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Volumn 6, Issue 3, 2008, Pages 0581-0600

Phagocytic receptor CED-1 initiates a signaling pathway for degrading engulfed apoptotic cells

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH ABNORMAL 1 PROTEIN; DYNAMIN I; GUANOSINE TRIPHOSPHATASE; MEMBRANE PROTEIN; PHOSPHATIDYLINOSITOL 3 PHOSPHATE; RAB7 PROTEIN; UNCLASSIFIED DRUG; CAENORHABDITIS ELEGANS PROTEIN; CED 1 PROTEIN, C ELEGANS; CED-1 PROTEIN, C ELEGANS; GUANOSINE TRIPHOSPHATE; INOSITOL 1,4,5 TRISPHOSPHATE; RAB PROTEIN;

EID: 41749109981     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.0060061     Document Type: Article
Times cited : (105)

References (60)
  • 1
    • 33646867879 scopus 로고    scopus 로고
    • Yu X, Odera S, Chuang CH, Lu N, Zhou Z (2006) C. elegans Dynamin mediates the signaling of phagocytic receptor CED-1 for the engulfment and degradation of apoptotic cells. Dev Cell 10: 743-757.
    • Yu X, Odera S, Chuang CH, Lu N, Zhou Z (2006) C. elegans Dynamin mediates the signaling of phagocytic receptor CED-1 for the engulfment and degradation of apoptotic cells. Dev Cell 10: 743-757.
  • 2
    • 0034641931 scopus 로고    scopus 로고
    • Corpse clearance defines the meaning of cell death
    • Savill J, Fadok V (2000) Corpse clearance defines the meaning of cell death. Nature 407: 784-788.
    • (2000) Nature , vol.407 , pp. 784-788
    • Savill, J.1    Fadok, V.2
  • 3
    • 0037321024 scopus 로고    scopus 로고
    • Impaired thymic development in mouse embryos deficient in apoptotic DNA degradation
    • Kawane K, Fukuyama H, Yoshida H, Nagase H, Ohsawa Y, et al. (2003) Impaired thymic development in mouse embryos deficient in apoptotic DNA degradation. Nat Immunol 4: 138-144.
    • (2003) Nat Immunol , vol.4 , pp. 138-144
    • Kawane, K.1    Fukuyama, H.2    Yoshida, H.3    Nagase, H.4    Ohsawa, Y.5
  • 4
    • 33847342216 scopus 로고    scopus 로고
    • Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages
    • Kawane K, Ohtani M, Miwa K, Kizawa T, Kanbara Y, et al. (2007) Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages. Nature 446: 102.
    • (2007) Nature , vol.446 , pp. 102
    • Kawane, K.1    Ohtani, M.2    Miwa, K.3    Kizawa, T.4    Kanbara, Y.5
  • 5
  • 7
    • 0036216769 scopus 로고    scopus 로고
    • Phagocytosis of microbes: Complexity in action
    • Underhill DM, Ozinsky A (2002) Phagocytosis of microbes: complexity in action. Annu Rev Immunol 20: 825-852.
    • (2002) Annu Rev Immunol , vol.20 , pp. 825-852
    • Underhill, D.M.1    Ozinsky, A.2
  • 8
    • 0042691817 scopus 로고    scopus 로고
    • Phagosomes fuse with late endosomes and/or lysosomes by extension of membrane protrusions along microtubules: Role of Rab7 and RILP
    • Harrison RE, Bucci C, Vieira OV, Schroer TA, Grinstein S (2003) Phagosomes fuse with late endosomes and/or lysosomes by extension of membrane protrusions along microtubules: role of Rab7 and RILP. Mol Cell Biol 23: 6494-6506.
    • (2003) Mol Cell Biol , vol.23 , pp. 6494-6506
    • Harrison, R.E.1    Bucci, C.2    Vieira, O.V.3    Schroer, T.A.4    Grinstein, S.5
  • 9
    • 0034918862 scopus 로고    scopus 로고
    • Rab7 regulates phagosome maturation in Dictyostelium
    • Rupper A, Grove B, Cardelli J (2001) Rab7 regulates phagosome maturation in Dictyostelium. J Cell Sci 114: 2449-2460.
    • (2001) J Cell Sci , vol.114 , pp. 2449-2460
    • Rupper, A.1    Grove, B.2    Cardelli, J.3
  • 10
    • 33748084030 scopus 로고    scopus 로고
    • Differential regulation of phagosome maturation in macrophages and dendritic cells mediated by Rho GTPases and ezrin-radixin-moesin (ERM) proteins
    • Erwig LP, McPhilips KA, Wynes MW, Ivetic A, Ridley AJ, et al. (2006) Differential regulation of phagosome maturation in macrophages and dendritic cells mediated by Rho GTPases and ezrin-radixin-moesin (ERM) proteins. Proc Natl Acad Sci U S A 103: 12825-12830.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 12825-12830
    • Erwig, L.P.1    McPhilips, K.A.2    Wynes, M.W.3    Ivetic, A.4    Ridley, A.J.5
  • 11
    • 8444252166 scopus 로고    scopus 로고
    • The engulfment process of programmed cell death in Caenorhabditis elegans
    • Reddien PW, Horvitz HR (2004) The engulfment process of programmed cell death in Caenorhabditis elegans. Annu Rev Cell Dev Biol 20: 193-221.
    • (2004) Annu Rev Cell Dev Biol , vol.20 , pp. 193-221
    • Reddien, P.W.1    Horvitz, H.R.2
  • 12
    • 0020858899 scopus 로고
    • The embryonic cell lineage of the nematode Caenorhabditis elegans
    • Sulston JE, Schierenberg E, White JG, Thomson N (1983) The embryonic cell lineage of the nematode Caenorhabditis elegans. Dev Biol 100: 64-119.
    • (1983) Dev Biol , vol.100 , pp. 64-119
    • Sulston, J.E.1    Schierenberg, E.2    White, J.G.3    Thomson, N.4
  • 13
    • 16644368157 scopus 로고    scopus 로고
    • Zhou Z, Mangahas PM, Yu X (2004) The genetics of hiding the corpse: engulfment and degradation of apoptotic cells in C. elegans and D. melanogaster. Curr Top Dev Biol 63: 91-143.
    • Zhou Z, Mangahas PM, Yu X (2004) The genetics of hiding the corpse: engulfment and degradation of apoptotic cells in C. elegans and D. melanogaster. Curr Top Dev Biol 63: 91-143.
  • 14
    • 15944373937 scopus 로고    scopus 로고
    • Clearance of apoptotic cells in Caenorhabditis elegans
    • Mangahas PM, Zhou Z (2005) Clearance of apoptotic cells in Caenorhabditis elegans. Semin Cell Dev Biol 16: 295-306.
    • (2005) Semin Cell Dev Biol , vol.16 , pp. 295-306
    • Mangahas, P.M.1    Zhou, Z.2
  • 15
    • 0035846903 scopus 로고    scopus 로고
    • CED-1 is a transmembrane receptor that mediates cell corpse engulfment in C. elegans
    • Zhou Z, Hartwieg E, Horvitz HR (2001b) CED-1 is a transmembrane receptor that mediates cell corpse engulfment in C. elegans. Cell 104: 43-56.
    • (2001) Cell , vol.104 , pp. 43-56
    • Zhou, Z.1    Hartwieg, E.2    Horvitz, H.R.3
  • 16
    • 14544290056 scopus 로고    scopus 로고
    • Two pathways converge at CED-10 to mediate actin rearrangement and corpse removal in C. elegans
    • Kinchen JM, Cabello J, Klingele D, Wong K, Feichtinger R, et al. (2005) Two pathways converge at CED-10 to mediate actin rearrangement and corpse removal in C. elegans. Nature 434: 93-99.
    • (2005) Nature , vol.434 , pp. 93-99
    • Kinchen, J.M.1    Cabello, J.2    Klingele, D.3    Wong, K.4    Feichtinger, R.5
  • 17
    • 0026051936 scopus 로고
    • Genes required for the engulfment of cell corpses during programmed cell death in Caenorhabditis elegans
    • Ellis RE, Jacobson DM, Horvitz HR (1991a) Genes required for the engulfment of cell corpses during programmed cell death in Caenorhabditis elegans. Genetics 129: 79-94.
    • (1991) Genetics , vol.129 , pp. 79-94
    • Ellis, R.E.1    Jacobson, D.M.2    Horvitz, H.R.3
  • 18
    • 0035487646 scopus 로고    scopus 로고
    • The C. elegans PH domain protein CED-12 regulates cytoskeletal reorganization via a Rho/Rac GTPase signaling pathway
    • Zhou Z, Caron E, Hartwieg E, Hall A, Horvitz HR (2001) The C. elegans PH domain protein CED-12 regulates cytoskeletal reorganization via a Rho/Rac GTPase signaling pathway. Dev Cell 1: 477-489.
    • (2001) Dev Cell , vol.1 , pp. 477-489
    • Zhou, Z.1    Caron, E.2    Hartwieg, E.3    Hall, A.4    Horvitz, H.R.5
  • 19
    • 0035899869 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-phosphate is generated in phagosomal membranes
    • Ellson CD, Anderson KE, Morgan G, Chilvers ER, Lipp P, et al. (2001) Phosphatidylinositol 3-phosphate is generated in phagosomal membranes. Curr Biol 11: 1631-1635.
    • (2001) Curr Biol , vol.11 , pp. 1631-1635
    • Ellson, C.D.1    Anderson, K.E.2    Morgan, G.3    Chilvers, E.R.4    Lipp, P.5
  • 20
    • 0035494493 scopus 로고    scopus 로고
    • Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation
    • Vieira OV, Botelho RJ, Rameh L, Brachmann SM, Matsuo T, et al. (2001) Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation. J Cell Biol 155: 19-25.
    • (2001) J Cell Biol , vol.155 , pp. 19-25
    • Vieira, O.V.1    Botelho, R.J.2    Rameh, L.3    Brachmann, S.M.4    Matsuo, T.5
  • 22
    • 0037007215 scopus 로고    scopus 로고
    • Membrane transport in Caenorhabditis elegans: An essential role for VPS34 at the nuclear membrane
    • Roggo L, Bernard V, Kovacs AL, Rose AM, Savoy F, et al. (2002) Membrane transport in Caenorhabditis elegans: an essential role for VPS34 at the nuclear membrane. EMBO J 21: 1673-1683.
    • (2002) EMBO J , vol.21 , pp. 1673-1683
    • Roggo, L.1    Bernard, V.2    Kovacs, A.L.3    Rose, A.M.4    Savoy, F.5
  • 23
    • 38749093303 scopus 로고    scopus 로고
    • The small GTPase Rab2 functions in the removal of apoptotic cells in Caenorhabditis elegans
    • Mangahas PM, Yu X, Miller KG, Zhou Z (2008) The small GTPase Rab2 functions in the removal of apoptotic cells in Caenorhabditis elegans. J Cell Biol 180: 357-373.
    • (2008) J Cell Biol , vol.180 , pp. 357-373
    • Mangahas, P.M.1    Yu, X.2    Miller, K.G.3    Zhou, Z.4
  • 24
    • 33644850339 scopus 로고    scopus 로고
    • RAB-10 is required for endocytic recycling in the Caenorhabditis elegans intestine
    • Chen CC, Schweinsberg PJ, Vashist S, Mareiniss DP, Lambie EJ, et al. (2006) RAB-10 is required for endocytic recycling in the Caenorhabditis elegans intestine. Mol Biol Cell 17: 1286-1297.
    • (2006) Mol Biol Cell , vol.17 , pp. 1286-1297
    • Chen, C.C.1    Schweinsberg, P.J.2    Vashist, S.3    Mareiniss, D.P.4    Lambie, E.J.5
  • 25
    • 33745584383 scopus 로고    scopus 로고
    • The phosphoinositide kinase PIKfyve/Fab1p regulates terminal lysosome maturation in Caenorhabditis elegans
    • Nicot AS, Fares H, Payrastre B, Chisholm AD, Labouesse M, et al. (2006) The phosphoinositide kinase PIKfyve/Fab1p regulates terminal lysosome maturation in Caenorhabditis elegans. Mol Biol Cell 17: 3062-3074.
    • (2006) Mol Biol Cell , vol.17 , pp. 3062-3074
    • Nicot, A.S.1    Fares, H.2    Payrastre, B.3    Chisholm, A.D.4    Labouesse, M.5
  • 26
    • 0027525104 scopus 로고
    • The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme
    • Yuan J, Shaham S, Ledoux S, Ellis HM, Horvitz HR (1993) The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme. Cell 75: 641-652.
    • (1993) Cell , vol.75 , pp. 641-652
    • Yuan, J.1    Shaham, S.2    Ledoux, S.3    Ellis, H.M.4    Horvitz, H.R.5
  • 27
    • 0033026027 scopus 로고    scopus 로고
    • Genetic control of programmed cell death in the Caenorhabditis elegans hermaphrodite germline
    • Gumienny TL, Lambie E, Hartwieg E, Horvitz HR, Hengartner MO (1999) Genetic control of programmed cell death in the Caenorhabditis elegans hermaphrodite germline. Development 126: 1011-1022.
    • (1999) Development , vol.126 , pp. 1011-1022
    • Gumienny, T.L.1    Lambie, E.2    Hartwieg, E.3    Horvitz, H.R.4    Hengartner, M.O.5
  • 28
    • 0033679966 scopus 로고    scopus 로고
    • A conserved checkpoint pathway mediates DNA damage-induced apoptosis and cell cycle arrest in C. elegans
    • Gartner A, Milstein S, Ahmed S, Hodgkin J, Hengartner MO (2000) A conserved checkpoint pathway mediates DNA damage-induced apoptosis and cell cycle arrest in C. elegans. Mol Cell 5: 435-443.
    • (2000) Mol Cell , vol.5 , pp. 435-443
    • Gartner, A.1    Milstein, S.2    Ahmed, S.3    Hodgkin, J.4    Hengartner, M.O.5
  • 29
    • 0032734242 scopus 로고    scopus 로고
    • Receptor-mediated endocytosis in the Caenorhabditis elegans oocyte
    • Grant B, Hirsh D (1999) Receptor-mediated endocytosis in the Caenorhabditis elegans oocyte. Mol Biol Cell 10: 4311-4326.
    • (1999) Mol Biol Cell , vol.10 , pp. 4311-4326
    • Grant, B.1    Hirsh, D.2
  • 30
    • 0031945551 scopus 로고    scopus 로고
    • A novel gene encoding an integral membrane protein is mutated in nephropathic cystinosis
    • Town M, Jean G, Cherqui S, Attard M, Forestier L, et al. (1998) A novel gene encoding an integral membrane protein is mutated in nephropathic cystinosis. Nat Genet 18: 319-324.
    • (1998) Nat Genet , vol.18 , pp. 319-324
    • Town, M.1    Jean, G.2    Cherqui, S.3    Attard, M.4    Forestier, L.5
  • 31
    • 0035503565 scopus 로고    scopus 로고
    • Cystinosin, the protein defective in cystinosis, is a H(+)-driven lysosomal cystine transporter
    • Kalatzis V, Cherqui S, Antignac C, Gasnier B (2001) Cystinosin, the protein defective in cystinosis, is a H(+)-driven lysosomal cystine transporter. EMBO J 20: 5940-5949.
    • (2001) EMBO J , vol.20 , pp. 5940-5949
    • Kalatzis, V.1    Cherqui, S.2    Antignac, C.3    Gasnier, B.4
  • 32
    • 33846549315 scopus 로고    scopus 로고
    • Caenorhabditis elegans SAND-1 is essential for RAB-7 function in endosomal traffic
    • Poteryaev D, Fares H, Bowerman B, Spang A (2007) Caenorhabditis elegans SAND-1 is essential for RAB-7 function in endosomal traffic. EMBO J 26: 301-312.
    • (2007) EMBO J , vol.26 , pp. 301-312
    • Poteryaev, D.1    Fares, H.2    Bowerman, B.3    Spang, A.4
  • 33
    • 1842428593 scopus 로고    scopus 로고
    • Caenorhabditis elegans functional orthologue of human protein h-mucolipin-1 is required for lysosome biogenesis
    • Treusch S, Knuth S, Slaugenhaupt SA, Goldin E, Grant BD, et al. (2004) Caenorhabditis elegans functional orthologue of human protein h-mucolipin-1 is required for lysosome biogenesis. Proc Natl Acad Sci U SA 101: 4483-4488.
    • (2004) Proc Natl Acad Sci U SA , vol.101 , pp. 4483-4488
    • Treusch, S.1    Knuth, S.2    Slaugenhaupt, S.A.3    Goldin, E.4    Grant, B.D.5
  • 34
    • 0024021909 scopus 로고
    • Identification of a putative structural gene for cathepsin D in Caenorhabditis elegans
    • Jacobson LA, Jen-Jacobson L, Hawdon JM, Owens GP, Bolanowski MA, et al. (1988) Identification of a putative structural gene for cathepsin D in Caenorhabditis elegans. Genetics 119: 355-363.
    • (1988) Genetics , vol.119 , pp. 355-363
    • Jacobson, L.A.1    Jen-Jacobson, L.2    Hawdon, J.M.3    Owens, G.P.4    Bolanowski, M.A.5
  • 35
    • 0033529717 scopus 로고    scopus 로고
    • The TRA-1A sex determination protein of C. elegans regulates sexually dimorphic cell deaths by repressing the egl-1 cell death activator gene
    • Conradt B, Horvitz HR (1999) The TRA-1A sex determination protein of C. elegans regulates sexually dimorphic cell deaths by repressing the egl-1 cell death activator gene. Cell 98: 317-327.
    • (1999) Cell , vol.98 , pp. 317-327
    • Conradt, B.1    Horvitz, H.R.2
  • 36
    • 0035257013 scopus 로고    scopus 로고
    • Rab proteins as membrane organizers
    • Zerial M, McBride H (2001) Rab proteins as membrane organizers. Nat Rev Mol Cell Biol 2: 107-117.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 107-117
    • Zerial, M.1    McBride, H.2
  • 37
    • 0029585762 scopus 로고
    • Rab 7: An important regulator of late endocytic membrane traffic
    • Feng Y, Press B, Wandinger-Ness A (1995) Rab 7: an important regulator of late endocytic membrane traffic. J Cell Biol 131: 1435-1452.
    • (1995) J Cell Biol , vol.131 , pp. 1435-1452
    • Feng, Y.1    Press, B.2    Wandinger-Ness, A.3
  • 38
    • 0031032509 scopus 로고    scopus 로고
    • The small GTP binding protein rab7 is essential for cellular vacuolation induced by Helicobacter pylori cytotoxin
    • Papini E, Satin B, Bucci C, de Bernard M, Telford JL, et al. (1997) The small GTP binding protein rab7 is essential for cellular vacuolation induced by Helicobacter pylori cytotoxin. Embo J 16: 15-24.
    • (1997) Embo J , vol.16 , pp. 15-24
    • Papini, E.1    Satin, B.2    Bucci, C.3    de Bernard, M.4    Telford, J.L.5
  • 39
    • 0034672007 scopus 로고    scopus 로고
    • Sequential action of two GTPases to promote vacuole docking and fusion
    • Eitzen G, Will E, Gallwitz D, Haas A, Wickner W (2000) Sequential action of two GTPases to promote vacuole docking and fusion. EMBO J 19: 6713-6720.
    • (2000) EMBO J , vol.19 , pp. 6713-6720
    • Eitzen, G.1    Will, E.2    Gallwitz, D.3    Haas, A.4    Wickner, W.5
  • 40
    • 0032473981 scopus 로고    scopus 로고
    • Wu Y, Horvitz HR (1998b) C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180. Nature 392: 501-504.
    • Wu Y, Horvitz HR (1998b) C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180. Nature 392: 501-504.
  • 41
    • 0032511234 scopus 로고    scopus 로고
    • Candidate adaptor protein CED-6 promotes the engulfment of apoptotic cells in C. elegans
    • Liu QA, Hengartner MO (1998) Candidate adaptor protein CED-6 promotes the engulfment of apoptotic cells in C. elegans. Cell 93: 961-972.
    • (1998) Cell , vol.93 , pp. 961-972
    • Liu, Q.A.1    Hengartner, M.O.2
  • 42
    • 20244378061 scopus 로고    scopus 로고
    • Chemical genetics identifies Rab geranylgeranyl transferase as an apoptotic target of farnesyl transferase inhibitors
    • Lackner MR, Kindt RM, Carroll PM, Brown K, Cancilla MR, et al. (2005) Chemical genetics identifies Rab geranylgeranyl transferase as an apoptotic target of farnesyl transferase inhibitors. Cancer Cell 7: 325-336.
    • (2005) Cancer Cell , vol.7 , pp. 325-336
    • Lackner, M.R.1    Kindt, R.M.2    Carroll, P.M.3    Brown, K.4    Cancilla, M.R.5
  • 45
    • 24144442691 scopus 로고    scopus 로고
    • Rab conversion as a mechanism of progression from early to late endosomes
    • Rink J, Ghigo E, Kalaidzidis Y, Zerial M (2005) Rab conversion as a mechanism of progression from early to late endosomes. Cell 122: 735-749.
    • (2005) Cell , vol.122 , pp. 735-749
    • Rink, J.1    Ghigo, E.2    Kalaidzidis, Y.3    Zerial, M.4
  • 46
    • 0033855658 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis and Legionella pneumophila phagosomes exhibit arrested maturation despite acquisition of Rab7
    • Clemens DL, Lee BY, Horwitz MA (2000) Mycobacterium tuberculosis and Legionella pneumophila phagosomes exhibit arrested maturation despite acquisition of Rab7. Infect Immun 68: 5154-5166.
    • (2000) Infect Immun , vol.68 , pp. 5154-5166
    • Clemens, D.L.1    Lee, B.Y.2    Horwitz, M.A.3
  • 47
    • 0242485924 scopus 로고    scopus 로고
    • The rab7 GTPase controls the maturation of Salmonella typhimurium-containing vacuoles in HeLa cells
    • Meresse S, Steele-Mortimer O, Finlay BB, Gorvel JP (1999) The rab7 GTPase controls the maturation of Salmonella typhimurium-containing vacuoles in HeLa cells. EMBO J 18: 4394-4403.
    • (1999) EMBO J , vol.18 , pp. 4394-4403
    • Meresse, S.1    Steele-Mortimer, O.2    Finlay, B.B.3    Gorvel, J.P.4
  • 48
    • 0030960157 scopus 로고    scopus 로고
    • Arrest of mycobacterial phagosome maturation is caused by a block in vesicle fusion between stages controlled by rab5 and rab7
    • Via LE, Deretic D, Ulmer RJ, Hibler NS, Huber LA, et al. (1997) Arrest of mycobacterial phagosome maturation is caused by a block in vesicle fusion between stages controlled by rab5 and rab7. J Biol Chem 272: 13326-13331.
    • (1997) J Biol Chem , vol.272 , pp. 13326-13331
    • Via, L.E.1    Deretic, D.2    Ulmer, R.J.3    Hibler, N.S.4    Huber, L.A.5
  • 49
    • 34247623568 scopus 로고    scopus 로고
    • Coats, tethers, Rabs, and SNAREs work together to mediate the intracellular destination of a transport vesicle
    • Cai H, Reinisch K, Ferro-Novick S (2007) Coats, tethers, Rabs, and SNAREs work together to mediate the intracellular destination of a transport vesicle. Dev Cell 12: 671-682.
    • (2007) Dev Cell , vol.12 , pp. 671-682
    • Cai, H.1    Reinisch, K.2    Ferro-Novick, S.3
  • 50
    • 0141452262 scopus 로고    scopus 로고
    • Phosphoinositide involvement in phagocytosis and phagosome maturation
    • Botelho RJ, Scott CC, Grinstein S (2004) Phosphoinositide involvement in phagocytosis and phagosome maturation. Curr Top Microbiol Immunol 282: 1-30.
    • (2004) Curr Top Microbiol Immunol , vol.282 , pp. 1-30
    • Botelho, R.J.1    Scott, C.C.2    Grinstein, S.3
  • 51
    • 0033135748 scopus 로고    scopus 로고
    • Signaling pathways in phagocytosis
    • Kwiatkowska K, Sobota A (1999) Signaling pathways in phagocytosis. Bioessays 21: 422-431.
    • (1999) Bioessays , vol.21 , pp. 422-431
    • Kwiatkowska, K.1    Sobota, A.2
  • 53
    • 34249813708 scopus 로고    scopus 로고
    • Inactivation of Cdc42 is necessary for depolymerization of phagosomal F-actin and subsequent phagosomal maturation
    • Lerm M, Brodin VP, Ruishalme I, Stendahl O, Sarndahl E (2007) Inactivation of Cdc42 is necessary for depolymerization of phagosomal F-actin and subsequent phagosomal maturation. J Immunol 178: 7357-7365.
    • (2007) J Immunol , vol.178 , pp. 7357-7365
    • Lerm, M.1    Brodin, V.P.2    Ruishalme, I.3    Stendahl, O.4    Sarndahl, E.5
  • 54
    • 0016063911 scopus 로고
    • The genetics of Caenorhabditis elegans
    • Brenner S (1974) The genetics of Caenorhabditis elegans. Genetics 77: 71-94.
    • (1974) Genetics , vol.77 , pp. 71-94
    • Brenner, S.1
  • 55
    • 41749115873 scopus 로고    scopus 로고
    • Riddle DL, Blumenthal T, Meyer BJ, Priess JR, editors (1997) C. elegans II. Plainview (New York): Cold Spring harbor Laboratory Press. 1222 p.
    • Riddle DL, Blumenthal T, Meyer BJ, Priess JR, editors (1997) C. elegans II. Plainview (New York): Cold Spring harbor Laboratory Press. 1222 p.
  • 56
    • 0034765271 scopus 로고    scopus 로고
    • LG II balancer chromosomes in Caenorhabditis elegans: MT1(II;III) and the mIn1 set of dominantly and recessively marked inversions
    • Edgley ML, Riddle DL (2001) LG II balancer chromosomes in Caenorhabditis elegans: mT1(II;III) and the mIn1 set of dominantly and recessively marked inversions. Mol Genet Genomics 266: 385-395.
    • (2001) Mol Genet Genomics , vol.266 , pp. 385-395
    • Edgley, M.L.1    Riddle, D.L.2
  • 57
    • 0035031192 scopus 로고    scopus 로고
    • Regulation of endocytosis by CUP-5, the Caenorhabditis elegans mucolipin-1 homolog
    • Fares H, Greenwald I (2001) Regulation of endocytosis by CUP-5, the Caenorhabditis elegans mucolipin-1 homolog. Nat Genet 28: 64-68.
    • (2001) Nat Genet , vol.28 , pp. 64-68
    • Fares, H.1    Greenwald, I.2
  • 58
    • 0037007142 scopus 로고    scopus 로고
    • The Caenorhabditis elegans mucolipin-like gene cup-5 is essential for viability and regulates lysosomes in multiple cell types
    • Hersh BM, Hartwieg E, Horvitz HR (2002) The Caenorhabditis elegans mucolipin-like gene cup-5 is essential for viability and regulates lysosomes in multiple cell types. Proc Natl Acad Sci U S A 99: 4355-4360.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 4355-4360
    • Hersh, B.M.1    Hartwieg, E.2    Horvitz, H.R.3
  • 59
    • 0002826554 scopus 로고    scopus 로고
    • Transformation
    • Hope IA, editor, Oxford: Oxford University Press. pp
    • Jin Y (1999) Transformation. In: Hope IA, editor. C elegans, a practical approach. Oxford: Oxford University Press. pp. 69-96.
    • (1999) C elegans, a practical approach , pp. 69-96
    • Jin, Y.1
  • 60
    • 0030965832 scopus 로고    scopus 로고
    • The Caenorhabditis elegans gene unc-76 and its human homologs define a new gene family involved in axonal outgrowth and fasciculation
    • Bloom L, Horvitz HR (1997) The Caenorhabditis elegans gene unc-76 and its human homologs define a new gene family involved in axonal outgrowth and fasciculation. Proc Natl Acad Sci U S A 94: 3414-3419.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 3414-3419
    • Bloom, L.1    Horvitz, H.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.