-
1
-
-
0035929353
-
Switching and signaling at the telomere
-
Blackburn, E. H. Switching and signaling at the telomere. Cell 106, 661-673 (2001).
-
(2001)
Cell
, vol.106
, pp. 661-673
-
-
Blackburn, E.H.1
-
2
-
-
0842346436
-
Beginning to understand the end of the chromosome
-
Cech, T. R. Beginning to understand the end of the chromosome. Cell 116, 273-279 (2004).
-
(2004)
Cell
, vol.116
, pp. 273-279
-
-
Cech, T.R.1
-
3
-
-
0036782884
-
Telomerase: A target for cancer therapeutics
-
Shay, J. W. & Wright, W. E. Telomerase: a target for cancer therapeutics. Cancer Cell 2, 257-265 (2002).
-
(2002)
Cancer Cell
, vol.2
, pp. 257-265
-
-
Shay, J.W.1
Wright, W.E.2
-
4
-
-
0029586089
-
A human telomeric protein
-
Chong, L. et al. A human telomeric protein. Science 270, 1663-1667 (1995).
-
(1995)
Science
, vol.270
, pp. 1663-1667
-
-
Chong, L.1
-
5
-
-
84984775429
-
Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2
-
Broccoli, D., Smogorzewska, A., Chong, L. & de Lange, T. Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2. Nature Genet. 17, 231-235 (1997).
-
(1997)
Nature Genet
, vol.17
, pp. 231-235
-
-
Broccoli, D.1
Smogorzewska, A.2
Chong, L.3
de Lange, T.4
-
6
-
-
0035844082
-
Pot1, the putative telomere end-binding protein in fission yeast and humans
-
Baumann, P. & Cech, T. R. Pot1, the putative telomere end-binding protein in fission yeast and humans. Science 292, 1171-1175 (2001).
-
(2001)
Science
, vol.292
, pp. 1171-1175
-
-
Baumann, P.1
Cech, T.R.2
-
7
-
-
0036840361
-
Human Pot1 (protection of telomeres) protein: Cytolocalization, gene structure, and alternative splicing
-
Baumann, P., Podell, E. & Cech, T. R. Human Pot1 (protection of telomeres) protein: cytolocalization, gene structure, and alternative splicing. Mol. Cell. Biol. 22, 8079-8087 (2002).
-
(2002)
Mol. Cell. Biol
, vol.22
, pp. 8079-8087
-
-
Baumann, P.1
Podell, E.2
Cech, T.R.3
-
8
-
-
33745685066
-
Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres
-
Hockemeyer, D., Daniels, J. P., Takai, H. & de Lange, T. Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres. Cell 126, 63-77 (2006).
-
(2006)
Cell
, vol.126
, pp. 63-77
-
-
Hockemeyer, D.1
Daniels, J.P.2
Takai, H.3
de Lange, T.4
-
9
-
-
33745713451
-
Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres
-
Wu, L. et al. Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres. Cell 126, 49-62 (2006).
-
(2006)
Cell
, vol.126
, pp. 49-62
-
-
Wu, L.1
-
10
-
-
12844265975
-
Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection
-
Lei, M., Podell, E. R. & Cech, T. R. Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection. Nature Struct. Mol. Biol. 11, 1223-1229 (2004).
-
(2004)
Nature Struct. Mol. Biol
, vol.11
, pp. 1223-1229
-
-
Lei, M.1
Podell, E.R.2
Cech, T.R.3
-
11
-
-
0038451396
-
POT1 as a terminal transducer of TRF1 telomere length control
-
Loayza, D. & de Lange, T. POT1 as a terminal transducer of TRF1 telomere length control. Nature 423, 1013-1018 (2003).
-
(2003)
Nature
, vol.423
, pp. 1013-1018
-
-
Loayza, D.1
de Lange, T.2
-
12
-
-
3142679378
-
POT1-interacting protein PIP1: A telomere length regulator that recruits POT1 to the TIN2/TRF1 complex
-
Ye, J. Z. et al. POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex. Genes Dev. 18, 1649-1654 (2004).
-
(2004)
Genes Dev
, vol.18
, pp. 1649-1654
-
-
Ye, J.Z.1
-
13
-
-
3242680818
-
PTOP interacts with POT1 and regulates its localization to telomeres
-
Liu, D. et al. PTOP interacts with POT1 and regulates its localization to telomeres. Nature Cell Biol. 6, 673-680 (2004).
-
(2004)
Nature Cell Biol
, vol.6
, pp. 673-680
-
-
Liu, D.1
-
14
-
-
4544258775
-
A dynamic molecular link between the telomere length regulator TRF1 and the chromosome end protector TRF2
-
Houghtaling, B. R., Cuttonaro, L., Chang, W. & Smith, S. A dynamic molecular link between the telomere length regulator TRF1 and the chromosome end protector TRF2. Curr. Biol. 14, 1621-1631 (2004).
-
(2004)
Curr. Biol
, vol.14
, pp. 1621-1631
-
-
Houghtaling, B.R.1
Cuttonaro, L.2
Chang, W.3
Smith, S.4
-
15
-
-
0032727616
-
TIN2, a new regulator of telomere length in human cells
-
Kim, S. H., Kaminker, P. & Campisi, J. TIN2, a new regulator of telomere length in human cells. Nature Genet. 23, 405-412 (1999).
-
(1999)
Nature Genet
, vol.23
, pp. 405-412
-
-
Kim, S.H.1
Kaminker, P.2
Campisi, J.3
-
16
-
-
10944240539
-
Telosome, a mammalian telomereassociated complex formed by multiple telomeric proteins
-
Liu, D. O'connor, M. S., Qin, J. & Songyang, Z. Telosome, a mammalian telomereassociated complex formed by multiple telomeric proteins. J. Biol. Chem. 279, 51338-51342 (2004).
-
(2004)
J. Biol. Chem
, vol.279
, pp. 51338-51342
-
-
Liu, D.1
O'connor, M.S.2
Qin, J.3
Songyang, Z.4
-
17
-
-
6944232071
-
TIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeres
-
Ye, J. Z. et al. TIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeres. J. Biol. Chem. 279, 47264-47271 (2004).
-
(2004)
J. Biol. Chem
, vol.279
, pp. 47264-47271
-
-
Ye, J.Z.1
-
18
-
-
33747051742
-
A critical role for TPP1 and TIN2 interaction in high-order telomeric complex assembly
-
O'Connor, M. S., Safari, A., Xin, H., Liu, D. & Songyang, Z. A critical role for TPP1 and TIN2 interaction in high-order telomeric complex assembly. Proc. Natl Acad. Sci. USA 103, 11874-11879 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 11874-11879
-
-
O'Connor, M.S.1
Safari, A.2
Xin, H.3
Liu, D.4
Songyang, Z.5
-
19
-
-
6344289975
-
TIN2 mediates functions of TRF2 at human telomeres
-
Kim, S. H. et al. TIN2 mediates functions of TRF2 at human telomeres. J. Biol. Chem. 279, 43799-43804 (2004).
-
(2004)
J. Biol. Chem
, vol.279
, pp. 43799-43804
-
-
Kim, S.H.1
-
20
-
-
0034716904
-
Identification of human Rap1: Implications for telomere evolution
-
Li, B., Oestreich, S. & de Lange, T. Identification of human Rap1: implications for telomere evolution. Cell 101, 471-483 (2000).
-
(2000)
Cell
, vol.101
, pp. 471-483
-
-
Li, B.1
Oestreich, S.2
de Lange, T.3
-
21
-
-
24944460598
-
Shelterin: The protein complex that shapes and safeguards human telomeres
-
de Lange, T. Shelterin: the protein complex that shapes and safeguards human telomeres. Genes Dev. 19, 2100-2110 (2005).
-
(2005)
Genes Dev
, vol.19
, pp. 2100-2110
-
-
de Lange, T.1
-
22
-
-
0025181674
-
Two versions of the gene encoding the 41-kilodalton subunit of the telomere binding protein of Oxytricha nova
-
Hicke, B. J., Celander, D. W., MacDonald, G. H., Price, C. M. & Cech, T. R. Two versions of the gene encoding the 41-kilodalton subunit of the telomere binding protein of Oxytricha nova. Proc. Natl Acad. Sci. USA 87, 1481-1485 (1990).
-
(1990)
Proc. Natl Acad. Sci. USA
, vol.87
, pp. 1481-1485
-
-
Hicke, B.J.1
Celander, D.W.2
MacDonald, G.H.3
Price, C.M.4
Cech, T.R.5
-
23
-
-
0032431057
-
Crystal structure of the Oxytricha nova telomere end binding protein complexed with single strand DNA
-
Horvath, M. P., Schweiker, V. L., Bevilacqua, J. M., Ruggles, J. A. & Schultz, S. C. Crystal structure of the Oxytricha nova telomere end binding protein complexed with single strand DNA. Cell 95, 963-974 (1998).
-
(1998)
Cell
, vol.95
, pp. 963-974
-
-
Horvath, M.P.1
Schweiker, V.L.2
Bevilacqua, J.M.3
Ruggles, J.A.4
Schultz, S.C.5
-
24
-
-
0025984268
-
Cloning and expression of genes for the Oxytricha telomere-binding protein: Specific subunit interactions in the telomeric complex
-
Gray, J. T., Celander, D. W., Price, C. M. & Cech, T. R. Cloning and expression of genes for the Oxytricha telomere-binding protein: specific subunit interactions in the telomeric complex. Cell 67, 807-814 (1991).
-
(1991)
Cell
, vol.67
, pp. 807-814
-
-
Gray, J.T.1
Celander, D.W.2
Price, C.M.3
Cech, T.R.4
-
25
-
-
1842529179
-
DNA binding features of human POT1: A nonamer 5′-TAGGGTTAG-3′ minimal binding site, sequence specificity, and internal binding to multimeric sites
-
Loayza, D., Parsons, H., Donigian, J., Hoke, K. & de Lange, T. DNA binding features of human POT1: a nonamer 5′-TAGGGTTAG-3′ minimal binding site, sequence specificity, and internal binding to multimeric sites. J. Biol. Chem. 279, 13241-13248 (2004).
-
(2004)
J. Biol. Chem
, vol.279
, pp. 13241-13248
-
-
Loayza, D.1
Parsons, H.2
Donigian, J.3
Hoke, K.4
de Lange, T.5
-
26
-
-
20144382152
-
Switching human telomerase on and off with hPOT1 protein in vitro
-
Lei, M., Zaug, A. J., Podell, E. R. & Cech, T. R. Switching human telomerase on and off with hPOT1 protein in vitro. J. Biol. Chem. 280, 20449-20456 (2005).
-
(2005)
J. Biol. Chem
, vol.280
, pp. 20449-20456
-
-
Lei, M.1
Zaug, A.J.2
Podell, E.R.3
Cech, T.R.4
-
27
-
-
0026091685
-
Molecular cloning of telomere-binding protein genes from Stylonychia mytilis
-
Fang, G. W. & Cech, T. R. Molecular cloning of telomere-binding protein genes from Stylonychia mytilis. Nucleic Acids Res. 19, 5515-5518 (1991).
-
(1991)
Nucleic Acids Res
, vol.19
, pp. 5515-5518
-
-
Fang, G.W.1
Cech, T.R.2
-
28
-
-
0027168268
-
Oxytricha telomere-binding protein: Separable DNA-binding and dimerization domains of the α-subunit
-
Fang, G., Gray, J. T. & Cech, T. R. Oxytricha telomere-binding protein: separable DNA-binding and dimerization domains of the α-subunit. Genes Dev. 7, 870-882 (1993).
-
(1993)
Genes Dev
, vol.7
, pp. 870-882
-
-
Fang, G.1
Gray, J.T.2
Cech, T.R.3
-
29
-
-
0027220845
-
The b subunit of Oxytricha telomere-binding protein promotes G-quartet formation by telomeric DNA
-
Fang, G. & Cech, T. R. The b subunit of Oxytricha telomere-binding protein promotes G-quartet formation by telomeric DNA. Cell 74, 875-885 (1993).
-
(1993)
Cell
, vol.74
, pp. 875-885
-
-
Fang, G.1
Cech, T.R.2
-
30
-
-
27144451010
-
Telomere endbinding proteins control the formation of G-quadruplex DNA structures in vivo
-
Paeschke, K., Simonsson, T., Postberg, J., Rhodes, D. & Lipps, H. J. Telomere endbinding proteins control the formation of G-quadruplex DNA structures in vivo. Nature Struct. Mol. Biol. 12, 847-854 (2005).
-
(2005)
Nature Struct. Mol. Biol
, vol.12
, pp. 847-854
-
-
Paeschke, K.1
Simonsson, T.2
Postberg, J.3
Rhodes, D.4
Lipps, H.J.5
-
31
-
-
0034753838
-
Identification of homology in protein structure classification
-
Dietmann, S. & Holm, L. Identification of homology in protein structure classification. Nature Struct. Biol. 8, 953-957 (2001).
-
(2001)
Nature Struct. Biol
, vol.8
, pp. 953-957
-
-
Dietmann, S.1
Holm, L.2
-
32
-
-
0012767432
-
Nucleic acid recognition by OBfold proteins
-
Theobald, D. L., Mitton-Fry, R. M. & Wuttke, D. S. Nucleic acid recognition by OBfold proteins. Annu. Rev. Biophys. Biomol. Struct. 32, 115-133 (2003).
-
(2003)
Annu. Rev. Biophys. Biomol. Struct
, vol.32
, pp. 115-133
-
-
Theobald, D.L.1
Mitton-Fry, R.M.2
Wuttke, D.S.3
-
33
-
-
0025978283
-
Database algorithm for generating protein backbone and side-chain co-ordinates from a Ca trace application to model building and detection of co-ordinate errors
-
Holm, L. & Sander, C. Database algorithm for generating protein backbone and side-chain co-ordinates from a Ca trace application to model building and detection of co-ordinate errors. J. Mol. Biol. 218, 183-194 (1991).
-
(1991)
J. Mol. Biol
, vol.218
, pp. 183-194
-
-
Holm, L.1
Sander, C.2
-
34
-
-
0037439107
-
Determinants in mammalian telomerase RNA that mediate enzyme processivity and cross-species incompatibility
-
Chen, J. L. & Greider, C. W. Determinants in mammalian telomerase RNA that mediate enzyme processivity and cross-species incompatibility. EMBO J. 22, 304-314 (2003).
-
(2003)
EMBO J
, vol.22
, pp. 304-314
-
-
Chen, J.L.1
Greider, C.W.2
-
35
-
-
23344451160
-
Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro
-
Zaug, A. J., Podell, E. R. & Cech, T. R. Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro. Proc. Natl Acad. Sci. USA 102, 10864-10869 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 10864-10869
-
-
Zaug, A.J.1
Podell, E.R.2
Cech, T.R.3
-
36
-
-
0027772958
-
Sliding clamps of DNA polymerases
-
Kuriyan, J. & O'Donnell, M. Sliding clamps of DNA polymerases. J. Mol. Biol. 234, 915-925 (1993).
-
(1993)
J. Mol. Biol
, vol.234
, pp. 915-925
-
-
Kuriyan, J.1
O'Donnell, M.2
-
37
-
-
0026523228
-
Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
-
Counter, C. M. et al. Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J. 11, 1921-1929 (1992).
-
(1992)
EMBO J
, vol.11
, pp. 1921-1929
-
-
Counter, C.M.1
-
38
-
-
2042534735
-
Telomere length homeostasis is achieved via a switch between telomerase-extendible and -nonextendible states
-
Teixeira, M. T., Arneric, M., Sperisen, P. & Lingner, J. Telomere length homeostasis is achieved via a switch between telomerase-extendible and -nonextendible states. Cell 117, 323-335 (2004).
-
(2004)
Cell
, vol.117
, pp. 323-335
-
-
Teixeira, M.T.1
Arneric, M.2
Sperisen, P.3
Lingner, J.4
|