Cdc13 delivers separate complexes to the telomere for end protection and replication

Cell

Volumn 104, Issue 3, 2001, Pages 387-396

  Pennock, Erin ^a   Buckley, Kathleen ^a   Lundblad, Victoria ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; PROTEIN CDC13; TELOMERASE; UNCLASSIFIED DRUG;

ARTICLE; DNA BINDING; DNA REPLICATION; DNA STRUCTURE; ENZYME ACTIVITY; GENE EXPRESSION; GENE MUTATION; GENE TARGETING; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; TELOMERE;

SACCHAROMYCES CEREVISIAE;

EID: 0035830494     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(01)00226-4     Document Type: Article

References (34)

1. Specific DNA replication mutations affect telomere length in Saccharomyces cerevisiae
2. Extension of life-span by introduction of telomerase into normal human cells
3. CDC17: An essential gene that prevents telomere elongation in yeast
4. Cdc13 both positively and negatively regulates telomere replication
5. The catalytic subunit of yeast telomerase
6. Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases α and δ
7. Est1 and Cdc13 as comediators of telomerase access
8. Positive and negative regulation of telomerase access to the telomere
9. The RNA component of human telomerase
10. Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint
11. Cdc13 cooperates with the yeast Ku proteins and Stn1 to regulate telomerase recruitment
12. Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13
13. A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis
14. Mammalian telomeres end in a large duplex loop
15. The Est3 protein is a subunit of yeast telomerase
16. Identification of the single strand DNA binding domain of the Saccharomyces cerevisiae Cdc13 protein
17. p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2
18. Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes
19. Reverse transcriptase motifs in the catalytic subunit of telomerase
20. Three Ever Shorter Telomere (EST) genes are dispensable for in vitro yeast telomerase activity
21. DNA ends: Maintenance of chromosome termini versus repair of double strand breaks
22. - senescence
23. A mutant with a defect in telomere elongation leads to senescence in yeast
24. Telomere fusions caused by mutating the terminal region of telomeric DNA
25. Programmed translational frameshifting in a gene required for yeast telomere replication
26. Two modes of survival of fission yeast without telomerase
27. Cdc13p: A single-strand telomeric DNA-binding protein with a dual role in yeast telomere maintenance
28. The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase α and the telomerase-associated Est1 protein
29. Allele-specific suppression by formation of new protein-protein interactions in yeast
30. TLC1: Template Rna component of Saccharomyces cerevisiae telomerase
31. TRF2 protects human telomeres from end-to-end fusions
32. Cell cycle arrest of cdc mutants and specificity of the RAD9 checkpoint
33. 1-3 tails late in S phase
34. Evidence for a new step in telomere maintenance