Requirement for Rho GTPases and PI 3-kinases during apoptotic cell phagocytosis by macrophages

Current Biology

Volumn 11, Issue 3, 2001, Pages 195-199

  Leverrier, Yann ^a   Ridley, Anne J ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; CLOSTRIDIUM DIFFICILE; MAMMALIA; MURINAE;

EID: 0035128074     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(01)00047-1     Document Type: Article

References (29)

1. Apoptosis: The importance of being eaten
2. Phosphoinositide 3-kinases: A conserved family of signal transducers
3. Rho GTPases and the actin cytoskeleton
4. Regulation of apoptosis in interleukin-3-dependent hemopoietic cells by interleukin-3 and calcium ionophores
5. Role of PI3-kinase in Bcl-X induction and apoptosis inhibition mediated by IL-3 or IGF-1 in Baf-3 cells
6. Different populations of macrophages use either the vitronectin receptor or the phosphatidylserine receptor to recognize and remove apoptotic cells
7. Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases
8. Molecular definition of distinct cytoskeletal structures involved in complement- and Fc receptor-mediated phagocytosis in macrophages
9. A receptor for phosphatidylserine-specific clearance of apoptotic cells
10. Multiple systems for recognition of apoptotic lymphocytes by macrophages
11. Requirements for both Rac1 and Cdc42 in membrane ruffling and phagocytosis in leukocytes
12. Fc receptor-mediated phagocytosis requires CDC42 and Rac1
13. Rho is required for the initiation of calcium signaling and phagocytosis by Fcgamma receptors in macrophages
14. Glucosylation of Rho proteins by Clostridium difficile toxin B
15. Asparagine residue in the rho gene product is the modification site for botulinum ADP-ribosyltransferase
16. A role for Cdc42 in macrophage chemotaxis
17. Rho family GTPases and neuronal growth cone remodelling: Relationship between increased complexity induced by Cdc42Hs, Rac1, and acetylcholine and collapse induced by RhoA and lysophosphatidic acid
18. CED-2/Crkll and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans
19. Distinct PI(3)Ks mediate mitogenic signalling and cell migration in macrophages
20. A requirement for phosphatidylinositol 3-kinase in pseudopod extension
21. A role for phosphoinositide 3-kinase in the completion of macropinocytosis and phagocytosis by macrophages
22. PI3-kinase inhibition: A target for drug development?
23. Signalling through phosphoinositide 3-kinases: The lipids take centre stage
24. Mechanisms of phagocytosis in macrophages
25. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF
26. Transcriptional and translational regulation of inflammatory mediator production by endogenous TGF-beta in macrophages that have ingested apoptotic cells
27. Autophagic and apoptotic types of programmed cell death exhibit different fates of cytoskeletal filaments
28. Actin is cleaved during constitutive apoptosis
29. Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak