-
1
-
-
0034987702
-
Malignant glioma: Genetics and biology of a grave matter
-
Maher EA, Furnari FB, Bachoo RM, et al. Malignant glioma: genetics and biology of a grave matter. Genes Dev 2001;15:1311-33.
-
(2001)
Genes Dev
, vol.15
, pp. 1311-1333
-
-
Maher, E.A.1
Furnari, F.B.2
Bachoo, R.M.3
-
2
-
-
0038179723
-
Cost of migration: Invasion of malignant gliomas and implications for treatment
-
Giese A, Bjerkvig R, Berens ME, Westphal M. Cost of migration: invasion of malignant gliomas and implications for treatment. J Clin Oncol 2003;21:1624-36.
-
(2003)
J Clin Oncol
, vol.21
, pp. 1624-1636
-
-
Giese, A.1
Bjerkvig, R.2
Berens, M.E.3
Westphal, M.4
-
3
-
-
0037069690
-
Rho GTPases in cell biology
-
Etienne-Manneville S, Hall A. Rho GTPases in cell biology. Nature 2002;420:629-35.
-
(2002)
Nature
, vol.420
, pp. 629-635
-
-
Etienne-Manneville, S.1
Hall, A.2
-
4
-
-
33750582087
-
The in vitro influences of neurotensin on the motility characteristics of human U373 glioblastoma cells
-
Servotte S, Camby I, Debeir O, et al. The in vitro influences of neurotensin on the motility characteristics of human U373 glioblastoma cells. Neuropathol Appl Neurobiol 2006;32:575-84.
-
(2006)
Neuropathol Appl Neurobiol
, vol.32
, pp. 575-584
-
-
Servotte, S.1
Camby, I.2
Debeir, O.3
-
5
-
-
33750300516
-
Increased fibroblast growth factor-inducible 14 expression levels promote glioma cell invasion via Rac1 and nuclear factor-κB and correlate with poor patient outcome
-
Tran NL, McDonough WS, Savitch BA, et al. Increased fibroblast growth factor-inducible 14 expression levels promote glioma cell invasion via Rac1 and nuclear factor-κB and correlate with poor patient outcome. Cancer Res 2006;66:9535-42.
-
(2006)
Cancer Res
, vol.66
, pp. 9535-9542
-
-
Tran, N.L.1
McDonough, W.S.2
Savitch, B.A.3
-
6
-
-
28344456263
-
Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion
-
Chan AY, Coniglio SJ, Chuang YY, et al. Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion. Oncogene 2005;24:7821-9.
-
(2005)
Oncogene
, vol.24
, pp. 7821-7829
-
-
Chan, A.Y.1
Coniglio, S.J.2
Chuang, Y.Y.3
-
7
-
-
25444528940
-
Inhibition of Rhokinase affects astrocytoma morphology, motility, and invasion through activation of Rac1
-
Salhia B, Rutten F, Nakada M, et al. Inhibition of Rhokinase affects astrocytoma morphology, motility, and invasion through activation of Rac1. Cancer Res 2005;65:8792-800.
-
(2005)
Cancer Res
, vol.65
, pp. 8792-8800
-
-
Salhia, B.1
Rutten, F.2
Nakada, M.3
-
8
-
-
1042278148
-
Engagement of CD44 promotes Rac activation and CD44 cleavage during tumor cell migration
-
Murai T, Miyazaki Y, Nishinakamura H, et al. Engagement of CD44 promotes Rac activation and CD44 cleavage during tumor cell migration. J Biol Chem 2004;279:4541-50.
-
(2004)
J Biol Chem
, vol.279
, pp. 4541-4550
-
-
Murai, T.1
Miyazaki, Y.2
Nishinakamura, H.3
-
9
-
-
33748997415
-
Ephrin-B3 ligand promotes glioma invasion through activation of Rac1
-
Nakada M, Drake KL, Nakada S, Niska JA, Berens ME. Ephrin-B3 ligand promotes glioma invasion through activation of Rac1. Cancer Res 2006;66:8492-500.
-
(2006)
Cancer Res
, vol.66
, pp. 8492-8500
-
-
Nakada, M.1
Drake, K.L.2
Nakada, S.3
Niska, J.A.4
Berens, M.E.5
-
10
-
-
27744577845
-
Cell migration and invasion assays
-
Valster A, Tran NL, Nakada M, et al. Cell migration and invasion assays. Methods 2005;37:208-15.
-
(2005)
Methods
, vol.37
, pp. 208-215
-
-
Valster, A.1
Tran, N.L.2
Nakada, M.3
-
11
-
-
0345731237
-
Cell migration: Rho GTPases lead the way
-
Raftopoulou M, Hall A. Cell migration: Rho GTPases lead the way. Dev Biol 2004;265:23-32.
-
(2004)
Dev Biol
, vol.265
, pp. 23-32
-
-
Raftopoulou, M.1
Hall, A.2
-
12
-
-
27844604200
-
GTPases and the control of cell behaviour
-
Hall A. Rho GTPases and the control of cell behaviour. Biochem Soc Trans 2005;33:891-5.
-
(2005)
Biochem Soc Trans
, vol.33
, pp. 891-895
-
-
Rho, H.A.1
-
13
-
-
27944445790
-
CZH proteins: A new family of Rho-GEFs
-
Meller N, Merlot S, Guda C. CZH proteins: a new family of Rho-GEFs. J Cell Sci 2005;118:4937-46.
-
(2005)
J Cell Sci
, vol.118
, pp. 4937-4946
-
-
Meller, N.1
Merlot, S.2
Guda, C.3
-
14
-
-
0029926307
-
DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane
-
Hasegawa H, Kiyokawa E, Tanaka S, et al. DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane. Mol Cell Biol 1996;16:1770-6.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 1770-1776
-
-
Hasegawa, H.1
Kiyokawa, E.2
Tanaka, S.3
-
15
-
-
0032213110
-
Activation of Rac1 by a Crk SH3-binding protein, DOCK180
-
Kiyokawa E, Hashimoto Y, Kobayashi S, et al. Activation of Rac1 by a Crk SH3-binding protein, DOCK180. Genes Dev 1998;12:3331-6.
-
(1998)
Genes Dev
, vol.12
, pp. 3331-3336
-
-
Kiyokawa, E.1
Hashimoto, Y.2
Kobayashi, S.3
-
16
-
-
0030816709
-
Drosophila myoblast city encodes a conserved protein that is essential for myoblast fusion, dorsal closure, and cytoskeletal organization
-
Erickson MR, Galletta BJ, Abmayr SM. Drosophila myoblast city encodes a conserved protein that is essential for myoblast fusion, dorsal closure, and cytoskeletal organization. J Cell Biol 1997;138:589-603.
-
(1997)
J Cell Biol
, vol.138
, pp. 589-603
-
-
Erickson, M.R.1
Galletta, B.J.2
Abmayr, S.M.3
-
17
-
-
0032213953
-
Myoblast city, the Drosophila homolog of DOCK180/CED-5, is required in a Rac signaling pathway utilized for multiple developmental processes
-
Nolan KM, Barrett K, Lu Y, et al. Myoblast city, the Drosophila homolog of DOCK180/CED-5, is required in a Rac signaling pathway utilized for multiple developmental processes. Genes Dev 1998;12:3337-42.
-
(1998)
Genes Dev
, vol.12
, pp. 3337-3342
-
-
Nolan, K.M.1
Barrett, K.2
Lu, Y.3
-
18
-
-
0032473981
-
-
Wu YC, Horvitz HR. C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180. Nature 1998;392:501-4.
-
Wu YC, Horvitz HR. C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180. Nature 1998;392:501-4.
-
-
-
-
19
-
-
0033625871
-
αvβ5 integrin recruits the CrkII-Dock180-1 complex for phagocytosis of apoptotic cells
-
Albert ML, Kim JI, Birge RB. αvβ5 integrin recruits the CrkII-Dock180-1 complex for phagocytosis of apoptotic cells. Nat Cell Biol 2000;2:899-905.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 899-905
-
-
Albert, M.L.1
Kim, J.I.2
Birge, R.B.3
-
20
-
-
2542492064
-
Temporal dissection of β1-integrin signaling indicates a role for p130Cas-Crk in filopodia formation
-
Gustavsson A, Yuan M, Fallman M. Temporal dissection of β1-integrin signaling indicates a role for p130Cas-Crk in filopodia formation. J Biol Chem 2004;279:22893-901.
-
(2004)
J Biol Chem
, vol.279
, pp. 22893-22901
-
-
Gustavsson, A.1
Yuan, M.2
Fallman, M.3
-
21
-
-
0036045768
-
Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex
-
Brugnera E, Haney L, Grimsley C, et al. Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex. Nat Cell Biol 2002;4:574-82.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 574-582
-
-
Brugnera, E.1
Haney, L.2
Grimsley, C.3
-
22
-
-
0037115488
-
Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity
-
Cote JF, Vuori K. Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity. J Cell Sci 2002;115:4901-13.
-
(2002)
J Cell Sci
, vol.115
, pp. 4901-4913
-
-
Cote, J.F.1
Vuori, K.2
-
23
-
-
32144455201
-
In vitro guanine nucleotide exchange activity of DHR-2/DOCKER/CZH2 domains
-
Cote JF, Vuori K. In vitro guanine nucleotide exchange activity of DHR-2/DOCKER/CZH2 domains. Methods Enzymol 2006;406:41-57.
-
(2006)
Methods Enzymol
, vol.406
, pp. 41-57
-
-
Cote, J.F.1
Vuori, K.2
-
24
-
-
17944376439
-
CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration
-
Gumienny TL, Brugnera E, Tosello-Trampont AC, et al. CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration. Cell 2001;107:27-41.
-
(2001)
Cell
, vol.107
, pp. 27-41
-
-
Gumienny, T.L.1
Brugnera, E.2
Tosello-Trampont, A.C.3
-
25
-
-
10744223552
-
Dock180 and ELMO1 proteins cooperate to promote evolutionarily conserved Rac-dependent cell migration
-
Grimsley CM, Kinchen JM, Tosello-Trampont AC, et al. Dock180 and ELMO1 proteins cooperate to promote evolutionarily conserved Rac-dependent cell migration. J Biol Chem 2004;279:6087-97.
-
(2004)
J Biol Chem
, vol.279
, pp. 6087-6097
-
-
Grimsley, C.M.1
Kinchen, J.M.2
Tosello-Trampont, A.C.3
-
26
-
-
0030728479
-
Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain
-
Furnari FB, Lin H, Huang HS, Cavenee WK. Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain. Proc Natl Acad Sci U S A 1997;94:12479-84.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 12479-12484
-
-
Furnari, F.B.1
Lin, H.2
Huang, H.S.3
Cavenee, W.K.4
-
27
-
-
0035392982
-
Formation of intracranial tumors by genetically modified human astrocytes defines four pathways critical in the development of human anaplastic astrocytoma
-
Sonoda Y, Ozawa T, Hirose Y, et al. Formation of intracranial tumors by genetically modified human astrocytes defines four pathways critical in the development of human anaplastic astrocytoma. Cancer Res 2001;61:4956-60.
-
(2001)
Cancer Res
, vol.61
, pp. 4956-4960
-
-
Sonoda, Y.1
Ozawa, T.2
Hirose, Y.3
-
28
-
-
14644399862
-
Up-regulation of angiopoietin-2, matrix metalloprotease-2, membrane type 1 metalloprotease, and laminin 5γ2 correlates with the invasiveness of human glioma
-
Guo P, Imanishi Y, Cackowski FC, et al. Up-regulation of angiopoietin-2, matrix metalloprotease-2, membrane type 1 metalloprotease, and laminin 5γ2 correlates with the invasiveness of human glioma. Am J Pathol 2005;166:877-90.
-
(2005)
Am J Pathol
, vol.166
, pp. 877-890
-
-
Guo, P.1
Imanishi, Y.2
Cackowski, F.C.3
-
29
-
-
33645239312
-
Elmo1 inhibits ubiquitylation of Dock180
-
Makino Y, Tsuda M, Ichihara S, et al. Elmo1 inhibits ubiquitylation of Dock180. J Cell Sci 2006;119:923-32.
-
(2006)
J Cell Sci
, vol.119
, pp. 923-932
-
-
Makino, Y.1
Tsuda, M.2
Ichihara, S.3
-
30
-
-
19344363916
-
HIV-1 Nef binds the DOCK2-1 complex to activate rac and inhibit lymphocyte chemotaxis
-
Janardhan A, Swigut T, Hill B, Myers MP, Skowronski J. HIV-1 Nef binds the DOCK2-1 complex to activate rac and inhibit lymphocyte chemotaxis. PLoS Biol 2004;2:E6.
-
(2004)
PLoS Biol
, vol.2
-
-
Janardhan, A.1
Swigut, T.2
Hill, B.3
Myers, M.P.4
Skowronski, J.5
-
31
-
-
0041806539
-
Angiopoietin-2 induces human glioma invasion through the activation of matrix metalloprotease-2
-
Hu B, Guo P, Fang Q, et al. Angiopoietin-2 induces human glioma invasion through the activation of matrix metalloprotease-2. Proc Natl Acad Sci U S A 2003;100:8904-9.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 8904-8909
-
-
Hu, B.1
Guo, P.2
Fang, Q.3
-
32
-
-
9144232309
-
Molecular mechanisms of glioma cell migration and invasion
-
Demuth T, Berens ME. Molecular mechanisms of glioma cell migration and invasion. J Neurooncol 2004;70:217-28.
-
(2004)
J Neurooncol
, vol.70
, pp. 217-228
-
-
Demuth, T.1
Berens, M.E.2
-
34
-
-
12344252751
-
Mechanisms of cancer cell invasion
-
Sahai E. Mechanisms of cancer cell invasion. Curr Opin Genet Dev 2005;15:87-96.
-
(2005)
Curr Opin Genet Dev
, vol.15
, pp. 87-96
-
-
Sahai, E.1
-
35
-
-
33745297408
-
New signals from the invasive front
-
Christofori G. New signals from the invasive front. Nature 2006;441:444-50.
-
(2006)
Nature
, vol.441
, pp. 444-450
-
-
Christofori, G.1
-
36
-
-
0033952759
-
Growth factors in gliomas revisited
-
discussion 37-8
-
Hamel W, Westphal M. Growth factors in gliomas revisited. Acta Neurochir (Wien) 2000;142:113-37; discussion 37-8.
-
(2000)
Acta Neurochir (Wien)
, vol.142
, pp. 113-137
-
-
Hamel, W.1
Westphal, M.2
-
37
-
-
19044397160
-
Epidermal growth factor receptor and Ink4a/Arf: Convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis
-
Bachoo RM, Maher EA, Ligon KL, et al. Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis. Cancer Cell 2002;1:269-77.
-
(2002)
Cancer Cell
, vol.1
, pp. 269-277
-
-
Bachoo, R.M.1
Maher, E.A.2
Ligon, K.L.3
-
38
-
-
33747885901
-
High-grade glioma formation results from postnatal Pten loss or mutant epidermal growth factor receptor expression in a transgenic mouse glioma model
-
Wei Q, Clarke L, Scheidenhelm DK, et al. High-grade glioma formation results from postnatal Pten loss or mutant epidermal growth factor receptor expression in a transgenic mouse glioma model. Cancer Res 2006;66:7429-37.
-
(2006)
Cancer Res
, vol.66
, pp. 7429-7437
-
-
Wei, Q.1
Clarke, L.2
Scheidenhelm, D.K.3
-
39
-
-
33644877500
-
Regulation of glioma cell migration by serine-phosphorylated P311
-
McDonough WS, Tran NL, Berens ME. Regulation of glioma cell migration by serine-phosphorylated P311. Neoplasia 2005;7:862-72.
-
(2005)
Neoplasia
, vol.7
, pp. 862-872
-
-
McDonough, W.S.1
Tran, N.L.2
Berens, M.E.3
-
40
-
-
13444252631
-
GEF means go: Turning on RHO GTPases with guanine nucleotide-exchange factors
-
Rossman KL, Der CJ, Sondek J. GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors. Nat Rev Mol Cell Biol 2005;6:167-80.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 167-180
-
-
Rossman, K.L.1
Der, C.J.2
Sondek, J.3
-
41
-
-
13444275480
-
Microregional extracellular matrix heterogeneity in brain modulates glioma cell invasion
-
Bellail AC, Hunter SB, Brat DJ, Tan C, Van Meir EG. Microregional extracellular matrix heterogeneity in brain modulates glioma cell invasion. Int J Biochem Cell Biol 2004;36:1046-69.
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 1046-1069
-
-
Bellail, A.C.1
Hunter, S.B.2
Brat, D.J.3
Tan, C.4
Van Meir, E.G.5
-
42
-
-
0027989375
-
Determinants of human astrocytoma migration
-
Giese A, Rief M, Loo M, Berens M. Determinants of human astrocytoma migration. Cancer Res 1994;54:3897-904.
-
(1994)
Cancer Res
, vol.54
, pp. 3897-3904
-
-
Giese, A.1
Rief, M.2
Loo, M.3
Berens, M.4
-
43
-
-
0041737535
-
Molecular mechanisms of glioma invasiveness: The role of proteases
-
Rao JS. Molecular mechanisms of glioma invasiveness: the role of proteases. Nat Rev Cancer 2003;3:489-501.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 489-501
-
-
Rao, J.S.1
-
44
-
-
0042674398
-
RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo
-
Katoh H, Negishi M. RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo. Nature 2003;424:461-4.
-
(2003)
Nature
, vol.424
, pp. 461-464
-
-
Katoh, H.1
Negishi, M.2
|