Regulation of telomere length by checkpoint genes in Schizosaccharomyces pombe

Molecular Biology of the Cell

Volumn 9, Issue 3, 1998, Pages 611-621

  Dahlén, Maria ^a   Olsson, Tim ^a   Kanter Smoler, Gunilla ^a   Ramne, Anna ^a   Sunnerhagen, Per ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; HYDROXYUREA; NUCLEOTIDE; PROTEIN KINASE;

ARTICLE; CELL CYCLE; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; GENE; GENE EXPRESSION; MUTATION; NONHUMAN; PRIORITY JOURNAL; SCHIZOSACCHAROMYCES POMBE; TELOMERE;

SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES POMBE;

EID: 0031916104     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.9.3.611     Document Type: Article

References (60)

1. Al-Khodairy, F., and Carr, A.M. (1992). DNA repair mutants defining G2 checkpoint pathways in Schizosaccharomyces pombe. EMBO J. 11, 1343-1350.
2. Al-Khodairy, F., Fotou, E., Sheldrick, K.S., Griffiths, D.J.F., Lehmann, A.R., and Carr, A.M. (1994). Identification and characterization of new elements involved in checkpoint and feedback controls in fission yeast. Mol. Biol. Cell 5, 147-160.
3. Allshire, R., Nimmo, E.R., Ekwall, K., Javerzat, J.P., and Cranston, G. (1995). Mutations derepressing silent centromeric domains in fission yeast disrupt chromosome segregation. Genes Dev. 9, 218-233.
4. Birkenbihl, R.P., and Subramani, S. (1992). Cloning and characterization of rad21, an essential gene of Schizosaccharomyces pombe involved in DNA double-strand-break repair. Nucleic Acids Res. 20, 6605-6611.
5. Boulton, S.J., and Jackson, S.P. (1996). Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance. Nucleic Acids Res. 24, 4639-4648.
6. Carr, A.M., and Hoekstra, M.F. (1995). The cellular responses to DNA damage. Trends Cell Biol. 5, 32-40.
7. Carr, A.M., Schmidt, H., Kirchhoff, S., Muriel, W.J., Sheldrick, K.S., Griffiths, D.J., Basmacioglu, C.N., Subramani, S., Clegg, M., Nasim, A., and Lehmann, A.R. (1994). The radio gene of Schizosaccharomyces pombe: a homolog of the RAD1 gene of Saccharomyces cerevisiae. Mol. Cell. Biol. 14, 2029-2040.
8. Cooper, J.P., Nimmo, E.R., Allshire, R.C., and Cech, T.R. (1997). Regulation of telomere length and function by a Myb-domain protein in fission yeast. Nature 355, 744-747.
9. Dahlkvist, A., Kanter-Smoler, G., and Sunnerhagen, P. (1995). The RCK1 and RCK2 protein kinase genes from Saccharomyces cerevisiae suppress cell cycle checkpoint mutations in Schizosaccharomyces pombe. Mol. Gen. Genet. 246, 316-326.
10. Dahlkvist, A., and Sunnerhagen, P. (1994). Two novel deduced serine/threonine protein kinases from Saccharomyces cerevisiae. Gene 139, 27-33.
11. Doe, C.L., Murray, J.M., Shayeghi, M., Hoskins, M., Lehmann, A.R., Carr, A.M., and Watts, F.Z. (1993). Cloning and characterisation of the Schizosacctiaromyces pombe rad8 gene, a member of the Snf2 helicase family. Nucleic Acids Res. 22, 5964-5971.
12. Duffy, M., and Chambers, A. (1996). DNA-protein interactions at the telomeric repeats of Schizosaccharomyces pombe. Nucleic Acids Res. 24, 1412-1419.
13. Durso, G., Grallert, B., and Nurse, P. (1995). DNA polymerase α, a component of the replication initiation complex, is essential for the checkpoint coupling S phase to mitosis in fission yeast. J. Cell Sci. 108, 3109-3118.
14. Enoch, T., Carr, A.M., and Nurse, P. (1992). Fission yeast genes involved in coupling mitosis to completion of DNA replication. Genes Dev. 6, 2035-2046.
15. Feinberg, A.P., and Vogelstein, B. (1983). A technique for labeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 232, 6-13.
16. Francesconi, S., De Recondo, A.M., and Baldacci, G. (1995). DNA polymerase Δ is required for the replication feedback control of cell cycle progression in Schizosaccharomyces pombe. Mol. Gen. Genet. 246, 561-569.
17. Funabiki, H., Hagan, I., Uzawa, S., and Yanagida, M. (1993). Cell cycle-dependent specific positioning and clustering of centromeres and telomeres in fission yeast. J. Cell Biol. 222, 961-976.
18. Furnari, B., Rhind, N., and Russell, P. (1997). Cdc25 mitotic inducer targeted by Chk1 DNA damage checkpoint kinase. Science 277, 1495-1497.
19. Garvik, B., Carson, M., and Hartwell, L. (1995). Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint. Mol. Cell. Biol. 25, 6128-6138.
20. Greenwell, P.W., Kronmal, S.L., Porter, S.E., Gassenhuber, J., Obermaier, B., and Petes, T.D. (1995). TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene. Cell 82, 823-829.
21. Griffiths, D.J.F., Barbet, N.C., McCready, S., Lehmann, A.R., and Carr, A.M. (1995). Fission yeast rad17: a homologue of budding yeast RAD24 that shares regions of sequence similarity with DNA polymerase accessory proteins. EMBO J. 14, 5812-5823.
22. Grimm, C., Kohli, J., Murray, J., and Maundrell, K. (1988). Genetic engineering of Schizosaccharomyces pombe: a system for gene disruption and replacement using the ura4 gene as a selectable marker. Mol. Gen. Genet. 225, 81-86.
23. Gutz, H., Heslot, H., Leupold, U., and Loprieno, N. (1974). Schizosaccharomyces pombe. In: Bacteria, Bacteriophages, and Fungi, ed. R.C. King, New York, Plenum, 395-446.
24. Hoffman, C.S., and Winston, F. (1987). A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli. Gene 57, 267-272.
25. Kanter-Smoler, G., Dahlkvist, A., and Sunnerhagen, P. (1994). Improved method for rapid transformation of intact Schizosaccharomyces pombe cells. Biotechniques 26, 798-800.
26. +. Mol. Biol. Cell 6, 1793-1805.
27. Lehmann, A.R. (1996). Molecular biology of DNA repair in the fission yeast Schizosaccharomyces pombe. Mutat. Res. 363, 147-161.
28. Li, B., and Lustig, A.J. (1996). A novel mechanism for telomere size control in Saccharomyces cerevisiae. Genes Dev. 20, 1310-1326.
29. Lin, J.J., and Zakian, V.A. (1995). An in vitro assay for Saccharomyces telomerase requires EST1. Cell 81, 1127-1135.
30. Long, K.E., Sunnerhagen, P., and Subramani, S. (1994). The Schizosaccharomyces pombe rad1 gene consists of three exons and the cDNA sequence is partially homologous to the Ustilago maydis REC1 cDNA. Gene 148, 155-159.
31. Lustig, A.J., and Petes, T.D. (1986). Identification of yeast mutants with altered telomere structure. Proc. Natl. Acad. Sci. USA 83, 1398-1402.
32. Lydall, D., and Weinert, T. (1995). Yeast checkpoint genes in DNA damage processing: implications for repair and arrest. Science 270, 1488-1491.
33. Metcalfe, J.A., Parkhill, J., Campbell, L., Stacey, M., Biggs, P., Byrd, P.J., and Taylor, M.R. (1996). Accelerated telomere shortening in ataxia telangiectasia. Nat. Genet. 13, 350-353.
34. Moreno, S., Klar, A., and Nurse, P. (1991). Molecular generic analysis of the fission yeast Schizosaccharomyces pombe. Methods Enzymol. 194, 795-823.
35. Morrow, D.M., Morrow, M., Tagle, D.A., Shiloh, Y., Collins, F.S., and Hieter, P. (1995). TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1. Cell 82, 831-840.
36. Murakami, H., and Okayama, H. (1995). A kinase from fission yeast responsible for blocking mitosis in S phase. Nature 374, 817-819.
37. Murray, J.M., Carr, A.M., Lehmann, A.R., and Watts, F.Z. (1991). Cloning and characterization of the rad9 DNA repair gene from Schizosaccharomyces pombe. Nucleic Acids Res. 79, 3525-3531.
38. Murray, J.M., Tavassoli, M., Al-Harithy, R., Sheldrick, K.S., Lehmann, A.R., Carr, A.M., and Watts, F.Z. (1994). Structural and functional conservation of the human homolog of the Schizosaccharomyces pombe rad2 gene, which is required for chromosome segregation and recovery from DNA damage. Mol. Cell. Biol. 14, 4878-4888.
39. Nakamura, T.M., Morin, G.B., Chapman, K.B., Weinrich, S.L., Andrews, W.H., Lingner, J., Harley, C.B., and Cech, T.R. (1997). Telomerase catalytic subunit homologs from fission yeast and human. Science 277, 955-959.
40. Navas, T.A., Zhou, Z., and Elledge, S.J. (1995). DNA polymerase, links the DNA replication machinery to the S phase checkpoint. Cell 80, 29-39.
41. Nimmo, E.R., Cranston, G., and Allshire, R.C. (1994). Telomere-associated chromosome breakage in fission yeast results in variegated expression of adjacent genes. EMBO J. 23, 3801-3811.
42. Niwa, O., Matsumoto, Y., Chikasage, Y., and Yanagida, M. (1989). Characterization of Schizosaccharomyces pombe minichromosome deletion derivatives and a functional allocation of their centromere. EMBO J. 8, 3045-3052.
43. Nugent, C.I., Hughes, T.R., Lue, N.F., and Lundblad, V. (1996). Cdcl3p: a single-strand telomeric DNA-binding protein with a dual role in yeast telomere maintenance. Science 274, 249-252.
44. Paulovich, A.G., and Hartwell, L.H. (1995). A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage. Cell 82, 841-847.
45. Porter, S.E., Greenwell, P.W., Ritchie, K.B., and Petes, T.D. (1996). The DNA-binding protein Hdf1p (a putative Ku homologue) is required for maintaining normal telomere length in Saccharomyces cerevisiae. Nucleic Acids Res. 24, 582-585.
46. Runge, K.W., and Zakian, V.A. (1996). TEL2, an essential gene required for telomere length regulation and telomere position effect in Saccharomyces cerevisiae. Mol. Cell. Biol. 16, 3094-3105.
47. 4 functions as an inducer in the mitotic control of fission yeast. Cell 45, 145-153.
48. +, a gene encoding a protein kinase homolog. Cell 49, 559-567.
49. Sandell, L.L., and Zakian, V.A. (1993). Loss of a yeast telomere: arrest, recovery, and chromosome loss. Cell 75, 729-739.
50. Savitsky, K., et al. (1995). A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science 268, 1749-1753.
51. Siede, W., Nusspaumer, G., Portillo, V., Rodriguez, R., and Friedberg, E.C. (1996). Cloning and characterization of RAD17, a gene controlling cell cycle responses to DNA damage in Saccharoimjces cerevisiae. Nucleic Acids Res. 24, 1669-1675.
52. Sugawara, N. (1989). DNA sequences at the telomeres of the fission yeast S. pombe. Ph.D. Thesis, Cambridge, MA: Harvard University.
53. Sunnerhagen, P. (1993). PCR used to determine mating type in Schizosaccharomyces pombe. Biotechniques 24, 18.
54. Sunnerhagen, P., Seaton, B.L., Nasim, A., and Subramani, S. (1990). Cloning and analysis of a gene involved in DNA repair and recombination, the rad1 gene of Schizosaccharomyces pombe. Mol. Cell. Biol. 20, 3750-3760.
55. Thelen, M.P., Onel, K., and Holloman, W.K. (1994). The REC1 gene of Ustilago maydis involved in the cellular response to DNA damage encodes an exonuclease. J. Biol. Chem. 269, 747-754.
56. Tsukamoto, Y., Kato, J., and Ikeda, H. (1997). Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae. Nature 388, 900-903.
57. Walworth, N., Davey, S., and Beach, D. (1993). Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2. Nature 363, 368-371.
58. Weinert, T.A., and Hartwell, L.H. (1993). Cell cycle arrest of cdc mutants and specificity of the RAD9 checkpoint. Genetics 134, 63-80.
59. Weinert, T.A., Kiser, G.L., and Hartwell, L.H. (1994). Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair. Genes Dev. 8, 652-665.
60. Zakian, V.A. (1995). Saccharomyces telomeres: function, structure and replication. In: Telomeres. eds. E.H. Blackburn and C.W. Greider. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 107-137.