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Volumn 285, Issue 6 29-6, 2003, Pages

Statin-mediated correction of STAT1 signaling and inducible nitric oxide synthase expression in cystic fibrosis epithelial cells

Author keywords

GTPase; Isoprenoid; Mevastatin; Protein inhibitor of activated signal transducer and activator of transcription 1; RhoA

Indexed keywords

CHOLESTEROL; COMPACTIN; ISOPRENOID; NITRIC OXIDE SYNTHASE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; STAT1 PROTEIN;

EID: 0345358534     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.00127.2003     Document Type: Article
Times cited : (60)

References (33)
  • 1
    • 2042544816 scopus 로고    scopus 로고
    • Post-translational processing of RhoA
    • Backlund PS. Post-translational processing of RhoA. J Biol Chem 272: 33175-33180, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 33175-33180
    • Backlund, P.S.1
  • 2
    • 0035929556 scopus 로고    scopus 로고
    • Cystic fibrosis transmembrane regulator regulates uptake of sphingoid base phosphates and lysophosphatidic acid: Modulation of cellular activity of sphingosine 1-phosphate
    • Boujaoude LC, Bradshaw-Wilder C, Mao C, Cohn J, Ogretmen B, Hannun YA, and Obeid LM. Cystic fibrosis transmembrane regulator regulates uptake of sphingoid base phosphates and lysophosphatidic acid: modulation of cellular activity of sphingosine 1-phosphate. J Biol Chem 276: 35258-35264, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 35258-35264
    • Boujaoude, L.C.1    Bradshaw-Wilder, C.2    Mao, C.3    Cohn, J.4    Ogretmen, B.5    Hannun, Y.A.6    Obeid, L.M.7
  • 3
    • 0032135143 scopus 로고    scopus 로고
    • Overproduction of the CFTR R domain leads to increased levels of asialoGM1 and increased Pseudomonas aeruginosa binding by epithelial cells
    • Bryan R, Kube D, Perez A, Davis P, and Prince A. Overproduction of the CFTR R domain leads to increased levels of asialoGM1 and increased Pseudomonas aeruginosa binding by epithelial cells. Am J Respir Cell Mol Biol 19: 269-277, 1998.
    • (1998) Am J Respir Cell Mol Biol , vol.19 , pp. 269-277
    • Bryan, R.1    Kube, D.2    Perez, A.3    Davis, P.4    Prince, A.5
  • 4
    • 0036236401 scopus 로고    scopus 로고
    • Reduction of neuronal and inducible nitric oxide synthase gene expression in patients with cystic fibrosis
    • Dotsch J, Puls J, Klimek T, and Rascher W. Reduction of neuronal and inducible nitric oxide synthase gene expression in patients with cystic fibrosis. Eur Arch Otorhinolaryngol 259: 222-226, 2002.
    • (2002) Eur Arch Otorhinolaryngol , vol.259 , pp. 222-226
    • Dotsch, J.1    Puls, J.2    Klimek, T.3    Rascher, W.4
  • 7
    • 0035798543 scopus 로고    scopus 로고
    • Chemoattractant-stimulated NF-kappaB activation is dependent on the low molecular weight GTPase RhoA
    • Huang S, Chen LY, Zuraw BL, Ye RD, and Pan ZK. Chemoattractant-stimulated NF-kappaB activation is dependent on the low molecular weight GTPase RhoA. J Biol Chem 276: 40977-40981, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 40977-40981
    • Huang, S.1    Chen, L.Y.2    Zuraw, B.L.3    Ye, R.D.4    Pan, Z.K.5
  • 8
    • 0034118853 scopus 로고    scopus 로고
    • A p160ROCK-specific inhibitor, Y-27632, attenuates rat hepatic stellate cell growth
    • Iwamoto H, Nakamuta M, Tada S, Sugimoto R, Enjoji M, and Nawata H. A p160ROCK-specific inhibitor, Y-27632, attenuates rat hepatic stellate cell growth. J Hepatol 32: 762-770, 2000.
    • (2000) J Hepatol , vol.32 , pp. 762-770
    • Iwamoto, H.1    Nakamuta, M.2    Tada, S.3    Sugimoto, R.4    Enjoji, M.5    Nawata, H.6
  • 9
    • 0034789730 scopus 로고    scopus 로고
    • Involvement of PIAS1 in the sumoylation of tumor suppressor p53
    • Kahyo T, Nishida T, and Yasuda H. Involvement of PIAS1 in the sumoylation of tumor suppressor p53. Mol Cell 8: 713-718, 2001.
    • (2001) Mol Cell , vol.8 , pp. 713-718
    • Kahyo, T.1    Nishida, T.2    Yasuda, H.3
  • 10
    • 0032531160 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase expression is reduced in cystic fibrosis murine and human airway epithelial cells
    • Kelley TJ and Drumm ML. Inducible nitric oxide synthase expression is reduced in cystic fibrosis murine and human airway epithelial cells. J Clin Invest 102: 1200-1207, 1998.
    • (1998) J Clin Invest , vol.102 , pp. 1200-1207
    • Kelley, T.J.1    Drumm, M.L.2
  • 11
    • 0035201671 scopus 로고    scopus 로고
    • Reduced Smad3 protein expression and altered transforming growth factor-betal-mediated signaling in cystic fibrosis epithelial cells
    • Kelley TJ, Elmer HL, and Corey DA. Reduced Smad3 protein expression and altered transforming growth factor-betal-mediated signaling in cystic fibrosis epithelial cells. Am J Respir Cell Mol Biol 25: 732-738, 2001.
    • (2001) Am J Respir Cell Mol Biol , vol.25 , pp. 732-738
    • Kelley, T.J.1    Elmer, H.L.2    Corey, D.A.3
  • 12
    • 0033846368 scopus 로고    scopus 로고
    • In vivo alterations of IFN regulatory factor-1 and PIAS1 protein levels in cystic fibrosis epithelium
    • Kelley TJ and Elmer HL. In vivo alterations of IFN regulatory factor-1 and PIAS1 protein levels in cystic fibrosis epithelium. J Clin Invest 106: 403-140, 2000.
    • (2000) J Clin Invest , vol.106 , pp. 403-140
    • Kelley, T.J.1    Elmer, H.L.2
  • 14
    • 0034997191 scopus 로고    scopus 로고
    • Proinflammatory cytokine responses to P. aeruginosa infection in human airway epithelial cell lines
    • Kube D, Sontich U, Fletcher D, and Davis PB. Proinflammatory cytokine responses to P. aeruginosa infection in human airway epithelial cell lines. Am J Physiol Lung Cell Mol Physiol 280: L493-L502, 2001.
    • (2001) Am J Physiol Lung Cell Mol Physiol , vol.280
    • Kube, D.1    Sontich, U.2    Fletcher, D.3    Davis, P.B.4
  • 16
    • 0037041024 scopus 로고    scopus 로고
    • Activation of p53 by protein inhibitor of activated Statl (PIAS1)
    • Megidish T, Xu JH, and Xu CW. Activation of p53 by protein inhibitor of activated Statl (PIAS1). J Biol Chem 277: 8255-8259, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 8255-8259
    • Megidish, T.1    Xu, J.H.2    Xu, C.W.3
  • 19
    • 0033935251 scopus 로고    scopus 로고
    • Inhibition of Rho protein stimulates iNOS expression in rat vascular smooth muscle cells
    • Muniyappa R, Xu R, Ram JL, and Sowers JR. Inhibition of Rho protein stimulates iNOS expression in rat vascular smooth muscle cells. Am J Physiol Heart Circ Physiol 278: H1762-H1768, 2000.
    • (2000) Am J Physiol Heart Circ Physiol , vol.278
    • Muniyappa, R.1    Xu, R.2    Ram, J.L.3    Sowers, J.R.4
  • 20
    • 0037022564 scopus 로고    scopus 로고
    • Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity
    • Schmidt D and Muller S. Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity. Proc Natl Acad Sci USA 99: 2872-2877, 2002.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 2872-2877
    • Schmidt, D.1    Muller, S.2
  • 21
    • 0036432880 scopus 로고    scopus 로고
    • ABCA1: Regulation, trafficking and association with heteromeric proteins
    • Schmitz G and Buechler C. ABCA1: regulation, trafficking and association with heteromeric proteins. Ann Med 34: 334-347, 2002.
    • (2002) Ann Med , vol.34 , pp. 334-347
    • Schmitz, G.1    Buechler, C.2
  • 22
    • 0032955681 scopus 로고    scopus 로고
    • Chemokine expression in CF epithelia: Implications for the role of CFTR in RANTES expression
    • Schwiebert LM, Estell K, and Propst SM. Chemokine expression in CF epithelia: implications for the role of CFTR in RANTES expression. Am J Physiol Cell Physiol 276: C700-C710, 1999.
    • (1999) Am J Physiol Cell Physiol , vol.276
    • Schwiebert, L.M.1    Estell, K.2    Propst, S.M.3
  • 23
    • 0035824511 scopus 로고    scopus 로고
    • Constitutive activation of NF-kappa B and secretion of interleukin-8 induced by the G protein-coupled receptor of Kaposi's sarcoma-associated herpes virus involve G alpha(13) and RhoA
    • Shepard LW, Yang M, Xie P, Browning DD, Voyno-Yasenetskaya T, Kozasa T, and Ye RD. Constitutive activation of NF-kappa B and secretion of interleukin-8 induced by the G protein-coupled receptor of Kaposi's sarcoma-associated herpes virus involve G alpha(13) and RhoA. J Biol Chem 276: 45979-45987, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 45979-45987
    • Shepard, L.W.1    Yang, M.2    Xie, P.3    Browning, D.D.4    Voyno-Yasenetskaya, T.5    Kozasa, T.6    Ye, R.D.7
  • 25
    • 0034077631 scopus 로고    scopus 로고
    • Cystic fibrosis transmembrane conductance regulator-dependent regulation of epithelial inducible nitric oxide synthase expression
    • Steagall WK, Elmer HL, Brady KG, and Kelley TJ. Cystic fibrosis transmembrane conductance regulator-dependent regulation of epithelial inducible nitric oxide synthase expression. Am J Respir Cell Mol Biol 22: 45-50, 2000.
    • (2000) Am J Respir Cell Mol Biol , vol.22 , pp. 45-50
    • Steagall, W.K.1    Elmer, H.L.2    Brady, K.G.3    Kelley, T.J.4
  • 26
    • 0034810160 scopus 로고    scopus 로고
    • Accumulation of RhoA, RhoB, RhoG, and Rac1 in fibroblasts from Tangier disease subjects suggests a regulatory role of Rho family proteins in cholesterol efflux
    • Utech M, Hobbel G, Rust S, Reinecke H, Assmann G, and Walter M. Accumulation of RhoA, RhoB, RhoG, and Rac1 in fibroblasts from Tangier disease subjects suggests a regulatory role of Rho family proteins in cholesterol efflux. Biochem Biophys Res Commun 280: 229-236, 2001.
    • (2001) Biochem Biophys Res Commun , vol.280 , pp. 229-236
    • Utech, M.1    Hobbel, G.2    Rust, S.3    Reinecke, H.4    Assmann, G.5    Walter, M.6
  • 31
    • 0037470146 scopus 로고    scopus 로고
    • Transcriptional adaptation to cystic fibrosis transmembrane conductance regulator deficiency
    • Xu Y, Clark JC, Aronow BJ, Dey CR, Liu C, Wooldridge JL, and Whitsett JA. Transcriptional adaptation to cystic fibrosis transmembrane conductance regulator deficiency. J Biol Chem 278: 7674-7682, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 7674-7682
    • Xu, Y.1    Clark, J.C.2    Aronow, B.J.3    Dey, C.R.4    Liu, C.5    Wooldridge, J.L.6    Whitsett, J.A.7
  • 32
    • 0037298507 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitor enhances inducible nitric oxide synthase expression in rat vascular smooth muscle cells; involvement of the Rho/Rho kinase pathway
    • Yamamoto T, Takeda K, Harada S, Nakata T, Azuma A, Sasaki S, and Nakagawa M. HMG-CoA reductase inhibitor enhances inducible nitric oxide synthase expression in rat vascular smooth muscle cells; involvement of the Rho/Rho kinase pathway. Atherosclerosis 166: 213-222, 2003.
    • (2003) Atherosclerosis , vol.166 , pp. 213-222
    • Yamamoto, T.1    Takeda, K.2    Harada, S.3    Nakata, T.4    Azuma, A.5    Sasaki, S.6    Nakagawa, M.7
  • 33
    • 0036901591 scopus 로고    scopus 로고
    • Substance P-stimulated interleukin-8 expression in human colonic epithelial cells involves Rho family small GTPases
    • Zhao D, Kuhnt-Moore S, Zeng H, Pan A, Wu JS, Simeonidis S, Moyer MP, and Pothoulakis C. Substance P-stimulated interleukin-8 expression in human colonic epithelial cells involves Rho family small GTPases. Biochem J 368: 665-672, 2002.
    • (2002) Biochem J , vol.368 , pp. 665-672
    • Zhao, D.1    Kuhnt-Moore, S.2    Zeng, H.3    Pan, A.4    Wu, J.S.5    Simeonidis, S.6    Moyer, M.P.7    Pothoulakis, C.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.