-
1
-
-
33747704196
-
Microarrays and the microscope: balancing throughput with resolution
-
Coppola, G. and Geschwind, D.H. (2006) Microarrays and the microscope: balancing throughput with resolution. J. Physiol., 575, 353-359.
-
(2006)
J. Physiol.
, vol.575
, pp. 353-359
-
-
Coppola, G.1
Geschwind, D.H.2
-
2
-
-
67249133451
-
Functional genomic analysis of frataxin deficiency reveals tissue-specific alterations and identifies the PPARgamma pathway as a therapeutic target in Friedreich's ataxia
-
Coppola, G., Marmolino, D., Lu, D., Wang, Q., Cnop, M., Rai, M., Acquaviva, F., Cocozza, S., Pandolfo, M. and Geschwind, D.H. (2009) Functional genomic analysis of frataxin deficiency reveals tissue-specific alterations and identifies the PPARgamma pathway as a therapeutic target in Friedreich's ataxia. Hum. Mol. Genet., 18, 2452-2461.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 2452-2461
-
-
Coppola, G.1
Marmolino, D.2
Lu, D.3
Wang, Q.4
Cnop, M.5
Rai, M.6
Acquaviva, F.7
Cocozza, S.8
Pandolfo, M.9
Geschwind, D.H.10
-
3
-
-
33748174617
-
A genomic screen for modifiers of tauopathy identifies puromycin-sensitive aminopeptidase as an inhibitor of tau-induced neurodegeneration
-
Karsten, S.L., Sang, T.K., Gehman, L.T., Chatterjee, S., Liu, J., Lawless, G.M., Sengupta, S., Berry, R.W., Pomakian, J., Oh, H.S. et al. (2006) A genomic screen for modifiers of tauopathy identifies puromycin-sensitive aminopeptidase as an inhibitor of tau-induced neurodegeneration. Neuron, 51, 549-560.
-
(2006)
Neuron
, vol.51
, pp. 549-560
-
-
Karsten, S.L.1
Sang, T.K.2
Gehman, L.T.3
Chatterjee, S.4
Liu, J.5
Lawless, G.M.6
Sengupta, S.7
Berry, R.W.8
Pomakian, J.9
Oh, H.S.10
-
4
-
-
20044377403
-
Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice
-
Lazarov, O., Robinson, J., Tang, Y.P., Hairston, I.S., Korade-Mirnics, Z., Lee, V.M., Hersh, L.B., Sapolsky, R.M., Mirnics, K. and Sisodia, S.S. (2005) Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice. Cell, 120, 701-713.
-
(2005)
Cell
, vol.120
, pp. 701-713
-
-
Lazarov, O.1
Robinson, J.2
Tang, Y.P.3
Hairston, I.S.4
Korade-Mirnics, Z.5
Lee, V.M.6
Hersh, L.B.7
Sapolsky, R.M.8
Mirnics, K.9
Sisodia, S.S.10
-
5
-
-
33344470365
-
FACS-array profiling of striatal projection neuron subtypes in juvenile and adult mouse brains
-
Lobo, M.K., Karsten, S.L., Gray, M., Geschwind, D.H. and Yang, X.W. (2006) FACS-array profiling of striatal projection neuron subtypes in juvenile and adult mouse brains. Nat. Neurosci., 9, 443-452.
-
(2006)
Nat. Neurosci.
, vol.9
, pp. 443-452
-
-
Lobo, M.K.1
Karsten, S.L.2
Gray, M.3
Geschwind, D.H.4
Yang, X.W.5
-
6
-
-
66249118697
-
Sanfilippo syndrome type B, a lysosomal storage disease, is also a tauopathy
-
Ohmi, K., Kudo, L.C., Ryazantsev, S., Zhao, H.Z., Karsten, S.L. and Neufeld, E.F. (2009) Sanfilippo syndrome type B, a lysosomal storage disease, is also a tauopathy. Proc. Natl Acad. Sci. USA, 106, 8332-8337.
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 8332-8337
-
-
Ohmi, K.1
Kudo, L.C.2
Ryazantsev, S.3
Zhao, H.Z.4
Karsten, S.L.5
Neufeld, E.F.6
-
7
-
-
0042011475
-
DNA microarrays: translation of the genome from laboratory to clinic
-
Geschwind, D.H. (2003) DNA microarrays: translation of the genome from laboratory to clinic. Lancet Neurol., 2, 275-282.
-
(2003)
Lancet Neurol.
, vol.2
, pp. 275-282
-
-
Geschwind, D.H.1
-
8
-
-
3943102116
-
Unraveling the mechanisms involved in motor neuron degeneration in ALS
-
Bruijn, L.I., Miller, T.M. and Cleveland, D.W. (2004) Unraveling the mechanisms involved in motor neuron degeneration in ALS. Annu. Rev. Neurosci., 27, 723-749.
-
(2004)
Annu. Rev. Neurosci.
, vol.27
, pp. 723-749
-
-
Bruijn, L.I.1
Miller, T.M.2
Cleveland, D.W.3
-
9
-
-
0035240305
-
Progress in the pathogenesis of amyotrophic lateral sclerosis
-
Shaw, C.E., al-Chalabi, A. and Leigh, N. (2001) Progress in the pathogenesis of amyotrophic lateral sclerosis. Curr. Neurol. Neurosci. Rep., 1, 69-76.
-
(2001)
Curr. Neurol. Neurosci. Rep.
, vol.1
, pp. 69-76
-
-
Shaw, C.E.1
al-Chalabi, A.2
Leigh, N.3
-
10
-
-
0032482976
-
Absence of neurofilaments reduces the selective vulnerability of motor neurons and slows disease caused by a familial amyotrophic lateral sclerosis-linked superoxide dismutase 1 mutant
-
Williamson, T.L., Bruijn, L.I., Zhu, Q., Anderson, K.L., Anderson, S.D., Julien, J.P. and Cleveland, D.W. (1998) Absence of neurofilaments reduces the selective vulnerability of motor neurons and slows disease caused by a familial amyotrophic lateral sclerosis-linked superoxide dismutase 1 mutant. Proc. Natl Acad. Sci. USA, 95, 9631-9636.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 9631-9636
-
-
Williamson, T.L.1
Bruijn, L.I.2
Zhu, Q.3
Anderson, K.L.4
Anderson, S.D.5
Julien, J.P.6
Cleveland, D.W.7
-
11
-
-
3142514201
-
Protein aggregation and neurodegenerative disease
-
Ross, C.A. and Poirier, M.A. (2004) Protein aggregation and neurodegenerative disease. Nat. Med., 10 (suppl.), S10-S17.
-
(2004)
Nat. Med.
, vol.10
, Issue.SUPPL
-
-
Ross, C.A.1
Poirier, M.A.2
-
12
-
-
33846678063
-
How do ALS-associated mutations in superoxide dismutase 1 promote aggregation of the protein?
-
Shaw, B.F. and Valentine, J.S. (2007) How do ALS-associated mutations in superoxide dismutase 1 promote aggregation of the protein? Trends Biochem. Sci., 32, 78-85.
-
(2007)
Trends Biochem. Sci.
, vol.32
, pp. 78-85
-
-
Shaw, B.F.1
Valentine, J.S.2
-
13
-
-
0035676020
-
Progress in clinical neurosciences: the evidence for ALS as a multisystems disorder of limited phenotypic expression
-
Strong, M.J. (2001) Progress in clinical neurosciences: the evidence for ALS as a multisystems disorder of limited phenotypic expression. Can. J. Neurol. Sci., 28, 283-298.
-
(2001)
Can. J. Neurol. Sci.
, vol.28
, pp. 283-298
-
-
Strong, M.J.1
-
14
-
-
0029435316
-
Excitotoxicity and neurodegeneration in amyotrophic lateral sclerosis
-
Rothstein, J.D. (1995) Excitotoxicity and neurodegeneration in amyotrophic lateral sclerosis. Clin. Neurosci., 3, 348-359.
-
(1995)
Clin. Neurosci.
, vol.3
, pp. 348-359
-
-
Rothstein, J.D.1
-
15
-
-
0029441620
-
Excitotoxic mechanisms in the pathogenesis of amyotrophic lateral sclerosis
-
Discussion 21-27
-
Rothstein, J.D. (1995) Excitotoxic mechanisms in the pathogenesis of amyotrophic lateral sclerosis. Adv. Neurol., 68, 7-20. Discussion 21-27.
-
(1995)
Adv. Neurol.
, vol.68
, pp. 7-20
-
-
Rothstein, J.D.1
-
16
-
-
0029671220
-
Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis
-
Wiedau-Pazos, M., Goto, J.J., Rabizadeh, S., Gralla, E.B., Roe, J.A., Lee, M.K., Valentine, J.S. and Bredesen, D.E. (1996) Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis. Science, 271, 515-518.
-
(1996)
Science
, vol.271
, pp. 515-518
-
-
Wiedau-Pazos, M.1
Goto, J.J.2
Rabizadeh, S.3
Gralla, E.B.4
Roe, J.A.5
Lee, M.K.6
Valentine, J.S.7
Bredesen, D.E.8
-
17
-
-
0036321382
-
Mitochondrial DNA and respiratory chain function in spinal cords of ALS patients
-
Wiedemann, F.R., Manfredi, G., Mawrin, C., Beal, M.F. and Schon, E.A. (2002) Mitochondrial DNA and respiratory chain function in spinal cords of ALS patients. J. Neurochem., 80, 616-625.
-
(2002)
J. Neurochem.
, vol.80
, pp. 616-625
-
-
Wiedemann, F.R.1
Manfredi, G.2
Mawrin, C.3
Beal, M.F.4
Schon, E.A.5
-
18
-
-
33644817756
-
Mitochondrial dysfunction as a cause of axonal degeneration in multiple sclerosis patients
-
Dutta, R., McDonough, J., Yin, X., Peterson, J., Chang, A., Torres, T., Gudz, T., Macklin, W.B., Lewis, D.A., Fox, R.J. et al. (2006) Mitochondrial dysfunction as a cause of axonal degeneration in multiple sclerosis patients. Ann. Neurol., 59, 478-489.
-
(2006)
Ann. Neurol.
, vol.59
, pp. 478-489
-
-
Dutta, R.1
McDonough, J.2
Yin, X.3
Peterson, J.4
Chang, A.5
Torres, T.6
Gudz, T.7
Macklin, W.B.8
Lewis, D.A.9
Fox, R.J.10
-
19
-
-
0035437866
-
Recruitment of the mitochondrial-dependent apoptotic pathway in amyotrophic lateral sclerosis
-
Guegan, C., Vila, M., Rosoklija, G., Hays, A.P. and Przedborski, S. (2001) Recruitment of the mitochondrial-dependent apoptotic pathway in amyotrophic lateral sclerosis. J. Neurosci., 21, 6569-6576.
-
(2001)
J. Neurosci.
, vol.21
, pp. 6569-6576
-
-
Guegan, C.1
Vila, M.2
Rosoklija, G.3
Hays, A.P.4
Przedborski, S.5
-
20
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
Rosen, D.R., Siddique, T., Patterson, D., Figlewicz, D.A., Sapp, P., Hentati, A., Donaldson, D., Goto, J., O'Regan, J.P., Deng, H.X. et al. (1993) Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature, 362, 59-62.
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
Figlewicz, D.A.4
Sapp, P.5
Hentati, A.6
Donaldson, D.7
Goto, J.8
O'Regan, J.P.9
Deng, H.X.10
-
21
-
-
79961149073
-
Current status of SOD1 mutations in familial amyotrophic lateral sclerosis
-
Gaudette, M., Hirano, M. and Siddique, T. (2000) Current status of SOD1 mutations in familial amyotrophic lateral sclerosis. Amyotroph. Lateral Scler, 1, 83-89.
-
(2000)
Amyotroph. Lateral Scler
, vol.1
, pp. 83-89
-
-
Gaudette, M.1
Hirano, M.2
Siddique, T.3
-
22
-
-
0039251419
-
Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase
-
Estevez, A.G., Crow, J.P., Sampson, J.B., Reiter, C., Zhuang, Y., Richardson, G.J., Tarpey, M.M., Barbeito, L. and Beckman, J.S. (1999) Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase. Science, 286, 2498-2500.
-
(1999)
Science
, vol.286
, pp. 2498-2500
-
-
Estevez, A.G.1
Crow, J.P.2
Sampson, J.B.3
Reiter, C.4
Zhuang, Y.5
Richardson, G.J.6
Tarpey, M.M.7
Barbeito, L.8
Beckman, J.S.9
-
23
-
-
1942437507
-
Mechanisms for activating Cu-and Zn-containing superoxide dismutase in the absence of the CCS Cu chaperone
-
Carroll, M.C., Girouard, J.B., Ulloa, J.L., Subramaniam, J.R., Wong, P.C., Valentine, J.S. and Culotta, V.C. (2004) Mechanisms for activating Cu-and Zn-containing superoxide dismutase in the absence of the CCS Cu chaperone. Proc. Natl Acad. Sci. USA, 101, 5964-5969.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 5964-5969
-
-
Carroll, M.C.1
Girouard, J.B.2
Ulloa, J.L.3
Subramaniam, J.R.4
Wong, P.C.5
Valentine, J.S.6
Culotta, V.C.7
-
24
-
-
0032544674
-
Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1
-
Bruijn, L.I., Houseweart, M.K., Kato, S., Anderson, K.L., Anderson, S.D., Ohama, E., Reaume, A.G., Scott, R.W. and Cleveland, D.W. (1998) Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1. Science, 281, 1851-1854.
-
(1998)
Science
, vol.281
, pp. 1851-1854
-
-
Bruijn, L.I.1
Houseweart, M.K.2
Kato, S.3
Anderson, K.L.4
Anderson, S.D.5
Ohama, E.6
Reaume, A.G.7
Scott, R.W.8
Cleveland, D.W.9
-
25
-
-
0019784990
-
Morphometric comparison of the vulnerability of peripheral motor and sensory neurons in amyotrophic lateral sclerosis
-
Kawamura, Y., Dyck, P.J., Shimono, M., Okazaki, H., Tateishi, J. and Doi, H. (1981) Morphometric comparison of the vulnerability of peripheral motor and sensory neurons in amyotrophic lateral sclerosis. J. Neuropathol. Exp. Neurol., 40, 667-675.
-
(1981)
J. Neuropathol. Exp. Neurol.
, vol.40
, pp. 667-675
-
-
Kawamura, Y.1
Dyck, P.J.2
Shimono, M.3
Okazaki, H.4
Tateishi, J.5
Doi, H.6
-
26
-
-
54049140363
-
The syndromes of frontotemporal dysfunction in amyotrophic lateral sclerosis
-
Strong, M.J. (2008) The syndromes of frontotemporal dysfunction in amyotrophic lateral sclerosis. Amyotroph. Lateral Scler., 9, 323-338.
-
(2008)
Amyotroph. Lateral Scler.
, vol.9
, pp. 323-338
-
-
Strong, M.J.1
-
27
-
-
61549122708
-
Genetic studies of amyotrophic lateral sclerosis: controversies and perspectives
-
Beleza-Meireles, A. and Al-Chalabi, A. (2009) Genetic studies of amyotrophic lateral sclerosis: controversies and perspectives. Amyotroph. Lateral Scler., 10, 1-14.
-
(2009)
Amyotroph. Lateral Scler.
, vol.10
, pp. 1-14
-
-
Beleza-Meireles, A.1
Al-Chalabi, A.2
-
28
-
-
64649086140
-
Recent advances in the genetics of amyotrophic lateral sclerosis
-
Valdmanis, P.N., Daoud, H., Dion, P.A. and Rouleau, G.A. (2009) Recent advances in the genetics of amyotrophic lateral sclerosis. Curr. Neurol. Neurosci. Rep., 9, 198-205.
-
(2009)
Curr. Neurol. Neurosci. Rep.
, vol.9
, pp. 198-205
-
-
Valdmanis, P.N.1
Daoud, H.2
Dion, P.A.3
Rouleau, G.A.4
-
29
-
-
37349063722
-
The neuropathology of FTD associated With ALS
-
Mackenzie, I.R. (2007) The neuropathology of FTD associated With ALS. Alzheimer Dis. Assoc. Disord., 21, S44-S49.
-
(2007)
Alzheimer Dis. Assoc. Disord.
, vol.21
-
-
Mackenzie, I.R.1
-
30
-
-
0346734159
-
Microtubule-associated tau protein positive neuronal and glial inclusions in ALS
-
Yang, W., Sopper, M.M., Leystra-Lantz, C. and Strong, M.J. (2003) Microtubule-associated tau protein positive neuronal and glial inclusions in ALS. Neurology, 61, 1766-1773.
-
(2003)
Neurology
, vol.61
, pp. 1766-1773
-
-
Yang, W.1
Sopper, M.M.2
Leystra-Lantz, C.3
Strong, M.J.4
-
31
-
-
33745654119
-
Tau protein hyperphosphorylation in sporadic ALS with cognitive impairment
-
Strong, M.J., Yang, W., Strong, W.L., Leystra-Lantz, C., Jaffe, H. and Pant, H.C. (2006) Tau protein hyperphosphorylation in sporadic ALS with cognitive impairment. Neurology, 66, 1770-1771.
-
(2006)
Neurology
, vol.66
, pp. 1770-1771
-
-
Strong, M.J.1
Yang, W.2
Strong, W.L.3
Leystra-Lantz, C.4
Jaffe, H.5
Pant, H.C.6
-
32
-
-
39149141844
-
Upregulation of GSK3beta expression in frontal and temporal cortex in ALS with cognitive impairment (ALSci)
-
Yang, W., Leystra-Lantz, C. and Strong, M.J. (2008) Upregulation of GSK3beta expression in frontal and temporal cortex in ALS with cognitive impairment (ALSci). Brain Res., 1196, 131-139.
-
(2008)
Brain Res.
, vol.1196
, pp. 131-139
-
-
Yang, W.1
Leystra-Lantz, C.2
Strong, M.J.3
-
33
-
-
0038665270
-
Novel tau polymorphisms, tau haplotypes, and splicing in familial and sporadic frontotemporal dementia
-
Sobrido, M.J., Miller, B.L., Havlioglu, N., Zhukareva, V., Jiang, Z., Nasreddine, Z.S., Lee, V.M., Chow, T.W., Wilhelmsen, K.C., Cummings, J.L. et al. (2003) Novel tau polymorphisms, tau haplotypes, and splicing in familial and sporadic frontotemporal dementia. Arch. Neurol., 60, 698-702.
-
(2003)
Arch. Neurol.
, vol.60
, pp. 698-702
-
-
Sobrido, M.J.1
Miller, B.L.2
Havlioglu, N.3
Zhukareva, V.4
Jiang, Z.5
Nasreddine, Z.S.6
Lee, V.M.7
Chow, T.W.8
Wilhelmsen, K.C.9
Cummings, J.L.10
-
34
-
-
12144288280
-
17q-linked frontotemporal dementia-amyotrophic lateral sclerosis without tau mutations with tau and alpha-synuclein inclusions
-
Wilhelmsen, K.C., Forman, M.S., Rosen, H.J., Alving, L.I., Goldman, J., Feiger, J., Lee, J.V., Segall, S.K., Kramer, J.H., Lomen-Hoerth, C. et al. (2004) 17q-linked frontotemporal dementia-amyotrophic lateral sclerosis without tau mutations with tau and alpha-synuclein inclusions. Arch. Neurol., 61, 398-406.
-
(2004)
Arch. Neurol.
, vol.61
, pp. 398-406
-
-
Wilhelmsen, K.C.1
Forman, M.S.2
Rosen, H.J.3
Alving, L.I.4
Goldman, J.5
Feiger, J.6
Lee, J.V.7
Segall, S.K.8
Kramer, J.H.9
Lomen-Hoerth, C.10
-
35
-
-
33749668139
-
Amyotrophic lateral sclerosis with dementia: an autopsy case showing many Bunina bodies, tau-positive neuronal and astrocytic plaque-like pathologies, and pallido-nigral degeneration
-
Yokota, O., Tsuchiya, K., Oda, T., Ishihara, T., de Silva, R., Lees, A.J., Arai, T., Uchihara, T., Ishizu, H., Kuroda, S. et al. (2006) Amyotrophic lateral sclerosis with dementia: an autopsy case showing many Bunina bodies, tau-positive neuronal and astrocytic plaque-like pathologies, and pallido-nigral degeneration. Acta Neuropathol., 112, 633-645.
-
(2006)
Acta Neuropathol.
, vol.112
, pp. 633-645
-
-
Yokota, O.1
Tsuchiya, K.2
Oda, T.3
Ishihara, T.4
de Silva, R.5
Lees, A.J.6
Arai, T.7
Uchihara, T.8
Ishizu, H.9
Kuroda, S.10
-
36
-
-
34548157024
-
Microarray analysis of the cellular pathways involved in the adaptation to and progression of motor neuron injury in the SOD1 G93A mouse model of familial ALS
-
Ferraiuolo, L., Heath, P.R., Holden, H., Kasher, P., Kirby, J. and Shaw, P.J. (2007) Microarray analysis of the cellular pathways involved in the adaptation to and progression of motor neuron injury in the SOD1 G93A mouse model of familial ALS. J. Neurosci., 27, 9201-9219.
-
(2007)
J. Neurosci.
, vol.27
, pp. 9201-9219
-
-
Ferraiuolo, L.1
Heath, P.R.2
Holden, H.3
Kasher, P.4
Kirby, J.5
Shaw, P.J.6
-
37
-
-
34447294839
-
Gene expression analysis of the murine model of amyotrophic lateral sclerosis: studies of the Leu126delTT mutation in SOD1
-
Fukada, Y., Yasui, K., Kitayama, M., Doi, K., Nakano, T., Watanabe, Y. and Nakashima, K. (2007) Gene expression analysis of the murine model of amyotrophic lateral sclerosis: studies of the Leu126delTT mutation in SOD1. Brain Res., 1160, 1-10.
-
(2007)
Brain Res.
, vol.1160
, pp. 1-10
-
-
Fukada, Y.1
Yasui, K.2
Kitayama, M.3
Doi, K.4
Nakano, T.5
Watanabe, Y.6
Nakashima, K.7
-
38
-
-
0036062628
-
Temporal patterns of cytokine and apoptosis-related gene expression in spinal cords of the G93A-SOD1 mouse model of amyotrophic lateral sclerosis
-
Hensley, K., Floyd, R.A., Gordon, B., Mou, S., Pye, Q.N., Stewart, C., West, M. and Williamson, K. (2002) Temporal patterns of cytokine and apoptosis-related gene expression in spinal cords of the G93A-SOD1 mouse model of amyotrophic lateral sclerosis. J. Neurochem., 82, 365-374.
-
(2002)
J. Neurochem.
, vol.82
, pp. 365-374
-
-
Hensley, K.1
Floyd, R.A.2
Gordon, B.3
Mou, S.4
Pye, Q.N.5
Stewart, C.6
West, M.7
Williamson, K.8
-
39
-
-
34250656185
-
Toxicity from different SOD1 mutants dysregulates the complement system and the neuronal regenerative response in ALS motor neurons
-
Lobsiger, C.S., Boillee, S. and Cleveland, D.W. (2007) Toxicity from different SOD1 mutants dysregulates the complement system and the neuronal regenerative response in ALS motor neurons. Proc. Natl Acad. Sci. USA, 104, 7319-7326.
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 7319-7326
-
-
Lobsiger, C.S.1
Boillee, S.2
Cleveland, D.W.3
-
40
-
-
0035194691
-
Disease mechanisms revealed by transcription profiling in SOD1-G93A transgenic mouse spinal cord
-
Olsen, M.K., Roberds, S.L., Ellerbrock, B.R., Fleck, T.J., McKinley, D.K. and Gurney, M.E. (2001) Disease mechanisms revealed by transcription profiling in SOD1-G93A transgenic mouse spinal cord. Ann. Neurol., 50, 730-740.
-
(2001)
Ann. Neurol.
, vol.50
, pp. 730-740
-
-
Olsen, M.K.1
Roberds, S.L.2
Ellerbrock, B.R.3
Fleck, T.J.4
McKinley, D.K.5
Gurney, M.E.6
-
41
-
-
27744542191
-
No widespread induction of cell death genes occurs in pure motoneurons in an amyotrophic lateral sclerosis mouse model
-
Perrin, F.E., Boisset, G., Docquier, M., Schaad, O., Descombes, P. and Kato, A.C. (2005) No widespread induction of cell death genes occurs in pure motoneurons in an amyotrophic lateral sclerosis mouse model. Hum. Mol. Genet., 14, 3309-3320.
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 3309-3320
-
-
Perrin, F.E.1
Boisset, G.2
Docquier, M.3
Schaad, O.4
Descombes, P.5
Kato, A.C.6
-
42
-
-
0036269810
-
Differential expression of inflammation-and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis
-
Yoshihara, T., Ishigaki, S., Yamamoto, M., Liang, Y., Niwa, J., Takeuchi, H., Doyu, M. and Sobue, G. (2002) Differential expression of inflammation-and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis. J. Neurochem., 80, 158-167.
-
(2002)
J. Neurochem.
, vol.80
, pp. 158-167
-
-
Yoshihara, T.1
Ishigaki, S.2
Yamamoto, M.3
Liang, Y.4
Niwa, J.5
Takeuchi, H.6
Doyu, M.7
Sobue, G.8
-
43
-
-
59349090605
-
Transcriptional profile of primary astrocytes expressing ALS-linked mutant SOD1
-
Vargas, M.R., Pehar, M., Diaz-Amarilla, P.J., Beckman, J.S. and Barbeito, L. (2008) Transcriptional profile of primary astrocytes expressing ALS-linked mutant SOD1. J. Neurosci. Res., 86, 3515-3525.
-
(2008)
J. Neurosci. Res.
, vol.86
, pp. 3515-3525
-
-
Vargas, M.R.1
Pehar, M.2
Diaz-Amarilla, P.J.3
Beckman, J.S.4
Barbeito, L.5
-
44
-
-
1442282943
-
Molecular signature of late-stage human ALS revealed by expression profiling of postmortem spinal cord gray matter
-
Dangond, F., Hwang, D., Camelo, S., Pasinelli, P., Frosch, M.P., Stephanopoulos, G., Brown, R.H. Jr and Gullans, S.R. (2004) Molecular signature of late-stage human ALS revealed by expression profiling of postmortem spinal cord gray matter. Physiol. Genomics, 16, 229-239.
-
(2004)
Physiol. Genomics
, vol.16
, pp. 229-239
-
-
Dangond, F.1
Hwang, D.2
Camelo, S.3
Pasinelli, P.4
Frosch, M.P.5
Stephanopoulos, G.6
Brown R.H., Jr.7
Gullans, S.R.8
-
45
-
-
18744409323
-
Differentially expressed genes in sporadic amyotrophic lateral sclerosis spinal cords-screening by molecular indexing and subsequent cDNA microarray analysis
-
Ishigaki, S., Niwa, J., Ando, Y., Yoshihara, T., Sawada, K., Doyu, M., Yamamoto, M., Kato, K., Yotsumoto, Y. and Sobue, G. (2002) Differentially expressed genes in sporadic amyotrophic lateral sclerosis spinal cords-screening by molecular indexing and subsequent cDNA microarray analysis. FEBS Lett., 531, 354-358.
-
(2002)
FEBS Lett.
, vol.531
, pp. 354-358
-
-
Ishigaki, S.1
Niwa, J.2
Ando, Y.3
Yoshihara, T.4
Sawada, K.5
Doyu, M.6
Yamamoto, M.7
Kato, K.8
Yotsumoto, Y.9
Sobue, G.10
-
46
-
-
19944432585
-
Gene expression profile of spinal motor neurons in sporadic amyotrophic lateral sclerosis
-
Jiang, Y.M., Yamamoto, M., Kobayashi, Y., Yoshihara, T., Liang, Y., Terao, S., Takeuchi, H., Ishigaki, S., Katsuno, M., Adachi, H. et al. (2005) Gene expression profile of spinal motor neurons in sporadic amyotrophic lateral sclerosis. Ann. Neurol., 57, 236-251.
-
(2005)
Ann. Neurol.
, vol.57
, pp. 236-251
-
-
Jiang, Y.M.1
Yamamoto, M.2
Kobayashi, Y.3
Yoshihara, T.4
Liang, Y.5
Terao, S.6
Takeuchi, H.7
Ishigaki, S.8
Katsuno, M.9
Adachi, H.10
-
47
-
-
0035085455
-
Differential expression of 14 genes in amyotrophic lateral sclerosis spinal cord detected using gridded cDNA arrays
-
Malaspina, A., Kaushik, N. and de Belleroche, J. (2001) Differential expression of 14 genes in amyotrophic lateral sclerosis spinal cord detected using gridded cDNA arrays. J. Neurochem., 77, 132-145.
-
(2001)
J. Neurochem.
, vol.77
, pp. 132-145
-
-
Malaspina, A.1
Kaushik, N.2
de Belleroche, J.3
-
48
-
-
69249220446
-
Spinal cord mRNA profile in patients with ALS: comparison with transgenic mice expressing the human SOD-1 mutant
-
Offen, D., Barhum, Y., Melamed, E., Embacher, N., Schindler, C. and Ransmayr, G. (2009) Spinal cord mRNA profile in patients with ALS: comparison with transgenic mice expressing the human SOD-1 mutant. J. Mol. Neurosci., 38, 85-93.
-
(2009)
J. Mol. Neurosci.
, vol.38
, pp. 85-93
-
-
Offen, D.1
Barhum, Y.2
Melamed, E.3
Embacher, N.4
Schindler, C.5
Ransmayr, G.6
-
49
-
-
33847139464
-
Differential expression of genes in amyotrophic lateral sclerosis revealed by profiling the post mortem cortex
-
Wang, X.S., Simmons, Z., Liu, W., Boyer, P.J. and Connor, J.R. (2006) Differential expression of genes in amyotrophic lateral sclerosis revealed by profiling the post mortem cortex. Amyotroph. Lateral Scler., 7, 201-210.
-
(2006)
Amyotroph. Lateral Scler.
, vol.7
, pp. 201-210
-
-
Wang, X.S.1
Simmons, Z.2
Liu, W.3
Boyer, P.J.4
Connor, J.R.5
-
50
-
-
33749056809
-
ALS: a disease of motor neurons and their nonneuronal neighbors
-
Boillee, S., Vande Velde, C. and Cleveland, D.W. (2006) ALS: a disease of motor neurons and their nonneuronal neighbors. Neuron, 52, 39-59.
-
(2006)
Neuron
, vol.52
, pp. 39-59
-
-
Boillee, S.1
Vande Velde, C.2
Cleveland, D.W.3
-
51
-
-
33744798774
-
Onset and progression in inherited ALS determined by motor neurons and microglia
-
Boillee, S., Yamanaka, K., Lobsiger, C.S., Copeland, N.G., Jenkins, N.A., Kassiotis, G., Kollias, G. and Cleveland, D.W. (2006) Onset and progression in inherited ALS determined by motor neurons and microglia. Science, 312, 1389-1392.
-
(2006)
Science
, vol.312
, pp. 1389-1392
-
-
Boillee, S.1
Yamanaka, K.2
Lobsiger, C.S.3
Copeland, N.G.4
Jenkins, N.A.5
Kassiotis, G.6
Kollias, G.7
Cleveland, D.W.8
-
52
-
-
60849093466
-
Current hypotheses for the underlying biology of amyotrophic lateral sclerosis
-
Rothstein, J.D. (2009) Current hypotheses for the underlying biology of amyotrophic lateral sclerosis. Ann. Neurol., 65 (Suppl. 1), S3-S9.
-
(2009)
Ann. Neurol.
, vol.65
, Issue.SUPPL 1
-
-
Rothstein, J.D.1
-
53
-
-
42749097816
-
Crosstalk between astrocytes and motor neurons: what is the message?
-
Van Den Bosch, L. and Robberecht, W. (2008) Crosstalk between astrocytes and motor neurons: what is the message? Exp. Neurol., 211, 1-6.
-
(2008)
Exp. Neurol.
, vol.211
, pp. 1-6
-
-
Van Den Bosch, L.1
Robberecht, W.2
-
54
-
-
33645062075
-
A locus on chromosome 9p confers susceptibility to ALS and frontotemporal dementia
-
Morita, M., Al-Chalabi, A., Andersen, P.M., Hosler, B., Sapp, P., Englund, E., Mitchell, J.E., Habgood, J.J., de Belleroche, J., Xi, J. et al. (2006) A locus on chromosome 9p confers susceptibility to ALS and frontotemporal dementia. Neurology, 66, 839-844.
-
(2006)
Neurology
, vol.66
, pp. 839-844
-
-
Morita, M.1
Al-Chalabi, A.2
Andersen, P.M.3
Hosler, B.4
Sapp, P.5
Englund, E.6
Mitchell, J.E.7
Habgood, J.J.8
de Belleroche, J.9
Xi, J.10
-
55
-
-
33846945446
-
Three families with amyotrophic lateral sclerosis and frontotemporal dementia with evidence of linkage to chromosome 9p
-
Valdmanis, P.N., Dupre, N., Bouchard, J.P., Camu, W., Salachas, F., Meininger, V., Strong, M. and Rouleau, G.A. (2007) Three families with amyotrophic lateral sclerosis and frontotemporal dementia with evidence of linkage to chromosome 9p. Arch. Neurol., 64, 240-245.
-
(2007)
Arch. Neurol.
, vol.64
, pp. 240-245
-
-
Valdmanis, P.N.1
Dupre, N.2
Bouchard, J.P.3
Camu, W.4
Salachas, F.5
Meininger, V.6
Strong, M.7
Rouleau, G.A.8
-
56
-
-
33645069660
-
Familial amyotrophic lateral sclerosis with frontotemporal dementia is linked to a locus on chromosome 9p13 2-21. 3
-
Vance, C., Al-Chalabi, A., Ruddy, D., Smith, B.N., Hu, X., Sreedharan, J., Siddique, T., Schelhaas, H.J., Kusters, B., Troost, D. et al. (2006) Familial amyotrophic lateral sclerosis with frontotemporal dementia is linked to a locus on chromosome 9p13.2-21.3. Brain, 129, 868-876.
-
(2006)
Brain
, vol.129
, pp. 868-876
-
-
Vance, C.1
Al-Chalabi, A.2
Ruddy, D.3
Smith, B.N.4
Hu, X.5
Sreedharan, J.6
Siddique, T.7
Schelhaas, H.J.8
Kusters, B.9
Troost, D.10
-
57
-
-
34247473080
-
Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model
-
Di Giorgio, F.P., Carrasco, M.A., Siao, M.C., Maniatis, T. and Eggan, K. (2007) Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model. Nat. Neurosci., 10, 608-614.
-
(2007)
Nat. Neurosci.
, vol.10
, pp. 608-614
-
-
Di Giorgio, F.P.1
Carrasco, M.A.2
Siao, M.C.3
Maniatis, T.4
Eggan, K.5
-
58
-
-
34247475338
-
Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons
-
Nagai, M., Re, D.B., Nagata, T., Chalazonitis, A., Jessell, T.M., Wichterle, H. and Przedborski, S. (2007) Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons. Nat. Neurosci., 10, 615-622.
-
(2007)
Nat. Neurosci.
, vol.10
, pp. 615-622
-
-
Nagai, M.1
Re, D.B.2
Nagata, T.3
Chalazonitis, A.4
Jessell, T.M.5
Wichterle, H.6
Przedborski, S.7
-
59
-
-
0028284779
-
Motor neuron degeneration in mice that express a human Cu Zn superoxide dismutase mutation
-
Gurney, M.E., Pu, H., Chiu, A.Y., Dal Canto, M.C., Polchow, C.Y., Alexander, D.D., Caliendo, J., Hentati, A., Kwon, Y.W., Deng, H.X. et al. (1994) Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation. Science, 264, 1772-1775.
-
(1994)
Science
, vol.264
, pp. 1772-1775
-
-
Gurney, M.E.1
Pu, H.2
Chiu, A.Y.3
Dal Canto, M.C.4
Polchow, C.Y.5
Alexander, D.D.6
Caliendo, J.7
Hentati, A.8
Kwon, Y.W.9
Deng, H.X.10
-
60
-
-
0034426011
-
Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein
-
Lewis, J., McGowan, E., Rockwood, J., Melrose, H., Nacharaju, P., Van Slegtenhorst, M., Gwinn-Hardy, K., Paul Murphy, M., Baker, M., Yu, X. et al. (2000) Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein. Nat. Genet., 25, 402-405.
-
(2000)
Nat. Genet.
, vol.25
, pp. 402-405
-
-
Lewis, J.1
McGowan, E.2
Rockwood, J.3
Melrose, H.4
Nacharaju, P.5
Van Slegtenhorst, M.6
Gwinn-Hardy, K.7
Paul Murphy, M.8
Baker, M.9
Yu, X.10
-
61
-
-
0033230327
-
Late onset of motor neurons in mice overexpressing wild-type peripherin
-
Beaulieu, J.M., Nguyen, M.D. and Julien, J.P. (1999) Late onset of motor neurons in mice overexpressing wild-type peripherin. J. Cell Biol., 147, 531-544.
-
(1999)
J. Cell Biol.
, vol.147
, pp. 531-544
-
-
Beaulieu, J.M.1
Nguyen, M.D.2
Julien, J.P.3
-
62
-
-
8544222694
-
A frameshift deletion in peripherin gene associated with amyotrophic lateral sclerosis
-
Gros-Louis, F., Lariviere, R., Gowing, G., Laurent, S., Camu, W., Bouchard, J.P., Meininger, V., Rouleau, G.A. and Julien, J.P. (2004) A frameshift deletion in peripherin gene associated with amyotrophic lateral sclerosis. J. Biol. Chem., 279, 45951-45956.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 45951-45956
-
-
Gros-Louis, F.1
Lariviere, R.2
Gowing, G.3
Laurent, S.4
Camu, W.5
Bouchard, J.P.6
Meininger, V.7
Rouleau, G.A.8
Julien, J.P.9
-
63
-
-
0345237912
-
A neurotoxic peripherin splice variant in a mouse model of ALS
-
Robertson, J., Doroudchi, M.M., Nguyen, M.D., Durham, H.D., Strong, M.J., Shaw, G., Julien, J.P. and Mushynski, W.E. (2003) A neurotoxic peripherin splice variant in a mouse model of ALS. J. Cell Biol., 160, 939-949.
-
(2003)
J. Cell Biol.
, vol.160
, pp. 939-949
-
-
Robertson, J.1
Doroudchi, M.M.2
Nguyen, M.D.3
Durham, H.D.4
Strong, M.J.5
Shaw, G.6
Julien, J.P.7
Mushynski, W.E.8
-
64
-
-
33745268197
-
Pathomechanisms of mutant proteins in Charcot-Marie-Tooth disease
-
Niemann, A., Berger, P. and Suter, U. (2006) Pathomechanisms of mutant proteins in Charcot-Marie-Tooth disease. Neuromolecular Med., 8, 217-242.
-
(2006)
Neuromolecular Med.
, vol.8
, pp. 217-242
-
-
Niemann, A.1
Berger, P.2
Suter, U.3
-
65
-
-
0032926368
-
Deletions of the heavy neurofilament subunit tail in amyotrophic lateral sclerosis
-
Al-Chalabi, A., Andersen, P.M., Nilsson, P., Chioza, B., Andersson, J.L., Russ, C., Shaw, C.E., Powell, J.F. and Leigh, P.N. (1999) Deletions of the heavy neurofilament subunit tail in amyotrophic lateral sclerosis. Hum. Mol. Genet., 8, 157-164.
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 157-164
-
-
Al-Chalabi, A.1
Andersen, P.M.2
Nilsson, P.3
Chioza, B.4
Andersson, J.L.5
Russ, C.6
Shaw, C.E.7
Powell, J.F.8
Leigh, P.N.9
-
66
-
-
0028001606
-
Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis
-
Figlewicz, D.A., Krizus, A., Martinoli, M.G., Meininger, V., Dib, M., Rouleau, G.A. and Julien, J.P. (1994) Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis. Hum. Mol. Genet., 3, 1757-1761.
-
(1994)
Hum. Mol. Genet.
, vol.3
, pp. 1757-1761
-
-
Figlewicz, D.A.1
Krizus, A.2
Martinoli, M.G.3
Meininger, V.4
Dib, M.5
Rouleau, G.A.6
Julien, J.P.7
-
67
-
-
0029004898
-
Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis
-
Collard, J.F., Cote, F. and Julien, J.P. (1995) Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis. Nature, 375, 61-64.
-
(1995)
Nature
, vol.375
, pp. 61-64
-
-
Collard, J.F.1
Cote, F.2
Julien, J.P.3
-
68
-
-
0027465098
-
Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: a mouse model of amyotrophic lateral sclerosis
-
Cote, F., Collard, J.F. and Julien, J.P. (1993) Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: a mouse model of amyotrophic lateral sclerosis. Cell, 73, 35-46.
-
(1993)
Cell
, vol.73
, pp. 35-46
-
-
Cote, F.1
Collard, J.F.2
Julien, J.P.3
-
69
-
-
0028116467
-
A mutant neurofilament subunit causes massive, selective motor neuron death: implications for the pathogenesis of human motor neuron disease
-
Lee, M.K., Marszalek, J.R. and Cleveland, D.W. (1994) A mutant neurofilament subunit causes massive, selective motor neuron death: implications for the pathogenesis of human motor neuron disease. Neuron, 13, 975-988.
-
(1994)
Neuron
, vol.13
, pp. 975-988
-
-
Lee, M.K.1
Marszalek, J.R.2
Cleveland, D.W.3
-
70
-
-
0027410516
-
Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease
-
Xu, Z., Cork, L.C., Griffin, J.W. and Cleveland, D.W. (1993) Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease. Cell, 73, 23-33.
-
(1993)
Cell
, vol.73
, pp. 23-33
-
-
Xu, Z.1
Cork, L.C.2
Griffin, J.W.3
Cleveland, D.W.4
-
71
-
-
0141987860
-
The ubiquitin proteasome system in neurodegenerative diseases: sometimes the chicken, sometimes the egg
-
Ciechanover, A. and Brundin, P. (2003) The ubiquitin proteasome system in neurodegenerative diseases: sometimes the chicken, sometimes the egg. Neuron, 40, 427-446.
-
(2003)
Neuron
, vol.40
, pp. 427-446
-
-
Ciechanover, A.1
Brundin, P.2
-
72
-
-
33750089740
-
Degradation of amyotrophic lateral sclerosis-linked mutant Cu,Zn-superoxide dismutase proteins by macroautophagy and the proteasome
-
Kabuta, T., Suzuki, Y. and Wada, K. (2006) Degradation of amyotrophic lateral sclerosis-linked mutant Cu,Zn-superoxide dismutase proteins by macroautophagy and the proteasome. J. Biol. Chem., 281, 30524-30533.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 30524-30533
-
-
Kabuta, T.1
Suzuki, Y.2
Wada, K.3
-
73
-
-
2942708228
-
Mechanism of neurodegenerative disease: role of the ubiquitin proteasome system
-
Petrucelli, L. and Dawson, T.M. (2004) Mechanism of neurodegenerative disease: role of the ubiquitin proteasome system. Ann. Med., 36, 315-320.
-
(2004)
Ann. Med.
, vol.36
, pp. 315-320
-
-
Petrucelli, L.1
Dawson, T.M.2
-
74
-
-
70349987102
-
Taufragmentation, aggregation and clearance: the dual role of lysosomal processing
-
Wang, Y., Martinez-Vicente, M., Kruger, U., Kaushik, S., Wong, E., Mandelkow, E.M., Cuervo, A.M. and Mandelkow, E. (2009) Taufragmentation, aggregation and clearance: the dual role of lysosomal processing. Hum. Mol. Genet, 18, 4153-4170.
-
(2009)
Hum. Mol. Genet
, vol.18
, pp. 4153-4170
-
-
Wang, Y.1
Martinez-Vicente, M.2
Kruger, U.3
Kaushik, S.4
Wong, E.5
Mandelkow, E.M.6
Cuervo, A.M.7
Mandelkow, E.8
-
75
-
-
15044346521
-
Deficient RNA editing of GluR2 and neuronal death in amyotropic lateral sclerosis
-
Kwak, S. and Kawahara, Y. (2005) Deficient RNA editing of GluR2 and neuronal death in amyotropic lateral sclerosis. J. Mol. Med., 83, 110-120.
-
(2005)
J. Mol. Med.
, vol.83
, pp. 110-120
-
-
Kwak, S.1
Kawahara, Y.2
-
76
-
-
1542378930
-
Glutamate receptors: RNA editing and death of motor neurons
-
Kawahara, Y., Ito, K., Sun, H., Aizawa, H., Kanazawa, I. and Kwak, S. (2004) Glutamate receptors: RNA editing and death of motor neurons. Nature, 427, 801.
-
(2004)
Nature
, vol.427
, pp. 801
-
-
Kawahara, Y.1
Ito, K.2
Sun, H.3
Aizawa, H.4
Kanazawa, I.5
Kwak, S.6
-
77
-
-
0032752054
-
Reduction of GluR2 RNA editing, a molecular change that increases calcium influx through AMPA receptors, selective in the spinal ventral gray of patients with amyotrophic lateral sclerosis
-
Takuma, H., Kwak, S., Yoshizawa, T. and Kanazawa, I. (1999) Reduction of GluR2 RNA editing, a molecular change that increases calcium influx through AMPA receptors, selective in the spinal ventral gray of patients with amyotrophic lateral sclerosis. Ann. Neurol., 46, 806-815.
-
(1999)
Ann. Neurol.
, vol.46
, pp. 806-815
-
-
Takuma, H.1
Kwak, S.2
Yoshizawa, T.3
Kanazawa, I.4
-
78
-
-
0033598346
-
Familial dementia caused by polymerization of mutant neuroserpin
-
Davis, R.L., Shrimpton, A.E., Holohan, P.D., Bradshaw, C., Feiglin, D., Collins, G.H., Sonderegger, P., Kinter, J., Becker, L.M., Lacbawan, F. et al. (1999) Familial dementia caused by polymerization of mutant neuroserpin. Nature, 401, 376-379.
-
(1999)
Nature
, vol.401
, pp. 376-379
-
-
Davis, R.L.1
Shrimpton, A.E.2
Holohan, P.D.3
Bradshaw, C.4
Feiglin, D.5
Collins, G.H.6
Sonderegger, P.7
Kinter, J.8
Becker, L.M.9
Lacbawan, F.10
-
79
-
-
0141817940
-
Mitotic-like tau phosphorylation by p25-Cdk5 kinase complex
-
Hamdane, M., Sambo, A.V., Delobel, P., Begard, S., Violleau, A., Delacourte, A., Bertrand, P., Benavides, J. and Buee, L. (2003) Mitotic-like tau phosphorylation by p25-Cdk5 kinase complex. J. Biol. Chem., 278, 34026-34034.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 34026-34034
-
-
Hamdane, M.1
Sambo, A.V.2
Delobel, P.3
Begard, S.4
Violleau, A.5
Delacourte, A.6
Bertrand, P.7
Benavides, J.8
Buee, L.9
-
80
-
-
0036968953
-
Caspase-9 activation and caspase cleavage of tau in the Alzheimer's disease brain
-
Rohn, T.T., Rissman, R.A., Davis, M.C., Kim, Y.E., Cotman, C.W. and Head, E. (2002) Caspase-9 activation and caspase cleavage of tau in the Alzheimer's disease brain. Neurobiol. Dis., 11, 341-354.
-
(2002)
Neurobiol. Dis.
, vol.11
, pp. 341-354
-
-
Rohn, T.T.1
Rissman, R.A.2
Davis, M.C.3
Kim, Y.E.4
Cotman, C.W.5
Head, E.6
-
81
-
-
4143084861
-
Point mutations of the p150 subunit of dynactin (DCTN1) gene in ALS
-
Munch, C., Sedlmeier, R., Meyer, T., Homberg, V., Sperfeld, A.D., Kurt, A., Prudlo, J., Peraus, G., Hanemann, C.O., Stumm, G. et al. (2004) Point mutations of the p150 subunit of dynactin (DCTN1) gene in ALS. Neurology, 63, 724-726.
-
(2004)
Neurology
, vol.63
, pp. 724-726
-
-
Munch, C.1
Sedlmeier, R.2
Meyer, T.3
Homberg, V.4
Sperfeld, A.D.5
Kurt, A.6
Prudlo, J.7
Peraus, G.8
Hanemann, C.O.9
Stumm, G.10
-
82
-
-
0037382240
-
Mutant dynactin in motor neuron disease
-
Puls, I., Jonnakuty, C., LaMonte, B.H., Holzbaur, E.L., Tokito, M., Mann, E., Floeter, M.K., Bidus, K., Drayna, D., Oh, S.J. et al. (2003) Mutant dynactin in motor neuron disease. Nat. Genet., 33, 455-456.
-
(2003)
Nat. Genet.
, vol.33
, pp. 455-456
-
-
Puls, I.1
Jonnakuty, C.2
LaMonte, B.H.3
Holzbaur, E.L.4
Tokito, M.5
Mann, E.6
Floeter, M.K.7
Bidus, K.8
Drayna, D.9
Oh, S.J.10
-
83
-
-
34447550238
-
Interaction between familial amyotrophic lateral sclerosis (ALS)-linked SOD1 mutants and the dynein complex
-
Zhang, F., Strom, A.L., Fukada, K., Lee, S., Hayward, L.J. and Zhu, H. (2007) Interaction between familial amyotrophic lateral sclerosis (ALS)-linked SOD1 mutants and the dynein complex. J. Biol. Chem., 282, 16691-16699.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 16691-16699
-
-
Zhang, F.1
Strom, A.L.2
Fukada, K.3
Lee, S.4
Hayward, L.J.5
Zhu, H.6
-
84
-
-
53049090386
-
Interaction of amyotrophic lateral sclerosis (ALS)-related mutant copper-zinc superoxide dismutase with the dynein-dynactin complex contributes to inclusion formation
-
Strom, A.L., Shi, P., Zhang, F., Gal, J., Kilty, R., Hayward, L.J. and Zhu, H. (2008) Interaction of amyotrophic lateral sclerosis (ALS)-related mutant copper-zinc superoxide dismutase with the dynein-dynactin complex contributes to inclusion formation. J. Biol. Chem., 283, 22795-22805.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 22795-22805
-
-
Strom, A.L.1
Shi, P.2
Zhang, F.3
Gal, J.4
Kilty, R.5
Hayward, L.J.6
Zhu, H.7
-
85
-
-
44849086561
-
FAK/src-family dependent activation of the Ste20-like kinase SLK is required for microtubule-dependent focal adhesion turnover and cell migration
-
Wagner, S., Storbeck, C.J., Roovers, K., Chaar, Z.Y., Kolodziej, P., McKay, M. and Sabourin, L.A. (2008) FAK/src-family dependent activation of the Ste20-like kinase SLK is required for microtubule-dependent focal adhesion turnover and cell migration. PLoS One, 3, e1868.
-
(2008)
PLoS One
, vol.3
-
-
Wagner, S.1
Storbeck, C.J.2
Roovers, K.3
Chaar, Z.Y.4
Kolodziej, P.5
McKay, M.6
Sabourin, L.A.7
-
86
-
-
66749112869
-
A novel role for the Ste20 kinase SLK in adhesion signaling and cell migration
-
Wagner, S.M. and Sabourin, L.A. (2009) A novel role for the Ste20 kinase SLK in adhesion signaling and cell migration. Cell Adh. Migr., 3, 182-184.
-
(2009)
Cell Adh. Migr.
, vol.3
, pp. 182-184
-
-
Wagner, S.M.1
Sabourin, L.A.2
-
87
-
-
0037114989
-
Expression of the Ste20-like kinase SLK during embryonic development and in the murine adult central nervous system
-
Zhang, Y.H., Hume, K., Cadonic, R., Thompson, C., Hakim, A., Staines, W. and Sabourin, L.A. (2002) Expression of the Ste20-like kinase SLK during embryonic development and in the murine adult central nervous system. Brain Res. Dev. Brain Res., 139, 205-215.
-
(2002)
Brain Res. Dev Brain Res.
, vol.139
, pp. 205-215
-
-
Zhang, Y.H.1
Hume, K.2
Cadonic, R.3
Thompson, C.4
Hakim, A.5
Staines, W.6
Sabourin, L.A.7
-
88
-
-
0031822837
-
Tissue microarrays for high-throughput molecular profiling of tumor specimens
-
Kononen, J., Bubendorf, L., Kallioniemi, A., Barlund, M., Schraml, P.,Leighton, S., Torhorst, J., Mihatsch, M.J., Sauter, G. and Kallioniemi, O.P. (1998) Tissue microarrays for high-throughput molecular profiling of tumor specimens. Nat. Med., 4, 844-847.
-
(1998)
Nat. Med.
, vol.4
, pp. 844-847
-
-
Kononen, J.1
Bubendorf, L.2
Kallioniemi, A.3
Barlund, M.4
Schraml, P.5
Leighton, S.6
Torhorst, J.7
Mihatsch, M.J.8
Sauter, G.9
Kallioniemi, O.P.10
-
89
-
-
33745965778
-
Multitissue array review: a chronological description of tissue array techniques, applications and procedures
-
Eguiluz, C., Viguera, E., Millan, L. and Perez, J. (2006) Multitissue array review: a chronological description of tissue array techniques, applications and procedures. Pathol. Res. Pract., 202, 561-568.
-
(2006)
Pathol. Res. Pract.
, vol.202
, pp. 561-568
-
-
Eguiluz, C.1
Viguera, E.2
Millan, L.3
Perez, J.4
-
90
-
-
0037362720
-
Role of kallikrein enzymes in the central nervous system
-
Yousef, G.M., Kishi, T. and Diamandis, E.P. (2003) Role of kallikrein enzymes in the central nervous system. Clin. Chim. Acta, 329,1-8.
-
(2003)
Clin. Chim. Acta
, vol.329
, pp. 1-8
-
-
Yousef, G.M.1
Kishi, T.2
Diamandis, E.P.3
-
91
-
-
0041343303
-
Up-regulation of phosphorylated/activated p70 S6 kinase and its relationship to neurofibrillary pathology in Alzheimer's disease
-
An, W.L., Cowburn, R.F., Li, L., Braak, H., Alafuzoff, I., Iqbal, K., Iqbal, I.G., Winblad, B. and Pei, J.J. (2003) Up-regulation of phosphorylated/activated p70 S6 kinase and its relationship to neurofibrillary pathology in Alzheimer's disease. Am. J. Pathol., 163, 591-607.
-
(2003)
Am. J. Pathol.
, vol.163
, pp. 591-607
-
-
An, W.L.1
Cowburn, R.F.2
Li, L.3
Braak, H.4
Alafuzoff, I.5
Iqbal, K.6
Iqbal, I.G.7
Winblad, B.8
Pei, J.J.9
-
92
-
-
29344460850
-
P70 S6 kinase mediates tau phosphorylation and synthesis
-
Pei, J.J., An, W.L., Zhou, X.W., Nishimura, T., Norberg, J., Benedikz, E., Gotz, J. and Winblad, B. (2006) P70 S6 kinase mediates tau phosphorylation and synthesis. FEBS Lett., 580, 107-114.
-
(2006)
FEBS Lett.
, vol.580
, pp. 107-114
-
-
Pei, J.J.1
An, W.L.2
Zhou, X.W.3
Nishimura, T.4
Norberg, J.5
Benedikz, E.6
Gotz, J.7
Winblad, B.8
-
93
-
-
58049200124
-
Dexras1 interacts with FE65 to regulate FE65-amyloid precursor protein-dependent transcription
-
Lau, K.F., Chan, W.M., Perkinton, M.S., Tudor, E.L., Chang, R.C., Chan, H.Y., McLoughlin, D.M. and Miller, C.C. (2008) Dexras1 interacts with FE65 to regulate FE65-amyloid precursor protein-dependent transcription. J. Biol. Chem., 283, 34728-34737.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 34728-34737
-
-
Lau, K.F.1
Chan, W.M.2
Perkinton, M.S.3
Tudor, E.L.4
Chang, R.C.5
Chan, H.Y.6
McLoughlin, D.M.7
Miller, C.C.8
-
94
-
-
23844538993
-
The pathobiology of amyotrophic lateral sclerosis: a proteinopathy?
-
Strong, M.J., Kesavapany, S. and Pant, H.C. (2005) The pathobiology of amyotrophic lateral sclerosis: a proteinopathy? J. Neuropathol. Exp. Neurol., 64, 649-664.
-
(2005)
J Neuropathol. Exp. Neurol.
, vol.64
, pp. 649-664
-
-
Strong, M.J.1
Kesavapany, S.2
Pant, H.C.3
-
95
-
-
0035882526
-
Attenuated neurodegenerative disease phenotype in tau transgenic mouse lacking neurofilaments
-
Ishihara, T., Higuchi, M., Zhang, B., Yoshiyama, Y., Hong, M., Trojanowski, J.Q. and Lee, V.M. (2001) Attenuated neurodegenerative disease phenotype in tau transgenic mouse lacking neurofilaments. J. Neurosci., 21, 6026-6035.
-
(2001)
J. Neurosci.
, vol.21
, pp. 6026-6035
-
-
Ishihara, T.1
Higuchi, M.2
Zhang, B.3
Yoshiyama, Y.4
Hong, M.5
Trojanowski, J.Q.6
Lee, V.M.7
-
96
-
-
0025438055
-
Altered slow axonal transport and regeneration in a myelin-deficient mutant mouse: the trembler as an in vivo model for Schwann cell-axon interactions
-
de Waegh, S. and Brady, S.T. (1990) Altered slow axonal transport and regeneration in a myelin-deficient mutant mouse: the trembler as an in vivo model for Schwann cell-axon interactions. J. Neurosci., 10, 1855-1865.
-
(1990)
J. Neurosci.
, vol.10
, pp. 1855-1865
-
-
de Waegh, S.1
Brady, S.T.2
-
97
-
-
0028143554
-
Modulation of the axonal microtubule cytoskeleton by myelinating Schwann cells
-
Kirkpatrick, L.L. and Brady, S.T. (1994) Modulation of the axonal microtubule cytoskeleton by myelinating Schwann cells. J. Neurosci., 14, 7440-7450.
-
(1994)
J. Neurosci.
, vol.14
, pp. 7440-7450
-
-
Kirkpatrick, L.L.1
Brady, S.T.2
-
98
-
-
44749087180
-
Cytotoxic activity of 3,3′,4,4′,5 5′-hexahydroxystilbene against breast cancer cells is mediated by induction of p53 and downregulation of mitochondrial superoxide dismutase
-
Murias, M., Luczak, M.W., Niepsuj, A., Krajka-Kuzniak, V., Zielinska-Przyjemska, M., Jagodzinski, P.P., Jager, W., Szekeres, T. and Jodynis-Liebert, J. (2008) Cytotoxic activity of 3,3′,4,4′,5,5′-hexahydroxystilbene against breast cancer cells is mediated by induction of p53 and downregulation of mitochondrial superoxide dismutase. Toxicol. In Vitro, 22, 1361-1370.
-
(2008)
Toxicol. In Vitro
, vol.22
, pp. 1361-1370
-
-
Murias, M.1
Luczak, M.W.2
Niepsuj, A.3
Krajka-Kuzniak, V.4
Zielinska-Przyjemska, M.5
Jagodzinski, P.P.6
Jager, W.7
Szekeres, T.8
Jodynis-Liebert, J.9
-
99
-
-
48249146576
-
Chemosensitisation by manganese superoxide dismutase inhibition is caspase-9 dependent and involves extracellular signal-regulated kinase 1/2
-
Yeung, B.H., Wong, K.Y., Lin, M.C., Wong, C.K., Mashima, T., Tsuruo, T. and Wong, A.S. (2008) Chemosensitisation by manganese superoxide dismutase inhibition is caspase-9 dependent and involves extracellular signal-regulated kinase 1/2. Br J. Cancer, 99, 283-293.
-
(2008)
Br J. Cancer
, vol.99
, pp. 283-293
-
-
Yeung, B.H.1
Wong, K.Y.2
Lin, M.C.3
Wong, C.K.4
Mashima, T.5
Tsuruo, T.6
Wong, A.S.7
-
100
-
-
5044244757
-
R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis
-
Kazanskaya, O., Glinka, A., del Barco Barrantes, I., Stannek, P., Niehrs, C. and Wu, W. (2004) R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis. Dev. Cell, 7, 525-534.
-
(2004)
Dev. Cell
, vol.7
, pp. 525-534
-
-
Kazanskaya, O.1
Glinka, A.2
del Barco Barrantes, I.3
Stannek, P.4
Niehrs, C.5
Wu, W.6
-
101
-
-
48749104088
-
R-Spondin family members regulate the Wnt pathway by a common mechanism
-
Kim, K.A., Wagle, M., Tran, K., Zhan, X., Dixon, M.A., Liu, S., Gros, D., Korver, W., Yonkovich, S., Tomasevic, N. et al. (2008) R-Spondin family members regulate the Wnt pathway by a common mechanism. Mol. Biol. Cell, 19, 2588-2596.
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 2588-2596
-
-
Kim, K.A.1
Wagle, M.2
Tran, K.3
Zhan, X.4
Dixon, M.A.5
Liu, S.6
Gros, D.7
Korver, W.8
Yonkovich, S.9
Tomasevic, N.10
-
102
-
-
58949095497
-
Gene expression analysis of neural cells and tissues using DNA microarrays
-
Chapter 4 Unit
-
Karsten, S.L., Kudo, L.C. and Geschwind, D.H. (2008) Gene expression analysis of neural cells and tissues using DNA microarrays. Curr. Protoc. Neurosci., Chapter 4, Unit 4 28.
-
(2008)
Curr. Protoc. Neurosci.
, vol.4
, pp. 28
-
-
Karsten, S.L.1
Kudo, L.C.2
Geschwind, D.H.3
-
103
-
-
33749063646
-
Probing the transcriptome of neuronal cell types
-
Nelson, S.B., Hempel, C. and Sugino, K. (2006) Probing the transcriptome of neuronal cell types. Curr. Opin. Neurobiol., 16, 571-576.
-
(2006)
Curr. Opin. Neurobiol.
, vol.16
, pp. 571-576
-
-
Nelson, S.B.1
Hempel, C.2
Sugino, K.3
-
104
-
-
33745144588
-
The problem of neuronal cell types: a physiological genomics approach
-
Nelson, S.B., Sugino, K. and Hempel, C.M. (2006) The problem of neuronal cell types: a physiological genomics approach. Trends Neurosci., 29, 339-345.
-
(2006)
Trends Neurosci.
, vol.29
, pp. 339-345
-
-
Nelson, S.B.1
Sugino, K.2
Hempel, C.M.3
-
106
-
-
50849083264
-
Retrograde axonal transport and motor neuron disease
-
Strom, A.L., Gal, J., Shi, P., Kasarskis, E.J., Hayward, L.J. and Zhu, H. (2008) Retrograde axonal transport and motor neuron disease. J. Neurochem., 106, 495-505.
-
(2008)
J. Neurochem.
, vol.106
, pp. 495-505
-
-
Strom, A.L.1
Gal, J.2
Shi, P.3
Kasarskis, E.J.4
Hayward, L.J.5
Zhu, H.6
-
107
-
-
34548299711
-
Defective axonal transport in motor neuron disease
-
El-Kadi, A.M., Soura, V. and Hafezparast, M. (2007) Defective axonal transport in motor neuron disease. J. Neurosci. Res., 85, 2557-2566.
-
(2007)
J. Neurosci. Res.
, vol.85
, pp. 2557-2566
-
-
El-Kadi, A.M.1
Soura, V.2
Hafezparast, M.3
-
108
-
-
2342561865
-
Motor neurons rely on motor proteins
-
Holzbaur, E.L. (2004) Motor neurons rely on motor proteins. Trends Cell Biol., 14, 233-240.
-
(2004)
Trends Cell Biol.
, vol.14
, pp. 233-240
-
-
Holzbaur, E.L.1
-
109
-
-
0037198698
-
Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive degeneration
-
LaMonte, B.H., Wallace, K.E., Holloway, B.A., Shelly, S.S., Ascano, J., Tokito, M., Van Winkle, T., Howland, D.S. and Holzbaur, E.L. (2002) Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive degeneration. Neuron, 34, 715-727.
-
(2002)
Neuron
, vol.34
, pp. 715-727
-
-
LaMonte, B.H.1
Wallace, K.E.2
Holloway, B.A.3
Shelly, S.S.4
Ascano, J.5
Tokito, M.6
Van Winkle, T.7
Howland, D.S.8
Holzbaur, E.L.9
-
110
-
-
0037734370
-
Mutations in dynein link motor neuron degeneration to defects in retrograde transport
-
Hafezparast, M., Klocke, R., Ruhrberg, C., Marquardt, A., Ahmad-Annuar, A., Bowen, S., Lalli, G., Witherden, A.S., Hummerich, H., Nicholson, S. et al. (2003) Mutations in dynein link motor neuron degeneration to defects in retrograde transport. Science, 300, 808-812.
-
(2003)
Science
, vol.300
, pp. 808-812
-
-
Hafezparast, M.1
Klocke, R.2
Ruhrberg, C.3
Marquardt, A.4
Ahmad-Annuar, A.5
Bowen, S.6
Lalli, G.7
Witherden, A.S.8
Hummerich, H.9
Nicholson, S.10
-
111
-
-
0023219957
-
Fast axonal transport in amyotrophic lateral sclerosis: an intra-axonal organelle traffic analysis
-
Breuer, A.C., Lynn, M.P., Atkinson, M.B., Chou, S.M., Wilbourn, A.J., Marks, K.E., Culver, J.E. and Fleegler, E.J. (1987) Fast axonal transport in amyotrophic lateral sclerosis: an intra-axonal organelle traffic analysis. Neurology, 37, 738-748.
-
(1987)
Neurology
, vol.37
, pp. 738-748
-
-
Breuer, A.C.1
Lynn, M.P.2
Atkinson, M.B.3
Chou, S.M.4
Wilbourn, A.J.5
Marks, K.E.6
Culver, J.E.7
Fleegler, E.J.8
-
112
-
-
35548991459
-
Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content
-
De Vos, K.J., Chapman, A.L., Tennant, M.E., Manser, C., Tudor, E.L., Lau, K.F., Brownlees, J., Ackerley, S., Shaw, P.J., McLoughlin, D.M. et al. (2007) Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content. Hum. Mol. Genet., 16, 2720-2728.
-
(2007)
Hum. Mol. Genet.
, vol.16
, pp. 2720-2728
-
-
De Vos, K.J.1
Chapman, A.L.2
Tennant, M.E.3
Manser, C.4
Tudor, E.L.5
Lau, K.F.6
Brownlees, J.7
Ackerley, S.8
Shaw, P.J.9
McLoughlin, D.M.10
-
113
-
-
0029812897
-
Impairment of fast axonal transport in the proximal axons of anterior horn neurons in amyotrophic lateral sclerosis
-
Sasaki, S. and Iwata, M. (1996) Impairment of fast axonal transport in the proximal axons of anterior horn neurons in amyotrophic lateral sclerosis. Neurology, 47, 535-540.
-
(1996)
Neurology
, vol.47
, pp. 535-540
-
-
Sasaki, S.1
Iwata, M.2
-
114
-
-
0033826065
-
Differential screening of mutated SOD1 transgenic mice reveals early up-regulation of a fast axonal transport component in spinal cord motor neurons
-
Dupuis, L., de Tapia, M., Rene, F., Lutz-Bucher, B., Gordon, J.W., Mercken, L., Pradier, L. and Loeffler, J.P. (2000) Differential screening of mutated SOD1 transgenic mice reveals early up-regulation of a fast axonal transport component in spinal cord motor neurons. Neurobiol. Dis., 7, 274-285.
-
(2000)
Neurobiol. Dis.
, vol.7
, pp. 274-285
-
-
Dupuis, L.1
de Tapia, M.2
Rene, F.3
Lutz-Bucher, B.4
Gordon, J.W.5
Mercken, L.6
Pradier, L.7
Loeffler, J.P.8
-
115
-
-
23644437653
-
Impairment of axonal transport in the axon hillock and the initial segment of anterior horn neurons in transgenic mice with a G93A mutant SOD1 gene
-
Sasaki, S., Warita, H., Abe, K. and Iwata, M. (2005) Impairment of axonal transport in the axon hillock and the initial segment of anterior horn neurons in transgenic mice with a G93A mutant SOD1 gene. Acta Neuropathol., 110, 48-56.
-
(2005)
Acta Neuropathol.
, vol.110
, pp. 48-56
-
-
Sasaki, S.1
Warita, H.2
Abe, K.3
Iwata, M.4
-
116
-
-
0033585832
-
Selective impairment of fast anterograde axonal transport in the peripheral nerves of asymptomatic transgenic mice with a G93A mutant SOD1 gene
-
Warita, H., Itoyama, Y. and Abe, K. (1999) Selective impairment of fast anterograde axonal transport in the peripheral nerves of asymptomatic transgenic mice with a G93A mutant SOD1 gene. Brain Res., 819, 120-131.
-
(1999)
Brain Res.
, vol.819
, pp. 120-131
-
-
Warita, H.1
Itoyama, Y.2
Abe, K.3
-
117
-
-
0033366384
-
Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons
-
Williamson, T.L. and Cleveland, D.W. (1999) Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons. Nat. Neurosci., 2, 50-56.
-
(1999)
Nat. Neurosci.
, vol.2
, pp. 50-56
-
-
Williamson, T.L.1
Cleveland, D.W.2
-
118
-
-
0030817291
-
Neurofilaments and orthograde transport are reduced in ventral root axons of transgenic mice that express human SOD1 with a G93A mutation
-
Zhang, B., Tu, P., Abtahian, F., Trojanowski, J.Q. and Lee, V.M. (1997) Neurofilaments and orthograde transport are reduced in ventral root axons of transgenic mice that express human SOD1 with a G93A mutation. J. Cell Biol., 139, 1307-1315.
-
(1997)
J. Cell Biol.
, vol.139
, pp. 1307-1315
-
-
Zhang, B.1
Tu, P.2
Abtahian, F.3
Trojanowski, J.Q.4
Lee, V.M.5
-
119
-
-
2442642836
-
Retarded axonal transport of R406W mutant tau in transgenic mice with a neurodegenerative tauopathy
-
Zhang, B., Higuchi, M., Yoshiyama, Y., Ishihara, T., Forman, M.S., Martinez, D., Joyce, S., Trojanowski, J.Q. and Lee, V.M. (2004) Retarded axonal transport of R406W mutant tau in transgenic mice with a neurodegenerative tauopathy. J. Neurosci., 24, 4657-4667.
-
(2004)
J. Neurosci.
, vol.24
, pp. 4657-4667
-
-
Zhang, B.1
Higuchi, M.2
Yoshiyama, Y.3
Ishihara, T.4
Forman, M.S.5
Martinez, D.6
Joyce, S.7
Trojanowski, J.Q.8
Lee, V.M.9
-
120
-
-
34548829896
-
Early axonopathy preceding neurofibrillary tangles in mutant tau transgenic mice
-
Leroy, K., Bretteville, A., Schindowski, K., Gilissen, E., Authelet, M., De Decker, R., Yilmaz, Z., Buee, L. and Brion, J.P. (2007) Early axonopathy preceding neurofibrillary tangles in mutant tau transgenic mice. Am. J. Pathol., 171, 976-992.
-
(2007)
Am. J. Pathol.
, vol.171
, pp. 976-992
-
-
Leroy, K.1
Bretteville, A.2
Schindowski, K.3
Gilissen, E.4
Authelet, M.5
De Decker, R.6
Yilmaz, Z.7
Buee, L.8
Brion, J.P.9
-
121
-
-
57349172663
-
Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia
-
Ittner, L.M., Fath, T., Ke, Y.D., Bi, M., van Eersel, J., Li, K.M., Gunning, P. and Gotz, J. (2008) Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia. Proc. Natl Acad. Sci. USA, 105, 15997-16002.
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 15997-16002
-
-
Ittner, L.M.1
Fath, T.2
Ke, Y.D.3
Bi, M.4
van Eersel, J.5
Li, K.M.6
Gunning, P.7
Gotz, J.8
-
122
-
-
34948859426
-
Aging attenuates dynactin-dynein interaction: down-regulation of dynein causes accumulation of endogenous tau and amyloid precursor protein in human neuroblastoma cells
-
Kimura, N., Imamura, O., Ono, F. and Terao, K. (2007) Aging attenuates dynactin-dynein interaction: down-regulation of dynein causes accumulation of endogenous tau and amyloid precursor protein in human neuroblastoma cells. J. Neurosci. Res., 85, 2909-2916.
-
(2007)
J. Neurosci. Res.
, vol.85
, pp. 2909-2916
-
-
Kimura, N.1
Imamura, O.2
Ono, F.3
Terao, K.4
-
123
-
-
39549117998
-
Axonal transport rates in vivo are unaffected by tau deletion or overexpression in mice
-
Yuan, A., Kumar, A., Peterhoff, C., Duff, K. and Nixon, R.A. (2008) Axonal transport rates in vivo are unaffected by tau deletion or overexpression in mice. J. Neurosci., 28, 1682-1687.
-
(2008)
J. Neurosci.
, vol.28
, pp. 1682-1687
-
-
Yuan, A.1
Kumar, A.2
Peterhoff, C.3
Duff, K.4
Nixon, R.A.5
-
124
-
-
27644558934
-
Heterozygous R1101K mutation of the DCTN1 gene in a family with ALS and FTD
-
Munch, C., Rosenbohm, A., Sperfeld, A.D., Uttner, I., Reske, S., Krause, B.J., Sedlmeier, R., Meyer, T., Hanemann, C.O., Stumm, G. et al. (2005) Heterozygous R1101K mutation of the DCTN1 gene in a family with ALS and FTD. Ann. Neurol., 58, 777-780.
-
(2005)
Ann. Neurol.
, vol.58
, pp. 777-780
-
-
Munch, C.1
Rosenbohm, A.2
Sperfeld, A.D.3
Uttner, I.4
Reske, S.5
Krause, B.J.6
Sedlmeier, R.7
Meyer, T.8
Hanemann, C.O.9
Stumm, G.10
-
125
-
-
20944448536
-
Distal spinal and bulbar muscular atrophy caused by dynactin mutation
-
Puls, I., Oh, S.J., Sumner, C.J., Wallace, K.E., Floeter, M.K., Mann, E.A., Kennedy, W.R., Wendelschafer-Crabb, G., Vortmeyer, A., Powers, R. et al. (2005) Distal spinal and bulbar muscular atrophy caused by dynactin mutation. Ann. Neurol., 57, 687-694.
-
(2005)
Ann. Neurol.
, vol.57
, pp. 687-694
-
-
Puls, I.1
Oh, S.J.2
Sumner, C.J.3
Wallace, K.E.4
Floeter, M.K.5
Mann, E.A.6
Kennedy, W.R.7
Wendelschafer-Crabb, G.8
Vortmeyer, A.9
Powers, R.10
-
126
-
-
59149097039
-
DCTN1 mutations in Perry syndrome
-
Farrer, M.J., Hulihan, M.M., Kachergus, J.M., Dachsel, J.C., Stoessl, A.J., Grantier, L.L., Calne, S., Calne, D.B., Lechevalier, B., Chapon, F. et al. (2009) DCTN1 mutations in Perry syndrome. Nat. Genet., 41, 163-165.
-
(2009)
Nat. Genet.
, vol.41
, pp. 163-165
-
-
Farrer, M.J.1
Hulihan, M.M.2
Kachergus, J.M.3
Dachsel, J.C.4
Stoessl, A.J.5
Grantier, L.L.6
Calne, S.7
Calne, D.B.8
Lechevalier, B.9
Chapon, F.10
-
127
-
-
35649028013
-
Interaction of tau protein with the dynactin complex
-
Magnani, E., Fan, J., Gasparini, L., Golding, M., Williams, M., Schiavo, G., Goedert, M., Amos, L.A. and Spillantini, M.G. (2007) Interaction of tau protein with the dynactin complex. EMBO J., 26, 4546-4554.
-
(2007)
EMBO J.
, vol.26
, pp. 4546-4554
-
-
Magnani, E.1
Fan, J.2
Gasparini, L.3
Golding, M.4
Williams, M.5
Schiavo, G.6
Goedert, M.7
Amos, L.A.8
Spillantini, M.G.9
-
128
-
-
40849144062
-
Array-based gene discovery with three unrelated subjects shows SCARB2/LIMP-2 deficiency causes myoclonus epilepsy and glomerulosclerosis
-
Berkovic, S.F., Dibbens, L.M., Oshlack, A., Silver, J.D., Katerelos, M., Vears, D.F., Lullmann-Rauch, R., Blanz, J., Zhang, K.W., Stankovich, J. et al. (2008) Array-based gene discovery with three unrelated subjects shows SCARB2/LIMP-2 deficiency causes myoclonus epilepsy and glomerulosclerosis. Am. J. Hum. Genet., 82, 673-684.
-
(2008)
Am. J. Hum. Genet.
, vol.82
, pp. 673-684
-
-
Berkovic, S.F.1
Dibbens, L.M.2
Oshlack, A.3
Silver, J.D.4
Katerelos, M.5
Vears, D.F.6
Lullmann-Rauch, R.7
Blanz, J.8
Zhang, K.W.9
Stankovich, J.10
-
129
-
-
28144460266
-
Comparative genomics and gene expression analysis identifies BBS9, a new Bardet-Biedl syndrome gene
-
Nishimura, D.Y., Swiderski, R.E., Searby, C.C., Berg, E.M., Ferguson, A.L., Hennekam, R., Merin, S., Weleber, R.G., Biesecker, L.G., Stone, E.M. et al. (2005) Comparative genomics and gene expression analysis identifies BBS9, a new Bardet-Biedl syndrome gene. Am. J. Hum. Genet., 77, 1021-1033.
-
(2005)
Am. J. Hum. Genet.
, vol.77
, pp. 1021-1033
-
-
Nishimura, D.Y.1
Swiderski, R.E.2
Searby, C.C.3
Berg, E.M.4
Ferguson, A.L.5
Hennekam, R.6
Merin, S.7
Weleber, R.G.8
Biesecker, L.G.9
Stone, E.M.10
-
130
-
-
0034615550
-
Tissue inhibitors of metalloproteinases: evolution, structure and function
-
Brew, K., Dinakarpandian, D. and Nagase, H. (2000) Tissue inhibitors of metalloproteinases: evolution, structure and function. Biochim. Biophys. Acta, 1477, 267-283.
-
(2000)
Biochim. Biophys. Acta
, vol.1477
, pp. 267-283
-
-
Brew, K.1
Dinakarpandian, D.2
Nagase, H.3
-
131
-
-
0034749944
-
Matrix metalloproteinases: multifunctional effectors of inflammation in multiple sclerosis and bacterial meningitis
-
Leppert, D., Lindberg, R.L., Kappos, L. and Leib, S.L. (2001) Matrix metalloproteinases: multifunctional effectors of inflammation in multiple sclerosis and bacterial meningitis. Brain Res. Brain Res. Rev., 36, 249-257.
-
(2001)
Brain Res. Brain Res. Rev.
, vol.36
, pp. 249-257
-
-
Leppert, D.1
Lindberg, R.L.2
Kappos, L.3
Leib, S.L.4
-
132
-
-
59349113948
-
Diverse roles of matrix metalloproteinases and tissue inhibitors of metalloproteinases in neuroinflammation and cerebral ischemia
-
Candelario-Jalil, E., Yang, Y. and Rosenberg, G.A. (2009) Diverse roles of matrix metalloproteinases and tissue inhibitors of metalloproteinases in neuroinflammation and cerebral ischemia. Neuroscience, 158, 983-994.
-
(2009)
Neuroscience
, vol.158
, pp. 983-994
-
-
Candelario-Jalil, E.1
Yang, Y.2
Rosenberg, G.A.3
-
133
-
-
0034626855
-
Matrix metalloproteinase-9 is elevated in serum of patients with amyotrophic lateral sclerosis
-
Beuche, W., Yushchenko, M., Mader, M., Maliszewska, M., Felgenhauer, K. and Weber, F. (2000) Matrix metalloproteinase-9 is elevated in serum of patients with amyotrophic lateral sclerosis. Neuroreport, 11, 3419-3422.
-
(2000)
Neuroreport
, vol.11
, pp. 3419-3422
-
-
Beuche, W.1
Yushchenko, M.2
Mader, M.3
Maliszewska, M.4
Felgenhauer, K.5
Weber, F.6
-
134
-
-
74549186988
-
Matrix metalloproteinases and their tissue inhibitors in serum and cerebrospinal fluid of patients with amyotrophic lateral sclerosis
-
10.1111/j.1468-1331.2009.02775.x
-
Niebroj-Dobosz, I., Janik, P., Sokolowska, B. and Kwiecinski, H. (2009) Matrix metalloproteinases and their tissue inhibitors in serum and cerebrospinal fluid of patients with amyotrophic lateral sclerosis. Eur. J. Neurol, 10.1111/j.1468-1331.2009.02775.x.
-
(2009)
Eur. J. Neurol
-
-
Niebroj-Dobosz, I.1
Janik, P.2
Sokolowska, B.3
Kwiecinski, H.4
-
135
-
-
77955015789
-
Evaluation of matrix metalloproteinases in serum of patients with amyotrophic lateral sclerosis with pattern recognition methods
-
Sokolowska, B., Jozwik, A., Niebroj-Dobosz, I., Janik, P. and Kwiecinski, H. (2009) Evaluation of matrix metalloproteinases in serum of patients with amyotrophic lateral sclerosis with pattern recognition methods. J. Physiol. Pharmacol., 60 (Suppl 5), 117-120.
-
(2009)
J. Physiol. Pharmacol.
, vol.60
, Issue.SUPPL 5
, pp. 117-120
-
-
Sokolowska, B.1
Jozwik, A.2
Niebroj-Dobosz, I.3
Janik, P.4
Kwiecinski, H.5
-
136
-
-
10744226623
-
Matrix metalloproteinase expression during experimental autoimmune encephalomyelitis and effects of a combined matrix metalloproteinase and tumour necrosis factor-alpha inhibitor
-
Clements, J.M., Cossins, J.A., Wells, G.M., Corkill, D.J., Helfrich, K., Wood, L.M., Pigott, R., Stabler, G., Ward, G.A., Gearing, A.J. et al. (1997) Matrix metalloproteinase expression during experimental autoimmune encephalomyelitis and effects of a combined matrix metalloproteinase and tumour necrosis factor-alpha inhibitor. J. Neuroimmunol., 74, 85-94.
-
(1997)
J. Neuroimmunol.
, vol.74
, pp. 85-94
-
-
Clements, J.M.1
Cossins, J.A.2
Wells, G.M.3
Corkill, D.J.4
Helfrich, K.5
Wood, L.M.6
Pigott, R.7
Stabler, G.8
Ward, G.A.9
Gearing, A.J.10
-
137
-
-
0035328844
-
Tissue inhibitor of metalloproteinases-4 inhibits but does not support the activation of gelatinase A via efficient inhibition of membrane type 1-matrix metalloproteinase
-
Bigg, H.F., Morrison, C.J., Butler, G.S., Bogoyevitch, M.A., Wang, Z., Soloway, P.D. and Overall, C.M. (2001) Tissue inhibitor of metalloproteinases-4 inhibits but does not support the activation of gelatinase A via efficient inhibition of membrane type 1-matrix metalloproteinase. Cancer Res., 61, 3610-3618.
-
(2001)
Cancer Res.
, vol.61
, pp. 3610-3618
-
-
Bigg, H.F.1
Morrison, C.J.2
Butler, G.S.3
Bogoyevitch, M.A.4
Wang, Z.5
Soloway, P.D.6
Overall, C.M.7
-
138
-
-
0032006878
-
Matrix metalloproteinases and diseases of the CNS
-
Yong, V.W., Krekoski, C.A., Forsyth, P.A., Bell, R. and Edwards, D.R. (1998) Matrix metalloproteinases and diseases of the CNS. Trends Neurosci., 21, 75-80.
-
(1998)
Trends Neurosci.
, vol.21
, pp. 75-80
-
-
Yong, V.W.1
Krekoski, C.A.2
Forsyth, P.A.3
Bell, R.4
Edwards, D.R.5
-
139
-
-
42649107468
-
Tissue inhibitor of metalloproteinases-3 (TIMP-3) expression isincreased during serum deprivation-induced neuronal apoptosis in vitro and in the G93A mouse model of amyotrophic lateral sclerosis: apotential modulator of Fas-mediated apoptosis
-
Lee, J.K., Shin, J.H., Suh, J., Choi, I.S., Ryu, K.S. and Gwag, B.J. (2008) Tissue inhibitor of metalloproteinases-3 (TIMP-3) expression isincreased during serum deprivation-induced neuronal apoptosis in vitro and in the G93A mouse model of amyotrophic lateral sclerosis: apotential modulator of Fas-mediated apoptosis. Neurobiol. Dis., 30, 174-185.
-
(2008)
Neurobiol. Dis.
, vol.30
, pp. 174-185
-
-
Lee, J.K.1
Shin, J.H.2
Suh, J.3
Choi, I.S.4
Ryu, K.S.5
Gwag, B.J.6
-
140
-
-
0034333458
-
Differential spatial distribution and temporal regulation of tissue inhibitor of metalloproteinase mRNA expression during rat central nervous system development
-
Fager, N. and Jaworski, D.M. (2000) Differential spatial distribution and temporal regulation of tissue inhibitor of metalloproteinase mRNA expression during rat central nervous system development. Mech. Dev., 98, 105-109.
-
(2000)
Mech. Dev.
, vol.98
, pp. 105-109
-
-
Fager, N.1
Jaworski, D.M.2
-
141
-
-
12244291232
-
Tissue inhibitors of matrix metalloproteinases are elevated in cerebrospinal fluid of neurodegene-rative diseases
-
Lorenzl, S., Albers, D.S., LeWitt, P.A., Chirichigno, J.W., Hilgenberg, S.L., Cudkowicz, M.E. and Beal, M.F. (2003) Tissue inhibitors of matrix metalloproteinases are elevated in cerebrospinal fluid of neurodegene-rative diseases. J. Neurol. Sci., 207, 71-76.
-
(2003)
J. Neurol. Sci.
, vol.207
, pp. 71-76
-
-
Lorenzl, S.1
Albers, D.S.2
LeWitt, P.A.3
Chirichigno, J.W.4
Hilgenberg, S.L.5
Cudkowicz, M.E.6
Beal, M.F.7
-
142
-
-
4944246703
-
Treatment of experimental autoimmune encephalomyelitis with a neurotropic alphavirus vector expressing tissue inhibitor of metalloproteinase-2
-
Nygardas, P.T., Gronberg, S.A., Heikkila, J., Joronen, K., Sorsa, T. and Hinkkanen, A.E. (2004) Treatment of experimental autoimmune encephalomyelitis with a neurotropic alphavirus vector expressing tissue inhibitor of metalloproteinase-2. Scand. J. Immunol., 60, 372-381.
-
(2004)
Scand. J. Immunol.
, vol.60
, pp. 372-381
-
-
Nygardas, P.T.1
Gronberg, S.A.2
Heikkila, J.3
Joronen, K.4
Sorsa, T.5
Hinkkanen, A.E.6
-
143
-
-
70450224638
-
The neuroprotective role of tissue inhibitor of metalloproteinase-2 in MPP+- or 6-OHDA-treated SK-N-BE(2)C and SH-SY5Y human neuroblastoma cells
-
Kim, S.Y., Woo, M.S., Park, J.S., Hyun, J.W., Kim, Y.S. and Kim, H.S. (2010) The neuroprotective role of tissue inhibitor of metalloproteinase-2 in MPP+- or 6-OHDA-treated SK-N-BE(2)C and SH-SY5Y human neuroblastoma cells. Neurosci. Lett., 468, 136-140.
-
(2010)
Neurosci. Lett.
, vol.468
, pp. 136-140
-
-
Kim, S.Y.1
Woo, M.S.2
Park, J.S.3
Hyun, J.W.4
Kim, Y.S.5
Kim, H.S.6
-
144
-
-
57149120501
-
Biomarkers in amyotrophic lateral sclerosis
-
Turner, M.R., Kiernan, M.C., Leigh, P.N. and Talbot, K. (2009) Biomarkers in amyotrophic lateral sclerosis. Lancet Neurol., 8, 94-109.
-
(2009)
Lancet Neurol.
, vol.8
, pp. 94-109
-
-
Turner, M.R.1
Kiernan, M.C.2
Leigh, P.N.3
Talbot, K.4
-
145
-
-
70450180994
-
Prognostic factors in ALS: A critical review
-
Chio, A., Logroscino, G., Hardiman, O., Swingler, R., Mitchell, D., Beghi, E. and Traynor, B.G. (2009) Prognostic factors in ALS: A critical review. Amyotroph. Lateral Scler., 10, 310-323.
-
(2009)
Amyotroph. Lateral Scler.
, vol.10
, pp. 310-323
-
-
Chio, A.1
Logroscino, G.2
Hardiman, O.3
Swingler, R.4
Mitchell, D.5
Beghi, E.6
Traynor, B.G.7
-
146
-
-
73949091031
-
Brain and blood microRNA expression profiling of ischemic stroke, intracerebral hemorrhage, and kainate seizures
-
Liu, D.Z., Tian, Y., Ander, B.P., Xu, H., Stamova, B.S., Zhan, X., Turner, R.J., Jickling, G. and Sharp, F.R. (2010) Brain and blood microRNA expression profiling of ischemic stroke, intracerebral hemorrhage, and kainate seizures. J. Cereb. Blood Flow Metab., 30, 92-101.
-
(2010)
J. Cereb. Blood Flow Metab.
, vol.30
, pp. 92-101
-
-
Liu, D.Z.1
Tian, Y.2
Ander, B.P.3
Xu, H.4
Stamova, B.S.5
Zhan, X.6
Turner, R.J.7
Jickling, G.8
Sharp, F.R.9
-
147
-
-
73949087215
-
Brief focal cerebral ischemia that simulates transient ischemic attacks in humans regulates gene expression in rat peripheral blood
-
Zhan, X., Ander, B.P., Jickling, G., Turner, R., Stamova, B., Xu, H., Liu, D., Davis, R.R. and Sharp, F.R. (2010) Brief focal cerebral ischemia that simulates transient ischemic attacks in humans regulates gene expression in rat peripheral blood. J. Cereb. Blood Flow Metab., 30, 110-118.
-
(2010)
J. Cereb. Blood Flow Metab.
, vol.30
, pp. 110-118
-
-
Zhan, X.1
Ander, B.P.2
Jickling, G.3
Turner, R.4
Stamova, B.5
Xu, H.6
Liu, D.7
Davis, R.R.8
Sharp, F.R.9
-
148
-
-
37349002507
-
Gene expression changes in children with autism
-
Gregg, J.P., Lit, L., Baron, C.A., Hertz-Picciotto, I., Walker, W., Davis, R.A., Croen, L.A., Ozonoff, S., Hansen, R., Pessah, I.N. et al. (2008) Gene expression changes in children with autism. Genomics, 91, 22-29.
-
(2008)
Genomics
, vol.91
, pp. 22-29
-
-
Gregg, J.P.1
Lit, L.2
Baron, C.A.3
Hertz-Picciotto, I.4
Walker, W.5
Davis, R.A.6
Croen, L.A.7
Ozonoff, S.8
Hansen, R.9
Pessah, I.N.10
-
149
-
-
78650548973
-
Correlations of gene expression with blood lead levels in children with autism compared to typically developing controls
-
10.1007/s12640-009-9126-x
-
Tian, Y., Green, P.G., Stamova, B., Hertz-Picciotto, I., Pessah, I.N., Hansen, R., Yang, X., Gregg, J.P., Ashwood, P., Jickling, G. et al. (2009) Correlations of gene expression with blood lead levels in children with autism compared to typically developing controls. Neurotox. Res., 10.1007/s12640-009-9126-x.
-
(2009)
Neurotox. Res.
-
-
Tian, Y.1
Green, P.G.2
Stamova, B.3
Hertz-Picciotto, I.4
Pessah, I.N.5
Hansen, R.6
Yang, X.7
Gregg, J.P.8
Ashwood, P.9
Jickling, G.10
-
150
-
-
77953524192
-
The multiple sclerosis whole blood mRNA transcriptome and genetic associations indicate dysregulation of specific T cell pathways in pathogenesis
-
10.1093/hmg/ddq090
-
Gandhi, K.S., McKay, F.C., Cox, M., Riveros, C., Armstrong, N., Heard, R.N., Vucic, S., Williams, D.W., Stankovich, J., Brown, M. et al. (2010) The multiple sclerosis whole blood mRNA transcriptome and genetic associations indicate dysregulation of specific T cell pathways in pathogenesis. Hum. Mol. Genet, 10.1093/hmg/ddq090.
-
(2010)
Hum. Mol. Genet
-
-
Gandhi, K.S.1
McKay, F.C.2
Cox, M.3
Riveros, C.4
Armstrong, N.5
Heard, R.N.6
Vucic, S.7
Williams, D.W.8
Stankovich, J.9
Brown, M.10
-
151
-
-
57749182022
-
Age-related gene expression in Tourette syndrome
-
Lit, L., Enstrom, A., Sharp, F.R. and Gilbert, D.L. (2009) Age-related gene expression in Tourette syndrome. J. Psychiatr. Res., 43, 319-330.
-
(2009)
J. Psychiatr. Res.
, vol.43
, pp. 319-330
-
-
Lit, L.1
Enstrom, A.2
Sharp, F.R.3
Gilbert, D.L.4
-
152
-
-
65549141230
-
Gene expression as peripheralbiomarkers for sporadic Alzheimer's disease
-
Grunblatt, E., Bartl, J., Zehetmayer, S., Ringel, T.M., Bauer, P., Riederer, P. and Jacob, C.P. (2009) Gene expression as peripheralbiomarkers for sporadic Alzheimer's disease. J. Alzheimers Dis., 16, 627-634.
-
(2009)
J. Alzheimers Dis.
, vol.16
, pp. 627-634
-
-
Grunblatt, E.1
Bartl, J.2
Zehetmayer, S.3
Ringel, T.M.4
Bauer, P.5
Riederer, P.6
Jacob, C.P.7
-
153
-
-
77951766920
-
From transcriptome analysis to therapeutic anti-CD40L treatment in the SOD1 model of amyotrophic lateral sclerosis
-
Lincecum, J.M., Vieira, F.G., Wang, M.Z., Thompson, K., De Zutter, G.S., Kidd, J., Moreno, A., Sanchez, R., Carrion, I.J., Levine, B.A. et al. (2010) From transcriptome analysis to therapeutic anti-CD40L treatment in the SOD1 model of amyotrophic lateral sclerosis. Nat. Genet., 42, 392-399.
-
(2010)
Nat. Genet.
, vol.42
, pp. 392-399
-
-
Lincecum, J.M.1
Vieira, F.G.2
Wang, M.Z.3
Thompson, K.4
De Zutter, G.S.5
Kidd, J.6
Moreno, A.7
Sanchez, R.8
Carrion, I.J.9
Levine, B.A.10
-
154
-
-
70349570737
-
Weighted gene co-expression network analysis of the peripheral blood from Amyotrophic Lateral Sclerosis patients
-
Saris, C.G., Horvath, S., van Vught, P.W., van Es, M.A., Blauw, H.M., Fuller, T.F., Langfelder, P., DeYoung, J., Wokke, J.H., Veldink, J.H. et al. (2009) Weighted gene co-expression network analysis of the peripheral blood from Amyotrophic Lateral Sclerosis patients. BMC Genomics, 10, 405.
-
(2009)
BMC Genomics
, vol.10
, pp. 405
-
-
Saris, C.G.1
Horvath, S.2
van Vught, P.W.3
van Es, M.A.4
Blauw, H.M.5
Fuller, T.F.6
Langfelder, P.7
DeYoung, J.8
Wokke, J.H.9
Veldink, J.H.10
-
155
-
-
21644477404
-
Quantitative evidence for neurofilament heavy subunit aggregation in motor neurons of spinal cords of patients with amyotrophic lateral sclerosis
-
Mendonca, D.M., Chimelli, L. and Martinez, A.M. (2005) Quantitative evidence for neurofilament heavy subunit aggregation in motor neurons of spinal cords of patients with amyotrophic lateral sclerosis. Braz. J. Med. Biol. Res., 38, 925-933.
-
(2005)
Braz. J. Med. Biol. Res.
, vol.38
, pp. 925-933
-
-
Mendonca, D.M.1
Chimelli, L.2
Martinez, A.M.3
-
156
-
-
0342657086
-
Motor neurons are rich in non-phosphorylated neurofilaments: cross-species comparison and alterations in ALS
-
Tsang, Y.M., Chiong, F., Kuznetsov, D., Kasarskis, E. and Geula, C. (2000) Motor neurons are rich in non-phosphorylated neurofilaments: cross-species comparison and alterations in ALS. Brain Res., 861, 45-58.
-
(2000)
Brain Res.
, vol.861
, pp. 45-58
-
-
Tsang, Y.M.1
Chiong, F.2
Kuznetsov, D.3
Kasarskis, E.4
Geula, C.5
-
157
-
-
33751243629
-
Neuronal intermediate filaments and ALS: a new look at an old question
-
Xiao, S., McLean, J. and Robertson, J. (2006) Neuronal intermediate filaments and ALS: a new look at an old question. Biochim. Biophys. Acta, 1762, 1001-1012.
-
(2006)
Biochim. Biophys. Acta
, vol.1762
, pp. 1001-1012
-
-
Xiao, S.1
McLean, J.2
Robertson, J.3
-
158
-
-
33746330112
-
The changes of cytoskeletal proteins in plasma of acrylamide-induced rats
-
Yi, C., Xie, K., Song, F., Yu, L., Zhao, X., Li, G. and Yu, S. (2006) The changes of cytoskeletal proteins in plasma of acrylamide-induced rats. Neurochem. Res., 31, 751-757.
-
(2006)
Neurochem. Res.
, vol.31
, pp. 751-757
-
-
Yi, C.1
Xie, K.2
Song, F.3
Yu, L.4
Zhao, X.5
Li, G.6
Yu, S.7
-
159
-
-
51849148493
-
The phosphorylated axonal form of the neurofilament subunit NF-H (pNF-H) as a blood biomarker of traumatic brain injury
-
Anderson, K.J., Scheff, S.W., Miller, K.M., Roberts, K.N., Gilmer, L.K., Yang, C. and Shaw, G. (2008) The phosphorylated axonal form of the neurofilament subunit NF-H (pNF-H) as a blood biomarker of traumatic brain injury. J. Neurotrauma, 25, 1079-1085.
-
(2008)
J. Neurotrauma
, vol.25
, pp. 1079-1085
-
-
Anderson, K.J.1
Scheff, S.W.2
Miller, K.M.3
Roberts, K.N.4
Gilmer, L.K.5
Yang, C.6
Shaw, G.7
-
160
-
-
23144448320
-
Molecular and cellular pathways of neurodegeneration in motor neurone disease
-
Shaw, P.J. (2005) Molecular and cellular pathways of neurodegeneration in motor neurone disease. J. Neurol. Neurosurg. Psychiatry, 76, 1046-1057.
-
(2005)
J. Neurol. Neurosurg. Psychiatry
, vol.76
, pp. 1046-1057
-
-
Shaw, P.J.1
-
161
-
-
59349088328
-
Validation of a novel biomarker for acute axonal injury in experimental autoimmune encephalomyelitis
-
Gresle, M.M., Shaw, G., Jarrott, B., Alexandrou, E.N., Friedhuber, A., Kilpatrick, T.J. and Butzkueven, H. (2008) Validation of a novel biomarker for acute axonal injury in experimental autoimmune encephalomyelitis. J. Neurosci. Res., 86, 3548-3555.
-
(2008)
J. Neurosci. Res.
, vol.86
, pp. 3548-3555
-
-
Gresle, M.M.1
Shaw, G.2
Jarrott, B.3
Alexandrou, E.N.4
Friedhuber, A.5
Kilpatrick, T.J.6
Butzkueven, H.7
-
162
-
-
53749093269
-
Review of the multiple aspects of neurofilament functions, and their possible contribution to neurodegeneration
-
Perrot, R., Berges, R., Bocquet, A. and Eyer, J. (2008) Review of the multiple aspects of neurofilament functions, and their possible contribution to neurodegeneration. Mol. Neurobiol., 38, 27-65.
-
(2008)
Mol. Neurobiol.
, vol.38
, pp. 27-65
-
-
Perrot, R.1
Berges, R.2
Bocquet, A.3
Eyer, J.4
-
163
-
-
33745913017
-
Defective axonal transport of neurofilament proteins in neurons overexpressing peripherin
-
Millecamps, S., Robertson, J., Lariviere, R., Mallet, J. and Julien, J.P. (2006) Defective axonal transport of neurofilament proteins in neurons overexpressing peripherin. J. Neurochem., 98, 926-938.
-
(2006)
J. Neurochem.
, vol.98
, pp. 926-938
-
-
Millecamps, S.1
Robertson, J.2
Lariviere, R.3
Mallet, J.4
Julien, J.P.5
-
164
-
-
79952899321
-
A novel peripherin gene (PRPH) mutation identified in one sporadic amyotrophic lateral sclerosis patient
-
10.1016/j.neurobiolaging.2010.02.011
-
Corrado, L., Carlomagno, Y., Falasco, L., Mellone, S., Godi, M., Cova, E., Cereda, C., Testa, L., Mazzini, L. and D'Alfonso, S. (2010) A novel peripherin gene (PRPH) mutation identified in one sporadic amyotrophic lateral sclerosis patient. Neurobiol. Aging, 10.1016/j.neurobiolaging.2010.02.011.
-
(2010)
Neurobiol. Aging
-
-
Corrado, L.1
Carlomagno, Y.2
Falasco, L.3
Mellone, S.4
Godi, M.5
Cova, E.6
Cereda, C.7
Testa, L.8
Mazzini, L.9
D'Alfonso, S.10
-
165
-
-
4143140690
-
A pathogenic peripherin gene mutation in a patient with amyotrophic lateral sclerosis
-
Leung, C.L., He, C.Z., Kaufmann, P., Chin, S.S., Naini, A., Liem, R.K., Mitsumoto, H. and Hays, A.P. (2004) A pathogenic peripherin gene mutation in a patient with amyotrophic lateral sclerosis. Brain Pathol., 14, 290-296.
-
(2004)
Brain Pathol.
, vol.14
, pp. 290-296
-
-
Leung, C.L.1
He, C.Z.2
Kaufmann, P.3
Chin, S.S.4
Naini, A.5
Liem, R.K.6
Mitsumoto, H.7
Hays, A.P.8
-
166
-
-
39749188127
-
An aggregate-inducing peripherin isoform generated through intron retention is upregulated in amyotrophic lateral sclerosis and associated with disease pathology
-
Xiao, S., Tjostheim, S., Sanelli, T., McLean, J.R., Horne, P., Fan, Y., Ravits, J., Strong, M.J. and Robertson, J. (2008) An aggregate-inducing peripherin isoform generated through intron retention is upregulated in amyotrophic lateral sclerosis and associated with disease pathology. J. Neurosci., 28, 1833-1840.
-
(2008)
J. Neurosci.
, vol.28
, pp. 1833-1840
-
-
Xiao, S.1
Tjostheim, S.2
Sanelli, T.3
McLean, J.R.4
Horne, P.5
Fan, Y.6
Ravits, J.7
Strong, M.J.8
Robertson, J.9
-
167
-
-
0036678094
-
Brain monoglyceride lipase participating in endocannabinoid inactivation
-
Dinh, T.P., Carpenter, D., Leslie, F.M., Freund, T.F., Katona, I., Sensi, S.L., Kathuria, S. and Piomelli, D. (2002) Brain monoglyceride lipase participating in endocannabinoid inactivation. Proc. Natl Acad. Sci. USA, 99, 10819-10824.
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 10819-10824
-
-
Dinh, T.P.1
Carpenter, D.2
Leslie, F.M.3
Freund, T.F.4
Katona, I.5
Sensi, S.L.6
Kathuria, S.7
Piomelli, D.8
-
168
-
-
35648993493
-
Endocannabinoids and neurodegenerative diseases
-
Micale, V., Mazzola, C. and Drago, F. (2007) Endocannabinoids and neurodegenerative diseases. Pharmacol. Res., 56, 382-392.
-
(2007)
Pharmacol. Res.
, vol.56
, pp. 382-392
-
-
Micale, V.1
Mazzola, C.2
Drago, F.3
-
169
-
-
52949103699
-
The endocannabinoid system in amyotrophic lateral sclerosis
-
Bilsland, L.G. and Greensmith, L. (2008) The endocannabinoid system in amyotrophic lateral sclerosis. Curr. Pharm. Des., 14, 2306-2316.
-
(2008)
Curr. Pharm. Des.
, vol.14
, pp. 2306-2316
-
-
Bilsland, L.G.1
Greensmith, L.2
-
170
-
-
41749084838
-
Cannabinoids and neuroprotection in motor-related disorders
-
de Lago, E. and Fernandez-Ruiz, J. (2007) Cannabinoids and neuroprotection in motor-related disorders. CNS Neurol. Disord. Drug Targets, 6, 377-387.
-
(2007)
CNS Neurol. Disord. Drug Targets
, vol.6
, pp. 377-387
-
-
de Lago, E.1
Fernandez-Ruiz, J.2
-
171
-
-
33845683331
-
Increasing cannabinoid levels by pharmacological and genetic manipulation delay disease progression in SOD1 mice
-
Bilsland, L.G., Dick, J.R., Pryce, G., Petrosino, S., Di Marzo, V., Baker, D. and Greensmith, L. (2006) Increasing cannabinoid levels by pharmacological and genetic manipulation delay disease progression in SOD1 mice. FASEB J., 20, 1003-1005.
-
(2006)
FASEB J.
, vol.20
, pp. 1003-1005
-
-
Bilsland, L.G.1
Dick, J.R.2
Pryce, G.3
Petrosino, S.4
Di Marzo, V.5
Baker, D.6
Greensmith, L.7
-
172
-
-
2442484678
-
Amyotrophic lateral sclerosis: delayed disease progression in mice by treatment with a cannabinoid
-
Raman, C., McAllister, S.D., Rizvi, G., Patel, S.G., Moore, D.H. and Abood, M.E. (2004) Amyotrophic lateral sclerosis: delayed disease progression in mice by treatment with a cannabinoid. Amyotroph. Lateral Scler. 5, 33-39.
-
(2004)
Amyotroph. Lateral Scler.
, vol.5
, pp. 33-39
-
-
Raman, C.1
McAllister, S.D.2
Rizvi, G.3
Patel, S.G.4
Moore, D.H.5
Abood, M.E.6
-
173
-
-
26444608731
-
Cannabinol delays symptom onset in SOD1 (G93A) transgenic mice without affecting survival
-
Weydt, P., Hong, S., Witting, A., Moller, T., Stella, N. and Kliot, M. (2005) Cannabinol delays symptom onset in SOD1 (G93A) transgenic mice without affecting survival. Amyotroph. Lateral Scler., 6, 182-184.
-
(2005)
Amyotroph. Lateral Scler.
, vol.6
, pp. 182-184
-
-
Weydt, P.1
Hong, S.2
Witting, A.3
Moller, T.4
Stella, N.5
Kliot, M.6
-
174
-
-
74549185125
-
FAAH and MAGL inhibitors: therapeutic opportunities from regulating endocannabinoid levels
-
Petrosino, S. and Di Marzo, V. (2010) FAAH and MAGL inhibitors: therapeutic opportunities from regulating endocannabinoid levels. Curr. Opin. Investig. Drugs, 11, 51-62.
-
(2010)
Curr. Opin. Investig. Drugs
, vol.11
, pp. 51-62
-
-
Petrosino, S.1
Di Marzo, V.2
-
175
-
-
34848863139
-
Therapeutic potential of endocannabinoid-hydrolysing enzyme inhibitors
-
Saario, S.M. and Laitinen, J.T. (2007) Therapeutic potential of endocannabinoid-hydrolysing enzyme inhibitors. Basic Clin. Pharmacol. Toxicol., 101, 287-293.
-
(2007)
Basic Clin. Pharmacol. Toxicol.
, vol.101
, pp. 287-293
-
-
Saario, S.M.1
Laitinen, J.T.2
-
176
-
-
0023444192
-
Transgenic mice with increased Cu/Zn-superoxide dismutase activity: animal model of dosage effects in Down syndrome
-
Epstein, C.J., Avraham, K.B., Lovett, M., Smith, S., Elroy-Stein, O., Rotman, G., Bry, C. and Groner, Y. (1987) Transgenic mice with increased Cu/Zn-superoxide dismutase activity: animal model of dosage effects in Down syndrome. Proc. Natl Acad. Sci. USA, 84, 8044-8048.
-
(1987)
Proc. Natl Acad. Sci. USA
, vol.84
, pp. 8044-8048
-
-
Epstein, C.J.1
Avraham, K.B.2
Lovett, M.3
Smith, S.4
Elroy-Stein, O.5
Rotman, G.6
Bry, C.7
Groner, Y.8
-
177
-
-
0030499678
-
A vector for expressing foreign genes in the brains and hearts of transgenic mice
-
Borchelt, D.R., Davis, J., Fischer, M., Lee, M.K., Slunt, H.H., Ratovitsky, T., Regard, J., Copeland, N.G., Jenkins, N.A., Sisodia, S.S. et al. (1996) A vector for expressing foreign genes in the brains and hearts of transgenic mice. Genet. Anal., 13, 159-163.
-
(1996)
Genet. Anal.
, vol.13
, pp. 159-163
-
-
Borchelt, D.R.1
Davis, J.2
Fischer, M.3
Lee, M.K.4
Slunt, H.H.5
Ratovitsky, T.6
Regard, J.7
Copeland, N.G.8
Jenkins, N.A.9
Sisodia, S.S.10
-
178
-
-
0032888742
-
Transgenic models of tauopathies and synucleinopathies
-
Trojanowski, J.Q. and Lee, V.M. (1999) Transgenic models of tauopathies and synucleinopathies. Brain Pathol., 9, 733-739.
-
(1999)
Brain Pathol.
, vol.9
, pp. 733-739
-
-
Trojanowski, J.Q.1
Lee, V.M.2
-
179
-
-
0037311919
-
TM4: a free, open-source system for microarray data management and analysis
-
Saeed, A.I., Sharov, V., White, J., Li, J., Liang, W., Bhagabati, N., Braisted, J., Klapa, M., Currier, T., Thiagarajan, M. et al. (2003) TM4: a free, open-source system for microarray data management and analysis. Biotechniques, 34, 374-378.
-
(2003)
Biotechniques
, vol.34
, pp. 374-378
-
-
Saeed, A.I.1
Sharov, V.2
White, J.3
Li, J.4
Liang, W.5
Bhagabati, N.6
Braisted, J.7
Klapa, M.8
Currier, T.9
Thiagarajan, M.10
-
180
-
-
0038005018
-
DAVID: database for annotation, visualization, and integrated discovery
-
Dennis, G. Jr, Sherman, B.T., Hosack, D.A., Yang, J., Gao, W., Lane, H.C. and Lempicki, R.A. (2003) DAVID: database for annotation, visualization, and integrated discovery. Genome Biol., 4,3.
-
(2003)
Genome Biol.
, vol.4
, pp. 3
-
-
Dennis G., Jr.1
Sherman, B.T.2
Hosack, D.A.3
Yang, J.4
Gao, W.5
Lane, H.C.6
Lempicki, R.A.7
-
181
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
Huang da, W., Sherman, B.T. and Lempicki, R.A. (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc., 4, 44-57.
-
(2009)
Nat. Protoc.
, vol.4
, pp. 44-57
-
-
Huang da, W.1
Sherman, B.T.2
Lempicki, R.A.3
-
182
-
-
2942511670
-
PubMatrix: a tool for multiplex literature mining
-
Becker, K.G., Hosack, D.A., Dennis, G. Jr, Lempicki, R.A., Bright, T.J., Cheadle, C. and Engel, J. (2003) PubMatrix: a tool for multiplex literature mining. BMC Bioinformatics, 4, 61.
-
(2003)
BMC Bioinformatics
, vol.4
, pp. 61
-
-
Becker, K.G.1
Hosack, D.A.2
Dennis G., Jr.3
Lempicki, R.A.4
Bright, T.J.5
Cheadle, C.6
Engel, J.7
-
183
-
-
13344278672
-
Content-rich biological network constructed by mining PubMed abstracts
-
Chen, H. and Sharp, B.M. (2004) Content-rich biological network constructed by mining PubMed abstracts. BMC Bioinformatics, 5, 147.
-
(2004)
BMC Bioinformatics
, vol.5
, pp. 147
-
-
Chen, H.1
Sharp, B.M.2
-
184
-
-
33846056843
-
Entrez Gene: gene-centered information at NCBI
-
Maglott, D., Ostell, J., Pruitt, K.D. and Tatusova, T. (2007) Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res., 35, D26-D31.
-
(2007)
Nucleic Acids Res.
, vol.35
-
-
Maglott, D.1
Ostell, J.2
Pruitt, K.D.3
Tatusova, T.4
|