메뉴 건너뛰기




Volumn 189, Issue 7, 2010, Pages 1059-1070

Clearance of apoptotic cells: Implications in health and disease

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALPHAVBETA5 INTEGRIN; COMPLEMENT COMPONENT C1Q; DEOXYRIBONUCLEASE II; DNA; DOCK180 PROTEIN; ELMO PROTEIN; FRACTALKINE; GROWTH ARREST SPECIFIC PROTEIN 6; GULP1 PROTEIN; LACTADHERIN; LOW DENSITY LIPOPROTEIN; LXR ALPHA PROTEIN; LXR BETA PROTEIN; LYSOPHOSPHATIDYLCHOLINE; MEGF10 PROTEIN; MER PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PROTEIN; RAC PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; TIM 4 PROTEIN; TOLL LIKE RECEPTOR; UNCLASSIFIED DRUG; URIDINE TRIPHOSPHATE; VITRONECTIN RECEPTOR;

EID: 77954396042     PISSN: 00219525     EISSN: 00219525     Source Type: Journal    
DOI: 10.1083/jcb.201004096     Document Type: Review
Times cited : (424)

References (154)
  • 1
    • 68949145931 scopus 로고    scopus 로고
    • Apoptotic cells promote their own clearance and immune tolerance through activation of the nuclear receptor LXR
    • doi:10.1016/j.immuni.2009.06.018
    • A-Gonzalez, N., S.J. Bensinger, C. Hong, S. Beceiro, M.N. Bradley, N. Zelcer, J. Deniz, C. Ramirez, M. Díaz, G. Gallardo, et al. 2009. Apoptotic cells promote their own clearance and immune tolerance through activation of the nuclear receptor LXR. Immunity. 31:245-258. doi:10.1016/j.immuni.2009.06.018
    • (2009) Immunity , vol.31 , pp. 245-258
    • A-Gonzalez, N.1    Bensinger, S.J.2    Hong, C.3    Beceiro, S.4    Bradley, M.N.5    Zelcer, N.6    Deniz, J.7    Ramirez, C.8    Díaz, M.9    Gallardo, G.10
  • 4
    • 0033625871 scopus 로고    scopus 로고
    • Alphavbeta5 integrin recruits the CrkII-Dock180-rac1 complex for phagocytosis of apoptotic cells
    • doi:10.1038/35046549
    • Albert, M.L., J.I. Kim, and R.B. Birge. 2000. alphavbeta5 integrin recruits the CrkII-Dock180-rac1 complex for phagocytosis of apoptotic cells. Nat. Cell Biol. 2:899-905. doi:10.1038/35046549
    • (2000) Nat. Cell Biol. , vol.2 , pp. 899-905
    • Albert, M.L.1    Kim, J.I.2    Birge, R.B.3
  • 5
    • 4344715014 scopus 로고    scopus 로고
    • Masking of phosphatidylserine inhibits apoptotic cell engulfment and induces autoantibody production in mice
    • doi:10.1084/jem.20040342
    • Asano, K., M. Miwa, K. Miwa, R. Hanayama, H. Nagase, S. Nagata, and M. Tanaka. 2004. Masking of phosphatidylserine inhibits apoptotic cell engulfment and induces autoantibody production in mice. J. Exp. Med. 200:459-467. doi:10.1084/jem.20040342
    • (2004) J. Exp. Med. , vol.200 , pp. 459-467
    • Asano, K.1    Miwa, M.2    Miwa, K.3    Hanayama, R.4    Nagase, H.5    Nagata, S.6    Tanaka, M.7
  • 6
    • 76249128304 scopus 로고    scopus 로고
    • Tumor cell death and ATP release prime dendritic cells and efficient anticancer immunity
    • doi:10.1158/0008-5472.CAN-09-3566
    • Aymeric, L., L. Apetoh, F. Ghiringhelli, A. Tesniere, I. Martins, G. Kroemer, M.J. Smyth, and L. Zitvogel. 2010. Tumor cell death and ATP release prime dendritic cells and efficient anticancer immunity. Cancer Res. 70:855-858. doi:10.1158/0008-5472.CAN-09-3566
    • (2010) Cancer Res. , vol.70 , pp. 855-858
    • Aymeric, L.1    Apetoh, L.2    Ghiringhelli, F.3    Tesniere, A.4    Martins, I.5    Kroemer, G.6    Smyth, M.J.7    Zitvogel, L.8
  • 7
    • 62949116803 scopus 로고    scopus 로고
    • Lysosomal disorders: From storage to cellular damage
    • doi:10.1016/j.bbamcr.2008.12.001
    • Ballabio, A., and V. Gieselmann. 2009. Lysosomal disorders: from storage to cellular damage. Biochim. Biophys. Acta. 1793:684-696. doi:10.1016/j.bbamcr. 2008.12.001
    • (2009) Biochim. Biophys. Acta. , vol.1793 , pp. 684-696
    • Ballabio, A.1    Gieselmann, V.2
  • 8
    • 33847033030 scopus 로고    scopus 로고
    • Complement C1q reduces early atherosclerosis in low-density lipoprotein receptor-deficient mice
    • doi:10.2353/ajpath.2007.060406
    • Bhatia, V.K., S. Yun, V. Leung, D.C. Grimsditch, G.M. Benson, M.B. Botto, J.J. Boyle, and D.O. Haskard. 2007. Complement C1q reduces early atherosclerosis in low-density lipoprotein receptor-deficient mice. Am. J. Pathol. 170:416-426. doi:10.2353/ajpath.2007.060406
    • (2007) Am. J. Pathol. , vol.170 , pp. 416-426
    • Bhatia, V.K.1    Yun, S.2    Leung, V.3    Grimsditch, D.C.4    Benson, G.M.5    Botto, M.B.6    Boyle, J.J.7    Haskard, D.O.8
  • 11
    • 77950461862 scopus 로고    scopus 로고
    • Vesicular traffic: A Rab SANDwich
    • doi:10.1016/j.cub.2010.02.030
    • Bohdanowicz, M., and S. Grinstein. 2010. Vesicular traffic: a Rab SANDwich. Curr. Biol. 20:R311-R314. doi:10.1016/j.cub.2010.02.030
    • (2010) Curr. Biol. , vol.20
    • Bohdanowicz, M.1    Grinstein, S.2
  • 16
    • 0037062989 scopus 로고    scopus 로고
    • Apoptosis disables CD31-mediated cell detachment from phagocytes promoting binding and engulfment
    • DOI 10.1038/nature00811
    • Brown, S., I. Heinisch, E. Ross, K. Shaw, C.D. Buckley, and J. Savill. 2002. Apoptosis disables CD31-mediated cell detachment from phagocytes promoting binding and engulfment. Nature. 418:200-203. doi:10.1038/nature00811 (Pubitemid 34773776)
    • (2002) Nature , vol.418 , Issue.6894 , pp. 200-203
    • Brown, S.1    Heinisch, I.2    Ross, E.3    Shaw, K.4    Buckley, C.O.5    Savill, J.6
  • 19
    • 0034231922 scopus 로고    scopus 로고
    • Phosphatidylserine-dependent phagocytosis of apoptotic glioma cells by normal human microglia, astrocytes, and glioma cells
    • doi:10.1215/15228517-2-3-174
    • Chang, G.H., N.M. Barbaro, and R.O. Pieper. 2000. Phosphatidylserine- dependent phagocytosis of apoptotic glioma cells by normal human microglia, astrocytes, and glioma cells. Neuro-oncol. 2:174-183. doi:10.1215/15228517-2-3- 174
    • (2000) Neuro-oncol. , vol.2 , pp. 174-183
    • Chang, G.H.1    Barbaro, N.M.2    Pieper, R.O.3
  • 21
    • 37049031230 scopus 로고    scopus 로고
    • Interleukin-10 expression in macrophages during phagocytosis of apoptotic cells is mediated by homeodomain proteins Pbx1 and Prep-1
    • doi:10.1016/j.immuni.2007.11.014
    • Chung, E.Y., J. Liu, Y. Homma, Y. Zhang, A. Brendolan, M. Saggese, J. Han, R. Silverstein, L. Selleri, and X. Ma. 2007. Interleukin-10 expression in macrophages during phagocytosis of apoptotic cells is mediated by homeodomain proteins Pbx1 and Prep-1. Immunity. 27:952-964. doi:10.1016/j.immuni.2007.11.014
    • (2007) Immunity , vol.27 , pp. 952-964
    • Chung, E.Y.1    Liu, J.2    Homma, Y.3    Zhang, Y.4    Brendolan, A.5    Saggese, M.6    Han, J.7    Silverstein, R.8    Selleri, L.9    Ma, X.10
  • 23
    • 0037465557 scopus 로고    scopus 로고
    • Decreased atherosclerotic lesion formation in CX3CR1/apolipoprotein e double knockout mice
    • DOI 10.1161/01.CIR.0000057548.68243.42
    • Combadière, C., S. Potteaux, J.L. Gao, B. Esposito, S. Casanova, E.J. Lee, P. Debré, A. Tedgui, P.M. Murphy, and Z. Mallat. 2003. Decreased atherosclerotic lesion formation in CX3CR1/apolipoprotein E double knockout mice. Circulation. 107:1009-1016. doi:10.1161/01.CIR.0000057548.68243. 42 (Pubitemid 36258725)
    • (2003) Circulation , vol.107 , Issue.7 , pp. 1009-1016
    • Combadiere, C.1    Potteaux, S.2    Gao, J.-L.3    Esposito, B.4    Casanova, S.5    Lee, E.J.6    Debre, P.7    Tedgui, A.8    Murphy, P.M.9    Mallat, Z.10
  • 24
    • 31044433663 scopus 로고    scopus 로고
    • Macrophages: Obligate partners for tumor cell migration, invasion, and metastasis
    • DOI 10.1016/j.cell.2006.01.007, PII S0092867406000559
    • Condeelis, J., and J.W. Pollard. 2006. Macrophages: obligate partners for tumor cell migration, invasion, and metastasis. Cell. 124:263-266. doi:10.1016/j.cell.2006.01.007 (Pubitemid 43121975)
    • (2006) Cell , vol.124 , Issue.2 , pp. 263-266
    • Condeelis, J.1    Pollard, J.W.2
  • 25
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • doi:10.1038/nature01322
    • Coussens, L.M., and Z. Werb. 2002. Inflammation and cancer. Nature. 420:860-867. doi:10.1038/nature01322
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 26
    • 1642536490 scopus 로고    scopus 로고
    • Innate Immune Discrimination of Apoptotic Cells: Repression of Proinflammatory Macrophage Transcription is Coupled Directly to Specific Recognition
    • Cvetanovic, M., and D.S. Ucker. 2004. Innate immune discrimination of apoptotic cells: repression of proinflammatory macrophage transcription is coupled directly to specific recognition. J. Immunol. 172:880-889. (Pubitemid 38113745)
    • (2004) Journal of Immunology , vol.172 , Issue.2 , pp. 880-889
    • Cvetanovic, M.1    Ucker, D.S.2
  • 28
    • 19944376460 scopus 로고    scopus 로고
    • Phagocytosis of apoptotic cells is regulated by a UNC-73/TRIO-MIG-2/RhoG signaling module and armadillo repeats of CED-12/ELMO
    • doi:10.1016/j.cub.2004.12.029
    • deBakker, C.D., L.B. Haney, J.M. Kinchen, C. Grimsley, M. Lu, D. Klingele, P.K. Hsu, B.K. Chou, L.C. Cheng, A. Blangy, et al. 2004. Phagocytosis of apoptotic cells is regulated by a UNC-73/TRIO-MIG-2/RhoG signaling module and armadillo repeats of CED-12/ELMO. Curr. Biol. 14:2208-2216. doi:10.1016/j.cub.2004.12.029
    • (2004) Curr. Biol. , vol.14 , pp. 2208-2216
    • DeBakker, C.D.1    Haney, L.B.2    Kinchen, J.M.3    Grimsley, C.4    Lu, M.5    Klingele, D.6    Hsu, P.K.7    Chou, B.K.8    Cheng, L.C.9    Blangy, A.10
  • 29
    • 0037959621 scopus 로고    scopus 로고
    • CD14-dependent clearance of apoptotic cells by human macrophages: The role of phosphatidylserine
    • DOI 10.1038/sj.cdd.4401168
    • Devitt, A., S. Pierce, C. Oldreive, W.H. Shingler, and C.D. Gregory. 2003. CD14-dependent clearance of apoptotic cells by human macrophages: the role of phosphatidylserine. Cell Death Differ. 10:371-382. doi:10.1038/sj.cdd. 4401168 (Pubitemid 36582375)
    • (2003) Cell Death and Differentiation , vol.10 , Issue.3 , pp. 371-382
    • Devitt, A.1    Pierce, S.2    Oldreive, C.3    Shingler, W.H.4    Gregory, C.D.5
  • 31
    • 34547656330 scopus 로고    scopus 로고
    • Immunological consequences of apoptotic cell phagocytosis
    • doi:10.2353/ajpath.2007.070135
    • Erwig, L.P., and P.M. Henson. 2007. Immunological consequences of apoptotic cell phagocytosis. Am. J. Pathol. 171:2-8. doi:10.2353/ajpath.2007. 070135
    • (2007) Am. J. Pathol. , vol.171 , pp. 2-8
    • Erwig, L.P.1    Henson, P.M.2
  • 32
    • 38049123476 scopus 로고    scopus 로고
    • Clearance of apoptotic cells by phagocytes
    • doi:10.1038/sj.cdd.4402184
    • Erwig, L.P., and P.M. Henson. 2008. Clearance of apoptotic cells by phagocytes. Cell Death Differ. 15:243-250. doi:10.1038/sj.cdd.4402184
    • (2008) Cell Death Differ. , vol.15 , pp. 243-250
    • Erwig, L.P.1    Henson, P.M.2
  • 33
    • 33748084030 scopus 로고    scopus 로고
    • Differential regulation of phagosome maturation in macrophages and dendritic cells mediated by Rho GTPases and ezrinradixin-moesin (ERM) proteins
    • doi:10.1073/pnas.0605331103
    • Erwig, L.P., K.A. McPhilips, M.W. Wynes, A. Ivetic, A.J. Ridley, and P.M. Henson. 2006. Differential regulation of phagosome maturation in macrophages and dendritic cells mediated by Rho GTPases and ezrinradixin-moesin (ERM) proteins. Proc. Natl. Acad. Sci. USA. 103:12825-12830. doi:10.1073/pnas. 0605331103
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 12825-12830
    • Erwig, L.P.1    McPhilips, K.A.2    Wynes, M.W.3    Ivetic, A.4    Ridley, A.J.5    Henson, P.M.6
  • 34
    • 0026508561 scopus 로고
    • Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages
    • Fadok, V.A., D.R. Voelker, P.A. Campbell, J.J. Cohen, D.L. Bratton, and P.M. Henson. 1992. Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J. Immunol. 148:2207-2216.
    • (1992) J. Immunol. , vol.148 , pp. 2207-2216
    • Fadok, V.A.1    Voelker, D.R.2    Campbell, P.A.3    Cohen, J.J.4    Bratton, D.L.5    Henson, P.M.6
  • 35
    • 0032519925 scopus 로고    scopus 로고
    • Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF
    • doi:10.1172/JCI1112
    • Fadok, V.A., D.L. Bratton, A. Konowal, P.W. Freed, J.Y. Westcott, and P.M. Henson. 1998. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. J. Clin. Invest. 101:890-898. doi:10.1172/JCI1112
    • (1998) J. Clin. Invest. , vol.101 , pp. 890-898
    • Fadok, V.A.1    Bratton, D.L.2    Konowal, A.3    Freed, P.W.4    Westcott, J.Y.5    Henson, P.M.6
  • 36
    • 0346216136 scopus 로고    scopus 로고
    • Expression of stabilin-2, a novel fasciclin-like hyaluronan receptor protein, in murine sinusoidal endothelia, avascular tissues, and at solid/liquid interfaces
    • doi:10.1007/s00418-003-0585-5
    • Falkowski, M., K. Schledzewski, B. Hansen, and S. Goerdt. 2003. Expression of stabilin-2, a novel fasciclin-like hyaluronan receptor protein, in murine sinusoidal endothelia, avascular tissues, and at solid/liquid interfaces. Histochem. Cell Biol. 120:361-369. doi:10.1007/s00418-003-0585-5
    • (2003) Histochem. Cell Biol. , vol.120 , pp. 361-369
    • Falkowski, M.1    Schledzewski, K.2    Hansen, B.3    Goerdt, S.4
  • 37
    • 0025277242 scopus 로고
    • CD14 is a member of the family of leucine-rich proteins and is encoded by a gene syntenic with multiple receptor genes
    • Ferrero, E., C.L. Hsieh, U. Francke, and S.M. Goyert. 1990. CD14 is a member of the family of leucine-rich proteins and is encoded by a gene syntenic with multiple receptor genes. J. Immunol. 145:331-336. (Pubitemid 20217420)
    • (1990) Journal of Immunology , vol.145 , Issue.1 , pp. 331-336
    • Ferrero, E.1    Hsieh, C.-L.2    Francke, U.3    Goyert, S.M.4
  • 38
    • 3242766671 scopus 로고    scopus 로고
    • Absence of C1q leads to less neuropathology in transgenic mouse models of Alzheimer's disease
    • doi:10.1523/JNEUROSCI.0901-04.2004
    • Fonseca, M.I., J. Zhou, M. Botto, and A.J. Tenner. 2004. Absence of C1q leads to less neuropathology in transgenic mouse models of Alzheimer's disease. J. Neurosci. 24:6457-6465. doi:10.1523/JNEUROSCI.0901-04.2004
    • (2004) J. Neurosci. , vol.24 , pp. 6457-6465
    • Fonseca, M.I.1    Zhou, J.2    Botto, M.3    Tenner, A.J.4
  • 39
    • 55849085357 scopus 로고    scopus 로고
    • MFG-E8 regulates microglial phagocytosis of apoptotic neurons
    • doi:10.1007/s11481-008-9118-2
    • Fuller, A.D., and L.J. Van Eldik. 2008. MFG-E8 regulates microglial phagocytosis of apoptotic neurons. J. Neuroimmune Pharmacol. 3:246-256. doi:10.1007/s11481-008-9118-2
    • (2008) J. Neuroimmune Pharmacol. , vol.3 , pp. 246-256
    • Fuller, A.D.1    Van Eldik, L.J.2
  • 40
  • 41
    • 0033757463 scopus 로고    scopus 로고
    • Mutations in MERTK, the human orthologue of the RCS rat retinal dystrophy gene, cause retinitis pigmentosa
    • doi:10.1038/80002
    • Gal, A., Y. Li, D.A. Thompson, J. Weir, U. Orth, S.G. Jacobson, E. Apfelstedt-Sylla, and D. Vollrath. 2000. Mutations in MERTK, the human orthologue of the RCS rat retinal dystrophy gene, cause retinitis pigmentosa. Nat. Genet. 26:270-271. doi:10.1038/80002
    • (2000) Nat. Genet. , vol.26 , pp. 270-271
    • Gal, A.1    Li, Y.2    Thompson, D.A.3    Weir, J.4    Orth, U.5    Jacobson, S.G.6    Apfelstedt-Sylla, E.7    Vollrath, D.8
  • 43
    • 33747463996 scopus 로고    scopus 로고
    • Microglia biology in health and disease
    • doi:10.1007/s11481-006-9015-5
    • Garden, G.A., and T. Möller. 2006. Microglia biology in health and disease. J. Neuroimmune Pharmacol. 1:127-137. doi:10.1007/s11481-006-9015-5
    • (2006) J. Neuroimmune Pharmacol. , vol.1 , pp. 127-137
    • Garden, G.A.1    Möller, T.2
  • 44
    • 33644746231 scopus 로고    scopus 로고
    • TNFalpha induces ABCA1 through NF-kappaB in macrophages and in phagocytes ingesting apoptotic cells
    • doi:10.1073/pnas.0510345103
    • Gerbod-Giannone, M.C., Y. Li, A. Holleboom, S. Han, L.C. Hsu, I. Tabas, and A.R. Tall. 2006. TNFalpha induces ABCA1 through NF-kappaB in macrophages and in phagocytes ingesting apoptotic cells. Proc. Natl. Acad. Sci. USA. 103:3112-3117. doi:10.1073/pnas.0510345103
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 3112-3117
    • Gerbod-Giannone, M.C.1    Li, Y.2    Holleboom, A.3    Han, S.4    Hsu, L.C.5    Tabas, I.6    Tall, A.R.7
  • 45
  • 49
    • 2442665179 scopus 로고    scopus 로고
    • Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice
    • DOI 10.1126/science.1094359
    • Hanayama, R., M. Tanaka, K. Miyasaka, K. Aozasa, M. Koike, Y. Uchiyama, and S. Nagata. 2004. Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice. Science. 304:1147-1150. doi:10.1126/science.1094359 (Pubitemid 38661849)
    • (2004) Science , vol.304 , Issue.5674 , pp. 1147-1150
    • Hanayama, R.1    Tanaka, M.2    Miyasaka, K.3    Aozasa, K.4    Koike, M.5    Uchiyama, Y.6    Nagata, S.7
  • 53
    • 72549108621 scopus 로고    scopus 로고
    • Antiphosphatidylserine antibody combined with irradiation damages tumor blood vessels and induces tumor immunity in a rat model of glioblastoma
    • doi:10.1158/1078-0432.CCR-09-1499
    • He, J., Y. Yin, T.A. Luster, L. Watkins, and P.E. Thorpe. 2009. Antiphosphatidylserine antibody combined with irradiation damages tumor blood vessels and induces tumor immunity in a rat model of glioblastoma. Clin. Cancer Res. 15:6871-6880. doi:10.1158/1078-0432.CCR-09-1499
    • (2009) Clin. Cancer Res. , vol.15 , pp. 6871-6880
    • He, J.1    Yin, Y.2    Luster, T.A.3    Watkins, L.4    Thorpe, P.E.5
  • 54
    • 42049111834 scopus 로고    scopus 로고
    • Apoptosis in the lung: Induction, clearance and detection
    • doi:10.1152/ajplung.00320.2007
    • Henson, P.M., and R.M. Tuder. 2008. Apoptosis in the lung: induction, clearance and detection. Am. J. Physiol. Lung Cell. Mol. Physiol. 294:L601-L611. doi:10.1152/ajplung.00320.2007
    • (2008) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.294
    • Henson, P.M.1    Tuder, R.M.2
  • 55
    • 0041346077 scopus 로고    scopus 로고
    • Alveolar macrophages from subjects with chronic obstructive pulmonary disease are deficient in their ability to phagocytose apoptotic airway epithelial cells
    • doi:10.1046/j.1440-1711.2003.t01-1-01170.x
    • Hodge, S., G. Hodge, R. Scicchitano, P.N. Reynolds, and M. Holmes. 2003. Alveolar macrophages from subjects with chronic obstructive pulmonary disease are deficient in their ability to phagocytose apoptotic airway epithelial cells. Immunol. Cell Biol. 81:289-296. doi:10.1046/j.1440-1711.2003.t01-1-01170.x
    • (2003) Immunol. Cell Biol. , vol.81 , pp. 289-296
    • Hodge, S.1    Hodge, G.2    Scicchitano, R.3    Reynolds, P.N.4    Holmes, M.5
  • 56
    • 14744295733 scopus 로고    scopus 로고
    • Increased airway epithelial and T-cell apoptosis in COPD remains despite smoking cessation
    • doi:10.1183/09031936.05.00077604
    • Hodge, S., G. Hodge, M. Holmes, and P.N. Reynolds. 2005. Increased airway epithelial and T-cell apoptosis in COPD remains despite smoking cessation. Eur. Respir. J. 25:447-454. doi:10.1183/09031936.05.00077604
    • (2005) Eur. Respir. J. , vol.25 , pp. 447-454
    • Hodge, S.1    Hodge, G.2    Holmes, M.3    Reynolds, P.N.4
  • 57
    • 36749021632 scopus 로고    scopus 로고
    • Smoking alters alveolar macrophage recognition and phagocytic ability: Implications in chronic obstructive pulmonary disease
    • doi:10.1165/rcmb.2007-0025OC
    • Hodge, S., G. Hodge, J. Ahern, H. Jersmann, M. Holmes, and P.N. Reynolds. 2007. Smoking alters alveolar macrophage recognition and phagocytic ability: implications in chronic obstructive pulmonary disease. Am. J. Respir. Cell Mol. Biol. 37:748-755. doi:10.1165/rcmb.2007-0025OC
    • (2007) Am. J. Respir. Cell Mol. Biol. , vol.37 , pp. 748-755
    • Hodge, S.1    Hodge, G.2    Ahern, J.3    Jersmann, H.4    Holmes, M.5    Reynolds, P.N.6
  • 58
    • 46849097573 scopus 로고    scopus 로고
    • Azithromycin improves macrophage phagocytic function and expression of mannose receptor in chronic obstructive pulmonary disease
    • doi:10.1164/rccm.200711-1666OC
    • Hodge, S., G. Hodge, H. Jersmann, G. Matthews, J. Ahern, M. Holmes, and P.N. Reynolds. 2008. Azithromycin improves macrophage phagocytic function and expression of mannose receptor in chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 178:139-148. doi:10.1164/rccm.200711-1666OC
    • (2008) Am. J. Respir. Crit. Care Med. , vol.178 , pp. 139-148
    • Hodge, S.1    Hodge, G.2    Jersmann, H.3    Matthews, G.4    Ahern, J.5    Holmes, M.6    Reynolds, P.N.7
  • 59
    • 56249140398 scopus 로고    scopus 로고
    • Coordination of inflammation and metabolism by PPAR and LXR nuclear receptors
    • doi:10.1016/j.gde.2008.07.016
    • Hong, C., and P. Tontonoz. 2008. Coordination of inflammation and metabolism by PPAR and LXR nuclear receptors. Curr. Opin. Genet. Dev. 18:461-467. doi:10.1016/j.gde.2008.07.016
    • (2008) Curr. Opin. Genet. Dev. , vol.18 , pp. 461-467
    • Hong, C.1    Tontonoz, P.2
  • 60
    • 20144374032 scopus 로고    scopus 로고
    • A monoclonal antibody that binds anionic phospholipids on tumor blood vessels enhances the antitumor effect of docetaxel on human breast tumors in mice
    • DOI 10.1158/0008-5472.CAN-05-0031
    • Huang, X., M. Bennett, and P.E. Thorpe. 2005. A monoclonal antibody that binds anionic phospholipids on tumor blood vessels enhances the antitumor effect of docetaxel on human breast tumors in mice. Cancer Res. 65:4408-4416. doi:10.1158/0008-5472.CAN-05-0031 (Pubitemid 40775680)
    • (2005) Cancer Research , vol.65 , Issue.10 , pp. 4408-4416
    • Huang, X.1    Bennett, M.2    Thorpe, P.E.3
  • 61
    • 26944476623 scopus 로고    scopus 로고
    • Defective apoptotic cell phagocytosis attenuates prostaglandin E2 and 15-hydroxyeicosatetraenoic acid in severe asthma alveolar macrophages
    • doi:10.1164/rccm.200501-035OC
    • Huynh, M.L., K.C. Malcolm, C. Kotaru, J.A. Tilstra, J.Y. Westcott, V.A. Fadok, and S.E. Wenzel. 2005. Defective apoptotic cell phagocytosis attenuates prostaglandin E2 and 15-hydroxyeicosatetraenoic acid in severe asthma alveolar macrophages. Am. J. Respir. Crit. Care Med. 172:972-979. doi:10.1164/rccm. 200501-035OC
    • (2005) Am. J. Respir. Crit. Care Med. , vol.172 , pp. 972-979
    • Huynh, M.L.1    Malcolm, K.C.2    Kotaru, C.3    Tilstra, J.A.4    Westcott, J.Y.5    Fadok, V.A.6    Wenzel, S.E.7
  • 62
    • 19344363916 scopus 로고    scopus 로고
    • HIV-1 Nef binds the DOCK2-ELMO1 complex to activate rac and inhibit lymphocyte chemotaxis
    • doi:10.1371/journal.pbio.0020006
    • Janardhan, A., T. Swigut, B. Hill, M.P. Myers, and J. Skowronski. 2004. HIV-1 Nef binds the DOCK2-ELMO1 complex to activate rac and inhibit lymphocyte chemotaxis. PLoS Biol. 2:E6. doi:10.1371/journal.pbio.0020006
    • (2004) PLoS Biol. , vol.2
    • Janardhan, A.1    Swigut, T.2    Hill, B.3    Myers, M.P.4    Skowronski, J.5
  • 63
    • 34547616112 scopus 로고    scopus 로고
    • ELMO1 and Dock180, a bipartite Rac1 guanine nucleotide exchange factor, promote human glioma cell invasion
    • doi:10.1158/0008-5472.CAN-07-0473
    • Jarzynka, M.J., B. Hu, K.M. Hui, I. Bar-Joseph, W. Gu, T. Hirose, L.B. Haney, K.S. Ravichandran, R. Nishikawa, and S.Y. Cheng. 2007. ELMO1 and Dock180, a bipartite Rac1 guanine nucleotide exchange factor, promote human glioma cell invasion. Cancer Res. 67:7203-7211. doi:10.1158/0008-5472.CAN-07-0473
    • (2007) Cancer Res. , vol.67 , pp. 7203-7211
    • Jarzynka, M.J.1    Hu, B.2    Hui, K.M.3    Bar-Joseph, I.4    Gu, W.5    Hirose, T.6    Haney, L.B.7    Ravichandran, K.S.8    Nishikawa, R.9    Cheng, S.Y.10
  • 64
    • 55349147987 scopus 로고    scopus 로고
    • Milk fat globule EGF-8 promotes melanoma progression through coordinated Akt and twist signaling in the tumor microenvironment
    • doi:10.1158/0008-5472.CAN-08-2147
    • Jinushi, M., Y. Nakazaki, D.R. Carrasco, D. Draganov, N. Souders, M. Johnson, M.C. Mihm, and G. Dranoff. 2008. Milk fat globule EGF-8 promotes melanoma progression through coordinated Akt and twist signaling in the tumor microenvironment. Cancer Res. 68:8889-8898. doi:10.1158/0008-5472.CAN-08-2147
    • (2008) Cancer Res. , vol.68 , pp. 8889-8898
    • Jinushi, M.1    Nakazaki, Y.2    Carrasco, D.R.3    Draganov, D.4    Souders, N.5    Johnson, M.6    Mihm, M.C.7    Dranoff, G.8
  • 65
    • 67449147143 scopus 로고    scopus 로고
    • Milk fat globule epidermal growth factor-8 blockade triggers tumor destruction through coordinated cell-autonomous and immune-mediated mechanisms
    • doi:10.1084/jem.20082614
    • Jinushi, M., M. Sato, A. Kanamoto, A. Itoh, S. Nagai, S. Koyasu, G. Dranoff, and H. Tahara. 2009. Milk fat globule epidermal growth factor-8 blockade triggers tumor destruction through coordinated cell-autonomous and immune-mediated mechanisms. J. Exp. Med. 206:1317-1326. doi:10.1084/jem.20082614
    • (2009) J. Exp. Med. , vol.206 , pp. 1317-1326
    • Jinushi, M.1    Sato, M.2    Kanamoto, A.3    Itoh, A.4    Nagai, S.5    Koyasu, S.6    Dranoff, G.7    Tahara, H.8
  • 66
    • 0042674398 scopus 로고    scopus 로고
    • RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo
    • doi:10.1038/nature01817
    • Katoh, H., and M. Negishi. 2003. RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo. Nature. 424:461-464. doi:10.1038/nature01817
    • (2003) Nature , vol.424 , pp. 461-464
    • Katoh, H.1    Negishi, M.2
  • 69
    • 3242689804 scopus 로고    scopus 로고
    • Milestones of neuronal development in the adult hippocampus
    • doi:10.1016/j.tins.2004.05.013
    • Kempermann, G., S. Jessberger, B. Steiner, and G. Kronenberg. 2004. Milestones of neuronal development in the adult hippocampus. Trends Neurosci. 27:447-452. doi:10.1016/j.tins.2004.05.013
    • (2004) Trends Neurosci. , vol.27 , pp. 447-452
    • Kempermann, G.1    Jessberger, S.2    Steiner, B.3    Kronenberg, G.4
  • 70
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr, J.F., A.H. Wyllie, and A.R. Currie. 1972. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer. 26:239-257.
    • (1972) Br. J. Cancer. , vol.26 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 71
    • 77956938316 scopus 로고    scopus 로고
    • A model to die for: Signaling to apoptotic cell removal in worm, fly and mouse
    • In press
    • Kinchen, J.M. 2010. A model to die for: signaling to apoptotic cell removal in worm, fly and mouse. Apoptosis. In press.
    • (2010) Apoptosis
    • Kinchen, J.M.1
  • 72
    • 77950460749 scopus 로고    scopus 로고
    • Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells
    • doi:10.1038/nature08853
    • Kinchen, J.M., and K.S. Ravichandran. 2010. Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells. Nature. 464:778-782. doi:10.1038/nature08853
    • (2010) Nature , vol.464 , pp. 778-782
    • Kinchen, J.M.1    Ravichandran, K.S.2
  • 74
    • 1942504217 scopus 로고    scopus 로고
    • Macrophage phagocytosis of apoptotic neutrophils is compromised by matrix proteins modified by cigarette smoke and lipid peroxidation products
    • doi:10.1016/j.bbrc.2004.04.003
    • Kirkham, P.A., G. Spooner, I. Rahman, and A.G. Rossi. 2004. Macrophage phagocytosis of apoptotic neutrophils is compromised by matrix proteins modified by cigarette smoke and lipid peroxidation products. Biochem. Biophys. Res. Commun. 318:32-37. doi:10.1016/j.bbrc.2004.04.003
    • (2004) Biochem. Biophys. Res. Commun. , vol.318 , pp. 32-37
    • Kirkham, P.A.1    Spooner, G.2    Rahman, I.3    Rossi, A.G.4
  • 75
    • 33750957975 scopus 로고    scopus 로고
    • Apoptotic cells induce a phosphatidylserine-dependent homeostatic response from phagocytes
    • doi:10.1016/j.cub.2006.09.043
    • Kiss, R.S., M.R. Elliott, Z. Ma, Y.L. Marcel, and K.S. Ravichandran. 2006a. Apoptotic cells induce a phosphatidylserine-dependent homeostatic response from phagocytes. Curr. Biol. 16:2252-2258. doi:10.1016/j.cub.2006.09. 043
    • (2006) Curr. Biol. , vol.16 , pp. 2252-2258
    • Kiss, R.S.1    Elliott, M.R.2    Ma, Z.3    Marcel, Y.L.4    Ravichandran, K.S.5
  • 76
    • 33744952845 scopus 로고    scopus 로고
    • The lipoprotein receptor-related protein-1 (LRP) adapter protein GULP mediates trafficking of the LRP ligand prosaposin, leading to sphingolipid and free cholesterol accumulation in late endosomes and impaired efflux
    • doi:10.1074/jbc.M600621200
    • Kiss, R.S., Z. Ma, K. Nakada-Tsukui, E. Brugnera, G. Vassiliou, H.M. McBride, K.S. Ravichandran, and Y.L. Marcel. 2006b. The lipoprotein receptor-related protein-1 (LRP) adapter protein GULP mediates trafficking of the LRP ligand prosaposin, leading to sphingolipid and free cholesterol accumulation in late endosomes and impaired efflux. J. Biol. Chem. 281:12081-12092. doi:10.1074/jbc.M600621200
    • (2006) J. Biol. Chem. , vol.281 , pp. 12081-12092
    • Kiss, R.S.1    Ma, Z.2    Nakada-Tsukui, K.3    Brugnera, E.4    Vassiliou, G.5    McBride, H.M.6    Ravichandran, K.S.7    Marcel, Y.L.8
  • 79
    • 0345358534 scopus 로고    scopus 로고
    • Statinmediated correction of STAT1 signaling and inducible nitric oxide synthase expression in cystic fibrosis epithelial cells
    • Kreiselmeier, N.E., N.C. Kraynack, D.A. Corey, and T.J. Kelley. 2003. Statinmediated correction of STAT1 signaling and inducible nitric oxide synthase expression in cystic fibrosis epithelial cells. Am. J. Physiol. Lung Cell. Mol. Physiol. 285:L1286-L1295.
    • (2003) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.285
    • Kreiselmeier, N.E.1    Kraynack, N.C.2    Corey, D.A.3    Kelley, T.J.4
  • 80
    • 0036707510 scopus 로고    scopus 로고
    • Deoxyribonuclease IIalpha is required during the phagocytic phase of apoptosis and its loss causes perinatal lethality
    • doi:10.1038/sj.cdd.4401056
    • Krieser, R.J., K.S. MacLea, D.S. Longnecker, J.L. Fields, S. Fiering, and A. Eastman. 2002. Deoxyribonuclease IIalpha is required during the phagocytic phase of apoptosis and its loss causes perinatal lethality. Cell Death Differ. 9:956-962. doi:10.1038/sj.cdd.4401056
    • (2002) Cell Death Differ. , vol.9 , pp. 956-962
    • Krieser, R.J.1    MacLea, K.S.2    Longnecker, D.S.3    Fields, J.L.4    Fiering, S.5    Eastman, A.6
  • 82
    • 0038820117 scopus 로고    scopus 로고
    • Apoptotic cells induce migration of phagocytes via caspase-3-mediated release of a lipid attraction signal
    • doi:10.1016/S0092-8674(03)00422-7
    • Lauber, K., E. Bohn, S.M. Kröber, Y.J. Xiao, S.G. Blumenthal, R.K. Lindemann, P. Marini, C. Wiedig, A. Zobywalski, S. Baksh, et al. 2003. Apoptotic cells induce migration of phagocytes via caspase-3-mediated release of a lipid attraction signal. Cell. 113:717-730. doi:10.1016/S0092-8674(03)00422-7
    • (2003) Cell , vol.113 , pp. 717-730
    • Lauber, K.1    Bohn, E.2    Kröber, S.M.3    Xiao, Y.J.4    Blumenthal, S.G.5    Lindemann, R.K.6    Marini, P.7    Wiedig, C.8    Zobywalski, A.9    Baksh, S.10
  • 83
    • 2342584674 scopus 로고    scopus 로고
    • Clearance of apoptotic cells: Getting rid of the corpses
    • doi:10.1016/S1097-2765(04)00237-0
    • Lauber, K., S.G. Blumenthal, M. Waibel, and S. Wesselborg. 2004. Clearance of apoptotic cells: getting rid of the corpses. Mol. Cell. 14:277-287. doi:10.1016/S1097-2765(04)00237-0
    • (2004) Mol. Cell. , vol.14 , pp. 277-287
    • Lauber, K.1    Blumenthal, S.G.2    Waibel, M.3    Wesselborg, S.4
  • 84
    • 0035020493 scopus 로고    scopus 로고
    • Mice lacking the orphan G proteincoupled receptor G2A develop a late-onset autoimmune syndrome
    • doi:10.1016/S1074-7613(01)00145-5
    • Le, L.Q., J.H. Kabarowski, Z. Weng, A.B. Satterthwaite, E.T. Harvill, E.R. Jensen, J.F. Miller, and O.N. Witte. 2001. Mice lacking the orphan G proteincoupled receptor G2A develop a late-onset autoimmune syndrome. Immunity. 14:561-571. doi:10.1016/S1074-7613(01)00145-5
    • (2001) Immunity , vol.14 , pp. 561-571
    • Le, L.Q.1    Kabarowski, J.H.2    Weng, Z.3    Satterthwaite, A.B.4    Harvill, E.T.5    Jensen, E.R.6    Miller, J.F.7    Witte, O.N.8
  • 86
    • 0035128074 scopus 로고    scopus 로고
    • Requirement for Rho GTPases and PI 3-kinases during apoptotic cell phagocytosis by macrophages
    • doi:10.1016/S0960-9822(01)00047-1
    • Leverrier, Y., and A.J. Ridley. 2001. Requirement for Rho GTPases and PI 3-kinases during apoptotic cell phagocytosis by macrophages. Curr. Biol. 11:195-199. doi:10.1016/S0960-9822(01)00047-1
    • (2001) Curr. Biol. , vol.11 , pp. 195-199
    • Leverrier, Y.1    Ridley, A.J.2
  • 87
    • 46449103344 scopus 로고    scopus 로고
    • TAM receptor tyrosine kinases: Biologic functions, signaling, and potential therapeutic targeting in human cancer
    • doi:10.1016/S0065-230X(08)00002-X
    • Linger, R.M., A.K. Keating, H.S. Earp, and D.K. Graham. 2008. TAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer. Adv. Cancer Res. 100:35-83. doi:10.1016/S0065-230X(08)00002-X
    • (2008) Adv. Cancer Res. , vol.100 , pp. 35-83
    • Linger, R.M.1    Keating, A.K.2    Earp, H.S.3    Graham, D.K.4
  • 89
    • 0037317032 scopus 로고    scopus 로고
    • Transglutaminases: Crosslinking enzymes with pleiotropic functions
    • doi:10.1038/nrm1014
    • Lorand, L., and R.M. Graham. 2003. Transglutaminases: crosslinking enzymes with pleiotropic functions. Nat. Rev. Mol. Cell Biol. 4:140-156. doi:10.1038/nrm1014
    • (2003) Nat. Rev. Mol. Cell Biol. , vol.4 , pp. 140-156
    • Lorand, L.1    Graham, R.M.2
  • 91
    • 0036715053 scopus 로고    scopus 로고
    • Astrocytes are less efficient in the removal of apoptotic lymphocytes than microglia cells: Implications for the role of glial cells in the inflamed central nervous system
    • Magnus, T., A. Chan, R.A. Linker, K.V. Toyka, and R. Gold. 2002. Astrocytes are less efficient in the removal of apoptotic lymphocytes than microglia cells: implications for the role of glial cells in the inflamed central nervous system. J. Neuropathol. Exp. Neurol. 61:760-766.
    • (2002) J. Neuropathol. Exp. Neurol. , vol.61 , pp. 760-766
    • Magnus, T.1    Chan, A.2    Linker, R.A.3    Toyka, K.V.4    Gold, R.5
  • 93
    • 34548064499 scopus 로고    scopus 로고
    • Interactions of bacterial effector proteins with host proteins
    • doi:10.1016/j.coi.2007.06.005
    • Mattoo, S., Y.M. Lee, and J.E. Dixon. 2007. Interactions of bacterial effector proteins with host proteins. Curr. Opin. Immunol. 19:392-401. doi:10.1016/j.coi.2007.06.005
    • (2007) Curr. Opin. Immunol. , vol.19 , pp. 392-401
    • Mattoo, S.1    Lee, Y.M.2    Dixon, J.E.3
  • 94
    • 0033485401 scopus 로고    scopus 로고
    • Transcriptional and translational regulation of inflammatory mediator production by endogenous TGF-beta in macrophages that have ingested apoptotic cells
    • McDonald, P.P., V.A. Fadok, D. Bratton, and P.M. Henson. 1999. Transcriptional and translational regulation of inflammatory mediator production by endogenous TGF-beta in macrophages that have ingested apoptotic cells. J. Immunol. 163:6164-6172.
    • (1999) J. Immunol. , vol.163 , pp. 6164-6172
    • McDonald, P.P.1    Fadok, V.A.2    Bratton, D.3    Henson, P.M.4
  • 95
    • 0031825552 scopus 로고    scopus 로고
    • Systemic exposure to irradiated apoptotic cells induces autoantibody production
    • doi:10.1084/jem.188.2.387
    • Mevorach, D., J.L. Zhou, X. Song, and K.B. Elkon. 1998. Systemic exposure to irradiated apoptotic cells induces autoantibody production. J. Exp. Med. 188:387-392. doi:10.1084/jem.188.2.387
    • (1998) J. Exp. Med. , vol.188 , pp. 387-392
    • Mevorach, D.1    Zhou, J.L.2    Song, X.3    Elkon, K.B.4
  • 96
    • 36248944555 scopus 로고    scopus 로고
    • Identification of Tim4 as a phosphatidylserine receptor
    • doi:10.1038/nature06307
    • Miyanishi, M., K. Tada, M. Koike, Y. Uchiyama, T. Kitamura, and S. Nagata. 2007. Identification of Tim4 as a phosphatidylserine receptor. Nature. 450:435-439. doi:10.1038/nature06307
    • (2007) Nature , vol.450 , pp. 435-439
    • Miyanishi, M.1    Tada, K.2    Koike, M.3    Uchiyama, Y.4    Kitamura, T.5    Nagata, S.6
  • 97
    • 0029942337 scopus 로고    scopus 로고
    • Histochemical detection of apoptosis in Parkinson's disease
    • doi:10.1016/0022-510X(95)00336-Z
    • Mochizuki, H., K. Goto, H. Mori, and Y. Mizuno. 1996. Histochemical detection of apoptosis in Parkinson's disease. J. Neurol. Sci. 137:120-123. doi:10.1016/0022-510X(95)00336-Z
    • (1996) J. Neurol. Sci. , vol.137 , pp. 120-123
    • Mochizuki, H.1    Goto, K.2    Mori, H.3    Mizuno, Y.4
  • 99
    • 54549102284 scopus 로고    scopus 로고
    • Derailed endocytosis: An emerging feature of cancer
    • doi:10.1038/nrc2521
    • Mosesson, Y., G.B. Mills, and Y. Yarden. 2008. Derailed endocytosis: an emerging feature of cancer. Nat. Rev. Cancer. 8:835-850. doi:10.1038/nrc2521
    • (2008) Nat. Rev. Cancer. , vol.8 , pp. 835-850
    • Mosesson, Y.1    Mills, G.B.2    Yarden, Y.3
  • 101
    • 77949914141 scopus 로고    scopus 로고
    • Scent of dying cells: The role of attraction signals in the clearance of apoptotic cells and its immunological consequences
    • doi:10.1016/j.autrev.2009.11.016
    • Muñoz, L.E., C. Peter, M. Herrmann, S. Wesselborg, and K. Lauber. 2010. Scent of dying cells: the role of attraction signals in the clearance of apoptotic cells and its immunological consequences. Autoimmun. Rev. 9:425-430. doi:10.1016/j.autrev.2009.11.016
    • (2010) Autoimmun. Rev. , vol.9 , pp. 425-430
    • Muñoz, L.E.1    Peter, C.2    Herrmann, M.3    Wesselborg, S.4    Lauber, K.5
  • 102
    • 77649152255 scopus 로고    scopus 로고
    • Autoimmunity and the clearance of dead cells
    • doi:10.1016/j.cell.2010.02.014
    • Nagata, S., R. Hanayama, and K. Kawane. 2010. Autoimmunity and the clearance of dead cells. Cell. 140:619-630. doi:10.1016/j.cell.2010.02.014
    • (2010) Cell , vol.140 , pp. 619-630
    • Nagata, S.1    Hanayama, R.2    Kawane, K.3
  • 103
    • 33646828766 scopus 로고    scopus 로고
    • Opposite effects of rho family GTPases on engulfment of apoptotic cells by macrophages
    • doi:10.1074/jbc.M510972200
    • Nakaya, M., M. Tanaka, Y. Okabe, R. Hanayama, and S. Nagata. 2006. Opposite effects of rho family GTPases on engulfment of apoptotic cells by macrophages. J. Biol. Chem. 281:8836-8842. doi:10.1074/jbc.M510972200
    • (2006) J. Biol. Chem. , vol.281 , pp. 8836-8842
    • Nakaya, M.1    Tanaka, M.2    Okabe, Y.3    Hanayama, R.4    Nagata, S.5
  • 104
    • 65549168745 scopus 로고    scopus 로고
    • Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation
    • doi:10.1182/blood-2008-10-185884
    • Nakayama, M., H. Akiba, K. Takeda, Y. Kojima, M. Hashiguchi, M. Azuma, H. Yagita, and K. Okumura. 2009. Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation. Blood. 113:3821-3830. doi:10.1182/blood-2008-10-185884
    • (2009) Blood , vol.113 , pp. 3821-3830
    • Nakayama, M.1    Akiba, H.2    Takeda, K.3    Kojima, Y.4    Hashiguchi, M.5    Azuma, M.6    Yagita, H.7    Okumura, K.8
  • 105
    • 34547531848 scopus 로고    scopus 로고
    • Essential role for MFG-E8 as ligand for alphavbeta5 integrin in diurnal retinal phagocytosis
    • doi:10.1073/pnas.0704756104
    • Nandrot, E.F., M. Anand, D. Almeida, K. Atabai, D. Sheppard, and S.C. Finnemann. 2007. Essential role for MFG-E8 as ligand for alphavbeta5 integrin in diurnal retinal phagocytosis. Proc. Natl. Acad. Sci. USA. 104:12005-12010. doi:10.1073/pnas.0704756104
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 12005-12010
    • Nandrot, E.F.1    Anand, M.2    Almeida, D.3    Atabai, K.4    Sheppard, D.5    Finnemann, S.C.6
  • 106
    • 0034114882 scopus 로고    scopus 로고
    • Features of systemic lupus erythematosus in Dnase1-deficient mice
    • doi:10.1038/76032
    • Napirei, M., H. Karsunky, B. Zevnik, H. Stephan, H.G. Mannherz, and T. Möröy. 2000. Features of systemic lupus erythematosus in Dnase1-deficient mice. Nat. Genet. 25:177-181. doi:10.1038/76032
    • (2000) Nat. Genet. , vol.25 , pp. 177-181
    • Napirei, M.1    Karsunky, H.2    Zevnik, B.3    Stephan, H.4    Mannherz, H.G.5    Möröy, T.6
  • 107
    • 14044259331 scopus 로고    scopus 로고
    • Enhanced apoptotic cell clearance capacity and B cell survival factor production by IL-10-activated macrophages: Implications for Burkitt's lymphoma
    • Ogden, C.A., J.D. Pound, B.K. Batth, S. Owens, I. Johannessen, K. Wood, and C.D. Gregory. 2005. Enhanced apoptotic cell clearance capacity and B cell survival factor production by IL-10-activated macrophages: implications for Burkitt's lymphoma. J. Immunol. 174:3015-3023.
    • (2005) J. Immunol. , vol.174 , pp. 3015-3023
    • Ogden, C.A.1    Pound, J.D.2    Batth, B.K.3    Owens, S.4    Johannessen, I.5    Wood, K.6    Gregory, C.D.7
  • 108
    • 36248987290 scopus 로고    scopus 로고
    • BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module
    • DOI 10.1038/nature06329, PII NATURE06329
    • Park, D., A.C. Tosello-Trampont, M.R. Elliott, M. Lu, L.B. Haney, Z. Ma, A.L. Klibanov, J.W. Mandell, and K.S. Ravichandran. 2007. BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module. Nature. 450:430-434. doi:10.1038/nature06329 (Pubitemid 350126756)
    • (2007) Nature , vol.450 , Issue.7168 , pp. 430-434
    • Park, D.1    Tosello-Trampont, A.-C.2    Elliott, M.R.3    Lu, M.4    Haney, L.B.5    Ma, Z.6    Klibanov, A.L.7    Mandell, J.W.8    Ravichandran, K.S.9
  • 109
  • 110
    • 60349123136 scopus 로고    scopus 로고
    • The phosphatidylserine receptor TIM-4 does not mediate direct signaling
    • doi:10.1016/j.cub.2009.01.042
    • Park, D., A. Hochreiter-Hufford, and K.S. Ravichandran. 2009. The phosphatidylserine receptor TIM-4 does not mediate direct signaling. Curr. Biol. 19:346-351. doi:10.1016/j.cub.2009.01.042
    • (2009) Curr. Biol. , vol.19 , pp. 346-351
    • Park, D.1    Hochreiter-Hufford, A.2    Ravichandran, K.S.3
  • 111
    • 0034644114 scopus 로고    scopus 로고
    • Differences between the clearance of apoptotic cells by professional and non-professional phagocytes
    • doi:10.1016/S0960-9822(00)00598-4
    • Parnaik, R., M.C. Raff, and J. Scholes. 2000. Differences between the clearance of apoptotic cells by professional and non-professional phagocytes. Curr. Biol. 10:857-860. doi:10.1016/S0960-9822(00)00598-4
    • (2000) Curr. Biol. , vol.10 , pp. 857-860
    • Parnaik, R.1    Raff, M.C.2    Scholes, J.3
  • 112
    • 70350536554 scopus 로고    scopus 로고
    • Confirmation of genetic associations at ELMO1 in the GoKinD collection supports its role as a susceptibility gene in diabetic nephropathy
    • doi:10.2337/db09-0641
    • Pezzolesi, M.G., P. Katavetin, M. Kure, G.D. Poznik, J. Skupien, J.C. Mychaleckyj, S.S. Rich, J.H. Warram, and A.S. Krolewski. 2009a. Confirmation of genetic associations at ELMO1 in the GoKinD collection supports its role as a susceptibility gene in diabetic nephropathy. Diabetes. 58:2698-2702. doi:10.2337/db09-0641
    • (2009) Diabetes , vol.58 , pp. 2698-2702
    • Pezzolesi, M.G.1    Katavetin, P.2    Kure, M.3    Poznik, G.D.4    Skupien, J.5    Mychaleckyj, J.C.6    Rich, S.S.7    Warram, J.H.8    Krolewski, A.S.9
  • 114
    • 41849142292 scopus 로고    scopus 로고
    • Comparison of the expression profile of apoptosis-associated genes in rheumatoid arthritis and osteoarthritis
    • doi:10.1007/s00296-008-0534-7
    • Qingchun, H., H. Runyue, J. LiGang, C. Yongliang, W. Song, and Z. Shujing. 2008. Comparison of the expression profile of apoptosis-associated genes in rheumatoid arthritis and osteoarthritis. Rheumatol. Int. 28:697-701. doi:10.1007/s00296-008-0534-7
    • (2008) Rheumatol. Int. , vol.28 , pp. 697-701
    • Qingchun, H.1    Runyue, H.2    LiGang, J.3    Yongliang, C.4    Song, W.5    Shujing, Z.6
  • 115
    • 14644430393 scopus 로고    scopus 로고
    • Antitumor effects of a monoclonal antibody that binds anionic phospholipids on the surface of tumor blood vessels in mice
    • doi:10.1158/1078-0432.CCR-04-1645
    • Ran, S., J. He, X. Huang, M. Soares, D. Scothorn, and P.E. Thorpe. 2005. Antitumor effects of a monoclonal antibody that binds anionic phospholipids on the surface of tumor blood vessels in mice. Clin. Cancer Res. 11:1551-1562. doi:10.1158/1078-0432.CCR-04-1645
    • (2005) Clin. Cancer Res. , vol.11 , pp. 1551-1562
    • Ran, S.1    He, J.2    Huang, X.3    Soares, M.4    Scothorn, D.5    Thorpe, P.E.6
  • 116
    • 36448961645 scopus 로고    scopus 로고
    • Engulfment of apoptotic cells: Signals for a good meal
    • doi:10.1038/nri2214
    • Ravichandran, K.S., and U. Lorenz. 2007. Engulfment of apoptotic cells: signals for a good meal. Nat. Rev. Immunol. 7:964-974. doi:10.1038/nri2214
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 964-974
    • Ravichandran, K.S.1    Lorenz, U.2
  • 117
    • 8444252166 scopus 로고    scopus 로고
    • The engulfment process of programmed cell death in caenorhabditis elegans
    • doi:10.1146/annurev.cellbio.20.022003.114619
    • Reddien, P.W., and H.R. Horvitz. 2004. The engulfment process of programmed cell death in caenorhabditis elegans. Annu. Rev. Cell Dev. Biol. 20:193-221. doi:10.1146/annurev.cellbio.20.022003.114619
    • (2004) Annu. Rev. Cell Dev. Biol. , vol.20 , pp. 193-221
    • Reddien, P.W.1    Horvitz, H.R.2
  • 118
    • 0142072318 scopus 로고    scopus 로고
    • Increased Apoptotic Neutrophils and Macrophages and Impaired Macrophage Phagocytic Clearance of Apoptotic Neutrophils in Systemic Lupus Erythematosus
    • DOI 10.1002/art.11237
    • Ren, Y., J. Tang, M.Y. Mok, A.W. Chan, A. Wu, and C.S. Lau. 2003. Increased apoptotic neutrophils and macrophages and impaired macrophage phagocytic clearance of apoptotic neutrophils in systemic lupus erythematosus. Arthritis Rheum. 48:2888-2897. doi:10.1002/art.11237 (Pubitemid 37280618)
    • (2003) Arthritis and Rheumatism , vol.48 , Issue.10 , pp. 2888-2897
    • Ren, Y.1    Tang, J.2    Mok, M.Y.3    Chan, A.W.K.4    Wu, A.5    Lau, C.S.6
  • 120
  • 121
    • 66149150664 scopus 로고    scopus 로고
    • Yersinia enterocolitica differentially modulates RhoG activity in host cells
    • doi:10.1242/jcs.040345
    • Roppenser, B., A. Röder, M. Hentschke, K. Ruckdeschel, and M. Aepfelbacher. 2009. Yersinia enterocolitica differentially modulates RhoG activity in host cells. J. Cell Sci. 122:696-705. doi:10.1242/jcs.040345
    • (2009) J. Cell Sci. , vol.122 , pp. 696-705
    • Roppenser, B.1    Röder, A.2    Hentschke, M.3    Ruckdeschel, K.4    Aepfelbacher, M.5
  • 122
    • 0025164935 scopus 로고
    • Vitronectin receptor-mediated phagocytosis of cells undergoing apoptosis
    • doi:10.1038/343170a0
    • Savill, J., I. Dransfield, N. Hogg, and C. Haslett. 1990. Vitronectin receptor-mediated phagocytosis of cells undergoing apoptosis. Nature. 343:170-173. doi:10.1038/343170a0
    • (1990) Nature , vol.343 , pp. 170-173
    • Savill, J.1    Dransfield, I.2    Hogg, N.3    Haslett, C.4
  • 123
    • 0036884424 scopus 로고    scopus 로고
    • A blast from the past: Clearance of apoptotic cells regulates immune responses
    • doi:10.1038/nri957
    • Savill, J., I. Dransfield, C. Gregory, and C. Haslett. 2002. A blast from the past: clearance of apoptotic cells regulates immune responses. Nat. Rev. Immunol. 2:965-975. doi:10.1038/nri957
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 965-975
    • Savill, J.1    Dransfield, I.2    Gregory, C.3    Haslett, C.4
  • 124
    • 20144363054 scopus 로고    scopus 로고
    • Phagocytosis of apoptotic cells by macrophages is impaired in atherosclerosis
    • doi:10.1161/01.ATV.0000166517.18801.a7
    • Schrijvers, D.M., G.R. De Meyer, M.M. Kockx, A.G. Herman, and W. Martinet. 2005. Phagocytosis of apoptotic cells by macrophages is impaired in atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 25:1256-1261. doi:10.1161/01.ATV.0000166517.18801.a7
    • (2005) Arterioscler. Thromb. Vasc. Biol. , vol.25 , pp. 1256-1261
    • Schrijvers, D.M.1    De Meyer, G.R.2    Kockx, M.M.3    Herman, A.G.4    Martinet, W.5
  • 126
    • 20144388376 scopus 로고    scopus 로고
    • Genetic variations in the gene encoding ELMO1 are associated with susceptibility to diabetic nephropathy
    • doi:10.2337/diabetes.54.4.1171
    • Shimazaki, A., Y. Kawamura, A. Kanazawa, A. Sekine, S. Saito, T. Tsunoda, D. Koya, T. Babazono, Y. Tanaka, M. Matsuda, et al. 2005. Genetic variations in the gene encoding ELMO1 are associated with susceptibility to diabetic nephropathy. Diabetes. 54:1171-1178. doi:10.2337/diabetes.54.4.1171
    • (2005) Diabetes , vol.54 , pp. 1171-1178
    • Shimazaki, A.1    Kawamura, Y.2    Kanazawa, A.3    Sekine, A.4    Saito, S.5    Tsunoda, T.6    Koya, D.7    Babazono, T.8    Tanaka, Y.9    Matsuda, M.10
  • 127
    • 70350728931 scopus 로고    scopus 로고
    • Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation
    • doi:10.1189/jlb.0609385
    • Solinas, G., G. Germano, A. Mantovani, and P. Allavena. 2009. Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation. J. Leukoc. Biol. 86:1065-1073. doi:10.1189/jlb.0609385
    • (2009) J. Leukoc. Biol. , vol.86 , pp. 1065-1073
    • Solinas, G.1    Germano, G.2    Mantovani, A.3    Allavena, P.4
  • 128
    • 0035899360 scopus 로고    scopus 로고
    • Structural mimicry in bacterial virulence
    • doi:10.1038/35089000
    • Stebbins, C.E., and J.E. Galán. 2001. Structural mimicry in bacterial virulence. Nature. 412:701-705. doi:10.1038/35089000
    • (2001) Nature , vol.412 , pp. 701-705
    • Stebbins, C.E.1    Galán, J.E.2
  • 129
    • 3042738397 scopus 로고    scopus 로고
    • Neuronal apoptotic bodies: Phagocytosis and degradation by primary microglial cells
    • Stolzing, A., and T. Grune. 2004. Neuronal apoptotic bodies: phagocytosis and degradation by primary microglial cells. FASEB J. 18:743-745.
    • (2004) FASEB J. , vol.18 , pp. 743-745
    • Stolzing, A.1    Grune, T.2
  • 130
    • 0028577208 scopus 로고
    • Immunohistochemical evidence for apoptosis in Alzheimer's disease
    • doi:10.1097/00001756-199412000-00031
    • Su, J.H., A.J. Anderson, B.J. Cummings, and C.W. Cotman. 1994. Immunohistochemical evidence for apoptosis in Alzheimer's disease. Neuroreport. 5:2529-2533. doi:10.1097/00001756-199412000-00031
    • (1994) Neuroreport , vol.5 , pp. 2529-2533
    • Su, J.H.1    Anderson, A.J.2    Cummings, B.J.3    Cotman, C.W.4
  • 131
    • 0037023693 scopus 로고    scopus 로고
    • Interaction of CED-6/GULP, an adapter protein involved in engulfment of apoptotic cells with CED-1 and CD91/low density lipoprotein receptor-related protein (LRP)
    • doi:10.1074/jbc.M109336200
    • Su, H.P., K. Nakada-Tsukui, A.C. Tosello-Trampont, Y. Li, G. Bu, P.M. Henson, and K.S. Ravichandran. 2002. Interaction of CED-6/GULP, an adapter protein involved in engulfment of apoptotic cells with CED-1 and CD91/low density lipoprotein receptor-related protein (LRP). J. Biol. Chem. 277:11772-11779. doi:10.1074/jbc.M109336200
    • (2002) J. Biol. Chem. , vol.277 , pp. 11772-11779
    • Su, H.P.1    Nakada-Tsukui, K.2    Tosello-Trampont, A.C.3    Li, Y.4    Bu, G.5    Henson, P.M.6    Ravichandran, K.S.7
  • 132
    • 9944228640 scopus 로고    scopus 로고
    • Allograft tolerance induced by donor apoptotic lymphocytes requires phagocytosis in the recipient
    • doi:10.1038/sj.cdd.4401500
    • Sun, E., Y. Gao, J. Chen, A.I. Roberts, X. Wang, Z. Chen, and Y. Shi. 2004. Allograft tolerance induced by donor apoptotic lymphocytes requires phagocytosis in the recipient. Cell Death Differ. 11:1258-1264. doi:10.1038/sj.cdd.4401500
    • (2004) Cell Death Differ. , vol.11 , pp. 1258-1264
    • Sun, E.1    Gao, Y.2    Chen, J.3    Roberts, A.I.4    Wang, X.5    Chen, Z.6    Shi, Y.7
  • 134
    • 27644537437 scopus 로고    scopus 로고
    • Consequences and therapeutic implications of macrophage apoptosis in atherosclerosis: The importance of lesion stage and phagocytic efficiency
    • doi:10.1161/01.ATV.0000184783.04864.9f
    • Tabas, I. 2005. Consequences and therapeutic implications of macrophage apoptosis in atherosclerosis: the importance of lesion stage and phagocytic efficiency. Arterioscler. Thromb. Vasc. Biol. 25:2255-2264. doi:10.1161/01.ATV.
    • (2005) Arterioscler. Thromb. Vasc. Biol. , vol.25 , pp. 2255-2264
    • Tabas, I.1
  • 135
    • 0037386810 scopus 로고    scopus 로고
    • High mobility group box chromosomal protein 1 plays a role in the pathogenesis of rheumatoid arthritis as a novel cytokine
    • doi:10.1002/art.10859
    • Taniguchi, N., K. Kawahara, K. Yone, T. Hashiguchi, M. Yamakuchi, M. Goto, K. Inoue, S. Yamada, K. Ijiri, S. Matsunaga, et al. 2003. High mobility group box chromosomal protein 1 plays a role in the pathogenesis of rheumatoid arthritis as a novel cytokine. Arthritis Rheum. 48:971-981. doi:10.1002/art. 10859
    • (2003) Arthritis Rheum. , vol.48 , pp. 971-981
    • Taniguchi, N.1    Kawahara, K.2    Yone, K.3    Hashiguchi, T.4    Yamakuchi, M.5    Goto, M.6    Inoue, K.7    Yamada, S.8    Ijiri, K.9    Matsunaga, S.10
  • 136
    • 73949086520 scopus 로고    scopus 로고
    • Adult neurogenesis, neural stem cells and Alzheimer's disease: Developments, limitations, problems and promises
    • doi:10.2174/156720509790147151
    • Taupin, P. 2009. Adult neurogenesis, neural stem cells and Alzheimer's disease: developments, limitations, problems and promises. Curr. Alzheimer Res. 6:461-470. doi:10.2174/156720509790147151
    • (2009) Curr. Alzheimer Res. , vol.6 , pp. 461-470
    • Taupin, P.1
  • 137
    • 0029086807 scopus 로고
    • DNA end labeling (TUNEL) in Huntington's disease and other neuropathological conditions
    • doi:10.1006/exnr.1995.1029
    • Thomas, L.B., D.J. Gates, E.K. Richfield, T.F. O'Brien, J.B. Schweitzer, and D.A. Steindler. 1995. DNA end labeling (TUNEL) in Huntington's disease and other neuropathological conditions. Exp. Neurol. 133:265-272. doi:10.1006/exnr.1995.1029
    • (1995) Exp. Neurol. , vol.133 , pp. 265-272
    • Thomas, L.B.1    Gates, D.J.2    Richfield, E.K.3    O'Brien, T.F.4    Schweitzer, J.B.5    Steindler, D.A.6
  • 138
    • 52449109523 scopus 로고    scopus 로고
    • Mertk receptor mutation reduces efferocytosis efficiency and promotes apoptotic cell accumulation and plaque necrosis in atherosclerotic lesions of apoe-/- mice
    • doi:10.1161/ATVBAHA.108.167197
    • Thorp, E., D. Cui, D.M. Schrijvers, G. Kuriakose, and I. Tabas. 2008. Mertk receptor mutation reduces efferocytosis efficiency and promotes apoptotic cell accumulation and plaque necrosis in atherosclerotic lesions of apoe-/- mice. Arterioscler. Thromb. Vasc. Biol. 28:1421-1428. doi:10.1161/ATVBAHA.108. 167197
    • (2008) Arterioscler. Thromb. Vasc. Biol. , vol.28 , pp. 1421-1428
    • Thorp, E.1    Cui, D.2    Schrijvers, D.M.3    Kuriakose, G.4    Tabas, I.5
  • 139
    • 0347379920 scopus 로고    scopus 로고
    • Engulfment of apoptotic cells is negatively regulated by Rhomediated signaling
    • doi:10.1074/jbc.M306079200
    • Tosello-Trampont, A.C., K. Nakada-Tsukui, and K.S. Ravichandran. 2003. Engulfment of apoptotic cells is negatively regulated by Rhomediated signaling. J. Biol. Chem. 278:49911-49919. doi:10.1074/jbc.M306079200
    • (2003) J. Biol. Chem. , vol.278 , pp. 49911-49919
    • Tosello-Trampont, A.C.1    Nakada-Tsukui, K.2    Ravichandran, K.S.3
  • 142
    • 33745121896 scopus 로고    scopus 로고
    • Burying the dead: The impact of failed apoptotic cell removal (efferocytosis) on chronic inflammatory lung disease
    • doi:10.1378/chest.129.6.1673
    • Vandivier, R.W., P.M. Henson, and I.S. Douglas. 2006. Burying the dead: the impact of failed apoptotic cell removal (efferocytosis) on chronic inflammatory lung disease. Chest. 129:1673-1682. doi:10.1378/chest.129.6.1673
    • (2006) Chest , vol.129 , pp. 1673-1682
    • Vandivier, R.W.1    Henson, P.M.2    Douglas, I.S.3
  • 145
    • 63749129513 scopus 로고    scopus 로고
    • In situ-targeting of dendritic cells with donor-derived apoptotic cells restrains indirect allorecognition and ameliorates allograft vasculopathy
    • doi:10.1371/journal.pone.0004940
    • Wang, Z., W.J. Shufesky, A. Montecalvo, S.J. Divito, A.T. Larregina, and A.E. Morelli. 2009. In situ-targeting of dendritic cells with donor-derived apoptotic cells restrains indirect allorecognition and ameliorates allograft vasculopathy. PLoS One. 4:e4940. doi:10.1371/journal.pone.0004940
    • (2009) PLoS One , vol.4
    • Wang, Z.1    Shufesky, W.J.2    Montecalvo, A.3    Divito, S.J.4    Larregina, A.T.5    Morelli, A.E.6
  • 147
    • 77952421433 scopus 로고    scopus 로고
    • Effect of transglutaminase 2 (TG2) deficiency on atherosclerotic plaque stability in the apolipoprotein e deficient mouse
    • doi:10.1016/j.atherosclerosis.2009.11.014
    • Williams, H., R.J. Pease, L.M. Newell, P.A. Cordell, R.M. Graham, M.T. Kearney, C.L. Jackson, and P.J. Grant. 2010. Effect of transglutaminase 2 (TG2) deficiency on atherosclerotic plaque stability in the apolipoprotein E deficient mouse. Atherosclerosis. 210:94-99. doi:10.1016/j.atherosclerosis.2009.11.014
    • (2010) Atherosclerosis , vol.210 , pp. 94-99
    • Williams, H.1    Pease, R.J.2    Newell, L.M.3    Cordell, P.A.4    Graham, R.M.5    Kearney, M.T.6    Jackson, C.L.7    Grant, P.J.8
  • 148
    • 0033836217 scopus 로고    scopus 로고
    • Phagocytic clearance of apoptotic neurons by microglia/brain macrophages in vitro: Involvement of lectin-, integrin-, and phosphatidylserine-mediated recognition
    • DOI 10.1046/j.1471-4159.2000.0751060.x
    • Witting, A., P. Müller, A. Herrmann, H. Kettenmann, and C. Nolte. 2000. Phagocytic clearance of apoptotic neurons by Microglia/Brain macrophages in vitro: involvement of lectin-, integrin-, and phosphatidylserine-mediated recognition. J. Neurochem. 75:1060-1070. doi:10.1046/j.1471-4159.2000.0751060.x (Pubitemid 30660494)
    • (2000) Journal of Neurochemistry , vol.75 , Issue.3 , pp. 1060-1070
    • Witting, A.1    Muller, P.2    Herrmann, A.3    Kettenmann, H.4    Nolte, C.5
  • 150
    • 77953312484 scopus 로고    scopus 로고
    • Aberrant splicing of the milk fat globule-EGF factor 8 (MFG-E8) gene in human systemic lupus erythematosus
    • Yamaguchi, H., T. Fujimoto, S. Nakamura, K. Ohmura, T. Mimori, F. Matsuda, and S. Nagata. 2010. Aberrant splicing of the milk fat globule-EGF factor 8 (MFG-E8) gene in human systemic lupus erythematosus. Eur. J. Immunol. 40:1778-1785.
    • (2010) Eur. J. Immunol. , vol.40 , pp. 1778-1785
    • Yamaguchi, H.1    Fujimoto, T.2    Nakamura, S.3    Ohmura, K.4    Mimori, T.5    Matsuda, F.6    Nagata, S.7
  • 151
    • 33745240385 scopus 로고    scopus 로고
    • In vivo detection of apoptotic cells in the testis using fluorescence labeled annexin V in a mouse model of testicular torsion
    • doi:10.1016/j.juro.2006.03.073
    • Yang, S.K., S. Attipoe, A.P. Klausner, R. Tian, D. Pan, T.A. Rich, T.T. Turner, W.D. Steers, and J.J. Lysiak. 2006. In vivo detection of apoptotic cells in the testis using fluorescence labeled annexin V in a mouse model of testicular torsion. J. Urol. 176:830-835. doi:10.1016/j.juro.2006.03.073
    • (2006) J. Urol. , vol.176 , pp. 830-835
    • Yang, S.K.1    Attipoe, S.2    Klausner, A.P.3    Tian, R.4    Pan, D.5    Rich, T.A.6    Turner, T.T.7    Steers, W.D.8    Lysiak, J.J.9
  • 152
    • 41749109981 scopus 로고    scopus 로고
    • Phagocytic receptor CED-1 initiates a signaling pathway for degrading engulfed apoptotic cells
    • doi:10.1371/journal.pbio.0060061
    • Yu, X., N. Lu, and Z. Zhou. 2008. Phagocytic receptor CED-1 initiates a signaling pathway for degrading engulfed apoptotic cells. PLoS Biol. 6:e61. doi:10.1371/journal.pbio.0060061
    • (2008) PLoS Biol , vol.6
    • Yu, X.1    Lu, N.2    Zhou, Z.3
  • 153
    • 0028953024 scopus 로고
    • Identification of neuronal programmed cell death in situ in the striatum of normal adult rat brain and its relationship to neuronal death during aging
    • doi:10.1016/0006-8993(95)00197-X
    • Zhang, L., G. Kokkonen, and G.S. Roth. 1995. Identification of neuronal programmed cell death in situ in the striatum of normal adult rat brain and its relationship to neuronal death during aging. Brain Res. 677:177-179. doi:10.1016/0006-8993(95)00197-X
    • (1995) Brain Res. , vol.677 , pp. 177-179
    • Zhang, L.1    Kokkonen, G.2    Roth, G.S.3
  • 154
    • 39149107803 scopus 로고    scopus 로고
    • Mechanisms and Functional Implications of Adult Neurogenesis
    • DOI 10.1016/j.cell.2008.01.033, PII S0092867408001347
    • Zhao, C., W. Deng, and F.H. Gage. 2008. Mechanisms and functional implications of adult neurogenesis. Cell. 132:645-660. doi:10.1016/j.cell.2008. 01.033 (Pubitemid 351253687)
    • (2008) Cell , vol.132 , Issue.4 , pp. 645-660
    • Zhao, C.1    Deng, W.2    Gage, F.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.