus 로고    scopus 로고
    • Fission yeast Dna2 is required for generation of the telomeric single-strand overhang
    • Tomita K., Kibe T., Kang H.Y., Seo Y.S., Uritani M., Ushimaru T., and Ueno M. Fission yeast Dna2 is required for generation of the telomeric single-strand overhang. Mol. Cell. Biol. 24 (2004) 9557-9567
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 9557-9567
    • Tomita, K.1    Kibe, T.2    Kang, H.Y.3    Seo, Y.S.4    Uritani, M.5    Ushimaru, T.6    Ueno, M.7
  • 44
    • 33845669591 scopus 로고    scopus 로고
    • The telomerase-recruitment domain of the telomere binding protein Cdc13 is regulated by Mec1p/Tel1p-dependent phosphorylation
    • Tseng S.F., Lin J.J., and Teng S.C. The telomerase-recruitment domain of the telomere binding protein Cdc13 is regulated by Mec1p/Tel1p-dependent phosphorylation. Nucleic Acids Res. 34 (2006) 6327-6336
    • (2006) Nucleic Acids Res. , vol.34 , pp. 6327-6336
    • Tseng, S.F.1    Lin, J.J.2    Teng, S.C.3
  • 45
    • 0035806977 scopus 로고    scopus 로고
    • The role of the Mre11-Rad50-Xrs2 complex in telomerase-mediated lengthening of Saccharomyces cerevisiae telomeres
    • Tsukamoto Y., Taggart A.K.P., and Zakian V.A. The role of the Mre11-Rad50-Xrs2 complex in telomerase-mediated lengthening of Saccharomyces cerevisiae telomeres. Curr. Biol. 11 (2001) 1328-1335
    • (2001) Curr. Biol. , vol.11 , pp. 1328-1335
    • Tsukamoto, Y.1    Taggart, A.K.P.2    Zakian, V.A.3
  • 46
    • 33749059184 scopus 로고    scopus 로고
    • DNA degradation at unprotected telomeres in yeast is regulated by the CDK1 (Cdc28/Clb) cell-cycle kinase
    • Vodenicharov M.D., and Wellinger R.J. DNA degradation at unprotected telomeres in yeast is regulated by the CDK1 (Cdc28/Clb) cell-cycle kinase. Mol. Cell 24 (2006) 127-137
    • (2006) Mol. Cell , vol.24 , pp. 127-137
    • Vodenicharov, M.D.1    Wellinger, R.J.2
  • 47
    • 0029953557 scopus 로고    scopus 로고
    • Evidence for a new step in telomere maintenance
    • Wellinger R.J., Ethier K., Labrecque P., and Zakian V.A. Evidence for a new step in telomere maintenance. Cell 85 (1996) 423-433
    • (1996) Cell , vol.85 , pp. 423-433
    • Wellinger, R.J.1    Ethier, K.2    Labrecque, P.3    Zakian, V.A.4
  • 48
    • 0027509950 scopus 로고
    • Saccharomyces telomeres acquire single-strand TG1-3 tails late in S phase
    • Wellinger R.J., Wolf A.J., and Zakian V.A. Saccharomyces telomeres acquire single-strand TG1-3 tails late in S phase. Cell 72 (1993) 51-60
    • (1993) Cell , vol.72 , pp. 51-60
    • Wellinger, R.J.1    Wolf, A.J.2    Zakian, V.A.3
  • 49
    • 0025877846 scopus 로고
    • Inhibition of telomerase by G-quartet DNA structures
    • Zahler A.M., Williamson J.R., Cech T.R., and Prescott D.M. Inhibition of telomerase by G-quartet DNA structures. Nature 350 (1991) 718-720
    • (1991) Nature , vol.350 , pp. 718-720
    • Zahler, A.M.1    Williamson, J.R.2    Cech, T.R.3    Prescott, D.M.4
  • 50
    • 51549095956 scopus 로고    scopus 로고
    • Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends
    • Zhu Z., Chung W.H., Shim E.Y., Lee S.E., and Ira G. Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends. Cell 134 (2008) 981-994
    • (2008) Cell , vol.134 , pp. 981-994
    • Zhu, Z.1    Chung, W.H.2    Shim, E.Y.3    Lee, S.E.4    Ira, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.