메뉴 건너뛰기




Volumn 20, Issue 7, 2006, Pages

Increasing cannabinoid levels by pharmacological and genetic manipulation delay disease progression in SOD1 mice

Author keywords

Endocannabinoids; Motoneuron; Neurodegeneration; Transgenic mice; WIN55,212 2

Indexed keywords

2 ARACHIDONOYLGLYCEROL; 2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; CANNABINOID; CANNABINOID 1 RECEPTOR; ENDOCANNABINOID; FATTY ACID AMIDASE; AMIDASE; CELL SURFACE RECEPTOR; FATTY-ACID AMIDE HYDROLASE; MORPHOLINE DERIVATIVE; NAPHTHALENE DERIVATIVE; NERVE CELL ADHESION MOLECULE; NEUROPEPTIDE; PCDHA4 PROTEIN, MOUSE; SOD1 G93A PROTEIN; SUPEROXIDE DISMUTASE;

EID: 33845683331     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.05-4743fje     Document Type: Article
Times cited : (134)

References (53)
  • 1
    • 3943102116 scopus 로고    scopus 로고
    • Unraveling the mechanisms involved in motor neuron degeneration in ALS
    • Bruijn, L. I., Miller, T. M., and Cleveland, D. W. (2004) Unraveling the mechanisms involved in motor neuron degeneration in ALS. Annu. Rev. Neurosci. 27, 723-749
    • (2004) Annu. Rev. Neurosci. , vol.27 , pp. 723-749
    • Bruijn, L.I.1    Miller, T.M.2    Cleveland, D.W.3
  • 4
    • 0028097839 scopus 로고
    • A controlled trial of riluzole in amyotrophic lateral sclerosis
    • ALS/Riluzole Study Group
    • Bensimon, G., Lacomblez, L., and Meininger, V. (1994) A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group. N. Engl. J. Med. 330, 585-591
    • (1994) N. Engl. J. Med. , vol.330 , pp. 585-591
    • Bensimon, G.1    Lacomblez, L.2    Meininger, V.3
  • 5
    • 0031706164 scopus 로고    scopus 로고
    • Cannabinoid receptor agonists protect cultured rat hippocampal neurons from excitotoxicity
    • Shen, M. and Thayer, S. A. (1998) Cannabinoid receptor agonists protect cultured rat hippocampal neurons from excitotoxicity. Mol. Pharmacol. 54, 459-462
    • (1998) Mol. Pharmacol. , vol.54 , pp. 459-462
    • Shen, M.1    Thayer, S.A.2
  • 6
    • 0035979606 scopus 로고    scopus 로고
    • Activation of the CB1 cannabinoid receptor protects cultured mouse spinal neurons against excitotoxicity
    • Abood, M. E., Rizvi, G., Sallapudi, N., and McAllister, S. D. (2001) Activation of the CB1 cannabinoid receptor protects cultured mouse spinal neurons against excitotoxicity. Neurosci. Lett. 309, 197-201
    • (2001) Neurosci. Lett. , vol.309 , pp. 197-201
    • Abood, M.E.1    Rizvi, G.2    Sallapudi, N.3    McAllister, S.D.4
  • 9
    • 0033561159 scopus 로고    scopus 로고
    • Cannabinoids and neuroprotection in global and focal cerebral ischemia and in neuronal cultures
    • Nagayama, T., Sinor, A. D., Simon, R. P., Chen, J., Graham, S. H., Jin, K., and Greenberg, D. A. (1999) Cannabinoids and neuroprotection in global and focal cerebral ischemia and in neuronal cultures. J. Neurosci. 19, 2987-2995
    • (1999) J. Neurosci. , vol.19 , pp. 2987-2995
    • Nagayama, T.1    Sinor, A.D.2    Simon, R.P.3    Chen, J.4    Graham, S.H.5    Jin, K.6    Greenberg, D.A.7
  • 10
    • 0030795910 scopus 로고    scopus 로고
    • Anandamide suppresses nitric oxide and TNF-alpha responses to Theiler's virus or endotoxin in astrocytes
    • Molina-Holgado, F., Lledo, A., and Guaza, C. (1997) Anandamide suppresses nitric oxide and TNF-alpha responses to Theiler's virus or endotoxin in astrocytes. Neuroreport 8, 1929-1933
    • (1997) Neuroreport , vol.8 , pp. 1929-1933
    • Molina-Holgado, F.1    Lledo, A.2    Guaza, C.3
  • 11
    • 0033986604 scopus 로고    scopus 로고
    • Cannabinoids inhibit LPS-inducible cytokine mRNA expression in rat microglial cells
    • Puffenbarger, R. A., Boothe, A. C., and Cabral, G. A. (2000) Cannabinoids inhibit LPS-inducible cytokine mRNA expression in rat microglial cells. Glia 29, 58-69
    • (2000) Glia , vol.29 , pp. 58-69
    • Puffenbarger, R.A.1    Boothe, A.C.2    Cabral, G.A.3
  • 13
    • 0038678773 scopus 로고    scopus 로고
    • Reduction of human monocytic cell neurotoxicity and cytokine secretion by ligands of the cannabinoid-type CB2 receptor
    • Klegeris, A., Bissonnette, C. J., and McGeer, P. L. (2003) Reduction of human monocytic cell neurotoxicity and cytokine secretion by ligands of the cannabinoid-type CB2 receptor. Br. J. Pharmacol. 139, 775-786
    • (2003) Br. J. Pharmacol. , vol.139 , pp. 775-786
    • Klegeris, A.1    Bissonnette, C.J.2    McGeer, P.L.3
  • 14
    • 0041842648 scopus 로고    scopus 로고
    • Endogenous interleukin-1 receptor antagonist mediates antiinflammatory and neuroprotective actions of cannabinoids in neurons and glia
    • Molina-Holgado, F., Pinteaux, E., Moore, J. D., Molina-Holgado, E., Guaza, C., Gibson, R. M., and Rothwell, N. J. (2003) Endogenous interleukin-1 receptor antagonist mediates antiinflammatory and neuroprotective actions of cannabinoids in neurons and glia. J. Neurosci. 23, 6470-6474
    • (2003) J. Neurosci. , vol.23 , pp. 6470-6474
    • Molina-Holgado, F.1    Pinteaux, E.2    Moore, J.D.3    Molina-Holgado, E.4    Guaza, C.5    Gibson, R.M.6    Rothwell, N.J.7
  • 17
    • 0029889256 scopus 로고    scopus 로고
    • Biosynthesis of an endogenous cannabinoid precursor in neurons and its control by calcium and cAMP
    • Cadas, H., Gaillet, S., Beltramo, M., Venance, L., and Piomelli, D. (1996) Biosynthesis of an endogenous cannabinoid precursor in neurons and its control by calcium and cAMP. J. Neurosci. 16, 3934-3942
    • (1996) J. Neurosci. , vol.16 , pp. 3934-3942
    • Cadas, H.1    Gaillet, S.2    Beltramo, M.3    Venance, L.4    Piomelli, D.5
  • 18
    • 0034685625 scopus 로고    scopus 로고
    • Generation of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, in picrotoxinin-administered rat brain
    • Sugiura, T., Yoshinaga, N., Kondo, S., Waku, K., and Ishima, Y. (2000) Generation of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, in picrotoxinin-administered rat brain. Biochem. Biophys. Res. Commun. 271, 654-658
    • (2000) Biochem. Biophys. Res. Commun. , vol.271 , pp. 654-658
    • Sugiura, T.1    Yoshinaga, N.2    Kondo, S.3    Waku, K.4    Ishima, Y.5
  • 23
    • 0033769188 scopus 로고    scopus 로고
    • Levels, metabolism, and pharmacological activity of anandamide in CB(1) cannabinoid receptor knockout mice: Evidence for non-CB(1), non-CB(2) receptor-mediated actions of anandamide in mouse brain
    • Di Marzo., V, Breivogel, C. S., Tao, Q., Bridgen, D. T., Razdan, R. K., Zimmer, A. M., Zimmer, A., and Martin, B. R. (2000) Levels, metabolism, and pharmacological activity of anandamide in CB(1) cannabinoid receptor knockout mice: evidence for non-CB(1), non-CB(2) receptor-mediated actions of anandamide in mouse brain. J. Neurochem. 75, 2434-2444
    • (2000) J. Neurochem. , vol.75 , pp. 2434-2444
    • Di Marzo, V.1    Breivogel, C.S.2    Tao, Q.3    Bridgen, D.T.4    Razdan, R.K.5    Zimmer, A.M.6    Zimmer, A.7    Martin, B.R.8
  • 24
    • 1842504064 scopus 로고    scopus 로고
    • Inhibition of calpains, by treatment with leupeptin, improves motoneuron survival and muscle function in models of motoneuron degeneration
    • Kieran, D. and Greensmith, L. (2004) Inhibition of calpains, by treatment with leupeptin, improves motoneuron survival and muscle function in models of motoneuron degeneration. Neuroscience 125, 427-439
    • (2004) Neuroscience , vol.125 , pp. 427-439
    • Kieran, D.1    Greensmith, L.2
  • 26
    • 3042559925 scopus 로고    scopus 로고
    • Endocannabinoids accumulate in spinal cord of SOD1 transgenic mice
    • Witting, A., Weydt, P., Hong, S., Kliot, M., Moller, T., and Stella, N. (2004) Endocannabinoids accumulate in spinal cord of SOD1 transgenic mice. J. Neurochem. 89, 1555-1557
    • (2004) J. Neurochem. , vol.89 , pp. 1555-1557
    • Witting, A.1    Weydt, P.2    Hong, S.3    Kliot, M.4    Moller, T.5    Stella, N.6
  • 27
    • 11844267193 scopus 로고    scopus 로고
    • The effect of peripheral nerve injury on disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis
    • Sharp, P. S., Dick, J. R., and Greensmith, L. (2005) The effect of peripheral nerve injury on disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis. Neuroscience 130, 897-910
    • (2005) Neuroscience , vol.130 , pp. 897-910
    • Sharp, P.S.1    Dick, J.R.2    Greensmith, L.3
  • 29
    • 0037986558 scopus 로고    scopus 로고
    • The AMPA receptor antagonist NBQX prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis
    • Van Damme, P., Leyssen, M., Callewaert, G., Robberecht, W., and Van den Bosch. L. (2003) The AMPA receptor antagonist NBQX prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis. Neurosci. Lett. 343, 81-84
    • (2003) Neurosci. Lett. , vol.343 , pp. 81-84
    • Van Damme, P.1    Leyssen, M.2    Callewaert, G.3    Robberecht, W.4    Van Den Bosch, L.5
  • 30
    • 1842611884 scopus 로고    scopus 로고
    • Cannabinoids and neuroinflammation
    • Walter, L. and Stella, N. (2004) Cannabinoids and neuroinflammation. Br. J. Pharmacol. 141, 775-785
    • (2004) Br. J. Pharmacol. , vol.141 , pp. 775-785
    • Walter, L.1    Stella, N.2
  • 31
    • 0032493197 scopus 로고    scopus 로고
    • Cannabidiol and (-)Delta9-tetrahydrocannabinol are neuroprotective antioxidants
    • Hampson, A. J., Grimaldi, M., Axelrod, J., and Wink, D. (1998) Cannabidiol and (-)Delta9-tetrahydrocannabinol are neuroprotective antioxidants. Proc. Natl. Acad. Sci. USA 95, 8268-8273
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 8268-8273
    • Hampson, A.J.1    Grimaldi, M.2    Axelrod, J.3    Wink, D.4
  • 32
    • 0036488182 scopus 로고    scopus 로고
    • Neuroprotective properties of cannabinoids against oxidative stress: Role of the cannabinoid receptor CB1
    • Marsicano, G., Moosmann, B., Hermann, H., Lutz, B., and Behl, C. (2002) Neuroprotective properties of cannabinoids against oxidative stress: role of the cannabinoid receptor CB1. J. Neurochem. 80, 448-456
    • (2002) J. Neurochem. , vol.80 , pp. 448-456
    • Marsicano, G.1    Moosmann, B.2    Hermann, H.3    Lutz, B.4    Behl, C.5
  • 33
    • 0025954862 scopus 로고
    • Characterization and localization of cannabinoid receptors in rat brain: A quantitative in vitro autoradiographic study
    • Herkenham, M., Lynn, A. B., Johnson, M. R., Melvin, L. S., de Costa, B. R., and Rice, K. C. (1991) Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic study. J. Neurosci. 11, 563-583
    • (1991) J. Neurosci. , vol.11 , pp. 563-583
    • Herkenham, M.1    Lynn, A.B.2    Johnson, M.R.3    Melvin, L.S.4    De Costa, B.R.5    Rice, K.C.6
  • 36
    • 0036317952 scopus 로고    scopus 로고
    • Blockade of cannabinoid CB(1) receptor function protects against in vivo disseminating brain damage following NMDA-induced excitotoxicity
    • Hansen, H. H., Azcoitia, I., Pons, S., Romero, J., Garcia-Segura, L. M., Ramos, J. A., Hansen, H. S., and Fernandez-Ruiz, J. (2002) Blockade of cannabinoid CB(1) receptor function protects against in vivo disseminating brain damage following NMDA-induced excitotoxicity. J. Neurochem. 82, 154-158
    • (2002) J. Neurochem. , vol.82 , pp. 154-158
    • Hansen, H.H.1    Azcoitia, I.2    Pons, S.3    Romero, J.4    Garcia-Segura, L.M.5    Ramos, J.A.6    Hansen, H.S.7    Fernandez-Ruiz, J.8
  • 38
    • 0037440415 scopus 로고    scopus 로고
    • Cannabinoids ablate release of TNFalpha in rat microglial cells stimulated with lypopolysaccharide
    • Facchinetti, F., Del Giudice, E., Furegato, S., Passarotto, M., and Leon, A. (2003) Cannabinoids ablate release of TNFalpha in rat microglial cells stimulated with lypopolysaccharide. Glia 41, 161-168
    • (2003) Glia , vol.41 , pp. 161-168
    • Facchinetti, F.1    Del Giudice, E.2    Furegato, S.3    Passarotto, M.4    Leon, A.5
  • 39
    • 0036787810 scopus 로고    scopus 로고
    • Inflammatory processes in amyotrophic lateral sclerosis
    • McGeer, P. L. and McGeer, E. G. (2002) Inflammatory processes in amyotrophic lateral sclerosis. Muscle Nerve 26, 459-470
    • (2002) Muscle Nerve , vol.26 , pp. 459-470
    • McGeer, P.L.1    McGeer, E.G.2
  • 40
    • 0035949799 scopus 로고    scopus 로고
    • Marked increase in cyclooxygenase-2 in ALS spinal cord: Implications for therapy
    • Yasojima, K., Tourtellotte, W. W., McGeer, E. G., and McGeer, P. L. (2001) Marked increase in cyclooxygenase-2 in ALS spinal cord: implications for therapy. Neurology 57, 952-956
    • (2001) Neurology , vol.57 , pp. 952-956
    • Yasojima, K.1    Tourtellotte, W.W.2    McGeer, E.G.3    McGeer, P.L.4
  • 41
    • 0141816705 scopus 로고    scopus 로고
    • Expression and localization of cyclooxygenase-1 and -2 in human sporadic amyotrophic lateral sclerosis
    • Maihofner, C., Probst-Cousin, S., Bergmann, M., Neuhuber, W., Neundorfer, B., and Heuss, D. (2003) Expression and localization of cyclooxygenase-1 and -2 in human sporadic amyotrophic lateral sclerosis. Eur. J. Neurosci. 18, 1527-1534
    • (2003) Eur. J. Neurosci. , vol.18 , pp. 1527-1534
    • Maihofner, C.1    Probst-Cousin, S.2    Bergmann, M.3    Neuhuber, W.4    Neundorfer, B.5    Heuss, D.6
  • 42
    • 0032125587 scopus 로고    scopus 로고
    • Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS
    • Hall, E. D., Oostveen, J. A., and Gurney, M. E. (1998) Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS. Glia 23, 249-256
    • (1998) Glia , vol.23 , pp. 249-256
    • Hall, E.D.1    Oostveen, J.A.2    Gurney, M.E.3
  • 43
    • 0035833937 scopus 로고    scopus 로고
    • Immune reactivity in a mouse model of familial ALS correlates with disease progression
    • Alexianu, M. E., Kozovska, M., and Appel, S. H. (2001) Immune reactivity in a mouse model of familial ALS correlates with disease progression. Neurology 57, 1282-1289
    • (2001) Neurology , vol.57 , pp. 1282-1289
    • Alexianu, M.E.1    Kozovska, M.2    Appel, S.H.3
  • 45
    • 17144462251 scopus 로고    scopus 로고
    • Therapeutic action of cannabinoids in a murine model of multiple sclerosis
    • Arevalo-Martin, A., Vela, J. M., Molina-Holgado, E., Borrell, J., and Guaza, C. (2003) Therapeutic action of cannabinoids in a murine model of multiple sclerosis. J. Neurosci. 23, 2511-2516
    • (2003) J. Neurosci. , vol.23 , pp. 2511-2516
    • Arevalo-Martin, A.1    Vela, J.M.2    Molina-Holgado, E.3    Borrell, J.4    Guaza, C.5
  • 46
    • 0036209082 scopus 로고    scopus 로고
    • Minocycline prevents neurotoxicity induced by cerebrospinal fluid from patients with motor neurone disease
    • Tikka, T. M., Vartiainen, N. E., Goldsteins, G., Oja, S. S., Andersen, P. M., Marklund, S. L., and Koistinaho, J. (2002) Minocycline prevents neurotoxicity induced by cerebrospinal fluid from patients with motor neurone disease. Brain 125, 722-731
    • (2002) Brain , vol.125 , pp. 722-731
    • Tikka, T.M.1    Vartiainen, N.E.2    Goldsteins, G.3    Oja, S.S.4    Andersen, P.M.5    Marklund, S.L.6    Koistinaho, J.7
  • 47
    • 0037389393 scopus 로고    scopus 로고
    • A therapeutic role for cyclooxygenase-2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis
    • Pompl, P. N., Ho, L., Bianchi, M., McManus, T., Qin, W., and Pasinetti, G. M. (2003) A therapeutic role for cyclooxygenase-2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis. FASEB J. 17, 725-727
    • (2003) FASEB J. , vol.17 , pp. 725-727
    • Pompl, P.N.1    Ho, L.2    Bianchi, M.3    McManus, T.4    Qin, W.5    Pasinetti, G.M.6
  • 48
  • 50
    • 0035801320 scopus 로고    scopus 로고
    • Novel cannabinoid-sensitive receptor mediates inhibition of glutamatergic synaptic transmission in the hippocampus
    • Hajos, N., Ledent, C., and Freund, T. F. (2001) Novel cannabinoid-sensitive receptor mediates inhibition of glutamatergic synaptic transmission in the hippocampus. Neuroscience 106, 1-4
    • (2001) Neuroscience , vol.106 , pp. 1-4
    • Hajos, N.1    Ledent, C.2    Freund, T.F.3
  • 53
    • 1942486792 scopus 로고    scopus 로고
    • Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice
    • Kieran, D., Kalmar, B., Dick, J. R., Riddoch-Contreras, J., Burnstock, G., and Greensmith, L. (2004) Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice. Nat. Med. 10, 402-405
    • (2004) Nat. Med. , vol.10 , pp. 402-405
    • Kieran, D.1    Kalmar, B.2    Dick, J.R.3    Riddoch-Contreras, J.4    Burnstock, G.5    Greensmith, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.