-
1
-
-
0026006734
-
Stimulation of in vitro murine lymphocyte proliferation by bacterial DNA
-
Messina J. P., Gilkeson G. S., Pisetsky D. S., Stimulation of in vitro murine lymphocyte proliferation by bacterial DNA Journal of Immunology 1991 147 6 1759 1764
-
(1991)
Journal of Immunology
, vol.147
, Issue.6
, pp. 1759-1764
-
-
Messina, J.P.1
Gilkeson, G.S.2
Pisetsky, D.S.3
-
2
-
-
0028931102
-
CpG motifs in bacterial DNA trigger direct B-cell activation
-
Krieg A. M., Yi A.-K., Matson S., CpG motifs in bacterial DNA trigger direct B-cell activation Nature 1995 374 6522 546 549
-
(1995)
Nature
, vol.374
, Issue.6522
, pp. 546-549
-
-
Krieg, A.M.1
Yi, A.-K.2
Matson, S.3
-
3
-
-
0036219195
-
CpG motifs in bacterial DNA and their immune effects
-
Krieg A. M., CpG motifs in bacterial DNA and their immune effects Annual Review of Immunology 2002 20 709 760
-
(2002)
Annual Review of Immunology
, vol.20
, pp. 709-760
-
-
Krieg, A.M.1
-
4
-
-
0021256125
-
Antitumor activity of deoxyribonucleic acid fraction from Mycobacterium bovis BCG. I. Isolation, physicochemical characterization, and antitumor activity
-
Tokunaga T., Yamamoto H., Shimada S., Antitumor activity of deoxyribonucleic acid fraction from Mycobacterium bovis BCG. I. Isolation, physicochemical characterization, and antitumor activity Journal of the National Cancer Institute 1984 72 4 955 962
-
(1984)
Journal of the National Cancer Institute
, vol.72
, Issue.4
, pp. 955-962
-
-
Tokunaga, T.1
Yamamoto, H.2
Shimada, S.3
-
5
-
-
0026625208
-
Unique palindromic sequences in synthetic oligonucleotides are required to induce INF and augment INF-mediated natural killer activity
-
Yamamoto S., Yamamoto T., Kataoka T., Kuramoto E., Yano O., Tokunaga T., Unique palindromic sequences in synthetic oligonucleotides are required to induce INF and augment INF-mediated natural killer activity Journal of Immunology 1992 148 12 4072 4076
-
(1992)
Journal of Immunology
, vol.148
, Issue.12
, pp. 4072-4076
-
-
Yamamoto, S.1
Yamamoto, T.2
Kataoka, T.3
Kuramoto, E.4
Yano, O.5
Tokunaga, T.6
-
6
-
-
0034619794
-
A toll-like receptor recognizes bacterial DNA
-
Hemmi H., Takeuchi O., Kawai T., A toll-like receptor recognizes bacterial DNA Nature 2000 408 6813 740 745
-
(2000)
Nature
, vol.408
, Issue.6813
, pp. 740-745
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
-
8
-
-
40249088259
-
The DNA sugar backbone 2' deoxyribose determines toll-like receptor 9 activation
-
Haas T., Metzger J., Schmitz F., The DNA sugar backbone 2' deoxyribose determines toll-like receptor 9 activation Immunity 2008 28 3 315 323
-
(2008)
Immunity
, vol.28
, Issue.3
, pp. 315-323
-
-
Haas, T.1
Metzger, J.2
Schmitz, F.3
-
9
-
-
0345447639
-
Wagner H: Vaccination with plasmid DNA activates dendritic cells via Toll-like receptor 9 (TLR9) but functions in TLR9-deficient mice
-
Spies B., Hochrein H., Vabulas M., Wagner H: vaccination with plasmid DNA activates dendritic cells via Toll-like receptor 9 (TLR9) but functions in TLR9-deficient mice Journal of Immunology 2003 171 11 5908 5912
-
(2003)
Journal of Immunology
, vol.171
, Issue.11
, pp. 5908-5912
-
-
Spies, B.1
Hochrein, H.2
Vabulas, M.3
-
10
-
-
18644383289
-
Endosomal translocation of vertebrate DNA activates dendritic cells via TLR9-dependent and -independent pathways
-
Yasuda K., Yu P., Kirschning C. J., Endosomal translocation of vertebrate DNA activates dendritic cells via TLR9-dependent and -independent pathways Journal of Immunology 2005 174 10 6129 6136
-
(2005)
Journal of Immunology
, vol.174
, Issue.10
, pp. 6129-6136
-
-
Yasuda, K.1
Yu, P.2
Kirschning, C.J.3
-
11
-
-
30444450839
-
Recognition of cytosolic DNA activates an IRF3-dependent innate immune response
-
Stetson D. B., Medzhitov R., Recognition of cytosolic DNA activates an IRF3-dependent innate immune response Immunity 2006 24 1 93 103
-
(2006)
Immunity
, vol.24
, Issue.1
, pp. 93-103
-
-
Stetson, D.B.1
Medzhitov, R.2
-
13
-
-
33645402377
-
All is not Toll: New pathways in DNA recognition
-
Wagner H., Bauer S., All is not Toll: new pathways in DNA recognition The Journal of Experimental Medicine 2006 203 2 265 268
-
(2006)
The Journal of Experimental Medicine
, vol.203
, Issue.2
, pp. 265-268
-
-
Wagner, H.1
Bauer, S.2
-
14
-
-
34547143110
-
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
-
Takaoka A., Wang Z., Choi M. K., DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response Nature 2007 448 7152 501 505
-
(2007)
Nature
, vol.448
, Issue.7152
, pp. 501-505
-
-
Takaoka, A.1
Wang, Z.2
Choi, M.K.3
-
15
-
-
60749104535
-
HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA
-
Roberts T. L., Idris A., Dunn J. A., HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA Science 2009 323 5917 1057 1060
-
(2009)
Science
, vol.323
, Issue.5917
, pp. 1057-1060
-
-
Roberts, T.L.1
Idris, A.2
Dunn, J.A.3
-
16
-
-
0036570169
-
Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides
-
Hornung V., Rothenfusser S., Britsch S., Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides Journal of Immunology 2002 168 9 4531 4537
-
(2002)
Journal of Immunology
, vol.168
, Issue.9
, pp. 4531-4537
-
-
Hornung, V.1
Rothenfusser, S.2
Britsch, S.3
-
17
-
-
0030240062
-
Macrophages ingest and are activated by bacterial DNA
-
Stacey K. J., Sweet M. J., Hume D. A., Macrophages ingest and are activated by bacterial DNA Journal of Immunology 1996 157 5 2116 2122
-
(1996)
Journal of Immunology
, vol.157
, Issue.5
, pp. 2116-2122
-
-
Stacey, K.J.1
Sweet, M.J.2
Hume, D.A.3
-
18
-
-
0037080024
-
Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines
-
Zarember K. A., Godowski P. J., Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines Journal of Immunology 2002 168 2 554 561
-
(2002)
Journal of Immunology
, vol.168
, Issue.2
, pp. 554-561
-
-
Zarember, K.A.1
Godowski, P.J.2
-
19
-
-
77953488830
-
CpG oligodeoxyribonucleotides rescue mature spleen B cells from spontaneous apoptosis and promote cell cycle entry
-
Yi A.-K., Chang M., Peckham D. W., Krieg A. M., Ashman R. F., CpG oligodeoxyribonucleotides rescue mature spleen B cells from spontaneous apoptosis and promote cell cycle entry Journal of Immunology 1998 161 2223 2231
-
(1998)
Journal of Immunology
, vol.161
, pp. 2223-2231
-
-
Yi, A.-K.1
Chang, M.2
Peckham, D.W.3
Krieg, A.M.4
Ashman, R.F.5
-
20
-
-
13544254614
-
Activation of marginal zone B cells from lupus mice with type A(D) CpG-oligodeoxynucleotides
-
Brummel R., Lenert P., Activation of marginal zone B cells from lupus mice with type A(D) CpG-oligodeoxynucleotides Journal of Immunology 2005 174 4 2429 2434 (Pubitemid 40223993)
-
(2005)
Journal of Immunology
, vol.174
, Issue.4
, pp. 2429-2434
-
-
Brummel, R.1
Lenert, P.2
-
21
-
-
15244349648
-
TLR-9 activation of marginal zone B cells in lupus mice regulates immunity through increased IL-10 production
-
Lenert P., Brummel R., Field E. H., Ashman R. F., TLR-9 activation of marginal zone B cells in lupus mice regulates immunity through increased IL-10 production Journal of Clinical Immunology 2005 25 1 29 40
-
(2005)
Journal of Clinical Immunology
, vol.25
, Issue.1
, pp. 29-40
-
-
Lenert, P.1
Brummel, R.2
Field, E.H.3
Ashman, R.F.4
-
22
-
-
0031867535
-
Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells
-
Sparwasser T., Koch E.-S., Vabulas R. M., Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells European Journal of Immunology 1998 28 6 2045 2054
-
(1998)
European Journal of Immunology
, vol.28
, Issue.6
, pp. 2045-2054
-
-
Sparwasser, T.1
Koch, E.-S.2
Vabulas, R.M.3
-
23
-
-
0035423557
-
An etiopathogenic role for the type i IFN system in SLE
-
Ronnblom L., Alm G. V., An etiopathogenic role for the type I IFN system in SLE Trends in Immunology 2001 22 8 427 431
-
(2001)
Trends in Immunology
, vol.22
, Issue.8
, pp. 427-431
-
-
Ronnblom, L.1
Alm, G.V.2
-
24
-
-
4344617762
-
Interferon-alpha in systemic lupus erythematosus
-
Crow M. K., Kirou K. A., Interferon-alpha in systemic lupus erythematosus Current Opinion in Rheumatology 2004 16 5 541 547
-
(2004)
Current Opinion in Rheumatology
, vol.16
, Issue.5
, pp. 541-547
-
-
Crow, M.K.1
Kirou, K.A.2
-
25
-
-
0033485756
-
Anti-double-stranded DNA antibodies and immunostimulatory plasmid DNA in combination mimic the endogenous IFN- inducer in systemic lupus erythematosus
-
Vallin H., Perers A., Alm G. V., Rnnblom L., Anti-double-stranded DNA antibodies and immunostimulatory plasmid DNA in combination mimic the endogenous IFN- inducer in systemic lupus erythematosus Journal of Immunology 1999 163 11 6306 6313
-
(1999)
Journal of Immunology
, vol.163
, Issue.11
, pp. 6306-6313
-
-
Vallin, H.1
Perers, A.2
Alm, G.V.3
Rnnblom, L.4
-
26
-
-
17244372491
-
Activation of the type i interferon system in primary Sjgren's syndrome: A possible etiopathogenic mechanism
-
Bve U., Nordmark G., Lvgren T., Activation of the type I interferon system in primary Sjgren's syndrome: a possible etiopathogenic mechanism Arthritis and Rheumatism 2005 52 4 1185 1195
-
(2005)
Arthritis and Rheumatism
, vol.52
, Issue.4
, pp. 1185-1195
-
-
Bve, U.1
Nordmark, G.2
Lvgren, T.3
-
27
-
-
48749085121
-
T cell-independent and Toll-like receptor-dependent antigen-driven activation of autoreactive B cells
-
Herlands R. A., Christensen S. R., Sweet R. A., Hershberg U., Shlomchik M. J., T cell-independent and Toll-like receptor-dependent antigen-driven activation of autoreactive B cells Immunity 2008 29 2 249 260
-
(2008)
Immunity
, vol.29
, Issue.2
, pp. 249-260
-
-
Herlands, R.A.1
Christensen, S.R.2
Sweet, R.A.3
Hershberg, U.4
Shlomchik, M.J.5
-
28
-
-
33748472865
-
Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus
-
Christensen S. R., Shupe J., Nickerson K., Kashgarian M., Flavell R. A., Shlomchik M. J., Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus Immunity 2006 25 3 417 428
-
(2006)
Immunity
, vol.25
, Issue.3
, pp. 417-428
-
-
Christensen, S.R.1
Shupe, J.2
Nickerson, K.3
Kashgarian, M.4
Flavell, R.A.5
Shlomchik, M.J.6
-
29
-
-
31044440025
-
Toll-like receptor 9 signaling protects against murine lupus
-
Wu X., Peng S. L., Toll-like receptor 9 signaling protects against murine lupus Arthritis and Rheumatism 2006 54 1 336 342
-
(2006)
Arthritis and Rheumatism
, vol.54
, Issue.1
, pp. 336-342
-
-
Wu, X.1
Peng, S.L.2
-
30
-
-
0032476602
-
CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation
-
Hacker H., Mischak H., Miethke T., CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation EMBO Journal 1998 17 21 6230 6240
-
(1998)
EMBO Journal
, vol.17
, Issue.21
, pp. 6230-6240
-
-
Hacker, H.1
Mischak, H.2
Miethke, T.3
-
31
-
-
0036318851
-
Bacterial CpG-DNA and lipopolysaccharides activate toll-like receptors at distinct cellular compartments
-
Ahmad-Nejad P., Hacker H., Rutz M., Bauer S., Vabulas R. M., Wagner H., Bacterial CpG-DNA and lipopolysaccharides activate toll-like receptors at distinct cellular compartments European Journal of Immunology 2002 32 7 1958 1968
-
(2002)
European Journal of Immunology
, vol.32
, Issue.7
, pp. 1958-1968
-
-
Ahmad-Nejad, P.1
Hacker, H.2
Rutz, M.3
Bauer, S.4
Vabulas, R.M.5
Wagner, H.6
-
32
-
-
0031936182
-
Antagonism of immunostimulatory CpG-oligodeoxynucleotides by quinacrine, chloroquine, and structurally related compounds
-
Macfarlane D. E., Manzel L., Antagonism of immunostimulatory CpG-oligodeoxynucleotides by quinacrine, chloroquine, and structurally related compounds Journal of Immunology 1998 160 3 1122 1131
-
(1998)
Journal of Immunology
, vol.160
, Issue.3
, pp. 1122-1131
-
-
MacFarlane, D.E.1
Manzel, L.2
-
33
-
-
34948862264
-
Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide
-
Lande R., Gregorio J., Facchinetti V., Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide Nature 2007 449 7162 564 569
-
(2007)
Nature
, vol.449
, Issue.7162
, pp. 564-569
-
-
Lande, R.1
Gregorio, J.2
Facchinetti, V.3
-
34
-
-
10744219675
-
TLR9 signals after translocating from the ER to CpG DNA in the lysosome
-
Latz E., Schoenemeyer A., Visintin A., TLR9 signals after translocating from the ER to CpG DNA in the lysosome Nature Immunology 2004 5 2 190 198
-
(2004)
Nature Immunology
, vol.5
, Issue.2
, pp. 190-198
-
-
Latz, E.1
Schoenemeyer, A.2
Visintin, A.3
-
35
-
-
40749098665
-
UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
-
Kim Y.-M., Brinkmann M. M., Paquet M.-E., Ploegh H. L., UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes Nature 2008 452 7184 234 238
-
(2008)
Nature
, vol.452
, Issue.7184
, pp. 234-238
-
-
Kim, Y.-M.1
Brinkmann, M.M.2
Paquet, M.-E.3
Ploegh, H.L.4
-
37
-
-
31344466165
-
The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9
-
Tabeta K., Hoebe K., Janssen E. M., The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9 Nature Immunology 2006 7 2 156 164
-
(2006)
Nature Immunology
, vol.7
, Issue.2
, pp. 156-164
-
-
Tabeta, K.1
Hoebe, K.2
Janssen, E.M.3
-
38
-
-
57349191215
-
The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor
-
Ewald S. E., Lee B. L., Lau L., The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor Nature 2008 456 7222 658 662
-
(2008)
Nature
, vol.456
, Issue.7222
, pp. 658-662
-
-
Ewald, S.E.1
Lee, B.L.2
Lau, L.3
-
39
-
-
70449477746
-
Critical role for asparagine endopeptidase in endocytic Toll-like receptor signaling in dendritic cells
-
Sepulveda F. E., Maschalidi S., Colisson R., Critical role for asparagine endopeptidase in endocytic Toll-like receptor signaling in dendritic cells Immunity 2009 31 5 737 748
-
(2009)
Immunity
, vol.31
, Issue.5
, pp. 737-748
-
-
Sepulveda, F.E.1
Maschalidi, S.2
Colisson, R.3
-
40
-
-
34250698370
-
Ligand-induced conformational changes allosterically activate Toll-like receptor 9
-
Latz E., Verma A., Visintin A., Ligand-induced conformational changes allosterically activate Toll-like receptor 9 Nature Immunology 2007 8 7 772 779
-
(2007)
Nature Immunology
, vol.8
, Issue.7
, pp. 772-779
-
-
Latz, E.1
Verma, A.2
Visintin, A.3
-
41
-
-
0032133278
-
MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways
-
Medzhitov R., Preston-Hurlburt P., Kopp E., MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways Molecular Cell 1998 2 2 253 258
-
(1998)
Molecular Cell
, vol.2
, Issue.2
, pp. 253-258
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Kopp, E.3
-
42
-
-
0034698739
-
Immune cell activation by bacterial CpG-DNA through myeloid differentiation marker 88 and tumor necrosis factor receptor-associated factor (TRAF)6
-
Hacker H., Vabulas R. M., Takeuchi O., Hoshino K., Akira S., Wagner H., Immune cell activation by bacterial CpG-DNA through myeloid differentiation marker 88 and tumor necrosis factor receptor-associated factor (TRAF)6 Journal of Experimental Medicine 2000 192 4 595 600
-
(2000)
Journal of Experimental Medicine
, vol.192
, Issue.4
, pp. 595-600
-
-
Hacker, H.1
Vabulas, R.M.2
Takeuchi, O.3
Hoshino, K.4
Akira, S.5
Wagner, H.6
-
43
-
-
0032526861
-
The human toll signaling pathway: Divergence of nuclear factor b and jnk/sapk activation upstream of tumor necrosis factor receptor-associated factor 6 (TRAF6)
-
Muzio M., Natoli G., Saccani S., Levrero M., Mantovani A., The human toll signaling pathway: divergence of nuclear factor b and jnk/sapk activation upstream of tumor necrosis factor receptor-associated factor 6 (TRAF6) Journal of Experimental Medicine 1998 187 12 2097 2101
-
(1998)
Journal of Experimental Medicine
, vol.187
, Issue.12
, pp. 2097-2101
-
-
Muzio, M.1
Natoli, G.2
Saccani, S.3
Levrero, M.4
Mantovani, A.5
-
44
-
-
2942679083
-
The immunobiology of the TLR9 subfamily
-
Wagner H., The immunobiology of the TLR9 subfamily Trends in Immunology 2004 25 7 381 386
-
(2004)
Trends in Immunology
, vol.25
, Issue.7
, pp. 381-386
-
-
Wagner, H.1
-
45
-
-
39549116503
-
PI3K is critical for the nuclear translocation of IRF-7 and type i IFN production by human plasmacytoid predendritic cells in response to TLR activation
-
Guiducci C., Ghirelli C., Marloie-Provost M.-A., PI3K is critical for the nuclear translocation of IRF-7 and type I IFN production by human plasmacytoid predendritic cells in response to TLR activation Journal of Experimental Medicine 2008 205 2 315 322
-
(2008)
Journal of Experimental Medicine
, vol.205
, Issue.2
, pp. 315-322
-
-
Guiducci, C.1
Ghirelli, C.2
Marloie-Provost, M.-A.3
-
46
-
-
0037407691
-
Activation with CpG-A and CpG-B oligonucleotides reveals two distinct regulatory pathways of type i IFN synthesis in human plasmacytoid dendritic cells
-
Kerkmann M., Rothenfusser S., Hornung V., Activation with CpG-A and CpG-B oligonucleotides reveals two distinct regulatory pathways of type I IFN synthesis in human plasmacytoid dendritic cells Journal of Immunology 2003 170 9 4465 4474
-
(2003)
Journal of Immunology
, vol.170
, Issue.9
, pp. 4465-4474
-
-
Kerkmann, M.1
Rothenfusser, S.2
Hornung, V.3
-
47
-
-
0028832030
-
In vitro inhibition of murine IFN production by phosphorothioate deoxyguanosine oligomers
-
Halpern M. D., Pisetsky D. S., In vitro inhibition of murine IFN production by phosphorothioate deoxyguanosine oligomers Immunopharmacology 1995 29 1 47 52
-
(1995)
Immunopharmacology
, vol.29
, Issue.1
, pp. 47-52
-
-
Halpern, M.D.1
Pisetsky, D.S.2
-
48
-
-
0033843575
-
Inhibition of murine macrophage IL-12 production by natural and synthetic DNA
-
Pisetsky D. S., Reich C. F., Inhibition of murine macrophage IL-12 production by natural and synthetic DNA Clinical Immunology 2000 96 3 198 204
-
(2000)
Clinical Immunology
, vol.96
, Issue.3
, pp. 198-204
-
-
Pisetsky, D.S.1
Reich, C.F.2
-
49
-
-
0036913736
-
Inhibition of murine dendritic cell activation by synthetic phosphorothioate oligodeoxynucleotides
-
Zhu F.-G., Reich C. F., Pisetsky D. S., Inhibition of murine dendritic cell activation by synthetic phosphorothioate oligodeoxynucleotides Journal of Leukocyte Biology 2002 72 6 1154 1163
-
(2002)
Journal of Leukocyte Biology
, vol.72
, Issue.6
, pp. 1154-1163
-
-
Zhu, F.-G.1
Reich, C.F.2
Pisetsky, D.S.3
-
50
-
-
0344984245
-
Targeting Stat3 with G-quartet oligodeoxynucleotides in human cancer cells
-
Jing N., Li Y., Xu X., Targeting Stat3 with G-quartet oligodeoxynucleotides in human cancer cells DNA and Cell Biology 2003 22 11 685 696
-
(2003)
DNA and Cell Biology
, vol.22
, Issue.11
, pp. 685-696
-
-
Jing, N.1
Li, Y.2
Xu, X.3
-
51
-
-
4644325545
-
G-quartet oligonucleotides: A new class of signal transducer and activator of transcription 3 inhibitors that suppresses growth of prostate and breast tumors through induction of apoptosis
-
Jing N., Li Y., Xiong W., Sha W., Jing L., Tweardy D. J., G-quartet oligonucleotides: a new class of signal transducer and activator of transcription 3 inhibitors that suppresses growth of prostate and breast tumors through induction of apoptosis Cancer Research 2004 64 18 6603 6609
-
(2004)
Cancer Research
, vol.64
, Issue.18
, pp. 6603-6609
-
-
Jing, N.1
Li, Y.2
Xiong, W.3
Sha, W.4
Jing, L.5
Tweardy, D.J.6
-
53
-
-
0034932263
-
Identification of methylated CpG motifs as inhibitors of the immune stimulatory CpG motifs
-
Chen Y., Lenert P., Weeratna R., Identification of methylated CpG motifs as inhibitors of the immune stimulatory CpG motifs Gene Therapy 2001 8 13 1024 1032
-
(2001)
Gene Therapy
, vol.8
, Issue.13
, pp. 1024-1032
-
-
Chen, Y.1
Lenert, P.2
Weeratna, R.3
-
54
-
-
0242288068
-
Structural characterization of the inhibitory DNA motif for the type A[D]-CpG-induced cytokine secretion and NK-cell lytic activity in mouse spleen cells
-
Lenert P., Rasmussen W., Ashman R. F., Ballas Z. K., Structural characterization of the inhibitory DNA motif for the type A[D]-CpG-induced cytokine secretion and NK-cell lytic activity in mouse spleen cells DNA and Cell Biology 2003 22 10 621 631
-
(2003)
DNA and Cell Biology
, vol.22
, Issue.10
, pp. 621-631
-
-
Lenert, P.1
Rasmussen, W.2
Ashman, R.F.3
Ballas, Z.K.4
-
55
-
-
17644405409
-
Sequence requirements for oligodeoxyribonucleotide inhibitory activity
-
Ashman R. F., Goeken J. A., Drahos J., Lenert P., Sequence requirements for oligodeoxyribonucleotide inhibitory activity International Immunology 2005 17 4 411 420
-
(2005)
International Immunology
, vol.17
, Issue.4
, pp. 411-420
-
-
Ashman, R.F.1
Goeken, J.A.2
Drahos, J.3
Lenert, P.4
-
56
-
-
0142210343
-
An immunomodulatory GpG oligonucleotide for the treatment of autoimmunity via the innate and adaptive immune systems
-
Ho P. P., Fontoura P., Ruiz P. J., Steinman L., Garren H., An immunomodulatory GpG oligonucleotide for the treatment of autoimmunity via the innate and adaptive immune systems Journal of Immunology 2003 171 9 4920 4926
-
(2003)
Journal of Immunology
, vol.171
, Issue.9
, pp. 4920-4926
-
-
Ho, P.P.1
Fontoura, P.2
Ruiz, P.J.3
Steinman, L.4
Garren, H.5
-
57
-
-
77649289335
-
Treatment with a Toll-like receptor inhibitory GpG oligonucleotide delays and attenuates lupus nephritis in NZB/W mice
-
Graham K. L., Lee L. Y., Higgins J. P., Steinman L., Utz P. J., Ho P. P., Treatment with a Toll-like receptor inhibitory GpG oligonucleotide delays and attenuates lupus nephritis in NZB/W mice Autoimmunity 2010 43 2 140 155
-
(2010)
Autoimmunity
, vol.43
, Issue.2
, pp. 140-155
-
-
Graham, K.L.1
Lee, L.Y.2
Higgins, J.P.3
Steinman, L.4
Utz, P.J.5
Ho, P.P.6
-
58
-
-
0034856551
-
CpG stimulation of primary mouse B cells is blocked by inhibitory oligodeoxyribonucleotides at a site proximal to NF- B activation
-
Lenert P., Stunz L., Yi A.-K., Krieg A. M., Ashman R. F., CpG stimulation of primary mouse B cells is blocked by inhibitory oligodeoxyribonucleotides at a site proximal to NF- B activation Antisense and Nucleic Acid Drug Development 2001 11 4 247 256
-
(2001)
Antisense and Nucleic Acid Drug Development
, vol.11
, Issue.4
, pp. 247-256
-
-
Lenert, P.1
Stunz, L.2
Yi, A.-K.3
Krieg, A.M.4
Ashman, R.F.5
-
59
-
-
0036107449
-
Inhibitory oligonucleotides specifically block effects of stimulatory CpG oligonucleotides in B cells
-
Stunz L. L., Lenert P., Peckham D., Inhibitory oligonucleotides specifically block effects of stimulatory CpG oligonucleotides in B cells European Journal of Immunology 2002 32 5 1212 1222
-
(2002)
European Journal of Immunology
, vol.32
, Issue.5
, pp. 1212-1222
-
-
Stunz, L.L.1
Lenert, P.2
Peckham, D.3
-
60
-
-
24144476236
-
Inhibitory oligonucleotides block the induction of AP-1 transcription factor by stimulatory CpG oligonucleotides in B cells
-
Lenert P., Yi A.-K., Krieg A. M., Stunz L. L., Ashman R. F., Inhibitory oligonucleotides block the induction of AP-1 transcription factor by stimulatory CpG oligonucleotides in B cells Oligonucleotides 2003 13 3 143 150
-
(2003)
Oligonucleotides
, vol.13
, Issue.3
, pp. 143-150
-
-
Lenert, P.1
Yi, A.-K.2
Krieg, A.M.3
Stunz, L.L.4
Ashman, R.F.5
-
61
-
-
0042346153
-
Repetitive elements in mammalian telomeres suppress bacterial DNA-induced immune activation
-
Gursel I., Gursel M., Yamada H., Ishii K. J., Takeshita F., Klinman D. M., Repetitive elements in mammalian telomeres suppress bacterial DNA-induced immune activation Journal of Immunology 2003 171 3 1393 1400
-
(2003)
Journal of Immunology
, vol.171
, Issue.3
, pp. 1393-1400
-
-
Gursel, I.1
Gursel, M.2
Yamada, H.3
Ishii, K.J.4
Takeshita, F.5
Klinman, D.M.6
-
62
-
-
67249139402
-
DNA-like class R inhibitory oligonucleotides (INH-ODNs) preferentially block autoantigen-induced B-cell and dendritic cell activation in vitro and autoantibody production in lupus-prone MRL-Fa slpr/lpr mice in vivo
-
ARTICLE R79
-
Lenert P., Yasuda K., Busconi L., DNA-like class R inhibitory oligonucleotides (INH-ODNs) preferentially block autoantigen-induced B-cell and dendritic cell activation in vitro and autoantibody production in lupus-prone MRL-Fa slpr/lpr mice in vivo Arthritis Research and Therapy 2009 11 3, article R79
-
(2009)
Arthritis Research and Therapy
, vol.11
, Issue.3
-
-
Lenert, P.1
Yasuda, K.2
Busconi, L.3
-
63
-
-
16244423314
-
Inhibitory oligodeoxynucleotidestherapeutic promise for systemic autoimmune diseases?
-
Lenert P., Inhibitory oligodeoxynucleotidestherapeutic promise for systemic autoimmune diseases? Clinical and Experimental Immunology 2005 140 1 1 10
-
(2005)
Clinical and Experimental Immunology
, vol.140
, Issue.1
, pp. 1-10
-
-
Lenert, P.1
-
64
-
-
17844383756
-
Inhibitors of TLR-9 act on multiple cell subsets in mouse and man in vitro and prevent death in vivo from systemic inflammation
-
Duramad O., Fearon K. L., Chang B., Inhibitors of TLR-9 act on multiple cell subsets in mouse and man in vitro and prevent death in vivo from systemic inflammation Journal of Immunology 2005 174 9 5193 5200
-
(2005)
Journal of Immunology
, vol.174
, Issue.9
, pp. 5193-5200
-
-
Duramad, O.1
Fearon, K.L.2
Chang, B.3
-
65
-
-
35348918191
-
Structural requirements and applications of inhibitory oligodeoxyribonucleotides
-
Ashman R. F., Lenert P., Structural requirements and applications of inhibitory oligodeoxyribonucleotides Immunologic Research 2007 39 13 4 14
-
(2007)
Immunologic Research
, vol.39
, Issue.13
, pp. 4-14
-
-
Ashman, R.F.1
Lenert, P.2
-
66
-
-
40249088259
-
The DNA sugar backbone 2' deoxyribose determines toll-like receptor 9 activation
-
Haas T., Metzger J., Schmitz F., The DNA sugar backbone 2' deoxyribose determines toll-like receptor 9 activation Immunity 2008 28 3 315 323
-
(2008)
Immunity
, vol.28
, Issue.3
, pp. 315-323
-
-
Haas, T.1
Metzger, J.2
Schmitz, F.3
-
67
-
-
33144458473
-
G-rich DNA suppresses systemic lupus
-
Patole P. S., Zecher D., Pawar R. D., Grone H.-J., Schlondorff D., Anders H.-J., G-rich DNA suppresses systemic lupus Journal of the American Society of Nephrology 2005 16 11 3273 3280
-
(2005)
Journal of the American Society of Nephrology
, vol.16
, Issue.11
, pp. 3273-3280
-
-
Patole, P.S.1
Zecher, D.2
Pawar, R.D.3
Grone, H.-J.4
Schlondorff, D.5
Anders, H.-J.6
-
68
-
-
0037378005
-
The molecular basis for the lack of immunostimulatory activity of vertebrate DNA
-
Stacey K. J., Young G. R., Clark F., The molecular basis for the lack of immunostimulatory activity of vertebrate DNA Journal of Immunology 2003 170 7 3614 3620
-
(2003)
Journal of Immunology
, vol.170
, Issue.7
, pp. 3614-3620
-
-
Stacey, K.J.1
Young, G.R.2
Clark, F.3
-
69
-
-
4644330955
-
Toll-like receptor 9 binds single-stranded CpG-DNA in a sequence- and pH-dependent manner
-
Rutz M., Metzger J., Gellert T., Toll-like receptor 9 binds single-stranded CpG-DNA in a sequence- and pH-dependent manner European Journal of Immunology 2004 34 9 2541 2550
-
(2004)
European Journal of Immunology
, vol.34
, Issue.9
, pp. 2541-2550
-
-
Rutz, M.1
Metzger, J.2
Gellert, T.3
-
70
-
-
2442450672
-
Direct evidence that Toll-like Receptor 9 (TLR9) functionally binds plasmid DNA by specific cytosine-phosphate-guanine motif recognition
-
Cornelie S., Hoebeke J., Schacht A.-M., Direct evidence that Toll-like Receptor 9 (TLR9) functionally binds plasmid DNA by specific cytosine-phosphate-guanine motif recognition Journal of Biological Chemistry 2004 279 15 15124 15129
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.15
, pp. 15124-15129
-
-
Cornelie, S.1
Hoebeke, J.2
Schacht, A.-M.3
-
71
-
-
26844467349
-
Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus
-
Barrat F. J., Meeker T., Gregorio J., Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus Journal of Experimental Medicine 2005 202 8 1131 1139
-
(2005)
Journal of Experimental Medicine
, vol.202
, Issue.8
, pp. 1131-1139
-
-
Barrat, F.J.1
Meeker, T.2
Gregorio, J.3
-
72
-
-
37149024435
-
Characterization of suppressive oligodeoxynucleotides that inhibit Toll-like receptor-9-mediated activation of innate immunity
-
Peter M., Bode K., Lipford G. B., Eberle F., Heeg K., Dalpke A. H., Characterization of suppressive oligodeoxynucleotides that inhibit Toll-like receptor-9-mediated activation of innate immunity Immunology 2008 123 1 118 128
-
(2008)
Immunology
, vol.123
, Issue.1
, pp. 118-128
-
-
Peter, M.1
Bode, K.2
Lipford, G.B.3
Eberle, F.4
Heeg, K.5
Dalpke, A.H.6
-
73
-
-
0027468768
-
Polynucleotide binding to macrophage scavenger receptors depends on the formation of base-quartet-stabilized four-stranded helices
-
Pearson A. M., Rich A., Krieger M., Polynucleotide binding to macrophage scavenger receptors depends on the formation of base-quartet-stabilized four-stranded helices Journal of Biological Chemistry 1993 268 5 3546 3554
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.5
, pp. 3546-3554
-
-
Pearson, A.M.1
Rich, A.2
Krieger, M.3
-
74
-
-
62849104051
-
TLR9-independent effects of inhibitory oligonucleotides on macrophage responses to S. typhimurium
-
Trieu A., Bokil N., Dunn J. A., TLR9-independent effects of inhibitory oligonucleotides on macrophage responses to S. typhimurium Immunology and Cell Biology 2009 87 3 218 225
-
(2009)
Immunology and Cell Biology
, vol.87
, Issue.3
, pp. 218-225
-
-
Trieu, A.1
Bokil, N.2
Dunn, J.A.3
-
75
-
-
33144467291
-
Targeting Toll-like receptor signaling in plasmacytoid dendritic cells and autoreactive B cells as a therapy for lupus
-
ARTICLE R203
-
Lenert P. S., Targeting Toll-like receptor signaling in plasmacytoid dendritic cells and autoreactive B cells as a therapy for lupus Arthritis Research and Therapy 2006 8 1, article R203
-
(2006)
Arthritis Research and Therapy
, vol.8
, Issue.1
-
-
Lenert, P.S.1
-
76
-
-
17844380477
-
Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction
-
Honda K., Ohba Y., Yanai H., Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction Nature 2005 434 7036 1035 1040
-
(2005)
Nature
, vol.434
, Issue.7036
, pp. 1035-1040
-
-
Honda, K.1
Ohba, Y.2
Yanai, H.3
-
77
-
-
33746884630
-
Properties regulating the nature of the plasmacytoid dendritic cell response to Toll-like receptor 9 activation
-
Guiducci C., Ott G., Chan J. H., Properties regulating the nature of the plasmacytoid dendritic cell response to Toll-like receptor 9 activation Journal of Experimental Medicine 2006 203 8 1999 2008
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.8
, pp. 1999-2008
-
-
Guiducci, C.1
Ott, G.2
Chan, J.H.3
-
78
-
-
77953275701
-
Differential cytokine production and bystander activation of autoreactive B cells in response to CpG-A and CpG-B oligonucleotides
-
Avalos A. M., Latz E., Mousseau B., Differential cytokine production and bystander activation of autoreactive B cells in response to CpG-A and CpG-B oligonucleotides Journal of Immunology 2009 183 8 6262 6268
-
(2009)
Journal of Immunology
, vol.183
, Issue.8
, pp. 6262-6268
-
-
Avalos, A.M.1
Latz, E.2
Mousseau, B.3
-
79
-
-
0035865054
-
Human peripheral blood cells differentially recognize and respond to two distinct CpG motifs
-
Verthelyi D., Ishii K. J., Gursel M., Takeshita F., Klinman D. M., Human peripheral blood cells differentially recognize and respond to two distinct CpG motifs Journal of Immunology 2001 166 4 2372 2377
-
(2001)
Journal of Immunology
, vol.166
, Issue.4
, pp. 2372-2377
-
-
Verthelyi, D.1
Ishii, K.J.2
Gursel, M.3
Takeshita, F.4
Klinman, D.M.5
-
80
-
-
0034933019
-
Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmocytoid dendritic cells
-
Krug A., Rothenfusser S., Hornung V., Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmocytoid dendritic cells European Journal of Immunology 2001 31 7 2154 2163
-
(2001)
European Journal of Immunology
, vol.31
, Issue.7
, pp. 2154-2163
-
-
Krug, A.1
Rothenfusser, S.2
Hornung, V.3
-
81
-
-
20244367698
-
Spontaneous formation of nucleic acid-based nanoparticles is responsible for high interferon- induction by CpG-A in plasmacytoid dendritic cells
-
Kerkmann M., Costa L. T., Richter C., Spontaneous formation of nucleic acid-based nanoparticles is responsible for high interferon- induction by CpG-A in plasmacytoid dendritic cells Journal of Biological Chemistry 2005 280 9 8086 8093
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.9
, pp. 8086-8093
-
-
Kerkmann, M.1
Costa, L.T.2
Richter, C.3
-
82
-
-
77953481282
-
A role for Toll-like receptors in acquired immunity: Up-regulation of TLR9 by BCR triggering in nave B cells and constitutive expression in memory B cells
-
Bernasconi N. L., Onai N., Lanzavecchia A., A role for Toll-like receptors in acquired immunity: up-regulation of TLR9 by BCR triggering in nave B cells and constitutive expression in memory B cells Blood 2003 102 11 956 63
-
(2003)
Blood
, vol.102
, Issue.11
, pp. 956-63
-
-
Bernasconi, N.L.1
Onai, N.2
Lanzavecchia, A.3
-
83
-
-
33645956556
-
Toll-like receptor stimulation as a third signal required for activation of human naive B cells
-
Ruprecht C. R., Lanzavecchia A., Toll-like receptor stimulation as a third signal required for activation of human naive B cells European Journal of Immunology 2006 36 4 810 816
-
(2006)
European Journal of Immunology
, vol.36
, Issue.4
, pp. 810-816
-
-
Ruprecht, C.R.1
Lanzavecchia, A.2
-
84
-
-
33746238512
-
Higher-order CpG-DNA stimulation reveals distinct activation requirements for marginal zone and follicular B cells in lupus mice
-
Brummel R., Roberts T. L., Stacey K. J., Lenert P., Higher-order CpG-DNA stimulation reveals distinct activation requirements for marginal zone and follicular B cells in lupus mice European Journal of Immunology 2006 36 7 1951 1962
-
(2006)
European Journal of Immunology
, vol.36
, Issue.7
, pp. 1951-1962
-
-
Brummel, R.1
Roberts, T.L.2
Stacey, K.J.3
Lenert, P.4
-
85
-
-
11144353781
-
Plasmacytoid dendritic cells, antigen, and CpG-C license human B cells for plasma cell differentiation and immunoglobulin production in the absence of T-cell help
-
Poeck H., Wagner M., Battiany J., Plasmacytoid dendritic cells, antigen, and CpG-C license human B cells for plasma cell differentiation and immunoglobulin production in the absence of T-cell help Blood 2004 103 8 3058 3064
-
(2004)
Blood
, vol.103
, Issue.8
, pp. 3058-3064
-
-
Poeck, H.1
Wagner, M.2
Battiany, J.3
-
86
-
-
38849175552
-
Functional outcome of B cell activation by chromatin immune complex engagement of the B cell receptor and TLR9
-
Busconi L., Bauer J. W., Tumang J. R., Functional outcome of B cell activation by chromatin immune complex engagement of the B cell receptor and TLR9 Journal of Immunology 2007 179 11 7397 7405
-
(2007)
Journal of Immunology
, vol.179
, Issue.11
, pp. 7397-7405
-
-
Busconi, L.1
Bauer, J.W.2
Tumang, J.R.3
-
87
-
-
0029854905
-
A disease-related rheumatoid factor autoantibody is not tolerized in a normal mouse: Implications for the origins of autoantibodies in autoimmune disease
-
Hannum L. G., Ni D., Haberman A. M., Weigert M. G., Shlomchik M. J., A disease-related rheumatoid factor autoantibody is not tolerized in a normal mouse: implications for the origins of autoantibodies in autoimmune disease Journal of Experimental Medicine 1996 184 4 1269 1278
-
(1996)
Journal of Experimental Medicine
, vol.184
, Issue.4
, pp. 1269-1278
-
-
Hannum, L.G.1
Ni, D.2
Haberman, A.M.3
Weigert, M.G.4
Shlomchik, M.J.5
-
88
-
-
0037061453
-
Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors
-
Leadbetter E. A., Rifkin I. R., Hohlbaum A. M., Beaudette B. C., Shlomchik M. J., Marshak-Rothstein A., Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors Nature 2002 416 6881 603 607
-
(2002)
Nature
, vol.416
, Issue.6881
, pp. 603-607
-
-
Leadbetter, E.A.1
Rifkin, I.R.2
Hohlbaum, A.M.3
Beaudette, B.C.4
Shlomchik, M.J.5
Marshak-Rothstein, A.6
-
89
-
-
27744444832
-
RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement
-
Lau C. M., Broughton C., Tabor A. S., RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement Journal of Experimental Medicine 2005 202 9 1171 1177
-
(2005)
Journal of Experimental Medicine
, vol.202
, Issue.9
, pp. 1171-1177
-
-
Lau, C.M.1
Broughton, C.2
Tabor, A.S.3
-
90
-
-
0030953632
-
Roles of interferon-gamma and interleukin-4 in murine lupus
-
Peng S. L., Moslehi J., Craft J., Roles of interferon-gamma and interleukin-4 in murine lupus Journal of Clinical Investigation 1997 99 8 1936 1946
-
(1997)
Journal of Clinical Investigation
, vol.99
, Issue.8
, pp. 1936-1946
-
-
Peng, S.L.1
Moslehi, J.2
Craft, J.3
-
91
-
-
0031155269
-
IFN-gamma is essential for the development of autoimmune glomerulonephritis in MRL/lpr mice
-
Haas C., Ryffel B., Le Hir M., IFN-gamma is essential for the development of autoimmune glomerulonephritis in MRL/lpr mice Journal of Immunology 1997 158 11 5484 5491
-
(1997)
Journal of Immunology
, vol.158
, Issue.11
, pp. 5484-5491
-
-
Haas, C.1
Ryffel, B.2
Le Hir, M.3
-
92
-
-
3242805826
-
Type i IFN protects against murine lupus
-
Hron J. D., Peng S. L., Type I IFN protects against murine lupus Journal of Immunology 2004 173 3 2134 2142
-
(2004)
Journal of Immunology
, vol.173
, Issue.3
, pp. 2134-2142
-
-
Hron, J.D.1
Peng, S.L.2
-
94
-
-
70349453647
-
Therapeutic applications and mechanisms underlying the activity of immunosuppressive oligonucleotides
-
Klinman D. M., Tross D., Klaschik S., Shirota H., Sato T., Therapeutic applications and mechanisms underlying the activity of immunosuppressive oligonucleotides Annals of the New York Academy of Sciences 2009 1175 80 88
-
(2009)
Annals of the New York Academy of Sciences
, vol.1175
, pp. 80-88
-
-
Klinman, D.M.1
Tross, D.2
Klaschik, S.3
Shirota, H.4
Sato, T.5
-
95
-
-
6344262317
-
Suppressive oligodeoxynucleotides inhibit Th1 differentiation by blocking IFN-gamma and IL-12-mediated signaling
-
Shirota H., Gursel M., Klinman D. M., Suppressive oligodeoxynucleotides inhibit Th1 differentiation by blocking IFN-gamma and IL-12-mediated signaling Journal of Immunology 2004 173 8 5002 5007
-
(2004)
Journal of Immunology
, vol.173
, Issue.8
, pp. 5002-5007
-
-
Shirota, H.1
Gursel, M.2
Klinman, D.M.3
-
96
-
-
0031750415
-
Interferon-gamma-inhibitory oligodeoxynucleotides alter the conformation of interferon-gamma
-
Balasubramanian V., Nguyen L. T., Balasubramanian S. V., Ramanathan M., Interferon-gamma-inhibitory oligodeoxynucleotides alter the conformation of interferon-gamma Molecular Pharmacology 1998 53 5 926 932
-
(1998)
Molecular Pharmacology
, vol.53
, Issue.5
, pp. 926-932
-
-
Balasubramanian, V.1
Nguyen, L.T.2
Balasubramanian, S.V.3
Ramanathan, M.4
-
97
-
-
0037637548
-
Influence of stimulatory and suppressive DNA motifs on host susceptibility to inflammatory arthritis
-
Zeuner R. A., Verthelyi D., Gursel M., Ishii K. J., Klinman D. M., Influence of stimulatory and suppressive DNA motifs on host susceptibility to inflammatory arthritis Arthritis and Rheumatism 2003 48 6 1701 1707
-
(2003)
Arthritis and Rheumatism
, vol.48
, Issue.6
, pp. 1701-1707
-
-
Zeuner, R.A.1
Verthelyi, D.2
Gursel, M.3
Ishii, K.J.4
Klinman, D.M.5
-
98
-
-
13444302229
-
Suppressive oligodeoxynucleotides delay the onset of glomerulonephritis and prolong survival in lupus-prone NZB x NZW mice
-
Dong L., Ito S., Ishii K. J., Klinman D. M., Suppressive oligodeoxynucleotides delay the onset of glomerulonephritis and prolong survival in lupus-prone NZB x NZW mice Arthritis and Rheumatism 2005 52 2 651 658
-
(2005)
Arthritis and Rheumatism
, vol.52
, Issue.2
, pp. 651-658
-
-
Dong, L.1
Ito, S.2
Ishii, K.J.3
Klinman, D.M.4
-
99
-
-
47249095737
-
Suppressive oligodeoxynucleotides inhibit silica-induced pulmonary inflammation
-
Sato T., Shimosato T., Alvord W. G., Klinman D. M., Suppressive oligodeoxynucleotides inhibit silica-induced pulmonary inflammation Journal of Immunology 2008 180 11 7648 7654
-
(2008)
Journal of Immunology
, vol.180
, Issue.11
, pp. 7648-7654
-
-
Sato, T.1
Shimosato, T.2
Alvord, W.G.3
Klinman, D.M.4
-
100
-
-
17044423406
-
Suppressive oligodeoxynucleotides protect mice from lethal endotoxic shock
-
Shirota H., Gursel I., Gursel M., Klinman D. M., Suppressive oligodeoxynucleotides protect mice from lethal endotoxic shock Journal of Immunology 2005 174 8 4579 4583
-
(2005)
Journal of Immunology
, vol.174
, Issue.8
, pp. 4579-4583
-
-
Shirota, H.1
Gursel, I.2
Gursel, M.3
Klinman, D.M.4
-
101
-
-
0033034413
-
High affinity interactions of nucleolin with G-G-paired rDNA
-
Hanakahi L. A., Sun H., Maizels N., High affinity interactions of nucleolin with G-G-paired rDNA Journal of Biological Chemistry 1999 274 22 15908 15912
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.22
, pp. 15908-15912
-
-
Hanakahi, L.A.1
Sun, H.2
Maizels, N.3
-
103
-
-
45149129895
-
Toll-like receptor 9 inhibition reduces mortality in polymicrobial sepsis
-
Plitas G., Burt B. M., Nguyen H. M., Bamboat Z. M., DeMatteo R. P., Toll-like receptor 9 inhibition reduces mortality in polymicrobial sepsis Journal of Experimental Medicine 2008 205 6 1277 1283
-
(2008)
Journal of Experimental Medicine
, vol.205
, Issue.6
, pp. 1277-1283
-
-
Plitas, G.1
Burt, B.M.2
Nguyen, H.M.3
Bamboat, Z.M.4
Dematteo, R.P.5
-
104
-
-
37549066665
-
Treatment of lupus-prone mice with a dual inhibitor of TLR7 and TLR9 leads to reduction of autoantibody production and amelioration of disease symptoms
-
Barrat F. J., Meeker T., Chan J. H., Guiducci C., Coffmann R. L., Treatment of lupus-prone mice with a dual inhibitor of TLR7 and TLR9 leads to reduction of autoantibody production and amelioration of disease symptoms European Journal of Immunology 2007 37 12 3582 3586
-
(2007)
European Journal of Immunology
, vol.37
, Issue.12
, pp. 3582-3586
-
-
Barrat, F.J.1
Meeker, T.2
Chan, J.H.3
Guiducci, C.4
Coffmann, R.L.5
-
105
-
-
6344227970
-
Expansion of bone marrow IFN-alpha-producing dendritic cells in New Zealand Black (NZB) mice: High level expression of TLR9 and secretion of IFN-alpha in NZB bone marrow
-
Lian Z.-X., Kikuchi K., Yang G.-X., Ansari A. A., Ikehara S., Gershwin M. E., Expansion of bone marrow IFN-alpha-producing dendritic cells in New Zealand Black (NZB) mice: high level expression of TLR9 and secretion of IFN-alpha in NZB bone marrow Journal of Immunology 2004 173 8 5283 5289
-
(2004)
Journal of Immunology
, vol.173
, Issue.8
, pp. 5283-5289
-
-
Lian, Z.-X.1
Kikuchi, K.2
Yang, G.-X.3
Ansari, A.A.4
Ikehara, S.5
Gershwin, M.E.6
-
107
-
-
28544449709
-
Immune stimulation mediated by autoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8
-
Vollmer J., Tluk S., Schmitz C., Immune stimulation mediated by autoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8 Journal of Experimental Medicine 2005 202 11 1575 1585
-
(2005)
Journal of Experimental Medicine
, vol.202
, Issue.11
, pp. 1575-1585
-
-
Vollmer, J.1
Tluk, S.2
Schmitz, C.3
-
108
-
-
33746266273
-
Modulating responsiveness of human TLR7 and 8 to small molecule ligands with T-rich phosphorothiate oligodeoxynucleotides
-
Jurk M., Kritzler A., Schulte B., Modulating responsiveness of human TLR7 and 8 to small molecule ligands with T-rich phosphorothiate oligodeoxynucleotides European Journal of Immunology 2006 36 7 1815 1826
-
(2006)
European Journal of Immunology
, vol.36
, Issue.7
, pp. 1815-1826
-
-
Jurk, M.1
Kritzler, A.2
Schulte, B.3
-
109
-
-
33751565283
-
Oligodeoxynucleotides differentially modulate activation of TLR7 and TLR8 by imidazoquinolines
-
Gorden K. K. B., Qiu X., Battiste J. J. L., Wightman P. P. D., Vasilakos J. P., Alkan S. S., Oligodeoxynucleotides differentially modulate activation of TLR7 and TLR8 by imidazoquinolines Journal of Immunology 2006 177 11 8164 8170
-
(2006)
Journal of Immunology
, vol.177
, Issue.11
, pp. 8164-8170
-
-
Gorden, K.K.B.1
Qiu, X.2
Battiste, J.J.L.3
Wightman, P.P.D.4
Vasilakos, J.P.5
Alkan, S.S.6
-
110
-
-
33746214827
-
CXCL16 influences the nature and specificity of CpG-induced immune activation
-
Gursel M., Gursel I., Mostowski H. S., Klinman D. M., CXCL16 influences the nature and specificity of CpG-induced immune activation Journal of Immunology 2006 177 3 1575 1580
-
(2006)
Journal of Immunology
, vol.177
, Issue.3
, pp. 1575-1580
-
-
Gursel, M.1
Gursel, I.2
Mostowski, H.S.3
Klinman, D.M.4
-
111
-
-
33847049885
-
DNA motifs suppressing TLR9 responses
-
Trieu A., Roberts T. L., Dunn J. A., Sweet M. J., Stacey K. J., DNA motifs suppressing TLR9 responses Critical Reviews in Immunology 2006 26 6 527 544
-
(2006)
Critical Reviews in Immunology
, vol.26
, Issue.6
, pp. 527-544
-
-
Trieu, A.1
Roberts, T.L.2
Dunn, J.A.3
Sweet, M.J.4
Stacey, K.J.5
-
112
-
-
56349114913
-
Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9
-
Park B., Brinkmann M. M., Spooner E., Lee C. C., Kim Y.-M., Ploegh H. L., Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9 Nature Immunology 2008 9 12 1407 1414
-
(2008)
Nature Immunology
, vol.9
, Issue.12
, pp. 1407-1414
-
-
Park, B.1
Brinkmann, M.M.2
Spooner, E.3
Lee, C.C.4
Kim, Y.-M.5
Ploegh, H.L.6
-
113
-
-
34249915031
-
Inhibition of Toll-like receptor-7 (TLR-7) or TLR-7 plus TLR-9 attenuates glomerulonephritis and lung injury in experimental lupus
-
Pawar R. D., Ramanjaneyulu A., Kulkarni O. P., Lech M., Segerer S., Anders H.-J., Inhibition of Toll-like receptor-7 (TLR-7) or TLR-7 plus TLR-9 attenuates glomerulonephritis and lung injury in experimental lupus Journal of the American Society of Nephrology 2007 18 6 1721 1731
-
(2007)
Journal of the American Society of Nephrology
, vol.18
, Issue.6
, pp. 1721-1731
-
-
Pawar, R.D.1
Ramanjaneyulu, A.2
Kulkarni, O.P.3
Lech, M.4
Segerer, S.5
Anders, H.-J.6
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