메뉴 건너뛰기




Volumn 424, Issue 6947, 2003, Pages 461-464

RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo

Author keywords

[No Author keywords available]

Indexed keywords

CATALYST ACTIVITY; CELLS; MORPHOLOGY;

EID: 0042674398     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature01817     Document Type: Article
Times cited : (305)

References (25)
  • 2
    • 17944376439 scopus 로고    scopus 로고
    • CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration
    • Gumienny, T.L. et al. CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration. Cell 107, 27-41 (2001).
    • (2001) Cell , vol.107 , pp. 27-41
    • Gumienny, T.L.1
  • 3
    • 0035487646 scopus 로고    scopus 로고
    • The C. elegans PH domain protein CED-12 regulates cytoskeletal reorganization via a Rho/Rac GTPase signaling pathway
    • Zhou, Z., Caron, E., Hartwieg, E., Hall, A. & Horvitz, R. The C. elegans PH domain protein CED-12 regulates cytoskeletal reorganization via a Rho/Rac GTPase signaling pathway. Dev. Cell 1, 477-489 (2001).
    • (2001) Dev. Cell , vol.1 , pp. 477-489
    • Zhou, Z.1    Caron, E.2    Hartwieg, E.3    Hall, A.4    Horvitz, R.5
  • 4
    • 0035487807 scopus 로고    scopus 로고
    • C. elegans CED-12 acts in the conserved CrkII/Dock180/Rac pathway to control cell migration and cell corpse engulfment
    • Wu, Y. C., Tsai, M. C., Cheng, L. C., Chou, C. J. & Weng, N. Y. C. elegans CED-12 acts in the conserved CrkII/Dock180/Rac pathway to control cell migration and cell corpse engulfment. Dev. Cell 1, 491-502 (2001).
    • (2001) Dev. Cell , vol.1 , pp. 491-502
    • Wu, Y.C.1    Tsai, M.C.2    Cheng, L.C.3    Chou, C.J.4    Weng, N.Y.5
  • 5
    • 0036045768 scopus 로고    scopus 로고
    • Unconventional Rac-GEF activity is mediated through the Dock180-Elmo complex
    • Brugnera, E. et al. Unconventional Rac-GEF activity is mediated through the Dock180-Elmo complex. Nature Cell Biol. 4, 574-582 (2002).
    • (2002) Nature Cell Biol. , vol.4 , pp. 574-582
    • Brugnera, E.1
  • 6
    • 0037115488 scopus 로고    scopus 로고
    • Identification of an evolutionarily conserved superfamily of Dock180-related proteins with guanine nucleotide exchange activity
    • Cote, J. F. & Vuori, K. Identification of an evolutionarily conserved superfamily of Dock180-related proteins with guanine nucleotide exchange activity. J. Cell Sci. 115, 4901-4913 (2002).
    • (2002) J. Cell Sci. , vol.115 , pp. 4901-4913
    • Cote, J.F.1    Vuori, K.2
  • 7
    • 0031815909 scopus 로고    scopus 로고
    • RhoG GTPase controls a pathway that independently activates Rac 1 and Cdc42Hs
    • Gauthier-Rouviere, C. et al. RhoG GTPase controls a pathway that independently activates Rac1 and Cdc42Hs. Mol. Biol. Cell 9, 1379-1394 (1998).
    • (1998) Mol. Biol. Cell , vol.9 , pp. 1379-1394
    • Gauthier-Rouviere, C.1
  • 8
    • 0034053503 scopus 로고    scopus 로고
    • TrioGEF1 controls Rac- and Cdc42-dependent cell structures through the direct activation of RhoG
    • Blangy, A., Schmidt, V. S., Debant, A., Gauthier-Rouviere, C. & Fort, P. TrioGEF1 controls Rac- and Cdc42-dependent cell structures through the direct activation of RhoG. J. Cell Sci. 113, 729-739 (2000).
    • (2000) J. Cell Sci. , vol.113 , pp. 729-739
    • Blangy, A.1    Schmidt, V.S.2    Debant, A.3    Gauthier-Rouviere, C.4    Fort, P.5
  • 9
    • 0033835027 scopus 로고    scopus 로고
    • Small GTPase RhoG is a key regulator for neurite outgrowth in PC 12 cells
    • Katoh, H. et al. Small GTPase RhoG is a key regulator for neurite outgrowth in PC12 cells. Mol. Cell Biol. 20, 7378-7387 (2000).
    • (2000) Mol. Cell Biol. , vol.20 , pp. 7378-7387
    • Katoh, H.1
  • 10
    • 0037133037 scopus 로고    scopus 로고
    • The human Rho-GEF Trio and its target GTPase RhoG are involved in the NGF pathway, leading to neurite outgrowth
    • Estrach, S. et al. The human Rho-GEF Trio and its target GTPase RhoG are involved in the NGF pathway, leading to neurite outgrowth. Curr. Biol. 12, 307-312 (2002).
    • (2002) Curr. Biol. , vol.12 , pp. 307-312
    • Estrach, S.1
  • 11
    • 0037104721 scopus 로고    scopus 로고
    • Kalirin Db1-homology guanine nucleotide exchange factor 1 domain initiates new axon outgrowths via RhoG-mediated mechanisms
    • May, V., Schiller, M. R., Eipper, B. A. & Mains, R. E. Kalirin Db1-homology guanine nucleotide exchange factor 1 domain initiates new axon outgrowths via RhoG-mediated mechanisms. J. Neurosci. 22, 6980-6990 (2002).
    • (2002) J. Neurosci. , vol.22 , pp. 6980-6990
    • May, V.1    Schiller, M.R.2    Eipper, B.A.3    Mains, R.E.4
  • 12
    • 0037461959 scopus 로고    scopus 로고
    • RhoG regulates gene expression and the actin cytoskeleton in lymphocytes
    • Vigorito, E. et al. RhoG regulates gene expression and the actin cytoskeleton in lymphocytes. Oncogene 22, 330-342 (2003).
    • (2003) Oncogene , vol.22 , pp. 330-342
    • Vigorito, E.1
  • 13
    • 0028078824 scopus 로고
    • A brain serine/threonine protein kinase activated by Cdc 42 and Rac1
    • Manser, E., Leung, T., Salihuddin, H., Zhao, Z. S. & Lim, L. A brain serine/threonine protein kinase activated by Cdc42 and Rac1. Nature 367, 40-46 (1994).
    • (1994) Nature , vol.367 , pp. 40-46
    • Manser, E.1    Leung, T.2    Salihuddin, H.3    Zhao, Z.S.4    Lim, L.5
  • 14
    • 0029889591 scopus 로고    scopus 로고
    • Rhotekin, a new putative target for Rho bearing homology to a serine/threonone kinase PKN, and Rhophilin in the Rho-binding domain
    • Reid, T. et al. Rhotekin, a new putative target for Rho bearing homology to a serine/threonone kinase PKN, and Rhophilin in the Rho-binding domain. J. Biol. Chem. 271, 13556-13560 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 13556-13560
    • Reid, T.1
  • 15
    • 0029926307 scopus 로고    scopus 로고
    • Dock180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane
    • Hasegawa, H. et al. Dock180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane. Mol. Cell. Biol. 16, 1770-1776 (1996).
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1770-1776
    • Hasegawa, H.1
  • 16
    • 0032213110 scopus 로고    scopus 로고
    • Activation of Rac1 by a Crk SH3-binding protein, DOCK 180
    • Kiyokawa, E. et al. Activation of Rac1 by a Crk SH3-binding protein, DOCK180. Genes Dev. 12, 3331-3336 (1998).
    • (1998) Genes Dev. , vol.12 , pp. 3331-3336
    • Kiyokawa, E.1
  • 17
    • 0032544426 scopus 로고    scopus 로고
    • Cas complex
    • Cas complex. J. Biol. Chem. 273, 24479-24484 (1998).
    • (1998) J. Biol. Chem. , vol.273 , pp. 24479-24484
    • Kiyokawa, E.1
  • 18
    • 0033625871 scopus 로고    scopus 로고
    • 5 integrin recruits the CrkII-Dock180-Rac 1 complex for phagocytosis of apoptotic cells
    • 5 integrin recruits the CrkII-Dock180-Rac1 complex for phagocytosis of apoptotic cells. Nature Cell Biol. 2, 899-905 (2000).
    • (2000) Nature Cell Biol. , vol.2 , pp. 899-905
    • Albert, M.L.1    Kim, J.2    Birge, R.B.3
  • 20
    • 0032572557 scopus 로고    scopus 로고
    • Integrin-mediated signals regulated by members of the Rho family of GTPases
    • Clark, E. A., King, W. G., Brugge, J. S., Symons, M. & Hynes, R. O. Integrin-mediated signals regulated by members of the Rho family of GTPases. J. Cell Biol. 142, 573-586 (1998).
    • (1998) J. Cell Biol. , vol.142 , pp. 573-586
    • Clark, E.A.1    King, W.G.2    Brugge, J.S.3    Symons, M.4    Hynes, R.O.5
  • 21
    • 0031844821 scopus 로고    scopus 로고
    • Activation of Rac and Cdc 42 by integrins mediates cell spreading
    • Price, L. S., Leng, J., Schwartz, M. A. & Bokoch, G. M. Activation of Rac and Cdc42 by integrins mediates cell spreading. Mol. Biol. Cell 9, 1863-1871 (1998).
    • (1998) Mol. Biol. Cell , vol.9 , pp. 1863-1871
    • Price, L.S.1    Leng, J.2    Schwartz, M.A.3    Bokoch, G.M.4
  • 22
    • 0035195553 scopus 로고    scopus 로고
    • Three C. elegans Rac proteins and several alternative Rac regulators control axon guidance, cell migration and apoptotic cell phagocytosis
    • Lundquist, E. A. et al. Three C. elegans Rac proteins and several alternative Rac regulators control axon guidance, cell migration and apoptotic cell phagocytosis. Development 128, 4475-4488 (2001).
    • (2001) Development , vol.128 , pp. 4475-4488
    • Lundquist, E.A.1
  • 23
    • 0036392188 scopus 로고    scopus 로고
    • Distinct Rac activation pathways control Caenorhabditis elegans cell migration and axon outgrowth
    • Wu, Y. C., Cheng, T. W., Lee, M. C. & Weng, N. Y. Distinct Rac activation pathways control Caenorhabditis elegans cell migration and axon outgrowth. Dev. Biol. 250, 145-155 (2002).
    • (2002) Dev. Biol. , vol.250 , pp. 145-155
    • Wu, Y.C.1    Cheng, T.W.2    Lee, M.C.3    Weng, N.Y.4
  • 24
    • 0032549710 scopus 로고    scopus 로고
    • UNC-73 activates the Rac GTPase and is required for cell and growth cone migrations in C. elegans
    • Steven, R. et al. UNC-73 activates the Rac GTPase and is required for cell and growth cone migrations in C. elegans. Cell 92, 785-795 (1998).
    • (1998) Cell , vol.92 , pp. 785-795
    • Steven, R.1
  • 25
    • 0036232358 scopus 로고    scopus 로고
    • Socius is a novel Rnd GTPase-interacting protein involved in disassembly of actin stress fibers
    • Katoh, H., Harada, A., Mori, K. & Negishi, M. Socius is a novel Rnd GTPase-interacting protein involved in disassembly of actin stress fibers. Mol. Cell. Biol. 22, 2952-2964 (2002).
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 2952-2964
    • Katoh, H.1    Harada, A.2    Mori, K.3    Negishi, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.